>f ..-r ■■/. ■' THE STETHOSCOPE, VIRGINIA MEDICAL GAZETTE MONTHLY JOURNAL JtlcMcitu ani tl)£ Collateral Sriences. EDITED BY P. CLAIBORNE GOOCH, A. M., M. D. ONE OF THE SECRETARIES OF THE AMERICAN MEDICAL ASSOCIATION, AND SECRETARY OF THE MEDICAL SOCIETY OF VIRGINIA— FELLOW OF THE PATHOLOGICAL SOCIETY OF MONTREAL AND OF THE PARISIAN MEDICAL SOCIETY, ETC. 'Medicine is enriched "by facts only." — Bboussais. VOL, I. RICHMOND : PRINTED BY RITCHIES & DUNNAVANT. 1851. ft 52 THIS VOLUME CONTAINS ORIGINAL PAPERS FROM THE FOLLOWING CONTRIBUTORS: L. B. Anderson, M. D. G. W. Ashby, M. D. James Bolton, M. D. John J. Boswell, M. D. W. S. Bowyer, M. D. D. W. Brodnax, M. D. J. N. Broocks, M. D. Wm. M. Broocks, M. D. Wm. Browne, M. D., Pres't Med. Society Fredericksburg. P. H. Cabell, M. D. Robt. G. Cabell, M. D. J. H. Claiborne, M. D. G. Lane Corbin, M. D. J. B. Davies, M. D. F. H. Deane, M. D. Thos. Dunn, M. D. J. R. Elsome, M. D. D. S. Evans, M. D. W. B. Evans, M. D. J. M. Gait, M. D., Phys, and Supt. Eastern Lunatic Asylum. T. J. Garden, M. D. S. C. Gholson, M. D. P. C. Gooch, M. D. P. H. Grigg, M. D. W. D. Haskins, M. D. R. W. Haxall, M. D. M. H. Houston, M. D. R. E. Jennings, M. D. R. G. Jennings, M. D. C. P. Johnson, M. D., Prof. Anat. and Phys. Hamp. Sid. Med. Col. W. F. Jones, M. D. L. S. Joynes, M. D. Joseph Laidley, Pharmaceutist. Zachary Lewis, M. D. Harvey Lindsly, M. D. J. P. Little, M. D. R. L. Madison, M. D. J. C. Marcks, M. D. O. F. Manson, M. D. D. T. Martin, M. D. W. D. Meriwether, M. D. A. T. B. Merritt, M. D. J. P. Mettauer, M. D., Prof. Med. Sfc. Rand. Macon Med. College. C. R. Palmore, M. D. J. F. Peebles, M. D. Thomas Pollard, M. D. M. P. Scott, M. D. Albert Snead, M. D. J. Snyder, M. D. P. C. Spencer, M. D. J. J. Thweatt, M. D. J. W. H. Trugien, M. D. A. B. Tucker, M. D. T. J. Young, M. D. J. Wistar Walke, M. D. G. A. Wilson. M. D. TH£ AND Ho. 1. RICHMOND, JANUARY 1851. [Vol. I. INTRODUCTION. In embarking upon the arduous and responsible task of establishing and editing a monthly medical journal in Virginia, we deem it due to those upon whose pa- tronage and support we are dependent, to set forth our views and intentions at some length. The establishment of a medical press in Virginia has been a long- cherished desire of the whole profession. In 18-16, in convention assembled, the report of a committee urging the establishment of a journal was unanimously adopted ; but, from various causes, no one hitherto has volunteered to risk the la- bor and expense of the undertaking. In doing so ourselves, we naturally felt some doubts and misgivings as to the success of our enterprise. These, however, have been totally dispelled by the flattering and earnest assurances of assistance — (with- out which we feel incompetent to the task) — which we have already received from many of our zealous professional brethren, in every direction. It is proper to say, that our determination to assume the important post which we occupy dates no fur- ther back than the past month. In the short space of 30 days all the arrangements were to be made to put into operation a monthly publication. Arrangements with publishers — securing original matter and contributors, the making known our intention and obtaining subscribers — all to be done at once — were embarrassments which cannot be readily appreciated by the uninitiated. These disadvantages be- ing met, we found another source of perplexity, viz: the selection of a name ; and it being a matter of considerable moment, gave much concern. To choose one which would please everybody we knew was impossible, and to select one which would give satisfaction to the greatest number presented no little difficulty. We accordingly communed with many professional friends, of the best judgment and taste, both far and near, for aid ; and, after the most mature consultation about a matter of so little real importance, the Stethoscope was selected. As some have already criticised the election, it may be well to allege some reasons in its favor. There are so many "Journals," "Gazettes," "Recorders," "Examiners," and other similar titles already in circulation, that none of those seemed eligible. The aptness of a name after some important professional instrument, had been at- tested by the "Lancet," " Scalpel," &c. The " Stethoscope," then, Avas deem- ed particularly adapted, as the name of a work not devoted to any particular de- partment, but to medicine generally. It is an instrument used in each of the prac- tical divisions of our art, and is a valuable means for obtaining information — Z INTRODUCTION. such, may we hope, will be our Stethoscope. Its devotion to auscultation will he no more exclusive than is that of the "London Lancet" to venesection, or the " Scalpel" to dissections. So much for the name — it being satisfactory to us, we hope that it will not be the source of any sort of prejudice with others. The objects of this journal scarcely need to be explained. We desire our pages to be the medium for drawing more closely the bonds of professional union, and for encouraging that esprit du corps among our brethren, which is so essential to their well being. We will labor in the advancement of medical science and its literature in Virginia and the South generally ; to aid in drawing into active use- fulness the great fund of information and talent which is now dormant; to collect and diffuse all the facts which medical science is rapidly developing, both in our own country and abroad; to suppress empiricism and charlatanry, both legitimate and illegitimate ; and to favor the protection and fostering of the science of me- dicine, by sound and effectual enactments of legislature, and to lend our mite in the " elevation of the science from the position of a trade to that of a noble profes- sion." Much is to be done for the interests of medical men, now not only neglected entirely by law, but most shamefully oppressed. In the reform and the movement in favor of medicine, which it is hoped will soon be effected, we wish " to let the professional voice be heard on professional questions," and through an organ which will afford every facility for that interchange of investigation, experience and opinion among those engaged in active practice, which is so valuable in a progressive science — and which is as abundant and valuable in our own as in an}' other country. All agree that it is high time for the South to be building up itself and advancing its own institutions — its own medical schools and literature. To these ends will our energies be directed. We will be governed by those rules and principles laid down by the " American Medical Association," and oppose every innovation upon them. Having no party to favor — no sinister purposes to ad- vance, we will pursue steadily the course here laid down ; and though it may oc- casionally be our duty to take positions, and strive to establish them, in opposition to some of our brethren, we will ever be actuated by high and pure motives — will act promptly and decisively, according to the best lights before us — and in the discharge of the delicate duties incident to the editorial chair, to the best of our feeble ability, we hope to retain the friendship of all, and merit the enmity of none. Being desirous of making our work interesting in all the branches, we invite practical communications upon the subjects of chemistry, pharmacy, botany, and every subject of medical interest, as well as of medicine and surgery. And, finally, as the work must surely die without support, we solicit the patronage of the pro- fession by their liberal subscription. HAXALL ON UTERINE HAEMORRHAGE. A few Remarks on the subject of Uterine Hemorrhage, limited to cases of Placenta Previa and those which occur subsequent to the completion of Labor. BY ROBT. W. HAXALL, M. D. Not intending to enter into an examination of the several modes by which it was attempted to explain the occurrence of flooding at the time of labor, I will merely remark, that it was clearly understood at an early period that the placenta might in some way or other be- come attached near to, or over the mouth of, the womb in such manner as to give rise to haemorrhage during its dilatation. Suffice it to say, that the first complete description of this kind of haemorrhage was furnished by R aederer in his Elementa artis Obstetricia, published about eighty 3rears ago. Hemorrhage occurring in a case of placenta praevia, has been very properly denominated unavoidable; and it is so, because, to use the words of Prof. Naegele, " the very action which nature uses to bring the child into the world, is that by which she oftentimes destroys both it and its mother." In this sense it is clearly distinguishable from ac- cidental haemorrhage, which may happen at any period of gestation, and against which we have to contend in the common and ordinary forms of abortion. The causes of placenta praevia are not, it must be admitted, fully understood. The most generally received opinion, I believe, is, that the semi-fluid condition of the decidua at this very early period of preg- nancy, does not always present a force sufficient to retain the ovum in the superior portion of the uterus. Hence it is that it has been supposed to glide down between the deciduous membrane and the uterine pari- etes, until finally arrested at the os internum. The manner of its ar- restation is seen to be different in different cases ; and we may sa,y, that in proportion to its direct implantation over the os internum, is the danger to be estimated by which both mother and child are threatened. As just intimated, this central implantation may exist; at other times a portion only of placenta is observed to overhang the dilating os tincae ; and fortunate for the patient is it, when this complication exists in no greater degree. The eruption of haemorrhage, in cases of placenta praevia, is confined to the latter months of gestation ; it is never perhaps noticed earlier than the sixth month ; much more frequently is it entirely unobserved until a month or six weeks before the period of accouchement, and this- is the case, for reasons which must suggest themselves to the minds of all. The appearance of haermorrhage is sudden and unexpected — -unex- pected because the woman cannot recal to mind any act of impru- dence by which it might have been induced. It is more abundant than accidental haemorrhage ; and particularly is' it so, the nearer the patient has approached the period of parturition. Should1 she have two or three months, yet to go before reaching thfeterm, the flooding will not be so profuse ; but the probability is that a return of it will be 4 HAXALL ON UTERINE HEMORRHAGE. experienced every twelve or fifteen days. There is also a very con- siderable difference in one respect, between accidental and unavoid- able haemorrhage ; in the latter, the eruption of blood shews itself during the 'presence of pain, for very obvious reasons, and diminishes when this subsides ; while in the former the reverse of this is found to be the case. When the symptoms which I have here detailed exist, there is much reason to dread the existence of placenta praevia. A resort to the touch however will very frequently impart sufficient information to dispel our doubts ; not always however with entire accuracy, because the os tincae is at this stage of gestation so high up in the hollow of the sacrum as to render the touch somewhat obscure. It may, to be sure, be reached if the whole hand is introduced, and I would not hesitate thus to act, if I could not otherwise gain the desired information. By whatever method we may reach the os uteri, it will be found to be more bulky and much softer than in ordinary gestation, for the reason that its vessels are enlarged and distended, as are those of any other portion of the organ where the placenta may happen to be attached. When the finger penetrates the cervix, if there be a partial implanta- tion of the placenta, it will be felt overlapping one side, while upon the other we may recognize the distended membranes, and in all pro- bability be enabled to distinguish the presenting portion of the foetus. If the implantation be central, the finger comes in contact with a soft, spongy body, which is found to be attached throughout the whole cir- cumference of the os internum. This diversity in the mode of the placental implantation will clear- ly explain to us the characters which belong to haemorrhage connected with this complication. It is unquestionably true that the most alarm- ing and profuse gushings of blood take place when the after-birth is centrally attached ; for every pain but serves to separate more and more the connection which exists between it and the womb. Under these circumstances, awful and appalling in the extreme, are we sometimes called upon to act ; and our action can admit of no delay ; for if the case be left to nature, the unhappy patient is sure to find a bloody grave ; — and how are we to act ? The ingenuity of the profession has devised several means, to which the intelligent accoucheur will imme- diately resort, according to the varying circumstances of the case — means which sometimes succeed, but which, it must be confessed, are too often inadequate to the end. Where the placenta is but partially attached, the haemorrhage will not be so profuse, and the danger is consequently less. Should the uterine pains be sufficiently active, and the placenta overlap a small portion only of the os uteri, the case may demand but little interfer- ence ; for the bag of waters will more or less protrude through the gradually dilating os, and thus serve as a compress by which the flood- ing will be measurably commanded. If the presenting placenta cover a large portion of the os tincae, the tampon ma}7- in such a case be used with advantage, in order to afford time for its dilatation. Should the flooding however prostrate too much the powers of the patient, the finger may be passed through the unobstructed portion of the os tincae HAXALL ON UTERINE HEMORRHAGE. 5 and the membranes ruptured. By this process we gain the advantage of causing the uterus to contract with more energy, and perhaps the greater one of bringing down the head immediately upon the mouth of the womb ; by which manoeuvre it is made to act the part of a com- press, and thus becomes instrumental in arresting the further flow of blood. As the pains cause the head to advance, the less becomes the danger ; and so soon as the delivery of the foetus takes place, in the generality of instances the placenta follows without delay. It is scarcely necessary to add, that the patient may require pretty active stimulation should the loss of blood have been considerable, as well as the use of ergot, should the pains not be sufficiently energetic. Should haemorrhage supervene at any early period, whether the pla- centa be partially or centrally implanted, we ought to make no forcible effort to enter the os tinea?. All our endeavors should tend to mode- rate the flooding, and conduct the patient to the latest period of ges- tation. A contrary course would ensure the death of the child in all human probability ; nor would it redound to the well-being of the woman. The remedy adapted to this condition of things, in the first place, is bleeding if the patient is feverish, with a quick and active pulse, as frequently happens ; the bowels should be emptied by an enema or laxative, and cold applications assiduously applied ; and should the uterine pains become at all expulsive or harrassing, they may be calmed by opiates and anodyne injections. The administration of lead and opium will also prove beneficial. At this period of gestation these measures will often be effectual without the aid of the tampon; indeed the tampon is objectionable at this stage, because its presence might become a source of irritation to the uterus, and thereby increase the activity of the expulsive efforts. Let us now proceed to consider the case in which the placenta is centrally attached ; and I need not remark, that here the most alarm- ing difficulties are presented. At every recurrence of pain the hae- morrhage is increased necessarily, and without the most prompt and well-directed action the patient inevitably succumbs. The main object to be attained is to rid the womb of its contents with as much despatch as may be consistent with the safety of the woman; and how shall this be done ? The method uniformly adopted heretofore, was to turn the child and deliver by the feet. But ano- ther measure has been recently practised, to which I shall frequently call the attention of the reader. The os tincae however may not be sufficiently dilated to admit of the introduction of the hand, and all are agreed that no forcible entry should be attempted. To introduce the hand it must either be dilated or dilatable ; in which latter case a very moderate effort will be sufficient to accomplish our purpose. But suppose that neither con- dition exists ; every returning pain increases the haemorrhage, and if it be not checked the most disastrous results are to be feared. Under these circumstances it is that the tampon is capable of exercising the most beneficial and saving influence ; until the os tineas is sufficiently dilated to admit the hand, we must plug the vagina as speedily as pos- sible. By this method the flooding is greatly checked, if not entire- 6 HAXALL ON UTERINE HAEMORRHAGE. ly arrested ; and during the subsequent dilatation of the os tinea?, which is not at all impeded by the presence of the plug, the haemorrhage is held in check. And here permit me to say a word or two as to the manner in which the vagina should be plugged. One or even two large sponges will not be sufficient for the purpose; the vagina should be completely filled and distended ; and to accomplish this in the most effectual manner, several small pieces of sponge not larger than half the fist should be successively introduced. After accomplishing this, a bandage moderately tight should encircle the body, and the T bandage finally applied. I have had the fullest evidence of the utilit}7- of such a plan. Under its action the os tineas will continue to dilate or become dilatable ; and when this desirable end is attained, we shall have obtained the only practicable condition in which turning can be readily accomplished. How is this to be effected ? Are we forcibly to thrust the hand through the centre of the placental mass, search for the feet, and then proceed to deliver ? By no means ; and without reciting the various arguments against such a procedure, allow me to dismiss this part of the subject by quoting the language of the late Dr. Dewees : " This," he says, "should never be done; especially as it is impossible to assign one single good reason for the practice, and there are several very strong ones against it." But how are we to proceed ? So soon as the hand can be introduced, it should be passed between the os tincae and the placenta, by in- sinuating the fingers carefully, one after the other, if no portion of it be detached ; if any part of its circumference, however, shall have been separated, it is at that point through which the hand will be more easily made to penetrate. When it shall have gained admission, the haemorrhage will at once materially diminish, if it be not entirely sub- dued, just because the arm will most effectually perform the office of a well-adjusted plug. We should now proceed in our search for the feet, endeavoring to retain the membranes entire until this part of the process shall have been accomplished. When we have succeeded in grasping one or both, they are gently to be brought down ; and if the patient be not in the extreme of prostration, we may begin to congratu- late ourselves upon the favorable termination of the case. Like the arm, when introduced, so does the body of the child, as it advances, play the part of a most effectual plug. So soon as the child is deli- vered, the tonic contraction of the womb succeeds as in ordinary cases, and the placenta, the great cause of all the mischief, is speedily thrown into the vagina. In looking over the history of obstetrical medicine, we shall find many cases recorded where the delivery of the placenta preceded the birth of the child ; these were necessarily cases of placenta prasvia. In many of these both mother and child have fallen victims ; the child, I may remark, invariably did — but in some few, the life of the parent was preserved. These facts have been known to the profession for years, but it is only within a comparatively recent period that they have been scrutinized with a scientific eye, and made available in a practical point of view. HAXALL OX UTERINE HEMORRHAGE. 7 In those cases in which the life of the mother has been preserved, the somewhat astonishing fact was observed that the haemorrhage had very much diminished, and in some instances entirely ceased, so soon as the placenta was expelled. Dr. Collins relates a case in which the placenta had been delivered eighteen hours before the birth of the child, and the mother did well. Reasoning upon these ascertained facts, the idea occurred to two eminent members of the profession, Dr. Simpsonof Edinburgh and Dr. Radford of Manchester in England, (and who, by the by, disputed the point of priority,) that a separation and abduction of the placenta, in cases particularly where this was centrally attached, would be the speediest means of bringing about a cessation of the haemorrhage. This plan has frequently been adopted of late years by both, and, they tell us, with a success which fully equals their expectations. Success- ful cases are also recorded by other practitioners who have adopted their views. Are the arguments sufficiently strong in support of this plan of pro- ceeding? This is a question which every man must decide for him- self, upon a careful review of the whole ground ; for it is certainly true that reasons may be adduced both for and against the validity of such a procedure. In Scotland and in England, where the gentlemen referred to severally reside, the profession appear to have taken sides, and many of the back numbers of the Lancet particularly, are crowded with communications on the subject. I shall not attempt to relate all that has been said on the one side and the other ; the reference I have given as to the sources of information, will be sufficient for those who feel any curiosity about the matter — I shall merely revert to this plan of Drs. Simpson and Radford, as one of the modes now adopted in the treatment of placenta praevia. The great object to be attained by the prior delivery of the placen- ta, is the arrestation of the haemorrhage. To this conclusion no theo- retical reasoning would perhaps have led us. The occurrence of the fact itself was absolutely necessary to induce a positive belief in its existence. We are told by many who have adopted the practice that it is true, and I for one am willing to trust their authority, having no personal experience in the matter. The fact being established, it is not perha.ps very difficult to find a satisfactory explanation. When a separation of the placenta takes place, the flooding must proceed from the large uterine vessels, the mouths of which are thus exposed ; and as the womb cannot take on its tonic contraction so long as its contents are unexpelled, the haemorrhage will necessarily conti- nue. If, however, the membranes be ruptured and the waters evacuat- ed, and in addition to this the placenta be extracted, uterine contrac- tion will supervene to a degree sufficient to check materially, if not wholly to arrest the flow of blood. With this end accomplished, al- though the life of the child is almost inevitably sacrificed, turning need not be resorted to unless there may chance to be a faulty presentation of the foetus. Such then is the plan of Drs. Simpson and Radford, which, although it destroys, as I have just observed, the life of the child in a very large 8 HAXALL ON UTERINE HEMORRHAGE. majority of instances, yet has the advantage of very frequently saving that of the mother. By a comparison of the two modes of practice, can we only arrive at positive conclusions with respect to the value of. each. If we adopt the generally received plan of proceeding, the life of the infant is sometimes, though not very often, saved, while that of the mother is too frequently sacrificed. By the method newly recom- mended, and which I have here endeavored to detail, a large per cent- age in the saving of maternal life is found to result; and if the rule, universally I believe adopted by the profession, that the life of the mother is of more value than that of the child, is still to hold good, the weight of argument would seem to incline to the practice of the prior removal of the placenta. The manner of effecting this, we are told, is simple enough. When the os uteri is sufficiently dilated, the finger is to be passed between the uterine walls and the adherent placenta, and by gliding it around its whole circumference, the connection is thus severed. When this part of the process is finished, with the hand above the placenta, it is gent- ly pushed down into the vagina, from whence it may easily be removed. I shall now say a few words in relation to those cases of haemorr- hage which supervene subsequent to parturition. This is a condition also of very great danger to the woman, and it has fallen to my lot to witness several severe cases of this variety of haemorrhage. I have seen the patient delivered without one disagreeable symptom manifest- ing itself, and when all bid fair speedily and safely to terminate. Soon, I have seen her complain of a sensation of sinking or faintness ; her lips become blanched, her ears ringing with disagreeable sounds, and her vision darkened and obscured. Her pulse hurries on with a fearful rapidity and with diminished force, until by and by it is no longer to be felt; a clammy moisture bedews the surface; the respira- tion is deep, prolonged or gasping; vomiting frequently ensues — and muttering delirium,, with wild and senseless tossing of the arms, but add still gloomier features to the horrors of the scene. When we turn our attention to the condition of the uterus, we shall find that it has failed to return to that state of tonic contraction which it ought to have assumed, and that haemorrhage to a greater or less amount, has been the result. Inertia of the womb, if the placenta shall not have been detached in whole or in part, will not be productive of haemorrhage, because the large uterine and placental vessels still remain unexposed ; and I have seen this condition of things continue for hours. When, however, the placenta shall be wholly or partially separated, the interposition of art cannot be long delayed ; every effort must at once be put into requisition for the purpose of producing contraction of the womb ; for until this shall have been attained, it is idle to expect a cessation of the haemorrhage ; it is the only condition upon which we can rest the security of the patient; and fortunately for her, several available means are at the command of the accoucheur. Active friction should without dela}'' be made over the region of the uterus, and ergot promptly and largely administered. Cold applications may also be resorted to ; and if these remedies fail to produce contraction of the womb, and consequent ex- HAXALL ON UTERINE HEMORRHAGE. iJ pulsion of the secunclines, the hand should without hesitation be intro- duced, and the placenta removed. When this end is accomplished, the uterus almost always returns to its state of contraction. But there is another and more serious complication than the one to which reference has just been given ; it is, the continuation of haemorr- hage after the extraction of the placenta. In this case the flooding may exist under two very different circumstances ; it is either appa- rent, deluging the patient's bed with blood, or it. may be concealed ; in which latter event it is retained within the womb. In the case where the blood is retained, all the rational signs of haemorrhage, if I may so speak, and which have been named above, may take place ; and when we come to examine the condition of the womb we shall find it largely distended, reaching in some cases even above the unbilicus. The obstruction to the exit of blood is produced either by a contraction of the os tincae or by the presence of a pretty firm clot. So soon as this is removed, or the contraction of the os overcome, the blood pours out with a fearful rush. Contraction of the uterus very generally succeeds to this; and while perhaps we may be congratulating ourselves with the hope that it will remain permanent, the lapse of a few moments will convince us that we have again to contend with the same disagreeable symptoms. This alternate con- traction and dilatation of the uterus, I have witnessed in one case as many as three times ; and it is not difficult to believe that under such circumstances the patient is often brought to the brink of the grave. The first thing to be done, when haemorrhage supervenes, whether apparent or concealed, is to proceed diligently with frictions over the region of the womb. If this should not cause it to contract, the appli- cation of cold may be resorted to, and the plan recommended by Dr. Gooch will often be found very available. Cold water should be poured from a pitcher or teapot elevated some foot or more above the body of the patient. Injections of cold water into the womb have also been advised, but having succeeded by other means, I have never employed them. Velpeau's plan of placing a mustard plaster between the sca- pulae, the action of which he candidly confesses he does not under- stand, but as to the efficacy of which he speaks with much certainty, may also be tried ; nor should the administration of ergot be omitted. The application of the child to the breast should not be disregarded, for the sympathy existing between the mammae and the uterus will not unfrequently ensure its contraction. Failing in all these measures, the practitioner should boldly but cautiously pass his hand within the uterus, and having turned out all the clots, with the other hand placed upon the abdomen, and thus embracing as it were this organ between the two, he should institute such an amount of irritation as to produce its contraction. While this is taking place he will find his hand gra- dually pushed from its position within the womb, until it finally reaches the vagina. A bandage reaching from pubes to sternum should be ap- plied, taking care to place a thick and firm compress immediately over the womb. In the case now under consideration, the tampon is not only useless but even objectionable; for it would be the means of converting an 10 THWEATT ON DIARRHCEA AND DYSENTERY. open into a concealed haemorrhage. In conclusion, I will merely re- mark, that active stimulants are frequently demanded during the pro- gress of the treatment; and when the haemorrhage has ceased and the s}Tstem re-acted, a bland and nutritious diet will become necessan7. On the use of the Nitrate of Silver in certain forms of Dysentery in Adults and Diarrhoea in Children, with cases and remarJcs. BY J. J. THWEATT, M. D., PETERSBURG, VA. My object in this paper is to call the especial attention of the profes- sion to the therapeutic action of the nitrate of silver in certain patho- logical conditions of the intestinal mucous membrane. The experi- ments that have been made with this medicine on the continent of Eu- rope, conclusively shew that its action on the mucous membranes generally is of a particular or specific character. The attention of many able pathologists has been directed to the object of ascertaining the precise morbid states, to the removal of which it should be ad- ministered. Upon this point, there is much diversity of opinion ; with some, the existence of the inflammatory element is no contra-indicaiion to its use ; while others maintain, that, when inflammation is present, it should be withheld or used with extreme caution. My experience with this agent, which has been pretty extensive, convinces me, that in diseases of the mucous membranes, where the inflammatory action seems high, the employment of the nitrate of silver is attended with prejudicial effects ; and I am moreover convinced, after an attentive- perusal of the authors who have written upon the subject, that much of this contrariety of sentiment is to be attributed to the confounding of the terms of irritation and inflammation. In my opinion there is a marked distinction between the two pathological conditions, and that this distinction should be kept prominently in view b}r the practitioner who contemplates employing the nitrate of silver. In the one state he will find its action eminently curative, in the other highly injurious. In the one state the nitrate of silver acts like a charm, removing everv symptom — in the other, it acts like a poison, aggravating all of the symptoms ; in the one it is a placebo — in the other it is an active irri- tant. With these general remarks upon the pathological action of the ni- trate of silver, we will proceed to its application in dysentery and di- arrhoea of marked forms. During the summer months, and particularly after heavy rains, d}rs- entery in some form prevails to considerable extent in the suburbs of our towns and the surrounding counties. In the years 1846-7-9, 1 was called to attend many cases of this disease ; one form, from its fre- quency and obstinacy, attracted particularly my attention. The follow- ing phenomena characterized it : The person would be seized, after an exposure to the heat of the sun, with an intense desire to have an eva- cuation, accompanied with a disagreeable itching about the anal region ; on going to stool and passing a small quantity of mucus, he would ex- perience relief; this however was but momentary, for in about half an THWEATT ON DIARRHCEA AND DYSENTERY. 11 hour, he would be again seized with the same symptoms. The con- stitution at first is but slightly affected. There is no fever — pulse calm — skin in a perspirable condition — no thirst — no headache — the upper portion of the digestive organs remaining in their normal condi- tion— no anorexia — no nausea — no enlargement of liver or spleen — no tenderness on pressure ; the patients complaining of nothing but great tenesmus, itching and soreness around the anus. The quantity of the discharge rarely exceeded half an ounce — often no more than a drachm was evacuated at a time. The discharge consisted entirely of mucous, tinged more or less with blood. The above symptoms would continue, with very little diminution or aggravation, for some four or five days, when a new train of phenomena would make its appearance. The patient complained of great debility, want of sleep and appetite — the mind became irritable and fretful, pulse more excitable, especially as night approached ; in some cases anemia came on — still there was no pain in the bowels except in the lower portion of the rectum, about an inch or two inches from the anus. The pain in this part was in some cases excruciating, particularly on examination with the fingers : the soreness around the anus was a great annoyance — the evacuations would remain the same, only increased in frequency. I have seen the patient go to stool twenty to thirty times during a day, and the dis- charges all put together would not amount to/our ounces. When first called to treat this affection, I employed the usual remedies, calomel and opium, gentle laxatives, anodyne injections and fomentations, leeches to the perineum — in some cases mercury was carried as far as ptyalism, in conjunction with flying blisters over the abdomen. The result of this treatment was unsatisfactory ; a mitigation of the symp- toms would follow, and sometimes the disease appeared entirely sub- dued, but in a short time all the symptoms would return ; for instance, the calomel would frequently bring copious bilious passages, and after the lapse of five or six hours, the same inclination to go to stool, fol- loweel by the same discharge, would ensue. The anodyne injections and fomentations would produce their grateful and soothing effects, but in a few hours their pleasing results would disappear; no benefit was derived in any case from the application of leeches. The treatment proving so unsatisfactory, and the seat of the disease being evidently limited to the lower portion of the rectum, I came to the conclusion to direct my treatment to that point, and abandon all internal remedies except the mildest laxatives. The high encomiums which had been bestowed upon the nitrate of silver by continental writers, induced me to try its effects in this disease. I commenced by throwing up the rectum every three or four hours, two ounces of a so- lution containing five grains of the nitrate of silver to an ounce of dis- tilled water, adding a few drops of the tincture of opium. The first case in which I employed this treatment yielded in a few days. The treatment was fully carried out in all of the subsequent cases, and with the most beneficial results ; in a few cases the dose was increased to ten grains, but generally five grains to the ounce was of sufficient strength. I have selected the following case to illustrate the treatment : August, 1848, Mr. C, aged 25, of a strong constitution, general 12 THWEATT ON DIARRHCEA AND DYSENTERY. health good, after exposure to the heat of the sun, was seized about six o'clock in the afternoon with a great inclination to go to stool, ac- companied with itching about the anus — on going to stool, he would evacuate a small quantity of mucus mixed with blood, which afforded relief; the inclination gradually increased, so that from six o'clock in the afternoon to nine in the morning he had been to stool twenty or thirty times. At nine o'clock I found him in the following condition : complaining of no pain, none was felt on pressure, skin moist, pulse slow and moderately full, tongue broad, moist, with a whitish coating, no derangement of the cerebal or digestive organs. On examination of the rectum by the introduction of the finger, he complained of pain, extending about two inches up the intestine ; the parts around the anus were swollen and acutely sensible to the touch. On inspection of the evacuations passed during the night, they were found to consist of mucous, slightly tinged with blood. Had two discharges while pre- sent, of the same kind, about a drachm at each evacuation, complains of itching around the anus — says the desire to have an evacuation re- turns every fifteen minutes ; prescribed the following enema : & Argenti. Nitrat. gr xxx Pul. Gum Arab. 3 j Tinct. Opii. gtts xij Aq. Distill. 1 vj M Fiat enema. Two ounces to be thrown up the rectum every three hours — barley water for diet and drink — cold applications to the anus. Saw him again in six hours — had only three discharges — taken two injections ; says he feels much better — the inclination to go to stool diminished — ordered him a dose of oil with ten drops of the tinct. of opium. After the operation of the castor oil, to give an enema, and repeat it every three hours if necessary ; continue the cold applications ; same diet. Saw him again at 9 o'clock in the morning. Had slept well ; the oil had opei'ated twice, bringing faecal discharges ; used one injection ; had only one mucous and bloody passage. The tenesmus had almost disap- peared. Says he feels entirely relieved. Ordered an enema ; chicken water. Saw him in the afternoon. Had no evacuations — doing well in every particular. Left directions to use an enema, if the disease should return. Saw him again on the third day of his attack ; found him entirely relieved of every symptom of the disease, except sore- ness around the anus ; directed cold applications to be continued, and ceased my attendance, the cure being perfect. Remarks. — We could cite many similar cases, but this one is suffi- cient to shew the nature of the disease, and its proper treatment. The question now occurs, "What is the pathology of this affection ? Is it an inflammation ? We must reply in the negative. There was no symptoms which usually attend the inflammatory action; and the treat- ment, which generally subdues inflammation, was nugatory and some- times aggravated the symptoms. The disease appeared to consist in THWEATT ON DIARRHOEA AND DYSENTERY, 13 an irritation of the follicles of the mucous membrane of the rectum, attended with an undue secretory action. The action of the nitrate of silver in the case cited was that of a sedative ; it subdued the irrita- tion, arrested the undue secretion, and restored the parts to their nor- mal condition. Diarrhcea.— The nitrate of silver has been lauded by many emi- nent physicians as a remedy in this disease ; but I think they have failed to point out clearly the cases in which it is most applicable. It is admitted, that diarrhcea is dependent on a variety of causes for its production- — its anatomical lesions are various and diversified in their character; its therapeutics must consequently be of a diversified cha- racter. In our climate a peculiar form of this disease is to be met with during the summer months ; it makes its appearance without pre- monition. The attention of parents or nurse is first excited by the frequent and sometimes copious evacuations — the physician is sent for — he finds no heat of skin, or head, or mouth, or abdomen ; no sick , stomach or vomiting — pulse calm and quiet — tongue clean and moist ? the child is apparently in excellent health- — its appetite is good — his sleep undisturbed, except by the passages. This state of things is however of short duration. The constitution becomes affected ; the child gets weaker and weaker — loses flesh- — instead of pursuing its usual gambols, is disposed to lie down — it becomes fretful — the exter- nal features undergo a marked change — the countenance is pale — skin corrugated and of low temperature — the pulse small and quick — ■ tongue contracted, but still free from fur — appetite fails — the secretions from the bowels become more and more frequent, and if not soon ar- rested, death ensues. In the dissections which we have made of this form of diarrhoea, nothing was discovered but a slight congestion of the mucous membrane of the small intestines ; no traces of inflamma- tory action were detected. The character of the evacuations is various, both with regard to quantity and quality ; in some they are natural, only more abundant and frequent, and less consistent ; in others they are small, mixed with mucous and of strong bilious appearance — in some green, in others dark or whitish. We have found no remedy so beneficial in this form of the disease as the nitrate of silver, as the following cases will shew : June 8th, 184S. W., set. 19 months, has been subject to the bowel complaint for two weeks — 'much debilitated from the disease — coun- tenance pale — skin cool — tongue natural — pulse slightly irritable — ap- petite bad — no pain on pressure — no cerebral derangement, but is very restless and peevish. The discharges from the bowels were of a deep yellow color — no mucous or blood could be discovered. Prescribed a warm bath and a teaspoonful of the following mixture every four hours ; Argent. Nitrat. gr ij Aq. Gummi. 1 iij Tinct. Opii. gtts xij M Fiat mist. 14 THWEATT ON DIARRHCEA AND DYSENTERY". June 7. Has had three operations from the bowels of more con- sistency, color more natural — appetite improved — had rested well — continued the mixture. June 8. Had only one evacuation in twelve hours — that one of a healthy appearance. Looks better, had taken heartily of nourishment : suspended the mixture. June 9. Had no return of the diarrhoea, condition improved in every respect. The child recovered without further medical aid. June 18. Edward, infant, aet. 9 months, had diarrhoea for four or five days. Had taken calomel, Dover's powders, oil and chalk mixture. The effects of these medicines had been only temporary. The dis- charges would cease for a day and then return. When I saw the child it was free from fever, lively and playful, gums not swollen, having five or six passages during the day. They were green and slightly mixed with mucous. The abdominal perietes soft and flexible. No pain or sensibility on pressure. Tongue natural — no vomiting ; ordered the following mixture : Argenti. Nitrat. gr j Pulv. Gum. Arab. 3 j Tinct. Opii. gtts vj Aq. Distill. 1 iij Fiat mist. Teaspoonful every three hours. Saw the child in the afternoon. Had taken three teaspoonsful of the mixture. No passage after the first dose of the mixture. No fever ; had been sleeping. Ordered a tepid bath at bed time and a teaspoon- ful of the mixture and one early in the morning. June 19. No passage through the night — had slept well — was playful and entirely free from fever. Ordered a dose of oil and a tea- spoonful of the mixture after the operation of the oil, to be repeated every four hours if necessary. June 20. Had rested well during the nioht. No fever. One health v operation from the oil. Suspended the medicine, with directions to resume it if the disease returned. Saw the child on the 23rd. Had taken only one teaspoonful of the mixture. The passages were healthy. Stopped all medicine. The child enjoyed excellent health. Remarks. — The action of the nitrate in these cases was prompt and efficient. It soothed the irritation of the mucous membrane ; gave tone to the general system — and acted as a sedative and tonic astrin- gent. The doses were small, from iV to aV of a grain. It has been recommended in larger doses. I will add that no doubt larger doses would be borne with safety. lindsly's cases of mumps. 15 Tivo Cases of Mumps, with Metastasis to the Brain, both terminating fatally . — By Harvey Lindsly, M. D., late Professor of Pathology and Prac- tice of Medicine in the Columbian College, honorary member of the Rhode Island Medical Society, the New Jersey Historical Society, <8fc. Cases of mumps with determination to the brain are so exceedingly rare that I do not recollect to have seen or read of more than three besides those referred to at the head of this article. Most of our popu- lar writers on the practice of medicine, though men of extensive ex- perience, have evidently never seen a case, while they still speak of it as of occasional occurrence. This is the fact with Good, Eberle, Wood, Dewees, Mcintosh, Watson, Tweedie, &c. ; and indeed the only author that now occurs to me, who speaks of this complication as having come under his own observation, is Dr. Dickson of Charleston, in his able and interesting work published a few years since. In January 1849, a son of Gen. W., who at the time was a student of medicine and attending the lectures of the medical school in this city, was attacked with the mumps, and after a few days' illness died, as I was informed, from metastasis of the disease to the brain. I can- not give the particulars of this case, as the patient was not under my professional care. On the 1st day of February following, about a week after the death of this young man, I was requested to see his brother, (setat. 20,) a student of Princeton college, who was at home on a short visit to his friends. I found him laboring under a well de- veloped attack of mumps of the left side, the gland considerably swol- len and with some fever, though on the whole suffering but slightly, and feeling, as he remarked, very comfortable. The disease seemed to be taking its usual course, and if it had not been for the recent death in the family, would have excited little interest or observation. As it was, however, his friends felt some anxiety, and I was induced to attend the case more carefully than I should have thought necessary under ordinary circumstances. As precautionary measures, I directed pretty active purgatives, followed by diaphoretics, hot pediluvia, warm flannel to the swollen gland, &c, and watched very closely for any in- dications of disease of the brain. I could detect nothing of the sort however, and until the fifth day everything seemed to promise a fa- vorable termination. I examined my patient carefully twice a day, with reference to the condition of the testicles as well as the brain — but there was no apparent disturbance of the functions of the one, and no enlargement of the other. He was cheerful, slept naturally, and felt confident of a speedy recovery. Upon examining him, however, on the morning of the fifth day, my apprehensions were excited by finding that he was laboring under -priapism. I dreaded this symptom the more, as the disease seemed now to be taking the same turn that proved fatal in his brother's case. He was immediately ordered to be leeched freely at the base of the brain — a blister was applied to the nape of the neck, purgatives given and an active general antiphlogistic treatment adopted. At the same time additional professional advice was obtained. During the whole of this day, however, the priapism was the only indication we could detect of diseased brain. 16 PEEBLES ON THOMPSONIANISM. On the next morning we were informed that he had been laboring under delirium the greater part of the night — had been restless and suffered much. These symptoms continued to increase in violence, convulsions came on, and in a few hours death closed the scene on the sixth day of the disease and the second after the appearance of the priapism. A careful examination of the brain was made thirty hours after death, when decided marks of inflammation and congestion were found in the cerebellum, but none in the cerebrum. Washington, Nov. 29th, 1850. The Rise and Progress of Thomj)sonia?iism. BY J. F. PEEBLES, M. D. This is an indigenous production. Perhaps, on that account, we ought to approach it in a friendly spirit. Ours has been said to be *' the greatest people in creation." The writer is the last person in the world to underrate the national supremacy : but candor is an indis- pensable attribute of the historian. This compels us, in the very out- set, to declare that this, which is the most prominent specimen of our native medical delusions, proves that the attempts of our people in that line have, as yet, been awkward, bungling and extremely unre- fined. The right materials seem not to exist with us yet for excellence in these matters. How coarse and crude appears this torturing prac- tice of medicine, when compared with the refined idealisms of home- opathy and mesmerism ; even before the less elegant system of hydro- pathy, it sinks into insignificance — it has no protot37pe in the old world. It embodies a spirit which has no existence there, that of our restless, dauntless, active, western backwoodsmen, who even judge of their "physic" by the amount of labor it is capable of performing. It sprung from the necessities of this part of our population, and it em- bodies that which comports with the characteristics of their minds. — The man who is ripe for a belief in Thompsonianism would turn up his nose at homeopathy. The true nationality of its production is elucidated by its course ; it tends westward with the pioneers, leaving the east, where men, living upon their wealth and retired from business, have the time to be invalids, for the prevalence of the more luxurious and aristocratic systems of homeopathy and its kindred spirits. Samuel Thompson, its founder, was born in the year 1769, in the town of Alstead, New Hampshire. His parents were among the first who settled in that region, then a wilderness ; they were poor, and supported themselves by the labor of their hands. The young Sa- muel, therefore, became early acquainted with manual labor ; and he tells us himself, in more than one place, that he had no fondness for it. Whatever genius he might have possessed, was certainly not soon discovered by his hard-working father, who, despite his aversion to it, and a lameness which much incapacitated him, kept his son steadily employed on the farm. This parental sternness, as has been often the case, was the making of the boy. It fixed his aversion to labor so in- PEEBLES ON THOMPSONIANISM. 17 delibly, that he early began to turn about that he might devise some means of living without it. An opportunity was not long in present- ing itself. Being totally unprovided with physieians, the necessities of the rude settlers, scattered through that wild country, often led them to seek medical aid from any source it was profFered. In this way a sort of rude practice sprung up in the hands of old women and others, whose medicaments were gathered from the fields. Young Thomp- son was not slow to discover the necessities of the community, and with an eye always toward an escape from the drudgery of labor, he early joined these drug-gathering parties, and eagerly turned his atten- tion to the simple practice of the neighborhood. The expedient was a successful one ; his knowledge of the rude medicaments in common use became so perfect, that when only 8 years old he was dubbed " Doctor " by his neighbors, and was often called on to decide upon the properties of medicinal plants. His acquirements, and the general belief in his great medical pro- mise, finally overcame the sternness of his father, and he tells us, that provided his services could have been spared from the farm, and had his education, which as yet consisted of only one month's schooling, been sufficient, he would, in his 16th year, have been sent to learn medicine under a certain root doctor of Westmoreland. This step, had it been carried out, might have been unfortunate for his subsequent celebrity as a doctor ; and if so, it would certainly have been fortunate for many a poor victim to his crude and remorseless system of practice. We have no idea of the medical knowledge of the root doctor in question, but we hold that, were he possessed of any experience in dis- ease, or any information about remedies, it would have been sufficient to have enabled him speedily to instil that in his pupil's mind, which would have thoroughly disgusted him with the career he was about entering upon. Our meaning can best be illustrated by a veritable in- cident. We once heard of a groom, who fancied he had a natural turn for surgery. After performing with the rudest implements, many mi- nor operations, a woman was finally brought him with a cancerous breast, which the most distinguished surgeons had declined amputat- ing, because the disease had extended itself to the glands of the axilla in such a manner, as to render the operation, not only useless, but immediately dangerous. It was a mere trifle to our groom. He re- moved it in a jiffy. It is true, the axillary artery was wounded and the haemorrhage was terrific ; yet, nothing daunted, he coolly seized the wounded vessels with a pair of ordinary pinchers well heated, and miracuously stopped the bleeding. The wound healed kindly, and the woman was soon sent home as well. The result of this feat was the formation of a purse, by some be- nevolent persons, who, determining that such natural abilities should not be lost to the world, had resolved to afford the operator a regular medical education. Before his term was half out at the university, however, he returned home and quietly resumed his stable duties. — When asked for an explanation of this conduct, his reply was, that he bad become so shocked at his former foolhardiness, by what he had learned of medicine, that he was deterred from its further prosecution- 2 18 PEEBLES ON THOMPSONIANTSM. That he then knew the danger of the knife, and henceforward, those who chose it might become surgeons; but as for himself, he never meant again to remove even a wart from the human body. Denied even the small chance of having the conceit taken out of him, which the root doctor might have afforded, our hero, we find, was left to pur- sue his labors on the farm and his medical studies at the same time. Without learning, without books, without a guide or example, it ap- pears, of any kind, this rude child of genius boldly knocked at the door of nature's great storehouse of knowledge, and he fancied that it was opened unto him. His history is a curious and not uninstructive ex- ample of the study of medicine denovo, without reference to what was hitherto known respecting it, occurring in our own times. A contrast of his method with that of the most primitive medical enquirers of which we have any account, certainly proves an advance in the human mind, which is exceedingly interesting. Instead of ap- pealing to the gods or to the heavenly bodies ; instead of selecting remedies as was done b}r the earliest medical enquirers, according to a fancy, dictated by the shape, color, brillancy of substances, Thomp- son very philosophically, certainly, appealed directly to nature. He tasted and tried for himself; he experimented on his playmates and fellow-laborers with any thing that came in his way. We approve of this method of enquiry, and when we have said that, we have said all we can say in the praise of our hero. The great storehouse of nature had been too sedulously and tho- roughly examined by men qualified for the work by the learning of ages, to leave any thing to be culled by so crude and ignorant an ob- server as Thompson. Yet, for all this, we can sjmipatbise with his belief in the originality of many of his discoveries. How was he, for instance, to know that the lobelia had been long known and used by physicians, when he was altogether unlettered had never seen a me- dical work, and had no acquaintance, with any man having any preten- sions to medical knowledge. The maintenance of this belief, when he was told better, is exactly what might have been expected of one so ignorant and uncultivated in every thing necessary to an enlighten- ed and civil man. Though utterly useless to science, the labors of Thompson brought him rich results in the way of conceit and self- sufficiency. He soon began to look upon himself as a favored emissary of Heaven, sent to snatch his fellow-creatures from the clutches of the murderous faculty. Taking his own statements as authority, the man seems to have had but slight grounds for such a belief. The views which he took of disease would disgrace an enlightened New Zealander. We mar- vel how even he could have held such doctrines. It appears to us that the very powers of thought required to frame a theory at all of disease, ought to have ensured him against such manifest absurdities. He looked upon the human body as a great pot, to be boiled or refrigerated at pleasure. Disease he held to be something, endowed with a sort of life, which could only be killed out of the body by his " courses." To destroy this mis- chievous stranger was the end of his medication. He puked, steamed and stimulated ; that not answering, he puked, steamed and stimulated PEEBLES ON THOMPSONIANISM. 19 again and again. His method of practice was exceedingly simple ; it was as plain as the building up and the putting out of a fire. He made no allowances for the vital properties of the body, but acted on it as though it were but inorganic matter. Heat, every one knows, vo- latilizes water : taking the hint, Thompson cured dropsy through an evaporation of the effusion, by raising the internal and external heat of the body. Such crudities fail to excite even our derision, and we turn from the further consideration of his mere theories with feelings of pit3r, blended with amazement, that such notions could have ever found advocates among a civilized people. Having fixed upon his " courses," to be employed alike in the treatment of all diseases, he set out on his great mission. It is due to the man to state that he prosecuted his plans with admirable energy. Indeed it is difficult to recognize the possession of so much perseverance associated in the same individual with so little intelligence. One would have supposed, at least, that the latter would gradually have been supplied, to some extent, by the exercise of the former quality. Not so with Dr. Thompson — he was too wise to learn; and he gained nothing by the contact with the world. His ignorance and self-sufficiencv encrusted O J him too securely to admit of the penetration of a single ray of know- ledge. He rivalled Paracelsus in the importance in which he held him- self: the professor of the much longed for philosopher's stone could not have been more arrogant. The brass of the man was inconceiv- able. Not content to preach his doctrines into the ears of the unenlight- ened in medicine, he bearded the lion in his very den. He -tells us that he called to have a conversation on medicine with Dr. Rush, and speaks of an interview with the elegant and accomplished Prof. Bar- ton of Philadelphia. The smiles of physicians at his blunders he construed into envy of his success, and he seemed to be in perpetual trouble lest some one would seize and appropriate his discoveries. He carried the war into the enemy's country, and probably owed much of his popularity among the unenlightened to his attacks upon the faculty. It was lis that ori- ginated the prejudice against mineral medicines, still deeply rooted among the ignorant, and set the popular current in favor of vegetable or botanic remedies. Such was the character of Dr. Thompson. We dismiss its consideration with the assertion, that so much ignorance, self-conceit and daring energy were probably never before associated together in the same individual. After many }rears spent in journeying about from place to place, healing the sick, the results of his medical investigations and dicove- ries, Dr. Thompson, to protect himself, as he says in his narrative from being robbed of all merit and emolument, ultimately embodied in a book, which he sold under the protection of a patent. His first patent, it appears from his narrative, was obtained in 1813. The early introduction of the system was attended with many annoyances. Dr. Thompson fairly suffered martyrdom for his strong faith in his discove- ries. We read in his book constantly of severe trials, arising chiefly from the ingratitude of his patients, the persecutions of the faculty, the faithlessness of his agents, and the general wickedness of mankind, 20 PEEBLES ON THOMPSONIANISM. from the judges on the bench, who sat on his causes, down to the old women who had acted as nurses to his patients. His whole life, as he has most touchingly given it, is a satire on humanity: an instructive commentary on the injustice of the world ; marked, however, by the pleasing contrast afforded by his own meek endurance of evil, and steady adherence to the interests of his fellow-men. The Doctor seems to have encountered a perfect shoal of swindlers ; to have submitted his bantling to the world in most evil limes ; hence, he got but slight gains for all his troubles — received but little remuneration for his bene- fits to mankind. His agents ran off, however, with immense sums obtained from the sale of rights, which, first to last, must have yielded a vast deal of money. The new doctrine gradually spread from New Hampshire into other states. Next to that giving it birth, Ohio, from the first, ap- pears to have afforded it the warmest reception. It was disseminated with the greatest zeal. The manner of its circulation was like that of a patented machine. Agents, armed with set phrases against the use of mineral poisons, and in favor of vegetable remedies, peddled the books through the country, and sold the right to their use in practice at twenty dollars per right. It steadily spread on, until it pervaded the whole country, including the Canadas. Every neighborhood was invaded, and in every neighborhood one or more individuals were to be met with, possessed of the requisite turn of mind necessary to constitute a Thompsonian doctor. An observer might soon have learnt to point out the individual in any given place likely to adopt the new calling. The varieties of the species are great, }7et admitting of classification. Your embryo Thompsonian doctor is considered in his neighborhood a smart man for his chance, although }Tet he has never been good for much. He is constantly astonishing his neighbors by his versatile mind. He is much wanting in veneration ; hence, old and established usages of every sort are frowned at by him. There is nothing which he be- lieves he cannot do; hence he is ever ready to attempt aiyvthing that comes to hand. He has no particular trade or business, yet he follows any that he fancies. Ten to one if he is not set up in some intricate trade, as watch-making, which he has never learnt. If not so, he as- pires higher. He may deal a little in law7 — generally he is only a preacher — in every thing he is essentially by nature a quack and pre- tender. These are the men who readily take up this practice of medicine, making their neighborhoods ring awhile with their exploits, causing the old women to gape and wonder at the canker ejected, by the emetic weed, from stomachs hitherto held innocent of such abominations. These are the men who deer}7 the faculty, who shudder at mineral remedies, and who see health alone in the vegetable kingdom. One such was asked in our presence of what was calomel made? Of cop- per and brass, was his confident reply, doubtlessty deriving the opinion from a fancied analogy between that ''awful" poison and the vene- mous look of the rust of these metals. It took time — but, as we have said, the new practice has pervaded the whole country. We suppose fifty years must have elapsed from PEEBLES ON THOMPSONIANISM. 21 its first promulgation before it became so generally diffused. Not only in its results, but in the manner of its invasion, does its progress resemble that of the cholera. It comes, and after a time departs; its residence in all places is temporary, and its return only at long intervals. After sweeping through a neighborhood, it will depart ; years after, when the memory of its freaks has become dimmed in the recollection of" the survivors, it will suddenly re-appear and vehemently assert its claims to popular favor. Although partly, it is not altogether in this way that it has been kept alive. Samuel Thompson, it seems to us, was honest in his belief about this practice. This is demonstrated by the artless manner he unfolded his doctrines. It is evident he meant them to rest exclusively on their own merits. He believed them himself, and he expected them to carry conviction to others. This was a frail reliance ; the creed had within itself the elements of its own speedy destruction. We affirm that, had its original spirit been maintained, had not its con- trol passed in a measure out of his hands, the system would have died with its founder. Long before his death, Thompson complained bitterly of the innovations of his disciples. These, more artful and long-sighted than himself, watched the popular mind. Money-making was their object; hence, to keep the delusion triumphant, they steadily propped it wherever it appeared to be giving way. In this way only has it been kept from sinking. In late years but few, if any, of the true breed are to be met with. Thompsonianism, as Samuel Thompson taught it, has long been dead ; but out of its ashes there has arisen recently a more dangerous, because more imposing and disingenuous sect. We have now the Eclectics. These pre- tend to combine the excellencies, without the obnoxious parts of both systems of medicine, the "regular" and the Thompsonian. This has led to a new swarm of specious quacks, which overspread the land. Cincinnati is their head-quarters ; from thence they emerge like lo- custs, to desolate the country. In many places they are now in the full tide of their prosperity. But they cannot last long; this medical monsoon will soon vanish ; then Thompsonianism will be forever dead. The system is completely worn out;' there is not enough of it left to hitch on another saving appendage. One word about the practical ope- ration of this system of medicine, and we are done with it. We have before alluded to the theories which guided Thompson in the applica- tion of his remedies. They are too absurd and ridiculous to be again referred to ; yet we candidly state that there was more in his proce- dures than he had the mind to appreciate. We mean that he was una- ble to perceive wherein his remedies were in certain cases salutary ; too ignorant to tell in what manner they might sometimes cut short an attack of disease. Need anything more be said to prove the utter recklessness and danger of this system of quackery? His remedies were powerful ; the;y produced the most violent and perturbating effects. In this way, in cases suitable, but limited in their number, their revo- lutionary tendencies might induce, although in a bungling and exceed- ingly uncertain manner, salutary changes. Applied without discrimi- nation, as it was in every disease, it could but lead constantly to the most criminal consequences. The people are slow to condemn 22 JONES' OPERATION FOR LOSS OF UNDER-LIP. their petted systems ; yet Samuel Thompson, for all that, was several times brought to the bar of justice to answer the charge of murder, too palpably committed to escape the observation of the bystanders. Un- like some other delusions, all his blunders and crude experiments upon his patients have added nothing to the stock of medical knowledge. He had but glimpses of very few and unimportant therapeutical truths, such as the influence of sweating as a curative means, which truths have been long unfolded in the most satisfactory manner, and are known to the merest tyro in medicine. He could do nothing, with all his bungling and torturing procedures, which medical men do not hourly do by safer, simpler and less disgusting means. He developed no principle in medical practice which had not been known for ages, whilst his therapeutical additions, which were new, were utterly value- less. The whole delusion was but an unmitigated evil. In addition to its direct evil tendencies, it has indirectly been the cause of much mischief. Its spirit, and the manner of its introduction, tended to make the people rebel against medical authority. It diffused a contempt of study and learning, and excited a prejudice in the popular mind against physicians as a privileged class, who held unjustly a monopoly, which they used to oppress the people. The vaunted success of its heroes favored the idea, that any one with twenty dollars in his pocket could be a better doctor than the most scientific and learned physician. It fostered and maintained all the existing popular errors about drugs, and even originated many that were new. We repeat, therefore, that the whole delusion, from the first to the last, has been an unmitigated evil, and one not at all likely to reflect credit upon the intelligence of our people. Deformity of the Mouth, caused by the use of Mercury, with loss of the greater portion of the Under-Lip, relieved by a Surgical Operation. BY WALTER F. JONES, M. D., OF PETERSBURG, VA. During the year 1845, 1 was requested to examine the case of a little boy from the county of Gloucester, Va., aged 14 years, who, it seems, had contracted a bilious remittent fever some six or seven years pre- viously, during the treatment of which, mercury had been employed by the attending physician, which resulted in the recovery of the pa- tient, followed by severe ptyalism and sloughing away of the under- lip. The patient exhibited the following appearance : The youth's ge- neral health seemed pretty good, but the deformity above referrred to consisted of the entire loss of the under-lip, save a very small teat- like remnant on the left side. The whole under surface, where the lip formerly adhered, from long-continued pressure, had become almost entirely cartilaginous, and was united firmly to the anterior portion of the inferior maxillary bone ; the tongue, with the sub-lingual glands, was much diseased and enlarged; also the sub-maxillary on one side. The patient could not articulate without the aid of a bandage, which served to prevent the tongue's protruding and the copious discharge JONES OPERATION FOR LOSS OF UNDER-LIP. 23 of saliva. This bandage had been worn for several years, and from its continued pressure, served still more to paralyze the muscles upon which it acted. His voice was reduced to an indistinct guttural sound. Food could only be taken over the bandage, and had to be forced back by the finger to the posterior dorsum of the tongue, the latter having partially lost the power of aiding in the art of deglutition. All the teeth in the lower jaw had been destroyed as far back as the second molar. A the subjoined. drawing from a cast of the original is exhibited in After the necessary preparatory treatment in the presence of Drs. Peebles and Spencer of our city, I commenced the following operation: It became necessary in the first place to remove the cartilaginous adhe- sion which had formed and which has been described above. An in- cision from left to right was made with the scalpel, including the rem- nant of the lip to the left down to the periosteum. The bone itself was found sound and healthy, judging from the condition of the latter membrane, although the alveolar processes had been absorbed. After removing that portion which seemed devoid of all vitality, the dissec- tion was continued entirely around the chin and clown to the perios- teum, and the operation for hare-lip was performed, all the substance gained from under the chin being previously pushed up. In order to prevent adhesion from taking place to the gum, a small portion of zinc, of proper form, suggested by the shape of the decayed alveola?, and to supply their deficiency, was applied and worn during the whole treatment. Of course there was little or no haemorrhage, as only small branches of the facial artery were divided, which required only a small 24 JONES' OPERATION FOR LOSS OF UNDER-LIP. twitch of the forceps to arrest the slight flow of blood. The bandage for fractured lower-jaw was then applied, which served to keep the substance under the chin in its desired position. After the operation the patient was comparatively comfortable, and only required an ano- dyne for the night, which was spent quietly. Nourishment was ad- ministered by means of a glass tube through an aperture afforded by the loss of an upper tooth. After the fourth da}* the bandage was re- moved, and the adhesion was already formed, needing only the appli- cation of a narrow strip of adhesive plaster between the sutures, and one below the second suture. The bandage was re-applied. It was ne- cessary to remove it every third or fourth day and adjust the zinc plate, if necessary. Our little patient continued well until about the fourth week, previously to which the adhesion had entirely formed, to all ap- pearances, and the needles had been removed. When about the com- mencement of the fifth week we observed a small dark spot which appeared immediately under the upper suture. In a few days a fever came on, and we began to fear sloughing ; but with close watching, nutritious diet mild tonics, and perfect rest, with an occasional ano- dyne, we began to see our little patient improve ; although the dark spot above alluded to continued to increase, leaving a narrow band between the upper extremities of the lip, and was not arrested until about the eighth week, notwithstanding the above general treatment and the oc- casional cautious application of lunar caustic. I may here add that the bandage was worn for several months, which afforded considerable comfort to the patient. Even at this stage he could speak quite dis- tinctly, and eat with comparative ease. The enlarged glands were greatly improved, and the tongue itself could be protruded with little or no inconvenience. The patient was allowed fresh air and nutritious diet ; and the opening on the lip was protected by a small portion of court plaster. After the expiration of six months from the first ope- ration his health had been entirely restored, and about the eigth month the second operation for hare-lip, employing only one suture, was per- formed, which in less than ten days had healed completely. It be- came necessary to apply a few false teeth upon a well formed artificial plate, corresponding with the deficient alveolae, which gave the lip its former natural appearance. In a few weeks he returned home entirely relieved from this distressing deformity. Drawing No. 2 will give a tolerably good idea of his appearance after the second operation.. BROWNE S ADDRESS. 25 [ We regret to send out such a caricature of the face as the second cut gives, but the lateness of the receipt of the cuts rendered it impossible to have a new one made. We hope an idea, at least, of the cure of the deformity will be given by- it and the description in the context. Editor.] An Address delivered before the Medical Society of Fredericksburg. BY WM. BROWNE, M. D., (PRESIDENT OF THE SOCIETY.) I congratulate you, gentlemen, upon having at last completed the organization of the "Medical Society of Fredericksburg and the ad- joining Counties." I hope in all our proceedings we shall be guided by a spirit of conciliation and forbearance, which alone can render our intercourse agreeable and our action beneficial to ourselves and useful to the profession. We shall be frequently called on to exercise this forbearance in our remarks and criticisms on the reports of cases and professional essays which may be read before the society. But the characters of our members, happily, area satisfactory guaranty, that, in all our discussions, they will exercise a due regard for the feelings of each other, and render this caution superfluous. On this occasion, it being our first meeting under our present organi- zation, I think it proper to submit a few remarks on one only of the numerous errors which have, for many years, been gradually extend- ing, and which, in this our day, prevail so generally. The error to 26 browne's address. which I allude is, the strong propensity to catch at and adopt novelties, both in theory and in practice, without allowing sufficient time to test their claims to confidence, by reason and experience. For the past half century, and especially during the last twenty years, revolution and progress have been stamped on every depart- ment and occupation of life. Even in the fixed sciences, the novel application of old and well-established principles has produced re- sults truly marvellous' and astounding. The general introduction of steam as a locomotive power has brought the inhabitants of our widely- extended country almost within the bounds of social intercourse, and by means of electricity we carry on friendly and business conversations, if such intercourse can properly be so called, with individuals thou- sands of miles from us. Schemes are also in progress, and will, in all likelihood, be ultimately accomplished, to bring the whole of Europe within conversational distance of us ; and it may be that some of the present generation may live to interchange greetings with their friends in England, France, Holland, German}^ and probably even in Rus- sia, in the space of a few short hours. Mutation and progress are also stamped on our profession, and it re- quires vigilant care and close application to study to keep pace with their rapid strides. Our profession, however, is not a fixed science, and there are but few principles belonging to it that can be considered as determined. Progress and change here, then, must be carefully watched, that they lead us not into error. Our profession deals with the lives of our fellow- men, and our errors lead to death. Let us be careful, therefore, to avoid being led astray by the specious represen- tations and unsound deductions of over-sanguine members of our pro- fession, which too often come from men of high professional reputation, and which are scattered throughout the world in medical periodicals. There is a strong tendency in the present day, in all classes of societyr, to catch at novelty, and to build up ingenious theories and s}7stems, on the foundation of a few isolated facts, and these by no means satisfactorily substantiated, but, in truth, too often assumed. Our profession is by no means exempt from this prevailing bias. From this source has arisen homeopathy, frydropathy, Thompsonianism and other kindred medical fictions, which have obtained many proselytes, even from the ranks of the profession, and which are yet extensively engaged in the work of death, not only abroad, but throughout our own country ; and not onl} has it given rise to systems professing to be based on pathological data, but it has resuscitated from the ruins of Iry-gone superstitions, the miracles of monkish charms and relics, Prince Hohenlohe's prayers, Mesmer's hallucinations, and many others equally repugnant to reason and to sound sense. At a more recent date the semblance of deadi has been paraded on the stage, and ether and chloroform, the agents in this counterfeit representation of the extinction of vitality, have been hailed as among the choicest gifts from Heaven, which were, if not to deprive disease of its mortality, at least to procure exemption from all physical suffering, and to wreath in smiles the countenance of the most timid and delicate during the painful throes of parturition, and, what have heretofore been considered the agonies of the gravest surgical browne's address. 27 operations, the very sight of which would cause the stoutest heart to tremble. That many have passed through this seeming death, with apparent impunity, we have abundant evidence, and I trust reliable, to shew ; that many, or indeed any, have been saved from real death, we have yet to learn. Sufficient time has not yet elapsed to enable us to learn whether dormant predispositions may not, in many instances, have been excited into life and vigor, which might have remained in- active for many years, if not for life, by the direct application of these potent agents to organs so important to life as the lungs. The evidence which has heretofore come to us has been, mostly, from the side of anaesthesia; an occasional lamentation, however, reaches us from the opposite quarter ; and late developments on the other side of the At- lantic are well calculated to excite alarm. The victims of this humane effort to mitigate suffering, have of late sadly increased, and the Lon- don Medical Gazette of the 7th of September 1S49, in a review of some treatises on anaesthesia in child-birth, closes with the following language, conveying a most solemn warning to all who use these agents to relieve the sufferings of labor : " The trial has been made ; the claims of chloroform and ether, as employed in midwifery, have been tested. The result has been, that the little advantage gained by the many, and the great detriment sus- tained by the few, fully confirm the statements made by Mr. Gream and others, as to the dangers attending the use of these agents — at the same time justifying and strengthening the voice of alarm; so that it is now almost as rare an occurrence to meet with an obstetric practi- tioner in London, who would venture to chloroformise a patient in la- bor, as it was common, a few months ago, to meet with those who were daily making trial of this new charm for the relief of suffering. After the perusal of Mr. G ream's pamphlet, now before us, we feel that they in whose hands the experiment has not resulted in sincere, but unavailing regrets, have much cause to be thankful." We have yet much to learn in relation to these important agents, before a correct opinion can be formed, either of the benefits or inju- ries which are likely to result from their use ; but the eagerness with which they were seized on, the extent to which their use has been carried, and the re-action which is already, to some extent, taking place, in regard to their introduction to general use, from the increased num- ber of fatal results, clearly point out the propriety of great caution in adopting novelties, and the necessity of carefully testing them before we give credence to the merits which their authors claim for them. The number of specifics introduced into practice of late years, b}*- medical men of distinguished stations — the facility with which they have been adopted, and the rapidity with which they have passed out of notice, have their origin in the same source; and it is mortifying to see the members of a profession, who claim pre-eminence on account of liberal education and careful mental culture, so often led into this prevailing error, when they have been so often misled and disap- pointed. But a few years since a gentleman who occupied a. high rank in the profession, and who was physician to one of the most extensive hospitals in London, proclaimed, as the results of his own personal 28 beowne's address. experience, that bi-carbonate of iron, in one or two drachm doses, amounted to a specific, almost, in tic doloroux. The same gentleman, about the same period, or perhaps a few years before, trumpeted fbtth kreosole as an infallible remedy in diabetes — one of the most fatal ma- ladies it has ever been my misfortune to treat. We all know with what avidity these remedies were adopted by many physicians in this country, particularly the first, as fortunately there occur more of those diseases in which iron was to prove specific, and how many feeble and delicate stomachs were crammed to overflowing with this earthy drug, luckily comparatively inert; and what has become of the anti- cipations so fondly cherished, that weapons were supplied to our hands, to disarm of their suffering and mortality, two at least of the enemies of our health, our comfort and our life? They have vanished into thin air, with the thousands which have preceded them; and, what is to be deplored, on account of distinguished talents, though sadly misapplied, their originator, still in search of some universal panacea, has wrecked his fame and reputation on the shoals of " Nickel and Mesmerism," and has become an exhibitor of the wonders of animal magnetism to the gaping nobles of England's metropolis in this the 1 9th century! How can we be surprised that individuals, uninstructed in our profession, and totally ignorant of our physical organization and of the functions and relative importance of the various and complicated organs of the human body, should seize with avidity on any of the nostrums, which in countless thousands are spread before them in newspapers, pam- phlets and almanacs, promising relief to "all the ills that flesh is heir to," and in too many instances recommended to public confidence by certificates from ministers of the Gospel, who "know not what they do" — and which, for the sake of suffering humanity, is deeply to be regretted — when members of the profession have so often been led to adopt medical prescriptions and plans of treatment in cases seriously involving life, on representations devoid of the necessary foundation to inspire judicious confidence? " Fashion in physic," has long been a reproach to the profession, from which, I regret to say, it is by no means exempt even at this day. How long it will remain so, must de- pend on the intelligence, the independence and honesty of its members. Nothing has a stronger tendency to increase and perpetuate such evils, as the introduction into the profession of young men of naturally sprightly talents, but of limited education, of little reading, and, of course, of defective judgment. Incapable of comprehending the che- mical changes which may take place from the introduction of incon- gruous materials into their prescriptions — unacquainted with the exten- sive and complex sympathies which exist between the various organs of the body, and the influence which remedies applied to one part, exercise through this medium on parts far removed from it, it is not to be wondered at that they should readily adopt remedies and modes of practice introduced to public notice by specious representations of their efficacy, and sustained by certificates of men of standing and reputation, but more ignorant of such matters even than themselves, and recommend and prescribe them with a confidence well calculated to beget a corresponding confidence in those to whom they are thus JOHNSON S CASE OF TETANUS. 29 recommended. Among such persons we often find individuals pos- sessed of considerable astuteness, who know well the necessity, and practice it too with no little success, of supplying, by address and a confident manner, the defects of education and the want of knowledge. It is to be lamented too, that the public is more gullible on medical subjects than on any others, and too often invites the deceptions that are practised on it. The formation of the " National Medical Association," with its va- rious ramifications extending throughout our country, by procuring a freer and fuller interchange of views, and bringing medical theories and facts to the test of close and strict examination and professional criticism, promises to do much towards ridding our profession of many of the evils and errors which encumber it. Its recommendations also to our public schools to raise the standard of medical education, which I am glad to see, has been favorably responded to by some of our leading institutions, will bring to its aid a most important adjunct in sustaining and forwarding the cause of humanity. I have thus briefly alluded to this tendency to delusion in our pro- fession as a caution to all of us, against yielding a too ready credence to new systems, new theories and novel facts, and to the adoption of new remedies, more especially if in undue quantities they act as poi- sons, without a strict and critical examination of the foundation upon which their claims to confidence rest. It is also highly important to avoid the opposite error, skepticism, which is equally, if not in a higher degree, injurious to the character and usefulness of our profession. In our search for what is true and useful, it would be well if both extremes could be avoided. Proceedings of the Medical Society of Virginia — November Meeting 1850. The society was called to order by Dr. R. W. Haxall, (president,) a large number of members and several visitors being present. After the disposal of some matters of business, there were presented letters of application for membership from several gentlemen, who were duly nominated. The subject of discussion for the evening, " Tetanus," was then called up by Dr. Carter P. Johnson, who said : In presenting the report of the following case to the society, I would remark, that tetanus, as well as other spasmodic diseases, assumes a higher degree of interest at this time, in consequence of the investi- gations at present in progress in regard to the functions of the nervous system. All writers agree in assigning the spinal marrow as the seat of tetanus ; or rather, in ascribing !o that portion of the nervous centres the emanation of the influence which is directly concerned in pro- ducing the spasmodic muscular aclion. The solution, therefore, of the iiutliology of this disease, must depend upon the proper compre- hension of the physiology of the spinal marrow. Besides the mere office of conducting impressions and influences to 30 Johnson's case of tetanus. and from the brain, the spinal marrow possesses the power of appre- ciating impressions conveyed to its grey matter, and of generating in- fluences which are conveyed from it by its exodic nerves, as was first proved by Procharca, and afterwards elaborately demonstrated by Marshall Hall. When in its normal state, an impression conveyed to the spinal marrow by an exodic nerve, causes an influence to be generated which is reflected back merely through the corresponding exodic nerve, pro- ducing a motion in the muscle to which that nerve is distributed ; but if the natural excitability of the spinal marrow be exalted, the same impression conveyed to it will be responded to by a considerable por- tion of the organ, and will be reflected back by a large number of exodic nerves, producing a corresponding muscular contraction. Now if, when the excitability of the spinal marrow is thus exalted, }-ou have, at some peripheral portion of the body, a permanent source of irritation, such as a wound (particularly if in a state of high inflamma- tion) would afford, you will have, through the exodic nerve proceeding from this point, a constant series of impressions conveyed to the spinal marrow, and consequently a constant series of reflex influences con- veyed through the exodic nerves to the peripheral muscles, producing a constant state of spasm — or, in other words, tetanus. Such I conceive to be the pathology of this disease, in whatever form it may present itself. Writers divide it into traumatic and idio- pathic ; but I am inclined to think, that if we could analyse strictly every case of idiopathic tetanus, so called, we should find its patho- logy to correspond with that of the traumatic variety, both being re- solved by the principles which I have just endeavored to explain. In every case of tetanus, I believe that you will, find an exalted condition of the function of the spinal marrow and a local point of irritation, be that point in the spinal marrow itself, or, as it most usually is, at some peri- pheral portion of the body. These views are borne out by the case I am about to report. It would ordinarily be laid down as a case of idiopathic tetanus ; but that there was in this case a local point of irritation, I think is highly probable from its history, and that that point was the uterus, which had but the week before been the seat of a process well calculated to produce serious inflammatory action, I can scarcely doubt ; and if so, in what respect would this case differ from a case of ordinary trauma- tic tetanus. On Sunday, September 15th, I was called, in consultation with Dr. Wm. A. Patteson, to see Mrs. , of whose case I obtained from Dr. Haxall, the attending physician, the following histoiy : Mrs. is about 27 years of age ; has been married nine years, and has borne four children. Her general health has been very good. On Tuesda}T, 3d September, being about six weeks advanced in pregnancy, she experienced some pain in the loins, which was soon followed by haemorrhage. The occurrence of these symptoms she at- tributed to fright. During the day, Dr. Haxall saw her, but was not permitted to make an examination. Ordered acetate lead and opium, external application of cold — strict rest. Johnson's case of tetanus. 31 Wednesday j 4. Haemorrhage continuing, an examination was in- sisted on, which disclosed the placenta presenting itself at os tineas, which was slightly dilated. Tampon was applied, strict rest enjoined, and all other remedies discontinued. No haemorrhage occurred after the application of the tampon. Thursday, 5. Tampon being removed, a portion of the placenta came away. No additional haemorrhage. Tampon re-applied. Friday, 6. Remainder of the foetal mass came away to-day, unac- companied by any haemorrhage. Tampon was discontinued. At this time her pulse wras good, her appetite good, and she made no complaint. Saturday, 7. Found her sitting up in bed sewing. Enjoined entire rest. Sunday and Monday she remained in bed, but appeared quite well. On Tuesday, 10th, Dr. Haxall left home, and Dr. Patteson saw her ; she was then sitting up and appeared quite well. On that day, after the doctor's visit, she engaged in a romp with one of her friends, and afterwards sat by an open window for some time. On that night (or the next?) she also sat by an open window, watching a fire that was in progress in the immediate neighborhood. On Wednesday, 11th, she experienced some slight stiffness of the jaws, which continued with a slight increase up to Saturday, when her husband consulted Dr. Patteson. On Sunday, Dr. Patteson saw her about 3 o'clock, when he ordered her calomel and Dover's powders, aa grs. x. At 7 o'clock on Sunday evening, I visited her with Dr. P. When I saw her, the case presented the following symptoms : The patient lay on her back with the head drawn slightly backwards and resting on the occiput ; the muscles of the back of the neck were in a state of tension, though not excessive; the jaws were closed .quite firmly, the patient not being able to open them more than ^ inch ; the masseter muscle was firmly contracted, and its fibres could be felt hard and resisting as when the teeth are strongly closed by a volun- tary effort. There was considerable difficulty in swallowing, every attempt to do so being accompanied with pain and an increase in the tension of the muscles. She complained of severe pain just below the sternum, passing through to the right shoulder, doubtless caused by spasmodic action of the diaphragm. Her pulse was soft, com- pressive and more frequent than usual, probably 95. Her skin was relaxed and covered with slight perspiration, and she was suffering somewhat from nausea, caused probably by the Dover's powder wrhich had been administered. She was directed to take Hoffman's anodyne 3j, black drop gtts xx., every three hours, and to inhale sulphuric ether, which Dr. Patte- son had already exhibited, through the night, "pro re nata;" and in the morning to take a tablespoonful of castor oil. September 16th, 9 o'clock, A. M. Pins taken two doses of the ano- dyne and repeatedly inhaled the ether. During the morning has dozed a good deal. Did not take the oil until a few minutes before our visit. Her condition very similar to that of last night ; complains very much of the spasm of the diaphragm. Directed to continue the use of ether, to take a teaspoonful of oil in three hours; and if the bowels 32 Johnson's case of tetanus. were not then opened, to have a stimulating enema. Dr. Patteson visited her at 3 o'clock, and finding that only the lower bowels had been evacuated, directed Croton oil, gtt ij, in mucilage, to be repeated in two hoars if it did not operate. At 6 o'clock, P. M., we visited her together, and found that the bowels had just been fully evacuated, the passage not being very offensive, and presenting a healthy and natural appearance. She was more quiet, complained less of the diaphragmatic pain, and seemed to swallow with more ease. During our visit, a tendency to tetanic spasm coming on, it was speedily controlled by the exhibition of the ether, under the influence of which she became composed and relaxed. With the view of favoring the purgative action of the oil, she was directed simply to continue the use of the ether, and only to resort to the anodyne in case of excessive purgation or great tetanic action. September 17. We were summoned about 7 o'clock this morning to see the patient, a tendency to syncope having occurred upon raising her in bed. We found her with a very pallid countenance, increased tension of the elevator muscles of the lower jaw, and increased tend- ency to spasm of the muscles of the back of the neck ; the pulse more feeble, though not indicating great prostration. She had passed a tolera- bly quiet night, inhaling the ether frequently, and being always relieved by it. She had had two more evacuations of the bowels. She com- plained more of the diaphragmatic pain than last night. She was direct- ed assafcetida 3 ij., opium grs. xvi., water 1 iv., an ounce of which to be thrown into the rectum every two hours ; also a blister to be applied over the spine three inches wide, from the nape of the neck to the dorsal region. Beef tea ordered for nourishment, and occasionally a little toddy. We saw her again at 3 o'clock ; two clysters had been administered, the blister applied and some of the beef tea taken. She had continued to use the ether. There was an abatement in the spasm of the muscles, and she had been much more quiet and com- posed. At 6 o'clock, P. M. — Still farther improvement ; she can sepa- rate the jaws sufficiently to admit the index finger; complains of no pain; pulse more full, and countenance less pallid and more natural. During the day the parts over the affected muscles were constantly anointed with an ointment of aconite. Directed to dress the blister with stramonium leaves, and to continue the above remedies "pro re nata. " September 18. Passed a comfortable night ; rigidity of muscles about the same as last night ; complains of no pain ; pulse a little ex- cited and skin a little warmer than natural. Directed to use ether less freely ; to take beef tea and the assafcetida enema if necessary. At 3 o'clock had not taken the enema. Ordered her a cathartic ene- ma, which was given, and followed by free evacuation of the bowels. At 6 o'clock, P. M., found her very restless ; the spasms increased; constant tendency to throw the head backwards and some slight ten- dency to opisthotonos ; complains again of diaphragmatic pains. Ordered 25 droits of black drop in a teaspoonful of Hoffman's anodyne, immedi- ately to be followed by the anti-spasmodic enema; these to be admi- nistered through the night "p-o re nata; " the ether to be used freely. TRANSACTIONS OF MEDICAL SOCIETY OF VIRGINIA. 33 We left her about half an hour after the administration of the first dose of the anodyne, sleeping quietly. September 19. Passed rather an uncomfortable night, sleeping but little. Took three doses of black drop and Hoffman's anodyne and several enemata. The spasms are persistent to-day ; condition very much as last night. Directed her to take 50 drops of black drop every two hours, to use the enemata, and to drink milk toddy and julep. At 2 o'clock she was more calm, and had passed a more quiet morning. Ordered her croton oil, two drops every two hours, until the bowels were evacuated, and a solution of extract Indian hemp in 1 gr. doses every two hours. At 6 o'clock, found her more feeble, her respiration much more difficult and wheezing. Her voice was al- tered, indicating an evident contraction of the "rima gloltidis." Her pulse was feeble and countenance pallid. From this time she continued to grow worse, the respiration be- coming more and more laborious, until about 10£ o'clock, when she expired, apparently from asphyxia. In reply to questions asked by several members, Dr. J. stated that the ether was administered constantly and sometimes until complete anaesthesia was produced. It was taken with much avidity, and greatly relieved the agony of the patient, but did not relax the spasms. Dr. Snead entirely concurred in the opinion which had been ex- pressed by Dr. J., and believed there was no such thing as idiopathic tetanus ; that there must always be irritation, if not a wound, found in some part of the body, from which the impressions giving rise to teta- nus emanated. • In this case he thought it was unfortunate that the womb was not examined. Dr. Johnson replied, that it was determined in consultation that no good could result from such an examination, and it was therefore not made. He did not, however, defend the opinion. Dr. Gibson believed, notwithstanding the opinion wThich had been expressed by other gentlemen, that there was such a thing as idiopathic tetanus, and proceeded to draw the distinction between the two forms, calling those traumatic which could be traced to a wound as the ex- citing cause, and all others idiopathic. The case under consideration he thought was traumatic, the womb being the seat of the injury. Dr. Cunningham remarked, that it had been his lot to see thirteen cases of this formidable disease, and that he also believed in the ex- istence of pure idiopathic tetanus. In two of his cases there was no wound whatever. The first was a very formidable one, attended with as violent symptoms as any case of traumatic tetanus. It occurred in a child, and was produced, he believed, by worms. The other oc- curred in the person of a laborer in a rolling mill, who slept in a cold place after being heated and fatigued. He suffered violently with te- tanus three or four weeks. In this case he used the most active pur- gation, with calomel, croton and castor oils. The patient recovered. Dr. Johnson said he had been misunderstood. If the absence of a wound was sufficient to establish idiopathic tetanus, then he be- lieved in it, and these were cases ; but, according to the position he had 3 34 TRANSACTIONS OF MEDICAL SOCIETY OF VIRGINIA. taken, mere irritation of any part transmitted to the spinal marrow, and finding it with an exalted excitability, might produce tetanus. In Dr. Cunningham's cases, intestinal worms produced the irritation in the one, and the effect of cold in the other. Dr. Cunning-ham replied to an enquiry, that both of the cases were attended with opisthotonos. He then said, that although the pathologi- cal difference, based upon their exciting cause, was not clearly defined, a practical difference between the two forms seemed important, inso- much as idiopathic (or the chronic tetanus of writers) was less danger- ous than the traumatic or acute. Dr. Brockenbrough remarked, that in 1842 the county of West- moreland was visited by a great many northeasters, and he de- tailed two or three cases of this disease produced by them, which terminated fatally. He regarded them as cases of idiopathic tetanus. Dr. Scott preferred to read what he had to say on this subject, whereupon he proceeded to read a paper, which will be found on file. In it he commented upon the views of several authors — Wood and Watson among them — and thought them rather vague, teaching but little whereon we could build any rational treatment. He preferred to adopt the conclusions of Marshall Hall, as they were based upon experiments which he thought satisfactorily proved this to be a disease of the excito-motory system. The terms centric and eccentric he thought much better to express the different forms of the disease, as they were much more definite than idiopathic and traumatic. He referred to Trousseaus' account of the effects of strychnine, and said that he be- lieved in tetanus the same organs were not only affected, but they were in the same condition as when under the influence of strychnine. He attributed the occurrence of sleep in the disease, to an exhaustion of the superabundant nervous excitability. Patients sleep because spasm has relaxed, not that sleep relaxes spasm. During rest, time is given for accumulating a new supply of excitability, and spasms again follow. As to the treatment, Dr. S. had nothing to say, having seen only two cases : they were treated with assafoetida and opium, and, he supposed, calomel — both patients died. Dr. Gooch said he would respond to the call made by the able re- porter this evening, on members, to detail their experience. He had seen a good many cases in this country and in Europe, but was sorry he had not made better notes of them. He had seen cases which he considered idiopathic, according to the accustomed signification of that term, being attended with no traceable injury, inflammation or irrita- tion. He preferred the terms centric and eccentric, and thought it pro- bable there was no centric tetanus : the so-called cases were epileptoid disease. He referred to Dr. Johnson's case, and said he should have deemed an uterine examination necessary. In regard to the tobacco enemeta, he should not have used them, as Dr. Johnson had said, be- cause the tendency of the case was downward, and the patient very feeble — moreover the bowels were opened well. He considered to- bacco in nine cases in ten an invaluable agent. It is directly a ner- vous sedative, and indirectly so, by proving an efficient laxative, ridding the bowels of their irritating load. It was freely used in British prac- TRANSACTIONS OP MEDICAL SOCIETY OF VIRGINIA. 35 tice. Etherization is a great boon to the poor tetanic. But this was only an adjuvant means. He considered the treatment in the case be- fore us, like it most generally is — not curative, but merely •palliative. We should be searching now for some remedy, and no longer relying upon soothing and palliating the most severe symptoms. In this case he thought it exceedingly probable that quinine, in full doses and often repeated, might have saved the patient. We agree that it is a sedative, besides being a fine tonic. In addition to this theory we have evidence in its favor. The case reported to the society last year, by Dr. T. S. G arnett of Westmoreland, has two bearings on this discussion : Firstly, it was one of terrible character, with no traceable cause, (an idiopathic case,) resisting the whole list of remedies most energetically applied ; and, secondly, it yielded to a treatment with quinine and alcohol, adopted when the case was of forlorn hope. Dr. Scott asked how quinine could be both a sedative and a tonic ; and if it was, he did not see the object in giving it for this double effect. Dr. Gooch said, that if the sedative was the principle of cure, (and he believed it was,) he should think quinine a powerful and use- ful drug; and if the spasms could be broken in upon, he should assur- edly use a tonic , and should rather use this anti-periodic, in hopes that it would prevent the recurrence of them. He would answer the other part of the query, by asking another : How is the cold douche both a sedative and a tonic in mania potu? Dr. Haskins said he believed the correct pathology had been stated ; that tetanus was a disease affecting especially that portion of the nervous system concerned in the performance of the reflex func- tions, and consisted in a morbid increase or exaltation of its excita- bility. This no one had denied. Now, assuming this to be the cor- rect pathology, he did not believe the mode of treatment adopted by ourselves, and recommended by the highest authorities, was the true or philosophical one. The remedies used in the case reported, ether, opium, alcohol in some form, and a few other nervous stimulants, make up our list. What principle, he asked, would indicate the propriety of stimulating a nervous system already in a state of hyper-excite- ment? This plan of treatment may be defended, perhaps, upon a principle alluded to by Dr. Gooch. He has said quinine was a stimulant in small doses, and a sedative in large ones ; and we all agree with him. In this admission, however, I do not conceive that any objection to the use of such articles is removed. This phenome- non is in accordance with a well known law of the animal economy, ■ " that undue action is followed by subsequent depression." They cause an expenditure and exhaustion of the super-excitabilit}^ and temporary sedation is produced. This whole class of medicines are, nevertheless, nervous stimulants, though, secondarily, they may be seda- tives. If these remedies operated principally upon that portion of the nervous system involved in the disease, I confess that my diffi- culty would be in a measure removed. But opium, alcohol, &c. act first upon the brain. Ether illustrates it well. Labor throes, respi- ration, &c. go on uninterruptedly, while the patient is in a state of 36 TRANSACTIONS OF MEDICAL SOCIETY OF VIRGINIA. anaesthesia. There is a complete depression of the sensorium at the same time. It then seems to me that all we gain by the use of such articles is the production of insensibility to the pain of the spasms. If, however, it be a correct principle of treatment when we wish to produce sedation in any organ, to do so by stimulating it until we have exhausted its excitabilit}T, would it not be much more plausible to use in this disease strychnine, which we know to act directly upon the excito-motory system ? Would not large doses of strychnine pro- duce the opposite effect of small ones? — the desirable effect. Dr. H. appealed to Dr. Gibson, as a lecturer upon surgery, and one whose province it had been to investigate especially this disease, for his opinion as to the existence of centric tetanus, discarding the old and indefinite terms, traumatic and idiopathic. Dr. Gibson was not prepared to say that there were cases of more centric tetanus than those arising from effusion, pressure on spinal marrow, &c. He differed with Dr. H, and did see great good arising from the use of opium. Patients die of exhaustion, or of asphyxia ; and, as opium gave rest, he thought it very valuable. He highly approved the treatment of the case, notwithstanding the stric- tures of Dr. H, Dr. Johnson said he believed Dr. Haskins' theory and explana- tion of the different effects by different sized doses to be correct. But why not suppose that these remedies act on the spinal marrow di- rectly, as well as on the brain? Is it probable that we only reach this system with them, going round by way of the brain ? We re- lieve colic by venesection and opium. Is it not by direct action on the spine, which furnishes the nervous influence giving rise to the con- tractions ? Dr. Cunningham said we do not act upon the principles of mo- dern pathology : as a London doctor remarked, " It would ruin the practice of physic." In reply to Dr. Haskins, he would ask, why give stimulants through the brain in hysteria or delirium tremens, where we know the nervous system to be in a state of hyper-exalta- tion. We act with the means which we possess, because we know their effects, not because we know how they act. Dr. Haskins replied, that if his strictures upon the treatment of tetanus had been thought to apply to the case under consideration, he had been misunderstood. So far from disapproving the treatment practised by Dr. Johnson, it was what he should have felt himself bound to have done under similar circumstances. But we were here now in the medical society, and should discuss philosophically the principles of treatment indicated by pathology, regardless of the ab- surdities into which we may be led. Dr. Cunningham has referred to the success of nervous stimulants in the treatment of hysteria and mania potu as an argument why they should be used in tetanus. Now, as regards the former of these diseases, though involving principally the same nervous system, we know its form to be entirely different from tetanus, and rarely ever proving fatal — indeed ceasing of itself after a short time, whether medicines have been administered or not. Is it then fair to conclude, that in all cases where medicines have been TRANSACTIONS OF MEDICAL SOCIETY OF VIRGINIA. 37 administered, that they have arrested the paroxysm ? As to mania potu it does not generally depend upon excitement of the nervous system, but on the contrary, is due to the absence of an accustomed stimulus. We can therefore readily see why it should be relieved by stimulation. But the Doctor apprehends that our modern pathology " will ruin the practice of physic." Now he himself has stated that he never saw a case of traumatic tetanus recover under the present practice ; and this is but the concurrent testimony of all the members of the society, as well as all authors who have written upon the dis- ease. It has also been shewn this evening, from statistical tables, prepared by Curling, that of 128 cases, (including every variety of the disease,) only 56 have recovered. I for one, sir, do not feel that we shall sustain any great loss, even though our modern pathology does ruin such practice as this. Dr. Maupin made some remarks upon the general principles of the disease and of sympathy, and said we must fix our disease and its laws by reasoning, and then by experience build a system of treat- ment. Dr. Snead said he wished to be understood as one of those who believe idiopathic tetanus had not been established. Dr. Bolton had seen two cases recently. One supervened on an abscess and erysipelas of arm, and was fatal. He used chloroform in it, and with marked advantage. Dr. Parker remarked that one of the cases referred to by Dr. Bolton was his — traumatic and fatal. He should always use chlo- roform, having seen its great benefit. He had seen an infant aged 13 days, die with congenital tetanus. Dr. Terrill, of Hanover, had used tobacco enemata until com- pelled to desist, together with the usual recorded treatment, in a case of traumatic tetanus, but his patient died. The subject was then informally laid over. Dr. Bolton exhibited a flannel bag of unbroken flies, which he said was given him by a patient from the country, and had been used for 17 years to blister. She said, by moistening one side with warm vinegar and applying to the surface, it would draw in an hour. An additional advantage which this acetate of cantharidin possessed, was, that it was not so apt to produce strangury. December Meeting. After the election of several members and the transaction of some business, Dr. Merritt read an elaborate essay on "congestive fever." As the author of this paper has had great experience in this, one of the most serious diseases of the South, and as we think his views of its pathology and the correct treatment are good, we will publish the main points in our next Number. 38 COLLODION IN ERYSIPELAS. Collodion — Its Use after Leeching and in Erysipelas. Like most other American inventions, whether of great or of little importance, this article has been claimed by our trans-atlantic friends. A paragraph passed around the American papers stating that this liquid adhesive plaisterhad been invented by a French chemist — pro- bably a Mons. Alexandre. This is not so ; and, though of no great mo- ment, yet " to render unto Caesar that which is Caesar's," is but just and proper, and I take pleasure in stating that it was first made in Paris by a young American from Boston — I believe, a Mr. Maynard. Charriere, the great instrument maker in Paris, applied it, the day after it was first made, to my hand to cover the wound made by Mr. Alexandre's artificial leech which we were trying — Mons. Charriere applied it, saying that it was a neat preparation made and given to him for trial by our countryman, Mr. Maynard. It is an exceedingly useful substance, and has been applied to all sorts of uses in the arts and sciences. A short time since I had occasion to apply a dozen leeches to an infant of only a few months' age. I was called an hour or two after the operation to stop the bleeding, (which had been twice arrested by cold cloths and pressures, but only for a time.) Other means failing, I poured thick collodion over the bites, previously pressing the surface with a dry towel, and in a few minutes I left my little patient perfectly secure from any recurrence of haemorrhage. We know that children have bled to death from leech bites, and they are sources of no ordi- nary trouble frequently. This preparation is a convenient, comfortable and certain application, and should be always at hand. It is better to apply a thick collodion, so that it may be dried and adherent before any blood can accumulate under it. It seems to be a temporary styptic, and the bleeding is arrested long enough for it to dry, when it is prevented. It usually peels off in from two to five days, and is a source of no inconvenience whatever. It is reported in the " Lancet" to have been used, with great suc- cess, by Mr. Luke, of the London hospital, in the treatment of ery- sipelas. He says, "it would appear that collodion fulfils two import- ant indications ; it protects the inflamed surface from the contact of the air, and it contributes, by the pressure it effects, in driving the blood from the distended capillaries." G — . We believe that the treatment recommended below for scarlet fever has not had as fair a trial as the high standing of its author would de- mand for it. Though Dr. Lindsly's letter is not very recent, we deem the subject one of much practical interest, and give it in full.— Ed. To the Editor of the Boston Medical Journal. Washington, April 11, 1850. Sir : As everything relating to the treatment of scarlet fever, a disease almost as fatal and destructive as cholera itself, is of great in- INUNCTION IN SCARLET FEVER. 39 terest to the profession and the public, I desire to call the attention of your readers to the mode of treatment recommended by Dr. Schnee- mann, physician to the king of Hanover, as contained in a recent num- ber of the London Lancet. The plan proposed by Dr. S. has not re- ceived the attention from the medical profession in this country or in England, so far as my knowledge extends, that its importance de- mands. My experience with it is now considerable, and I think I can safely recommend it as a very valuable addition to our means of con- ducting this dreaded disease to a satisfactory termination. It is phi- losophical and rational in theory — simple and efficient in practice. Its modus operandi will be seen at a glance, and will commend itself to every discriminating physician ; for every one, I think, will admit that the chief weight of this disease falls upon the skin ; and of course whatever tends to restore the deranged functions of this im- portant part of the body will contribute most materially to alleviate all the symptoms. The employment of this remedy of course will not prevent the use of such other means as experience sanctions, and each particular case calls for, as laxatives, febrifuges, application to the throat, internal and external, &c. I hope a fair trial will be given to this mode of treatment by the profession, and the results made known through the journals, that its true value may be definitely ascertained. I subjoin the most impor- tant directions given by Dr. Schneemann, in a somewhat abbreviated form. HARVEY LINDSLY, M. D. Treatment of Scarlet Fever ly Inunction.- — From the first day of the illness, and as soon as we are certain of its nature, the patient must be rubbed morning and evening over ihe whole body with a piece of bacon, in such a manner that, with the exception of the head, a co- vering of fat is everywhere applied. In order to make this rubbing in somewhat easier, it is best to take a piece of bacon the size of the hand, choosing a part still armed with the rind, that we may have a firm grasp. On the soft side of this piece slits are to be made, in or- der to allow the oozing out of the fat. The rubbing must be tho- roughly performed, and not too quickly, in order that the skin may be regularly saturated with the fat. The beneficial results of this appli- cation are soon obvious. With a rapidity bordering on magic, all, even the most painful symptoms of the disease are allayed ; quiet, sleep, good humor, appetite return, and there remains only the im- patience to quit the sick room. The advantages of the treatment indicated may be summed up as follows : 1. The improbability, we might almost say the impossibility, of the patient getting cold while the skin is thus covered with fat, a point in no disease more important than here. 2. The dry brittleness of the skin and the tormenting itching are by it not only materially alleviated, but generally entirely removed. 40 SPECULUM IN UTERINE DISEASES. Every practitioner knows how often the itching and burning of the skin in scarlet fever are unendurable to children, keeping them con- stantly in distressing movements, and robbing them of sleep. Hence children are generally well satisfied with this process, and often ask for its repetition long before the time is come. 3. The influence on the physiological functions of the skin is still more important. Daring the coming on of scarlet fever the skin be- comes diseased, in consequence of which it loses its vital power. During this illness, and until a new covering is again prepared for the surface, the functions of the skin are very imperfectly performed, or during the desquamation probably not at all. In order to explain the extent and importance of the imperceptible functions of the skin in a merely mechanical view of the matter, the reader is referred to the accurate experiments of Seguin, which fix the quantity of matter thrown off from the outer skin at eleven grains per minute in a grown person, therefore more than two pounds per day. What efforts must it cost the organism to lead so large a quantity into other paths, in order to throw it off, when the skin is incapable of doing so ! 4. With this disappearance of the desquamation disappear all those bad symptoms which attend on it. In order to give a striking proof of the importance and bad influence which the interrupted functions of the skin produce on the healthy activity of relative, even if dis- tant, organs, we may cite the fact that death is always the result where more than one-half of the skin has been destroyed by fire or boiling liquid. A similar destruction of the skin ensues in scarlet fever, with this difference — it takes place gradually, and thereby the organism is better enabled, by employing all the activity of the body, to find aid against the mischief which must result from the cessation of the func- tions of the skin. The Speculum in Uterine Diseases. At one of the meetings of the Royal Medical and Chirurgical Soci- ety of London, the distinguished obstetrician, Dr. Robert Lee, read a paper on the use of the speculum in the treatment of uterine diseases. Quite a bitter warfare has since been going on between the friends and opponents of the instrument, among whom are many of the most eminent English physicians. It seems very strange that such diversi- ty of opinion and observation should exist as to the real condition of the membrane about the os and cervix uteri. Some insist that there is never any ulceration, abrasion, &c, unless of specific character, and Dr. Ash well is one of these. That author has said " that the use of the speculum has almost become a professional dishonor, and that the necessity of employing it as frequently as it is now employed by respectable practitioners, would compel him to retire from the practice of diseases of women." In commenting upon the views of SPECULUM IN UTERINE DISEASES. 41 Dr. Ashwell, and his " unguarded expression," Dr. Tilt, a gentleman who has lately put out a work on " the diseases of menstruation" which will elevate him to the highest rank as an author, very tersely remarks: "I can easily understand that a noble nature should aspire after a better world, where there may be no distinction of sexes, and where no obstetric physician will be required to meddle with delicate organs. But as long as there are bond fide women in this sublunary sphere, those organs which constitute them women must be assisted in their functions and ministered to in their diseases, and unless the medical attendant is himself indelicate minded, there is, as Dr. Locock tersely remarked, no more indelicacy in doing so than in curing a sore throat by cauterizing the tonsils." The reader is referred to the Lancet for the very interesting debate and communications on the subject, but as we think the following let- ter as applicable here as in England, if not much more so, we give it. " To the Editor of The Lancet. " Sir — If you will allow me space, I would offer a few remarks on the use of the so much abused speculum uteri. I have for some time adopted it in my practice, and have found it so valuable an aid to diagnosis and treatment, that I consider its use in uterine disease as indispensable as is the stethoscope in affections of the chest. In proof of this assertion, I would cite the following case, which re- markably illustrates not only its utility, but its necessity. I was consulted, about four months since, by a married lady, who presented symptoms of uterine disease, and on stating this to be my decided opinion, I was requested by her mother at once to ascertain the fact. On examining with the finger per vaginam, the labia uteri presented that velvety feel described by Dr. H. Bennet as indicating the exist- ence of ulceration, and also considerable induration ; my diagnosis was afterwards confirmed by the speculum. I lost sight of this pa- tient until very recently, when she again requested my attendance. I found her with all her symptoms much aggravated. She told me that she had been under the care of one of the obstetric physicians who are now taking so prominent a position in the present anti- speculum crusade, and who had been occasionally attending her during the last seventeen years. This gentleman had always de- clared that she was laboring under stricture of the rectum, for which he had been diligently drugging her during that long period. In this opinion he was strengthened by another eminent obstetric physician of the same school, who occasionally saw the patient. On becoming worse she again sought my advice, but I declined any interference unless I was permitted to make a thorough investigation of her case. To this she willingly consented. I first passed my finger easily into the rectum, through which it was declared " a crow-quill could not enter." I felt a hard, projecting tumor, completely filling the hollow of the sacrum. This I discovered, on examination per vaginam, to 42 EXCHANGES. be the retroverted fundus uteri, much enlarged, and excessively tender to the touch. The labia uteri presented unmistakable granular ulcerations, with induration extending up the walls of the cervix. Now, I would ask, am I to believe the evidence of my senses, or am I to take the opinion of men who would not for the world use that dangerous instrument called Simpson's uterine sound, and w7ho are of too pure a school of medical ethics to make a vaginal examination ? I would ask the profession, in sober earnestness, are we to accept the dicta of such men, as to the use of instruments which many of us have proved to be of incalculable value, and which have been intro- duced to us by men certainly of as high professional standing as any who oppose their employment. Of what value are the opinions of those who either declare that they have never derived any information whatever from the use of the speculum, or who altogether ignore the use of instruments in uterine diagnosis ? " Whilst I am upon the subject, in conclusion, I would hint to Dr. Marshall Hall, that should his opinions become known to the wives and daughters of England, they would repudiate his championship of their morals, and would throw back upon him with indignant scorn the sentiments he has dared to attribute to them. " Requesting you will favor me by giving insertion to this letter in your forthcoming journal, "I remain, sir, your obedient servant, "W. Moon." OUR EXCHANGES. Our thanks are due to the editors of the following works, who have been good enough to commence exchanging in prospectu. We wel- come them to our table, and hope that our acquaintance will be mu- tually agreeable. The New York Register of Medicine and Pharmacy, a neat semi- monthly of 16 pages, edited by Dr. C. D. Griswold. We have re- ceived the six numbers issued, and are much pleased with it. The December (15th) Number, after noticing our prospectus, goes on to say : " It is often remarked that we have already too many medical jour- nals, more than can be supported, &c.,and we have no doubt but that the same kind of objections have been urged against each new publica- tion, since the first one was established in this country. Franklin was advised not to set up a second newspaper in Philadelphia, on the ground that it could never be sustainecl, as Philadelphia had already attained its full growth ; and so it is, that there are always prudent ones, who advise against any undertaking for which they may be called upon to subscribe. We may have too many journals, but we have not enough good ones, nor are xhey sufficiently well patronized. Let every EXCHANGES. 43 man double his subscription list for one year, and after that time it will cost him but little if any more than he now pays — such is the influ- ence of patronage upon the press. With a proper spirit of indepen- dence, the medical journals of this country might do much to relieve the profession from its worst evils ; but as it now is, the doctors are handled more like sick babies, and their defects covered up writh the scrupulous care that a foolish mother would screen the errors of her spoiled boy. The truth is, our journals, or many of them, are con- servative to a degree which impairs not only their own interest, but lessens the good they might do the profession. We do not like to see the many suffer from the errors or vices of the few, and it is not right that it should be so. A journal that has no character or principle or opinions independent of the communications upon its pages, is not worth having. As with the stethoscope we ascertain the condition of internal structions, whether they are healthy or unhealthy, so through our Virginia cotemporary, may we have revealed to us the true condition of the heart of the profession." The Southern Medical and Surgical Journal, a good monthly, 64 pages, edited by Dr. J. P. Garvin, Augusta, Georgia. We perceive by the December Number that this work will in future be conducted by Professor L. A. Dugas, of the medical college of Georgia. This gentleman is the successor in the chair of surgery to Dr. Paul F. Eve, who was last year appointed to Dr. Gross' vacant chair in the university of Louisville. We see by an advertisement that " Dr. Eve will resume the practice of his profession in the city of Augusta by 10th March 1851. We suppose, then, that Dr. E. will resign his new professorship and go back to the field of his old labors. He is the chairman of the committee on surgerv of the American medical association, and asks that communications may be forwarded to him to Louisville or Augusta either. Though " the editor, publisher and printers were all suffering from break-bone fever" they got out a very good number. It opens with the conclusion of a very interesting paper " On the present state of Medicine," by Dr. C. Todd Quintard, of Roswell, Georgia. Its peri- scope is well made up. The Boston Medical and Surgical Journal, a weekly of sixteen pages, and a number of advertisements. Its editor, Dr. J. V. C. Smith, is writing letters, interesting enough to the general reader, from the East. His last is from Alexandria, and is principally devoted to the harem, the city, and other things not medical. We see by this paper that there are negro medical students in the Harvard university ! and a white woman. The students remonstrated, but to no purpose. This paper publishes the marriages of the Massachusetts doctors, and we 44 VIRGINIA MEDICAL SCHOOLS. are pleased to see that our old friend Prof. Jeffries Wyman, late of the Richmond medical college, has " taken unto himself a wife." The New York Medical Gazette and Journal of Health, weekly, edited by Dr. D. Meredith Reese : a medical newspaper, worth to New Yorkers its subscription. It tries to conciliate the Southern medical students to the Northern colleges. The Northern Lancet and Gazette of Legal Medicine, edited by Dr. F. J. D'Avignon and Dr. Horace Nelson, of Plattsburg, New York : a double column octavo, very indistinctly printed, and not much of a " Northern Light?'' in medico-legal science. We adopt, however, his notice of The American Journal of Medical Science. Dr. Isaac Hays, Phila- delphia. " This excellent journal needs no recommendation of ours in inducing the profession to extend their patronage to a publication which may be considered as truly American." The Philadelphia Journal of Pharmacy, another national work of great value, most particularly to all apothecaries and country prac- titioners, who are necessarily both prescriber and compounder. To this work we shall look to keep us posted in the new preparations. The London Lancet, which is so expeditiously re-printed in an un- abridged form by Messrs. Stringer & Townsend of New York, is fur- nished us by Messrs. Morris Sf Brother. This work we would not be without, and its circulation is so general we need not say a word in its praise. dSP" Other works receiving this Number will please exchange. Authors and publishers sending works for review, will please do so through the Richmond booksellers, or, post paid, by mail. VIRGINIA MEDICAL SCHOOLS. It is a source of pride and congratulation among Virginians to see the present flourishing condition of our colleges, and to know that they are rapidly assuming that position which their merit demands, and which it is the duty of every Virginian to aid them in attaining. The stigma upon the state, that it cannot educate its own sons, is being rapidly wiped away ; and the time is close at hand when we will no longer be going to the North to seek fountains of wisdom and learn- ing. The present session of our medical schools proves that a proper feeling of state pride is being awakened, and we feel quite confident MEDICAL SOCIETIES- 45 that in a few years our state will occupy the position in medicine with the South that Philadelphia once did with the whole Union. The climate of any city further South than Richmond is too warm for an- atomical pursuits, and evidence is abundant that Southern medical students are not going further North. So we are warranted in the be- lief that this state is soon to become the seat of the great medical school of the South. We know that the older members of the pro- fession were all educated in Philadelphia, and that they have that love and veneration for their alma mater which is so natural. But we believe that they are also duly impressed with the importance of throwing off that vassalage which bound us to the North, and which circumstances no longer render necessary. The progress of medicine has been so rapid, and the means of communicating it has become so much facilitated, that there is no longer that centralization of Ameri- can medicine necessary as was the case when our country was young and its population sparse and scattered. The Medical college of Richmond has a much larger class than ever before, and the proportion of second course students is very great. The faculty are lengthening their course, and steadily raising their standard of graduation. The medical class of the University of Virginia is unprecedentedly in- creased, and far greater in proportion than any of the academic de- partments. This speaks well for professional education in Virginia, as the university is universally granted to be the most thorough drilling or preparatory course in our country. The Winchester medical college has a very respectable class, and we learn the professors are advancing its interests with a zeal and in a manner worthy of the praise of the profession. The medical department of Randolph Macon college is also on the in- crease, and we believe preparations are being made there to extend the course. From want of accurate information, we defer stating the numbers,, &c. of our schools, but we will do so in a future number. MEDICAL SOCIETIES. We give in the present Number an abstract from the very interest- ing debate in the Medical Society of Virginia at its November meet- ing. This body holds regular meetings, on the third Tuesday of every month, in the hall of the Richmond library association, corner 46 PURIFICATION OF CHLOROFORM. of Main and 11th streets. Its annual meeting is in May. Its officers for the present year are : President, Dr. Ro. W. Haxall ; vice-presi- dents, F. Marx and James Beale ; secretary, P. CI. Gooch ; corres- ponding secretary, Carter P. Johnson ; treasurer, James Bolton ; li- brarian, W. J. Clark. The society is in a very flourishing condition, and has a large number of members throughout the state. In a future Number we will give a full account of its organization and history. We learn that societies exist in Petersburg, Norfolk, Fredericksburg, at the University of Virginia, Wheeling, Loudoun, and in Greenbrier county. There are others, doubtless, in the state, and some of them are prospering. We would be glad if the secretaries of these bodies would furnish us with their proceedings for publication. It is said, "that the medical press is the nurse of medical talent;" so, we con- ceive, are medical societies. If the profession would be more careful not to use articles which are not pure, less complaint would be heard of remedies of all sorts which produce good or bad effects according to their preparation. If chloroform were always as good as it should be, we believe many of the bad consequences attributed to it would never have been heard of. For the benefit of our readers who do not take the American Jour- nal of Pharmacy, we publish the following article of Dr. Gregory, to- gether with the editor's remarks : Notes on the Purification and Properties of Chloroform, read before the Iloyal Society of Edinburgh, by William Gregory, M. I)., Professor of Chemistry in the University of Edinburgh. 1. Chloroform has been prepared both from alcohol and wood- spirit. The latter has been used for the sake of cheapness ; but as it is a mixture of several liquids, all of which do not yield chloroform, it gives an impure product, in a proportion which varies much, but is always below that obtained from alcohol. There is therefore not only no advantage, but the contrary, in using wood-spirit, which is not, after all, much cheaper than alcohol. 2. But the chloroform from these two liquids, when fully purified, is quite identical in all its properties. Its smell, density, boiling-point, and action in the system, are in both cases exactly the same. That from alcohol is no doubt more easily purified than the other, but it also contains certain volatile oily impurities, which must be removed be- fore it can be safely used. The peculiar oils which adhere to both kinds of chloroform are not identical, or at least, not all identical, but they are of analogous constitution and properties. PURIFICATION OP CHLOROFORM. 47 3. Soubeiran and Mialhe have examined these oils. They contain chlorine, have a disagreeable smell, and when inspired or smelt cause distressing headache and sickness. In the case of wood-spirit, some of its own impurities distil over unchanged, and are also found in the chloroform. 4. It is well known that many persons, after the use of chloroform, have suffered from headache, nausea, and even vomiting, as I have more than once seen. Headache and nausea I have myself often ex- perienced, when I have tried different specimens of chloroform, with- out taking so much as to produce the full effect. 5. Perfectly pure chloroform does not, so far as I have seen or ex- perienced, produce these disagreeable effects. It is therefore highly probable that when they occur, as they do with some individuals, from the use of chloroform of more than the average goodness of quality, they depend on the presence of a trace of these poisonous oils. 6. All good manufacturers of chloroform purify it by the action of oil of vitriol, which destroys the oils, while at the same time a part of the acid is reduced to sulphurous acid. The chloroform, to remove this, is then distilled with lime or carbonate of baryta, and is tolerably pure if the process be well conducted. 7. But it is not quite pure, and contains a trace, more or less dis- tinct, of the oils. I have found this to be the case with all the best chloroform made here up to 1849 ; and I have several times seen headache and sickness from the use of such chloroform, which was the best anywhere made. I must add, however, that the quantity of oils in the chloroform of the best Edinburgh manufacturers, although variable within certain limits, was always so small, that that product was fit for use, and only caused headache, &c. in a few peculiarly sensitive persons. 8. It was desirable to have a test for these impurities, as well as an easy and effectual mode of removing the last traces of them, especially as many sorts of chloroform not made here were far inferior in quality to that prepared in Edinburgh. One very delicate test is, that of oil of vitriol, which should be quite colorless, pure, and of the full den- sity of 1.840 at least, as it may be obtained by Mr. Kemp's process, lately read to the Royal society ; when agitated with the chloroform, it becomes yellow or brown, from its action on the oils, which it chars and destroys. Any change of color is easily seen by contrast with the colorless chloroform which floats above. Pure chloroform gives no color to the acid. It is essential that the oil of vitriol be colorless and also of full density ; for if colored, it is not easy to see a slight change on its color ; and if below the proper density, that is too weak, it is not much colored by a chloroform which will render dark brown the acid of proper strength. 9. Another test, still more delicate, I find to be the smell of the oils. When chloroform is poured on the hand or on a handkerchief, it ra- pidly evaporates ; but the oils, being less volatile, are left behind ; and their smell, previously covered by that of the chloroform, is easily re- cognised. Until very lately no chloroform was sold, or indeed known, which would, stand this test, or even the former. 48 * PURIFICATION OP CHLOROFORM. 10. Up to 1849, the best commercial chloroform had a specific gra- vity of 1.4S0, which was- considered a guaranty of its purity ; but it had been obtained by chemists of specific gravity 1.494, and even 1.497. I have found that chloroform of 1.480, when once more acted on by oil of vitriol, which destroys the oils and becomes brown, may be obtained after removing the sulphurous acid, of specific gravity 1.500 at 60°. This I take to be the specific gravity of pure chloroform. Our best makers have lately, much to their credit, pushed the purification so far as to furnish chloroform even of this highest density, and also in other respects such as it ought to be. 11. There are still, however, many makers in other places whose chloroform is not so pure ; and I shall now describe the method which, with Mr. Kemp, I have employed for purifying, perfectly and easily, any commercial chloroform, except one remarkable specimen — a process which will enable any medical man to purify it for himself with the greatest facility. 12. The chloroform, having been tested as above, and found more or less impure, is to be agitated with the oil of vitriol, (half its volume will be sufficient,) and allowed to remain in contact with the acid, of course in a clean, dry and stoppered bottle, and with occasional agita- tion till the acid no longer becomes darker in color. As long as the action is incomplete there will be seen, after rest, at the line of con- tact, a darker ring. When this no longer appears the chloroform may be drawn off, and for greater security once more acted upon by a quarter of its volume of the acid, which should now remain color- less. It is now to be once more drawn off, and, in a dry stoppered bottle, mixed with a little powdered peroxide of manganese, with which it is gently agitated, and left in contact until the odor of sul- phurous acid is entirely destroyed and the chloroform has acquired a mild, agreeable, fruity smell. It has then only to be poured off into a proper phial. It will now leave no disagreeable smell when evapo- rated on the hand. [If the commercial chloroform, after having been frequently well shaken and left for some time in contact with the acid, has given to it only a moderate tinge of color, it is probable that it may be completely purified by the first process. To ascertain this, test a fresh portion in a tube with fresh acid, shaking well, and allowing it to stand for some time. If it do not color the acid at all, then the whole chloroform has only to be finally purified by the oxide of man- ganese. If the acid become colored in the test tube it will be as well to act on the whole chloroform a second time with fresh acid till it stands the test. Mr. Kemp has observed, in repeating this process for me, the very curious fact, that as soon as the action is complete and the oily impurities are destroyed, but not sooner, the chloroform tested with the acid in a tube exhibits a strongly convex surface downwards, where it rests on the pure acid, or what is the same thing, the acid becomes concave at its upper surface. The smallest trace of impurity, not sufficient to affect the density of the chloroform, we have found to render the line of junction horizontal. It is probable that this may become a valuable test of the perfect purity of chloro- form ; but we shall not say more on this subject until we have PURIFICATION OF CHLOROFORM. 49 thoroughly examined it.] This process requires no apparatus be- yond a few stoppered bottles, and a pipette, if we wish to draw cfFthe whole chloroform without loss, although nearly the whole may be simply poured off. The use of the oxide of manganese is due to Mr. Kemp, and on the large scale the chloroform may be filtered through a cylinder full of it. In this final purification of commercial chloro- form no distillation is necessary. Indeed, no rectification is required at all if it be well washed with water before using the acid. 13. It may be considered as certain that the use of chloroform thus purified will very rarely, if ever, cause the disagreeable effects above noticed.* As to more serious bad results from the use of chloroform, so often spoken of elsewhere, it is enough to state that a large proportion of the cases must be attributed to the use of a liquid so impure as hardly to deserve the name of chloroform at all. Postscript. — Since writing the above, my attention has been called to a paper by Dr. Wilson, on the specific gravity of chloroform, which he was not able to obtain higher than 1.49S. I have therefore to add, that every specimen, whether of specific gravity 1.480, 1.490, or 1.497, which I purified as above, acquired the same density of 1.500, as ascertained by the use of a very delicate and accurate bead, (made by Lovi,) which sank at 60.°5 and rose at 59.°5 ; and also by three successive weighings with a very delicate balance. It will also be seen, that three commercial specimens had this density; I could de- tect no foreign matter in my chloroform ; and besides, every foreign matter that is likely to occur lowers the density. 1 have no doubt that Dr. Wilson's specimens would have colored the acid and left a smell on the hand. I may add, for the maker, that after distilling the materials which yield chloroform, no distillation or rectification is needed. He has only to wash the heavy fluid with water till its volume no longer di- minishes, and then to use the oil of vitriol as above, finishing with the oxide of manganese. Distillation with the acid is of no use, because no proper contact can take place, the chloroform distilling from the surface as it would from mercury. In testing by oil of vitriol, it is * Dr. Simpson informs me, that the purest chloroform he has used not unfrequently causes vomiting. On further enquiries, I find that this occurs when it is administered after a full meal. This can easily be avoided, and must not be confounded with the headache, nausea and vomiting alluded to in sections 4 and 5; which symptoms are persistent, and occurred in my experiments alwnys with an empty stomach, the experiments being made an hour or two before dinner. Mr. Carmichael, assistant to Dr. Simpson, has mentioned to me some facts which conlirm the view I have taken. At one period, for more than a week, Dr. Simpson and Mr. Carmichael were kept in a state of continual anxiety by the occurrence, in all the puerperal cases in which chloroform was used, of very unpleasant symptoms, particularly of frequent pulse and other febrile symptoms, lasting for some days. At last, after much annoyance from this cause, it occurred to Dr. Simpson that he was using one particular specimen of chloroform above the average in quality. As soon as this idea occurred he threw away all that remained, and returned to that which he had generally used. The unpleasant symptoms no longer appeared. [I regret much that I had not an opportunity of examining that specimen, but I may add that the maker, not an Edinburgh one, now produces chloroform of much better quality, though not yet absolutely pure.] But the striking fact is this, that Dr. Simpson and Mr. Carmichael state, that during the period above alluded to, when that one kind of chloroform alone was used by them, their handkerchiefs became quite offensive from the smell left on them, which even adhered to them after washing. There can, I think, be no doubt that here the oily impu- rities alluded to in sections 4 and 5 were present in notable quantity. 4 50 PURIFICATION OF CHLOROFORM. best to use some ounces of chloroform, and to shake it in a phial, be- cause in a test-tube, the color produced, if not strong, may be over- looked. While I acquit the makers of chloroform, who have sold an impure drug, of all desire or intention to adulterate it, I feel it my duty to point out that the system which permits any one to set up as a manu- facturer of this or any other potent remedy, without let or hindrance, without any test of his qualifications, without, in short, enforcing a knowledge of chemistry and pharmacy as an essential condition, is a radically bad one ; and that our law, in relation to druggists and apo- thecaries, requires reformation. In fact, the evils naturally resulting from it are only neutralized, and that but in part, by the good feeling and principle of the leading manufacturers. To illustrate this, I may remark, that some of the makers of chlo- roform must have been very ignorant, even of what was known and published concerning its properties; for, among the specimens I ex- amined, are several of specific gravity below 1.4S0, which was long ago given as the standard, even so low as 1.347. That this neglect proceeded more from ignorance than from inten- tion, is, I think, plain, from the fact, that a specimen labelled "Pure Chloroform" actually contained only a trace, about one-thirtieth, of that substance. I did not ascertain its specific gravit}", which must have been far lower than 1.200 or 1.100 — nay, possibly, under 1.000, because its impurity was so obvious in every other respect, and the quantity I had was too small ; but, on examining it further, I am convinced that its origin was this : — The maker, after distilli^s: the materials, obtained, of course, two liquids, a lighter and a heavier. He evidently did not know that the latter was the chloroform, and therefore threw it away, and preserved the lighter — a mixture of pyroxilic spirit — of its natural impurities, of the deleterious chlorina- ted oils, and a trace of chlorofoim. At least, such are its characters ; and it exactly resembles what would be obtained in the way sup- posed. But what a fearful degree of ignorance (without any evil intention) is here exhibited. And yet this maker was free to produce and sell pure chloroform, which was actually almost pure from chloro- form, and loaded with deleterious agents. [A few weeks since, having occasion for some chloroform, we ob- tained a pound from a manufacturing establishment in this city. On opening the bottle, the odor of the chloroform was contaminated with that of chlorine, and the stopper had on it a greenish yellow discolor- ation. On returning it to the chemist, with the information of its impurity, we received the following note : "Dear Sir — We have your favor of this morning, in regard to chlorine found in chlorofoim, and for the same are much obliged, as it gives us some ground other than our own opinion for declining to make the article by the late improved process with sulphuric acid. We soon discovered that this change was likely to go on, but some of our customers wanting an article of this kind, (i. c. made bv this process) particularly, we were induced to adopt the improve- ment." NITRIC ACID IN ASTHMA. 51 This chloroform bleached moist litmus paper rapidly, first redden- ing it. The acidity is due to hydrochloric acid, generated from the chlorine and moisture adhering to the chloroform operated on by light. Mr. Abraham, in a paper on this subject, has arrived at similar conclusions. — Editor.] Cases of Asthma successfully treated by Nitric Acid. BY T. S. HOPKINS, M. D., OF BETHEL, GLYNN COUNTY, GEORGIA. The following five cases of asthma, cured by the use of nitric acid, have occurred in my practice since the summer of 1847. It is not my desire to attempt any explanation as to the modus operandi of this remedy in the above disease. Its beneficial effects were accidentally discovered, and, after a fair trial in five consecutive cases, with the most entire success, I am induced to bring it to the notice of the pro- fession, trusting that in other hands than my own it may prove a po- tent agent for the relief of a disease which so often resists the best-di- rected treatment. Several of these cases were from twenty-five to thirtv-five miles distant from my office. Most of them were not seen by me from the time of my first visit and prescription until a cure had been effected. I describe them as I found them at the time of my visit, and from the history given by parents and masters, which I think can be depended upon. Case I. — Emma, negro girl, aged five j^ears, belonging to Mr. T. G., had been asthmatic almost from birth. Nightly paroxysms of dyspnoea, cough, &c, were represented as most distressing. During the day, she would be up and about the yard with the other children. At the time that I saw her, her respiration was somewhat embarrassed, with slight elevation of the shoulders during inspiration, and a very distinct mucous rale. Her appetite was impaired, and her countenance cheerless. I ordered nitric acid, three drops, to be increased to five, three times daily, in a wineglassful of sugared water. A month elapsed before I again saw this patient, at which time every symptom of dis- ease had disappeared. I prescribed for her in December 1847, and up to date no symptom of asthma has returned. Case II. — I was called in November 1848, to see W. S., aged about six years, son of a planter of Glynn county. I was informed that this boy had been a subject of asthma for four or five years ; that no expense had been spared in seeking for relief in his case ; and that all the efforts of the best physicians in the neighborhood in which he had resided, had been in vain. When I saw him, he had cough, slight dyspnoea, with mucous rale distinctly audible at the distance of se- veral feet. By walking up and down the steps of the house, once or twice, the difficulty of breathing and cough Would be much increased. He was very lively and cheerful, with a good appetite, and had had no fever for months. His father informed me that, upon the least ex- posure during the day, he would be attacked at night with the most 52 MANGE. fearful symptoms. Wheezing, panting, incessant cough, distressing dyspnoea, with impending suffocation, were the inevitable conse- quences (at night) of exposure during the day. I ordered nitric acid, five drops, three times daily, in a wineglass of sugared water, with a strict avoidance of exposure. In a fortnight, he had been so much relieved that his parents imagined him cured, and discontinued the acid. In a few days he re- lapsed, and I was again sent for. I ordered the acid to be continued, as before, and in one month from the time of my first visit he was cured. Up to date there has been no return of disease. This boy's father died of phthisis pulmonalis. Several of his mo- ther's family have died of the same disease ; and all of his brothers and sisters, without an exception, have in early childhood been suf- ferers from enlargement of tonsils and ulcerated sore throat. He is now the picture of health. Case III. — A mulatto girl, belonging to Mr. W. D. T., aged four years. This was a case of congenital asthma. The symptoms in this and the following case (aged about four years) were so similar to those of Case I. that I shall not describe them. The treatment was nitric acid, three drops three times daily in a wineglass of sugared water. This case resisted the treatment rather longer than the other cases, but was cured in about six weeks. In Case IV., the immediate effects of the acid were perceived in a few days ; and in eight or ten days she was cured. Case V. — I never saw. It was a negro girl belonging to Mr. C. of Camden county. She was seven years of age. Her master applied to me for a prescription, afrer giving some of the most prominent symptoms, which convinced me that the case was asthma, as he de- clared it to be. I prescribed five drops of nitric acid three times daily. I heard nothing more of this case for several months after I had prescribed, when I was informed by her master that she was well. A sufficient time has elapsed, in all these cases, to convince me that they have been radically cured. Should you deem the above remarks and cases worthy a place in your valuable journal, you will please to insert them. It is at least something new in the treatment of asthma. — Amer. Jour. Med. Science. The " Mange" communicated to three Persons by a Pig. REPORTED By H. R. CASEY, M. D., OF COLUMBIA COUNTY, GEORGIA. ^ I will give you the particulars of a conversation held a few days since with a gentleman of this county, and if the deduction I have drawn from the facts as reported is correct, we have presented to us (so far at least as my observation extends) a new disease of the cuta- neous system — one hitherto undescribed by dermatologists. MANGE. 53 Mr. S. asked me " if I had ever known a man to have the mange ?" To which I gave a negative reply : having always understood that it was a disease peculiar to the quadruped. He then asked me "if I thought it possible for a man to catch it from a hog?" I replied, that there are a great many things regarded as impossible, which are not found to be so when subjected to the test — and that this might be one of the cases. He then proceeded to give me the following particulars : He states that about the 1st of May last, having a pig badly dis- eased with the mange, and being desirous to cure him, he had some soap and water got and went to work on him with his hands — and that after giving him a good washing, he stripped him almost of his entire external with his nails. That he was entirely well at this time ; but that in about three hours thereafter, he felt an itching on his hands and wrists, and an eruption which commenced spreading upwards ; that about the same time his ankles began to itch him and the eruption there made its appearance, which also spread upwards and met the eruption from above at the half-way house — the umbilicus ; that it reached its height in about two weeks ; that the eruption was charac- terized by great heat and intolerable itching, composed of small vesi- cles, which, though not confluent, stood close together over his entire tegumentary tissue. Thus was he at the time of his commencement with the ablution — a sound and healthy man — but in a very short time thereafter, he was transformed into a Lazarus. He thought he had contracted his disease from the pig, and went to work to cure himself, using first the soap and water. This not benefitting him, he was bled and took salts. This failing, he tried pot-liquor — then the grease from fried bacon — then a solution of blue-stone. He does not think that any of the means used had any control whatever over the disease, but that it seemed to pursue its course, knowing no conqueror, until it finally wore itself out in about five weeks. Now, from the above narrative, I can but infer that the disease in question was one identical with the mange, and that it was communi- cated from the quadruped to the man. And I am further strengthened in this view of the case, from the fact — that a female and the negro boy who held the pig while being subjected to treatment, became in like manner affected. The view I have taken of this case, I know to be in direct conflict with the long-established dogmas of the veterinary school, but I think I am sustained in my position from the facts of the case — and " facts are stubborn things." By reference to the " History of the Horse," I find the following language. The author, in speaking of the contagiousness of the mange, goes on to say — " If the same brush or curry-comb be used on all the horses, the propagation of mange is assured ; and horses feeding in the same pasture with mangy ones, rarely escape, from the propensity they have to nibble one another. Mange in cattle has been propagated to the horse — and from the horse to cattle — but there is no authenticated instance of the same disease being communicated from the dog to the horse. There is as much difference in the character and eruption of mange in the horse and dog, as between either of them and the itch in the human subject ; and the itch has never been communicated to the quadruped, nor the mange of the quadruped to the human being." 54 REMEDY FOR QUACKERY. My only reply to the above quotation, is the presentation of the case related ; and if I am not sustained in my corollary from the facts of the case, this article will go for nothing. I pretend to no familiarity with cutaneous diseases; but "if I were called, upon to classify the mange, I should locate it in the group dermatoses scabienses of Wilson, not only from the pathology, but also from the therapeia of the dis- ease ; for I find sulphur the anchor of safety to the veterinary surgeon. Nor do I think there is anything very strange in all this ; and the only reason why we have never before had the mange communicated to man arises simply, I think, from the fact, that in all probability more caution has hitherto been experienced than was in the case before us. We have examples of other diseases occurring in the human subject, the result of propagation from the lower order of animals. In the Revue Medicale of July 1845, we have detailed a case of an officer who took the glanders and farcy from a horse, and in which experi- ments were made by M. Andouard, to test the contagiousness of the human fluid introduced into other animals — the results of which ex- periments went to prove that the disease was not only communicable to man from the horse, but that the disease was again transmissible from the human subject to the quadruped. In the Southern Medical and Surgical Journal, November 1847, we have a case of glanders in the human subject, derived from the horse, reported as occurring in your own city. Other -diseases might be mentioned occurring in the great paragon of animals, communicated from the lower order ; but I have already spun out this article to a greater length than was designed at its commencement, and will conclude by merely advising those persons who may have to treat the mange in stock to touch it lightly, and never make a curry-comb of their hands ; to which in- junction I know my friend F. will say, Amen. [South. Med. and Surg. Journal. Remedy for Quackery. In the October number of the New Hampshire Journal of Medicine is an article by Dr. Garland on a proposed "Remedy for Quackery." It is decidedly our opinion, that if the measure were adopted which is recommended by the writer of the article in question, the profession might be most emphatically placed in the same category with the class of whom they complain. Oftentimes, no doubt, when the minds of our patients are diseased, the exhibition of a placebo is attended with better effect than that of remedies more potent ; yet to make a general practice of giving pleasant or inerl preparations in form of medicines, because the patient wishes it, and would otherwise obtain that kind of remedies from the vaunting quack, would not speak well for the purity of medical science. If we wish people to free them- selves from the abominable habit of continually taking something in the shape of medicine, and particularly from those whose only claim to medical skill is their own boasting, we should endeavor to enlighten our patients, by explaining to them the laws which govern life, and DOCTORING BY THE YEAR. 55 so much of pathology as would intimidate them from using remedies intended to cure a multiplicity of diseases. " A little learning" is not always " a dangerous thing." It was said of Frere Jacques, the natural cutter for stone in the bladder, that when the anatomy of the parts was taught him, he saw at once the danger to which his patients had been exposed, and was deterred from performing lithotomy ever afterwards. He had not the moral, courage to attempt an operation when fully informed of the danger to the life of his patient, though previously he had done so with the utmost sang-froid and with average success, exciting the astonishment and admiration of the crowned heads and many of the surgeons of Europe. In our own day are some who ranked, until a certain period, as the very best in diagnosis and prognosis ; but when the great continental pathologist gave a key, whereby functional and organic disturbance could easily and readily be detected by physical explorations, they were in a great measure despoiled of their old tact in detecting disease. The latter illustration may be considered irrelevant to the subject under discussion ; yet it has a bearing upon it. We contend, that if our patients are taught a certain amount of knowledge respecting themselves, they will be less likely to attempt to cure their own diseases, or place the least con- fidence in the boastful quack or his medicines. If we know the prin- ciples and practices of quackery to be fallacious and mercenary, would it be the part of wisdom in us to place ourselves on a level with quacks, by practising their schemes to get patients and make them take our medicines? There is a way to abate the evil com- plained of; the profession themselves are in a great measure to blame for its existence. When they possess the proper qualifications and take the right means to combat the hydra monster, their cause for com- plaint will be very much lessened. — Boston Med. fy Surg. Journal. Doctoring by the Year. Some years since, it was my lot to reside, for a time, in a remote and frontier region of our country, and among a French population of some thousand of inhabitants, remarkable for their simplicity and primitive manners, and exceedingly ignorant upon almost all subjects, and especially so upon medical matters. Indeed there had never been a physician located among them previously to my arrival. About a year before I came into the country, it had been visited by a quack, who called himself Dr. L — y, and who contrived to obtain for himself a considerable practice, and for a short time quite a reputation. From all I could learn of him he was in the habit of using but two remedies, tartar emetic and blisters. It was said that he had obtained the anti- mony and cantharides from the wreck of a vessel on the coast — these two articles being almost the only ones saved from it. Be that as it may, he soon obtained practice with them, and was employed by se- veral families to attend them by the year. A simple-minded French- man, in moderate circumstances, from whom I obtained the following 56 BATHING. account, told me that he thought he would also try the doctor for a year, and accordingly made a bargain with him to that effect. At the expiration of that time the doctor called for his money, which our friend Jose tendered him according to agreement, but at the same time remarked, that it was rather hard to be obliged to pay it, as neither himself or family had been sick. As, however, he felt very reluctant to pay out his money without receiving some benefit from it, he told the doctor he thought his system was in want of medicine; and on enquiry of the doctor as to his symptoms, he told him, that " somehow or other, he couldn't eat as much as usual, felt unusually sleepy at times," and requested the doctor to feel his pulse, look at his tongue, &c. The doctor, after examining into the case, prescribed for him about twenty powders of tartar emetic, four grains each, and told him to begin next morning with the powders, taking thern at intervals of a few minutes ; but that as it was necessary to take away all his bile, he must assist the vomiting by large draughts of warm water, so as to scour all out and make a clean house of it. Jose therefore went to work the next day, by heating two huge brass kettles of water — said kettles being generally used for scalding hogs. The water being ready, he then set to work in earnest with the powders, taking them in rapid succession. They soon produced severe vomiting. Jose drinking, at the same time, enormous quantities of warm water, till he had used up nearly all in the kettles. By this time, he was so pros- trated with almost incessant vomiting, that his friends became alarmed, and sent for the doctor. He instantly applied a blister, of vast size, covering almost the whole of the abdomen. On calling to see him next day, he found Jose propped up in bed, and looking quite pale and interesting. Under the blistered cuticle, was an immense collec- tion of serum, laying like a great bag on his belly. He asked Jose if he was not now convinced that he had got rid of his bile, and got. the worth of his money, or if he wanted some more medicine? "Ah, mon dieu," says Jose, holding up his hands, " I want no more dam medicine, nevare. I am perfectly satisfied! " — Exchange paper. BATHING. A writer in the Boston Medical and Surgical Journal utters the opinion that "once a week is often enough to bathe the whole body for the purpose of luxury or cleanliness. Beyond this we consider bathing as injurious. Flannel worn next to the skin at all seasons is proper, and infinitely more healthful than all the daily baths now so fashionable. " The argument by which this opinion is supported is as follows : " The oil which is secreted by the sebaceous glands of the skin serves the purpose of lubricating its surface. Now, if this secretion is con- TRANSACTIONS OF AMERICAN MEDICAL ASSOCIATION. 57 stantly removed as fast as exuded, its destined object is thereby de- feated. The excretory ducts of the perspiratory glands themselves require this unctuous matter of the skin to keep them in action. If very frequent bathing of the body is practised, it must be obvious that this matter cannot be long present to perform its office. As to the as- similations of functions of the skin and lungs, it will be apparent that when the skin acts imperfectly, or ceases to act at all, the lungs have an extra amount of duty to perform ; and it is generally in just such cases that engorgement of them takes place, constituting inflammation or pneumonia." Transactions of the American Medical Association — Vols. I. and II. The October number of the British and Foreign Medico- Chirurgical Review devotes eleven pages to these two volumes, and, as might have been expected, handles them in rather a cool manner. The following is the commencement of the review : " These 'Transactions' are the chronicles of the proceedings of the first two annual meetings of the American medical association, form- ing two goodly volumes, the contents of which have little resemblance to those bearing a similar title in this country. It is true, the advance- ment of medical science is the ultimate object of publication in both cases ; but the efforts of our trans-atlantic brethren to this end are as yet but in a comparatively early stage of development. In a country in which medical education, practice and literature are in so inferior a condition as they at present hold in the United States, the earliest efforts of the lovers of science must necessarily be employed in exam- ining the cause of, and devising the remedies for, so lamentable a state of things. This work the association has undertaken with courage and ability ; and a large portion of the present volumes is taken up with an account of the results of their enquiries, and a detail of their suggestions. Already the National medical convention, which organ- ized the present medical association, had published a code of medical ethics, which met with much approbation both in America and Europe, and formed a fitting preliminary to more extended operations. The association is composed of delegates of medical societies, colleges, hospitals, lunatic asylums, and other institutions from all parts of the Union, and holds its meetings at different cities in succession, after the manner of the British association for the advancement of science. The two meetings which have taken place at Baltimore and Boston were attended by several hundreds, comprising a great number of pro- fessional names of eminence. The two volumes now before us, con- taining an account of their proceedings, are chiefly filled with reports given in by the respective committees upon the present condition and future prospects of the profession, and upon the progress of medical science. Some of these are well deserving of notice." 58 STATE INSTITUTIONS. Then the "report of the committee on medical education" is no- ticed, and the defects of our whole system of teaching and licensing are very justly exposed. The opinion of the committee, "that most of our physicians are fully equal, and in many respects far superior, to the general practitioners of England," is flatly denied. A long notice of the " report on medical literature," then follows. The envy of our ability to diffuse all sorts of literature, and make re- publications of foreign works, at a much cheaper rate than the English can, is palpable ; and the reviewer, of course, congratulates himself upon the petitioning of Congress to pass an international copyright act, by our association. After noticing and extracting from several of the practical reports of the committees, the review closes thus : " In concluding our notice of these volumes, although approving of the general tone and spirit (save as to the exceptions we have men- tioned) which have prevailed among those engaged in assembling the materials, we must be allowed to observe, that, if the medical associ- ation is ambitious of assuming a position among the various scientific bodies that issue their memoirs and transactions in Europe, a very different class of literary productions must be looked for at their hands. They must not content themselves with merely recapitulating in reports and retrospects what has already been published — a work that might be accomplished by a far less massive organization — but must themselves largely contribute to the general stock the results of experience and the fruits of meditation." LUNATIC ASYLUMS OF VIRGINIA. By the executive reports from these institutions, it appears that " they have never exhibited a more gratifying aspect to the friends of hu- manity than at present." The reports of the physicians contain many interesting tables of physiological and other facts, but our room will only allow us to make the following extracts : " The number of patients who have been inmates of the Eastern Lunatic Asylum since the 30th of September 1849, is two hundred and thirty-four. Of these, one hundred and forty-five were males and eighty-nine females. " The number of patients on the 1st of October 1849, was one hun- dred and eighty-one, viz : one hundred and seven males and seventy- four females. " Since the 30th of September 1849, fifty-three have been received ; thirty-eight of these wTere males and fifteen females. " The number of discharges is eighteen, viz : eleven males and seven females. One male patient eloped. STATE INSTITUTIONS. 59 " The number of deaths is twenty-two, eighteen males and four fe- males. " The number of patients nt present is one hundred and ninety- three, viz : one hundred and fifteen males and seventy-eight females." Civil Condition of Patients in the Asylum from January 1st, 1847, to October 1st, 1850. Single, Married, Widows, Widowers, Ages of Patients in the Asylum September 30, 1850. Below 20 years, From 20 to 30 years, 30 to 40 " ■ 40 to 50 " - 50 to 60 " - 60 to 70 " - 70 to 80 " - Males. Females. Total. 121 50 - Ill 59 64 - 123 0 16 - 16 9 0 - 9 Males. Females. Total. 2 3 5 28 6 34 26 16 42 28 32 60 17 16 33 14 3 17 0 2 2 115 78 193 WESTERN ASYLUM AT STAUNTON, VA. Within the year just closed, there have been accommodated in the asylum three hundred and forty-eight patients, of whom two hundred and one were males and one hundred and forty-seven females. Of these, two hundred and sixteen occupied apartments here at the com- mencement of the year, viz : One hundred and twenty-one males and ninety-five females. One hundred and thirty-two were admitted du- ring the year, of whom eighty were males and fifty-two females. Within the same period there were discharged, - 73 Of these, had recovered, 45 " " were much improved, - 4 " " " improved, - 2 " " " unimproved, - 2 " " eloped, - 1 " " died, 19 — 73 60 STATE INSTITUTIONS. Tabic shewing the Civil Condition of Patients who have been in the Asylum during the ijear. Married, Single, Widows, Widowers, Unascertained, Males. Females. Total 63 58 121 123 72 195 0 16 16 7 0 7 8 1 9 201 147 348 PENITENTIARY OF VIRGINIA. It appears by the annual report of the surgeon of this institution, that during the twelve months, ending October 1st, 1850, there have been treated 515 cases of 71 diseases, injuries, &c. — of these, 110 were of diarrhoea, 54 biliary derangement, etc. Of these cases 22 were fatal — 9 consumption — 6 scrofula — 4 bowel complaints — 2 typhoid fever and dropsy — 1 tetanus. Death has made sad ravages with the medical profession in Cali- fornia. During a fortnight, the following physicians were swept off by cholera : Drs. Cobb, Whitlock, Noble, Mason, Yearly, Robert Mc- Namer, Green, Stansbury, Holmes, Metcalf, H. P. Hess, G. W. Held, and Barnes. — Newspaper. CORRESPONDENTS. 61 TO CORRESPONDENTS. Articles intended for publication should be received by the 10th of the month, at least, and must only be written on one side of the page. As printers are unacquainted with the technical language of medical men, it is very desirable that the manuscript should be clear, written out fully in a legible hand, and proper names ought to be in square letters. Correspondents will always send their names to the editor ; when it is desirable they will be kept strictly confidential. Any disposition will be made of manuscripts desired by the author. The short time in which we had to establish this journal rendered a circular necessary. In sending out these circulars, the postage of many of them was not paid, and for fear that it may have given um- brage to others — as we know it has to two — the editor feels it due to himself to explain why the postage of all was not paid. In the first place, he was embarking in an enterprise of great interest to every member of the profession, and one in which he only could be the loser. The pittance on each circular could not be felt by any physi- cian, but the postage on them all would have amounted to $ 100. This, though a most useless and heavy expense, would have been in- curred, had there been a certainty that his directions were correct. But of the list of some 2000 or 3000 names which we obtained, there were only a very small number with the post offices attached ; many of the names were of persons not belonging to the profession, of dead men, or those who had removed ; generally only the county was put down. Whenever it could be done, the budgets for the counties were sent by private hands, or given to a countryman for direction, and they found their way into the mail. Two only of the 2000 have not been deemed worthy of their postage ; and — particularly when the above reasons are taken into consideration — we hope there are no others who can blame us for not having paid postage on letters which we were not sure would ever get farther than to a county C. H. post office. Should there be, however, we will anxiously wait an oppor- tunity of repaying them the half-dime grievance, with full and liberal interest. — ^ T, MIC AN NI>, YA. Pima® ram. In the department of MEDICAL LITERATURE, they devote particular attention in keeping up a full supply of the Standard Works, as well as the late publications, and offer them for sale as low as they can be had in any regular establishment in the United States. They furnish all the Medical Periodicals. 13*° English, French and German Books imported to order, with care and despatch. (LATE DRINKER & MORRIS,) I Wholesale Booksellers, Stationers, Publishers, and Dealers in Piano Fortes, Mirsio, Mnsical Merchandise, Fancy G-oods, See, 8to. 97 MAIN STREET, RICHMOND, VA., _ Arc constantly supplied with the most important publications in every department of literature, the arts and sciences. Orders from private individuals, schools, colleges, academics, semi- naries of learning, or other public institutions for Boolcs, Stationery, Piano Fortes, &fc, &fc, will be furnished on the most favorable terms, and with the greatest despatch. Foreign books imported to order. ole agents for the sale of Worcester? uperioritv beg to sub- Morris & Brother are tl unrivalled Instrument?., and in evidence of their mit to a discriminating public the following testimonial Improvement in- Pianos. — New York is fully entitled to the credit of ha%ing effected the greatest real improvements in the construction of that noblest of all instruments, the Piano. Some others may have added to the sweetness of certain parts of their instruments at the cost of the power arsd brilliancy of the whole; while others again have lavished money upon the fantistic decorations of the frames; but to our fellow-citizen Worcester, whose Pianos have latterly made way so rapidly into jrablic favor, belongs the merit oi' increasing at the same time the power, quality and endurance of tone, aiid without a corresponding exaggeration of price. — New York Mirror THE AND VIRGINIA MEDICAL GAZETTE. No. 2. RICHMOND, FEBRUARY 1851. [VoLL An Abstract of an Essay on Congestive Fever. BY A. T. B. MERRITT, M. D., OF RICHMOND. [Read before the Medical Society of Virginia, December 1850.] After a medico-topographical outline of some sections of our coun- try, and some general pathological remarks — Dr. Merritt proceeded to say, that the most malignant and un- manageable forms of " congestive fever," improperly so called, which had fallen under his notice and treatment, had been presented to him in Eastern Virginia, during several years, in great abundance and as an epidemic. As a general rule, it is true the tendency of all diseases is to run their course more rapidly in more Southern climates, and therefore no time can safely be lost in administering our remedies; but I have seen at times equal rapidity in their progress in our sec- tion of the Union. At the South, our remedial agencies seem to be followed by as prompt relief as in Virginia, and perhaps recoveries are more rapid, and as entire and satisfactory. I will not detain you by dwelling on the different phases of mias- matic or bilious fever ; or distinguish very critically between its inter- mittent, remittent, or congestive varieties; or speak at length of its malignant, yellow or icteroid form, or its too common typhoid degene- ration, nearly always arising from neglect or maltreatment. I will make no distinction as to the simple or excitive, the inflammatory and congestive varieties of each of these specified fevers, or their degrees of violence, but proceed to describe the congestive fever, very incor- rectly so termed, as I have often seen it prevailing extensively for years together, and attacking large numbers of all ages and condi- tions, and following frequently distinctly marked cases of each of these forms of fever. I have often used the term "congestive," as applied to this fever, which, in different parts of our country, is called by a great variety of names — as cold fever, cold plague, cold chill, congestive chill, con- gestive fever, pernicious fever, typhus fever, typhoid fever, and many 62 MERRITT ON CONGESTIVE FEVER. other names, or rather misnomers. Most of these synonyms seem to me to be singularly inappropriate, founded on no sound pathological views, and to be in fact medico-philological solecisms. Is not the very term congestive fever, as thus applied, an absurdity? Conges- tion is a symptom of morbid action, confined to no class of diseases, and takes place at the close of many, perhaps nearly all, diseases affecting our general system. I have no strong repugnance to using the expression, congestive state of bilious or any other fever, to desig- nate the presence of extensive congestion in such fever. In our fever, as well as in cholera, it is true, there seems to be a great tendency to congestion ; and whenever it does occur in either, it is indeed " con- gestion in earnest." I have often been struck with the close analogy which seems to exist in very bad cases of each of these diseases, presenting many morbid phenomena, nearly allied, I have no doubt, in their nature, as well as in appearances. Some subtile atmospheric degeneration, however produced — some diffusive, penetrating mala- rial poison, however generated and composed, acting on our constitu- tion generally, seems to spend its chief force on the vital and natural organs, leaving less implicated the animal functions. We may there- fore safely conclude that the nervous system and its dependencies, in both of these diseases, feel the chief force or impetus of the morbific causes, and the other systems of our organism becoming involved, are at last overwhelmed in one common ruin, with symptoms, if not identical, at least closely allied and nearly analagous to each other. But I have expressed the opinion, that congestion is only a symp- tom of disease, and not the disease itself — and very often not an essen- tial part or condition in which the other symptoms have their origin, and from which the greatest danger is to be apprehended. The oppo- site opinion has led to many views that are unsound in pathology and unsafe in practice. That temporising treatment of any disease, which looks to the relief of symptoms, must in the main be quite unsatisfac- tory to the enlightened physician, and lead to great want of success at the bedside. The leading secret of successful practice is an unfear- ing and sturdy grapple with the disease itself, and as little remedial application merely to its signs, or its symptoms, as is consistent with the quiet and comfort of suffering humanity. We may rest assured, that in medicine, as in every thing else, the old and long-established maxim — " sublata causa, tollitur effectus" as soon as we remove the cause, the effect and symptoms will cease, is true ; and that in medi- cine especially it is a maxim of inestimable value, and ought to be a cardinal rule with every sound and enlightened physician. I do not believe that congestion in this fever is the chief or princi- pal source of danger. I suppose it will be conceded on all hands, that it is a venous congestion, and this we constantly meet with in many other diseases, with no fatal results. We see it in syncope, in concussion of the brain, in severe surgical operations and violent in- juries, and in every accident and disease inflicting a severe and decided shock on the nervous system ; yet in all these cases it is not the con- gestion, but the great prostration of nervous power, we fear. We rarely find on autopsical examination in fatal cases, congestion enough MERRITT ON CONGESTIVE FEVER. 63 in any organ to account for fatal results, either in such cases, or in the disease under consideration. I cannot attribute to inflammation and its consequences much of the danger and fatality of our disease. I do not for one moment believe that we would observe in purely inflammatory diseases such marked and distinct periodicity, and such obvious and decided intermissions and remissions. I cannot suppose that a degree of inflammatory ac- tion, sufficiently high to lead to a fatal termination, can be so far over- come and extinguished as to be nearly imperceptible to our senses, and the feelings of the sufferers themselves for hours, and then be re-es- tablished and rage for a short time, and disappear again of itself. I cannot believe that inflammation can be thus formed and become dor- mant, and then be rekindled for days, and finally removed by a dose of medicine, and a few grains of quinine. The very supposition is almost monstrous, and post mortem examinations in most cases display little or no inflammation. If these views be at all correct, they are the mere attendants of the disease in some cases, and not the sources of danger and death — the mere casual appendages, and not the disease itself. I believe our disease is primarily and essentially seated in the ner- vous system ; but here it cannot remain long to any extent, without ne- cessarily extending itself, and diffusing its deleterious influences to other systems, and different organs, to the fluids as well as the solids. But to the nervous system we must look for the source of symptoms and danger. On it the malarial poison makes its first impression, and produces a prostration of the nervous power to a greater or less de- gree. The nervous power being diminished or prostrated by this morbid impression, we must look in the first place for its effects on the organic functions, and we soon find them involved in many abnor- mal and irregular actions. The nervous fluid or power being supplied in smaller and lessened quantity or force, we perceive a want of ac- tion in the capillaries and extreme blood vessels, and coldness on the surface. The extreme blood vessels seem to collapse, because they circulate now little blood, and do not receive their due proportion of nervous influence, which is necessary to this as well as every other part of our organism, for the easy and normal performance of its func- tions. The blood enters these extreme arteries on the surface, now in an enfeebled condition, with great difficulty, and circulates through them with a slow and obstructed progress. Hence we observe much shrinking, contraction and paleness on the surface ; and when the blood which passes on reaches the veins, it is there congested or stagnates, and produces the lividness, and finally, in extreme cases of this disease and cholera, the cyanotic appearance so frequently ob- served. The want of due innervation at length becoming extreme, these vessels allow the watery or serous parts of the bloodto escape from them, and we have copious and profuse sweats ; and in cholera, from a similar and perhaps identical condition of the capillaries on the intestinal surface, the serous and other discharges, which we observe in that disease. The great coldness on the surface and in the breath arises from a deficient decarbonization and calorification of the blood 64 MERRITT ON CONGESTIVE FEVER. in the lungs, occasioned by the great general and local irregularity of the circulation. The " function of respiration also suffers from the same deficiency of nervous influence ;" and the circulation of the blood through the pulmonary arteries, being languid and slow, or impeded, the necessary changes for its purification do not take place. We therefore have very often great anxiety and oppression in the chest, difficulty of breathing, and deep and frequent sighing. The sickness of stomach and the inces- sant vomiting and purging must be attributed to the same causes, and we may have these symptoms prevailing to an almost insufferable ex- tent. The distressing sensations experienced in syncope from loss of blood, and in a semi-paralyzed limb, are to be ascribed to a similar want of local innervation. Serous discharges from the bowels may be compared to profuse sweatings from the surface, being evidently analogous in their origin and nature. I will only notice, in addition to these symptoms in this place, the intense thirst and great internal heat of which the sick complain so much and so loudly. It is known to all physicians, that great and most distressing thirst prevails in every dis- ease, and in every condition of disease, where the blood vessels in their capillary extremities are pretty well emptied of their blood, whether this emptiness be brought on by direct loss of blood, or the usual course of this or other diseases. The very frequent sensation of in- ternal and the more rare sensation of external heat, are only examples of deranged sensibility arising from the irregular and anomalous ac- tions of the nervous system from imperfect and deficient innervation. The heart, pulmonary and systemic capillaries, thus suffering from a deficiency of nervous supply, arising from the prostration, in a greater or less degree, of the whole nervous system, we have, of course, accumulations or congestions of blood in the veins and great internal organs, and especially those connected with the portal circulation. This state, modification or species of miasmatic fever often presents itself under the intermittent, remittent, and less frequently, the conti- nued variety. But in such cases as appear to be continued in the com- mencement, the patients surviving, and the disease being partially or wholly unchecked for two or three days, an intermittent or remittent garb is generally assumed, and we have quotidian, but oftener tertian or double tertian paroxysms, the alternate paroxysms being alike, and occurring frequently at different hours of the day, and with varying relative severity. It presents very different and proteiform pheno- mena, depending in a great degree on the direction of its chief attack. I have already said the organic functions were in many cases espe- cially affected, but in not a few subjects the animal seem to be chiefly implicated. In the former, we trace the leading evidences of disease in the organs of digestion, respiration, secretion and circulation ; and in the latter, the brain and muscular system are the prominent suf- ferers. We also find different symptoms more obvious and promi- nent, as this or that organ has the chief impetus of the morbific cause directed against it. The attack is usually preceded by feelings of languor and indispo- sition, giddiness or headache, and pain in the back, but at times it is MERRITT ON CONGESTIVE FEVER. 65 very sudden, and gives little warning of its approach. It may occur at any time of the day, or in the night ; and it may present its severer characters at once, or differ in little or no respect from ordinary mias- matic fevers for days, if, indeed, it is at all different. In particular years, I have seen nearly every case of fever, when neglected or mis- managed, shew a most decided tendency to run rapidly into the form of fever now under discussion ; and I verily believe I have seen more cases of it at times, brought on in this way, than by the force of the morbific causes. A chilly fit or paroxysm, differing in no sensible character from an ordinary intermittent or remittent, often ushers in this disease. The pains in the head, back and limbs ; the frequency, irregularity, and often the weakness of the pulse ; flushes of heat and cold, alternating with slight outbreaks of perspiration ; copious discharges of limpid urine ; slight nausea, and a dull, constricted, inelastic and harsh feel- ing of the surface, continue sometimes for hours, when they are fol- lowed by a re-action or fever more or less complete. This re-action is, however, often short in its duration, and followed by considerable relief from these symptoms. This respite lasts generally till the next day, or the disease may assume the tertian form, when these paroxys- mic symptoms re-appear, and are more severe, and followed by more dangerous phenomena; or these phenomena may be postponed till the disease has continued for several days. In many cases, the re- action is never complete, unless aided by medicine, but the conserva- tive powers of nature continue their efforts, as if tbey desired a full development of open fever. The symptoms, when this imperfect re- action and ataxic state are removed, and the disease fully formed, dis- playing in the organic functions its principal power, may now be suc- cinctly detailed. They of course do not all present themselves at the same time, or in one and the same case, but are generally to be ob- served during its progress more or less in every attack. The pulse, though sometimes strong, frequent, laboring and irregu- lar, is generally quite small, quick, feeble, frequent and irregular, and not unfrequently fluttering, thread-like and intermitting. The number of pulsations in a minute vary from 110 to 160, or even more, and of course incalculable, though I have seen the pulse very weak, feeble and fluttering, and not frequent in a few cases. In a few cases it is not to be felt at all at the wrists, while the heart and carotid arteries beat rather violently. During the partial intermission or remission, the number of pulsations is lessened, and the volume and force of the arteries increased; but unless we now resort to prompt remedies, in order to avert the next paroxysm, the pulse each time becomes more frequent, feeble and irregular, until it entirely disappears. The stomach is often extremely irritable, and throws up everything which is swallowed, very soon after it reaches its cavity. This is a most distressing symptom; and the vomiting being often very violent, with much retching, is accompanied by great tenderness and some- times pain in the epigastric region. The matter thrown up is some- times bilious, but oftener what has been swallowed, or a mucous or muco-serous fluid, occasionally tinged with blood. The bowels are 66 MERRITT ON CONGESTIVE FEVER. generally, but by no means always, confined, and when moved, their contents appear unhealthy and offensive, but are sometimes wa- tery and tinged with blood, fetid, and resemble the water in which fresh meat has been washed. The respiration is very much altered, and accompanied by continued sighing in many cases. It is often " hurried, irregular and panting," and the patient complains of much " difficulty in getting his breath," and requires constant fanning, and desires every moment the accession of fresh air. Towards the close of the disease, the number of inspirations is generally greatly in- creased, but I have seen it in a few cases much diminished. The tongue is sometimes nearly natural in appearance, but it very seldom remains so long. At other times it is pale, cold, and covered with a whitish coat, which frequently becomes much thicker and darker, and brown, or brownish in the middle or over its whole dorsum. The mouth soon becomes full of a thick, tenacious secretion, and the teeth covered over with a dark sordes. The tongue and mouth, however, often become very dry, and sometimes quite red and glazed, many papillae appearing on the surface of the former in the last stage of the disease. The skin presents in many cases a most marked aspect. The hands, feet and face are pale ; the features sharp and shrunk, strongly expressive of uneasiness and alarm, which the patient does not appear really to feel. The eyes are bright, and sometimes very clear and brilliant, but after a while seem to sink in their sockets. Their membranes are sometimes slightly inflamed, secrete a thin fluid, and at last throw off a thick purulent matter, rather copiously. I have, in two cases, seen the whole eye altered in color, and the hu- mors very opaque and milk-like in their appearance, accompanied by total blindness, and a dead and shrunken appearance of the balls for several days. I feared at the time one of these patients, a little boy, would never recover his sight ; but his eyes, at once so discolored and collapsed, were at length fully restored. The general surface is cold and shrivelled, and after the sweating has continued for hours, the hands, feet and legs are like these parts in patients dying of cholera, or the hands and arms of a washer-woman. The patient, in this cold state, often complains of great and most distressing internal heat, and will bear no bed clothes. The thirst is a most striking symptom, and often very oppressive. The patient is continually crying out for water, and can never be satisfied, and whatever he swallows is returned very soon, even the little water from a melted pellet of ice. I have often been told by such sufferers, that they would swallow water, even if convinced it would kill them, so great and uncontrollable is the desire for it. The secretions from the liver and kidneys are either very small, or suspended, and the same may be said of the secretions of the stomach and bowels in many cases. The hiccough is sometimes very distress- ing, and I have seen the patient nearly convulsed by it, the bed vio- lently shaken, and heard it at a distance of 200 yards. Along with these symptoms we have many others, the most prominent of which are, great restlessness and constant jactitation, an inability to lie in the same posture a moment, continual change of position, a moving from MERRITT ON CONGESTIVE FEVER. 67 bed to bed, or from room to room, a perfect unconsciousness of danger; and when asked how he feels, the patient will often tell you " he is very well," and laugh at you when you tell him he is ill and must take medicine. The sick will at times walk about their rooms after they have lost their pulse, retaining in a great degree their muscular powers. The mind is often clear and unclouded nearly the whole course of the disease. While the skin is generally cold, there is often warmth about the forehead, breast, stomach and heart, and in some cases I have observed spasms in the thighs and legs. Deafness and haemorrhages are not uncommon, and general convulsions have occa- sionally occurred. When the disease directs its chief force to the animal functions we have a different set of phenomena. Perhaps a slight chill is succeeded by drowsiness, the patient becoming in a short time comatose, and then stupid, so that he cannot be roused. The breathing is slow and stertorous ; the pulse is usually full and accelerated in some degree, but sometimes very slow. In children this form of the disease is often accompanied by convulsions, and I have often, in adults, seen the co- matose symptoms disappear in the remission and return with the pa- roxysm for several days. I might here add other symptoms, and trace those enumerated more fully, but perhaps I have said enough on this part of the subject. I will now hasten to the treatment of this disease which I have found most successful. I can, perhaps, accomplish this object more clearly and satisfactorily, by giving a few cases, and their management, than in any other way, and conclude by some general remarks. Unfortu- nately for our profession, and more unfortunately for our patients, the ordinary treatment of febrile diseases is too often a temporising alle- viation of symptoms, or a remedial address to the phenomena, and not to the disease itself. Let us recur to the treatment, for instance, of a well defined case of bilious fever, with distinct and well marked tertian paroxysms, as it is frequently seen, and we find decided heat on the surface, activity of the pulse, torpor in the secretory organs, and the usual febrile symptoms after a chill. We perhaps bleed, and give a mercurial cathartic, which brings off bilious discharges with much relief. The next exacerbation approaches, is rather milder, and a similar course is pursued, and attended by similar re- sults. After several chills and fevers, the sulphate of quinine, or some tonic, is used, and the patient recovers, but is weak, emaciated, pale and anaemic in appearance, and we are told we were obliged to half kill our patient in order to cure him. This I have long considered one of the opprobria of medical science. But we have a more violent case, and after pursuing the above or some analogous practice for several days, it is true the fever is subdued, but too often the patient has departed with it. We look too much therapeutically to the symptoms, and use many other remedies in such cases, but our views of pathology are too confined, and our remedial applications quite too restricted. In the remission we have the most suitable time to combat the disease, and by such management we lose the first and most valuable moments, and our patients too often by such mis- 68 MERRITT ON CONGESTIVE FEVER. management become typhoid or die. Let us, therefore, examine well into the pathology of disease, analyse its ravages on all the dif- ferent systems of our organism, address our remedies to the disease itself, and thus protect and save our patients, and adjust all the balances of the different organs. Sept. 27th, 1832. I was called to see Mr. T. A., a wealthy and intelligent gentleman, of good constitution, and about thirty years of age. He had been sick about six days, and had taken several cathar- tics and other remedies. His face was pale and sharpened, his coun- tenance anxious, his extremities cold, and his whole surface covered with a copious perspiration. The pulse was weak, small and irregu- lar, and about 135 in the minute, with great sickness at the stomach and frequent vomiting of a muco-serous fluid. The headache, dis- tressing at first, had disappeared ; delirium last night ; tongue covered with a thickish white coat ; mouth and fauces dry ; thirst insatiable ; great restlessness ; sighing and jactitation ; hurried respiration ; no sleep for several nights ; shrivelled* and corrugated skin on the ex- tremities ; heat on the forehead and epigastric region, and a deficient secretion of urine, were some of the other symptoms. The pur- gatives had produced debilitating, watery evacuations, with little or no bile, and he had been in this state of collapse some fifteen hours. This case I consider a very fair specimen of very numerous cases that occurred, which were generally followed by fatal results in two or three days, unless promptly treated and relieved. The indications of cure were here, according to my views, an alteration of the secre- tions of the stomach, bowels, liver and kidneys, a determination to the surface, and a protection against the next paroxysm. To accom- plish these ends I gave him cal. 12 grains, opium l£ grain, and Dov. pow. 3 grains ; applied a large blister plaster, six by eight inches, over the stomach, and ordered the free use of the sulphate of quinine in four hours. I desired the action of the medicine and plaster to begin to bring the system under their influence before the use of the quinine was commenced. In a few hours he was composed, the sweating nearly arrested, the thirst, sickness of the stomach, and other distressing symptoms gone, and he, to use his own expression, " never felt so much relief in so short a time." The quinine was given in large quantity or doses, and sinapisms, with some warm stimulating drink, administered before the time of the next paroxysm, the next day, wholly averted it. He recovered at once, without one untoward appearance, and has enjoyed fine health ever since this attack. Some weeks since, in a conversation with me, he alluded to this attack of disease, and spoke of his relief as almost immediate and most surprising. Sept. 2, 1826. I saw in consultation Col. , a strong, healthy and athletic man, about 32 years of age. He was very much in the same situation as the preceding patient ; had been sick seven days, and the perspiration had continued some time longer. I recommended an immediate resort to the above course of treatment and decided sti- mulation. The delirium being considerable and having lasted for some time, fears were entertained of the use of opium and stimula- MERRITT ON CONGESTIVE FEVER. 69 tion. I urged the absolute necessity of bold measures to fortify the patient against the next paroxysm, under which I was sure he would irretrievably sink, if it approached before he was under the influence of this or some similar course. T could not prevail on him to use my remedies, and left. He used blisters, sinapisms and very mild tonics ; and on the night of the 7th of September, I was called again to see this gentleman, and found him unprotected for the approaching paroxysm at 10 o'clock on the 8th, and now there was no time to accomplish his safety by these remedies. The paroxysm anticipated, and the patient never rallied, but died soon, presenting the wrinkled and blue appear- ance and copious perspiration of those who die of cholera. I have always thought that the same treatment, applied perseveringly and faithfully, would have been attended with the results of the first case. I am much strengthened in my opinion, by my general experience, that nearly all similar cases treated as I have suggested, recovered, and almost all of those which were not, resulted fatally. Oct. 27, 1826. I was called as consulting physician to see Mr. , a wealthy and most intelligent gentleman, about 26 years of age. He was very cold, with a weak, small, fluttering, and at times nearly imperceptible pulse, 147 or 148 in the minute. There was great cold- ness on the surface, with slight and unequal perspirations, confined mostly to the forehead ; great restlessness and jactitation and thirst, hurried and sighing respiration, the tongue slightly furred and dry, the stomach extremely irritable, and rejecting everything, and much anxiety of countenance, and bright and brilliant eyes. He had been treated for several days by purgatives and the usual remedies. The purgatives had not brought away much bilious matter, but thin, wa- tery and debilitating discharges. There was slight delirium, and he had been in his present condition twenty-four hours. The purgative plan had been continued to the time I saw him, and only two hours before he had taken a full dose of calomel. He was now using the close-stool every fifteen or twenty minutes, and all that passed from him was a small quantity of thick secretions very much resembling indigo mud, not exceeding a half teaspoonful at a time — and often no- thing but flatus. I suggested an entire change of treatment, and immediate resort to opiates, with extensive blisterings, sinapisms, and free and continued stimulation, and then tonics and alteratives. I remarked, that without improvement, life could last only 24 or 36 hours ; that the plan of treatment now in trial had been urged sufficiently, and had made no salutary impression whatever on the disease, and would be fatal to a certainty if pursued any farther ; and that the only hope of success arose from the opposite plan of treatment, suggested by me. After a long argument and animated discussion it was agreed, that I might try my treatment till morning, if I would stay all night with the patient. I immediately gave an opiate alone, as he had already taken a full dose of calomel, applied a very large blister and sinapisms, and commenced on moderate doses of quinine, — for I had not yet learned the value of large doses, — and the free use of old rum, three pints of which were given in 15 hours. In a few hours, he became more quiet ; 10 70 MERRITT ON CONGESTIVE FEVER. had for three or four days no more motions from his bowels, and his pulse by morning was increased in volume, and reduced to 138 or 140 in the minute. This course of treatment was now continued, and he gradually improved, the paroxysms being each rather slighter than the preceding, and in four or five days, having thrown in, as I could see a safe opportunity, small doses of calomel or blue mass, with the opium and quinine, dark colored and satisfactory secretions were taking place in the bowels and liver, and warmth was restored to his surface. The improvement was now steady and uninterrupted, and no further difficulty occurred in this most awful case of " conges- tive fever." Similar cases were presented almost every day ; and I will here remark, that although within my practice and observation in the earlier part of this sickly season, such cases were too often fatal, I found, on instituting the above specified treatment, little difficulty in controlling their violence or depriving them of their danger. Here permit me also to remark, that in many cases like the preceding, so prostrated were the powers of the system, and so low the action in the capillary vessels, that purgatives the most powerful, and even the most drastic combinations, repeated over and over, would produce no cathartic operations. However we may classify and arrange medi- cines, as cathartics, emetics or sudorifics, ample and abundant expe- rience proves most clearly, that they act as such only in certain condi- tions of the animal economy ; and we often find, especially in this con- gestive state of the system, and its cognate conditions, that these medicines will not act in accordance with this arrangement and classi- fication. The vital energies are so low, and the action of the capillary- vessels of the skin, and secretory surface of the stomach, and intesti- nal canal, and the glandular apparatus of the liver, and other abdomi- nal viscera so prostrated by the malarial poison, that these remedies lose their usual and appropriate force. Many articles of the materia medica, in large and repeated doses, and in powerful combinations, fail wholly to produce their usual effects in this abnormal condition ; blisters and sinapisms are unnoticed by the sick, mercurials cease to salivate, emetics compose the stomach, and purgatives are followed by no action from the bowels. These things were very common within my notice. But when this state of disarray and disaster did occur, it could be very easily removed generally by a change of remedial strategy. The opium and mercurials, the sulphate of quinine and stimulants, the sinapisms and blisters, combined and used cotemporaneously and per sever ingly , as I have recommended, nearly always, even in very bad cases, would rouse up and increase the nervous energy, sheath and shield the nervous system from further morbific action, determine to the surface, and alter and restore all the secretions ; and in most cases a thick and consistent, and frequently a dark and tar-like and copious secretion from the bowels, a sure harbinger of safety and recovery, would ensue in 18 or 36 hours. I did not rely on these remedies se- parately, for they would thus surely fail very often. The opium and mercurials, and other remedies, will bring on temporary relief and warmth, and improve the action on the surface, but without the blis- ters and sinapisms we had no guaranty of their remaining. The blisters, MERRITT ON CONGESTIVE FEVER. 71 sinapisms and diffusible stimulants would produce warmth and tran- sient reaction ; but without the opium, calomel and quinine, we had no surety that innervation would become regular and normal, the secre- tions be restored, and all these changes and this improvement remain. I am aware much is gained by any of these remedies separately, but to fail in applying the others is to encounter danger, and often death, most unnecessarily and reprehensibly . Sept. 18th, 1832. I was called to attend Mr. B. M., about 10 o'clock at night, a strong, healthy and muscular man, who had been nine days under the management of a Thompsonian. He was in a state of collapse, and had rested none for nine days and nights. His sweating, thirst and restlessness were extreme. He was lying with his head and shoulders about the middle of his bed, and his buttocks and lower extremities in chairs, with a servant fanning him. His breathing was hurried, sighing and short, his surface and extremities cold, tongue brownish and dry, his skin seemed corrugated and close- ly stuck to the bones at the wrists. He was so restless, that he would move from his bed to the floor, and roll over it, and was talking, call- ing and groaning all night. He had been under the influence of Thompsonian remedies nine days, and had a chill or exacerbation daily. I gave him at once a full dose of opium, mild chloride of mer- cury, and Dover's powder, and ordered him to be placed in bed, and everything to be kept quiet, so that he should by no means be dis- turbed under the first influence of the opium. I also applied a very large blister to his epigastrium, and ordered large doses of quinine at 4 or 5 o'clock, and sooner if he should be awake. He rested so well, that his wife informed me she approached his bed three times very quietly during the night, and placed her ear to his mouth, to see if he was breathing. He was so very still, she feared he was dead. The quinine prevented any more chills ; but on the evening of the 19th he had a considerable reaction. I moved his bowels with an enema, the stool being large, dark and thick. At bed-time I repeated the ano- dyne mercurial, and ordered the quinine freely next morning. The reaction was now decided, and rather high, and I repeated the opium and calomel and Dover's powder for two nights, and continued to give the sulph. of quinine to destroy all the remains of periodicity. His convalescence was now rapid, and his recovery complete. In August 1829, Mr. M. was thrown from his sulky, and had both bones of his leg broken. I was his physician, but being on a visit to Southampton court, or at least out of my range of practice, Dr. B. was called to see him. He set his leg and bled him, and used freely cold water to his limb, and administered saline cathartics, and ma- naged his case for two or three weeks. He was in a paludal district, with a highly miasmatic atmosphere, and was attacked with the au- tumnal fever. Finding his case becoming very critical, he was moved to his own residence, and I was called to see him on the 5th of Sep- tember. He was cool, and his pulse weak, frequent and fretful, his alvine evacuations thin and watery, and his condition verging rapidly to congestion and collapse. I proposed at once to give quinine and my usual remedies. No objection was made by Dr. B., and I left 72 MERRITT ON CONGESTIVE FEVER. the patient, fully persuaded all things would soon be right. On my next visit I found, instead of the course suggested, which I supposed would have been faithfully pursued, some drastic compound purga- tive pills had been given every two hours, and that the patient was in the worst possible state of congestion. His surface was cold, his stomach irritable and rejecting everything, his pulse very small, weak and fluttering, and from 155 to 160 in the minute, his voice altered, his countenance haggard and anxious, his delirium constant, his rest- lessness and jactitation extreme, his broken leg very cold, and the bones entirely ununited. No medicines whatever had been given to protect him against the next chill or paroxysm, which was to approach in 16 or 18 hours, and in which, I was sure he would die, unless it was greatly mitigated or prevented. I forthwith commenced admi- nistering stimulants and tonics, blisters and sinapisms ; and gave be- fore the time of the next chill, 44 grains of quinine, five of opium, and old rum "ad libitum;" and using at the time of the approach of the chill, some other and decided diffusible stimulation, I succeeded in a measure in averting it. I now called in to my aid my friend Dr. B., one of the most skilful and enlightened physicians it is my happiness to know, and we continuing this treatment for several days, our patient recovered without an untoward symptom afterwards. The medicines brought on dark-colored and feculent discharges, the disease gradually disappeared, the bones of his leg re-united, and this gentleman now enjoys fine health. In those cases where the cerebral functions are disturbed, and the disease spends its principal force on the brain and animal functions, the same or a similar treatment, except when meningeal or cerebral inflammation is obvious, is followed by its usual success. The blis- ters, sinapisms, and other applications to the surface, and mercurials, with a more moderate and guarded use of opium, seem to be indi- cated ; and this course, thus modified, I have used with much success. I would not, however, be understood as precluding the use, in differ- ent circumstances, of many other remedies, when they are seemingly indicated. Many of these remedies, to be found in all our treatises on fevers, are useful adjuvants, and were often profitably employed. But not designing to write a labored essay, and only wishing to call attention to the leading remedies, which for many years I have found to succeed so well in our fevers, I will not particularize them. I will, however, here remark, that as long as the disease continued, and un- til the secretions were resumed, I generally gave the opium, Dover's powder and calomel once or oftener in the twenty-four hours. Whenever I could choose the hour of administration, and this was most generally the case, I preferred to give this dose at bed-time, for many and obvious reasons. I thereby derived full benefit from the medicine, and in most cases ensured to the sufferer a night of com- parative comfort and repose, thus robbing the sick chamber of most of its horrors. The patient would generally in the morning be quite refreshed, and the medicines of the preceding night prepare the sys- tem for the free use of the sulphate of quinine, and other tonic reme- dies. MERRITT ON CONGESTIVE FEVER. 73 In regard to the administration of the sulphate of quinine, I was not scrupulous, caring very little as to the mode or the quantity given, so I could bring the system under its fall influence in due season. In most cases, from sixteen to twenty grains would prevent a recurrence of the chill, if the patients had been prepared for their administration by the previous use of the medicines to which I have alluded, and which I have so strongly recommended. I have often given much larger quantities in large doses, and always desire to produce a degree of cinchonism, and have the nervous system well under its influence, some hours before the time of approach for the chill. By pursuing this course, my experience assures me we can nearly always in two or three days, even in the most refractory and unmanageable cases, avert the quotidian and tertian paroxysms, divest them of their dan- ger, and thus secure the lives of our patients. We have been told, that in this class of diseases the sulphate of quinine should be our " first, last, and only remedy." This I consider very unwise advice. It is probably the most important remedy ; but, unaccompanied by other adjuvant agencies, I have seen it fail too often to subscribe to this doctrine. The curative powers of quinine seem to be confined mostly to its action on the nervous system ; and it must be plain to the enlightened physician that we have in our disease other indica- tions to fulfil, and that we cannot safely disregard the secretoiy sys- tem. Indeed, we must view the whole ground before us, and have an eye, in our treatment of this disease, to every system and organ, and guard against all dangers and lesions. I am willing to concede to quinine all- the importance it so justly merits, and in attacking the citadel of disease, assign it the most honorable position on the right wing. But here, to be successful, we must use the whole battery of medicine. We cannot rely on the right wing alone, but must call to our aid the centre and the left wing. To pursue any other course, would be as unwise in us, as it would be in a commander to make an important attack with his right wing alone, and leave his centre and left wing unemployed, to be defeated and destroyed in detail. This practice I have followed with a success highly gratifying to my feelings, and satisfactory to me in all respects, since the autumn of 1825. I then became perfectly aware, from witnessing the great want of success in the treatment of many cases of collapse which I then met with, and which were very common, that much more was necessary than the usual routine practice pursued by physicians, and laid down in our books. I looked closely at the disease, as I encoun- tered it at the bedside, and scanned and analysed the action of all the remedies used — observed the "juvantia and Icedentia" with fear and trembling, and step by step adopted it, and I have to-day more confi- dence in it than I have in any treatment applied to any other disease. It curtails the duration of our fevers fully one-half; it greatly alleviates, and almost takes away the sufferings of our patients. It allays the distressing thirst ; composes the irritability of the stomach, often most distressing, and which, I now disregard, or look upon as a mere chi- mera ; it produces a moisture on the surface, and secretions from all the torpid organs, and it quiets the sufferer's fears. It renders many 74 MERRITT ON CONGESTIVE FEVER. violent cases mild at once, subdues those that are dangerous, and robs them of their danger, and averts disaster and death from those cases in which we see it approaching, if we can judge from comparison with other cases under the usual treatment, and which we daily wit- ness in the medical world. It is a rare thing for the sick not to sleep quietly and refreshingly, and with comfort to themselves, and soon re- cover from their attacks with very little waste of solids, fluids and strength ; and for many years I have had no cases pf typhoid fever in my practice, when I have treated cases in their earlier stages. This is bold ground to assume ; but, sustained by truth, I know it to be im- pregnable, and invite the severest tests at the bedside. When com- pared with other treatment, I fear no defeat there, and will with great pleasure submit it practicalhj to the most critical examination. Desi- rous to discharge faithfully and conscientiously every professional duty, and to use every honest effort to alleviate and lessen human suffering, and having a firm and abiding belief that this practice, when fairly tested, must supersede the present practice laid down in our books, and more or less pursued by the profession, I would be pleased to in- stitute a full and fair comparison of success as tested at the bedside. I perhaps ought to remark, that within the last ten or fifteen years, an analogous practice has been adopted by some of the most skilful sur- geons in the British army and navy with most distinguished success, according to their reports. These, with some of our own Southern physicians, I consider the best authority in our day in the treatment of diseases in southern latitudes, and especially the disease under our consideration. I believe that congestion is generally the result of neglected and badly managed cases of our autumnal fevers. I have very rarely met with this congestive state of fever, without being able to trace it most legitimately and certainly to one or the other of these causes. I have often foretold its advent from an improper dose of medicine. and seen my predictions realized; and so confident am I of the truth of this opinion, that I never fear its approach in cases which are well treated or managed, as I shall in the sequel of these remarks re- commend. I do not believe I have seen one case of decided congestion in a properly managed case of any of our forms of bilious fever for ten years — nor have I witnessed within the same period the common and more dreaded typhoid degeneration of these fevers in such cases. I therefore am forced to conclude that the latter as well as congestion arises from the same causes, and ought never to be met with when physicians have been called to the management of cases in their early stages ; and it is a well-merited reflection on our skill, if they do then occur. Entertaining this view of the nature and causes of " congestion " in our fevers, improperly called " congestive fever ■," and having no doubt that it is based alone on the neglect or maltreatment of our intermit- tent, remittent and continued bilious fever, I will now proceed to make some remarks on the treatment of these forms of our annual autumnal visitant, which I think will nearly always guard and pro- tect our patients from both congestion and the typhoid condition. MERRITT ON CONGESTIVE FEVER. 75 These remarks and this treatment are so closely allied to our subject, and so inseparable from it, that we cannot omit them in this connec- tion, for I consider them as identified, as cause and effect, with it. The causes and pathology of intermittent and remittent fevers are now so well understood, that any remarks from me on these points may be deemed unnecessary, especially as I do not pretend to be able to cast any new light on them. I will also pass by the symptoms of the usual forms of bilious fever, and also their distinctive characters. These are too well known to the profession to need even a more par- ticular passing notice. In all these forms of our fevers I have often seen the most distinct and marked cases of congestion arise under the circumstances to which I have alluded, and against which I am anxious to throw all guards and protection. When called to prescribe for a patient in the cold stage or chill of any of our forms of fever, if it threatens to be obstinate, it has been the practice of some few of my professional friends, as well as my- self, for many years, to give without delay from one to two grains of opium, with ten grains of calomel, or its equivalent of blue mass. If the sufferings of the patient should be severe, and the chilly sensations protracted unreasonably, we have no hesitation at all in repeating the anodyne. It is seldom, however, that a second dose is found neces- sary, for prompt and decided relief is almost certain from the first dose, and that with a success attainable by no other means, however skilfully employed, with which I am acquainted. The chill is most obviously shortened, and the subsequent fever moderated to an extent highly gratifying to the patient, and its duration very much curtailed. When irritability of the stomach exists, I have no knowledge of any therapeutic agent that is calculated so surely to compose it, especially if aided by a sinapism ; and if pain, cramps or looseness of the bowels be present, it seems to be so manifestly indicated, that no one could hesitate in employing it. In short, there are few or no symptoms, except such as point to the graver affections of the brain, which at- tend the cold stage, that would deter me from its use, so great and salutary and controlling have I found its effects in this stage of the disease. I have rarely found it necessary to resort to any other means ; but to most of the remedies usually employed in the cold stage I have no objection as adjuvants. But to rely on them alone, in severe cases, threatening at every step alarming collapse, appears to me the worst species of folly. I have, however, encountered a few cases where I was obliged to administer very freely sulphate of quinine and diffusible alcoholic stimulants, and resort to blisters to ensure the safety of my patients, even in the cold stage. When I have not been called to prescribe, till the cold stage has been passed and the hot supervened, with a view to shorten the hot stage, relieve the febrile s}^mptoms, give ease and comfort, and pre- pare my patient for subsequent treatment and the use of quinine and tonics, I forthwith administer the combination of the anodyne and mercurial, to which I generally add two or three grains of Dover's powder, feeling always well assured the happiest results will follow. The first and speedy effects of this dose are, to bring on a relaxation 76 MERRITT ON CONGESTIVE FEVER. of the skin and remove the thirst, and establish a gentle perspiration or^ the surface, when the fever subsides in about half the time it would have done, if reliance had been placed on the abstraction of blood, cold drinks, and the usual remedies in such cases. We have very high medical authority for the use of opium in the hot stage of fever, and I am decidedly of the opinion its efficacy is greatly en- hanced by this combination. But even supposing, instead of being recommended, it was condemned by the profession generally, I would still cling to it, relying upon my own experience and that of my friends, and sustained, as I think, by the authority of reason and pa- thology, and as I know, by the most flattering success in practice. I am aware that many cases occur in which we may call to our aid many other remedies with advantage. Our treatises on fever abound with recommendations of such remedies, and many of them are under some circumstances quite useful; but as my object is not to write an essay on fevers generally, but to bear my testimony to a particular kind of practice in our autumnal fevers, which I have found very successful, I will not undertake to descant on their virtues, or point out objections to their use. This practice does not at all interfere with the employ- ment of blisters, and in fact many other remedies that may be judged to be proper. But if it is adopted promptly ancbpursued judiciously, there is nothing more certain than that they will be much less fre- quently demanded than in similar cases differently treated. The ne- cessity for bleeding will ver}T rarely exist, active purging will never be required, and the patient will find himself upon recovery possessed of more strength, and in better condition every way, than by any other plan I have ever seen pursued. He will have passed through the period of his confinement, shortened at least one-half, perhaps more ; and instead of having suffered the horrors usually attendant on such cases, he will have spent the time of his disease, if not with comfort, at least with a degree of composure and rest, entirely unknown to those whose misfor- tune it has been to be subjected to the routine of practice usually followed. The thorough evacuation of the bowels by some cathartic medicines, previously to the administration of quinine, I think by no means neces- sary. The use of sulphate of magnesia and other saline purgatives for this purpose, I deem, from much observation, highly injurious, and often imminently hazardous. From long experience, I am quite satisfied that no purgatives, having such high authority for their use, have fewer recommendations, and that they have been productive of more congestions than all the other articles of this class in the materia medica. In most cases there is no need for any such evacuations ; the mercurial itself will generally produce sufficient action from the bowels; but if it should require aid, I would greatly prefer an occa- sional enema, or a dose of castor oil. Before any action from the bowels, our medicine, given either in the cold stage or in the fever, having controlled the activity of the circulation, tranquilized the sys- tem, softened the skin, and brought on a secretory action in the stomach and alimentary canal, we may safely, and with great advan- tage, begin on the sulphate of quinine and other tonics. MERRITT ON CONGESTIVE FEVER. 77 If there be a distinct intermission or remission between the pa- roxysms, it is known to every member of our profession, that this is the most favorable time to administer quinine, the only remedy on which we can safely rely to arrest the disease, and none now hesitate to use it. But should no intermission, or apyrexial state take place, doubts exist in the minds of many physicians as to the propriety of exhibiting it. In urgent cases, I never fail to recommend it. The calomel and opium seem to prepare the patient admirably for its use, and we cannot wait with safety for marked intermissions in many cases. In deciding on the propriety of administering quinine in such cases, I am inclined to believe many are deterred from its use by fears of the existence of internal lesions. I am, however, very far from concurring in the opinion that their existence contra-indicates the free use of this tonic; and when we reflect that every paroxysm adds to the extent, and increases the danger, of congestion, I must conclude that it is far better at once to arrest the chills than to allow them to continue. Indeed, I think we may well doubt whether any amount of visceral lesion necessarily forbids the use of quinine, acting as I suppose it does, chiefly on the nervous system. It is not to be questioned, that under the old plan of treatment, the best time, as a general rule, for giving the quinine is during the inter- mission. Not because the powers of the medicine are greater at one time than another, or that they are impaired during the paroxysm, but on account of the difficulty of giving a patient in that state any kind of medicine, the stomach being generally irritable and unable to bear it. But with the soothing practice we follow, it is very rare to meet with that obstacle to its use, and hence we seldom hesitate to recommend it, if it is at all desirable to administer it at that time. Experience has taught that it can be given at any period ; and to those who have been in the habit of witnessing its operation, it will appear astonishing with what certainty and promptness its febrifuge proper- ties are in most cases manifested. The form in which it is given is a matter of very little importance. In solution it acts rather more promptly than in any other way ; but being extremely bitter and unpleasant to many in solution, I prefer the form of pills. These are also retained more certainly by the sto- mach, and with them I often combine an opiate or mercurial, and, frequently both, as the indications of the case may seem to require*. In most cases 12 or 15 grains in the 24 hours will answer remarks ably well ; but sometimes, in urgent cases, exciting serious apprehen- sions, two or three times that quantity is administered without hesi- tation. In many milder cases, where the paroxysm is short and the symp- toms not distressing, I prefer waiting until bed-time to administer the anodyne-mercurial. By this plan, a night of quietude and re- freshment is ensured to our patients, and they are in the morning in a favorable state for the tonics ; and even in graver and more severe cases, when, with safety, we can wait for a few hours, I much prefer giving this medicine at night. 11 78 MERRITT ON CONGESTIVE FEVER. If any functional derangement or disorder of the chylopoietic vis- cera should remain after the paroxysms of these diseases have been arrested, which requires attention, a few doses of blue mass, and pro- per address to the bowels for a short time, will contribute materially to the permanency of the cure. The remittent and other forms of bilious fever I regard as essentially the same, and requiring to be treated upon the same principles. They are produced by the same causes ; and as they differ only in grade of violence and the duration of paroxysms, it requires only a slight modification of the practice in intermittents to treat successfully the other forms of this disease. The chief indications in the management of bilious fever being to moderate the febrile action in the arterial system, and to obviate gas- trointestinal irritation, and restore the healthy functions of the liver and alimentary tube, I conceive I meet them all by the combination of the opiate and the mercurial recommended in the treatment of in- termittent fever. My practice is to commence with its use, and con- tinue it as long as I may deem it necessary ; and I give it at any period in the progress of the case, if either of the indications enume- rated above still exists. What others aim to effect by the lancet, I think may be accom- plished by an opiate, and more besides. It certainly moderates arterial action to every desirable extent, in most cases ; and in addition to that, it soothes the whole system, relieves pain, allays thirst, tranquilizes the stomach, produces perspiration, and very materially aids the mer- cury in exciting all its desirable effects. It has been objected to the action of opium in this complaint, that it has a tendency to constipate the bowels. But this effect is entirely removed by its combination with calomel ; and in this combination, I consider it the safest, most soothing and certain cathartic I have ever administered. I have often seen it succeed in moving the bowels, and taking away dark discharges, when all other measures had failed. In most cases treated with this mediciue, no other cathartic is ever required ; and when it does need aid, I have generally found an occa- sional enema or a gentle dose of oil amply sufficient to accomplish our wishes. Emetics, cathartics, nitrous powders, and many other remedies, I consider very perturbating and irritating, and their use as irrational and highly injurious. In a disease where there exists such a tendency to gastro-intestinal irritation, as is met with in bilious fever, I cannot conceive what benefit can result from their use ; and it is obvious to my mind from what I have seen, that in most cases they are sadly mischievous. I have never yet found any advantage resulting from the administration of violent and irritating cathartics in this form of fever ; but they seldom fail, according to my observation, to induce a state of irritation in the mucous membranes of the bowels, from which a train of distressing and dangerous consequences arise, in the ad- vanced stages of the disease, which are often more serious and diffi- cult to manage than the original disease. Among the most common consequences of this irrational and imprudent practice, is the produc- tion, in the mucous membranes of the intestinal canal, of a high state MERRITT ON CONGESTIVE FEVER. 79 of irritation, or sub-acute inflammation, causing the disease to lose its original character, and assume a low typhoid form, much more dan- gerous and annoying than the original attack. By this practice I have seen much mischief and disaster produced, and I have no hesi- tation in declaring my solemn conviction that nearly all of our typhoid fevers are thus brought into existence. I am sure I need not, at this late day, enter into a defence of the use of calomel, at least in combination with other medicines, in the treatment of bilious fever. In combination with opium its virtues are greatly increased, and it is at the same time so thoroughly guarded, as to lose all its irritating and unpleasant effects, resulting frequently from its use alone. While I deem the use of calomel or blue mass absolutely necessary in the treatment of bilious fevers, I will here remark, that I always combine it with opium or some other medicine ; and I must here en- ter my protest against the extravagant use of it recommended by some medical authorities of high standing. Instead of 10 or 20 grains every few hours, until the gums are touched, I seldom give more than that quantity in the twenty-four hours. I frequently derive no satis- faction when the specific effects of the medicine are produced, but continue to give it as long as the liver is inactive or engorged. Blisters in this disease are a most important auxiliary in our treat- ment. They are not so often accompanied by strangury or distress as in other cases not treated with the opium. They excite a fine and healthy action on the surface and the internal mucous membranes, and sustain the natural temperature of the skin. In many cases I consider them absolutely essential, and have it in my power to em- ploy them much earlier than is done under other treatment, owing perhaps to opium and calomel preparing the patient for their advan- tageous use. The propriety of employing tonics in this disease is a point I con- sider no longer questionable. Our practice has been to prescribe the quinine promptly and freely, as soon as we discover the liver has re- sumed its regular action ; and if that is tardy in being brought about, and there is any material prostration of the general powers of the system, we combine with it the mercurial preparation, which may be employed to restore the healthy functions of that organ. To the early and free use of quinine is attributable, in my opinion, much of the success attending the practice we recommend in the treatment of our fevers. The patient is prepared, by the early use of opium and calomel, for tonics, which arrest and remove the dis- ease long before serious organic lesions generally ensue. With qui- nine we can nearly always shorten the duration of the attack at once, if there be a distinct remission ; and in cases where there is no ob- vious remission, much benefit results from its use; and we are most generally gratified by the occurrence of remissions, following closely on its exhibition. In cases of great violence, when a paroxysm has occurred, from which the patient has been saved only by the most strenuous exertions, and we have great reason to fear that a similar one will prove fatal, we cannot wai,t> but must have recourse to the 80 MERRITT ON CONGESTIVE FEVER. free and full use of quinine during the remission, however short and imperfect it may be. The quantity given must always be sufficient to bring the system under its influence before the time of the next paroxysm ; and to attain that effect, we must sometimes administer it without stint or measure. [Dr. Merritt read a long and most interesting letter from his friend, Dr. O. A. Browne of Hicks' Ford, Virginia, one of the most enlight- ened and skilful physicians of our country. Dr. B. has long resided in the same district of country with Dr. M., and been engaged in a most extensive and successful practice. He coincides with Dr. M. in his views of the pathology and treatment of our disease, and the other forms of bilious fever also, and most strikingly confirms the great comparative success of this practice, and its vastly superior ad- vantages over the usual routine practice of the present da}\ This letter is replete with sound and philosophical views of the pathology and practice in the diseases under consideration, and much of his letter has been freely incorporated both in substance and in his own language in our abstract. This letter was addressed to Dr. Merritt, and we will conclude with a few more extracts from it : ] "I might, if I had time, give numerous cases which I have wit- nessed, both in my own practice and that of others, that would go very far to establish the superiority of our practice in the treatment of the autumnal diseases of this neighborhood, over that which is still followed by some. But as 1 have not, I must be content with the expression of my opinion, that the superiority does exist in a very marked degree, and that the practice must prevail in all places where it can have a full and fair trial. Having practised long and exten- sively upon both plans, I have had ample opportunities, from my own experience, of making the comparison ; and the conclusion at which I have arrived, is sanctioned by all of my friends who have adopted it, not one having abandoned it, who has given it a sufficient trial. "Under the old practice, I think myself within bounds when I say, that not less than eight or ten days are usually necessaiy to cure a case of bilious fever. You, I am sure, will be willing to verify my assertion, that it is by no means common for us to have a case on hand more than half of that time. That fact of itself ought to be sufficient to cause the preference to be given to the new plan. But it has the additional recommendation of greater certainty of cure, as I think can be esta- blished by the testimony of all who, like myself, have the opportunity of witnessing the operation of both systems. " Besides the advantages already pointed out, there are others of much importance that ought to claim the consideration of every phy- sician. In the first place, it eminently commends itself by its simplicity. By it the patient usually escapes much of the pain and suffering which usually attend such cases when differently treated, and is often con- ducted through all the stages of the disease, with a degree of comfort which deprives the sick bed of most of its horrors. He is for the most part relieved from pai?i, has often refreshing sleep, and when he gets up finds himself possessed of a degree of strength tlwt it is impossible he could have retained under the evacuating treatment commonly pursued. METTAUER ON SCARLET FEVER. 81 "Not the least of its advantages is, that by it the patient is almost completely insured against congestion, when the practice is adopted early, and judiciously carried out. You and I both recollect, when conges- tive fever was common in this region, and thai a patient was con- sidered as having his death warrant signed when it was announced that he had it. Now, we know, it is of very unfrequent occurrence, and that it is extremely rare to see a case at all. All that I have seen for several years past, were the result of improper practice in inter- mittent and remittent fevers, or of the grossest neglect." I might add some other advantages, if it were at all necessary, of this practice, and among them the comparative freedom from anxiety and mental disquietude on the part of the physician himself, and the very rare circumstance of his being disturbed by calls at night. But I hope the above enumerated catalogue will be enough to call the attention of the profession to it, and induce them to give it a full and fair and impartial trial. It is all its friends claim for it, entertaining no doubt of its final success and adoption by those who will give it an impartial test; and with these observations it is commended to the candid consideration of the profession. If it realizes the expectations of its advocates, and the superior advantages so fearlessly set forth in its behalf, it will prove one of the greatest boons in modern times to suffering humanity, and relieve us from an opprobrium, too often cast upon us, that practical medicine has made but little improvement since the days of Sydenham. For the Stethoscope. Practical Observations on Scarlet Fever. By John P. Mettauer, M. D., L. L. D., Professor of the Principles and Practice of Medicine and Surgery in the Medical Department of Randolph Macon College of Virginia, January 11th, 1851. The characteristic symptoms of scarlatina are generally so well known to practitioners of ri iedicine, that it will be needless to repeat them in a paper like the present, designed to be practical. Three principal varieties of the disease are generally admitted by the profession ; that is, scarlatina simplex, scarlatina a.nginosa, and scarlatina maligna. It belongs to the major exanthemata, is inflammatory in its commence- ment, but rapidly tends, like typhoid fever and erysipelas, to depres- sion ; and is chiefly a disease of childhood. Scarlatina simplex is generally distinguished by the mildness of the attending symptoms, more especially by the mildness of the affection of the throat, if that symptom should attend at all. The fever and rash are the chief symptoms of this variety to which attention is usu- ally directed, but in a good many instances the fauces are also more or less reddened or inflamed, and sore in some cases, but seldom to a se- rious extent. Scarlatina anginosa is characterized chiefly by the violence of the 82 METTAUER ON SCARLET FEVER. throat affection, though it too is attended with a rash. The earhr commencement of this variety is generally attended with stiffness of the jaws, soreness of the throat, and more or less pain and difficulty in swallowing. The eruption does not appear as early as in the sim- ple form, being delayed to the third or fourth, instead of the second day, at which time it usually appears in the simple variety. The rash too is less abundant and diffused in this form, and may even be con- fined to a particular part, as the hand or arm, or distributed in distinct spots, very sparsely diffused over the trunk, separated by the inter- vening skin of its natural color. In some instances, however, it makes its appearance generally over the whole surface, displaying the uni- form and scarlet redness of the simple variety. Now and then, after partially appearing, the eruption recedes and returns after a longer or shorter interval: and these alternations may be repeated several times. The fever of this variety is generally more intense than in the simple, and is often attended with delirium or coma. The pulse is usually greatly accelerated beyond its normal condition, and the skin is ex- ceedingly hot. The inflammation and swelling of the throat are some- times frightfully intense, not only causing great pain, but actually im- peding deglutition and respiration. Scarlatina Maligna. — It is not unusual in this variety for complete prostration to mark the commencement of the attack, and even for death to take place at once, without the slightest reaction. In these examples sudden and extensive disorganization of the cerebral func- tions may be induced by the cause of the disease operating upon a constitution naturally unsound, or rendered so by bad habits. Cases sometimes are to be met with, when scarlet fever prevails extensively, in which comatose symptoms, faintness, anxiety, a feeble, small, fre- quent and irregular pulse ; cool or hot skin unequally manifested ; slow, impeded respiration, or irregular and accelerated ; pale or livid face ; great muscular debility, and now and then complete coma occur. In such examples there will be feeble efforts at reaction, and the febrile heat, if developed, will be transitory and partial ; or if the rash appear, it will assume a violet hue, and only shew itself in spots or small patches, and generally the powers of the system seem to give way, and death closes the scene on the third day from the attack. Sometimes reaction comes on, and a low fever follows, at- tended with delirium, stupor, a feeble pulse, a livid, purplish or dark red eruption ; petechia? ; haemorrhage ; involuntary discharges from the bowels and bladder, and frequently death takes place in a few days. But when the cause operates less violently, and the constitu- tion is more vigorous, the attack comes on with symptoms of the anginose variety. The affection of the throat is distinguished by a deeper redness, inclining to purple, and the symptoms are decidedly typhoidal or malignant as the disease advances, distinguished by in- creasing feebleness of pulse, unequal warmth of the body, a fading and re-appearing rash of a livid or purplish hue, &c. These symp- toms, although menacing in the highest degree, are not always the harbingers of a fatal result. It is by no means uncommon for reco- veries to take place in this form of the disease, after the case has as- METTAUER ON SCARLET FEVER. 83 sumed the most fearfully unpromising conditions, both of the local and general affections. Anomalous scarlatina is occasionally to be met with during the prevalence of the ordinary varieties of the disease, and sometimes, too, it occurs as the prevailing form, but is liable to appear endemi- cally, and is often confined to a particular family. It is the disease without the rash, and its seat is the fauces, attended with more or less general fever, however. This variety pursues the course of ordi- nary scarlatina as respects the throat affection, and is distinguished by symptoms of every grade of intensity. Scarlatina is unquestionably an inflammatory disease, and the skin, as well as the mucous and serous surfaces, seem to be its principal seats. Professor C. D. Meigs considers it to be an inflammatory af- fection, and refers its seat to the membrana vase/rum communis, or the endangium of Mr. Burdah. He bestows the epithet of ' en&angitis upon the inflammation, and ingeniously argues in support of his theory. The opinion of Professor Meigs on this subject, or any other connected with medicine, is entitled to the highest respect. Scarlet fever, in some respects, is assimilated to typhoid fever, in nature, both being inflammatory, but the inflammation consisting of mixed characters ; and these two diseases are to be met with of nearly every grade of mixed inflammatory irritation, and their tendency is to early depres- sion of the energies, and to assume adynamic characters. In scarla- tina the inflammation passes rapidly through its acute stage, and by reason of its rapid tendency to depression, if an active treatment of enfeebling nature is to be employed, it must be adopted in the very commencement of the early stage. In many cases of scarlatina, as well as of typhoid fever, our most successful mode of treating them is by the early and decisive employment of the lancet and other en- feebling remedies. We, by such treatment, superinduce direct de- bility, and substitute it for indirect, or what I term ataxic debility, and thus disarm these diseases of their most menacing and dangerous ten- tencies. As a general thing, scarlet fever occurs but once with the same person, though it must be conceded that many departures from this course have occurred. It has seemed to me that second attacks have chiefly taken place with individuals who were affected with the disease partially : that is, who either had the rash without the af- fection of the throat, or the throat affection without the rash, in both cases indicating that the disease was imperfectly formed. Treatment. — In the mild form, scarlatina, in a vast number of in- stances, requires very little, if any, medical treatment. There is always fever, and in the onset of the disease it is generally intense, and attended with more or less disturbance of the secretory exercises. To maintain these balanced, as far as is consistent with a diseased state of the system, with the earliest appearance of the rash, I have found an emetic, consisting of calomel and ipecacuanha, to meet the indications most perfectly, especially if the tongue is coated. Five or ten grains of ipecacuanha, and three or five of calomel, if the subject be a child, or larger doses if an adult, I have employed in hundreds 84 METTAUER ON SCARLET FEVER. of cases of the simple and mild form of the disease, with signal benefit. Subsequent to the operation of the emetic, if the calomel fails to purge, or acts imperfectly, a moderate portion of oil should be given, taking care, however, to allow some three or four hours to intervene between the termination of the emetic commotion and the administration of the cathartic. After the bowels have been opened, it will only be neces- sary to maintain their solubility by the gentlest means. To this end I have employed indiscriminately, a solution of the bitartrate of potash and sulphate of magnesia, and the acetate of potash, administered two or three times during the 24 hours, and just in doses to act moderately upon the bowels. A mixture formed of 3 ij. of the sulph. magnesia, 3 j. of bitart. potass., and 1 ij. of water, administered in tablespoon- ful doses, will be found both grateful and beneficial in these cases with children. With adults, of course, larger doses will be required. Be- sides the cathartic action, it also produces febrifuge, or rather refrige- rent effects. The acetate of potash operates very nearly in like man- ner ; and when the crystalized article is employed, which should be preferred, from two to five grains in watery solution may be adminis- tered at a dose. It is all-important that the temperature should be rendered as agreeable as possible. If the heat is excessive, exposing the surface of the body to the air, or sponging it with water and vine- gar until it moderates, will afford relief to the patient's sufferings, as well as ameliorate that most distressing symptom. The patient must be allowed to use cold or cool drinks, and cool slippery elm tea will generally answer best.. A restricted diet is all-important ; everything exciting must be carefully inhibited. Confinement in bed will be ne- cessary, even in the mildest cases, until complete desquamation has taken place. Should the throat be much affected, as will sometimes be the case, it will be proper to apply gargles or other topical reme- dies to it. As a gargle, nothing answers better than a strong solution of the borate of soda. Sage tea, with the nitrate of potash ; solutions of the sulphate of magnesia, or soda ; the chloride of soda ; vinegar and water; dulcified spirits of nitre and water, and the nitrate of sil- ver, either in strong solution, or the solid nitrate may also be used as topical remedies. Generally, however, they will not be required, by reason of the mildness of the anginose affection. Bleeding, when the simple variety puts on more violent characters, and the febrile symptoms run high, especially if the patient's constitu- tion is very good, will be proper and allowable in many cases. With -children from five to eight or ten years of age, bleeding would prove highly beneficial, particularly if there should be strong cephalic ten- dencies. Even with younger subjects, blood-letting might be employed with safety and advantage. With these it would be safest to abstract the blood by leeching, and the temples or other convenient parts near the head should be selected for the operation. The bleeding, no mat- ter how effected, must be used in the very onset of the fever, and to the extent of impressing the action of the heart and arteries decidedly. One decisive bleeding will be far more beneficial and safe in the early beginning of the disease, than a repetition of it after the fever has somewhat advanced. Frequently it will reduce the fever at once to METTAUER ON SCARLET FEVER. 85 the proper degree for bringing out, and for sustaining the rash in its ordinary development and self-limiting tendencies. The direct de- bility it induces weakens but does not exhaust the vital energies, and guards the constitution in a great degree from indirect, or as I have denominated it, ataxic debility, which is always dangerous, and far more difficult to correct than pure debility. If one bleeding does not control the pulse, a second, or even a third repetition must be em- ployed. Refrigerants will, in some cases, be found of great benefit in this variety also, used after bleeding. Now and then their employment will supersede the necessity of using the lancet, particularly in those cases characterized by great exaltation of the animal temperature. In such examples the fever is kept up or aggravated by the undue temperature; and when reduced by refrigerating, both through the skin and stomach, both the violence of the fever and the patient's sufferings are mitigated at the same time. In the employment of this valuable and grateful remedy, it will be proper that its depressing agency shall not be urged to the extent of interfering with the eruptive tendencies. Gently sponging the heated regions of the body, from time to time, and allowing cold drinks or pounded ice, merely to moderate the un- due animal temperature, will enable us to meet the indication with certainty and without danger. Cathartics will generally be required in this variety. In some cases they may even supersede the use of the lancet or refrigerants. Early in the disease it will be proper to purge decisively ; and the cathartic I have generally preferred and employed, is the mercurio-saline ; that is, to administer the requisite dose of calomel with a minute portion of ipecacuanha, and to follow it up in four, six or eight hours with a dose of sulphate of magnesia, acidulated with the bi tartrate of pot- ash. In some cases, I have employed the infusion of senna with be- nefit when the bowels were torpid. I have also, at different times, had recourse to oil and the syrup of rhubarb. The last named article is particularly suited to the cases attended with diarrhoea. Purging must invariably act impressively ; and if the first dose fails to procure consistent as well as copious evacuations, the cathartic should be re- peated in six or eight hours. Diaphoretics will be demanded early after sufficient purging has been premised ; and for children nothing answers better, according to our experience, than minute doses of ipecacuanha and the nitrate* or bicarbonate of potash, administered in watery mixture, or in the form of powder or pill. From the third to half a grain of ipecacu- anha, and one, two or three of the nitrate or bicarbonate of potash may be administered at a dose once in three or four hours, and will often be followed, after a few doses, by relaxation of the skin and diaphoresis. This diaphoretic is particularly suited to children in catarrhal affections, more especially in the bronchitic forms. Certain aromatic teas may also be employed beneficially as diaphoretics, after the force of the pulse is greatly subdued, and when there is a ten- dency to recession of the animal temperature from the surface ; such as the teas of balm, sage, elder flowers, saffron, boneset, dittany, &c. 12 86 METTAUER ON SCARLET FEVER. Employed moderately warm, the exciting qualities of these ptisans render them active and decidedly diaphoretic in many instances. In some cases the warm teas of slippery elm, flaxseed and althea will be found of great benefit, both as diaphoretics and demulcent diure- tics, when the urinary secretion is greatly defective, or when the se- cretions generally possess undue acrimony. Revellents will be required in some cases when the disease introverts upon the internal organs. Should the lungs, pleura, stomach, intes- tines, bladder, uterus or brain be seriously menaced, after venesection and other enfeebling remedies had been employed, it would be proper to have recourse at once to these valuable measures. In most cases involving the pectoral organs, revulsion, by dry cupping or sinapisms, is to be preferred as the first trial of the agency. If, however, the symptoms are very acute, and the pulse active and strong, humid cupping must be employed. The pectoral spine should always be counter-irritated also in these cases, as an important influence is of- ten exerted upon thoracic diseases through it if effectually performed. If the local affection is connected with an enfeebled constitution, or if a state of debilit}^ exist, resulting chiefly from the duration of the primary affection, it would be best to use vesicants. The propriety of employing revellents to the throat, in the anginose affection, has been questioned. Vesicants, as a general rule, should not be em- ployed, as they greatly augment the patient's suffering, and frequently irritate the faucial affection. Rubefaciants that act moderate^ should be preferred, such as the ammoniated, camphorated, and terebinthi- nated liniments. In most cases, the oil of turpentine with sweet oil will answer best, mixed in nearly equal proportions. These reme- dies applied four or five times during the 24 hours, less or more fre- quently, will excite and keep up the proper counter-irritation in the skin, without incommoding the patient or aggravating the anginose affection. As topical remedies, the gargles and other applications already sug- gested will be of service, and must be employed. In this variety, if there is intense heat of the fauces, it would be advisable to use cold water gargles, or pounded ice to the throat, governed by the cautions laid down in reference to the employment of refrigerants generally. Should sloughs form in the throat the parts must be touched occa- sionally with spirits of turpentine, or the ammoniaret of copper in solution, prepared by dissolving sulphate of copper in diluted water of ammonia. These applications are far better than the nitrate of silver; they promptly change the disorganizing action into granulating and reparative. The ammoniaret of copper is best suited to those cases of some continuance, but I have often used it beneficially in the com- mencement of the sloughing process : it is to be applied with a soft mop previously saturated with the solution, simply pressed on the slough once daily. Very soon the slough will be cast off", exposing a healthy looking granulating surface, which of course is to be managed as a common healthy ulcer. The drinks and nourishment to be as suggested in the simple form. Great care will be required during desquamation, and for some time METTAUER ON SCARLET FEVER. 87 after, in regulating the bowels, diet and exercise. Early exposure to wet, cool, or. variable atmosphere must be inhibited, even after con- valescence has considerably advanced. In the anginose variety, the general treatment suggested in the simple will be applicable. Early and decisive bleeding will be re- quired in a majority of instances, both generally and locally employed. If the anginose affection is violent, it would not be safe to rely on general bleeding, but the region of the affected part must be leeched freely. In some very threatening cases I have resorted to scarifica- tions, and have never regretted their employment. The free discharge of blood they cause, speedily reduces the swelling and heat of the fauces, and the incisions take an ordinary traumatic inflammation, which tends to change the original disorganizing inflammation into one of a more favorable description. Early after bleeding it will be proper to employ emetics, and the compound already suggested will meet the indication fully, if its strength is somewhat augmented. In most cases the emetic should be repeated every tenth or twelfth hour, until the anginose symptoms ameliorate. A single dose will frequently arrest the anginose affec- tion, and impart to the constitutional symptoms an improved con- dition likewise. More frequently, however, it will be necessary to employ several emetics before a favorable impression is made on the disease. Cathartics will be demanded early in the treatment, and if the ca- lomel, administered with the emetic dose, fails to purge in four or five hours after it is taken, a dose of oil, or salts and magnesia, should be given. The aromatic infusion of" senna and salts" is also admirably suited to this variety as a cathartic ; and when the bowels are in a diarrhceal condition, rhubarb in substance, in combination with blue mass, and a small portion of ipecacuanha, will be found to meet the indications fully. It is not proper to purge actively y but the secre- tories should be ameliorated, and for this end those agents that im- press the mucous membrane of the enteritic cavity, decidedly, but moderately, should be preferred. Such agents procure copious and consistent evacuations ; and the articles already mentioned will be found generally to act in that manner. A soluble state of the bowels should be maintained throughout the whole course of the disease, and for this purpose nothing succeeds better than the simple syrup of rhubarb, administered once or twice daily, in moderate doses. Refrigerants can be safely and beneficially used, but only when the animal temperature is unduly exalted ; and the modes already sug- gested, as well as the rules for their employment, are equally appli- cable in this variety. In the early stage there will be little danger in the employment of refrigeration, as the energies are not likely to be suddenly or unduly depressed by its operation. In the advanced periods, however, sudden depression might follow, if the remedy should be too profoundly or improperly used, and dangerous con- sequences result. Very light sponging of the surface with vinegar and water, or spirit and water, with cool drinks or pounded ice, merely to moderate the undue animal temperature, but not to depress it suddenly, is all that should be attempted. 88 METTAUER ON SCARLET FEVER. Diaphoretics will be demanded as soon as the force of the pulse has been subdued, and the means already suggested may be employed. The ipecacuanha and nitrate or bicarbonate of potash will be found an admirable diaphoretic in this variety, and should be preferred, according to my experience, to all other agents of this class, in the earlier periods of the disease. After it is commenced, the remedy should be continuously employed until its proper effects are produced. In the subacute stage stimulating sudorifics will often be required ; and a combination of gum camphor with the ipecacuanha, in suitable doses, or the spiritus mindereri, or the dulcified spirit nitre alone, or united with ipecacuanha, or tartar emetic, or warm stimulating teas, such as I have already pointed out, may be employed. In some cases Dover's powder might be beneficially resorted to with adults, when there is great restlessness at night ; but with children it can be seldom used with safety. Revellents will sometimes be demanded to combat certain coincident local affections, as was remarked of the treatment of the more intense forms of the simple variety. In these affections the suggestions already made must suffice. When the animal temperature, however, is unequally diffused, it will be necessary to employ revellents, with the design of restoring it to those regions in which it is defective, as well as to equalize the circulation of the blood. With these intentions friction, rubefaction by mustard seed, heat artifically applied, ammo- nia, capsicum, spirit of turpentine and vericants may be employed as they seem indicated. The topical treatment of this variety differs little from that considered in the preceding. It will be proper to emplo}r the same remedies, but in many cases they must be used more energetically. As soon as a slaugh forms in the fauces it must be separated by the decisive use of the solution of the ammoniaret of copper, applied as already advised ; and after it is cast off, it will only be necessary to use mild gargles formed of gentle astringents and demulcents. Should the slough re- appear, or the ulcer, left by the one cast off, assume unhealthy appear- ances, the ammoniaret must be again applied, or some other of the local contra-irritants already pointed out as useful in such cases, ac- cording to the condition of the ulcer. Stimulants and tonics will be demanded in the depressing stage, should there be marked debility, and a tendency to dangerous in- crease of it — a condition frequently to be met with when the case is protracted and the anginose affection violent. As stimulants, nothing answers better than mint julep or milk toddy, administered in quan- tities and formed of a strength to suit the particular case and the age of the patient. The object should be merely to re-excite and main- tain the action moderately exalted whenever collapse threatens. Tonics will be demanded, if stimulants fail to maintain the action induced by them sustaining and equable ; and as far as my expe- rience enables me to decide, the infusions of chamomile flowers and wild cherry bark are to be preferred with children. These infusions may be converted into syrup by the addition of sugar, which form renders them less offensive to children, and of course more easilv METTAUER ON SCARLET FEVER. 89 taken. Even with adults they may be used beneficially, though with them the infusion of bark, columbo and gentian answer best. Tonics, however, are hazardous remedies in this disease, and should not be employed hastily or rashly. In the dropsy of this variety, as well as that of simple and malig- nant scarlatina, a combination of tonics, cathartics and diuretics has generally succeeded best in my hands; and the form I employ is that contained by the annexed formula : PL Fol. Senn. 3 iss. Flor. Anthene. Nob. 3 ss. Fol. Digital. Dup. 3 iss. Sem. Anis. 3 j. Sulph. Magnes. lj. Aq. Bullient. 1 xij. Infuse in a close vessel for half an hour, then strain. Dose from £3 ij. to f>1 j. twice or three times daily. A tablespoonful, more or less, according to the age or strength of the patient, administered three or four times during the day, so as to act moderately on the bowels and kidneys, will very speedily remove the dropsical affection. In a vast number of cases I have employed this remedy, and have never been disappointed in its effects. If it purges too freely at first, no injury will result ; and after the remedy is employed a while, it will only act moderately, rather as an ape- rient : its diuretic operation is generally decided. The infusion must be continued for a week after the subsidence of all tumefaction ; and the bowels after it to be kept soluble. In the malignant variety it will seldom be safe to bleed, by reason of the rapid tendency of the disease to depression, unless the case com- mence as scarlatina simplex or scarlatina anginosa. Our chief reli- ance must be on emetics, cathartics, refrigerants, diaphoretics, stimu- lants, tonics, revellents and contra-irritants. In the commencement of the attack it will in every case be proper to vomit freely ; and the emetic already suggested in the anginosa variety, will be found to meet the indications. In some cases it might be proper to augment the dose, or the emetic would not act by reason of the insensible state of the stomach. The turpeth mineral was suggested by the late Profes- sor Benjamin Smith Barton of the University of Pennsylvania as an emetic in this variety of the disease when there was gastric insensi- bility ; and within the last twenty years the same article was vaunted through Virginia as a specific though secret remedy in every variety of scarlatina ; and in an advertisement through the newspapers, a Vir- ginia physician and a graduate referred the suffering public to a dis- tinguished apothecary in Philadelphia for a supply of his secret re- medy— a complete humbug. The vomiting should be effective, or little benefit will follow from it ; and it ma}r be repeated several times af- ter intervals of eight or ten hours. Cathartics will be demanded early in the disease ; and if the calo- mel of the emetic compound should not purge in four or five hours, it will be proper to administer a suitable dose of oil, the bitter aromatic 90 ASYLUMS FOR THE INSANE. infusion of senna, or a commanding dose of the syrup or powder of rhubarb, with one or two grains of aloes. In all respects purging in this variety must be governed by the same indications, and directed to the same objects requiring them in the preceding. The same may be remarked of refrigerants, diaphoretics, stimulants, tonics, revellents and contra-irritants. The toxical treatment will be the same as was advised in the angi- nose variety, only that it must be more energetically employed. It will be important from time to time to remove the obstructing mucous from the nostrils, to allow patients to breathe through those passages, and not through the mouth. This may be done by carefully absorb- ing it with elongated pieces of soft sponge, or small rolls of bibulous cloth introduced carefully into the nostrils from time to time. The fauces, too, must be cleansed of their tenacious and adhering mucus, by gently wiping it away with a soft mop formed of old linen or sponge. The onion poultice I have often used to the exterior of the throat with much benefit. Blisters should seldom if ever be drawn over the ex- terior of the throat, or indeed elsewhere, in this variety, as they are prone to take on disorganizing inflammation. The room must be ren- dered comfortable, both as to temperature and ventilation. A heated room, with a highly rarefied state of the atmosphere, would certainly increase the patient's restlessness, as well as the unpromising charac- ters of the disease, by withholding from the lungs the proper supply of oxygen, so necessary in a disease constantly tending to disorganize the vital energies that are chiefly maintained by its vitalizing influ- ences. During the convalescing stage it will be proper to guard carefully against exposure and excesses of every kind. The bowels must be carefully attended to. Constipation should not be allowed to take place. In most cases of this variety of the disease, recoveries take place slowly, and on that account the utmost attention should be given to the convalescing stage. Generally the body should be protected against the atmospheric transitions of temperature by the use of flannel. Inunction in scarlet fever, as practised by Dr. Schneemann of Hano- ver, I have never employed ; but from the report of Dr. S. and Dr. Harvey Lindsly of Washington city, I am disposed to think favora- bly of it, and hope it will be fairly tried in the United States. It may do good, but cannot do hurt. On Asylums for the Insane. Asylums for the insane are charities, which, like other establish- ments for somewhat analogous purposes, are the concomitants or effects of the increasing civilization characterizing the last three cen- turies. It is true that the earliest may be traced to a date far into the past ; but, like the primordial attempts at inventions, which often long precede success, these few institutions for the purpose were but slight evidence of a tendency in that direction. The original idea upon which such institutions are based, apart from charitable motives, is the ASYLUMS FOR THE INSANE. 91 circumstance, that the necessity to protect the public from the fury of the maniac makes his confinement in many instances absolutely re- quisite. But again, taking this idea in another sense, one more appro- priate to the philanthropic considerations of the present day, it is found that, so far as the insane person himself is concerned, in general his own safety is better guarded than it could be elsewhere. It is true that in asylums occasional examples of suicide and other sad occurrences are almost necessary facts. But this does not contravene the general rule — it does but confirm it. For, on looking over the yearly file of almost any newspaper, the number of suicides palpably due to insane impulse, of which we may there read an account, is out of all propor- tion to similar statistics of any institution for the mentally afflicted. But again, what has led to the establishment of lunatic asylums to so large an extent in modern times, is, in the first place, that far more patients are here cured than is the case with equal numbers treated in private ; and secondly, to the great mass of those bereft of a sound mind, such abodes, although attended by separation from relatives and home, yet prove far more conducive to their comfort and happiness, than would enure to them if this severance did not take place. It is these last two considerations that make it the imperative duty of all countries fitly to provide for their insane. And especially does this idea apply to the pauper insane ; for, could we conceive a more ca- lamitous condition for an individual, than to be in circumstances re- quiring the most earnest daily exertion to " make both ends meet," whilst a near and dear relative may require rigorous restraint at home for the want of friends to watch him. We rejoice that the common- wealth of Virginia has come up to her duty in this respect; under the present noble laws as to the particular here considered, no inhabitant of her extensive confines, whether bond or free, whether white or black, whether rich or poor, is refused the aid which an asylum can bestow. In comparing the situation of the insane without and within an asylum, we have on the one hand, in the first place, the most care- fully devised means for the moral and medical treatment of insanity, whilst on the other, there is either a total want of these, or they are applied inefficiently and partially. And secondly, in the one situation, the comfort of the patient is better attended to, and he is subject to a less strict management than in the other. All the important hygienic regulations as to ventilation, modes of heating, suitable food and clothing, and attention generally to what were entitled by the ancient physicians res non nalurales, now obtain from every superintendent of a lunatic asylum the greatest and most zealous study. Measures savouring of coercion are also reduced as far as possible to a mini- mum ; and the use of chains and such like means are wholly relin- quished, whilst they are still but too often employed in private. We have before us a number of works on insanity, in which the subject discussed above is referred to, and the same remark holds good as to an extensive collection of the reports of institutions for the insane. There are also reports from committees in various states of the Union, appointed to search out the condition of the insane amongst the population at large in those communities ; and moreover, 92 ASYLUMS FOR THE INSANE. Miss Dix, the eminent philanthropist, has published a number of pamphlets, detailing her experience throughout a large portion of the Union. By these productions this excellent lady has caused asylums to be erected where little interest in that regard had previously existed, and has also given increased impetus to exertions towards the same end, where this noble cause had been sustained by other individuals. In her memorial to congress, presented on the 27th of June, 1848, she arrives at the general conclusion, that the wretched condition of a multitude of the insane not placed in asylums does not differ in the several members of the American confederacy ; and of nearly ten thousand idiots, epileptics and insane persons whom she had sought out and seen, there have, she says, been hundreds, nay, rather thousands, bound with galling chains, bowed beneath fetters and heavy iron balls, attached to drag-chains, lacerated with ropes, scourged with rods and terrified beneath storms of profane execrations and cruel blows. It would be false policy to blame too much those having charge of these unfortunates for a state of things so lament- able ; it seems almost inherent in the want of proper means which usually attends the management of the insane in private. And we thus perceive also, from the statement of Miss Dix, that there is little difference in one section of America from another. It may be re- marked, however, that she thus alludes to our commonwealth : " The laws of Virginia forbid a protracted detention of the insane in the county prisons at this period. Formerly, I have traced the most cruel sufferings in the confined apartments, uncleansed and unventi- lated, and the still more neglected dungeons into which the insane have been cast." The desirable change here referred to was brought about, first, by representations and statements made in the report of the Eastern asylum for the }Tear 1843, and, secondly, by the wise liberality of the legislature in making suitable provisions for the insane in Virginia. The congressional document of Miss Dix just men- tioned contains pretty much a complete resume of her charitable labors in the various states of the Union which she had traversed, up to 1848, on the same estimable errand. It may not be uninteresting to those having the welfare of the insane at heart, to detail the remarks of other enquirers pursuing analogous researches. Dr. de Vitre, formerly physician to the Lancaster county asylum in England, and at present one of the commissioners in lunacy of that county, gives a number of striking facts in an able pamphlet on the subject under consideration. Amongst other instances, he relates that of a poor man whose wife became insane. He at first tried to do the best he could for her at home. But as her case progressed, fresh difficulties beset him on every side, and when all his little earnings were ex- hausted and he could no longer remain at home in charge of his wife, being compelled to labor for his daily bread, he adopted the extraor- dinary expedient of enclosing her in a large packing case, with a small aperture cut in the lid, through which she could breathe and see, but not large enough to permit her head to pass through. Thus did this poor creature remain a long time, literally screwed up in a wooden case, and was only at last liberated by the humane inter- ASYLUMS FOR THE INSANE. 93 position of two medical gentlemen, through whose instrumentality she was removed to a public asylum, and whose disinterestedness was rewarded by the ultimate recovery of their patient. Another child of misfortune, a male sufferer, was usually chained or confined in a railed-off corner of a barn or other out-house, without clothing of any description, and his only bed consisted of a little straw. In the same locality, says he, there was a lunatic of limited income, residing with his own brother, who ;has been chained for years in a cellar on a bed of straw, who is never allowed to leave his dungeon, and who has not been shaven for upwards of seven years. A third example was an insane son. At first he was chained by his father ; but by and bye a communication was made from the house into a hay -loft, all access with the stable below being first cut off, and into this loft the maniac was thrust. He had no clothes given him, no light to cheer him, no stream of air to refresh him, no water to wash himself with, and only a little straw for a bed. Previously to the erection of the hospital at Worcester, Massachusetts, the commissioners appointed for that purpose reported a case in which the patient had been twenty-eight years in prison ; for seven years he had not felt the influence of fire, and many nights he had not lain down for fear of freezing. He had not been shaved for twenty-eight years. Another individual in the same stale is mentioned, of seventy years of age, who had been chained for twenty-five years, and had his chain taken off but once in that time. From investigations made by a committee of the legislature of Connecticut, they report that there were probably more than seventy lunatics in the state in close confinement by chains and cells. A similar committee some years since made a detailed re- port to the legislature of Pennsylvania. In one of the counties they re- ceived information that the accommodation for the insane in the poor- house consisted of a single room, in which the furious and violent were confined, males and females, in the same department, separated only by the length and restraint of their chains. In another county the apartments were damp, confined, ill ventilated, and several lives had been actually lost from the improper construction of the cells for the insane. When permitted to take exercise and recreation in the open air, these unfortunates were loaded with hobbles and chains, and exposed in summer to the hot sun, without the shade of a single shady tree. In another prison, two lunatics, a man and woman, each over seventy years of age, occupied the same apartment of an upper story. The female was lying upon a heap of straw under a broken window, through which a severe snow-storm was beating upon her. The man had been in that room twenty-one years. A woman was found in the cellar of a prison, in an apartment six feet by eight, and the only place for admission of air by day or night, was six inches by four ; and here she had lived seventeen years, or more than half a generation. In a poor-house in Delaware, a visitor reports that there were twenty insane persons ; each of them in a dark, illy-ventilated room, and each chained to a ring in the centre of the apartment. But it is needless to multiply further these painful accounts. Doubtless every state in the Union, unprovided with asylums, would furnish 13 #•*• 94 ASYLUMS FOR THE INSANE. scenes but too exactly corresponding with the above, and also of but too frequent occurrence. After such details as the above have been substantiated, as they must ever be by suitable enquiries, the duty of the citizens of all civi- lized communities is direct and unmistakeable. If this great amount of misery is to be alleviated or removed, it can only be through the intervention of asylums properly constructed and governed. And if in the establishment of these asylums we would recede as far as pos- sible from the management of poor-houses and prisons, the main fea- tures of improvement will consist in appropriate architectural arrange- ments and a judicious organization. In connection with the former topic we would speak but as to a single point, and that is, the build- ings for the insane should be fire-proof. If this precaution should be adopted in an edifice of any kind whatever, it would seem demanded in a lunatic asylum. For it must be ever remembered that we have here a number of patients locked up, thus differing from ordinary in- dividuals ; secondly, the windows of these institutions are so guarded as to prevent all escape through them ; and thirdly, the character of insanity is often such as entirely to prevent co-operative efforts on the part of the poor lunatic, or indeed may even induce him to resist efforts made for his safety. Hence it is that Dr. Conolly well remarks, in his valuable treatise on the "Construction and Government of Lu- natic Asylums :" " The savings to be effected by omitting the simple precaution of having all parts of the building fire-proof, is not to be put in competition with this horrible danger." We are glad to observe that in a magnificent structure lately erected near London, and capable of containing a thousand lunatics, one of the provisions is, that the whole establishment is completely fire-proof. Respecting the organization of an asylum, it appears worthy of re- mark, in the first place, that an increased number of those officials or attendants in the constant and direct management of the inmates, and watching over them night and day, is still needed in all asylums. The insane are left too much under the general management of the establishment, whilst various particular cases may require, for their most successful treatment, the exclusive action of one sane mind for days and weeks uninterruptedly. Sometimes also a patient is closely confined, who is inclined to violence, or suicide, or elopement, because there is not an attendant to devote himself exclusively to the preven- tion of these occurrences. Secondly, in arranging the organization of an asylum, due caution should be used, lest this power should be en- trusted to any but those capable of suggesting a suitable plan, from their knowledge and experience concerning such matters. No crude or inapplicable theories should be permitted to prevail here, or evil re- sults will inevitably ensue. These two points — an increase in the number of those in charge of the insane, and providing fire-proof buildings — necessarily involve a greater expenditure than has heretofore been usually appropriated to the construction and management of lunatic asylums. It remains for the sovereign people on the one hand, and the benevolent on the other, to determine whether any alteration in these respects shall be made by the contribution on their part of the necessary funds. j. m. g. QUININE IN THE FEBRILE PAROXYSM. 95 On the Exhibition of Quinine in the Febrile Paroxysm. BY OTIS F. MANSON, M. D., OF GRANVILLE CO., N. C. The introduction of quinine as a remedy in the treatment of remit- ting fever, given in the remission, was perhaps coeval with its discovery as one of the constituents of cinchona, the bark itself having been used in that stage of the disease by Lind, Senac, Clark, Balfour and others, anterior to its disintegration ; but it was perhaps riot more than twenty- five years ago that this salt was administered in the ex- acerbation, and at this time the practice is almost exclusively con- fined, in our own country, to the extreme Southern and Western states. A number of my professional friends in Virginia and North Caro- lina having adopted this plan of treatment, at my suggestion, I have felt it my duty, in compliance with their solicitations, to place within their reach all of the knowledge I possessed on the subject, drawn from my own experience and many others ; and I therefore embrace the opportunity to do so, offered by your flattering invitation to con- tribute to the pages of your journal. Remitting fever has for many years assumed a congestive charac- ter, in the vast majority of instances being attended with the periodi- cal recurrence of a stage of congestion, commonly termed chill; this stage being characterized by a diminution of temperature, varying from a slight coldness at the tips of the nose, fingers and toes, to a fearful frigidity of the whole extremities, and in some few instances a death-like coldness of the whole surface of the body ; these latter cases being termed, par excellence, " congestive fever." Although in many instances this stage is not manifested after the initial chill, by any discernible reduction of temperature in any part of the body for several days, yet it sooner or later becomes apparent to the touch of the attendant, although unfelt by the patient, who, in- stead of experiencing any sensation of cold, is oppressed with intense heat and unquenchable thirst; indeed, we have often discovered the presence of this stage by the increased urgency of his thirst and de- sire for removal of the clothing. At the same time that this coldness of the extreme parts is per- ceived, the rest of the body is of high febrile heat; the pulse quick, fre- quent and small, the breathing laborious, deep sighing, oppression at the praBCordia, pain in the head, loins and limbs, anxiety, nausea and vomiting. After a lapse of time, varying according to the violence of the at- tack, but averaging about an hour, this stage terminates in the ex- acerbation, the heat becomes now diffused over the whole surface, the pulse becomes diminished in frequency, and increased in fulness and force, the pains and thirst still continuing, occasionally, though not commonly attended with delirium and other indications of cere- bral disturbance ; pain on pressure of any of the abdominal regions not generally present in the first exacerbation, but more apparent as the disease advances, especially in the epigastric region. This stage, after a lapse of 24 or 4S hours, according to the type of the disease, 96 QUININE IN THE FEBRILE PAROXYSM. is succeeded by a recurrence of the stage of congestion ; the tongue now becomes sensibly altered, but so variable in appearance that no particular description will apply to it. Evidences of organic irritation in the great cavities, particularly of the stomach, bowels and liver, now become more apparent, and the abdomen becomes tense, tender, and in some cases meteoric. From the fifth to the fifteenth day, the disease terminates, without aid, in 1st, intermittent fever; 2d, fever of a more continued character ; 3d, death. I have deemed it necessary to give this brief description of this disease as it usually appears in my field of observation, in order that the following remarks may be fully understood, as the object of this article is chiefly to display the effects of quinine in this disease. Given in free and full doses of from twenty to thirty grains in the exacerbation, quinine reduces the pulse in frequency, fulness and force ; it removes local determination to the head, chest and abdomen, thereby relieving pain, restlessness, nausea, vomiting and diarrhoea, producing generally a copious, warm diaphoresis, and, in short, to expel fever and " all its dire attendant train," safely, surely and expeditiously, in a period of time varying from four to ten hours from its administration. But along with the employment of quinine the following means are resorted to : Called to a patient in the exacerbation, venesection is practised in every case where the pulse will justify it, but it is rarely that this is called for. In fact, the general experience of myself and confreres is adverse to the use of the lancet in this affection ; the pulse, though often full, and apparently tense, is generally compressible. Local bleeding by cups and leeches will usually be sufficient, and if there is tenderness on abdominal pressure, or other symptoms of visceral implication, these should be freely applied. Should symptoms of cerebral irritation be present, a copious flow of blood will be obtained by cups to the mastoidal regions. This is to be immediately followed by a cathartic dose of calomel, say twenty grains, and in three hours thereafter by twenty grains of quinine, diffused in a wineglassfull of cold water, and if the febrile excitement is intense, thirty grains may be given, but twenty grains will in almost every instance be sufficient for the first dose. Four hours are now suffered to elapse, during which the local bleeding is continued, if required. In this time, in a vast majority of instances, the fever will be considerably reduced, when the quinine should be repeated in doses of six to ten grains every four hours, until thirty -five or forty grains are taken. If in four hours after the first dose has been taken the fever has not sensibly declined, the large dose (twenty grains) may be repeated ; but in many hundred cases the first dose has seldom failed in that time to produce an evident declension of the fever, rendering the after employment of the medicine, in doses of six to ten grains, amply sufficient to effect a complete solution of the disease, the great aim being to throw into the system at least thirty- five or forty grains before the period for the recurrence of the next paroxysm. QUININE IN THE FEBRILE PAROXYSM. 97 In cases attended with obstinate vomiting the stomach should be previously calmed by the administration of forty or fifty drops of laudanum, and if this should be rejected the laudanum may be given by the rectum in double that quantity. But if the gastric irritability should not yield to the anodyne, after local depletion also has been employed as before advised, (and in some cases the stomach will not bear the presence of any medicine long enough to induce its effects,) the quinine must be given by the rectum. One drachm of quinine should be suspended in four ounces of mucilage of gum arabic or thin starch, and given at once as an enema ; to be repeated at the same in- tervals as per orum, and in thrice the quantity above recommended. If, however, the stomach will bear the quinine for an hour, the nausea and vomiting will in almost every instance cease. In some few instances, although the foregoing treatment has been adopted, a slight exacerbation may be perceived towards the next evening ; but this will generally be of brief duration, and will be fol- lowed by a complete intermission, when the quinine may be given in doses of ten grains every morning for three or four days. Although I have described the effect of large doses of quinine in this disease, it will be perceived that I have not proposed to give any name to the group of sequences induced by its action, for the reason that no single term yet designated will denote its peculiar properties ; but the term " sedative," approximates more nearly to its proper designation than any other, and has generally been adopted by the advocates of its employment. I could fill the pages of your journal with extracts from the writings of distinguished physicians of our own country to corroborate what I have stated, but, instead of doing so, must refer the skeptic to our Southern and Western journals. To those who have observed the action of this remedy in the dif- ferent modes and various conditions of the system in which it is ad- ministered, the inference is irresistible, that its effects are solely de- pendent upon its salutary action on the nervous system. This effect is so often immediate, arresting the disease at once, before it could be absorbed in the blood, or resolve inflammation, that we are compelled to regard its action as purely nervous. Now if it be contended that this fever is merely symptomatic of gastro-enteric lesion, none will surely argue with Broussais that quinine arrests the febrile movement by its local application to the inflamed surface ; that it has any power to effect this, has never been demonstrated, and is opposed to the expe- rience of all. Or if it be contended with Liebig, that in fever some of the elements of the brain az~e removed which are supplied by the alkaloids of bark, &c, we may reply, that prior to this restoration of the lost elements of the cerebral substance, the agents have to be sub- jected to the functions of absorption and nutrition, both so imperfectly conducted amid febrile excitement, and for the performance of which a far greater period of time is necessary, even in health, than is am- ply sufficient for the sanatory action of quinine. These conflicting, but ingenious theories of two great minds, only serve to make the " darkness visible" that surrounds the essential nature of disease and its remedies. 98 QUININE IN THE FEBRILE PAROXYSM. The effect of quinine upon the pulse is one of the most remarkable of its powers in this disease. I have reduced the pulse from 140 and 150 pulsations in a minute to its normal standard in six hours. In- deed I have in several cases desisted from its continuance, for fear that its sedative effect might be carried too far. The organic lesions, therefore, so often developed in the course of this fever, so far from contra-indicating its use, are certainly relieved by it, or their cure ac- celerated. Where blood-letting, both general and local, assisted by the other usual antiphlogistic measures, have failed in arresting cerebral inflammation, quinine in a few hours completely arrested the pro- gress of the disease, reducing the pulse, calming delirium, promoting free diaphoresis, and inducing sleep, from which the patient would awake to speedy convalescence, quinine would seem to effect this by allaying the morbid excitement of the nervous system, upon which this increased action of the heart and arteries is dependent, and from the continued excitement of which the organic lesions developed would seem to arise. It will need but a short experience with this article to convince the careful observer that it possesses the power of allaying nervous irrita- tion, spasm' and pain. Neuralgia, whether intermittent or continued, will almost invariably yield to its sedative and anodyne properties. Those to whom the facts and views herein set forth are entirely no- vel, may here enquire, " If there is no danger in administering quinine during febrile and inflammatory excitement?" Confining my reply to this disease, I unhesitatingly answer, " That there is no danger when given in full and free doses, in the manner which I have indicated !" They may also enquire, " Have all authors on therapeutics committed an error in classing quinine amongst the excitants, in fact, as the 6rst and most valuable of tonics ?" To which I reply, that all of the standard authorities on this subject I believe to be perfectly correct ; but their knowledge of quinine is confined to its tonic, stimulant and antiperiodic character, as it assuredly is in small, repeated doses, but given in large doses it produces the effects I have described ; and therefore not only admissible, but indispensable where small doses would not only be improper but pernicious. I speak from great expe- rience with this article. I have given 60 ounces in one fall, (1846,) and I here declare my belief that armed with this agent, remitting fever, if attacked early, is as certainly and completely under its con- trol as ague. I have given it in the chill, the height of the paroxysm and its decline, complicated with indisputable evidences of lesion of the cerebral and abdominal organs, without any injurious effect in any case ; and to sum up in few words, the sulphate of quinine in full doses allays pain, irregular nervous action and restlessness, diminishes the pulse in frequency, fullness and force, removes local determination and equalizes the circulation, by allaying that morbid excitement of the nervous system upon which remitting fever depends, and conse- quently relieves the local lesions arising from this exalted action of the circulation. " Heec certamina tanta Pulveris exigni factu compresa quiescunt." HASKINS' CASE OF DOUBTFUL SEX. 99 Report of a Case of Doubtful Sex, BY WM. D. HASKINS, M. D., OF RICHMOND CITY. [Communicated to the Medical Society of Va.] In September 1850 I examined by request a slave belonging to a gentleman in Mecklenburg county, Virginia, who had been reported as "A curious case of Hermaphrodism," by Dr. S. H. Harris, in a com- munication made to the 27th Number of the American Journal of Medi- cal Sciences. In the lower orders of organized bodies hermaphrodism is common ; indeed, in vegetables it is so prevalent as to have led some to suppose it to be an attribute of the order; and the more nearly the other class of beings approach the vegetable, the more common is this combina- tion of sex. But it is now admitted by nearly all those who have investigated the subject, that no such phenomenon ever existed in the human species as a perfect hermaphrodite, although there are numerous instances of preternatural structure which give the appearance of a double sex. This slave I found to be an instance of this kind ; and, as the report of Dr. Harris was calculated to produce a different im- pression, I have thought it of sufficient importance to justify a re-de- scription. I must say, injustice to my friend Dr. Harris, that the examination which I was enabled to make was much more satisfactory than the one from which he made the report. His having been made at a time when he did not expect it, he was unprepared with instruments to assist him, and had also to contend with the reluctance which is usually manifested by such persons to have their real situation known. In this instance, nothing but the authority of a master whom he (adopt- ing the masculine pronoun when referring to the case) greatly feared could induce him to submit to an examination. Anticipating this difficulty, I approached him in a different manner from that resorted to by Dr. H. 1 met him alone, as it were acci- dentally, and told him that his situation had been described to me, and I doubted not, from what I had heard of it, that he could be re- lieved, and if he would confide in me I would promise to observe the strictest secrecy. By this means I succeeded in inspiring him with confidence, and arousing a hope that his difficulty could be removed, whereupon he became communicative, and readily submitted to an examination. There is nothing very peculiar in his appearance that would arrest attention, until you are told that there is some doubt as to his sex, when it at once occurs to you that his appearance is that of a woman dressed in man's apparel. This conviction is forced upon your mind by observing his stature to be low, frame delicate, hips broad, lower extremities bent or inclined inwards at the knee joints, making him knock-kneed, gait shuffling, instead of the firm, strong, elastic step of manhood, face perfectly smooth, exhibiting no trace of beard, although he is now 21 years old. Opening his bosom I found the mammas, 100 HASKINS' CASE OF DOUBTFUL SEX. although not exhibiting the plumpness of virginity, as well developed as you ordinarily see them. Upon exposing the genital organs, how- ever, there is presented a very curious condition of things. The mons veneris is prominent and well developed, being covered with hair as in the female, and immediately over the symphisis pubis is situated an organ which resembles almost exactly a dwarfish penis. It is about an inch long and half an inch in diameter, is terminated by a tubercle corresponding in shape and appearance with the glans jjenis. There also appears at first sight to be the orifice of an urethral canal, properly located in the glans, but upon closer examination it proves to be the terminus of a fissure situated on the inferior surface of the organ, formed by the approximation of the edges of what appears to be the nymphae, which had adhered to, and were stretched over it, so as partly to contribute to the formation of a preputial covering. The prepuce, I may say here also, consisted of that portion of the labia majora which was separated by the root of the organ, as well as the lower portion of the mons veneris. Drawing back this organ upon the mons veneris, I introduced a silver probe along the fissure before alluded to, to the distance of about an inch below its root, where the fissure terminated by the apparent union of its lips, form- ing a cicatrix, which resembled somewhat the raphe of a scrotum. This raphe extended to what should have been the position of the posterior commissure of the vulva in the female. Directing my at- tention again to the point where the fissure terminated, I endeavored to find, with a probe, the orifice of the urethra, which I supposed existed at or near this place ; in this I was not mistaken. I then took a, female catheter, and introduced it into the bladder, and there es- caped through it about a teacupful of urine. Withdrawing the ca- theter and inserting it again, at a point a few lines below the orifice of the urethra, I gave it a direction downwards, instead of that of the urethral canal, and found no difficult}7 in inserting it its whole length into a cavity where its point could be freely moved in any direction. Taking it out, the lower portion was filled with a dark-colored fluid resembling blood, and I doubt not, was the menstrual fluid which had there accumulated. The lower portion of the labia externa presented a rugose, flabby appearance, and with the raphe or cicatrix dividing them, resembled very much a scrotum deprived of testicles. This condition of the labiae was doubtless produced by the collection behind them of the fluids escaping from the womb, causing them to act temporarily as the outer walls of a sac containing fluid, the pressure of which varied with the positions of the body. There was evidently a considerable quantity of this fluid in the vagina at this time, as was indicated by the height to which the catheter was filled when withdrawn. I learned from the individual himself that its escape from the vagina was irregular and depended upon the attitude of the body, the only- outlet being the small orifice just beneath the urethral opening through which the instrument was introduced. There were, however, regular periodical returns of all those symptoms which accompany menstrua- tion, and so marked were they as to have attracted the attention of BROOCKS' PENITENTIARY CASES. 101 the elder female servants in the family. I also learned from him that his penis (as he supposed it to be) was subject to erections, and that he had desires for the female sex, but had been deterred from attempt- ing connexion by an apprehension that his deformity would be dis- covered. As regards the former of these statements, it is not at all inconsistent with our knowledge of the structure of the clitoris ; for all anatomists have described it as consisting of erectile tissues like those of the penis, and subject to similar orgasms. The latter I think has been satisfactorily accounted for by Dr. Harris, who supposed it to be the results of education : " He having been taught from child- hood up to look upon himself as a male, now, in imitation of others, deports himself as such to the other sex." Thus it appears that this " curious case of hermaphrodism," has been deprived of all its mystery, and proved to be nothing more than a case of occlusion of the vagina, accompanied with hypertrophy of the clitoris. An operation was proposed ; but when I informed him that it would entirely change his assumed sex, and make him a woman, he opposed it with so much earnestness that it was not insisted upon. Cases Treated in the Armory and Penitentiary Hospitals, With Remarks. BY JOHN N. BROOCKS, M. D., SURGEON TO THESE INSTITUTIONS. Case I. — Osteosarcoma. M. Beasly, a mulatto and convict in the Virginia penitentiary, has been in the prison 5£ years, was sentenced for 12 years, and was ad- mitted into the hospital the 27th of October 1846, aged 42 — his health was good and his habits intemperate previous to his conviction. He said his mother had a cancer on her breast when he was ten years of age, which was excised, and there was no return of it. One of his brothers had a white-swelling on his foot at the age of 12 years, and lost several bones and recovered. He recollected to have fallen down a precipice when intoxicated, some 12 years since, and striking his head against a large stone, from which he received a considerable shock, and was for a time in a state of insensibility. He has for the last three years had frequently slight pain in his jaw, so slight how- ever, as not to give him any uneasiness until last March, when it be- came more violent and assumed a more serious character; sometimes acute and lancinating, and at other times dull and aching, and at no time free from pain. His gums became spongy and insensible to the touch, and often bled copiously. There was no marked change in his condition until June following, when he had a tooth extracted from the affected jaw. Its root was decayed. This gave him no relief. The gums continued to swell and to bleed. His face commenced swelling in September, and the tumor became hard and unyielding to pressure. The remedies administered had no influence on the pro- gress of the disease ; and in consultation with Drs. Cunningham and 14 102 BROOCKS' PENITENTIARY CASES. Deane, it was decided that no benefit could be afforded by an opera- tion, and that, it would be cruel to perform one. The remedies used were principally the different preparations of iodine and opium inter- nally, and soothing and emollient applications to the tumor. The disease, in its uninterrupted progress, involved the whole of the right superior maxillary bone, and extending to the eye, destroying it and shooting up a fungus from its orbit. The tumor attained to the size of a man's fist — it was irregular and lobulated. He died the 3d of December. Autopsy the next day in the presence of Dr. Cunningham and my- self, by Professor J. Wyman, who was so kind as to make it for me. " The disease was found to be a malignant tumor of the upper jaw, involving principally the antrum extending to the orbit of the eye, de- stroying the floor, the outer walls and part of the roof. The malar bone had entirely disappeared, also the alveolar portion of the maxil- lary bone behind the bicuspid teeth, and the palatine process nearly to the median line. The interior of the tumor was disorganized and in a gangrenous condition." Remarks. — The prognosis in this disease is always unfavorable. When once developed, we have no reliable means of arresting its progress ; our treatment, therefore, is necessarily palliative. — limited to such remedies as are best calculated to alla}r irritation and to soothe the pains of the suffering patient. Should an operation be resorted to, in most cases the disease will return and seize upon some more vital organ and hasten the dissolution of the patient. We are as yet almost entirely ignorant of the causes of this most malignant affection. It has been attributed to syphilis, to rheumatism, to hereditary taint, to cancer, to local injury, and in many cases no cause can be assigned for its production. It may attack any of the tissues of the body, but it begins usually in the periosteum and the cancellated texture of a bone, and its distinctive and pathognomic characters will be modified by the part affected and the constitutional tendencies of the subject. The antrum, the alveolar depressions of the jaws, the palatine bones forming a part of the roof of the mouth, the floor and the sides of the nostrils and the floor of the orbit, have been found to be most fre- quently the seat of this disease. All ages and both sexes are liable to this disease, but it occurs more frequently from infancy to forty years of age. Case II. — Scirrhns of the Stomach. W , of the public guard of Virginia, and formerly in the United States' service, age 55, constitution had been greatly impaired by exposure and by previous intemperance, was admitted into the armory hospital the 13th of November 1848. He had torpid liver and catarrhal symptoms, with pain of right side. I ordered cups to be applied to his side, and ten grains of calomel and rhubarb to be given him. 14th, tartar mixture; 15th, alterative doses of calomel and ipecacuanha every four hours ; 16th, had pain of stomach — cups to epigastrium and flaxseed tea for drink. 17th, blister to stomach, BROOCKS' PENITENTIARY CASES. 103 powder at night. 19tb, stopped treatment. Dec. 10th, pain of side returned. Cups were applied to his side, and five grains of calomel and fifteen of rhubarb were given. 11th, blister to stomach and three grains of calomel at night. Anodyne and alterative doses of calomel were directed to be given pro re nata, until the 18th, when he com- plained of a burning sensation in the stomach. Gave him lime-water and milk. This was continued until the 31st, when he thought he was able to go to duty, and was discharged on that day. From the persistence of this sensation in the stomach I now suspected that or- ganic changes were in progress, and that scirrhous degeneration was going on in the stomach. I gave him this opinion, and suggested to him the propriety of being discharged from the guard, and of obtain- ing some employment on a country farm, as better calculated to ren- der his condition more comfortable and to prolong his life. Being entirely dependent on his pay in the guard, and hoping that he would soon be better, he was unwilling to follow my advice, and preferred to remain longer in the company. January 22nd, 1849. He returned to the hospital with increased burning of the stomach. Ordered cups to the stomach, and lime- water and milk. The lime-water and milk produced a very soothing effect, and was continued until the 30th, when I discovered a pulsating tumor in the epigastrium and in the region of the cardiac orifice of the stomach. I directed him to keep perfectly still, and to continue the lime-water and milk. On the 31st I made a careful stethoscopic examination, and found that it was not an aneurism. As the distin- guishing characters of this disease were not observed, it was my opi- nion that it must be some indurated body lying over the artery, and received its pulsation from the artery beneath ; and from the history of the case and the location of the tumor, I supposed that it was scir- rbus of the cardia. The soothing and anodyne treatment was directed to be pursued, and five drops of a solution of iodo-hydrargyrate of potassium to be given three times a day in water. In a few days the tumor began to change its seat and gradually to move to the right side, until it reached the region of the pyloric orifice of the stomach, and it remained there. Regarding it to be a very interesting case, I invited several of my medical friends to see it with me at different pe- riods of the disease, and at different stages of its transition. Drs. Mi- nor, Nelson, Gibson and Haxall saw it ; the former, when it was loca- ted in the epigastric region and pulsating; the latter, when in the py- loric region without pulsation. Dr. Gibson saw it when about mid- way between these points. The iodine and anodyne treatment was continued, with an occasional enema and other auxiliary remedies, du- ring its progress, as they seemed to be required. He died on the 16th of April. After eating, he suffered great pain for some months before his death; and a short time before he died, he vomited and passed a large quantity of a dark, offensive, glutinous mass which adhered firmly to the vessels, and was of a coffee-ground color. On the next day, the 17th, I made the autopsy in the presence of Drs. Haxall and Minor. The stomach was found to be greatly enlarged and distended with a fluid of a gruelly consistence and color — its coats very much at- 104 BROOCKS' PENITENTIARY CASES. tenuated, and its mucous one softened and disorganized, and could be readily detached with the handle of a scalpel. The pyloric orifice was scirrhous to the extent of an inch or more, and it would admit the end of the little finger if slight force was used. The other organs were not carefully examined, they, however, on a superficial view, had a normal appearance. Remarks. — How long this disease had existed, I have no means of deciding. He had been infirm and in delicate health for some years, complaining mostly of dyspepsia, biliary derangement and costive- ness, but was enabled to attend to his military duties. The most remarkable feature in this case, and one for the solution of which I can offer no satisfactory explanation, was the change in the seat of the tumor. He was extremely emaciated and almost ex-sanguine, and his death was evidently caused by starvation, his stomach not being in a condition to digest and assimulate food sufficient to sustain life. Case III. — Lumbar Abscess. of the public guard of Virginia, age about 45, constitution delicate ; had been intemperate ; was admitted into the armory hos- pital the 1st February 1850, with pain and slight swelling of his left foot ; both pain and swelling soon disappeared by the application of poultices and the use of salts. On the 15th, he had the ordinary symptoms of catarrh, for which I prescribed tartar mixture and cups to his temples for pain of his head. 14th, gave him 10 grs. calomel and rhubarb ; 16th, tartar mixture ; 17th, salts ; 18th, had pain of loins, directed cups and gave dose of salts ; 24th, pain of loins con- tinuing and extending to hip, and down the thigh and in the left groin, with some swelling in the groin ; the pain was increased by extending the limb ; gave 30 drops wine of colchicum three times a day ; 26th, Dr. Haxall saw him for me, (I was out of town ;) hip bath and 10 grs. Dover's powder were ordered; 27th, retention of urine. Cathe- ter introduced ; colchicum, 25 drops to be given in a tablespoonful of hyd. potash mixture morning, noon and night. March 1st, I saw him, he complained more of his back, directed blister to loins and 10 drops of a solution of iodine and hyd. potash three times daily; 3d, had con- siderable fever and violent pain in his hip and thigh, his suffering was very great, especially at night — ordered cups to hip and 10 grs. calomel and 6 Dover's powder, and the part to be covered with a warm poultice ; 4th, 5th and 6th, lime-water and milk for sickness of stomach, and introduction of the catheter for retention of urine on the 4th. March 7th, colchicum ; 9th, iodine solution and 6 grs. of Do- ver's powder at night ; 10th, retention of urine, introduction of the catheter, and salts in the morning and Dover's powder at night. Re- tention of urine again occurred and required the introduction of the catheter. In every instance in which laudanum or Dover's powder was administered, this effect followed ; 11th, some ardor urinae, gave juniper berry tea ; 12th, cups to hip; 14th, hip bath morning and evening and colchicum ; 16th, blister to hip, and colchicum ; ISth, 5 grs. hyd. potash three times a day, and 40 drops of laudanum, with BROOCKS' PENITENTIARY CASES. 105 the same effect on the function of the bladder. I had again to intro- duce the catheter — hyd. potash was continued until the 22d, gave 10 grs. calomel and rhubarb, and directed vol. liniment to be applied to the hip and thigh ; 23d, vol. liniment and colchicum. April 1st, had diarrhoea, directed acetate of lead and opium in pill every two hours, until it should be arrested ; 22d, abscess pointed in the loins over the crest of the ilium, and fluctuation was very perceptible. I made a free opening with a lancet — a large quantity of pus escaped and the pain was greatly diminished ; 23d, matter had continued to flow very profusely, and the patient a good deal debilitated, with some sensation of chilliness — gave infusion of bark and spirits mindereri. From this time his condition required a supporting system of treatment, and a more generous and nourishing diet was ordered. To permit the mat- ter to escape freely, and to prevent its being at any time confined, I was very careful to keep the orifice free and open. For months large quantities of matter, sometimes mixed with blood, were discharged — hectic fever came on, and he became very feeble and greatly ema- ciated ; poultices were kept constantly applied to the loins. July 10th, I ordered quinine and porter freely. About the middle of Sep- tember the discharges of matter ceased — the wound healed, and his improvement was rapid — he was discharged from hospital treatment the 18th of October, and is now, (January 14th, 1851,) perfectly well and attending regularly to his duties as a soldier of the guard. Remarks. — This was a case of very great suffering until the pointing of the tumor and the liberation of the matter by the lancet; indeed, medicine seemed to have had little or no influence in alleviating his suf- ferings. The pain appeared to continue unabated, regardless of the remedies used — opium, apparently, had an effect which I never wit- nessed in any other case, that of taking from the patient the control over the function of his bladder. As this occurred so frequently, and invariably after its exhibition, and at no other time during his long ill- ness, and as no obstacle was ever found to the introduction of the ca- theter, I am constrained to believe that the retention was induced by the opium acting in some way upon the nervous system. This is, fortunately, a very rare disease in America, for according to high authority, "very few patients recover from this disease under any circumstances, and those that escape remain puny and debilita- ted." Up to 1S27, Dr. Physic never saw but one case in this coun- try " unconnected with disease of the spine." Case IV. — Traumatic Tetanus. John C. Bryant, aged 31, had been in the prison more than 3 years, of previous imperfect health and intemperate habits. He was sentenced for 15 years — whilst drawing water from the well in the yard, he had vertigo and fell, and was caught in the massive wheel attached to its machinery, and received a compound fracture of the right fore-arm, (both bones broken,) and several wounds of the face and scalp, on the 17th of September last, and was brought to the hospital — the wounds were dressed and proper splints were applied 106 BROOCKS' PENITENTIARY CASES. to the limb. He appeared to be doing well up to the 28th, when I observed some swelling of the arm, blisters on the hand, and a slight bluish color. I took off the splints and bandages, and found that the bones had not united, and that a large quantity of matter had formed within the two days past — since which time I had made an examina- tion. This rendered farther effort to save the limb unsafe, and it was thought advisable to resort to immediate amputation as the only means of preserving his life. 1 requested Dr. Marx to assist me in the ope- ration. After examining the case, he concurred with me in its pro- priety and necessity, and in the morning of that day, assisted by him, I amputated the limb some 3 or 4 inches below the shoulder joint. He bore the operation well, and under the use of brandy his sj^stem reacted perfectly. After the dressings were applied he suffered scarcely any pain, and enjoyed some sleep. It was very warm weather, and several of the windows of the hospital were up, and a light coverlet placed over him. A decided change took place in the night — it turned suddenly cold, and before the change was observed he was chilled. 29th. — When I saw him, his jaws were firmly locked, so much so as to resist considerable force to open them — his pulse was soft, rather weak, and more frequent than usual, and his surface was covered with slight perspiration, and he complained of pain in the region of the sternum. I caused him to inhale ether, and in a short time he could open his mouth partially — cups were applied to the spine, and a flax- seed poultice to the stump — 3 i. tincture opii. was directed to be given every 2 hours until drowsiness or sleep was produced, and if he should be unable to swallow, 3 ij of tincture opii. was to be given by enema every 2 hours, and to keep him under the influence of ether by its occasional inhalation, and 20 grs. of calomel were given. Sleep was produced : and whilst he was sleeping the muscles were relaxed, and his mouth remained wide open ; but the instant he awoke the spasms returned, and would snap the jaws violently together, and they would remain firmly clinched until he again fell to sleep. 6 o'clock, P. M., the spasms increased in violence, and the muscles concerned in respiration so powerfully contracted as to threaten suffocation. I directed a blister 3 inches wide to be applied to his spine its whole length, and a cathartic and an enema during the night, unless his bowels were moved. Finally, the spasms of the respiratory muscles became so great as to arrest this function, and he died at 9 o'clock, P. M., with the symptoms of strangulation. Remarks. — The pathology of tetanus is very obscure, as is the case with the diseases of the nervous S}^stem generally. Most writers, however, I believe, regard the spinal cord and the afferent nerves to be most affected, and the brain not to be involved. In the cases which have come under my observation, there was no evidence of disease of this organ. Pathologists agree in the opinion, that the spinal cord is either irritated, inflamed or congested. The treatment of this disease has been very unsatisfactory in its results. We occasionally see reported in the periodicals of the day cases cured by different modes of treatment, but all such cases followed very slight injuries, from which the system had sustained but little shock, and the conse- bolton's case of ovariotomy. 107 quent irritation not great or of long continuance. I have never seen any case reported as cured, where the primary injury was great and the system received a considerable shock ; and hence the universal testimony of the army surgeons is, that all cases are fatal in their ex- perience. They meet with cases occurring after gun-shot wounds, and other serious injuries. Before we can hope to contend successfully with the diseases of the nervous system, we shall have to learn more of the laws which control its movements; and as interesting investi- gations are now in progress, we do not despair that some gifted mem- berof our profession may not yet be enabled to elucidate its forces and to indicate the means with which its diseases may be made more obedient to treatment. I do not regard opium as a curative agent in the treatment of this disease, but as acting beneficially, by allaying irritation, moderating the spasms, and preserving the vital powers un til cups, blisters, purgatives and other remedies can act upon the spi- nal cord. I advise ether for the same purpose, and I believe it to be more efficient than opium. N. B. With the exception of the treatment, of which I took notes at the time, the above cases have been reported from memory. January 1851. A Case of Ovarian and Peritoneal Dropsy. Paracentesis during period of eight months and a half— Attempted ex- tirpation— Failure — Death on 23d day — Autopsy. By James Bol- ton, M. D. June 25, 1849. N. G., aged 39 — living in concubinage, never pregnant. Saw her in consultation with Dr. C. B. Gibson. She had previously been under the care of Dr. John Cullen, and had taken, by his advice, large quantities of iodide of potassium, iodide of iron and sarsaparilla, besides applying active counter-irritation to abdomen. Present condition. — General debility ; disturbance of respiration and digestion; great enlargement of abdomen, with regular contour in both upright and horizontal positions ; distinct fluctuation. Careful manipulation proved existence of tumors in both iliac, and pubic regions ; percussion exhibited some symptoms of peritoneal, and some of ovarian dropsy. Treatment. — Tapping below umbilicus ; — 9 quarts of greenish, te- nacious serum drawn off. Effects. — Very great relief; tapping borne very well ; iliac and pu- bic tumors very distinct. July 13. — Uterine examination per vaginam — os and cervix uteri healthy and normal, pelvic cavity rilled with tumors. She menstruated a few days previously, and has done so regularly. August 9. — Second tapping, with results similar to those of first; general health much improved. September 25th. — Third tapping. October 28th. — Fourth tapping. 108 bolton's case of ovariotomy. November 2d. — Left tumor much enlarged ; tapping in left iliac region ; — nearly two quarts of semi-purulent fluid, probably from ovarian cyst, drawn off. Nov. 30th. — Fifth tapping below umbilicus. Dec. 1st. — Sixth tapping, about an inch above umbilicus, drew off nearly a quart of fluid similar to that from iliac region. Dec. 25th. — Seventh tapping, below umbilicus. 1850, Feb. 3d. — Eighth tapping, below umbilicus, also above umbili- cus, and in left iliac region ; at all three places in immediate succession. March 4th. — Ninth tapping, below umbilicus, and immediately after in left iliac region; fluid from latter having at first a reddish, limpid appearance, but afterwards its usual color and consistence. Patient not relieved as usually ; complains of distressing pains in right lumbar and hypochondriac regions, which are filled by a firm tumor ; obscure fluctuation ; two deep punctures with grooved needle did not reveal existence of fluid. Patient decidedly cachectic ; has been falling into this condition daring the past month. March 10th. — At the urgent request of patient and friends, Dr. Gibson attempted extirpation of tumors, assisted by myself, Drs. C. P. Johnson and A. E. Peticolas. Ancesthesia produced in 10 minutes by about 3 ij. chloroform, and effects very favorable — sustained about 25 minutes by an additional 3 i. chloroform. Operation. — Incision in course of linea alba, commencing 2 J inches above umbilicus, passing on right of it nearly to symphysis pubium ; considerable thickness of adipose tissue, peritoneum much engorged and thickened ; on opening this membrane a large quantity of fluid gushed out; intestines extremely flaccid, tumors occupying both iliac regions, pubic, both lumbar and extending into hypochondriac ; ex- tensive adhesions to walls of abdomen and intestines ; pelvis filled with tumors; cauliflower excrescence on apex of right tumor. Opera- tion abandoned ; wound closed with interrupted sutures and adhesive plaister ; strip of linen soaked in collodion laid over all, and well sealed at edges with collodion to exclude air. Nausea produced by chloro- form continued during the day : pulse feeble — ?-- Gum camphor, gr. ij., and morph. sulphat. gr. J, pro re nata. 11th. — Passed night pretty well; nausea, prostration of strength; no tenderness of abdomen ; riced barley water. — B- Emplast. sinapi, ad. epigast. 12th and 13th. — No material change. 14th. — Much improvement ; wound closing ; large, ill-looking fun- gus protruding just above umbilicus ; fistulous opening above it, from which fluid of ascites drains. 23d. — Continued in much the same condition until to-day ; dis- charge more fetid with cadaverous order. April 3d. — Symptoms gradually worse ; loss of strength ; tumid abdomen, without tenderness on pressure. Died 24th day from operation. Sectio cadaveris. — Large quantity of fluid gushed from peritoneal cavity ; ovarian tumors filling pelvis and most of abdomen ; all these contained fluid varying from a watery consistence to that of cream, and from a light greenish tint to a yellowish color ; their surfaces pre- EDITORIALS. 109 sented in some places the appearance of granulations or cauliflower excrescences, and in others, of cerebrifbrm matter. The uterus was healthy, and not enlarged. Remarks. — That the operation of ovariotomy may be performed with safety, any one who will take the trouble to consult the reports, particularly of the last few years, may soon satisfy himself. That it is extremely hazardous, is admitted. The question then arises, is it justifiable ? I answer unhesitatingly, as in all other like cases, an ex- tremely hazardous operation is justifiable for the purpose of curing a fatal disease. Acting simply upon the doctrine of probabilities, the patient has a right to demand that course which gives the best chance for his life, and the physician is bound to recommend it. This principle is admitted continually in the various capital operations. The writer has known an instance of recovery after amputation for dry gangrene, which was extending. The operation had been declined by several surgeons, who abandoned the patient to his miserable fate. In the present instance the opinion was very properly unfavorable to the success of the operation. The tumors were known to be nu- merous and extensive, and there was reason to believe that adhesions existed. The patient had been gradually declining during the pre- vious month. She was believed to have reached that point in the course of her disease when she must inevitably sink in a short time, unless she could be rescued by an operation. If the attempt were delayed any longer, she would soon be beyond the reach of art. At this critical period the whole case was fairly laid before the patient and friends, and their decision was adopted. Although the case ter- minated fatally, I believe that decision was correct. J. B. lIDfflTOIEMJLf The Stethoscope. It is a pleasant duty to acknowledge the debt of gratitude which we owe to the public press generally throughout Virginia, for their flat- tering notices of our first issue, and their commendations of our en- terprise. We would be pleased to exchange with many who send us their paper, but we must be denied the pleasure of doing so, be- cause the wise governors of the land have not deemed the periodical literature of sufficient importance even to allow us the poor privilege of exchanging, even with one another, free of postage. Newspapers noticing us will be thankfully received. The Stethoscope has met with a reception among the physicians of the state, which, in cordial welcome, far exceeded our expec- tations. It would be very agreeable, if time permitted, to answer the 15 110 EDITORIALS. many letters we receive daily from our brethren, cheering us on in our labors. If they be an indication, then we are proud to have es- tablished a work which meets with their approval. If our success seemed problematical at first, it is no longer so ; and for the infor- mation of those who may have waited to subscribe, to see if we would succeed, we feel warranted now in assuring them that we have suc- ceeded, so far as to place it beyond the shadow of a doubt that our work is permanently established, and they may now safely forward their names as subscribers. We would here call attention to a necessary rule — that subscrip- tions must be taken by the volume and not the year, unless the edition of back numbers is exhausted ; and the sooner we are furnished with the names of those who intend to become subscribers, the sooner will we be enabled to make permanent arrangements as regards the number of copies to be printed. It is proper to say, that it was deemed more advisable to throw the advertisements on the last two leaves than to have a double cover. This we hope no one will complain of, as we are entitled to a fly leaf of the same size whereon to string out the contents, as is done in many publications. Moreover, upon comparison, we find that our sixty pages contain more matter than any sixty-four page monthly medical journal in the United States ; and a cotemporary has noticed us as the cheapest journal out. Our size and cheapness render two things necessary. First, a large quantity of original matter ; and as we believe the principal contri- butions from our section will be furnished for publication here instead of sending them away, we do not fear a lack of them. We again call upon every practitioner in the country to send us details of his interesting cases, in letter form, if preferred. Original articles will be preferred to selections, even though they occupy a very large pro- portion of each number. The second necessary is, a large subscription list. The size and price render a full list necessary to pay expenses ; and it must be very large to be the source of any profit, after bestowing the time and labor upon it requisite to edit a monthly journal. Our original matter has so completely filled up the present number, that it is necessary to defer many selections as well as other things of importance. Readers, doubtless, will find no objection to this ; we ourselves hope that it may be frequently the case. EDITORIALS. Ill The article of Dr. Merritt on congestive fever, from its length, has excluded much other matter from our present issue. It may be deemed prolix by many of our readers, but as the subject of which it treats is one of great practical importance and is a disease of the South, we have departed from a rule we have adopted, not to give up so much space to one subject. We commend the article to a careful perusal, as it comes from a gentleman who has enjoyed great expe- rience in a region of country where congestive fever is a prevailing disease. Our Exchanges. In addition to the list announced in our January No., we are in re- ceipt of the following medical journals. There are others which we would like to have on our list, but which have not been sent to us — among these is the American Journal, &c. The Charleston Medical Journal and Review, bi-monthly, handsomely published, and containing much good matter, which we have not room to notice. The New Jersey Medical Reporter and Transactions of the N. J. Medi- cal Society, edited by Dr. Joseph Parish, Burlington. Our thanks for its notice of us are due. American Journal of Insanity, published quarterly by the N. Y. State Lunatic Asylum. The three last numbers received. The Medical Examiner. — This popular monthly is now entering on its seventh volume, and we believe its popularity is increasing daily. The New Orleans Medical and Surgical Journal, bi-monthly, edited by Dr. A. Hester. Its first article is 30 pages long, being a portion of an article on congestive fever, by S. Ames, M. D., of Montgomery, Alabama. It contains much other valuable matter. The Philadelphia Lancet, (first two numbers) — a quarto of six page* of matter, semi-monthly, edited by Dr. Thomas Dunn English. We thank the authors for several introductory addresses, among which is one from Dr. Horace Green, Prest. N. Y. Medical College and Prof. Prac. Med. This address abounds in high-toned sentiment, and merited the honor it received of being published by the class. We have received a paper on " The Curability of Consumption, con- sidered in reference to a new method of ascertaining the disease of the lungs," &c, from the author, Dr. M. Mattson, fellow of the Mas- sachusetts medical society. This new method is to ascertain the vital 112 EDITORIALS. capacity of individuals, or the amount of air which they can inspire, by means of an instrument called the spirometer. This paper was published in the Boston Medical Journal, and is one which will doubt- less elicit some examination into the subject wherever it is read. We think the author underrates auscultation and overrates the new method. Our reception by the medical press generally has been very flatter- ing ; and, considering that we are somewhat of a greenhorn as yet, we have been fortunate in not drawing down more raps over the knuckles than we have. The Boston Medical Journal complains and justly, that we " cut down his number of pages one-fifth," &c. We make the amende honorable with pleasure. That sheet has twenty pages, and of good matter too. As to the " withholding the modifying circumstances respecting the colored students," &c, it is unimportant. The me- dical faculty of the Harvard University now announce that in future colored men will be excluded from their classes. The marriages of other doctors than those of Massachusetts are published in the Jour- nal. We stand corrected, and as a bachelor, it is a matter of some interest to us. The plan is a good one ; for it informs many of the advance in life made by their old classmates, though distant and almost forgotten. The New York Medical Gazette thinks hard of our saying that Vir- ginia is destined to become the seat of medical learning for the South, &c. Now, in the same number, we find the following most sanguine pre- diction and in italics : " In ten years, the seat of medical learning in Ame- rica, since the establishment of the Republic, claimed by Philadelphia, will be transferred to the great metropolis." Still we think we have as much right to hope and expect to say why Virginia will be the medical cen- tre for the South, as our friend has to prophecy that New York will be the great centre of medicine in America. As for the medical colleges further South, we wish them the greatest possible success. And if they exert themselves, we believe that in a twelvemonth the editor of the Gazette will not congratulate himself " that there are now several hundred Southern students at the North, and a large proportion of them from Virginia." Tilden & Co.'s Extracts. We have received ten samples of different extracts, prepared by Messrs. Tilden & Co. of New Lebanon, N. Y. They are beautifully put up in half pound bottles, each cased in a box, and hermetically EDITORIALS. 113 sealed. We thank the manufacturers for the present, but a proper examination of them will tax our time just now more than can be afforded. However, they shall be duly examined and reported on as early as possible ; and, like all such things, will be dealt with accord- ing to their merits. Suffice it to say for the present, that they come highly recommended from many good sources, and purport to be pre- pared in a different manner and a more scientific one than that usually adopted. They are prepared in vacuo, at a very low temperature, thus the active principle of the vegetable is retained in an unimpaired and concentrated form. We have examined the extract of conium before us. It is refined, and deprived by a peculiar process of its coloring matter, of chlorophylle and albumen, which are liable to de- compose and prevent its keeping well in humid climates. Messrs. Tilden & Co. are spoken of on all sides as being thoroughly competent and prepared to produce articles in every way equal to those which are now imported ; and if they will carry out their " in- tention of supplying the profession with such preparations as can be entirely relied on," these extracts will be very generally used through- out the country, both because they will be cheap and convenient. Messrs. Purcell, Ladd & Co. are Tilden's agents for Richmond. The Medical Society of Virginia — Act of Incorporation. We would call the attention of every physician in Virginia to the subjoined charter and constitution, and the important by-laws of the Medical society. It will be seen that the whole profession can and should be enrolled, and that a county and state organization, which would benefit individually every member of it, can be most easily ef- fected by the establishment of branch associations. Our want of space renders it necessary to defer a fuller notice of it, but meanwhile we hope to see a continuance of the rapid increase of its members, from every county, which has been steadily going on, and in another year we confidently expect that it will number a thousand members. Then the reform and regeneration now so necessary will be easily effected. " An Act incorporating the Medical Society of Virginia. " Whereas it has been represented to the general assembly that sun- dry citizens hereinafter named, have for several years associated them- selves as a society, with a view to the advancement of medical know- ledge throughout the state of Virginia ; and that the accomplishment 114 MEDICAL SOCIETY OF VIRGINIA. thereof would be greatly facilitated, and their labors rendered more extensively useful, if they were vested with some of the attributes of a corporate body : " Be it therefore enacted by the general assembly, That William Foushee, Senior, George Cabell, George Watson, James Henderson, John Hays, Micajah Clark, Thomas Nelson, William A. Patteson, James Blair, William H. Hening, James Warrall, John Adams, Lewis W. Cham- berlayne, Robert H. Cabell, R. A. Carrington, John Dove, Branch T. Archer, William Tazewell, Nathaniel Nelson, Edward H. Carmichael, R. L. Bohannan, Philip Augustus Klipstine, William R. McCaw, as well as all others who may hereafter be admitted to membership with them, be a body corporate and politic by the name of the " Medical Society of Virginia;" that they shall be capable of suing and of being sued in any of the courts of this commonwealth ; that they shall have perpetual succession, and be authorized to use a common seal. " Be it further enacted, That it shall be lawful for the Medical society thus constituted to enact all such by-laws as they may deem neces- sary and proper for attaining the objects of their institution, and not contrary to the constitution or laws of the United States or of the com- monwealth of Virginia. " Be it further enacted, That it shall be lawful for said society to re- quire of persons admitted to membership therein, such admission fees, and annual contributions, as a legal quorum thereof may from time to time enact ; and if any member shall refuse or fail to pay such admis- sion fee or annual contribution, that the same shall be recoverable by the society, on motion with ten days' notice, before either of the superior or inferior courts of law held in the city of Richmond, or in any county, city or corporation whereof the member so refusing or failing to pay shall be an inhabitant. " Be it further enacted, That it shall be lawful for the said society to hold, under any title recognized by the laws of Virginia, such buildings as may be required for their immediate personal accommodation as a society, for lecturing rooms, for a dissecting room, and such other apartments as may be manifestly necessary or convenient for the pro- motion of medical knowledge. " Be it further enacted, That it shall be lawful for the said society to hold, under any title recognized by the laws of Virginia, whether coming to them by purchase, donation or otherwise, so much real pro- perty, exclusively of that mentioned in the fourth section of this act, whereof the clear income, on an average of ten years, shall not exceed two thousand dollars per annum. " Be it further enacted, That this act shall be at all times subject to be altered, amended or repealed, as the legislature of Virginia shall deem necessary and proper. " This act. shall be in force from the passing thereof." The above is a true copy of an act passed by the legislature of Virginia, the 2d January 1824. (Signed,) WM. MUNFORD, Clh H. of D. MEDICAL SOCIETY OF VIRGINIA. 115 Constitution of the Medical Society of Virginia. The objects contemplated by the Medical Society of Virginia, are — the collection, diffusion, interchange, preservation and general advancement of medical knowledge throughout the state. Its constitution embraces the qualifications, election and duties of its members, the election or appointment and duties of its officers and committees, and provides for its own amendment, whenever the ne- cessity and propriety of amending it shall be sufficiently obvious. The following are its provisions : ARTICLE I. Of Admission to Membership. Sec. 1. Eveiy candidate for membership must make application to the society by a written document, bearing his own signature. Such application is to be presented and seconded by members having a competent knowledge of the applicant, and can only be received at a stated meeting. Tne application shall lie over for one month, at least, for the consideration of the members, after which the candidate shall be ballotted for, and the approving votes of three-fourths of the mem- bers present shall be necessary to his admission. Sec. 2. In every city, town or county of the state, associate medi- cal societies may be formed, the members of which may become mem- bers of this society, upon the payment of the requisite initiation fee, provided their qualifications be such as are required in the following section. Sec. 3. But previously to a candidate being ballotted for, his qualifi- cations shall be duly ascertained, and shall be as follows : (a) The candidate shall have received, from some public school, society, college or university, legally authorized, a degree of bachelor or doctor of medicine or surgery, or diploma or other certificate, evidencing his capacity to practise medicine or surgery. (b) When such degree, certificate or diploma has not been ob- tained, the candidate shall furnish satisfactory evidence of having regularly attended, in some public school of medicine, lectures on anatomy, surgery, the theory and practice of me- dicine, materia medica and chemistry ; and of having passed in such academical attendance two full courses, and after- wards maintained a respectable standing as a practitioner for five years. (c) Or that he shall have attended one course of lectures in the before mentioned branches of medical science, and shall have afterwards practised with credit for eight years, submitted to a satisfactory examination before the society, presented a medical essay, and publicly defended it. Sec. 4. The person nominating a member shall be deemed respon- sible for all charges occurring against his nominee, for twelve months next ensuing the period of his election. 116 MEDICAL SOCIETY OF VIRGINIA. ARTICLE II. Of Honorary Members. Sec. 1. Honorary membership shall only be conferred on distin- guished medical characters residing beyond the limits of the common- wealth of Virginia, on presidents of the society who shall have dis- charged their official duties with fidelity and attention, and on mem- bers of five years standing, who shall have rendered eminent services to the society. Sec. 2. The election of honorary members can only be made at the annual meetings of the society, and not more than four shall be elected in any one year. Sec. 3. The election of honorary members shall be by ballot, and the concurring votes of four-fifths of all the members present shall be necessary to an election. Sec. 4. Honorary members shall be exempted from the payment of all pecuniary contributions to the society. ARTICLE III. Of the Duties of the Members. Sec. 1. All the members of this society (honorary members ex- cepted) shall, at the time of their admission, pay to the society a fee of one dollar, and shall also pay once a year, (to fall due on the 1st day of January, each year,) such contribution as the by-laws may from time to time prescribe. Sec. 2. A copy of any communication, after being read to the so- ciety, shall be delivered to the librarian. ARTICLE IV. Of Resignation of Membership. Any member wishing to withdraw from this society, shall be per- mitted to do so, on his written resignation, or the written request of the secretary of the associate society to which he belongs, after he shall have presented the treasurer's receipt for all moneys due. article v. Of Certificates of Membership. Every member shall be entitled to a certificate of his membership after he shall have complied with the requisitions of the 3d article. The form of such certificate to be prescribed by the by-laws. MEDICAL SOCIETY OF VIRGINIA. 117 ARTICLE VI. Of Forfeiture of Membership, or other Censure. Sec. 1. Any member who shall be guilty of gross misconduct, either as a member or citizen, or shall be palpably negligent of his duty, either as a member or officer, shall be liable to expulsion, or such other censure as the society may approve. Sec. 2. But no judgment of expulsion, suspension, or other censure, shall be passed against a member, till after at least one month's no- tice and a fair trial. And no member shall be expelled unless by the votes of three-fourths of the members present. And should such member come forward within the six months succeeding his expul- sion, and offer a sufficient explanation, he may be reinstated without expense, provided three-fourths of the members present agree thereto. ARTICLE VIL Of the Meetings of the Society. Sec. 1. The society shall be convened in the city of Richmond on the third Tuesday of every month. Sec. 2. Five ordinary members shall constitute a quorum for the transaction of all business to which the society is competent. Sec. 3. Special or intermediate meetings may be held by resolution of the society at its stated meetings, and at such other times as the president shall appoint, at the request of any three members. Sec. 4. The stated meeting in May shall be considered the annual meeting. ARTICLE VIII. Of the Election of Officers and Committees. Sec. 1. The officers of this society shall consist of a president, a senior and a junior vice-president, a recording and a corresponding secretary, a treasurer, a librarian, and a committee of publication, of three members ; all of whom shall be chosen by ballot at each annual meeting, and shall continue in office for twelve months, or until an- other election ; and the election shall have precedence of all other business at that meeting, after reading annual reports. Sec. 2. In conducting the annual election, should more than two members be ballotted for any office, the member having the smallest number of votes on the second or any subsequent ballot, shall not be voted for in such ballots as may follow. Sec. 3. In all cases of election, a majority of the suffrages of the members present shall be necessary to constitute an election, ARTICLE IX. Of the Duties of Officers and Committees. Sec. 1. It shall be the duty of the president to preside at all meetings of the society, to preserve order, and regulate the debates according 16 118 MEDICAL SOCIETY OF VIRGINIA. to the most approved rules of parliamentary proceeding : Provided, Any member shall have the right of appealing to the society from the president's decision on any question of order. The president shall appoint all special committees, unless otherwise ordered, except the committee of publication. Sec. 2. In the absence of the president, the vice-presidents, according to seniority, shall perform all the duties appertaining to the chair ; but if neither be present, the society shall elect a member to act as presi- dent for that meeting. Sec. 3. The recording secretary shall keep a correct list of all the members of the society, arranged in the order of their admission. He shall keep accurate minutes of all the proceedings of the society, in- cluding the names of members present, and from time to time tran- scribe them into the record book in a fair and legible hand. Such papers of the society as are not necessarily recorded, he shall preserve in distinct and regular files, holding them always accessible • for the inspection of the members. Whenever any special committee is appointed, the recording secre- tary shall furnish the chairman with a copy of the minute of appoint- ment, as well as any documents that may be essentially connected with the duties of the committee, or the chairman may require of him. Sec. 4. The corresponding secretary shall notify all members and offi- cers of their election ; he shall write and answer letters in behalf of the society; and, in general, manage their distant correspondence, as particular exigencies or the resolutions of the society may require. He shall read to the society all communications and answers which he may have received or made during each preceding recess, and then deliver them to the recording secretary or the librarian, according to their several characters. Sec. 5. The treasurer shall receive all moneys arising from the ad- mission and contribution of members, and shall pay the same agree- ably to the orders of the society, certified by the member presiding. He shall keep regular accounts with the society, and between the society and the members thereof; and immediately preceding each annual election, or oftener if required by the society, shall render de- tailed statements of the business of his department, and shall deliver up to his successor the books, papers, money, or other property of the society remaining in his hands. For the faithful performance of his duties, the treasurer, before en- tering thereon, shall execute bond to the president and vice-presidents for double the amount with which they, or any two of them, shall judge he may probably become entrusted during his continuance in office. ^ Sec. 6. The librarian shall have under his custody, and it shall be his duty to take special care of, all the books, essays, and whatever may constitute any part of the literary or scientific stock of the society. The books he shall give out for the perusal of the members under such regulations as the by-laws may direct ; but no manuscript shall be carried out of the library without a special order from the society, except by the members of the committee of publication. MEDICAL SOCIETY OF VIRGINIA. 119 Sec. 7. It shall be the duty of the committee of publication to select from the essays of the members, and other communications made to the society, such as they may think worthy of being published. They shall, whenever they deem it expedient, report to the society that they have selected a sufficient number for publication ; and when the society deem it proper, the committee shall publish their selection under the title of the " Transactions of the Medical Society of Virginia." After the publication of each number or volume of the Transactions, the committee shall return to the librarian all papers belonging to the society. ARTICLE X. Of Amending the Constitution. Every proposition for amending this constitution shall, on being se- conded, be handed up in writing to the chair. It shall then be audi- bly read by the recording secretary, after which the society shall de- cide whether it pass to a second reading. If they resolve in the affir- mative, it shall be placed on file to be read at the next regular meet- ing, when the question shall be taken on its third reading, and if so determined, the proposition shall again be read and finally decided at the third meeting ; but shall not even then be adopted, unless with the concurrence of three-fourths of the members present. By-Laws of the Medical Society of Virginia. Section 1. Two days previous to each stated meeting, the record- ing secretary shall give notice thereof in writing to each member re- siding in Richmond and Manchester, and six weeks previous to the annual meeting, he shall give notice thereof through the public prints. Sec. 6. When members resident in the country present communi- cations to the society, they shall be allowed precedence of members in town in the reading thereof, though junior in the time of admission to membership; and all voluntary contributors of communications shall be entitled to the same privilege. Sec. 10. The annual contribution of each member residing in Rich- mond or Manchester shall be fixed annually. Sec. 11. The associate societies of each city, town or county, shall, at the annual meeting of the society, report to the secretary the num- ber and names of their members, and any other matter they may deem of importance to the interests of the society. Sec. 12. Each member of the society shall have the privilege of inviting medical gentlemen and students of medicine to attend the mee lings of the society. 120 MEDICAL SOCIETY OF VIRGINIA. Proceedings of the January (21st) Meeting. A very large number of members and visitors were in attendance. After the usual business, several gentlemen were balloted for and elected members of the society. Dr. F. H. Deane then operjedthe subject of the evening, by making some remarks on " the use of calomel in the treatment of scarlet fever." Dr. Bolton here interrupted the discussion by stating that he wished to exhibit to the society a chemical experiment for testing the purity of cod-liver oil.* If not performed at this time it must be omitted altogether. The attention of Messrs. Adie & Gray of this city had been called by the president of the society to an article by Levick, in the American Journal of Medical Sciences for the present month. It is stated by this writer, on the authority of one who has been extensively engaged in the preparation and sale of cod-liver oil during thirty years, that the best method of testing the oil, is as fol- lows : " Take a small vial half full of the oil, add say one-eighth part of nitric acid, shake it well together ; if it turns a handsome orange color and remains so for thirty minutes or more, it is a test for pure oil ; but if it turns quite dark it may be suspected that other oils are mixed with it." An animated and interesting discussion then ensued, in which there were many participants, and which lasted until a late hour. It should be reported if space permitted, and will most probably be given in our next. Typhoid fever was then made the subject for the February meeting. A committee of three was then appointed to report a memorial to the city council for the establishment of a Dispensary. A resolution appointing a committee to report the experience of the profession in the city, in regard to ancesthesia in medical, surgical and obstetric practice, was adopted. Drs. James Bolton, C. Bell Gibson, John A. Cunningham and W. W. Parker wTere appointed said com- mittee. (We are requested to ask that gentlemen in this city and else- where, having communications to make on the subject, will please do so as early as possible to Dr. Bolton, chairman of the committee.) The president was empowered by resolution to appoint the number of delegates to wThich the society is entitled to represent it in the Ame- rican Medical Association, which is to assemble in Charleston, South Carolina, in May next — and that he himself be included. These de- legates will be announced in due time. * Samples from several different manufacturers were placed in a conspicuous position, and the test was applied. The result was, that but one responded to it. This was procured from a person in Philadelphia by the name of Shaw, who is the agent of a house, whose name was not learned. Some of the clear oil poured from the top of a bottle of Rushton, Clark & Co's. turned brown. On shaking up the same bottle the next day and testing again, a nearly black color was produced. Simes & Baker's turned to a salmon color. Errata in January Number. — Page 5, 13th line from bottom, last word, read "presently,"' for frequently. Page 30, 7th line from top, read "esodic," instead of exodic. MEDICAL INTELLIGENCE. 121 To the Medical Profession. — The undersigned, chairman of the stand- ing committee on practical medicine, appointed by the American Medical Association, May 1850, respectfully solicits the co-operation of members of the medical profession in furnishing materials for the annual report in May 1851. The duty of this committee, as de- fined by the constitution of the association, is to "prepare an annual report on the more important improvements effected in this country in the management of individual diseases; and on the progress of epi- demics ; referring, as occasion requires, to medical topography and to the character of prevailing diseases in special localities, or in the United States generally, during the term of their service." In order to fulfil the objects thus expressed, the requisite data must be supplied by medical practitioners in different sections of the Union. This is more particularly true with reference to the "progress of epidemics" and "the character of prevailing diseases in special localities." Com- munications, therefore, are particularly desired from persons residing in places in which epidemics have prevailed, or in which prevailing diseases have been marked by special characters during the present year. Epidemic cholera and dysentery are known to have prevailed more or less in different parts of the country during the past summer. Facts bearing upon the features peculiar to the present season, the production, diffusion, mortality, treatment, &c, of these diseases, will be acceptable. It is requested that communications upon these or any of the subjects coming under the cognizance of the committee, be transmitted to the undersigned by the 1st of March 1851. All contributions with which the committee may be favored will receive due attention and acknowledgment. AUSTIN FLINT. Buffalo, N. Y., Nov. 1850. Surgical Report for the American Medical Association. — The com- mittee is invited to meet in the Charleston hotel, South Carolina, the evening of the first Tuesday in May next. All professional brethren who have surgical facts connected with the improvement of this branch of the profession during the year, will please address them to the chairman of the committee by the 1st of April, at Augusta, Georgia. As all cannot be reached by a circular, it is hoped no one will wait for a more direct application than this general invitation. PAUL F. EVE, M. D., Prof, of Surgery in the Louisville University, and Chairman of the Committee on Surgery of the Am. Med. Association. Louisville, Ky., Dec. 1850. American Medical Association. — The committee of arrangements re- quest all societies and other institutions authorized to send delegates, to forward a correct list of those selected to attend the next annual meeting, to the secretary, Dr. H. W. De Saussure, at Charleston, S. C, on or before the 1st day of April. In consequence of the resignation of Dr. Stille, one of the secretaries, from ill health, all communications intended for the next meeting of the 122 ADVERTISEMENTS. association must be addressed to the remaining secretary, Dr. H. W. De Saussure, Charleston, S. C. The fourth annual meeting of the American Medical Association will be held at Charleston, S. C, on the 2d Tuesday of May next. 139 MAIN STREET, RICHMOND, VA. Wtal txtm5ivt[^ in BOOKS, STATIONERY, AND P1AH9 MBVUh In the department of MEDICAL LITERATURE, they devote particular attention in keeping up a full supply of the Standard Works, as well as the late publications, and offer them for sale as low as they can be had in any regular establishment in the United States. They furnish all the Medical Periodicals. I3P3 English, French and German Books imported to order, with care and despatch. MBBIB * BROTHER, (LATE DRINKER & MORRIS,) Wholesale Booksellers, Stationers, Publishers, and Dealers in Piano Fortes, Music, Musical Merchandise, Fancy Goods, &c, &c. 97 MAIN STREET, RICHMOND, VA,, Are constantly supplied with the most important publications in every department of literature, the arts and sciences. Orders from private individuals, schools, colleges, academies, semi- naries of learning, or other public institutions for Books, Stationery, Piano Fortes, Sfc, 8fc, will be furnished on the most favorable terms, and with the greatest despatch. Foreign books imported to order. Morris & Brother are the sole agents for the sale of Worcester's unrivalled Instruments, and in evidence of their superiority beg to sub- mit to a discriminating public the following testimonial : Improvement in Pianos.— New York is fully entitled to the credit of having effected the greatest real improvements in the construction of that noblest of all instruments, the Piano. Some others may have added to the sweetness of certain parts of their instruments at ihe cost of the power and brilliancy of the whole; while others again have lavished money upon the fantistic decorations of the frames; but to our fellow-citizen Worcester, whose Pianos have latterly made way so rapidly into public favor, belongs the merit of increasing at the same time the power, quality and endurance of tone, and without a corresponding exaggeration of price. — New York Mirror. ADVERTISEMENTS. 123 DRUGGISTS, No. 92, corner of Main and 14th Streets, RICHMOND, VA. KEEP CONSTANTLY ON HAND A LARGE AND GENERAL ASSORTMENT OF FRESH AND RELIABLE DRUGS, MEDICmSS; French, English, Crermai and American Chemicals; Surgical Instruments, Physicians' Saddle Bags; PAINTERS' COLORS, OILS, DYE-STUFFS, WINDOW GLASS, ETC. We are careful in the selection of articles, and endeavor to offer none but those of reli- able quality and known purity. ISF0 Particular attention is given to the preparation and procuring of ALL NEW PHARMACEUTICAL PREPARATIONS and CHEMICALS, which are added as they are introduced so as to render our stock at all times complete and desirable. Our facilities enable us to offer to purchasers such inducements as will give satisfaction. USF* Orders promptly and carefully attended to. ROBERT M'NAMEE, MAKER OF MAIN STREET, opposite American Hotel, Asks the attention of Physicians and Dentists to his stock, which will be found to comprise all kinds of Dental and Surgical Instruments, Trusses, Cutlery, &c. He likewise makes to order and repairs all descriptions of Instruments. Thankful for the liberal patronage he has already received, he trusts to be able to merit a continuance of it, by increased business facilities, and a determination to give entire satisfaction to his patrons. AMU ft ffi&AW9 APOTHECARIES ANI> DRUGGISTS, Richmond, Va., (SUCCESSORS TO ALEXANDER DUVAL,) Dealers in all kinds of Medicinal Preparations, English, French, German and American Chemicals of the most approved makers. Also, the well known Pharmaceutical Prepara- tions of Herring & Brothers of London, Howard & Kent, Morson and others. Surgical and Dentists' Instruments, Paints, Oils, Dyes, Window Glass, Perfumery, Brushes, &c, &c. Physicians and o.thers may rest assured that their orders will meet with prompt attention, and be supplied with articles of unquestionable quality. 124 ADVERTISEMENTS. INFIRMARY This institution, under the management of the Faculty of the Rich- mond Medical College, is open for the reception of patients through- out the year, at the following charges : Colored Patients, - $ 4 per week. White Patients, - 5 For a Private Room, the charge is 7 These charges cover all expenses for diet, nuising, medicines, me- dical attendance and surgical operations. The Infirmar}' was established thirteen years ago, and the success which has attended it, the benefits it has conferred on the sick, and the trifling expense at which these benefits are secured, commend it to the favorable attention of the public. The fees for the first week are required to be paid in advance. Gentle- men sending patients from a distance will please give a city reference. Attending Physicians. Prof. TUCKER, BOHANNAN and CHAMBERLAYNE. Attending Surgeons. Professors GIBSON and JOHNSON. S. MAUPIN, M. D., Tres. of the Infirmary. PRINTING AND BOOK BINDING. GF° We take this occasion to inform our friends and the public, that we have, at great expense and much labor, laid in the fullest supply of materials for executing all kinds of PRINTING & BOOK BINDING Promptly, and on reasonable and satisfactory terms. The new " Code of Virginia" and the " Stethoscope" present a fair specimen of the typographical capacity of our office — and we are prepared to execute all kinds of work in the same style. Of every description neatly executed, in various colors, (Gold, Bronze, 8?c. Sfc.) For Lawyers, Clerks of Courts, Sheriffs and Constables, printed to order. For Merchants, Clerks of Courts, &c, made to order, and ruled to any pattern. Old Books re-bound. PRINTING INK. News, Book and Job Ink of different colors and the finest quality, always kept on hand. Address RITCHIES & DUNNAVANT, Richmond, Va. THE AND No. 3, RICHMOND, MARCH 1851. [Vol. L Abstract of an Essay on Typhoid Fever. BY JOHN P. LITTLE, M. D., OF RICHMOND CITY. [Read before the Medical Society of Virginia February 18, 1851.] I will not speak of typhoid fever in the present paper as occurring in Europe, or as it is found in some parts of our own country, but will confine myself to the disease as I have met with it in practice, or ac- quired knowledge of it by conversation and correspondence. It is known to have existed in some parts of Virginia (in the Valley about Staunton for instance) for fifty years past; in most parts of our state, however, it is of recent origin. In the Valley it is the fever of the couniry, never occurring epidemically, generally mild in character and tedious in duration, requiring the expectant treatment, and when fatal, generally so from cerebral complications. Dr. Waddell of Staunton is my authority for this statement. In Loudoun and Fauquier it has existed some twenty years, having crossed the Ridge in 1830, and has been spreading over those counties from that mountain range ever since in an easterly course. It did not there prevail epidemically until the summer of 1849. It made its appearance in Danville and the region around, about the year 1845, and the next year epidemic typhoid fever shewed itself in Nelson, Albemarle and Madison. In 1847 and '48 it gradually overspread those counties, and extended into and over the adjoining ones of Culpeper, Orange, &c, and in 1S49 prevailed as an epidemic in Fauquier and other counties neighboring. The dis- ease has evidently pursued a northeasterly course, and has rather spread during the summer season, as if it was borne on the south or southwestern winds that prevail during that season. It was preceded during the years 1845 and '46, over a large part of these counties, by abundant remittent and intermittent fever. Regions of the upper country, never invaded by those fevers, afforded during the summer of those years no other affections, and in many parts of what were sup- posed the non-miasmatic regions scarcely a family escaped the visita- tion of one form or other of these diseases. Many of these cases 17 122 LITTLE ON TYPHOID FEVER. were of so debilitating a character, of so long continuance and liability to relapse, that they deserved the name of typhoidal cases. This epi- demic of a remittent and intermittent class of fevers, with tendency to a typhoidal character, served as a fit introductory to the more formi- dable disease. Great mortality accompanied the first invasion of this epidemic form of Typhoid fever, especially in the counties of Albemarle and Madi- son. Whole families were prostrated, both white and black, and in some households, where forty or fifty were under the disease, more than half died. An active treatment from mistaken opinion of the disease, the influence of fear, and the frequent neglect of the sick, owing to the large number affected, leaving often a very few who were well to attend a large number of sick, were causes of this result. In the majority of cases treated in Madison county, from one-third to one-sixth died before the alarm subsided under a more judicious plan of treatment. The question of contagion was often raised, and cer- tainly there appeared some ground for the belief, as the disease espe- cially invaded those who attended the sick, and was more apt to oc- cur among the night-watchers. So much for the history of the dis- ease. The term typhoid fever has been so constantly applied to every form of depression in fever, and the typhoid state is so often spoken of, that it is difficult to get a clear idea of the term. Whether drawn from the Greek word, which means debility, or from the Egyptian word, which means the devil, it is alike applicable to the appearance of the patient, and the provoking and often fatal character of the disease. I consider it a true dothinenterite, the primary s}Tmptom and essence of the disease consisting in a peculiar inflammation of the mucus membrane (with the glands lying in it) of the small intestine, this inflammation extending often into the large intestine ; and these glands thus inflamed tending to take an ulcerative action. Accompany- ing this we have general irritation of the system, shewing itself in fever, &c, and the local irritation producing diarrhoea, and in some cases haemorrhage early or late occurring. Other organs of the body often become affected during the progress of the disease, and death frequently results from these complications. Its cause is unknown ; and the duration of the disease, if the patient die not, is generally from four to eight weeks. In considering the pathology of this affection, we must consider the position of the disease and the disorders likely to arise from such an affection so situated. It is then a disease affecting a sheet of mucus membrane, which, if spread out, would cover a space of 1440 square inches for the small intestine, and 500 more for the large intestine, equal to about ten square feet. The whole of this is not equally affected, yet the function of the whole is either destined or impaired, and parts of it so much affected as to ulcerate. This membrane too is the organ through which the chyle, formed from the food, is carried into the general system, and by its action the body is nourished. It lies too in and near the extensive ganglionic system of nerves, which, besides anastomosing with the cerebral and spinal systems, supply the LITTLE ON TYPHOID FEVER. 123 viscera of the abdomen in their several functions, send their ramifica- tions to the heart and lungs, and accompany with their ganglions and fibrilae the minutest arterial branches. It is a membrane also which has for its base and substance an extensive plexus of veins, through which all the blood in the body rapidly passes, and by whose diseased state the character of the vital fluid must be essentially changed. In these modes then the disease is dangerous ; from the direct action of the inflammation, from the impaired nutrition, from the change in the blood, and from the extensive and varied nervous sympathies. Ulce- ration in such an organ is dangerous in itself, and more dangerous from the fact that the system may be re-inoculated from this source. Symptoms. — In all cases the approach of the disease was gradual ; there was general uneasiness felt, and headach was complained of, with furred tongue, a quickened pulse, disturbed sleep, chilliness and tendency to diarrhoea. With some, the disease went no farther. I have known patients with all these symptoms to continue on their feet and attend to business. I had the disease in this form myself and still attended my cases. These symptoms continue and increase in severity ; a chill comes on often ; the patient is compelled to lie down from weakness ; fever, with heat of skin and a pulse varying from SO to 140, according to the severity of the case, appears ; discharges of a yellowish color and watery consistence, or turbid and dark brown, or black like tar and very offensive, take place with more or less frequency, according to the severity of the disease. Occasionally discharges of blood take place, mingled with the matters evacuated ; epistaxis occurred in al- most every case, and may be indeed considered almost a symptom of the disease ; these haemorrhages occurred generally as early as the second week. The appearance of the tongue varied ; in the most rapidly fatal cases there was scarcely any abnormal appearance ; ge- nerally it is coated with a white tenacious fur, becoming yellow and black, and the tongue itself became dry as the disease advanced ; its substance also is fissured, and sordes collects on the lips and teeth. The gurgling sound, heard on pressing over the right iliac region, was in no case absent after the diarrhoea had set in ; and tympanites often occurred in the latter stages of the disease. Abdominal pain was often complained of in the early part of the disease, more especially if purgatives had been used improperly. Affections of the nervous system began early and continued ; they were shewn in the headach, debility, chilliness and muscular tremor, as seen in protruding the tongue and in moving the body. The headach soon ceasing, either from epistaxis or from other cause, the patient generally lies painless, answering that he feels quite well ; the vacant look, the deafness and other disturbance of the senses occurring early in the case, restless slumber and unconsciousness of having slept at all, wandering of in- tellect on waking from sleep, and muttering delirium when awake — all indicate the decided impairment of the nervous system. To these, in grave coses, are added, dimness of vision and a tendency to sub- sultus tendinum. During the progress of the case, emaciation steadily advances, and in exact proportion to the severity of the case. In the 124 LITTLE ON TYPHOID FEVER. latter stages, sometimes sudden hasmorrhage from the bowels came on, or violent pain and acute peritoneal inflammation carried off the already worn out patient. In the one case, a vessel had been eaten into by ulceration ; and in the other, perforation of the intestine had occurred from the same cause. Again — sometimes the cervical glands would become inflamed and swollen largely, apparently inoculated by the depraved condition of the blood and the presence of ulceration in the abdomen. I never knew this to occur until I felt satisfied, from the condition of the patient and the duration of the disease, that the glands of Peyer were in an ulcerated condition. This class of cases generally died ; the patients not being able, in so late a period of the disease, to bear up under the new inflammation, or death being assisted by strangulation induced by the swelling. Hysterical symptoms I have always looked upon with alarm, and esteemed them indications of new danger in an already impaired and excited condition of the nervous system. Especially is this the case, if they occur at the men- strual period. In fact, as the disease lasts for a longer time than in- tervenes between two menstrual periods, the occurrence of this dis- charge and the consequent disturbance of system should be looked for with some degree of dread. The amount discharged itself cannot well be lost by a very feeble patient — it is often profuse ; and when with this much excitement and consequent languor ensues, or if hyste- ria make its appearance, a mild case of disease may become severe, and a severe case become fatal. I regard the menstrual flow as an alarming s}'mptom in the latter stages of typhoid fever. Of prognosis in this disease much need not be said. Some cases seemed marked out for death ; these died early in spite of every effort. In some the disease was severe from its complications, and these differed in different parts of the country and in different seasons of the year. In the winter the head was chiefly affected, and pneu- monia was the most frequent fatal complication during other seasons. This came on insidiously, and could not be detected without careful examination of the chest. The aged, the feeble and the very young were less able to stand the length of the disease, and often sunk under the necessary confinement of it, instead of its violence. Our opinion in a case of typhoid fever may be regulated by ob- serving the character and abundance of the diarrhoea, the frequency of the pulse and the progress of the emaciation ; if these go on rapidly there is danger, and vice versa. Treatment. — The first thing to be done in treating this disease is, to render the patient comfortable in the bed on which he is to lie so long, and then to get him a good nurse. In no disease has the " nimia cura mcdend'C caused more harm and produced more deaths than in this one. Good nursing, without a physician, will be twice as valuable as the most skilful physician with bad nurses. The indications for treatment are, to guard the important organs and to husband the powers of nature until the patient gets well. Many patients die of starvation in this disease. It is forgotten that no man can lie in a sick bed for four or five weeks, with a disease of LITTLE ON TYPHOID FEVER. 125 the organ of nutrition itself, and not require sufficient food. The irri- tation of S}Tstem natural to the disease is increased by the want of food, and the patient wastes for lack of nutriment. Light and whole- some food should be given as regularly, and more frequently because in smaller quantities, as in health. Mild laxatives, if used early in the case, render the progress of the disease milder. They must be used early, however; the mildest enema is alone needed during the course of the disease. Rest, in the horizontal position, is itself a valu- able remedy, and warm fomentations to the abdomen have a salutary effect and add to the comfort of the patient. Venesection, although advised by some writers, and by some physicians with whom I have conversed, has never been required in any case that I have seen ; nor is it recommended b}^ those on whose judgment I rely. I have never known it to be used in this epidemic form of the disease, even when apparently required, without being followed by death. Local bleeding over the abdomen by cups and leeches, followed by decided counter-irritation, was indicated, and had good effect, if early applied, in checking the diarrhoea and mitigating the severity of the case. In some cases it could not be borne ; the patient could not afford to lose blood in any manner. Then, dry cupping, and stimulant applications well rubbed in, or a large mustard plaster over the whole abdomen, would serve. My custom was, during the severity of the case, to have dry cups applied daily, (teaching the nurse to use large tum- blers,) then to rub in spirits of turpentine. This last was often com- bined with diluted nitric acid and opium. It acted as a counter-irritant, and part of it also was probably absorbed and possessed some astrin- gent effect on the diarrhoea. Dr. Wood's suggestion as to the use of turpentine in some cases was found useful ; from trial, we believe that it can be used as a valuable adjunct to treatment from the be- ginning. Contrary to the opinion advanced by Bartlett, and sustained by many authorities, blisters were found very useful in very many cases. They were not used very early — not until there was some abatement of fever ; before this they added to the excitement of the patient. Yet, when this blistering point was reached, their use was decidedly beneficial, and they could be used repeatedly over different parts of the abdomen. Diuretics should be used, and the patient often directed to pass his urine, otherwise he will forget it, and the accumulation produce injury. Demulcent drinks, as infusion of slippery elm, with sp. nitre dulc, were used ; ice to the head, in cases of pain or extreme heat, and small pellets held in the mouth to quench thirst, were adjuvants to treatment, and made more comfort- able the patient. Astringents were of little service ; they were tried, of all kinds, and in the severer cases nit. argent, or acet. plumb, did not restrain the diarrhoea. Kino, either alone or combined with opium, was decidedly the most useful of them all, and could be used from the bemnnino; of the case. One of the chief indications in treatment is to give your patient a good night's rest; and to do this give him sufficient opium. This remedy is well borne, in typhoid fever, in large doses, while the small ones produce excitement and delirium. It is necessary that the pa- 126 LITTLE ON TYPHOID FEVER. tient sleep ; and to do this give him from a quarter of a grain of acet. morph. to a grain, or equivalent quantity of opium. He must sleep ; and I have given it in the delirium, and in spite of the excite- ment, in large quantities, with the effect of quieting excitement and of saving life. Practitioners are too much afraid of the use of large opiates in fever ; they use it with caution where it should be pushed boldly. Our most important remedies, however, were mercury and quinine; they were the right and left hands of practice in this disease. Calo- mel, or rather blue mass, with Dover's powder and kino, if much di- arrhoea existed, was given in the severer cases, usually in these pro- portions and thrice a day. 3--. blue mass iij grains, Dover's powder vi or viij, and kino v to xx grs. This was kept up for some time ; leaving out the Dover's powder if much excitement prevailed. As soon as this excitement was found to be abating, quinine was used, and increased in quantity as the patient was found to bear its use. On this practice we were much disposed to rely; mercury as an al- terative, quinine as a tonic, and opium sufficient to compel sleep. In swelling of the cervical glands a blister early applied was found most serviceable in preventing the swelling from increasing; and sti- mulant applications, with support to the general system during the progress of the affection, were demanded. In one case only did any good result from treatment when subsul- tus tendinum had set in ; it came on suddenly in a patient much pros- trated, and an enema of soup with half an ounce of brandy and 20 grs. of camphor was administered every half hour until the patient rallied and the affection ceased. This patient lived for several days ; began to mend, and died suddenly under a large haemorrhage from the bowels. For hysterical symptoms the assafoetida enema was most serviceable. With regard to the haemorrhages that occur, I regard two of them as salutary. I allude to the epistaxis, which commonly occurs and relieves the head very much, and to that haemorrhage from the bowels which occurs early in the disease in some cases, and which appears to make the case milder. This appears to come, as the epistaxis does, from the congested state of the mucous membrane, and is an effort of nature to relieve itself; it comes from the surface, and differs from the haemor- rhage so often fatal in the latter stages of the disease. The one is purer and brighter blood, from a vessel opened by ulceration ; the other comes from the surface of the membrane, and is mixed more or less with fecal matter. I am inclined to think that it occurs more often than is imagined, and being mixed up with the discharges, is unnoticed by the attendants. In some cases, from the beginning al- most, a gently stimulant plan of treatment must be pursued, in addi- tion to the use of the quinine ; and during the latter stage of the dis- ease, while the system is depressed by its duration, and the powers of life are scarcely able to support the ulcerative process, stimulants of a decided character must be used according to the patient's strength or weakness. The chief advantage of the use of mercury appears to be in preventing complications from occurring; patients rarely be- LITTLE ON TYPHOID FEVER. 127 come affected by it, as it seems to pass off in the discharges. In many- cases where I saw the gums slightly touched, there were none of the frequent complications, and the patient made a more rapid recovery. All the physicians who treated this form of the disease agree in the use of mercury as an alterative, and quinine as a tonic. It seems to have arisen with different men in different parts of the country ; they were forced into it by the nature of the disease and the insufficiency of other treatment ; and it therefore possesses strong claims to our belief, as the concurrent testimony of many observing physicians. I am disposed to believe that there is antagonism between this dis- ease and the usual bilious remittent fever of the summer. They do not exist in the same place during the same season ; one displaces the other; and even in the typhoidal cases of bilious fever, in which the diseases appear mingled, the second epidemic or invasion of fever is more likely to be typhoid than bilious fever. The one surrendering its sceptre of terror to a rival still more terrible and dangerous. The one is a disease of the upper country, the other of the lower, and they mark the peculiar character of their respective districts. I would thus account for the singular fact, often observed in the upper country, that those who come there to escape bilious fevers are liable to se- verer forms of fever than those of the district they left, or of that to which they have come. They bring the seeds of one disease with them, and engraft on it the influences of another. No class of fevers are more difficult to treat than this one ; they require care, combina- tion of treatment, and last for a long time, exhausting the patient by the violence of the disease, and wearing him out by its length. The typhoid seems destined to supplant our other forms of fever ; as in the last year or twro it has entered the lower country of Virginia, and is there imparting its character to the diseases. As, however, it has always shewn itself in a milder form, after having prevailed epidemi- cally and with violence, it is probable that, when it becomes the pre- vailing fever of our part of the state, its violence will be so far abated that a mild expectant course of treatment will be all that is necessary in its cure. With regard to prophylaxis, I have observed that in large gangs of negroes, where saccharine substances, molasses especially, were used as food, the disease did not prevail. I saw one case, in a cluster of negro houses, where over sixty slaves lived and slept ; in a house too where some dozen of them made their abode ; the disease did not spread, although it spread through that neighborhood. Again, I knew the disease to exist in severe forms in establishments around this one, without invading it ; there was no difference in the food served out, save of the kind mentioned. On making inquiry, I learn that on se- veral plantations in the upper counties on James river, a similar fact has been observed. I do not assert that molasses as food is a prophylactic in this dis- ease ; I give the fact, observed and corroborated, for what it is worth. One other suggestion has struck me in writing ; as typhoid fever is a disease of nutrition, and as emaciation goes on rapidly in it, would it not be of service to the p:itient to use cod liver oil largely, as diet in this tedious and wasting disease? 128 DEANE ON SCARLET FEVER. I have thus put together, in as compact a manner as possible, some memoranda of typhoid fever, preferring conciseness to completeness of description, and thus leaving the subject open for discussion by the society. Remarks of Dr. F. 3EL Deane on Scarlatina and Measles, In presenting the subject for discussion at the January Meeting of the Medical Society. Dr. Deane said he intended to make only a few remarks, and he would endeavor to avoid all allusion to such features in both diseases, in relation to which there existed unanimity of opinion among medical men — to discuss such points would be to occupy the attention of the society most unproritably. He would not argue the point of the con- tagiousness of these diseases, but would merely express the belief that both of them are contagious — scarlet fever less so than measles. In relation to the pathology of scarlet fever, he thought the theory which most nearly approximated probability, was the one which as- cribed it to some morbific cause in the air, most probably an animal poison taken into the blood, poisoning it, and that soon the nervous system became involved, and this disorder of the nervous S3Tstem was soon followed by that condition of things usually termed congestion — this, at any rate, appeared to be the case, if we selected the more ma- lignant forms in forming our opinions. However, it was his wish to avoid the pathology of the subject as far as possible. His object was to arrive at something useful in the way of treatment — he wished to contrast his own experience in the management of these diseases with that of others who were present — not that he was satisfied with his treatment, but still it was the best with which he was acquainted. He should select certain modifications or complications occurring fre- quently in both diseases, and which placed the patient in circum- stances of the greatest peril, and which involved points of treatment of the greatest difficulty and embarrassment. But before considering these complications he wished to premise, for fear of being classed with those who were charged with active interference in the treatment of these diseases, that oftener than otherwise he suffered both of them to pass through their different stages without administering a single remedial agent. It was certainty true that the simplest form of scar- let fever did not require any thing deserving the name of treatment, and the same thing was true as regards the second form in many in- stances, and it was even to a great extent true in the malignant form. The greatest discretion was necessary in his opinion before we ven- tured even to administer the simplest aperient or any other agent. Oftentimes a fearful struggle was seen to exist between the disease and the resources of nature, and under such circumstances one could not be too cautious how he interfered. And notwithstanding all this, he feared there were some so much influenced by the fact that both diseases run a prescribed course, as to induce them to push their views DEANE ON SCARLET FEVER. 129 of expectancy rather too far. He wished to be unders'ood as being one of those who would not be deterred in endeavoring to relieve a perilous condition of things, because his patient had scarlet fever or measles, by all the resources known to the healing art. He admitted that his treatment would be somewhat modified. What he objected to was, the ultraism which said, you should not bleed, or you should not stimulate. After these preliminary remarks, he proceeded to the consideration of the complications in these diseases, to which allusion had been made. We are often summoned to a child fifteen or twenty months old, and find him with a quick, feeble pulse, cool surface, pallid face, with frequent vomiting and diarrhoea. The whole appearance of the child indicates more constitutional disturbance than cholera morbus, occa- sioned by ordinary causes, would produce. If you are told the child has been guilty of no imprudence in diet, and if the season of the year is unfriendly to the appearance of bowel affections, and especially if scarlet fever is prevailing, you may naturally conclude your patient is suffering from it. Such a condition of things I regard as being replete with danger — the vomiting and purging will become more and more frequent, the passages will soon be colorless, and unless this condition is relieved, your patient soon has a convulsion, and probably dies in a few hours. Now, I regard this condition as one of congestion ; the indication is to develop reaction, and in this way relieve the over- powered nervous system and the suffering viscera. I would seek to accomplish this by the warm bath, the frequent application of sina- pisms, the use of warm foot-baths, with mustard and salt in them. If the system was greatly depressed, I would use ammonia or camphor, and at the same time I should not hesitate to use calomel every hour or two in one or two grain doses, until the vomiting and purging di- minished in frequency, or else the passages improved in appearance; and generally ten or twelve grains will accomplish this. I have often seen this treatment fail, to be sure; I do not think, however, I ever knew it to produce mischief. Often, by arresting the vomiting and purging, I have seen reaction take place and patients recover that otherwise would have perished. 2dly. We are often called to a patient and find he has vomiting and purging, and we discover some appearance of eruption, and there re- mains considerable heat of skin; but every time the patient vomits or has an evacuation from the bowels the eruption greatly diminishes or else disappears altogether. This state of things is often seen in both scarlet fever and measles. Unless you can develop the eruption more fully and increase the temperature of the skin, these cases will soon become as unfavorable as the one we have just instanced, and the termination will be as unfortunate. I would endeavor to relieve it by the means I have already pointed out, modified, it is true, by the circumstance that the danger is less intense, therefore not requiring the same energy of treatment. Again, we may find the patient with pun- gent heat of skin in scarlet fever, with a high degree of arterial excite- ment, with cerebral disturbance enough to make you fear great 130 DEANE ON SCARLET FEVER. hazard from this quarter, besides the patient to some extent has vomit- ing and purging, and whilst the evacuations from the bowels are not watery, they yet appear vitiated, and are wanting in bile. At this time there may scarcely be any evidence of an eruption, This is a case where you may soon expect death to ensue from injury to the brain. I would treat such a case by the cautious withdrawal of blood either generally or topically. I would not bleed the patient from any hope of cutting short the disease, but merely to protect a vital organ to enable the disease to pass through its stages ; and with a view of relieving this congestion of the brain, I would use calomel until I dis- covered biliary secretion in the passages. I do not wish to be under- stood as recommending such practice as this unless the symptoms and the whole appearance of the patient produced an impression on my mind that the greatest danger to life was to be apprehended. Under such circumstances I expect no aid from nature — I have seen it fail too frequently to commend the practice to use. The complications which 1 have alluded to occur, as I have already said, anterior to the time of the full development of the eruption. I will now mention one or two, often seen at or after the period of des- quamation. At this period, the febrile symptoms, after either having greatly diminished or disappeared altogether for a day or two, recur perhaps with increased intensity. The tongue, from having been clean and red, becomes indicative of less gastritis, and perhaps is thickly coated. The external glands of the neck became greatly en- larged, the tonsils are also greatly swoln, and the ulceration of the throat appears worse. A calomel purge under these circumstances, I think, often mitigates this congested and inflammatory state of things about the throat, and simplifies the subsequent treatment. If the state of the circulation seems to justify it, bleeding generally or topically ought to be practised, merely with a view of moderating the symptoms. It frequently happens ten or fifteen days after a child has recovered from an attack of scarlet fever, symptoms of dropsy manifest them- selves. The child appears bloodless ; the tongue looks bloodless ; it presents no evidence of the acute gastritis which existed during the eruptive period and the one of desquamation. A tendency to consti- pation is seen in the place of the diarrhoea of the early stages. These dropsical appearances may be accompanied with or without fever. I have observed at this time that no purgative seems to distress the pa- tient or to be followed by hypercatharsis, whereas at an early period of the disease a small dose of oil would have produced the greatest dis- tress. In the commencement of these dropsical appearances I am in the habit of prescribing calomel freely, followed by some aperient. The condition of the patient appears to be one of torpidity, and I have found it serviceable for the first three or four days to purge actively with calomel — if relief is not obtained, I am sure at least of some mitigation in the symptoms, and afterwards rely upon diuretics or to- nics, according to the indications. In regard to measles, we often find the same condition of s}^stem antecedent to the eruption as that which exists in scarlatina, and I would endeavor to overcome it by the same means. SCOTT ON SCARLET FEVER. 131 With some, I believe, there exists a great prejudice to the lancet during the period of incubation. I think it often happens that the tardiness with which the eruption makes its appearance, is owing to the intense excitement — the severe congestion of the mucous tissue or the active pneumonia, (for I have often seen pneumonia in measles before the appearance of the eruption,) and under these circum- stances I would bleed freely, feeling it was the best means of bring- ing out the eruption and of lessening the consequences of a severe bronchitis or a pneumonia. It frequently happens in this disease, as in scarlet fever, for the first few days during the time of desquama- tion all cause for anxiety about the sufferer is at an end. But in a day or two you find your little patient with fever and with a slight dry cough. He lies all the time with his eyes closed as if asleep. The slightest movement in bed occasions the cough, or he coughs if he speaks. The pulse is frequent and the skin is hot. This is often- times the beginning of an obstinate and dangerous bronchitis. Of course I do not mean to exclude blistering, bleeding, or any other re- source known to the healing art, yet I have never seen any practice so beneficial as calomel, given from time to time, enough to keep the liver acting. I have seen tartarised antimony used in the most de- cided manner from day to day and week to week. I have seen a child pale and nauseated for hours, and yet, even when the remedy was used for days together, I have never seen it produce the slightest fluidity in the cough. Dr. D. said, in the latter part of the debate, that he had purposely avoided pathological and theoretical discussion in the remarks which he had submitted. He would remind his friends who had introduced the views of the text-books, that such high authorities as Andral and others differed widely as to the constitution of the blood in scarlatina. He did not believe in any of the abstract theories on the subject, one being about as good as another. When pathology is more perfect we may deduce from it proper treatment; that now is impossible. Dr. M. P. Scott then read the following paper on scarlatina — the calomel treatment : One would think, from listening to the reports of the wonderful cures performed by calomel, that we had at last found the elixir of of life. What No. G is for the Thompsonian, calomel is for the Alo- pathist. It would be curious to trace its history since its introduction into the materia inedica. There is scarcely a disease which human flesh is heir to, for which it has not been given and extolled as a spe- cific ; even in the present advanced stage of medical science it is sometimes given to fulfil the most opposite indications. No matter what the disease or its stage, calomel is the resort, and if we do not know what is the matter, " still calomel." Of all therapeutical agents its action is the most varied, and one might think, by a little stretch of the imagination, that it changed its modus operandi, according to the disease to be combatted or its stage. Calomel is an antiphlogistic — -calomel is a sedative at one time- — ■ 132 SCOTT ON SCARLET FEVER. at another, it is a stimulant. Now it acts upon the nevous extremi- ties— then again upon the ganglionic system. At one time it increases the secretions of the liver — at another diminishes them ; some think it a liver regulator and rectifier of the secretions of the whole system ; calomel is an alterative, calomel acts by sympathy. It is given in pneumonia for one reason; in typhoid fever, where an opposite condition of system exists, it is also employed — as a remedy for cholera it is highly extolled, given in small and repeated doses and in enormous quantities, its advocates differing as to its effects, ac- cording to the views they entertain of the pathology of that disease. Some give it to increase the secretions, to produce black, tarry dis- charges, which to them are the harbingers of returning health ; others to relax the spasm of the gall duct; others to effect, they know not what, but say experience bears them out in the propriety of its use. Calomel is a useful and powerful remedy, and because it is, I would be guarded in its use — it is capable of fulfilling a great many indications, but it is given. I contend, too indiscriminately. There is none which has been so abused and which has produced such disas- trous effects — in many cases leaving the patient scarred, disfigured, and sometimes maimed for life. The last case that I have noticed is reported in the " Stethoscope," where an operation was performed to remedy the ravages that calomel had made upon some unfortunate who had been doubtless cured by a course of mercuiy. I wish now to say a few words concerning its employment in scar- latina ; but before doing so it will be necessary to go a little into the pathology of that disease, and also to advert to some of the known ef- fects of mercury, and then conclude if such practice is founded upon sound pathological views. If it is not, we should discard it ; for when we throw aside the principles of physiology and the facts drawn from pathological investigations, we leave ourselves a position but little above that of the Thompsonian or Homeopathist, and should no longer practise the science of medicine, but view it as an art to be studied, by observing the effects of certain medicines upon certain symptoms, and giving those medicines when we think we have again met with simi- lar symptoms. It is with some diffidence that I undertake to give my views of the pathology of this disease, deduced from what I have read and ob- served. I hope, therefore, all due allowance will be made if I do not make irryself clearly understood — I may in any event console nryself by the reflection, that I will not have been the only person who has at- tempted and failed in giving a clear idea of the pathology of scarlet fever. If you will take the trouble of examining what has been written upon this subject, you will be surprised to find how few there are who have succeeded in giving anything like a clear account of the causes which produce and the effects which follow scarlatina. Some will tell you that this is an inflammatory disease, and adduce the state of the skin and fauces as evidence of it — they will tell you that the brain is implicated, and ascribe the cerebral symptoms to a congested or in- flamed condition of that organ. SCOTT ON SCARLET FEVER. 133 Some authors, and among them one who in his prime had few su- periors, (Dr. Chapman,) consider this disease as produced by a con- tagious matter which is swallowed with the saliva ; its first action is upon the mucous membrane of the prima? viae, and nature relieves herself by a metastasis to the skin, the general system being deranged by sympathy. This is only the Broussais doctrine, which located all diseases primarily in the stomach or intestines. It is a mere assertion, an hypothesis supported by no facts ; for he has to resort for an ex- planation to the sympathetic action supposed to exist between the jyrimce via, the skin and fauces. The explanation is worth nothing — sympathy being a very convenient word to cloak our ignorance, and should be discarded from the medical vocabulaiy. It is impossible to reason with any one, if, when there is a difficulty to explain, he is al- lowed to resort to an explanation by sympathy. I cannot subscribe to this view. Nor can I agree with those who look upon this as an in- flammatory disease. The fact of there being an ulcerated throat is not enough to establish this view. We might with the same propriety say that typhoid fever was an inflammatory disease, because the glands of Peyer and Brunner were always ulcerated. The eruption is more an evidence of vitiated blood than of inflammation. But how account for the cerebral symptoms ? Certainly the existence of delirium is not enough to prove that there is inflammation of either the brain or its membranes. If, however, such was its condition it would not be dif- ficult to prove it, as post mortem examinations would shew traces of its existence. Graves of Dublin has reported a few cases, where the symptoms were such as to lead him to the conclusion that he had to deal with inflammation of the brain, and he treated them accordingly. His pa- tients died, and upon making the autopsies there was not a trace of inflammation or even congestion. One such fact is worth a volume of theory drawn merely from the S3^mptoms ; it leads us to look for some other cause to account for these symptoms. If we could agree as to what constitutes inflammation, it would be easier to solve the question whether scarlet fever is or is not an in- flammatory disease. A great deal has been written in explanation, and a great many symptoms which accompany inflammation usually, laid down, but these symptoms may also occur when it does not exist, so that they cannot be looked at as pathognomonic. Andral, aware of this, investigated the subject more profoundly, and searched for some change, wrhich always occurred. After examining the blood of more than a hundred patients, he was led to the conclu- sion that in all inflammatory diseases there was an excess of fibrine. Subsequent observation has confirmed him in this opinion. Whether an excess of fibrine is the cause of the inflammation or its product, he was not able to establish ; the co-existence of the two he demonstrated. "An excess of fibrine in the blood is the pathognomic sign of in- flammation." Should we not then expect, if scarlet fever is inflam- matory in its character, to find an excess of fibrine in the blood of the patient? But what is the fact? According to Trousseau and others, 134 SCOTT ON SCARLET FEVER. the blood is less plastic— more fluid than in a normal state. There is also a diminution of red globules ; the blood is altered, but does not present the change which we have seen always to take place in in- flammation. I might stop here, and, if my premises are true, say, that I have established my point, as there is not only not an increase of the fibrine of the blood, but actually a diminution. But, again — if scarlet fever is an inflammatory disease, ought we not to expect that the antiphlogistic treatment would be the most successful? But the reverse is the case, as may be seen by examining the statistical tables of Williams, who gives the results of several modes of treatment — the mortality being much greater under the antiphlogistic. What does Watson sav? " Sometimes it becomes necessarv to bleed, but do it with the finger upon the pulse." But I do not think the anti- phlogistic treatment properly deduced from the symptoms as usually presented. The pulse is frequent, small, and sometimes irregular ; not indirectly, by oppression of the vital forces, but directly, and under the influence of an agent which acts upon the blood, altering it so that it no longer subserves properly the purposes of nutrition, ren- dering it unfit for supplying the different organs with those constituents which are necessaiy for the proper performance of their functions. This cause I think to be some deleterious agent — some poison existing in the atmosphere, which is taken into the system through the lungs. Its effects are first felt by the blood. Here is the primary seat of the disease, the cause a poison. This view is supported by the alterations observable in the blood, acting secondarily upon the nervous system, producing all those de- pressing effects which are seen in scarlet fever. The state of the pulse is that which characterizes the action of most morbid poisons. Another symptom is a malignant sore throat, with a tendency to be- come gangrenous ; another, an eruption upon the skin, through which the poison is probably eliminated and propagated ; if eliminated, of course from the blood. If once we admit that the primary cause is some poison, it seems to me that we should look to its effects upon the blood ; for is it reasonable to suppose that any poison should be taken into the system through the blood, without its affecting this fluid in a deleterious manner — and would not this be felt in turn by the whole system? Cannot the cerebral symptoms be thus accounted for? Is not healthy blood necessary for the proper performance of the func- tions of the brain — for the maintenance of sufficient nervous energ}'- ? ' And would not a vitiated blood cause a general derangement of all the functions of the animal economy — and is not this general func- tional derangement seen in scarlet fever? Why the throat and skin are selected to spend its virulence upon, we are no more able to explain, than why one medicine acts upon the kidneys and another upon the liver— or why one poison will prove fatal by its action upon the nervous system, and another upon the blood. Now, bearing in mind the symptoms, viz : the feeble, frequent pulse, the ulcerated throat, with a tendency to become gangrenous, and more especially the altered condition of the blood, the depression of the SCOTT ON SCARLET FEVEK. 135 nervous system and general debility which exists, I do not think anti- phlogistic remedies called for — bleeding would increase the evil— nor do I think mercury indicated. Let us see what are some of the effects of mercury when its consti- tutional action is produced — and first, upon the blood. It diminishes its plasticity, renders it more fluid, and lessens the amount of fibrine and red globules. Now certainly there is no condition of the blood of a scarlatina patient demanding an agent acting thus upon this fluid — on the contrary, it would appear that there was an indication for an agent which would produce an opposite effect. Mercury would tend to in- crease the general debility which already exists — it is a depressing re- medy. It increases the secretion of the liver, but is not a liver regu- lator— but this gland is not especially implicated in scarlatina. If mercury is pushed too far, it acts as a veritable poison — the alterations of the blood become more manifest, the face is bloated, the legs swoln — general anasarca may be produced. Its effects upon the nervous system now shew themselves : there will be extreme debility, ner- vous tremor, the brain becomes involved, and according to Trousseau, presenting symptoms somewhat resembling mania a jpotu, &c. Now, what indication have we for mercury ? Not to combat inflammation ; for, if the view I have taken be correct, it is not an inflammatory disease. There is general debility and a tendency to assume a ty- phoid state. Would not mercury increase these symptoms — does the feeble, frequent and irregular pulse call for calomel? Cases of scar- latina might be cited — complicated with something else, which might de- mand the moderate use of the lancet and of calomel, just as in typhus fever we may have to combat an affection of the lungs by bleeding or tartar emetic ; but no one will on this account recommend such a course in genuine typhus fever. It may be said, that, taking the view that a poison of some kind is the cause of the disease, the indication would be, either to neutralize it by some antidote, or, failing in that, to assist the efforts of nature in eliminating it. The means which she employs operate through the various emunctories, particularly the skin. Now is not here an indi- cation for calomel? Does not it act upon many of the emunctories, increasing their activity? Indeed it acts upon the skin itself. True enough ; but we lose sight of the other effects of mercury, and to do a little good, would do much harm. I may further answer, that we have other means of arriving at the same end, and by a safer route. We have the class of diaphoretics for the skin, diuretics for the kid- neys, &c. ; and it seems to me that in this channel our remedies should be directed, merely aiding the efforts of nature. By what we call the " heroic practice," we exhaust her resources without affording relief from the enemy which is preying upon her vitals ; and when at last, seeing the inutility of our efforts, we cease, and leave her to her own exertions, she has no longer strength to rally from the double attack of the disease and the doctor. I wish to say a few words of a mode of treatment suggested by Dr. Schneeman, physician to the king of Hanover. He proposes to cure scarlatina by greasing the skin with fat bacon. His treatment is 136 SCOTT ON SCARLET FEVER. based upon the opinion, that the skin performs probably the most im- portant office in the human system ; that it throws off a large quan- tity* of matter which, if retained, would disturb the functions of the other organs, by giving to them a task for which they are unfitted ; that the affection of the throat is due to this cause, and is cured or prevented from occurring by a resort to fat bacon, and so with all the other parts or organs implicated. Scarlatina is then, according to his view, essentially a disease of the skin. We are not told what causes this disease of the skin. I should like to go more than skin deep, when probably we might find, that what in the first place gave origin to the eruption would account for some of the other symptoms. He compares the eruption to a scald. Now there is very little analogy, if we may judge by the results produced. In a scald, the entire skin is suddenly destroyed, and consequently its functions are immediately suspended. In scarlet fever, there is not a total destruction of the skin, nor is the whole of the skin diseased, neither are its functions altogether suspended ; for new skin forms as desquamation proceeds. If there is such an analogy, we ought to expect to behold some of the symptoms of scarlet fever as a consequence of a burn. As he has referred to a scald as an analogous case, I would sug- gest other skin diseases as presenting a condition more similar to scarlatina than a scald : for example, measles. If this remarkable relation exists between the skin and throat, a disease of the former causing an affection of the latter, we might reasonably expect to meet with the sore throat as a consequence of an attack of measles. But no; he will tell you, I suppose, that here there is some peculiarity which causes the mucous membrane of the bronchial tubes to be af- fected. But we meet with other diseases of the skin which derange its functions more than either scarlatina or measles : as pemphigus, where the entire cuticle is gradually destroyed, the patient presenting a miserable condition. This disease is always fatal, and if Dr. Schneeman's views are corrective might expect to behold these s}rm- pathies and unknown relations existing in all their force. But have we any of the symptoms of scarlet fever? Do we see the sore throat ? Have we cerebral complications ? No, none of these ; but the patient lingers out a miserable existence, dying by inches ; and upon post mortem examination there is only one internal organ found diseased, viz. : the liver, which is always found fatty. With more propriety I might contend for some direct relation between the skin and liver. There are also other skin diseases, as urticaria, eruthema, psoriasis, &c, which derange the functions of the skin, yet in none of these are seen symptoms resembling scarlatina. Again : if the views of the doctor are correct, why do we see the symptoms which he would make dependent upon the eruption occur in a more malignant form when there is no eruption ? Why are we told by those experienced in this disease that the fading of the eruption is a bad sign; and indeed some will tell you to use all your efforts to bring out the eruption fully? There is another circumstance which is against this idea, namely, that the mildest cases of scarlatina are always attended with the eruption. Sydenham tells us that it is only BOLTON ON CATARACT. 137 dangerous through the officiousness of the doctor, yet he describes this as an eruptive fever. In one part of his article on this mode of treatment, the doctor says, so beneficial is its influence upon the organs attacked by the malady, particularly those of the throat, that the normal condition is in every case and in every part speedily restored. In another portion he speaks of the cerebral complications at the commencement of scarla- tina, which are to be met by bleeding, which he goes on to say is the sheet anchor ; he also uses mustard plasters to the shins. Now it ap- pears to me that there is some inconsistenc}r ; first, he views the erup- tion as the cause of all the attendant evils which are remedied by the " fat bacon," and a few pages on says that our sheet anchor, when the brain is implicated, is bleeding. It seems to me, if his first view is correct, his remedies to meet the cerebral affection are wrong — he ought still to use his "fat bacon," which is to remove the eruption, which is the cause of the complications ; or does he view the cere- bral complications as unconnected with the main disease — as some- thing superadded and to be treated apart; as an inflammation of the brain, not proceeding from the cause which in the first place produced the disease ? Such an opinion cannot be sustained. It does seem to me that the doctor takes a very superficial view of the pathology of scarlet fever, and I have no idea that his fat bacon treatment will work the wonders he ascribes to it. I have heard of a few cases which have been treated in this manner, with the effect of allaying the itching, for which it is doubtless very good. Another re- commendation is its extreme cheapness, placing this remedy within the reach of every Christian. Alas! for the poor Jews. Watson recom- mends it as a coating for the protection of the tender skin during des- quamation, which I am inclined to think is the best use it can be put to in the treatment of scarlet fever. Dr. Brooks presented a table of the post mortem appearances, according to the different pathologists. A very interesting debate was carried on until half past 11 o'clock. Drs. Bolton, Minor, Little, G. A. Wilson, Snead, Haskins, Parker, Rives, Gooch, and C. P. John- son took part. We regret that it is impracticable to give their re- marks. The following paper was then presented and laid on the table : The Catoptric Test for Cataract. BY JAMES BOLTON, M. D. The diagnosis of cataract is often extremely puzzling. In amauro- sis, an opacity is often observed behind the pupil, which resembles an opaque crystalline lens. When we consider the extreme value of the affected organ, and the totally diverse methods of treatment applicable to the two diseases thus liable to be confounded, we are prepared to place a high estimate upon any means which may enable us to form an accurate diagnosis. 18 BOLTON ON CATARACT. If the opacity be produced by inflammation of the vitreous humor and retina, the puncture and laceration of these tissues, required by the operation for cataract, would probably increase the existing inflam- mation, and render the case hopeless. When the anterior surface of the lens is opaque, owing to loss of transparency of the anterior surface of its capsule, or of its substance, or of both combined, the diagnosis is comparatively eas}^ There are three principal points which distinguish the opacity from an affection of the vitreous humor. 1st. Its position. It appears nearly in contact with the iris at its pupillary margin. 2d. Its form being convex. 3d. It does not disappear on taking an oblique view of it. Opacity of the vitreous humor is more deeply seated ; its form is concave ; and it can be seen only by a direct front view. When the posterior surface of the lenticular capsule has lost its transparency, the opacity corresponds, both in form and position, with opacity of ihe vitreous humor ; and the resemblance will be still more perplexing if the cataract be in the nascent state. In such cases, the highly philosophical, delicate and accurate test of Sanson, called also the Catoptric Test, is of inestimable value. The following is a description of it : If a clear flame of a candle be held before a healthy e}^, there will be seen upon the surface of the cornea, a bright, well-defined image of the flame, erect, and very much diminished in size. On looking deeply into the eye, through the pupil, there will be seen a faint, bluish image, with an outline not well defined, erect, and larger than the first. Between these two may be seen a third image, bright like the first, very clearly defined, much smaller than the other two, and inverted. There are then two erect images, and an inverted one between them. On moving the candle across the eye, the erect images will be ob- served to follow it, while the inverted one moves in the opposite di- rection. The outer one traverses the entire cornea, and the other two pass no farther than the margin of the pupil. These phenomena are explained by the fact, that when a ray of light penetrates a healthy eye, it encounters three reflecting surfaces : first, the convex cornea ; second, the convex anterior portion of the lenticular capsule ; third, the concave posterior portion of the same membrane. The two first and second reflect upright images ; the third, being a concave mirror, reflects an inverted one, which falls be- tween the other two, in consequence of that being the position of its focus. These images furnish us with very important indications. Obliteration of all three images indicates opacit3T of the cornea, without giving any information as to the condition of the interior struc- tures of the eye. Obliteration of the inverted image only, indicates opacity of the posterior surface of the lens, with transparenc}^ of its anterior surface, and of the cornea. Obliteration of the posterior erect image indicates opacity of the anterior surface of the lens, and must necessarily be accompanied by obliteration of the inverted one. The most important of these images is the inverted one. If that can be made out distinctly, there is no cataract ; for the posterior sur- Johnson's medullary sarcoma. 139 face of the lens must be clear, in order To reflect the rays of light, and the body and anterior surface of the lens must be clear, in order to transmit these rays. In amaurosis, therefore, all three images are visible ; in cataract, when fully formed, only one, the corneal image, can be seen. But this method of diagnosis is available for the detection of not only matured cataract, but such is its mathematical precision, thai the least departure from a healthy condition of these reflecting surfaces is invariably indicated by a corresponding departure from the normal appearance of the images which they present. It not only detects the existence of cataract, but indicates its state of progression from incipiency to maturity. In the whole range of medical science, 1 know of no method of de- tecting disease more beautifully illustrative of physical science, and none which may be relied on with more implicit confidence. The following case, although unfortunate in its termination, exem- plifies these remarks in an interesting manner : J. F., bookbinder, about 50 years of age, intemperate, has been blind in the left eye for several }7ears, during which it has been sub- ject to attacks of inflammation. There is sufficient vision to distinguish night from day. Behind the pupil, and very deeply situated, is an opacity of a brownish muddy color. Its form is indistinct. The sight of the other eye is defective, but all the images are visible. Diagnosis. — Opacity of the posterior part of the capsule of the right eye, with probably some degree of amaurosis, which already exists in the left eye. Operation. — Anaesthesia was produced by chloroform. An incision was made in the superior margin of the cornea, through which the lens was extracted. On the posterior surface of the capsule was an opacity, darker at its centre and shaded off to an undefined edge. The diagnosis was therefore accurately confirmed. The patient was confined to bed, cold water was applied locally, and a strictly antiphlo- gistic regimen enforced. On the fourth day the patient accidentally used the eye for a moment, and distinctly saw some small object. In a day or two more the eye was suddenly attacked by violent inflam- mation and pain, which were relieved by active antiphlogistic mea- sures, but the eye became hopelessly amaurotic. Case of Medullary Sarcoma of the Right Breast. Reported by Carter P. Johnson, M. D., Professor of Anatomy and Physiology in the Medical Department of Hampden Sydney College. Mrs. J was admitted into the infirmary of the medical college on the 1st of May 1849. She is about 45 years of age — says that her general health is good, though her complexion is cachectic. The disease originally made its appearance in June 1847, and was removed in December of that year by Dr. Spencer of Petersburg, the 140 Johnson's medullary sarcoma. wound healing well. It made its re-appearance in June 1848, since when it has increased with great rapidity, especially within the last three months. At the present time, May 1849, the tumor extends from an inch above the clavicle to the eighth rib, and from the margin of the axilla to the edge of the sternum. It measures 2 feet in cir- cumference at its base, 14 inches in its vertical, and 11 inches in its transverse diameter. Its appearance is nodulated^ and the integu- ments at some points are inflamed ; at these points softening appears to have taken place, but no ulceration. Having been fully apprised of the danger of the operation and of the probability of the return of the disease, the patient still insisted on the removal of the tumor. Accordingly, on May 3d, the patient having been placed fully under the influence of ether, I commenced the ope- ration, assisted by Drs. Gibson, Conway and Peticolas, by a long cir- cular incision, beginning at the inner side of the axilla, and passing in succession around the upper, inner and lower portions of the circum- ference of the tumor. I then rapidly commenced the dissection from within outwards. The enlarged vessels feeding this immense mass sprung in rapid succession as the knife passed through them, but were well controlled by the gentlemen assisting me. The tumor was found to embrace the pectoral muscle throughout its entire thickness, and to rest immediately upon the ribs and intercostals. Having carefully separated these deep-seated attachments, the operation was completed by dividing the integuments attached to the external portion of its cir- cumference. Five or six vessels were then ligated. The tumor was found to weigh 4£ pounds ; on microscopic exami- nation, it exhibited caudate cells of various forms and sizes. The patient lost a good deal of blood during the operation, and was excessively prostrated, rallying only partially after the lapse of an hour, under the free administration of stimulants. The wound was dressed with lint spread with simple cerate, and 75 drops of laudanum with 2 ounces of brandy administered. Reaction was slow, and her condition during the evening was critical. May 4th. Has rallied somewhat ; wound dressed as before ; beef tea ordered as her diet. May 7th. Has continued to improve slowly under the above treat- ment; wound beginning to suppurate freely. May 8th. Suppuration very free and offensive ; ordered simple water dressing, covered with oil silk, twice a day — wound to be washed at each dressing with solution of chloride of lime. May 9th. Suppuration much diminished ; but little fetor about the wound ; pulse feeble and appearance very cachectic. Ordered precip. carb. iron 5 grs. three times a day, and a tablespoonful of milk toddy every two hours. May 12th. Wound looking more healthy; suppuration slight ; gene- ral condition somewhat improved ; increased carb. iron to 10 grs. 3 times a day, and continued the milk toddy. May 14th. Toddy discontinued ; wound beginning to fill up ; gene- ral condition improving. May 19th. Improvement since last report very decided ; the wound Johnson's medullary sarcoma. 141 is filling up from the bottom ; suppuration is very slight ; there is no appearance of granulations, but the surface is smooth, though florid ; the process of modelling is evidently going on, gradually filling up and contracting the wound. Increased carb. iron to 15 grs. three times a day. May 24th. Wound continues to fill up rapidly, and its whole ap- pearance is improving, with the exception of a spot on the cartilage of the third rib, which was touched with the knife during the operation, and now shews some tendency to ulceration. Ordered a pint of por- ter in addition to the iron. May 25th. Complains of a sense of fullness and pain about the lower portion of the abdomen. Relieved by an enema and the appli- cation of hot cloths over the abdomen. Carbonate of iron disconti- nued and substituted by sulphate iron, grs. 12, water oz. 6 ; teaspoon- full three times a day. June 5th. Wound filling up and beginning to cicatrize from the edges ; the cartilage of the third rib has become completely denuded, and ulceration taken place along its upper and lower edges and inner surface, a probe passing easily under it ; the cartilage and sternal por- tion of the rib was to-day removed to the extent of 2 inches. A por- tion of the cartilage of the fourth rib, which was exposed during the operation, but not touched, shews also a tendency to ulceration. June 8th. Suppuration from the cavity left by the removed costal cartilage very abundant ; the cavity filling up by granulation ; the 4th costal cartilage becoming extremely denuded, and ulceration com- mencing at its upper and lower edges. Patient still occasionally com- plains of pain and sense of weight in abdomen. Her appetite is fail- ing and the stomach becoming irritable. Ordered her to stop the sul- phate iron and to continue the porter. June 12th. Cartilage of the 4th rib having, by the extension of the ulceration, become separated from the subjacent tissues, was removed by a chain-saw to the extent of l£ inches. Suppuration from the two cavities left by the removed cartilages continues very abundant ; sto- mach becoming more irritable ; occasional restlessness. Brandy and water substituted for the porter, with an anodyne at night, as occasion may require. June 26th. Since the last date, the irritability of the stomach has con- tinued almost incessantly, causing patient to reject all food and almost every medicine attempted to be introduced to remedy this condition ; she has been gradually growing more feeble, and for the last few days has been occasionally irrational. Since the 20th inst. the second rib and its cartilage, which were not exposed during the operation, have shewn a disposition to ulcerate. The general appearance of the wound has, within the last few days, become unfavorable, the healing process having ceased, and the hitherto florid appearance superseded by a pale and flabby condition ; she died this morning at 12 o'clock. Post mortem. — Thorax — The left side was found healthy ; on the right side, the lung was healthy ; there was general adhesion between the costal and pulmonary pleura ; and, extending from the 2d to the 5th ribs, just under the points at which the ulceration of the cartilages 142 DAVIES ON AMENORRHEA. and the ribs had occurred, a strong coat of lymph was found on the outer surface of the costal pleura, covered externally by several la}*ers of granulation. The pericardium and heart were normal. Abdo- men— Stomach healthy, with the exception of some softening of the mucous membrane about the pylorus ; intestines blanched, but other- wise healthy; liver pale ; spleen, kidneys and bladder healthy; uterus presented several tumors ; two small encepholoid masses occupying the fundus on either side of the cavitv, each about half the size of a hen egg ; developed apparently in the peritoneal coat of the uterus, on its posterior surface, and connected with that organ by small pedi- cles, were three tumors, each about the size of a partridge egg, nodu- lated upon their surfaces, and presenting at several points in their inte- rior depositions of osseous matter. In reflecting upon the foregoing case, the following points have sug- gested themselves to my mind : 1st. The history of this case affords another illustration of the very unfavorable issue of operations upon malignant diseases, although the general health of the patient may be good, and the whole of the local affection may be removed. 2d. It illustrates the great superiority of water-dressing in wounds where a large surface is exposed, preventing, as it does, the formation of pus- globules, and favoring the modelling process of McCartney, thus saving the patient from an immense drain upon the nutrient elements. 3d. I have never been able satisfactorilv to explain the cause of the denuda- tion of the 3d and 4th ribs, neither of which were touched during the operation, and of the ulceration of the muscular tissue attached to them, while the other portions of the wound were rapidly healing, and the general condition of the patient improving. 4th. This case illus- trates very beautifully the protective power of nature in guarding the cavity of the thorax from the effects of the ulceration going on in the intercostal spaces ; and 5th. It illustrates the frequent co-existence of malignant disease in the breast and the uterus, the probability of which should always be taken into consideration in deciding upon the propriety of the operation. Remarks on Amenorrhosa, with Cases. BY JOHN B. DAVIES, M. D., OF CABIN POINT, SURRY COUNTY. Derangement of the uterine functions have so often been the subject of comment, and the theme of such crude suggestions from novices in the profession, that I feel some delicacy in exhibiting my experience to the public in the form of an essay, for fear of being considered pre- sumptuous, or having the triteness of the subject charged upon me ; but when I know what I state to be facts, untinctured with any vision- ary or theoretical speculations, and tending to lessen the suffering of the females of our land, by oivinsf extensive diffusion to all knowledge 111 ' 'J o , .o "J calculated to ameliorate a most painful and dangerous disease, I am prompted by higher, and, I trust, nobler motives than the mere aspira- tion of the empty bubble applause, and feel impelled by duty and be- nevolence to offer my mite in the accomplishment of so desirable an DAVIES ON AMENORRHEA. 143 object. It is unnecessary here to detail the symptoms, as all are con- versant with them, and I shall only mention such as occurred in the following cases : Case I. — In 1S-39 I was called to Miss R. of Chesterfield, aged 24, who had not menstruated in seven years. Pain in the head and back, leucorrhcea, chlorotic appearance, some fever, bowels costive, tongue white, numbness down the thighs, tumultuous action of the carotids, fulness of the abdomen, palpitation of the heart, a periodical monthly discharge from the uterus of a greenish fetid character, producing excoriations about the vulva, some dysury and globus hystericus. I ordered the following: One pill at bed time, one next morning before breakfast, and one at 12 o'clock, unless the two first operated. Then omit a night and day, and resume, continuing this course until the liver disgorged itself of its morbid secretion, and healthy action was evi- denced by yellowish discharges: ft Mit. hyd. chlo. 3 j. Socot. aloes 3 j. Sapo. castil. grs. v. Tart, antim. grs. ij. — Mix — make x pills. If it happened, as it does sometimes, to be insufficient to produce the necessar}' evacuation, follow the third pill in four hours with a dose of oil and turpentine. Use red oak bark and alum, alternated with chamomile and flax-seed tea, as tonic astringent and lubricant va- ginal injections. This is a bold, but highly excusable robbery of the hymen, enriching her untainted honor with the choicest blessing, health, before which this bubble in the ocean of pleasure sinks into insignifi- cance. It is only in cases of fetid uterine discharge that I resort to vaginal injections in the unmarried, or when the leucorrhcea is severe and obstinate. So soon as the digestive functions assumed healthy action — which, en passant, I take occasion to say are always deranged in these cases, and too much overlooked — I ordered a teaspoonful of the following mixture three times a day: ft Vin. tinct. sanguinariae canadensis, § ij. Tinct. Valerianae, 3 j. " dyttae, 3 v. Syrupi. simp. 3* vij. M Keeping the bowels regular with the pills as before directed. Here we fill three indications, the first a tonic and emmenagogue; the 2d, calming nervous excitability, and the 3d, relieving the leucorrhcea* One remarkable feature in this mode of treatment is, that preparations of iron, as in ordinary anemic conditions of the system, are scarcely ever necessary — all obstruction being removed, all the functions come into action, and healthy blood is generated from the newly established and improved laboratory. I may be too sanguine, too much imbued with the spirit of enthusiasm, but in all candor and truth, I believe this treatment as much a specific in amenorrhcea as quinine in intermittent fever. I have never known it to fail — I have given the prescription to many of my medical friends, and I do not believe one has been disap- pointed. 144 SURGICAL CLINIQUE. For this preparation, the mixture, T am indebted to my friend and former partner in the practice, Dr. Francis J. Mettauer of Petersburg; a practitioner whose enlightened views and distinguished medical skill are properly appreciated where known, but one whose unobtru- sive diffidence and innate modesty have obscured the lustre of his medical talents. Case II. — A negro, belonging to Mr. Sublett of Powhatan, had la- bored under that disease for three years, complained of nearly every symptom except the periodical monthly discharge. The same treat- ment with the same success. I could mention mnny more, but it is unnecessary, as the same treatment was pursued. Surgical Clinique of Richmond Medical College. Service of Dr. Gibson — February 8, 1851. REPORTED BY ALFRED B. TUCKER, RESIDENT STUDENT. Dr. Gibson exhibited to the class this morning a negro boy 13 years old, with enlargement of the right side of the lower jaw. The boy's master, Mr. Baylor of Essex, states that this side of the bone has always been larger than the other, even from birth, but that it be- gan to produce deformity about two years since, and had increased considerably within the last six months. The patient's condition at present is as follows : On opening the mouth, there is seen an irregu- lar tumor, extending from the first molar tooth to the angle of the jaw, and apparently including the roof of the coronoid process. This tumor is very dense, and is apparently composed of bone alone, without any admixture of fleshy fibres or of cartilage. There are no teeth attached to it, and the only interruption to its surface is a rugged opening, through which a probe may be passed an inch in depth. This open- ing may be some two or three lines in diameter, and is on the inner edge of the tumor. The external aspect of the tumor, as observed, covered by integument, is irregularly elongated, and presents the same dense feel when handled. The tumor is free from pain, and has alwa}rs been so, even when rudely examined. The boy's consti- tution has been in no way involved by this affection. There are no general symptoms — but he is entitled by hereditary predisposition to the strumous diathesis, and manifests it by certain characteristics. Dr. Gibson remarked, that the diagnosis he should be disposed to make in this case was, that of spina ventosa or cellular exostosis — a disease non-malignant in character, and injurious chiefly by its dispo- sition to increased enlargement, whereby the functions of mastication and deglutition are impaired, and from the pressure of which impor- tant parts, as the larynx and oesophagus, may ultimately suffer. Dr. Gibson said that he thought the indication in the treatment of this case was to remove the diseased bone, not because of actual in- convenience at this period, but because, judging of its future advance SURGICAL CLINIQUE. 145 by its progress in the last six months — it was much to be feared that its removal would become necessary at no distant period, and he con- sidered that every month's delay must add to the difficulties and dan- gers of the operation. Accordingly, he should proceed to remove the disease by disarticulating the condyle of the jaw of the right side, and by section of the bone near the symphisis. The boy was laid upon the table and caused to inhale chloroform from a sponge held in a little piece of cotton cloth, and after some four or five minutes became un- conscious. The first incision was made, beginning over the condyle, and extending down in a straight line to the base of the jaw- — here another incision was commenced, extending along the base of the jaw until it reached a point corresponding with the corner of the mouth — a third incision was then made from the end of the second, directly upwards to the lip, stopping at the margin of the lip, and thus leaving it intact. The facial branch of the carotid artery was necessarily di- vided in the second incision, and its haemorrhage was controlled by the pressure of Dr. Johnson's finger. The flap thus formed by the three incisions was dissected up, and the tumor brought clearly into view. The second bicuspid tooth was now extracted, and the soft tissues being incised from the bone at this spot, it was cut through, partly with the straight saw and partly by means of powerful bone pliers. The bone being separated, was now held in the left hand, and the surgeon began the work of separating the attachments to it within the mouth. This was concluded with but little haemorrhage. The bone being depressed forcibly, and as a lever, the coronoid process was separated from its muscular connections, and finally the condyle was removed from its capsular attachments, and the whole mass brought away. Some delay was occasioned at this stage of the ope- ration, perhaps in consequence of the enlarged and expanded condi- tion of the coronoid process, which had been altogether changed in form by the extension of the disease into it. The patient also mani- fested considerable though momentary pain, when the inferior dental branch of the 5th pair of nerves was cut across. After securing the facial artery by ligature, the edges of the flap were accurately ad- justed by means of the interrupted suture and the isinglass adhesive plaster. A piece of lint soaked in cold water was applied over the wound, and covered with oil silk, and the patient was removed from the operating room. Examination of the diseased bone verified the diagnosis expressed . February 11th. Dr. Gibson announced to the class that he intended to-day to per- form the operation of extirpation of a diseased testis, in the case of a man who had been in the infirmary during the last five or six weeks. This man, it seems, contracted gonorrhoea whilst at work in a factory in Manchester, about a year ago, and had orchitis supervening upon it in May last. The inflammation of the testis resulted in suppuration of the gland, and when he entered our institution he had gonorrhoea! discharge, and purulent secretion from two sinuses which led into the 146 SURGICAL CLINIQUE. testis. He was placed upon appropriate treatment, and in a short time the urethral discharge ceased, but no amendment was observable in the condition of the testis ; on the contrary the sinuses increased in depth and communicated with each other, whilst the general health began to be impaired; loss of appetite, evening exacerbations of fevers and night sweats, all marking the general effect of the local malady. Under these circumstances, Dr. Gibson said that he deemed it expe- dient to perform the operation of removing the diseased testis, believ- ing as he did, that the arrest of the dangerous constitutional symptoms referred to would be favored thereby. He remarked that the opinion had often been expressed that the operation of castration was too fre- quently performed unnecessarily, and that many very distinguished surgeons limited its employment to cases of malignant disease occur- ring in the organ ; but that whilst he was willing to believe it had been often needlessly performed, he could not subscribe to the limita- tion of it to malignant disease. Indeed, he remarked, he conceived the case before us to be one which not only admitted of, but loudly demanded the operation, as the life of the patient, threatened as it now is by hectic, might perhaps be saved by means of extirpation of the testis, whilst in cases of disease undoubtedly malignant there is too much reason to fear that no operation whatever might prove availing. Dr. Gibson stated that the ordinary mode of performing castration was this : The patient being placed on his back near the edge of a narrow table, with his feet supported by chairs — the surgeon sits or stands between his thighs, and grasping the scrotum (which, with the pubes, has been previously shaved,) with his left hand, makes an in- cision through the tunics of the testes, commencing at the external abdominal ring, and ending at the bottom of the scrotum. This in- cision exposes the gland — the cord is now detached from its connec- tions, and being held by an assistant, is cut across, and the testis is af- terwards dissected out from its attachments. Dr. Gibson stated that he had never yet performed the operation of removing a diseased testis, but that on this occasion he should not pursue the plan usually recommended, because he had seen in the " Abeille Medicale" of 15th April 1850, an account of a suggestion of M. Jobert, as to a new mode of performing the operation, which he thought superior to any other. He stated that one of the inconve- niences of the ordinary operation is the leaving of a deep cavity in which the fluids accumulate, and very much interfere with immedi- ate union. M. Jobert's suggestion is to make a sort of bi-valve flap, exposing the testicle by a semi-circular incision, with the convexity downwards. The scalpel is entered at the margin of the external ring and carried from above downwards, along the external and ante- rior portion of the tumor, as far as its base, where it takes a turn to the inner side and remounts towards the ring, without, however, be- ing carried quite to it. The lips of the wound open almost of them- selves, and it is only necessary to carry the scalpel, first under the anterior and afterwards under the posterior flap, in order to isolate the testis. The cord is now divided, and its arteries tied. There MEDICAL CLINIQUE. 147 thus remains a sort of shell, of which the two valves are perfectly adapted to each other, and are consequently in a condition the most favorable for immediate re-union, which is not in this, as it is in the ordinary operation, interfered with by the stagnation of the fluids. Dr. Gibson having thus explained the operation of Jobert, pro- ceeded to place the patient under the influence of chloroform, which was accomplished in about 12 minutes — after which he extirpated the testis in the manner referred to. The only haemorrhage that occurred, and this was exceedingly slight, was from a small cutaneous artery — not requiring the ligature. The arteries of the cord were tied, not because they poured out blood, but for fear of subsequent bleeding. The interrupted suture and the isinglass plaster were employed in bringing the valve flaps into ac- curate adaptation, and the cold water dressing then applied by means of the T bandage, and the patient removed from the amphitheatre. Medical Clinique. Report of Two Cases of Paralysis, occurring in the Infirmary of the Medical Department of Hampden Sydney College — Service of Prof Tucker. Communicated by Samuel C. Gholson, Resident Student. Case I. — George, a negro boy, aged ten years, property of Dr. Pollard, entered the infirmary of the Hampden Sydney medical college on the 21st day of December 1850. He, upon examination by Professor Tucker, was found to be afflicted with paraplegia. The loss of motion in the lower half of the body was complete, but the anaesthesia was only partial. Of his previous history we know no- thing, except what was obtained from the boy himself, and that, of course, was indefinite. He worked in a tobacco factory ; had never received any injury from fall or otherwise. The paralysis super- vened gradually, its first approach being only manifested by insta- bility of the lower extremities, attended with irregularity of motion. He had been visited several times by an able practitioner of this city, the paraplegia having existed two months previous to his ad- mission in the infirmary. It seems, from the note that accompanied him, that his recovery was despaired of, his condition hopeless, and that he had been sent here, as a dernier ressort, by the agent of his master. We may add here, that the boy was supposed to be in- fected with entozoa. He never voided worms, by stool or otherwise, during his stay here. Prof. Tucker stated, that hemiplegia was the usual form of paralysis observed in cerebral apoplexy, softening, &c. ; whereas, in spinal hae- morrhage, or in softening of the spinal marrow, &c, though hemiplegia may exist, it is commonly temporary, the paralysis assuming, after a longer or shorter time, the form of paraplegia, or paralysis of motion and loss of sensation in all that part of the body supplied with nerves emanating from a point below the seat of spinal disease. In this case, taking into consideration that the intellectual faculties of the 14S MEDICAL CLINIQUE. boy were unimpaired, that the power of motion and sensation in the upper extremities was perfect, he deemed it admissible to infer that the lesion existed in the medulla spinalis only. This lesion he sup- posed to be ramoUlssement or softening of the spinal cord, but stated at the same time, that in diseases of such long standing, and whose seat was so inaccessible as those of the cerebro-spinal axis, it was impossible to make a certain diagnosis, the more especially when but little was known in reference to the previous history of the patient. That the diagnosis could only be verified with absolute certainty, by an actual examination of the parts implicated, and this, he thought, from present appearances, we would have an opportunity of doing in the course of a few weeks. Presuming that the usual routine of remedies had been already em- ployed, after ablutions to remove the filth that had accumulated upon the person of the patient by want of a proper regard to cleanliness, a purgative dose of calomel and jalap was administered to evacuate the alimentary canal of any vitiated secretions or other irritants that might exist in it. This was followed by the exhibition of strychnia, in doses of iV of a grain three times a day, increased by xV every second day. Stimulating frictions were also exercised upon the lower extremities and over the vertebral column. The administration of strychnia, as above laid down, was continued for a week, when marked convulsive movements of the muscles of the legs occurred — its use was then in- termitted, and its effects rapidly disappeared. During all this time, the patient remained utterly helpless, passing his fasces and urine in the bed, all the power of the sphincters being lost. The strychnine was resumed in doses of -^j of a grain three times a day, and con- tinued until rigid contractions of the paralyzed limbs supervened, at- tended with spasmodic movements of the muscles of the extremities, particularly when irritated by being touched. The patient mean while emaciated rapidly ; ulcerations of the nates were produced by con- tinued pressure. There was perfect anorexia. The palliative treat- ment was resorted to, and occasional hypnotics exhibited for the pur- pose of procuring the necessary rest. Milk toddy was given to sup- port the flagging energies of the patient. The strychnia was never re- newed, but its effect continued until the death of the patient, which took place on the 7th of February. Post mortem. — The vertebral canal was laid open from the middle of the dorsal region to the extremity or apex of the sacrum, but no lesion presented itself to which the grave symptoms that attended this case could be justly referred. There was considerable congestion in the plexus of veins about the vertebral canal, but there is room to con- jecture whether this would produce the paraphlegia. It is to be re- gretted that the whole medulla was not examined — a neglect which renders the case much less interesting and instructive than it would otherwise have been. Case II. — Werter, a negro man, aged 45 years, entered the in- firmary of the medical department of Hampden S}^dney college on the 22d of January 1851. The following symptoms were presented in MEDICAL CLINIQUE. 14$ his case: — Paralysis of the left side and entire loss of sensation, features drawn towards the right side in consequence of paralysis of muscles of the left j tongue, when protruded, turned towards the unaffected side. His sight seemed to be somewhat impaired, his hearing was perfect. He appeared drowsy and as if verging upon coma, though he could be readily aroused from his lethargy ; breath- ing somewhat labored, pulse full and slow, but not incompressible. The radial artery of the right side presented evidences of ossification. Previous history only gained from the patient. He stated that he was a workman on a canal freight boat, had suffered from repeated attacks of vertigo, and in the present instance fell suddenly whilst en- gaged in his work. This occurred three days before his admission into the infirmary. He used ardent spirits ; in person he was corpulent ; neck short and very stout. He had not been treated, as w7e could learn, before he came into the infirmary, and had never suffered from an attack of a similar nature to this one before. Professor Tucker saw him on the 22d ; said that he supposed him to be laboring under an attack of apoplexy or its consequences, pro- bably softening of the cerebral substance, from irritation and inflam- mation produced by the clot. ; that the disease existed in the right hemisphere. Explained why he thought so, stating that the fibres of the anterior pyramids of the medulla-oblongata decussated' — hence the paralysis of the left side. Professor Tucker also remarked, that in all probability there existed ossification of some of the arteries of the brain. Treatment. — Cupping at back of the neck, mustard pediluvia, as hot as the patient could well bear, sinapisms to the ankles, thighs and breast. 23rd January. — Small doses of calomel and ipecac. ; that is, calomelanos, grs. ij ; pulv. ipecacuanha, gr. i, every 4 hours. Jan. 24th. — Calomel and ipecac, continued — blister over the right hypo- chondrium — size about 5 by 10 inches: during all this time the pa- tient passed his faeces and urinated involuntarily. 25ih January. — Cal. et ipecac, continued — purging considerable ; gum opii gr. -J ad- ministered— 'Cupped over the nuchas again. 26th. — Salivated — mer- cury discontinued- — he was purged freely. 27th.- — Blister at back of the neck. Diet of the patient mild, unirritating and fluid. The act of mastication and deglutition performed, with difficulty even pre- vious to salivation. 28th. — Condition unimproved, complained of want of sleep. Sulph. morphias gr. £, exhibited at night — obtained some sleep from it. Seemed better on 29th, though still approxima- ting a comatose condition — mouth continued sore — no ulceration took place — patient asked for apple- water. He continued pretty much in the same condition, passing his fasces and urine involuntarily, breath- ing somewhat stertorously, between sleeping and waking, until the 8th of February, when he died about 3 o'clock, P. M. It is perhaps worth while to state, that after a few days the tongue was protruded naturally — that is, without any forced inclination to the right side. For several days previous to death the patient was annoyed with in- cessant hiccoughs — to relieve which, bismuthi subnit. grs. ij et ex- tract hyosciami g. i was exhibited every 3 hours. The post mortem examination was conducted by Professor D. H. 150 EDITORIAL. Tucker and Professor C. P. Johnson. It was very interesting — parti- cularly so, for the reason that the lesions found fully explain the symptoms that existed during life. The pia mater presented a beau- tiful array of vessels, though obscured here and there by patches of coagulable lymph, having underneath a jelly-like substance. In the sub-arachnoid space a considerable amount of serum was effused. The amount, including a small quantity of blood, which was mingled with it, measured four ounces, and when treated with nitric acid, a large quantity of albumen was precipitated. The arachnoid membrane was opaque and thickened. Its consistence was considerably in- creased. The structure of the left hemisphere of the cerebrum was comparatively healthy, whilst that of the right side was softened, pulpiform, and even puruloid in character. Before the substance of the brain was incised, the existence of a large depression over the seat of the ramollissement enabled us readily to distinguish the diseased from the healthy hemisphere. There was not much unnatural effu- sion into the ventricles. Some of the arteries at the base of the brain, chiefly the posterior, communicating a portion of the circle of Willis, were partly ossified. There was no evidence of the cerebral soften- ing having been produced by the presence of a clot of blood. In this case, though there was evidently very serious lesion of the brain, it was impossible, in consequence of a want of knowledge of the pre- vious history of the patient, of the mode of invasion, and of the pro- gress of the disease, to diagnosticate the precise character of the or- ganic lesion of the brain. IBITOIIMJLS,, &@, State Organization. It would be needless for us here to enter into a lengthy article on the importance and value of an organization of the profession of the whole state. We should like to publish extracts from various letters on that subject, received from subscribers in every part of the coun- try, but space will not permit it in the present Number. The interests of the physicians call loudly for an organization of some sort, and its necessity is palpable. Many different plans may be suggested and schemes concocted, but they will all be attended with some trouble and labor ; they will all fail, unless there is an united action and a good hearty co-operation on the part of all its friends, regardless of minor details. It has been suggested by several correspondents and others, that the Medical society of Virginia is an institution of the state at large, and not intended to be a local affair for the city of Richmond. It holds a valuable charter, (we published this in our last,) under which every EDITORIAL. 152 physician in the state may be enrolled, and which is amply sufficient to cover an organization of a body which could effect all the practical reform, &c. which may be achieved in any other way. Then it is plain that the simplest and most effective mode of organizing the pro- fession now, is to take advantage of that strong charter, and make the respectable physicians of the state members of the society. Let it hold annual meetings, as the American medical association does, and let the county and city societies be branches, to regulate their local matters — -while those of general interest would be the business of the general state society. Other states have acted, and without having any such advantageous medium to operate through. We are fully aware that there are some who are unwilling to give up the charter now held by the Richmond city society to the state at large and re- solve it into a branch body, with a local organization, but we are as well aware that there are some who are unwilling to do anything to- wards the accomplishment of the object, or towards anything further than to make and collect fees. We trust that these do-nothing gentle- men will turn out to be in the minority, Let the profession elsewhere in the state insist on their rights and enjoy the privilege of making their state organization under an authoritative act of assembly, al- ready passed, but now in the hands of the Richmond city physicians* We hope that Virginia will be fully represented at the next meeting of the National Medical Association, and as that body meets about the 1st of May, there is no time to be lost in making up the delegations to represent the schools, societies, and the profession at large. It is too much the custom in Virginia to appoint large delegations to all con- ventions. The effect of this is, that few, if any, ever deem it their duty to go, and the appointment passes off as an empty honor. We therefore hope, in the appointment of delegates to go to Charleston on the part of our schools and societies, that men who will go will be ap- pointed, and not those who simply desire to be recorded on the roll. We would be glad to receive correct lists and to announce them in our next Number. It may be well to state that, according to the rules of the association; societies are allowed one delegate to every ten members. A good delegation from Virginia will induce the convention of 1852 to assemble here. 152 EDITORIAL. " A Treatise on Strabismus, with a description of new instruments designed to improve the operation for its cure, &fc, illustrated by cases. By James Bolton, A. M., M. D., Memb. Med. Soc. Va., 36 pp. P. D. Bernard, Richmond.'''' We have received this little treatise from the author, and take plea- sure in recommending it to the profession, as a simple but perfect de- scription of this deformity, with the manner of procedure for its cure. With it and the simple instruments described, the merest tyro may operate with safety and success. The remarks on the cuuses, advan- tages of the operation, and the complications, are short but to the point. It is entirely a Richmond production — the writing, printing, engraving and binding — and does credit to the artists. 41 Report of a case read before the Med. Soc. East Tennessee, in which the diagnosis was disease of the Tcidney. By Frank. A. Ramsey, M. D., Cor. Sec," fyc. We have received this little brochure, " published by order of the societ}'," and perused it. It is a sort of treatise on the diagnosis of kidney disease, with a case followed up. The paper is an instructive one, but the author is rather indefinite in some points. After announc- ing the death of the patient, the author says : " It is true, no post mortem examination was made ; but with all the lights which are given us by the developments made from post mortem examination of the reported cases, we cannot ascribe our patient's symptoms to any other source than the kidneys." An examination should have been in- sisted on. We have received the Introductory Address of Dr. M. M. Pallen, Professor of Obstetrics, &c. in the St. Louis University, delivered to the class of 1S50-'51. Of course, this lecture abounds in good senti- ment and is prettily written ; but we take this occasion to remark, that throughout our whole country pathological anatomy is too much neglected. A proper estimate is not instilled into the 37oung doctors of the great value of making close and accurate post mortems when- ever an opportunity is afforded. Let us do this, and in a few 3Tears we will not have to look to Europe for all of our pathological facts. Of course we differ widely with Professor Pallen, where he sa3*s : " The undue importance attached to post mortem examinations (a valuable aid I admit) is another serious error — it leads to the neglect of correct observation during life," &c. Now, the learned professor may be very right in much that he says here, but it is at least a ques- tion of doubtful policy to underrate post mortems to a class of stu- dents, a majority of whom may never be prone to make them. They EDITORIAL. 153 ought rather to be encouraged to do it, and every means ought to be adopted to do away with the prejudice in the popular mind against them. Medical Progress, alias Fanaticism. We have received, under the frank of a M. C, a little pamphlet entitled " An Appeal to the Medical Society of Rhode Island, IN BEHALF OF WOMAN TO BE RESTORED TO HER NATURAL RIGHT AS ' MIDWIFE,' and elevated by education to be the physician of her own sex"—! ! ! " NO COPY-RIGHT," " printed for the author— 1850." Endorsed on the last outside page, is " Read and Lend," in big black letters. At the end is the following insinuating appeal : " Respected Reader, "In order to promulgate the principles of the ' mighty truth,' I am induced to publish gratuitously the above letter, which is offered for }Tour candid consideration and attention, and with the prayer that it will awaken you to a sense of moral duty to accomplish its sole object of pure benevolence. By reprinting or publishing, (by subscription or otherwise,) and freely distributing these sentiments throughout our country, you will aid the cause of morality and virtue, and may God, in His infinite goodness, reward you for your labor, is the prayer of The Author." This filthy and obscene effusion, from some whining, hypocritical fa- natic, has been very extensively circulated, we believe, throughout the whole United States, and is put into the hands of women and of he grannies. Its doctrine may work its way like priestcraft, particularly as its language is that of ranting fanaticism and popular piety. It be- gins, " With a deep sense of my duty to God, and my obligations to society ; with a trusting faith that an overruling Providence will rightly direct my efforts in the cause of humanity," (! ! !) "I wish to address you upon a subject of vital interest, and one on which you will soon be called upon to decide, by the overwhelming force of pub- lic opinion, viz: Women's Rights, in this matter," &c. !!! There are some novel facts which we learn for the first time in this grand document. One or two of the newest are these : " while every nation on the continent of Europe educate and employ women only in obstetrics. In our Southern states, the negro woman, with no other than the intuitive education of nature, always 19 154 EDITORIAL. performs this office for her white mistress with far greater safety than is possible for man. " The medical college at Geneva has done itself honor in conferring a diploma on Miss Blackwell. Mrs. Fowler and Mrs. Gleason, with degrees of M. D., are professors in the Eclectic medical college of Rochester, N. Y.; a female medical college has just been chartered by the state of Pennsylvania, at Philadelphia ; female students are ad- mitted to equal privileges in the medical colleges at Memphis and Cin- cinnati, and are about to be admited at the medical institution at Wor- cester, Massachusetts." This small potato should not have received even a notice at our hands, but for the fact of its general circulation, and our opinion that it is calculated to make as great an impression in some communities and produce as bad an effect, as a respectable practitioner could era- dicate in years. "Vive la bagatelle!" The following journals have been added to our exchange list since the last Number : The Northwestern Medical and Surgical Journal, 64 pages, bi- monthly, published at Chicago and Indianapolis, and edited by John Evans, M. D., Professor of Obstetrics, etc. in Rush Medical College, and Edwin G. Meek, A. M., M. D. The American Journal of Medical Sciences, with the Medical News and Library for January and February. The Western Medico- Chirurgical Journal, a small monthly, published at Keokuk, Iowa, and edited by Drs. J. F. Sanford and Samuel G. Armor, Professors in the Iowa University, No. V., Vol. 1, Janu- ary 1851. The Western Lancet and Hospital Reporter, Cincinnati. Edited by Professors L. M. Lawson and Mendenhall. The New York Journal of Medicine, edited by Dr. S. S. Purple, an excellent bi-monthly. The Medical Examiner for February has not yet been received. The Ohio Medical and Surgical Journal for January is received. We notice it contains the valedictory of its late editor, Dr. S. Plan- bury Smith, who has been called to take charge of the Ohio Lunatic Asylum. Dr. Richard S. Howard, who succeeds Dr. Smith in the chair of surgery in the Starling Medical College, has taken charge of the Journal, and promises in his introductory " to use every exertion to make it a good journal, and to discontinue it when it is reduced to a mere echo or reprint." From this introductory, we observe that the profession in Ohio numbers about four thousand. EDITORIAL. 155 The Buffalo Medical Journal and Monthly Review, edited by Dr. Austin Flint; February Number. The Southern Literary Messenger, of our own city, for February, is on our table. It sustains well the high character which it bears, and is certainly one of the best literary magazines published anywhere. Its only fault with Virginians is, that it does not come from abroad. We thank its able editor for his notice of us. We hope that our sub- scribers will increase sufficiently to support our work at its present cheap rate, though our experienced friend Thompson says we have started on too large a scale. To Correspondents. Communications have been received from Dr. John P. Mettauer, J. M. Gait, Richard H. Parker, J. L. Dorset and others, but they came too late for the present Number. B.'s article will appear in our next. We shall not only be pleased to hear from him frequently, but beg that he will at least give us his name. Dr. S. is informed that our pages are not the proper medium for personal wrangles between physicians. According to his statements great injustice has been done him, to be sure, but the medical society of his district is the proper place for adjusting the grievances com- plained of, and we advise the doctor, (who is no doubt a gentleman of the highest tone,) to appeal to his fellows. If there is no society in the county, then form one at the next court. Medical Society of Virginia. The last meeting (Feb. 18th) was a very full one, and we were glad to see that there were many country members and visiters pre- sent, though at the same time the State agricultural society was in session, and there were several other occurrences in the city calcu- lated to draw off members. A large number of letters of applica- tion for membership were read and laid on the table — they were mostly from physicians in the country. The subject of typhoid fever was then debated at great length, the pathology of the disease being the principal topic of each member's remarks. 156 EDITORIAL. The whole, or such part as may be ready, of the report of the committee on anaesthesia was made the subject of discussion for the next meeting, (March 18th.) An interesting debate may be expected. Dr. Bolton presented a portion of the stomach of a mare, having its mucous surface thickly studded with larvae of the bott-fly (cetrus equi.) The animal died of colic during the winter of 1849-50, having been previously in fine health. She was thorough-bred, and about 9 years old. The report of a committee to prepare a memorial to the cit}*- coun- cil for the establishment of a city dispensary was read and adopted, and the committee instructed to present it to the council. The hour being late, the society then adjourned. It may not be known to many of our readers, that every post in France, almost from that of nurse in a hospital ward up to the highest scientific honor, (member of the Academie des Sciences,) is filled by public competition or concours. This system we believe will be uni- versally adopted, unless the world takes on a retrograde action ; and as an illustration of the admirable working of the system, we clip the following From the London Medical Examiner. The Concours. A description of the late contest for the chair of operative surgery in the faculty of Paris, will explain the matter more fully. We ex- tract the particulars from the " Gazette des Hopitaux" and " L'Union Medicale." The judges were, Cruveilhier, Andral, Denonvilliers, Du- bois, Gerdy, Langier, Moreau, Roux, Velpeau, Begin, Jobert, Gi- melle, Baffos and Huguier. The candidates, Lenoir, Nelaton, Richet, Gosselin, Sanson, Robert, Maissonneuve, Jarjavay, Chassaignac and Malgaigne. Several questions are put into the urn, and the candidate has to answer that which falls to his lot. This examination consisted of five proofs. 1. A written dissertation, (drawn by lot,) the subject the same for all the candidates. 2. A lecture, after three hours pre- paration. 3. A second lecture, after twenty-four hours preparation. 4. One or more operations on the dead body. 5. A thesis, upon which each candidate is examined by his competitors. The relative value of the different modes of union, after surgical operations, formed the subject of the first trial. The remaining questions were as fol- low : On the different methods of arresting haemorrhage after opera- tions ; subcutaneous sections ; the use of the trephine ; operations applicable to the treatment of erectile tumors; on amputation and ex- tirpation of tumors in general ; on amputation of the limbs ; opera- tions for non-united fractures ; operations for varicose veins ; of arti- cular resections in general ; operations on the iris ; operations for SELECTIONS. 157 aneurism of the carotids ; on strangulated femoral hernia; on punc- ture of the bladder; operation for the restoration of the eyelids. Three operations on the dead body were performed by each of the candidates. The numbers were, first "tour," Malgaigne 8, Robert 4, Nelaton 2, Lenoir 1, Jarjavay 1. Second "tour," Malgaigne 8, Robert 4, Nela- ton 3. The election of Malgaigne must be hailed by all with satis- faction. This mode of decision cannot invariably insure a just selec- tion, but an incompetent candidate can never succeed. Results of Fifteen Operations for Lithotomy. BY P. C. SPENCER, M. D., OF PETERSBURG, VIRGINIA. In the following operations, performed within the last fifteen years, in Petersburg, Va., the instrument used was the lithotome cache, or the bilateral improved instrument of Baron Dupuytren. Case I. — A free boy, four years of age, was operated on in Sep- tember 1833. Drs. Theophilus F. Gilliam and Birchett were present. From some unknown cause he died in the course of the night. His parents refusing positively to allow any kind of examination to be made, and as the loss of blood was very inconsiderable, and nothing unusual occurred in the operation, we were totally at a loss how to account for his death, unless it was from a nervous shock given to the system. The calculus extracted was about the size of a pigeon's egg. Case II. — Mr. Edward Ragsdale, of Virginia, aged seventeen years, was operated on October 1st, 1835. Drs. L. White, of Petersburg, and Morrison, of Brunswick county, assisted in this operation. We found a very large calculus encysted a little behind and laterally to the pros- tate gland, and so completely imbedded as to require considerable force to separate it from the wall of the bladder. This operation was performed about fifty miles out of town, and I was unable to see the patient as often as I wished. For a few days after the operation the case appeared as though it would do well. Later, however, he fell back, and steadily declined, and died on the fourteenth day. This result was not altogether unexpected, and was attributed to the great delay on the part of the patient in assenting to the operation, his weak condition, and the severity of the cystic irrita- tion, which had so long existed ; for he would only submit to the knife in the last extremity. Case III. — A slave, aged thirty-five years, operated on in May 1837. After the result of the two previous cases, I invariably placed the patient under preparatory treatment, varying the treatment accord- ing to the circumstances, and witnessed the happiest results. In this operation I was assisted by Dr. L. White and several students of medicine. We removed a very large calculus. The patient passed his urine naturally on the eighth day, had no fever of consequence, was walking about on the twentieth day, and in the course of a month returned home cured. 158 SELECTIONS. Case IV. — A slave, aged eighteen years, was operated on May 16th, 1837. In this operation I was assisted by Dr. L. White. We removed a very large number of calculi, which we found this bladder contained, many of which were so fragile that they were broken to pieces in attempting to bring them away. This patient, much to my astonishment, but more to my pleasure, passed his urine naturally on the fifteenth day, had no fever of consequence, but little after treat- ment, and returned home about the fortieth day cured. Case V. — J. L. Long, of Virginia, aged seven years, was operated on November 21st, 1838. I was assisted in this operation by Drs. L. White, Cox, Michie, and several students of medicine. We removed a calculus of medium size. On the fifth day he passed his urine natu- rally. His recovery was rapid, and he returned home on the twenty- fifth day cured. Case VI. — Ripley Maggett, of Virginia, aged nine years, was ope- rated on in May 1S39. Drs. Robinson, White and Jones assisted in this operation. I made an opening into the rectum, and found it ex- ceedingly difficult to effect a union of the parts. The only remedy resorted to was the solid stick of lunar caustic, introduced into the rectum on the finger of the left hand ; an operation which I found ne- cessary to be exactly repeated every thirty-six hours, for if I waited forty hours, his evacuations would pass through the cut, sometimes fasces and urine commingled. The after treatment was more pro- tracted than in any previous case. He returned home in about forty days, but with occasionally some moisture of the parts. He finally recovered, and his health has been perfectly restored. Case VII. — Slave Ambrose, aged five years, was operated on June 1st, 1840. Drs. White, Michie and Jones assisted in this ope- ration. We removed a calculus of more than ordinary size. He passed his urine naturally on the tenth day, and on the thirtieth re- turned home cured. Nothing unusual occurred in the case. Case VIII. — James Wells, of Virginia, aged four years, was ope- rated on in September 1844. In this operation I was assisted by Drs. White, Jones and Couch. He passed his urine naturally on the eighth day, was walking about on the fifteenth, and returned home cured on the thirtieth day. Case IX. — Mr. H. Hardy, of North Carolina, aged eighteen years, was operated on November 21st, 1844. The necessary preparatory treatment was administered by Drs. Johnson and Cross, of the neigh- borhood, when I visited him, attended by my friend Dr. J. F. Peebles, who assisted, in conjunction with the two gentlemen above named, in the operation. We removed an uncommonly large calculus. Although the operation was performed with our usual caution, and in the same manner as heretofore, yet the pudic artery was unfortunately wounded. It is perhaps worthy of remark that this accident did not at once mani- fest itself. It was only after the patient had been cleansed and re- placed in bed that haemorrhage came on. After, in quick succession, he had discharged several coagula of blood of the full size and shape of the bladder, which he voided, impelled by a desire to urinate, symp- toms of sinking to such an alarming extent came on that it became necessary to replace him once more on the table, with the view of SELECTIONS. 159 arresting the haemorrhage. Whilst preparing a tent for this purpose, Dr. C. Cross inserted his finger into the wound, and feeling the jet of blood impinging against it, suddenly made pressure on the spot. The manoeuvre was eminently successful. It was soon found that he had the bleeding entirely under control. Other measures were at once abandoned for this simple yet direct procedure. With unflagging zeal, altogether above all praise, Dr. C, despite the discomfort of his position, steadily maintained the pressure on the wounded vessel for five or six hours, when, gradually withdrawing his hand, we found that all bleeding had ceased. A sponge was then introduced on a canula, which was saturated with a solution of creosote, and allowed to remain until suppuration took place. The weak state of the patient, combined with much cystic irritation, which continued for some time, rendered his condition extremely pre- carious for several weeks. Under appropriate local and general treat- ment, however, he gradually gained and finally was perfectly re- established in health. Case X. — Mr, J. R. Lunsford, of Virginia, aged twenty-seven years, was operated on January 17th, 1845. Drs. White, Jones, Couch and Strachan aided in this operation. We removed two calculi, one of more than ordinary size, lying just in front of the prostate gland, the other in the bladder. Finding two, either over the common size, I examined very minutely with the finger and the instruments, but found no other. I then proceeded to wash out the bladder with warm water and Castile soap, and replaced him in bed. He rallied at once, and was restored to complete health in an unusually short time. He passed his urine naturally on the tenth day, and returned home on the twenty-fifth day. Case XL — Master Rufus Stallings, of North Carolina, aged four years, was operated on May 18th, 1847. I was assisted in this ope- ration by Drs. J. F. Peebles, White, and Thweatt. The calculus was removed, and he commenced passing his urine naturally the next morning. On the third day he passed all his urine per urethra, and returned to the interior of North Carolina on the nineteenth day from the operation, in fine health and condition. Case XII. — Cornelius, a slave, four years of age, was operated on May 31st, 1848. Drs. Peebles, White, Withers, and Thweatt as- sisted in this operation. The calculus was removed, and he com- menced passing his urine naturally on the fifth day, recovered his health rapidly, and returned home on the twenty-fifth day well. Case XIII. — Master Louis Blitz, of Virginia, aged seven years, was operated on March 25th, 1849. I was aided in this operation by Drs. White, Michie, Couch and Hinton. We removed rather a small calculus. The health of this patient was extremely low, and his re- covery gradual until the tenth day, when he commenced passing his urine naturally; from that time he recovered rapidly, and- returned home on the thirtieth day from the operation in good health. Case XIV. — William, a slave from Williamsburg, Virginia, aged four years, was operated on April 29th, 1S49. In this operation I was assisted by Drs. Peebles, Michie, Withers, Couch and Durkin. We removed an uncommonly large calculus from the bladder, mea- 160 SELECTIONS. suring one and a half inch in length, and large in proportion. The little boy had suffered from birth, and had become so much emaciated and relaxed as to render the operation most difficult. After the first cut of the scalpel, such immense relaxation and prostration of the lin- ing membrane of the rectum took place, that I was compelled to lay the bistoury down frequently to replace the protruded membrane be- fore I could complete the necessary section to get in the groove of the staff. In the progress of the operation, I unavoidably cut into the rectum, as I apprehended. Having committed the same error in the sixth case, or operation on R. Maggett, I at first feared much trouble, but suggested to my friend Dr. Peebles the propriety of locking up the bowels, with some preparation of opium, and permit the small open- ing in the rectum to heal as speedily as possible. To our astonish- ment and gratification, in a few days the part had healed and become firm, and on the fourth day he passed his urine naturally. Recovery in this case was as speedy as in any I had ever known. On the twenty-second day from the operation he returned to his home in Wil- liamsburg, full of life and health. The above mode of treatment I have since ascertained, first sug- gested, 1 believe, by M. Chomel, of Paris, is now generally employed in cases of intestinal perforation occurring in typhoid fever. It is cer- tainly applicable to all cases of wounded intestines, and I perceive that Dr. Gerhard also recommends it in pneumothorax. Case XV. — Mr. A. Wells, of Virginia, aged twenty-eight jTears, was operated on September 23d, 1849. I was assisted in this opera- tion by Drs. Couch, Peebles, Hinton and Rives. We removed a cal- culus weighing five hundred and sixty-three grains. The enormous size of the stone considered, it was with no little surprise and pleasure that we found him passing his urine naturally on the eleventh day. His general health improved rapidly, and the only after treatment pur- sued was the infusion of buchu through the day and a good and nour- ishing diet. It may be proper to remark here, that the external inci- sion did not heal as rapidly as we anticipated. The healing process was very gradual, and it was not until the caustic had been several times applied that we could get the part to heal completely. Recapitulation of the Fifteen Cases. 1st case died in the course of 12 hours. 2d do. " " " " 14 days. 3d do. urinated naturally on the 8th day. 4th do. " " " 15th day. 5th do. " " " 5th day. 7th do. " " " 10th day. 8th do. " " " 8th day. 10th do. " " " 10th day. 11th do. " " " 3d day. 12th do. '• " " 5th day. 13th do. " « " 10th day. 14th do. " " "4th day. 15th do. " " " 11th day. SELECTIONS. 101 In the 6th and 14th cases the rectum was cut. In the 9th case the pudic artery was divided. Of the 15 cases, 9 were whites, all males; 3 boys, 4 nearly grown, and 2 over 21 years of age. The number of blacks 6, 4 boys and 2 men. — American Journal of Medical Sciences. [Case XVI. — The boy Austin, a slave, aged 17 years, having la- bored for years under a painful affection of the bladder and urethra penis, as was supposed by some of the profession, was, on the 26th February 1850, ordered to this place, to have an examination made. It was supposed, from the general history of the case, that a calculus of ordinary size was contained in the bladder. The introduction of the sound shewed this to be true — and after the necessary preparatory treatment, the operation was performed, March 3d, 1850, Drs. Peebles, White and Cox being present. We removed a calculus weighing 630 grains. I think it extremely probable that more than one opening was made into the rectum, owing to the ungovernable character of the sub- ject, the difficulty of managing him being greater than in any former case. On the third day, I found the urine passing off with the faecal evacuations — and to remedy it, gave the opiates a fair trial. They were ineffectual. In this case sloughing of the celular tissue was very extensive. After the use of the opiates the stick caustic was resorted to — it being applied every 36 hours, was also ineffectual. Recovery being slow, it seemed important that the improvement of his general health should be looked to. To accomplish this, a more generous diet, in combination with quinine and camphor, moderate exercise, and longer intervals for sleep and quiet, were recommended. These acted like a charm. On the 22d May he returned home, and very soon en- joyed complete health. He has not been heard from since November last ; he was then well and growing rapidly ; he no doubt continues well, or he would have been heard from, as he lives only a few miles out. — p. c. s.] Attending Families by the Year. — The plan of attending families by the year is dictated by a trading, mercenary spirit, un- worthy of members of a dignified profession. It has too much the air of pelf about it, and should at once be abandoned. It may suit the dealer in matches, the butcher or the iceman, but is clearly out of place among physicians. We are glad to hear that, notwithstanding the efforts of some members to have it recognised by the Medical society, that respectable body unhesitatingly condemned it. — St. Louis Probe. [We cordially concur in the sentiment here expressed. In Rich- mond (and throughout the state, we believe,) the practice has long since been scorned down. If there are any exceptions, the low tradesmen in the profession who practise it are beyond the pale of respectability, or conceal their names even from the public. — Ed.~\ 162 SELECTIONS. Case of Communication letween the Stomach and External Surface of the Abdomen. — In the last number of the Edinburgh Monthly Journal of Medical Science, is a paper by Dr. William Robertson, one of the editors, upon the case of a woman who has a communication between the stomach and external surface of the abdomen. The great simila- rity between this patient and Dr. Beaumont's, Alexis St. Martin, who was the subject of many experiments in this country, some years since, has induced the Medico-Chirurgical society of Edinburgh to make si- milar observations and experiments upon her, so far as may seem compatible with her welfare. The committee to whom is entrusted the examination, consists of Drs. Christison, Bennett, Maclagan and Robertson, with Messrs. Syme and Goodsir. We have no doubt that this committee, which consists of gentlemen eminent in medical litera- ture and science, will make many interesting observations in the phy- siology of digestion, which the modern researches on that subject would seem to render very desirable. This opening into the stomach is attributed by Dr. Robertson to a chronic ulcer in its cavity, which occasioned, " whether by perforation or otherwise, extension of inflam- mation to a limited portion of its external surface, and consequent ad- hesion to the abdominal parietes — that thereafter an abscess formed external to the stomach, and discharged its contents into the viscus — that the contents of the stomach, acting upon the walls of the abscess, ultimately caused the ulceration of the integuments." — Boston Med. and Surg. Journ. Vaginal Speculum. — Mr. Haslam of Harvard Place, Boston, is the inventor and manufacturer of an improved vaginal speculum. It is made of glass, and silvered on the outside ; the silvering being co- vered over by gutta percha, makes it, of course, perfectly safe. The inside of the tube is a perfect mirror, and will reflect the light better than a metallic one ; besides, there cannot be any danger of corrosion, either by the secretions or the substances used in medication. This speculum has been used by many of our best physicians for a year or two past, and has given the greatest satisfaction. Since the first ones were manufactured, the proprietor has made improvements upon them, in form, size and covering, but can still afford them at prices extremely moderate. — Boston Med. and Surg. Journ. [We know this excellent speculum of old, as Dr. Simpson's of Edin- burgh.— Ed.~\ In the 39th No. of the American Journal of Medical Sciences, Prof. Bigelow of Boston has made a complete record of the history of one of the most unparalleled cases in the annals of surgery. It is the case of recovery after the passage of an iron crowbar through the skull, carrying away with it much of the substance of the brain. This case occurred in the practice of Dr. Harlow of Vermont, in SELECTIONS. 163 September 1848, and full details of it and the present healthy condi- tion of the patient are given in the journal above referred to, where the curious or skeptical may satisfy themselves of the authenticity of the report, and of all the circumstances. As portions of the brain to which are allotted different functions, passions, &c, were entirely de- stroyed, phrenology would teach that these functions would be entirely annihilated. This, however, was not the case, for " the man was still able to walk off, and talked with composure and equanimity of the hole in his head," and has never been, up to this time, other than a rational man, save for a short period at an interval of about a fortnight after the accident. A New Propei'ty of Chloroform. — Academy of Sciences, Paris, Nov. 11, 1850. — M. Augend of Constantinople, transmitted a memoir, in which he pointed out a property that places a very distinct line of de- marcation between chloroform and ether ; this is, its power of disin- fecting organic matters. M. Augend related the following experi- ment : Take three wide-mouthed flasks, the first containing a few drops of ether, the second a few drops of chloroform, the third left empty. If in each of these a piece of beef be placed, and the flasks be closed and left undisturbed in the summer season, the following circum- stances wTill be observed : The meat, which was of a reddish brown color in its natural state, changed instantly to a vermilion-red in the mixture of chloroform and air, while in the ether vapor no change oc- curred. At the end of a week the difference was greater still ; the meat in the flask containing atmospheric air was but little changed in its aspect ; that in chloroform had acquired the appearance of boiled meat. On opening the flasks it was found that the meat, both in the atmospheric air and in the ether vapor, was putrefied, and emitted a most offensive odor ; while that in the mixture of chloroform and air had the sweetish taste and odor of chloroform. M. Augend has ascertained that Tooth of chloroform completely prevents the putrefaction of fresh meat. The most apparent action of the chloroform is the rapidity with which it traverses the thickest tissues, and causes an immediate contraction of their parenchyma, with consequent exudation of the fluids of the structure experimented upon. The author further dwelt upon the value, in a medico-legal point of view, that chloroform thus possesses in arresting putrefaction. [_Med. Gaz. Medical College Circulars. — Does not the honor of the j)rofession call for a reform in relation to the spirit and tone of these circulars? Read the following from one of the fraternity — the editor of the West- ern Lancet : " We wish to call the attention of our friends, the pro- fessors of medical colleges, and also the editors of medical journals, to the style of commendation which has for the last few years crept into the circulars of our medical schools. It is not necessary to al~ 164 SELECTIONS. lude to the origin of this practice, or to designate one college more than another, for all are more or less implicated in it. It appears to us that the style of these documents might be much improved, and made to conform more to professional propriety than they do at pre- sent, with advantage. We see no reason why a body of men, col- lectively, ought to say that about themselves, that would be impro- per for any one to say about himself as an individual. Professional etiquette and propriety prohibit puffing and laudatory notices of one's self'l Ought it not to be equally binding on an association of medical men ? We have thrown out these few thoughts without intending to cast censure, but for reflection ; if we are wrong, we do not object to being set right." We may, in a future number, say something on the character and tendency of these annual productions. — [N. Y. Jour, of Med. Cod-Liver Oil in Phthisis. — M. Duclos thus sums up the results of his experience with this substance : 1. The presence of fever is what we must chiefly attend to, relying more on this remedy when it is absent and less when it is present. 2. The remed}^ frequently arrests the progress of the disease when only in the first stage. 3. It rarely arrests it when in the second stage, although it may retard it. 4. The third stage is not favorably influenced by the oil. 5. The oil should be administered for a considerable time, and, if a good effect results, it should be suspended awhile, to be' again resumed. Thus, it may be given for two months and then suspended for a fortnight, resumed for a month and re-suspended for a fortnight again, so as gradually to reduce the length of the intervals during which it is given. 6. The clear, slightly smelling, nearly tasteless oil, is less efficacious than the brown, thick, strong oil. — Brit, fy For. Med.-Chirurg. Rev., Oct. 1850, from Bulletin de Therapeutique, xxxviii. On the best manner of administering Iodine — Use of Iodide of Starch. BY DR. QUESNEVILLE. The interesting memoir lately published by M. Chatin should at- tract the attention of medical men to the important part that iodine plays in medicine. According to M. Chatin, in fact, iodine is to be found in nearly all soft waters ; it exists in plants, in terrestrial ani- mals, in fermented liquors, wine, cider, perry, in milk and in eggs. It forms a part of arable earth, and its presence, in a word, is almost universal in all the aliments used by man. When iodine is absent from the waters of certain springs and of cer- tain countries, it is remarked in these countries that the inhabitants are more unhealthy and have a peculiar predisposition to scrofula and goitre. The water from wells, always so unwholesome, does not con- tain nearly as much iodine as soft water, and the water proceeding SELECTIONS. 165 from the liquefaction of snow is totally without it. These observa- tions, supported by between five and six hundred analyses, are most important, and should be taken into serious consideration by medical practitioners. Reflecting on all these facts, we asked ourselves under what form iodine could be administered in medicine ; we then remembered that many years ago we recommended the use of soluble iodide of starch to some scrofulous patients, and that the cure had been remarkably prompt. Combined with a body like starch, so easily assimilated with the other digestive principles, iodine is liberated immediately on its arri- val in the stomach, and thus disengaged from its combination. It then acts as iodine would act were it administered in the pure state and not combined with alkalis or metals which cause the loss of a portion of its virtue. M. Huette proposes the use of hydriodic ether, which he advises to be inhaled by the patients. This means is without doubt most inge- nious, and may render great services in certain exceptional cases. Whilst trying to reproduce soluble iodide of starch, we remarked that sugar heated for some time with the iodide of starch, precipitated as a paste, combined with it perfectly, and that the syrup which is ob- tained from it was of a very deep blue color and perfectly transpa- rent ; this, then, will enable us to prepare a syrup with the iodide of starch. Wishing to know in what proportions this syrup of iodide of starch can be prepared, we have made it ourselves, and have obtained the proportions of 12 grammes of iodide of starch to 1 kilogramme of sy- rup, which represents, according to the composition of iodide of starch, 5 grammes of iodine to each kilogramme, or £ per cent. When it is wished to give iodine in small doses, to order it for children for exam- ple, to susceptible systems, or to stomachs already irritated, nothing can be better than the soluble iodide of starch. It thus replaces suc- cessfully the cod-liver and skate-liver oils. In giving large doses of iodine, as the syrup, if taken in too great quantity, becomes disagree- able, it can be replaced by powder of iodide of starch, which can be given like rhubarb, made into pills or simply mixed in water. These powders contain, combined with an excess of starch, 10 per cent, of iodine ; they are perfectly washed in boiling alcohol in order to deprive them of all excess of iodine which would be dangerous. Iodide of starch can be taken in very strong doses without irritating the stomach or intestines ; it acts much more readily than the other compounds of iodine, and should be preferred to them in most cases, [Revue Seientifique. Re-Vaccination in Prussia. — Re-vaccination is systematically practised in Prussia. No child is admitted into a school without proof of vaccination, and every recruit is vaccinated on admission into the army. In the year 1848, 28,859 soldiers were vaccinated ; of these, the vaccine disease was regular in 16,882 ; in 4,404 indi- viduals it was irregularly developed, and in 7,573 it did not take any effect. — London Medical Gazette. 166 SELECTIONS. Poisoning with Hemlock. BY DR. BOUCHARDAT. Cases of poisoning with hemlock are rare. I have lately had occa- sion to observe an instance at the Hotel-Dieu. A young woman had, in a moment of desperation, as she said afterwards, swallowed a strong dose of the juice of hemlock, which she had herself prepared, being aware of the poisonous qualities of this plant. When brought to the hospital, she was unconscious. The only guide I could obtain was this — " This woman has knowingly poisoned her- self with a plant, which she gathered in the neighborhood of Meudon." The eyelids were firmly closed ; force was necessary to open them ; it was then clearly perceived that the pupils were dilated ; respira- tion, though weak, was performed in a satisfactory manner ; ,the pulse was small and 82. The skin, although not icy, was cold ; some slight spasmodic movements were to be remarked in the superior members as well as in the muscles of the face. I thought that an hysterical attack complicated the effects of the poison. I suspected stramonium, or other poisonous solanum, digita- lis or hemlock. In this dubious state, it was certain that the best course would be to cause vomiting, and then, by examining the mat- ters expelled from the stomach, to ascertain the nature of the poison which had been taken. Fearing a decomposition of the emetic, I pre- scribed a mixture of 1£ gramme of ipecacuanha in powder, and 15 centigrammes of tartar emetic, in three doses, to be administered at thrice with five minutes interval. The emetic draught acted thoroughly, the patient vomiting several quarts ; the liquid thrown up was slightly green ; but after these vo- mitings she seemed to be going on so well, that I thought it better to wait before prescribing anything further. The improvement was so rapid, that by the evening she was nearly well; and the next day she felt no farther inconvenience from it. — Repertoire de Pharmacie, Au- gust 1850. On the danger of tying up the Lower Jaw immediately after supposed death. BY C. J. B. ALDIS, M. D., Fellow of the Royal College of Physicians, and Lecturer on Medicine at the Hunterian School. Various well known practices are resorted to by the public imme- diately after the supposed death of their relatives or friends, such as placing shillings on the eyelids, a plate containing salt on the abdo- men, touching the body, closing the nostrils, and tying up the lower jaw. Some of these peculiarities are harmless enough ; but the two latter may be the means of destroying life, either wilfully or through ignorance. C — — , an infant, aged two months, was brought to me at the Lon- SELECTIONS. 167 don dispensary, on a Friday, a short time since, by its mother. It became atrophied soon after birth, and continued in that state for two months. The mother having taken away the child, returned with it in a few minutes, told me that it was dead, and asked for a certificate. I examined the neck, and found the lower jaw tied up so tightly, as to prevent its being moved. I immediately set the jaw free, and asked why she had fastened it up so quickly. She replied that a woman at the dispensary seeing the jaw fall, and thinking the child was dead, had done it up. I declined giving a certificate then, but kept the mother in conversation for a minute or two, in order to see if any change took place in the countenance of the child, when the right eyelid began to move, and soon after the infant was restored to its usual state, and did not die until the following Monday. It is very probable that the child would have been destroyed on the Friday had I left the dispensary before the mother's return ; and it is also probable that in another case, with more stamina in the consti- tution, life might have been preserved for a longer period. It is true that air would gain access to the lungs through the nostrils, though the mouth be firmly closed, but not sufficient to keep a very weakly child long alive, especially when we consider the pressure frequently made against the larynx on binding up the lower jaw, and the effort required to fill the lungs with sufficient air merely through the nostrils. Is it not, then, obvious that the public should wait until a medical man has seen the body, or at least for a few hours after death, without pre- cipitately tying the lower jaw, and incurring the risk of committing murder ? — Lancet. Complete Ahsence of the Anus and Rectum. — M. Forget lately pub- lished in U Union Medicate the case of a child which thirty-six hours after birth had not passed any meconium. In place of the anal orifice, there was an elastic piece of skin which did not yield a sense of fluctuation. M. Forget, though he suspected an absence of the rectum, thrust a small trocar into the pouch, but brought away a few drops of blood only ; he continued to search for the rectum with a straight bistoury, but found no such gut, though his knife was fairly in the pelvis. M. Forget proposed to the parents an artificial anus in the iliac fossa, but this was obstinately refused, and the child sent to nurse into the country, where it died, amidst homble suffering, without having passed any motions. On a post mortem examination the descending colon was found to end in a blind pouch opposite the lumbo-sacral articulation, and from this bag a fibrous cord, representing the rectum, was proceeding through the pelvis to the septum across the anus, holding the same re- lations to the surrounding parts as the rectum would have done. M. Forget mentions four cases, where both rectum and anus were want- ing; they are respectively related by Ruysch, Binninger and Jamie- son. The author infers from this case that surgeons should search for the rectum with much caution, when called upon to remedy an anal malformation. — Lancet. 168 SELECTIONS. [A case somewhat similar to the preceding has been related to us by Dr. Boaz, we believe, of Albemarle county, Va. As well as we re- member the description, the rectum was only a small tube resembling an ureter, and terminating in the vagina of the infant. The child died, and we believe a dissection was made. Will Dr. B. be good enough to write out a description of it? — Ed.] On Phospkenic Phenomena. — M. Serres (of Alais) lately addressed a paper to the Academy of Sciences of Paris, in which he endeavors to shew that the luminous impressions excited in and around the eye by pressure in the neighborhood of the organ, and called phosphen, might be rendered useful in ophthalmology, as a diagnostic sign, in those diseases of the eye where it is of importance to ascertain the state of the retina, and the degree of paralysis which it has suffered. After more than one thousand trials, the author has found that the lu- minous circle has always been produced when the pressure has been applied on the nasal side of the eye ; and when, after several days trial, no annular light is thereby excited within the eye, it may confi- dently be concluded that the retina is paralyzed, and that any opera- tions performed on the cornea, the iris, or the lens, would have no good results. Observations on the Emmenagogue Properties of Polygala Senega. BY CASPAR MORRIS, M. D., OF PHILADELPHIA. Among the articles contributed to the materia medica by our own country, not one is more important than the polygala senega. How- ever little its virtues may be esteemed abroad, there are few American physicians who do not recognize its importance in the treatment of certain stages of croup and bronchitis. My present object, however, is not to celebrate its praises in affections in which its value is so generally appreciated, but to draw attention to its effects in a class of cases which often baffle the efforts of the physician and cause no little anxiety to the patient — to properties which, though recognized be- fore, have been overlooked or forgotten. It is now more than twenty years since my attention was first directed to the emmenagogue pro- perties of this root. I cannot recall the source from whence the knowledge of its virtues was derived, but am disposed to ascribe it to the teaching of Professor Chapman, as I find on reference to his work on therapeutics, that he speaks of them in very strong terms of com- mendation, and gives the credit of first drawing the attention of the profession to them to the late Dr. Joseph Hartshorn. At the period to which I refer, I was induced to direct the employment of the senega for an unmarried lady, of about thirty years of age, suffering from sup- SELECTION?. 169 pression of the menstrual discharge of several months duration, com- bined with a catarrhal affection. So prompt was the restoration of the uterine discharge, that I considered it a mere coincidence, and re- marked it as one of those cases of facts which may be misapplied so as to teach error instead of truth. Since then I have had ample op- portunity to verify its claims to the credit of the result. The tendency of its influence to the sexual and urinary organs has often since arrested my attention, in cases of children to whom I have given it for croup, in which I have found difficult micturition follow its use, sometimes to a degree quite inconvenient. Pereira mentions among its physiological effects, "increased secretion of urine and feel- ing of heat in the urinary passages," and adds, "it appears to excite moderately the vascular system, to promote the secretions (at least those of the kidneys and skin, uterus and bronchial membrane) and to exert a specific influence over the nervous system ;" he mentions the fact that "it has been used as an emmenagogue in amenorrhosa." In the Dispensatory of Wood and Bache there is a mere casual allusion to its having been recommended in amenorrhcea ; while Dr. Eberle refuses credence to the assertion that it possesses any emmenagogue properties. The strong testimony of Dr. Chapman deserves to be disseminated anew, as it may be overlooked among the many modern works on materia medica and pharmacy. I shall therefore furnish it for the benefit of your readers. He introduces it first on the list of emmenagogues in the following terms: — " To Dr. Hartshorn of this city, we owe the credit of having dis- covered the properties of this article as an emmenagogue. Conversing with him some years ago on the difficulty of managing certain forms of amenorrhcea by the common treatment, he told me that he thought he had used it with advantage in these cases. Confiding in the accu- racy of his observations, I determined to lose no time in making trial of the medicine. This I have done since, both in my public and pri- vate practice, to a considerable extent, and with sufficient success to warrant me in recommending it as one of the .most active, certain, and valuable of the emmenagogues. It may be used either in powder or decoction, though I prefer the latter mode. My rule in the adminis- tration of the medicine, is, to direct about four ounces of the decoction, more or less, during the day, according to the circumstances of the case. But at the same time when menstrual effort is expected to be made, and till the discharge is actually induced, I increase the dose as far as the stomach will allow, having given sometimes as much as two ounces every hour. In the interval of the menstrual periods, I lay aside the medicine for a week or two, as without these intermis- sions, if it does not lose its power, it becomes disgusting to the patient." Dr. Chapman directs the decoction to be made by putting one ounce of the bruised root in a pint of boiling water, in a covered ves- sel, and reducing it one-third by slowly simmering; and recommends that its nauseating tendency should be averted by the addition of an aromatic bitter. I have not found my patients able to bear so large doses as those indicated by Dr. C, and have been wont to add liquor- 20 170 SELECTIONS. ice root, which disguises the peculiar taste of the senega, and continue the process until it is reduced to one-half. A tablespoonful three times daily of this strength, is generally tolerated without difficult}''. My habit is, when I can determine the period at which the natural ten- dency to the discharge will occur, to give the medicine in these doses for a fortnight before ; and then, as Dr. C. advises, I have suspended it until the same period is again approaching. The causes of interrup- tion to the menstrual discharge, being various, it is of course impossible to find any remedy which will meet every case. Where it depends on debility, or accompanies an anemic state of the system, other remedies than senega are more appropriate, or should be conjoined with it. Iron, aloes and myrrh, in combination, form an excellent remedy in such cases. The senega is appropriate to those cases where the sup- pression has been caused by improper exposure, and to those very frequent instances in which there is but little disturbance of the gene- ral health. Every practitioner in our large cities must have had his attention arrested by the numerous calls for advice on account of obstruction, on the part of newly arrived immigrants ; who complain of headach, and miserable general feelings, with swelling of their lower extremities. To what cause we are to ascribe the interruption of the natural func- tions under such circumstances, it is difficult to say. The same result has been noticed in the cases of young women coming from the country to Paris. It is not, therefore, due to any impression made by the sea atmosphere, but, very probably, is caused in both cases by a less nutritious diet than has been customary and the confinement in a vitiated atmosphere. In those cases in which hemorrhoids, or an irritable condition of the lower bowrels, prohibit the resort to the formulae into which aloes so generally enter, the senega may be resorted to with benefit, and also, when there is a diseased state of the ovaries or uterus itself. I have not tried it in cases of dysmenorrhoea, with scanty secretion, but be- lieve it will be found a very admirable remedy for these cases, which are so distressing to the habitual sufferer, and vexatious to the physi- cian. I shall certainly take an early opportunity to test its powers, combined with some of the narcotic extracts. Hellebore and hyoscy- amus have been the agents on which I have heretofore relied, with a good degree of satisfaction ; and the senega appears to me to partake of the same character as the hellebore, without that tendency to purge, which is often displayed by the hellebore when given in full doses. I am aware that some of our best teachers are disposed to dei:ry the existence of a class of remedies having a specific tendency to promote the menstrual flow, and rely on general treatment for the restoration of this function when suspended. This is, perhaps, a natural reaction from the disposition to rely on specific remedies in all cases. Either extreme is unsound. We may not disregard the state of the general health, but must adapt our specific means to meet special indications. I know of no reason to doubt the tendency of certain remedies to pro- duce an action on the uterus in its unimpregnated state which would not lie with equal force against the action of calomel on the liver and salivary glands, or ergot on the same organ at the time of parturition. SELECTIONS. 171 Mesmerism. There are certain things on which there must always be difference of opinion, because they do not come within the range of true science. Some persons, for instance, believe in ghosts, haunted houses, and all such phenomena ; but it by no means follows that they are therefore to be quarrelled with, for we hold that one man's opinion is as good as another's, until proved to be erroneous. Were mesmerism confined to non-professional persons, it would not engage our attention, or be more worthy our notice as promoters of science, than the belief in ghost stories ; and it is only because a few deluded medical men and others have striven to make it appear a valuable department of medi- cal knowledge, that we ever take up the matter at all. Neither is it with any fear of mesmerism proving so popular as to call for a profes- sorship in any of our universities : our sole object is, to remove the dis- grace which has necessarily been brought upon our high and noble profession by the manner in which some ardent imaginations have thrust it forward as an important branch of the healing art. Admitting that all the marvellous stories of its promoters were true, admitting that it were even possible to raise the dead by its means, how could its most zealous acfvocates prove the adequacy of the means to the result ? What room for science in the matter at all? There could certainly be the miracle staring them in the face, but there would be no scientific elucidation of the matter. Let not our readers suppose we believe such things. We are taking the mesmer- ists on their highest ground. During the many years the public ear has been abused with it, they have not given any pathological or physiological proofs. Were any one of our brethren to say of chlo- roform, or ether, that the effects which followed were owing to spiritual agency, we should at once tell him he had not made himself acquainted with the science he professed ; for it is easy to prove that the conse- quences produced by chloroform are dependent upon the physical ac- tion of chloroform itself. Mesmerism admits of no such proofs. But if men honestly come forward and say that there is something in it which they cannot explain, they are welcome to their belief in it, as freely as to their belief in any other nursery tale. But we reiterate our protest against mixing up the subject with the medical art, and we will never rest until it has been exterminated from a profession which ought to be devoting itself to higher and nobler aims. As we have before stated, we are not finding fault with any man for his peculiar notions ; but among other things on which we have set our hearts, is the crushing of quackery in each and all its detestable forms: and quackery is not confined to advertising specifics for incu- rable maladies. Legerdemain, under the disguise of the words animal magnetism, is the vilest quackery of all. If, as some of our corres- pondents affirm, the power exercised be spiritual, then, for heaven's sake ! let us leave it for those whose peculiar province it is to deal with such. If, on the other hand, it can be proved to depend upon a magnetic fluid, we shall be happy to give the subject our best con- 172 SELECTIONS. sideration. Our only surprise is, that this wonderful fluid is not to be had long before this, at the patent medicine venders, in little bottles Is. l%d. each, for we are persuaded this is all that is needed to crown the delusion. Again : if its advocates only pretend to state that cer- tain results follow certain manipulations, they state nothing more than has been affirmed from time immemorial ; but what in the name of common sense has this to do with animal magnetism, or how does it prove that there is such an extraordinary fluid in any animal ? We wish our readers distinctly to understand that we are not attacking individuals in their private capacities ; we are composing a compara- tively small number of medical men, in their character as members of a body politic, upon which they have brought dishonor. We, as private individuals, may have many opinions peculiarly our own, not only on the subject of mesmerism, but on insanity, catalepsy, &c, all of which might be strongly expressed were our journal a miscella- neous one; but to devote its columns to such purposes would be to render ourselves guilty of the very thing we condemn. As journalists we treat of facts and reasonings in science and literature ; all without the range of these we consider quackery, and mesmerism pre-emi- nently so. — London Institute. Medical Organization. We were struck, on reading the recent address of the king of Prus- sia to the Prussian chambers, with the circumstance that the policy and organization of the medical profession was referred to as one of the great questions of national welfare to be discussed by the two chambers of representatives. The king's words were — " the draught of a law regulating the practice of medicine will shortly be laid be- fore you." Without question, this is taking a right view of the national impor- tance of medical affairs. But when shall we hear any reference to such vulgar matters as physic and surgery from the lips of our sove- reign, on meeting her two houses of parliament ? When will the lords and commons of England be recommended to take the state of medical legislation in this country into their serious deliberation ? We would commend these questions, and the considerations to which they give rise, to the reflections of those in authority. In Prussia, at a time of unparalleled warlike agitation, questions of medical government are still thought worthy of even royal notice. And it is not the Prussian medical code which is affected by any of the monstrous wrongs and inconsistencies which are rife in our own professional regulations. We do not hesitate to declare that the present laws relating to medi- cine in this country are a national disgrace. England has now been blessed with thirty-five years of uninterrupted peace, yet the medical profession, essentially a profession which might be expected to flourish in such an epoch, is at the present time in a state of injudicious anar- chy. Practically speaking, all the laws relating to medicine are sus- pended. Thousands of mercenary and uneducated pretenders live SELECTIONS. 173 by preying upon the health of the community. Murder by the quack is the only kind of murder tolerated and excused by the forms and principles of our courts of law, as now reduced to practice. Great Britain in 1850, is the only civilized country under the sun in which the government at once takes a revenue from quack medicines, and permits the most ignorant knave to prostitute medicine for purposes of gain, and with murderous results, without let or hindrance, [save some of the United States — Ed.'] Such a state of things would be a dis- grace to a semi-barbarous country. The millions ruled by the knout are protected from such a state of things. The rights of life and health are the only rights not protected in this country. Let any pre- tender attempt to enter a pulpit, and he would be removed by the po- lice without much ceremony. Let any man appear in our courts of law as a solicitor or barrister without a just qualification, and he goes straight to prison as a reward for the intrusion. But any fool or vaga- bond may take the place of the regular practitioner at the bedside of the dying, and administer the most hazardous medicines in perfect ignorance, and with perfect impunity. The false maxim of our laws, as at present interpreted, is, that he is no more a criminal than a Chambers or a Brodie when death ensues. Conscience and property are abundantly protected ; life, human life, is the only thing not worth caring for, in its grosser violations, by the state ! Against cholera, which has visited us twice in this century, the whole kingdom was in agitation ; but against quackery, a greater de- stroyer, and always with us, government have palsied limbs and tongues, and the laws are really dead. Immense preparations are made, and very properly to prevent disease, but none to defend its victim from the ignorant and empiric. Sewers may not emit their odors, nor chimneys their smoke, on account of the public health, but Coffinites, Morrisonians, and all the genus of quacks, may pursue their pestilent steps unmolested and unpunished. How long are these things to continue? Surely some virtuous minister will arise, who will not think the concerns of the health of our population, and the defence of the sick, unworthy of his care. Something more than a civil reception of deputations, and smooth an- swers to addresses, are necessary before this great question can be settled. Its adjustment would make the fame of any minister, and en- title him to the gratitude of this and succeeding generations. It can- not be said that the profession of medicine is unworthy of such a boon, as the restriction of medical practice to properly qualified per- sons would prove. The calls upon us in the public service, and in the vast machinery of charitable ministration of the profession to the sick, should alone entitle us to such reform of the laws relating to medicine. More than this, the rights of the lives of the sick poor to legal defence demand it. Glad indeed shall we be if, at the next meeting of the British parliament, our sovereign should echo the words of the king of Prussia, and tell her assembled lords and com- mons, " the draught of a law regulating the practice of medicine will shortly be laid before you." — LanccL 174 SELECTIONS. Missouri State Society. A medical convention has recently been held at St. Louis, which was largely attended, and the business of which was conducted in the right spirit. It resulted in the formation of a state society, the elec- tion of officers, appointment of permanent committees on various topics. We observe that, on motion, all the members of the schools were excused from the committee on medical education. Whether this was prompted by the innate modesty of the excused, or signifi- cantly done by the excusers does not appear. We observe that by the law of Missouri, " every person or co-part- nership of persons in the state, who shall follow the practice of medi- cine for a livelihood, in whole or in part, is declared a physician." The repeal of this enactment will forthwith be sought, on the ground that " such interference of the legislature, in pronouncing upon the qualifications of physicians is uncalled for, and unjust to the medi- cal profession who are supposed to be the best judges of its own fel- lows and of their abilities." There is cause to apprehend, however, that no success will attend the effort ; for in these degenerate days, legislators are wont to go for the " largest liberty," and run into latitu- dinarianism in their horror of monopolies. Their law is no worse than ours in New York. — N. Y. Med. Gazette. A Portion of a Gall-bladder discharged externally. — Miss T , aged forty-eight, has had a very severe cough and purulent expectoration, attended with signs of a cavity in the left lung, and other symptoms of phthisis, for more than twenty years. About eight years ago she had an attack of vomiting and diarrhoea, with faintness, when a tumor was discovered on the right side of the abdomen, but apparently un- connected with the liver. As it increased in size, the tumor passed more into the centre of the abdomen, leaving a marked sulcus between it and the edge of the liver. For twelve months it had descended toward the right iliac region, where it pointed, and burst in April last, a little lower than the edge of the transversalis muscle, and midway between the spine of the ilium and the pubes. The discharge at first was very offensive, consisting of pus, followed in a few days by num- bers of hydatids, of various sizes, from that of a pea to that of a tur- key's egg, and some very minute ones, in clusters, with pedicles like a bunch of grapes, and striated externally. In about five weeks the hydatids were all expelled, and the pus became healthy and less offen- sive. The opening continued to discharge till the 11th of August, when she had another bilious attack, and the discharge ceased ; the abdomen became tense and tender over the right side ; occasional ri- gors took place ; and on the 15th the orifice re-opened, discharging pure bile. This continued to flow, to the amount of about a pint a day, till the 24th, when a slough came away, which, on examination, proved to be a portion of the gall-bladder, having small calcareous plates imbedded in it, similar to some that had passed occasionally SELECTIONS. 175 from the wound. The bile has continued to pass in greater or less quantity, almost uninterruptedly, to the present time. There is now about a drachm passed in twenty-four hours. The patient's health has varied considerably, as she is sometimes able to go about the house, and again has been reduced so low as to not be able to sit up in bed without support. — -Lancet. A Piece of Bone and Teeth, which were dissected from between two layers of Membrane forming the walls of an Ovarian Cyst, taken from a Girl after Death. — Fliza F , aged twenty-two, single, was admitted at the Stoke Newington Dispensary, under Dr. Duesbury, August 9th, 1850, with dropsical swellings, distending so uniformly the abdominal parietes, that it was difficult to diagnose whether it was ovarian dis- ease or ascites. She complained of weakness and inconvenience from the weight and size of the body. She stated that she had been ailing for three years and upwards, during which period she had suffered much from pain in the left side of the abdomen, but had not perceived her body enlarging more than two years ; that it had increased much more rapidly of late. She attended at the dispensary, and slightly improved in health under tonics and diuretics, until a fortnight previous to her death, when she was attacked with peritonitis, and died on the 7th October. Mr. Price attended her for a considerable period for what he considered to be an ovarian tumor ; and four months previous to her being admitted a patient at the dispensary, (in consequence of the lady with whom she lived as servant having suspicions of her be- ing pregnant,) he sent her to Dr. Lee, who pronounced the uterus to be unimpregnated, and confirmed the previous diagnosis as to the ex- istence of an ovarian tumor. On opening the abdomen, the left ova- rium was found to have been converted into a cyst, occupying the greater portion of that cavity, the viscera of which were pressing in every direction. A few recently deposited threads of lymph extended from its anterior surface to the peritonaeum, lining the abdominal pa- rietes; otherwise it was perfectly detached, except by its peduncle, which was not larger than the little finger, and consisted merely of the obliterated Fallopian tube, enlarged vessels and peritonaeum. The cyst, together with the uterus and appendages were removed ; and on opening the cyst, from three to four gallons of a cream-colored fluid escaped, suspended in which were numerous flakes of fatty matter; it also contained a conglomerate mass as large as the fcetal head at six months, consisting of hair, (from four to five inches long,) and this fatty substance matted together, besides many smaller pieces of the same substance. The cyst was divided by tranverse bands, and also into pouches or smaller cysts, opening into the common cavity ; ad- hering to the walls in places were considerable quantities of the fatty matter, and attached hair, similar to that in the mass ; and between two layers of the membrane, forming the walls of the cyst on the left, side, was the specimen produced. The teeth are in every respect per- fect, with their fangs inserted into the processes of the bone, resem- 176 SELECTIONS. bling the alveolar processes of the jaws. The right ovarium was rather larger than usual, congested, and contained several small cysts, the size of a pea, filled with fatty matter. The uterus presented the appearance in all respects of that of a virgin, and healthy, with the exception of slight congestion, which might be merely post-mortem. Dr. Baillie mentions similar fatty matter, hair, bone, and the rudi- ments of teeth, (but without fangs,) having been found in ovarian tu- mors, and under circumstances leaving little doubt that they had been formed independently of impregnation. One case occurred in his own practice. In another, published in the Philosophical Transactions, this change was found in the ovarium of a child, whose age did not exceed twelve or thirteen years, with the hymen perfect, the uterus not in- creased in bulk, as is usual at puberty, together with the other signs of puberty wanting. From the fact of the uterus being totally devoid of all those changes that follow impregnation, whether the foetus be developed within its cavity, or, as in extra-uterine fcetation, within the ovarian or Fallopian tube, from the respectability of the girl's parents, together with the good character she herself had borne, and her anxi- ous desire that her body should be opened, for the satisfaction of her friends, in consequence of the suspicion her appearance had excited, Mr. Denny was induced to believe that in this case there had been no impregnation. The consideration of this case suggests whether an ovum which the stimulus of the catamenial period caused to burst from the Graafian vesicles, and which was prevented from passing off with the menstrual discharge by the impermeability of the Fallopian tube, might not become adherent to the lining membrane of the ovary or Fallopian tube, and thus obtain nourishment, setting in action a power which may be inherent in it, of developing the structures of the body, but in an incoherent manner, without the power to regulate the formation, or to produce a circulating s}7stem or nervous centre, necessary to the perfect development and independent life of the foetus ; the latter power may emanate from the male, exerting an in- fluence in some way analogous to the electric influence exerted in crystallization, of attracting and arranging the particles, so as to give a definite form, and thus to characterize the individuality of a salt. — The statistical information furnished by the record of these cases, es- pecially with evidence of existing virginity, may, by affording data for physiologists, enable them at some future period to throw light upon the functions of the ovary, and upon the elements supplied to- wards the formation, and the power exercised over the development of the foetus by the sexes individually, and may also prove of practi- cal importance in removing the odium which a supposition of the ne- cessity of impregnation in such cases as the above might cast upon the fair fame of the patient. — lb. Etiology of Tuberculization. — A Mons. Wanner has written an essay attributing the production of tubercle to the presence of lime in the soil of the district in which the patients reside. He brings some curi- ous facts to bear in favor of his theory. SELECTIONS. 177 ITEMS. The distinguished professor of obstetrics in the University of Edin- burg, Dr. John Y. Simpson, has been lately elected president of the Royal College of Physicians. — The St. Louis " Probe" has died of angemia. — Dr. James M. Austin, late of Virginia, has been appointed professor of materia medica and therapeutics in the medical depart- ment of Georgetown College. — Queen Victoria is a fellow of several of the British learned societies ! — The American Dental society have repealed their law prohibiting its members from using any other foil than pure gold for plugging teeth. — Royer Collard, prof, of hygiene, &c, lately died in Paris, age 47. — The British government is about to erect a bronze statue on a monument to Jenner. — Suits against doctors and apothecaries for mal-practice are reported in almost every newspaper. — The number of matriculates at the University of Virgi- nia for the present session is 381, of which 271 are from Virginia. The class of medicine numbers 93, that of physiology and surgery 96, anatomy 97, and chemistry 180. — Dr. Rush was, perhaps, one of the most untiring students that ever lived. Two young physicians were conversing in his presence once, and one of them said — " When I fi- nished my studies" " When you finished your studies !" said the doctor abruptly ; " why you must be a happy man to have finished so young. I do not expect to finish mine while I live." t3^° At the request of many subscribers in the country, we publish below the Fee-bill of the Richmond profession. Like all other things, every item of it cannot meet with unanimous approval, but, as a whole, it has as few defects probably as any other which we have examined. He who cannot be regulated by this one, will not be bound by any instrument of the kind. TARIFF OF FEES Adopted by the Medical Profession for Richmond City. Medical. 1. For each visit in the city during the day, $ 1 2. Do. do. when detained, for each hour after the first, - - - - 3 3. For single visits and advice in a case in which no further visits are required, - - 2 to 10 $3T This is not intended to apply to those cases in which the physician is considered the regu- lar medical attendant. 178 TARIFF OF FEES. 4. Each clay visit at an hour appointed by patient or his friends, - 5. Prescription or advice anywhere, 6. Visit in the city between 10 o'clock P. M. and sunrise, - 7. Visit without the corporation, but not more than half a mile, - S. Visit beyond that distance $2; for every mile thereafter to ten miles, - 9. Visit to the country after 10 o'clock P. M., with above mentioned mileage, 10. Ordinary consultations, - 11. Consultations during prescribed hours of night, visits included, - 12. Detention with patients all night, 13. Do. at patient's house lor days, per diem, - 14. In cases of several patients at same house, charge visit to one, and prescription or advice to each other, at - 15. For written advice or opinion, 16. For oral opinion of health or disease, 17. For stethoscopic examination, 18. Opinion involving a question of law, 19. Post mortem examination in cases of legal investi- gation, - 20. Post mortem made at request of family or friends, 2 to 5 1 5 1 1 5 5 10 10 to 20 20 to 100 1 5 to 20 2 to 10 5 to 20 10 to 50 25 to 50 5 to 15 Obstetrical. 21. Attendance on simple natural cases of labor, and attention for eight days after delivery, provided no serious ailment occurs to mother or infant, (in which case visits are to be charged,) 22. Attendance on complicated, protracted or instru- mental labors, including visits for eight days, 23. Attendance on cases of abortion, exclusive of visits and other services, 24. Delivery of placenta, - 20 30 to 100 10 10 to 20 Surgical. 25. For bleeding, exclusive of visit or advice, 26. For bleeding in jugular vein or arteriotomy, 27. Cupping, - - - 28. Introduction of seton or forming issue, 29. For pumping stomach, 30. Dressing recent wounds, 31. Each subsequent dressing, 32. Opening abscess or exploring tumor, 1 2 to 5 2 to 5 5 5 to 20 5 1 1 to 5 TARIFF OF FEES. 179 33. Vaccination of one white person $ 3; of two at same time $ 5; for each one thereafter in same family at same time, -._■•- 34. Vaccination of single slave $2; each one there- after, &c. as above, 35. Re-vaccination, white or black, 36. Extracting teeth, each, - 37. Lancing gums, - 38. Plugging posterior nares, - 39. Application of truss, - 40. Reduction of prolapsus ani, 41. Examination per vaginam or per anum, 42. Introduction of pessary, - 43. Introduction of speculum vaginae, first time $5, each subsequent time, - 44. Introduction of bougie to explore urethra, 45. Cauterization of urethra, - 46. Operation of sounding the bladder, 47. Introduction of catheter into bladder first time, 48. " " each subsequent time, 49. Treating stricture of urethra, 50. Treating syphilis, - 51. Treating gonorrhoea, - 52. Operation for phymosis or paraphymosis, 53. Palliative operation for hydrocele, 54. Radical cure of " - - 55. Operation for hypospadias or irregular opening of the urethra, - 56. Operation for fistula in ano, or in perineo, 57. " for haemorrhoids, 58. " for imperforate anus or vagina, 59. Reduction of hernia by taxis, 60. Operation for strangulated hernia, 61. " for recto-vaginal, or vesico-vaginal fistula, 62. Stone in the bladder, - 63. Extraction of calculus from urethra, 64. Puncture of bladder, - 65. Paracentesis abdominis $10, each subsequent time, - 66. Paracentesis thoracis, - 67. Caesarian section, - 68. Extirpation of uvula, - 69. " of tonsils, 70. " of mamma, - 71. " of diseased ovary, 72. " of testicle, 73. " of tumors, - 74. " of polypus uteri, 75. " of " nasi, 76. " of eye, 1 1 1 1 to 5 5 5 to 15 5 to 40 5 to 15 5 to 10 2 to 5 5 to 50 10 to 50 5 to 50 5 1 20 to 150 20 to 200 15 to 50 5 to 20 5 to 10 20 to 50 15 to 50 20 to 150 20 to 100 10 to 100 5 to 50 50 to 200 50 to 200 50 to 500 10 to 20 20 to 50 5 20 to 50 100 to 500 5 to 15 10 to 50 20 to 100 50 to 250 50 to 100 10 to 200 20 to 100 10 to 50 100 180 TARIFF OF FEES. 77. Operation for cataract, - - - 50 to 200 78. " for artificial pupil, - - 50 to 200 79. Other operations on the eye and its appendages, 5 to 50 80. Amputation of superior or inferior extremities, in- cluding dressing and attendance, - 40 to ]00 81. Amputation of the finger, thumb or toe, &c, - 10 to 30 82. " of penis, - - 20 to 50 83. Evulsion of nail on finger or toe, - - 5 to 30 84. Application of trephine, - - 50 to 100 85. Exsection of diseased bone, - 20 to 100 86. Removal of upper or lower jaw or portions, - 15 to 200 87. Exsection of diseased joints, - - 10 to 100 88. Operation for artificial joints, - 20 to 100 89. Reduction of luxations of greater joints, - 20 to 100 90. " of " of lesser joints, - 10 to 20 91. " fracture and first dressing, - 5 to 30 92. Treating fractures, including dressing and attend- ance, - - - - 20 to 100 93. Treating fractures of cranium, with or without tre- panning, - - - 10 to 150 94. Operation for aneurism, - - 20 to 180 95. " for harelip, - - - 20 to 50 96. " for ranula, - - 5 97. Division of fraenum of tongue or penis, - 2 to 5 98. Operation for club foot, - - - 20 to 100 99. Operation of myotomy or tenotomy, - - 10 to 100 100. Plastic operations, - - - 10 to 100 101. Extracting foreign bodies from pharynx or oeso- phagus, - - - 5 to 50 102. Laryngotomy or trachecotomy, - - 20 to 50 The above fee bill, founded on a just consideration of the important services which physicians are called upon to perform, is intended to enable the practitioners of Richmond to exhibit uniformity in their rates of charging, and it is expected that every member of the profes- sion will, in good faith, conform to it in his charges, whenever the pe- cuniary circumstances of the patient are not such as clearly to forbid it. It is considered obligatory upon physicians to collect their bills at least once a year, whenever this can be done without serious incon- venience to the patient. We will not attend either individuals or a collection of persons by the year, at any stipulated price or under any circumstances. In case any one should transgress these rules, he shall be considered beyond the pale of the profession, and all consultations withheld. We will refuse to hold medical communion with those who may them- selves consult with such persons knowingly. Richmond, May 1850. THE AND No. 4.] RICHMOND, APRIL 1851. [Vol. L Report of the Committee of the Medical Society of Virginia, On the Utility and Safety of Anesthetic Agents. [ Read at the March Meeting. ] The committee, appointed by the Medical Society of Virginia to enquire into the experience of the medical profession of the city of Richmond, in regard to the utility and safety of anaesthetic agents, respectfully report : That we have entered upon our duties deeply sensible of the re- sponsibility which devolves upon us. We have undertaken to collect the facts fully, to analyze them carefully, to classify them correctly, and to interpret their meaning faithfully, uninfluenced by a prejudiced hostility to, or an enthusiastic admiration of, the agents in question. We believe that we have performed these duties honestly, and we present herewith the data on which this report is based, viz : the se- parate reports of the physicians of this city who have used anaesthetic agents in their own practice, and who have witnessed their use abroad. In addition to this source of information, we have, in accordance with the spirit of the resolution under which we were appointed, collected materials from those gentlemen who confine their practice to a branch of minor surgery, viz : the dentists of our city. They have politely and promptly responded to our application. We believe that this report, if adopted by the society, will have considerable influence upon the mind of the medical profession of the state and of the community at large. All are interested in its accu- racy ; for there is no one who may not at some time have occasion to decide upon the propriety of inducing anaesthesia in his own person. It is not surprising that one who witnesses the anaesthetic state for the first time should feel considerable apprehension about the ultimate result. To see a strong man reduced in a few minutes to a state of utter helplessness, the most powerful intellect annihilated, the acutest senses abolished, and every evidence of life become extinct, except the breathing and the pulse, and even these rendered slower and weaker, is well calculated to alarm the inexperienced. It resembles 182 TRANSACTIONS OF THE MEDICAL SOCIETY OF VIRGINIA. too nearly the condition of one suffering under fatal disease or injury of the brain, to be viewed for the first time with indifference. He may well ask, is it not rash presumption to lead a human being so close to the portals of death ? What, if we should loose the bond of life, and we should witness those dark portals inclosing him in their awful embrace forever ! But we would reply to such an one — Have you never tapped one of the heart's tubes, and drained the vital current until even a more alarming condition was produced ? Have you never seen from this cause the countenance blanched, and the eye become vacant, and the limbs tremble, and the stoutest man reel and fall senseless as a corpse, the heart become still, and the chest cease to heave, and not a breath or motion occur to give evidence that life is not extinct? Alarming as is the appearance of syncope produced by blood-letting, we do not hesitate to induce this state, not only in the treatment of those dis- eases whose fatal course requires them to be promptly and boldly ar- rested, but even when a dislocated limb is to be replaced, or an in- flamed eye is to be relieved. This latter condition has ceased to alarm us, because we have become familiar with it. The former is one with which a large number of the medical profession have had no experi- ence whatever, and still more regard with a feeling of undefined dread. Every contribution to the fund of knowledge on this subject is therefore a valuable acquisition to the science of medicine, and pro- motes its noble practical design of alleviating human suffering. We have been furnished with the results of observations on thirteen hundred and eighty -four cases of anassthesia, occurring in the practice of physicians and dentists in our city. Nearly all the parties concerned being residents, we have the best opportunity of judging of the accu- racy of these reports. The following table exhibits the principal facts which could be readily arranged in a tabular form, and the remainder will be stated in a more full and detailed manner : Agents Used. IB o.S Physicians' Reports. Chloroform, Ether, Ether and chlo- roform, Dentists' Reports. Chloroform, Ether, Total, gtt5-|iv "ss. — ?i gtt. 10— ?iss. ?ss.-?iv 291 1 99 I loj 215 149 400 428 556 984 400 1384 674 889 674 823 15 months to 80 years. 4 to 50 years, Less than 1 minute to an hour. 10 seconds to 1 hour. 1 minute to seve- • ral hours. 30 sec. to J hour. REPORT ON ETHER AND CHLOROFORM. 183 Besides these cases, we have been informed of several others which have not been reported. The following observations require to be presented in a more de- tailed manner. Time required to induce ancesthesia. — Variations were produced by several causes, viz : Age, sex, idiosyncrasy, and design with which the agent was administered. Age. — Children were much more susceptible than adults. For ex- ample, a child four years old was brought into a profound state of anaesthesia in less than one minute, while the average time required to induce a similar condition in adults was about eight minutes. Old and infirm persons yielded more readily than the middle-aged and the robust. Sex. — As a general rule, females were more susceptible than males : the difference, however, was not very striking. Physical condition. — Intemperate persons offered the greatest re- sistance. A case of this kind is reported to have required an hour to produce anaesthesia. In one instance, it was administered to a patient habituated to the use of opium, for the purpose of relieving severe attacks of neuralgia. In this case, inhalation was continued an hour before complete anaesthesia was produced ; but it should be borne in mind that the patient was then suffering from a severe attack of the disease. Design of administration. — When this was simply the extraction of a tooth, a sufficient state of insensibility was generally produced in from 2 to 5 minutes ; when a more profound state was required, the time averaged about 8 minutes, and it was not unfrequently extended to 15 or 20 minutes. Mode of administration. — If a large quantity were poured upon a handkerchief or other inhaler, and applied close to the face, the effect was more sudden. Duration of ancesthesia. — This has varied, from causes similar to those which affected the readiness with which patients were brought under the influence of the agent, and the period during which this in- fluence was maintained. If the inhalation were continued a short time, and consequently a small amount of the agent used, the effects were evanescent. If it were prolonged, with the use of a larger amount, they were more persistent. If the design was the extraction of a tooth, for instance, the patient frequently recovered so rapidly as scarcely to afford time for -the operation to be completed, and the shock of the operation appeared to assist in thoroughly arousing the patient. Frequently, a prolonged state of anaesthesia was desired for cases of midwifery or surgical operations. In these cases, it was usually ne- cessary to repeat the inhalation several times, whenever the patient appeared to be returning to a state of consciousness. In this mode anaesthesia was maintained several times for more than an hour, and in one instance between two and three hours. Young children, who yielded in half a minute or a minute, continued in a state of anaesthesia about five minutes. 184 TRANSACTIONS OF THE MEDICAL SOCIETY OF VIRGINIA. Adults, who required about 10 or 15 minutes, were thoroughly roused in from 10 to 20 minutes. To these definite causes, we may add some obscure idiosyncrasy, by which the time was greatly shortened or prolonged. This, however, forms no greater objection to their use, than to that of other active re- medies, whose effects we are obliged continually to watch cautiously on this account. In a few cases, the effort to produce anaesthesia was so tedious, that it was abandoned as impracticable. This occurred more frequently in the use of ether than in that of chloroform. When the latter agent failed, it was usually in cases of intemperate persons, or else the ope- rator had not sufficient confidence to proceed with boldness. Proba- bly to the latter cause all, or nearly all, cases of failure are to be attributed. Quantity administered. — This also was varied by causes similar to those already named, and the agent employed. About 30 drops of chloroform were administered in about a minute, and one drachm in about 5 minutes. This would make an average of about one drop to two seconds, counting 120 drops to the drachm. Of course, the mode of inhalation and the temperature would greatly affect this estimate. If it were simply necessary to induce anaesthesia, the average quantity was about a drachm. In several instances, as much as one ounce was administered. In others, one ounce and a half. One case occurred in the practice of one of our most accurate physicians, in which from 3£ to 4 ounces were required to produce anaesthesia. Ether. — A much larger quantity of this agent than of chloroform was required. The average quantity was from Iss. to Ij. As large a quantity as 5iv. was administered, and in one instance three gills were used in three days. Effects during administration. — At the commencement, there was usually considerable increase of the force and frequency of the pulse. Often the respiration was impeded, and the patient had to be urged to make full inspirations. Sometimes there was coughing and a sense of suffocation, especially if the administration were carried on too ra- pidly, or there were an insufficient supply of air. In about a minute, the patient complained of noises in the head, as of a multitude of wheels or hammers in motion. In two or three minutes, the face be- came slightly flushed, and the veins of the temple became turgid. Occasionally, at this period, the patient was very talkative, or burst into immoderate fits of laughter or crying. He usually answered when spoken to, and obeyed directions. Occasionally, spasm of the limbs occurred, which soon passed off as the anaesthesia became more profound. Sometimes there was considerable resistance, the patient struggling violently to make his escape, and refusing to take any more inhalations ; but he was usually soon subdued by the persevering ap- plications of the anaesthetic vapor. The pulse fell considerably ; the respiration became slower ; the muscles were perfectly relaxed, and all the functions, save those of mere organic life, were suspended. The subject was in a state of mere vegetable existence. The senses no longer gave intimation to the spiritual being within, of what was REPORT ON ETHER AND CHLOROFORM. 1S5 occurring to its material tenement or around it. Its nervous tentacula, so exquisitely sensitive to impressions from the external world, were utterly paralyzed. It was as if dead, and its own body was the sar- cophagus which encased it. A few instances occurred, however, in which prolonged administra- tion failed to deprive the nerves of all irritability. Although there was a state of perfect composure, and a very depressed state of the pulse — so much so that it was deemed imprudent to push the impres- sion further — yet, whenever any attempt was made to operate, the pa- tient became restless, and sometimes complained of pain. But even in these cases, when the patient was fully roused, he had either no re- collection, or a very faint one, of anything which transpired during this imperfect state of anaesthesia. If we take a physiological view of these various grades of insensi- bility, we may arrange them under the following heads : 1st. Incomplete anaesthesia, in which the nerves of ordinary sensa- tion and motion are obtunded, while those of reflex action and the sympathetic retain their functions. The other senses are preserved : the mental powers are confused. 2d. Complete anaesthesia, in which the cerebo-spinal system, ex- cept the medulla oblongata, is paralyzed. The sympathetic continues to retain its functions. We now proceed to consider these effects more in detail. The pulse is usually much excited at first, running in one instance, in which it was carefully noted, from ninety up to one hundred and fifty in the space of two or three minutes, and after the same interval sink- ing to ninety again. One of the most reliable signs of complete anaes- thesia was, sinking of the pulse in regard to force and frequency. Sometimes it was very small and weak. The eye was soon closed, and on raising the lid before the anaesthe- sia was complete, the pupil was observed to be enlarged. This was owing to its being protected from light by the lids ; for when the light was admitted the pupil immediately contracted. In this state, the pu- pil was rolled up under the upper lid ; but when the second state was induced, the eye was fixed with its axis directed forward. The pu- pils were contracted, and perfectly insensible. The lids no longer closed spasmodically when opened. There was usually some conges- tion of the conjunctiva. The hearing was remarkably retained in the first state, the patient often answering questions and obeying requests, of which he had no recollection afterwards. Stomach and bowels. — Nausea and vomiting usually occurred if the stomach were full, but as soon as it was emptied anaesthesia was readily induced. In one instance, inhalation was frequently repeated during two or three hours, and it always produced distressing nausea and vomiting, just as anaesthesia was about to become complete. The best remedy was crushed ice taken into the stomach. The sphincters of the bowels have been observed, though rarely, to become relaxed. In one case, that of a boy, the bowels were evacu- ated involuntarily. In the case of an old man of 80, there was an es- 186 TRANSACTIONS OF THE MEDICAL SOCIETY OF VIRGINIA. cape of flatus. It was not unusual to hear the rumbling of flatus without its escaping. Bladder. — In two instances it discharged its contents involuntarily. The first case was that of a child incompletely anaesthetized by ether. The second was that of an old drunkard, who required an hour's in- halation to produce complete anaesthesia. Respiratory organs. — If the vapor were suddenly applied close to the mouth and nose, it was apt to produce coughing and a sense of suffocation, which were immediately relieved by removing the source of irritation, and gradually approximating it again. The patient was apt to restrain the action of the respiratory muscles, and required to be urged to take full inspirations. When complete anaesthesia com- menced, the respiration frequently became quite full and strong ; after- wards it was chiefly abdominal. Stertorous respiration was occasionally observed when anaesthesia became profound. This was alarming to the inexperienced, but was never followed by injurious consequences. It was one of the most certain signs of complete anaesthesia. Blowing respiration was once observed in the case of a feeble old man, anaesthetized by ether. Muscular system. — In the first state there were, not infrequently, ir- regular spasmodic contractions ; sometimes strong convulsions : as the second stage ensued, these ceased, and the muscles became per- fectly relaxed. Uterus. — When anaesthesia was profound, the contractions of the uterus were impeded during delivery at the full term. In case of abortion, they were entirely suspended. When anaesthesia was mode- rate, they were as vigorous as usual. The salivary glands and mucous lining of the mouth and fauces were occasionally considerably excited, causing the patient to spit fre- quently. Skin. — When inhalation was prolonged, the cutaneous surface was not infrequently bathed in a copious perspiration. If the wetted sponge or handkerchief were allowed to touch the face, it produced a burning sensation and an erythematous blush. This effect was quite painful, if it came in contact with the vermillion border of the lips. Comparative effects on children and adults. — Children were much more rapidly anaesthetized, and by a much smaller quantity than adults were. In other respects the effects were similar. Except in one in- stance, where an over dose of chloroform was accidentally adminis- tered, and another in which involuntary discharge of urine occurred during a partial administration of ether, the unpleasant effects ob- served in adults were not observed in children. Comparative effects on males and females. — The latter were gene- rally more susceptible than the former. To this rule there was one exception, in the case of a negro woman, who, on two different occa- sions, required from 3£ ounces to 4 ounces of chloroform. Hysteric convulsions were peculiar to females. Subsequent effects and their treatment. — A condition similar to the REPORT ON ETHER AND CHLOROFORM. 187 first state of angesthesia succeeded to the second or profound condi- tion, the functions being gradually restored. In other words, the effects passed off in the inverted order of their occurrence. In very- many cases, the patient awaked as from a pleasant dream, delighted with the agreeable sensations he had experienced. Nervous system. — Drowsiness was the most common consequence, especially when the inhalation had been prolonged. The best prac- tice was to allow the patient to yield to this feeling and sleep off the effects. If it were desirable to dispel it, this was best effected by dashing cold water in the face, a draught of cool air, and moving about. It was remarkable, that sensibility to pain was not recovered immediately with consciousness. In one instance, the patient con- versed about the operation which had just been completed, occasion- ally looking at the part, during the space of ten minutes before he be- gan to complain of pain. This accords with our remarks on the order of the subsidence of the effects. Hysteric convulsions occasionally occurred in young females. Some- times there was high nervous excitement, with excessive talkativeness, lasting from an hour or two to twenty-four or thirfcy-rsix hours. Quiet- ness, sponging the face with cold water, and ice to the head were suf- ficient treatment. Sleep was produced, from which the patient awaked quite calm. Headach was sometimes complained of for a short time : in a few instances, it lasted for a day or two. Chilliness and coldness of the extremities. This was a rare conse- quence, and was relieved by warm, stimulating drinks and warmth to the surface. Eye. — Blindness was complained of in the case of a female for more than an hour, while the hearing was as acute as ususal. This was speedily relieved by a warm, stimulating drink. The conjunctiva occasionally remained in a congested condition for an hour or longer. Muscular system. — General debility and an unsteady gait in walk- ing, as of one under the effects of intoxication, often occurred, lasting from a few minutes to half an hour or longer, usually dependent upon the length of time that inhalation was continued. Digestive organs. — Nausea and vomiting having commenced during inhalation, sometimes continued afterwards ; and were relieved by swallowing crushed ice, or by an external sinapism. In the case of a child, copious evacuation of the bowels occurred in twenty minutes after recovery. In compiling this report on the effects of anassthetic agents, we have felt greatly the want of accurate and minute records of cases. About twenty have been furnished, of which the observations were carefully made and noted immediately in a case-book kept for the purpose. One of these, we deem sufficiently interesting to be reported in full, as the operator and subject were both physicians experienced in the use of anaesthetic agents. Dr. P., about 25 years age — in good health, of rather spare form, excitable and cheerful — desired me to administer chloroform and ex- 188 TRANSACTIONS OF THE MEDICAL SOCIETY OF VIRGINIA. tract two teeth, in order that he might have personal experience in re- gard to a new agent, which he occasionally administered to others. I determined to avoid profound anaesthesia. Quantity used. — Chloroform 3jj. on the sponge and oiled silk inhaler. Effects. — Incomplete anaesthesia in five minutes, marked by occa- sional laughter and incoherent expressions. Entire insensibility to pain in ten minutes. The muscles of the lower jaw were completely re- laxed. One tooth was then extracted without resistance, although he appeared somewhat conscious of the operation. Decided signs of re- turning consciousness occurring, I remarked, " I had better give you some more to extract the other tooth." To which he replied, " Go on without it ; I don't think you will hurt me." He opened his mouth at my request, and I immediately extracted the other tooth, when he com- plained of slight pain. In ten minutes he recovered ; stated he was insensible, or nearly so, to the pain, and exclaimed several times, " What a wonderful discovery ! " " Is it not a glorious discovery? " During the whole period he answered questions, though rather in- coherently. The following is a description of his sensations, written by himself: Wishing to have two large molar teeth extracted, and also desirous of relieving myself, to some extent, from responsibility in administer- ing it to others, Dr. B. was kind enough to put me under the influ- ence of this wonderful agent. The following are my recollections of its effects upon myself. While inhaling the chloroform, I endeavored to resign myself fully to its influence, determining at the same time calmly to observe its sensible effects. The first impression was that of most decided exhilaration. I found myself laughing, at what, I knew not; then commenced the buzzing or ringing in the ears, follow- ing which was an illusion of countless stars, with a diameter of about half an inch, and of bright colors, (blue and red, I think,) each revolv- ing on its own axis with great velocity. Up to this time I could hear any question asked me, but was rather indifferent to other sounds about the room. My mind seemed engaged with the bright illusions above mentioned, and now and then occupied in a sort of abstract contemplation, hard to describe. From this state, (how long it con- tinued I cannot say, but it seemed only a short time,) I found that I began to revolve slowly myself, (not on my own axis, however,) and in a few moments joined in the common whirl. It seemed to me that I was on the end of some great lever, which revolved with inconceiv- able velocity — not producing any fear, however, but seemingly a sen- sible giddiness. From this condition I lapsed, in a few moments I suppose, into complete insensibilit}r. The feeling was very similar to that I have felt while fainting. It was at this time, I presume, that the first tooth was extracted. In a few minutes, I became somewhat conscious, and recollect Dr. B.'s putting his hand into my mouth, at the same time remarking he would give me a "little more." I think I told him to pull out the other without giving me more — that I would not feel it. He complied with my request, and I distinctly recollect his putting the forceps upon the tooth, and was conscious of some pain, but knew scarcely from whence it proceeded. I seemed to make some resistance. REPORT ON ETHER AND CHLOROFORM. 189 For about a half hour after recovery, had some pain in the frontal region, and noticed slight congestion of the conjunctiva. The most remarkable effect of this agent upon myself, was the current it seemed to give to my thoughts for about two weeks afterwards. In this I am not mistaken. I frequently found myself making exclamation, spon- taneously it seemed, such as I discovered myself using when recover- ing from the effects of the chloroform. I was not aware of any unpleasant consequence from the use of this agent — no depression of body or mind. The next case is one of such extraordinary character, that we would not feel justified in reporting it, if we had not satisfied ourselves of the accuracy of the facts. They were reported by a son of the indi- vidual, and were confirmed by the statements of several respectable apothecaries, together with the personal observations of two members of the committee. J., about sixty years of age, blacksmith, of fine athletic form, had enjoyed such uninterrupted good health, that he had not been known to lose a day's work during twenty years. It was his habit to work every day, Sundays included, until a late hour of the night. Every Saturday night he stopped work earlier than usual, and indulged himself in a frolic. About three years since, his mind became sud- denly disordered while he was at work in his shop. He was totally incapable of applying himself to his usual employment, and imagined that he had been poisoned. He returned home and went to bed, from which he has never risen since, except for a short period. While under medical treatment for this hypochondriacal condition, it was suggested to him to use ether, which had then been just intro- duced, for the purpose of producing anaesthesia. A few trials were not satisfactory to him, and when chloroform was introduced, he soon substituted it for ether. Since then, he has continued to use it to an enormous extent. He has often inhaled a pint in twenty-four hours. On one occasion, his son left in his room a pound, which he had just purchased. On returning home six hours after, he found the bottle empty. On enquiry, his father assured him that he had inhaled the whole of it, and entreated him for more. Fearing that it would prove fatal, he refused to procure a further supply, until after an in- terval of about twelve hours, when his father's entreaties became so importunate that he yielded, and during the remaining six hours, the old man inhaled ten ounces more, amounting in all to 26 oz. in 24 hours. Probably, however, much of this wasted. One apothecary of the highest character testifies, that he has sup- plied him with more than two hundred pounds, and that he has not sold him any for a considerable time. His son declares, that his fa- ther's use of chloroform has consumed the greater part of the earn- ings of himself and brother, in one of the largest and most profitable shops in the city. He supposes they have expended at least twenty- five hundred dollars in this way during the last three years. Lately, they have succeeded in reducing the amount used, to four ounces in three days. 22 190 TRANSACTIONS OF THE MEDICAL SOCIETY OF VIRGINIA. It is remarkable, that during the period that he has been using chlo- roform, he has entirely abandoned the use of ardent spirits. About the middle of last February, two members of the committee visited the patient, in company with his son. He was found occupy- ing an attic room, lying upon a pallet on the floor, in compliance with his own wishes. His appearance was that of a hearty, fleshy man, of about sixty years of age. His pulse, respiration, in fact all his functions, we ascertained were perfectly healthy. His appetite and digestion were remarkably good. During this inordinate use of chlo- roform, he has fattened probably thirty pounds, his weight being now about one hundred and eighty pounds. He has never been unpleasantly affected in any way, either during anaethesia or afterwards, except once, when, having become insensi- ble, his head fell upon the inhaler. Then, a more profound state than usual, marked by stertorous respiration, was produced, but it wTas of short duration. We remained in the room about half an hour, conversing with him most of the time, and were several times interrupted by his urgent entreaties for more chloroform, although he had just emerged from the anaesthetic state. His remarks were chiefly on the subject of his hav- ing been poisoned, which is evidently his principal illusion. He ima- gines himself unable to walk, and refuses even to be dressed. At length his desires were indulged ; and an ounce vial, half full of chloroform, was brought to him. He eagerly grasped it ; and having drawn the bed-clothes over his face, sufficiently to cover his mouth and nose, he placed the vial to his lips, and took strong, deep inhala- tions for ten or fifteen minutes. A slight quivering passed over his frame, he rolled upon one side, and lay in a state of profound sleep. We then left him to his strange infatuation. This case proves conclusively, that the intemperate use of chloroform is attended with far less danger than is the same use of alcohol or opium. It is a remarkable fact, that in this case it has not been ne- cessary to increase the dose, which would have been required, had any known stimulant or narcotic been used, instead of chloroform. Three cases have been reported, in which fatal or permanently inju- rious consequences have been suspected; but in all of these, there were other palpable causes quite sufficient of themselves to have produced the results. That the anaesthetic agent used, even co-operated with these causes, has not been satisfactorily shewn ; and without this evi- dence we cannot admit a conclusion opposed by all the other evidence which we possess.* We now proceed to state the various occasions on which anaesthesia was used with advantage. Had our queries been more definite on this head, we might have been furnished with more interesting matter than we are now enabled to report. Surgical operations. — The cry of distress is always attractive, even among brutes, which rush instinctively to the scene of suffering, re- * The details of these cases were reported in full to the society, so far as the facts could be obtained. Two of them we do not feel at liberty to publish. The other was simply a case of fatal result, after a prolonged capital operation. REPORT ON ETHER AND CHLOROFORM. 191 gardless of danger. Among human beings, the desire of alleviating pain is one of the strongest natural impulses. Especially are our feelings enlisted, when we ourselves occasion that pain, though for some beneficial end. A timid, inexperienced surgeon, of sensitive feelings, is liable from this cause to lose his presence of mind in the midst of an operation, and thus risk the life of the patient. In such a case we can hardly over-estimate the value of an agent, by which we can reduce the human frame, for any desirable period, to a state of mere vegetable existence. Often, the patient, terrified by the thought of enduring the physical suffering of a surgical operation, has dangerously procrastinated, or even sacrificed life itself. How wonderful the relief to his agitated feelings, instead of being directed to string up his nerves to their highest pitch of endurance, to be requested simply to compose himself to sleep, with the assurance that he shall awake, to be informed of the completion of the long-dreaded application of the knife. In one instance of extreme debility, from diffuse inflammation of the cellular, tissue of the arm affecting the elbow joint, it was deemed im- portant to amputate. It was feared the patient could not withstand the shock of the operation, and yet it was believed she would sink from the exhausting effects of the disease. Chloroform was adminis- tered, the amputation was performed, and the patient recovered. Statistical tables of capital operations have shewn a fearful amount of mortality. In many of these instances the catastrophe has been attributed, no doubt properly, to that state of innervation, called the shock to the system. Anaesthesia has almost annihilated this source of danger. While the reports of this city are not sufficiently definite on this point to enable us to state actual results, we would refer the society to tables published by Professor Simpson, which prove an ex- traordinary diminution of mortality, after capital operations, in the principal hospitals of Great Britain and Europe, since the introduction of anaesthetic agents. Eye. — It has been objected, that in anaesthesia the ball is rolled up, and is in an unfavorable position for most operations on this organ. This is fully contradicted by observations in this city : several opera- tions in ophthalmic surgery having been performed upon anaesthetic patients, and in every instance the axis of the eye was observed to be directed forward. For the extraction of foreign bodies embedded in the cornea, as pieces of steel occurring among stone-masons, the po- sition of the eye and its quietude, are the most favorable that can be desired. In extraction of the lens for the cure of cataract, the only inconve- nience which occurs, is, that the ball is not sufficiently steadied by its muscles, and requires counter-support against the thrust of the knife. Occasionally, in surgical operations, anaesthesia was not sufficiently profound, nor well sustained, and then, considerable embarrassment was experienced, in consequence of the restlessness of the patient. Fractures. — For the purpose of setting a fracture, when much pain was experienced, and there was much resistance from muscular con- traction, anaesthesia enabled the surgeon to effect his object with great facility. 192 TRANSACTIONS OF THE MEDICAL SOCIETY OF VIRGINIA. Dislocations. — We possess no means by which the muscular relaxa- tion necessary for reduction can be effected with so little loss of vital force, as by anaesthesia. Blood-letting and the other usual means are followed by much more prolonged debility ; nor can we possibly in- duce so perfect a state of relaxation in any other way ; for, however great the debility of the patient may be, if he be conscious of pain, he will make some involuntary resistance, and often this is very consider- able. In anaesthesia, the muscles continued perfectly relaxed during the efforts of reduction ; and the dislocated limb was replaced with more facility than it could have been upon a lifeless body. Tetanus. — We have tried, in vain, the most powerful agents of the materia medica, to subdue the frightful parox}Tsms of convulsion, which constitute the most obvious feature of this dreadful disease. Anaesthesia abolishes all this agony. One who witnesses such a scene of intense suffering, and hears the entreaties of the patient for this means of relief, and then observes the perfect composure which follows its use, is prepared to render an acknowledgment of devout gratitude to the Giver of so great a blessing. The reports we have received do not furnish any instance, in which this formidable disease has been cured by anaesthetic agents. So far, they have produced a temporary alleviation of suffering, and have aided the use of other means. In one case in which traumatic tetanus was feared, the alarm- ing symptoms were subdued by ether as often as they appeared du- ring three days, when they finally subsided. Stricture of the urethra., with retention of urine. — One instance of this kind is reported, in which the attempt to pass the catheter produced intense pain, with a discharge of blood. Free bleeding and the warm hip bath were resorted to in vain. Anaesthesia was then induced, with the effect of giving prompt and entire relief, without the use of the catheter. Obstruction of the oesophagus in its lower part. Anaesthesia was used successfully for the purpose of passing the probang into the sto- mach. Mania d potu. — In this disease, in which a nicely-adjusted combi- nation of stimulants and sedative narcotics has proved most effica- cious, anaesthesia succeeded in giving relief, when the usual means had failed. In the cases reported, there was " flushing of the face and spasm of the extensor muscles of the whole body ; the breathing was hurried, and occasionally entirely suspended. This state lasted only a few seconds, and was relieved by throwing cold water upon the face. The patients then fell into a sleep, which lasted from ten to thirty minutes, and awoke quite refreshed." . Epilepsy. — Anaesthesia has greatly mitigated the violence and short- ened the duration of the attacks of this formidable disease. Hysteria. — In violent paroxysms of this disease, accompanied by delirium, convulsions, screams and violent resistance of control, with a full pulse, the patient was composed by a cautious administration of chloroform. While she was in this condition, free venesection was practised, followed by a large dose of morphine, and cold applica- tion to the head. The paroxysms soon began to recur, and they were REPORT ON ETHER AND CHLOROFORM. 193 again promptly subdued by chloroform. The inhalation was repeated at intervals, so as to keep up a state of anaesthesia, until narcotism commenced, when its use was dispensed with. In one of these cases, two pounds of blood were taken during anaesthesia. It should be particularly observed, that the act of deglutition was performed during anaesthesia. Convulsions from other causes have been relieved by a mode of practice similar to that last mentioned. Cramps of Asiatic cholera. — This dreadful symptom of a most ma- lignant disease has been entirely relieved by anaesthesia. In two cases, the one complicated with r^sterical symptoms, and the other in a state of collapse, chloroform was used as occasion required, with the happiest effects, and. both patients recovered. In the last case, the system, nearly exhausted by the principal symptom of the dis- ease, seemed in danger of complete exhaustion of the vital powers by the fatigue and pain of the violent muscular contractions. Tranquil sleep was produced by chloroform, and an opportunity given to the system to recruit its worn-out energies. Neuralgia. — Severe attacks of this disease have been entirely re- lieved by chloroform ; no case of permanent cure has been reported. Burns. — Anaesthesia relieved a patient from the intolerable suffering produced by this injury, and enabled the surgeon to apply suitable dressings with facility. Asthma. — No agent of the materia medica gave such prompt relief in this distressing affection as chloroform. It was premised by venesec- tion when this was indicated. In one case, continued gentle inhala- tion gave entire relief, without the use of any other means. It was used several times, with the happiest effect, in the case of a feeble person of seventy years old. Abortion. — In one case of strongly threatened abortion, venesection and opium were used, followed by chloroform, with the best results. During about a fortnight, opium and chloroform were used as occasion required, and the patient, who had aborted at the same period the year before, was carried on to her full term. The child was perfectly healthy. In many of these cases, the cause of irritation is extraneous to the uterus, and by controlling this irritation, we ward off its reflex action on that organ. Besides this, a profound state of anaesthesia does, to some extent, control the uterus itself during labor at the full period ; much more, then, would it be likely to do so, when the uterus is unprepared for normal spontaneous contraction. Labor. — On the use of anaesthesia under this head, we have not been furnished with much material for communication, only about nine cases having been reported to us. In these, the results were very favorable. In two, there was retention of the placenta, but, in the other cases, it was expelled so readily, as to prove the complica- tion to have been purely accidental. The uterine contractions appeared to be temporarily suspended, when the anaesthesia was very profound ; but they soon returned in full force, as the patient emerged from this condition. When the pains 194 TRANSACTIONS OF THE MEDICAL SOCIETY OF VIRGINIA. occurred rapidly, and with little force, the intervals were lengthened, and the pains became stronger under the influence of chloroform. It was remarkable, that during a moderate state of anaesthesia, the patient unconsciously made the usual efforts auxiliary to the uterine contractions. In two or three instances anaesthesia was induced towards the close of labor, in others when the os uteri was ascertained to be fully dilated, and was then maintained during the remainder of the process. There was one particularly beneficial effect observed, viz : a remarkable de- gree of relaxation of the soft parts at the outlet of the pelvis. The peringeum yielded with such facility, that the last stage of parturition was accomplished almost without obstruction. In one instance of protracted labor, chloroform was used to enable the patient to obtain repose, which she greatly needed, after which ergot was administered, and when vigorous contractions were pro- duced, chloroform was again resorted to with the happiest effect. In several instances, the child was delivered and dressed without the least knowledge on the part of the mother of what had occurred ; indeed, in two instances the mothers positively denied the children to be their own when first presented to them. The children were as vigorous as usual. From the effects observed on the occasions reported, we feel autho- rized to recommend these agents on other occasions when their effects are evidently indicated, viz: severe colic, with or without invagina- tion of the intestines, taxis for strangulated hernia, surgical diagnosis of injuries, instrumental labor, manoeuvres in case of malposition of the foetus, puerperal convulsions, &c. Comparison between Chloroform and Ether. — The details under this head are rather meagre. Comparative strength. — About thirty drops of chloroform have fre- quently produced a transient state of anaesthesia sufficient for the ex- traction of a tooth, but no case is reported, in which less than £ oz. of ether was used for the same purpose. Now one drachm of chloro- form contains 120 drops. To produce this transient effect, therefore, one part of chloroform was equivalent to about sixteen parts of ether. In order to produce more profound and prolonged anaesthesia, one part of chloroform was equivalent to about six parts of ether. Comparative effects. — The taste and odor of chloroform was much more agreeable than those of ether. Respiratory o?-gans. — Ether was much more irritating to the air pas- sages during the first inhalations. For this and the previous reason, patients made greater resistance to its administration. Nervous system. — Ether was much more stimulating than chloroform. It sometimes produced a high state of delirium, with a disposition to do violence to others. Chloroform occasionally produced excitement, with a disposition to resist control. Ancesthesia was more persistent when induced by chloroform. This point, however, was not fully established. Comparative efficiency. — Ether failed more frequently than chloro- form. Its prolonged administration failed in two instances to pro- REPORT ON ETHER AND CHLOROFORM. 195 duce complete anaesthesia in children. In one of these, chloroform was used on the following day with prompt and complete success. Modes of administration. — Those usually adopted were with an in- haler, a cambric handkerchief, a cupped sponge, a sponge wrapped in a handkerchief or napkin, and a sponge attached to the middle of a piece of oiled silk. The neatest form of an inhaler which we have examined is that called Rushton's. It is composed of a flat glass bot- tle capable of holding about a half pint, having a mouth-piece of suf- ficient size to cover the lips. At the bottom is an opening for the ad- mission of air. A sponge is introduced through the neck, which is contracted, so that the sponge must be compressed to pass through it. The sponge remains in place very well, and is kept from contact with the face. A fresh supply of the agent may be dropped in with- out removing it from the patient. The objections to this instrument are : 1st. The nostrils are not inclu- ded in the inhaler. The patient may, therefore, close his mouth, and breathe through his nose, thus avoiding the act of inhalation entirely. One of the committee was obliged to lay it aside, owing to this cause, the only time he tried it. 2nd. Although it is more portable than some other forms, it is inconvenient to carry, and cannot always be at hand. 3rd. Its brittleness. The sponge answers very well, but it is not always at hand. The cambric handkerchief may nearly always be procured, and may be used advantageously in every case. It should be placed in the hand and folded in a cup shape, in the bottom of which the agent should be poured. By enclosing a sponge, we have a better reservoir for the agent than we have with the handkerchief alone. The next plan we believe to possess some advantages over every other, and we therefore describe it more minutely. A sponge, large enough to hold about a half ounce of chloroform, is loosely stitched to the middle of a piece of oiled silk about six inches square. The silk lies loosely over the face and under the eyes, and allows the air to enter under the lower edge, which must be raised, if it fit too closely about the chin. When it is not in use, the oiled silk is to be wrapped about the sponge, to prevent evaporation, and it is then ready to be re-applied. Its advantages are, 1st. The eyes of the patient are protected from the vapor, which is apt to irritate them. 2d. The operator is protected. The other usual modes leave him ex- posed to considerable annoyance from the vapor. 3d. It can be readily prepared, and is cheap and portable. 4th. It economizes the agent used. One of the committee, who has used it frequently, has added a tri- angular piece of leather larger than the nose. This is stitched to the oiled silk, and to it the sponge is attached. The leather, when laid over the nose, keeps the sponge from touching the nostrils or lips. The evaporation is slower from this instrument than from the hand- kerchief, consequently the effects are produced more slowly, and for this reason more advantageously. This method was originally published, in the Buffalo Medical 196 TRANSACTIONS OF THE MEDICAL SOCIETY OF VIRGINIA. Journal and Review, by Dr. Geo. M. Burwell. He used it in mid- wifery cases, with a sponge holding a drachm. For the purpose of noting as accurately as possible the amount used, one of the committee is in the habit of keeping the chloroform for immediate use, in a flat, graduated one ounce vial, which we would recommend for general use. It is satisfactory to the operator to know the amount used, for reasons similar to those which cause him to keep himself informed of the amount of any other medicine, which he may administer. It enables him to produce the desired effect with more accuracy, and to give the same quantity to the same person. Rules to be observed in the Administration of Anesthetic Agents. 1st. Examine the quality of the article used. Ether should be care- fully prepared for the express purpose of inhalation. Chloroform should be procured only from some factory of established reputation. 2d. Examine the condition of the "patient. We consider the follow- ing conditions as contra-indicating the use of anaesthesia : Organic dis- ease of the heart, by which its strength is greatly impaired ; for instance, softening and dilatation. We would fear, that in such a case, a greatly enfeebled organ might cease to act under the influence of a powerful sedative. Disease of the lungs, producing considerable loss of sub- stance or extensive tubercular deposit, by which the supply of oxygen to the system is greatly diminished. In these cases we would fear, that the patient might be asphyxiated by lessening suddenly the sup- ply of air, already insufficient for the healthy performance of the vi- tal functions. A tendency to apoplexy. In such a case we would ad- vise either that these agents should be abstained from altogether, or that their use be premised by blood-letting. The congestion of the vessels of the head, together with the sensations experienced just be- fore anaesthesia occurs, indicate some degree of cerebral congestion, which, superadded to that already existing, might be followed by dangerous consequences. • 3d. Place the patient in either the recumbent or reclining posture. The vapors of ether and chloroform being heavier than atmospheric air, in this position they gravitate towards the mouth and nostrils, and thus a smaller quantity is necessary to produce the effect. When the patient becomes perfectly relaxed, an upright position cannet be maintained without support, and if the operator have no assistants the patient may fall from his seat. 4th. Avoid, if possible, administering these agents when the sto- mach is full, for they will then almost inevitably cause profuse vomit- ing, with protracted nausea. This will greatly delay anaesthesia, and seriously embarrass the operator. Strong efforts at vomiting increase the existing cerebral congestion, and often produce severe headache. The patient should be directed to avoid his usual meal preceding the inhalation, or the operator should select his time when the stomach will be empty. 5th. Attend to the admission of air during inhalation. This we be- lieve to be the most important precaution requiring our attention. If REPORT ON ETHER AND CHLOROFORM. 197 the vapor be inhaled in a very concentrated state, it will produce coughing and a sense of suffocation ; the act of respiration will be temporarily suspended, and the patient will run the risk of being as- phyxiated. 6th. Secure complete anaesthesia before commencing a surgical ope- ration, and maintain this condition, by repeating the inhalation as often as may be necessary during its performance. For this purpose, as in the employment of other remedies, pay more attention to the effect pro- duced than to the quantity used. Inattention to this rule may cause the patient to be in a worse condition than if anaesthesia had not been attempted. If this state be incomplete, he is deprived of self-control, and left under the full influence of the reflex system of nerves, when he will be more restless than in a state of perfect consciousness. Chemical composition of ether and chloroform. — In order to the com- pleteness of this report, we subjoin the following remarks : These agents belong to two series of bodies, distinguished by hypothetical radicals, each of which is a hydro-carbon. The radical of ether, called ethyl, consists of four equivalents of carbon, and five equiva- lents of hydrogen, represented by the formula C4 Hs. The radical of chloroform, called formyl, consists of two equiva- lents of carbon and one equivalent of hydrogen, represented by the formula C 2 H. Ether consists of one equivalent of oxygen combined with ethyl, and may be termed oxide of ethyl. Chloroform consists of three equivalents of chlorine combined with formyl, and may be termed perchloride of formyl. The chemical formula of ether is C4 Hs O. " " chloroform is C2 H CI 3. The specific gravity of ether is 0.720 " " '.■■«■■* chloroform is - 1.48 It is reported to have been obtained as high as 1.5 Ether is a highly inflammable substance. Chloroform is not inflam- mable. We should be cautious, therefore, when administering ether, not to bring a lighted candle near the patient, lest the vapor should take fire. This risk does not occur when chloroform is used. We learn that the only "preparation of chloroform in use in this city is obtained from the factory of Messrs. Powers & Weightman of Phi- ladelphia, whose high character is a guaranty of its purity. The quality must, therefore, have been generally uniform. This fact is of importance, as it enables us to ascertain with more certainty the causes producing the variety of effects noticed. On one occasion, a strong chlorine odor was observed, and on examination, it was found that the patient had sent a vial which was not clean. No doubt the impurity had caused a decomposition. From the facts which we have presented, we deduce the following propositions : 1st. Of nearly fourteen hundred instances reported, in which anaes- thesia has been produced, not one has occurred in which either a fatal or permanently injurious consequence has been proved to have re- sulted. 23 198 TRANSACTIONS OF THE MEDICAL SOCIETY OF VIRGINIA. Note. — This proposition is the more remarkable, when it is recol- lected, that the period embraced in this report extends over the entire history of the use Of anaesthetic agents in this city since their introduc- tion ; that their early use was necessarily to a great extent empiri- cal ; and that a large proportion of cases occurred in the practice of those who were not physicians, and of whom we may say, with- out disrespect or disparagement of their professional skill, that they were less competent than physicians to discriminate between those who were and those who were not suitable subjects for the ad- ministration of anaesthetic agents, or to judge of the physiological effects produced. We believe that such a proposition could not be maintained in regard to any other of the most powerful agents of the materia medica. 2d. That on every occasion on which it is desirable to use anaesthe- tic agents, we may do so with confidence, observing proper precau- tions. 3d. That chloroform is preferable to ether, and is equally safe. We would compare its advantages to those of the alkaloids, quinine, mor- phine, &c, over the bulky and often nauseous substances from which they are derived. 4th. That in surgical operations the patient is not only saved the cruel agony which has hitherto been inseparable from many of them, but is in a more favorable condition for their successful performance. 5th. That the process of natural labor is facilitated by anaesthesia. 6th. That in some cases of a purely medical character, these agents furnish a most valuable resource to the physician. 7th. Finally, when we consider the extensive application of these agents, the diminution of suffering and the preservation of life which they have effected, and the relief from embarrassment to the operating surgeon which they afford, together with their safety, they deservedly rank among the most valuable resources of the healing art, and their discovery marks an important era in the history of medical science. All which is respectfully submitted. JAMES BOLTON, M. D. C. BELL GIBSON, M. D. JOHN A. CUNNINGHAM, M. D. WILLIAM W. PARKER, M. D. Erratum. — In the table on page 182, read, instead of the numbers under the correspond- ing columns: Physicians' report, ... Dentists' report, ... 729 655 Males. Females 237 1(33 492 492 THE VAPORS. 199 For the Stethoscope. The Vapors. There are few persons so fortunate, or so happily constituted, as not to be liable at times to feelings of depression, bordering on melan- choly. For. as has been remarked, those who seem most buoyant in public, are often in other moments the most prone to despond. All, however, should endeavor, as far as possible, to attain a cheerful frame of mind. It is somewhat difficult to determine the exact point which separates the mere state of ordinary low spirits in the sane, from the morbid condition of mind and pain to which, from the most ancient times, the epithet melancholy has been applied in a technical sense. The very closeness of this connection, indeed, is such as should induce a habitual struggle against yielding to any emotions of the kind. Perhaps, apart from delusions which do not necessarily ac- company insanity, at least in a marked form, two of the most charac- teristic symptoms, separating it from ordinary depression, and con- stituting melancholy considered as mental derangement, are the pre- sence of nervousness, and a long continuance of the feeling involved, with naught in the nature of an adequate external cause for such a psychological phenomenon. However different the two conditions may be, a proneness to the one should be carefully avoided as cer- tainly apt to lead to the other. So doubtless too. in a measure, the means employed to dissipate the mild or precursory symptoms of melancholia and hypochondriasis, if habitually adopted, would serve to neutralize the action of low spirits. Philosophical considerations present themselves to almost every one, in demonstration of the groundlessness of feeling too deeply the ills, whether fancied or real, of this mortal life. But alas for us ! The path of history is strewed with the wrecks of altars raised to principles fondly deemed everlasting, but which now serve only as subjects of curiosity, or materials to construct other theories as fleeting and transitory as they. Still we may allude to a few considerations that almost by their very triteness fail in exciting a practical atten- tion on the part of individuals, and which yet, it seems likely, should have the effect, when duly digested, of diminishing the intensity of a painful inquietude. Thus, take many of those who are victims to lowness of spirits, and let them compare their situation with that of a multitude of persons, both now in existence, and also of those long buried beneath the lapse of centuries, and they cannot but perceive that their lot is endowed with far more of the elements of comfort, than occurs to a vast number of their fellow-creatures, whose portion nevertheless has not been unhappiness. Again, if there be real mis- fortune to cause feelings of despondenc}^, do we not all see how fleet- ing are alike both earthly sorrows and earthly joys. Of course too, in the deepest night of affliction, religion points aloft to the solemn stars, shining above all the storms and clouds of this world, and beaming on radiantly and undimmed forever. So too, the providence of God, as seen in all things, should be soothing to the grief- worn — that eter- 200 THE VAPORS. nal substratum to the universe, of whose existence they are fully con- scious who have faith, " And hear at times a sentinel, That moves about from place to place, And whispers to the vast of space, Among the worlds, that all is well." [In Memoriam. Although reflections like the above, as it is with arguments against the delusions of the insane, usually fail in producing any consider- able effect, the depressed in spirit would do well to bear them in re- membrance. Such conclusions may be looked upon as the judgment of the thoughtful in the long line of ages, the experience of the thinkers in all time. But each epoch has its own separate experience, and the unusual degree of investigation into the symptoms of insanity, at this date, has elaborated opinions of importance in this regard. Two of these, which we deem plain inferences from facts concerning insanity, traced by physicians of lunatic asylums and other observers of the disease in point on a large scale, seem worthy of mention. We estimate a habit of self-control as very essential to a peaceful and healthy state of mind in this world. We are satisfied that a num- ber of insane persons owe their malady to a want of self-government. The inculcation of this in childhood, to the mind so docile and pliant at that period of life, is especially necessary — as the twig is bent the tree will grow. And if an early vigor is imparted to the youthful mind, by teaching moderation, by a constant endeavor to produce a balance of power in the various mental attributes, then may the storms of life spend their fury in vain upon an individual who is so fortified against them. In Virginia we are accustomed to look upon Washington as the most exalted character that is found on the pages of history : and amongst the qualities constituting the greatness of this illustrious man, no peculiarity is more striking than the complete mastery which he held over all his feelings and emotions, and the ge- neral equilibrium which reigned in all his faculties. If the hopes and associations be fixed on any object in life, whether it be wealth or am- bition, or love, and this darling end be placed apparently beyond the reach, the ill-balanced mind is apt to fall precipitately into the dark abyss of insanity. Moreover, the mere habitual yielding to gloomy thoughts and feelings at last causes these to be persistent, when, if resolutely striven against, they would have been only temporary ; for it is the nature of every mental trait to be increased in strength by exercise. Even, indeed, when a sufferer becomes actually insane, we often witness the internal conflict which he undergoes in resisting the sway of delusions and morbid feelings. It is in truth far more ad- vantageous in managing the insane, to encourage them to use all their efforts in this line of action, than to contend against their false ideas by a logical discussion. Analogous exertions are both feasible and proper on the part of the sane; and it is just as requisite for those prone to them, to refrain from giving way to the predominance of som- bre ideas and feelings, if they would avoid the great calamity of an unsound mind, as it is for the victims of intemperance or the other THE VAPORS. 201 appetites to refrain from such excesses, if they seek to avoid a similar fate. In the treatment of mental alienation, as novv-a-days everywhere pursued, one of the leading measures consists in bodily and mental employment. The particulars into which these two heads may be divided are boundless in number, and have been frequently discussed, sometimes with direct reference to their comparative value and utility. The great principle involved is, however, throughout the same — being to keep the mind so occupied that the morbid feelings and delusions are effaced through inaction. In lowness of spirits, this identical course is to be pursued. Doubtless for such individuals some avoca- tion or employment, naturally congenial to them, will prove most suit- able ; but let them be occupied in some mode, whatsoever it may be. If, perhaps, a man were to seek that condition of things which was calculated to render him most happy, it would be found in a conti- nuous, though not too laborious occupation, in some pursuit in which he took great interest. But even if there be a disinclination to all sorts of occupation, and even to amusements, and although the individual may be wealthy, still it would be the best remedy for a causeless de- pression of spirits, steadily to pursue a fixed object requiring action and thought, in order to attain the end proposed in that relation. . Aber- nethy's counsel to a nervous and dyspeptic lady, was: "Dismiss your servants, madam, and make your own beds." And Burton's wondrous volume, the "Anatomy of Melancholy," concludes with a da capo of advice to the following effect : " Only take this for a corol- lary and conclusion, as thou tenderest thine own welfare in this, and all other melancholy, thy good health of body and mind, observe this short precept, give not way to solitariness and idleness — ' be not soli- taty, be not idle.' " In certain cases of mental disturbance, in which there is an unaccountable nervous distress and agony of mind, Dr. Bell, an accomplished superintendent of the insane, observes, that " the restraints, discipline, and interdiction from friends of an asylum, or of a sea-voyage, are pretty sure to effect a recovery." Not unfrequently we find low spirits distinctly connected with im- pairment of the physical health. In this event medical means will sometimes have a good effect; so on the other hand the mind, even when strictly speaking undiseased, may prey upon the body. We believe, indeed, that these circumstances, though acknowledged in the main, are yet frequently overlooked in details, and occasionally to the disadvantage of the individual concerned. In a trip to a watering-place the mind is pleasantly engaged ; various cares are laid aside ; there is nothing vexatious to disturb the psychical tranquillity ; the change of scene, and the many new objects prevent an indulgence in gloomy reflections, by their pre-occupation of the mind, and this, reacting on the body, causes it also to recover from its ailments. We are inclined to think that, per se, a pleasant sensation is of service to both the men- tal and physical economy conjointly. Indeed, perhaps, effects in themselves pernicious to a certain degree, from the use of certain articles of diet, are counterbalanced by the pleasant sensations felt in the system generally. Thus an individual comes to his home at the 202 THE VAPORS. evening hour, wearied with a day of toil, and perhaps harassed with mental uneasiness. Refreshing to him under these trials is the influ- ence of tea or coffee ; any evil effect on the nerves is thus, perhaps, compensated for by the soothing power over mind and body, and their mutual reaction for the good of the whole animal frame. This idea may also apply measureably to tobacco ; but it will not answer to extend the theory too far. For the continuous effects of these agents on the nervous system, if they are used for a long time to excess, must prove highly deleterious. And we may here remark, that nothing can be more erroneous, than for those affected with low spirits to resort to nervines for the purpose of relieving their despon- dency. Apart from the permanent ill consequences in the end, there is always a scate of depression immediately following the preceding exhilaration. This remark applies to every nervine, for all the ex- hilarating substances employed by man are but letters of the same alphabet, whether they are entitled stimulants or sedatives. There is no intrinsic or essential difference in this aspect ; for example, between tea, coffee, alcohol, opium, hachish, chloroform and tobacco. He who becomes an abject slave to any one of these, realizes the an- cient legend of Faust's compact with the demon, to resign his hopes of everlasting bliss, for temporary pleasures of an exciting character. If there be any circumstances justifying the use of such agents in these cases, it is the employment of those nervines so calculated to act, in order to procure sleep. But even here great caution is requisite lest that become a habit, which in the first instance was so pleasant in itself, and that besides relieving pain perhaps, procured rest and all its attendant refreshment, in place of a previous general malaise. Most diseases are brought on b3r improper indulgence during health, or want of due carefulness against the invasion of a malady. Per- sons when in health, finding that they can neglect hygienic rules for a long period without evident detriment, are led to imagine that their experience runs contra to supposed facts deduced from them. But oftentimes they are but sowing the seeds of disorders which ultimately burst forth in an aggravated form. They who would property enjoy life, should strictly attend to these pi-inciples, unless, indeed, they pre- fer the error of passing " a short life and a merry one." Those sub- ject to low spirits of course come within the general category. There are, however, a few precautions, which seem to demand particular care on their part, and to which, moreover, the attention of their friends should be directed when their habitual tristesse seems on the verge of terminating in actual insanity. Dr. Brigham observes, that "notwithstanding strong hereditary pre- disposition, ill-health, loss of kindred or property, insanity rarely re- sults unless the exciting causes are, such as to occasion loss of sleep. A mother loses her only child, the merchant his fortune — the politician, the scholar, the enthusiast, may have their minds powerfully excited and disturbed — yet if they sleep well, they will not become insane." In order to secure this blessing, active exercise is the chief resource, should it be feasible. Early rising and retiring are also advantage- ous ; and the individual should avoid excitement at night, and the in- THE VAPORS. 203 fluence of perplexing thoughts. He should endeavor to turn his mind, on retiring to bed, from any present idea creative of anxiety, by fixing his thoughts on scenes in the past, or the consideration of other per- sons rather than himself, or on expected events in the future, which are attended with hope. " Building castles in the air" may also be resorted to, and counting a large number is an old plan in this regard. The educated have also a resource here in directing the attention to matters which they have read, or in endeavoring to recollect snatches of poetr}', or in testing their remembrance of historical and scientific truths. In some cases where the rest is broken, rising from bed and washing the face and hands in cold, or bathing the feet in warm water; or the use of perfumes will be of service. As a last resort, and un- der peculiar circumstances, the cautious employment of nervines may be adopted. Dr. Macnish, in his work on the " Philosophy of Sleep," says, the body should be brought to a medium temperature before re- tiring, and that, as a general rule, a person who eats nothing for two or three hours before going to rest, will sleep better than he who does ; and he approves of the habit of the Chinese, of brushing their teeth before lying down. Another precaution to which the nervous and melancholy would do well to attend, is, being careful as to the condition of the alimentary canal ; for keeping the bowels open, as holds good with respect to other processes of nature, diet and exercise are preferable to medi- cines. Especially if there be a dyspeptic tendency, it will be often found beneficial to substitute the Graham biscuit for all other kinds of bread. In some cases of low spirits, a mild laxative might doubtless be used occasionally with advantage. In melancholy derangement, purgatives have been employed from the most ancient times — less now perhaps than formerly. Pliny asserts that the black hellebore was first discovered at an early period, by Melampodius, and that through its action he cured the daughters of the king of Arcadia; and in an- cient times those laboring under mental derangement were sent to Anticyra to be purged, this plant growing very abundantly on that island. With regard to bathing, Dr. Winslow makes the following remarks: " The state of the mind is closely dependent on the condition of the cutaneous secretion. I should recommend those who are subject to mental depression — hypochondriasis, the vapors, ennui, or by what- ever designation it may be termed — to try the effect of systematic bathing. I feel assured that, in many instances, violent attacks of in- sanity may be warded off by the use of the warm or cold bath. In cases of cerebral irritation, evidently the result of a tendency to vas- cular excitement, bathing the head regularly every morning with cold water, or vinegar and water, will be followed by great benefit to the health of the body as well as the mind." J. M. G. 204 METTAUER ON PUERPERAL FEVER. A case of Puerperal Fever successfully treated — with Observations. BY JNO. P. METTAUER, M. D., L. L. D., OF VA. The case of puerperal fever about to be reported through this pa- per, occurred with an exceedingly delicate female servant, aetat. 25 years, who had borne children very rapidly, having had five, includ- ing the one born immediately before this attack. Her previous labors were not distinguished by anything very remarkable, and the recove- ries from them were generally as speedy as could have been expected with one naturally delicate, and who was rendered more so by fre- quent pregnancies and childbirtbs. The pregnancy immediately pre- ceding this attack of childbed fever, in its early periods, was similar to the former ones. In the latter months of it, however, and particu- larly the last two, the woman suffered more or less from fever, espe- cially of evenings, restlessness, thirst, loss of appetite, irritable bow- els, debility, abdominal tenderness, especially near the close of ges- tation, and the most hopeless despondency. When labor set in, the woman was a mere living skeleton — the most emaciated person conceivable, to be struggling with the throes of childbirth. The labor continued about 16 hours, and was not more distressing than her former ones, with the exception of the soreness of the soft wall of the abdomen, which each uterine contraction, to- wards the close of labor, rendered very distressing. When the mem- branes gave way, and the liquor amnii dashed over the midwife's hands, the temperature of it was so high as to impart the sensation of a " scalding heat," as the midwife expressed herself, and actually greatly alarmed her. The woman, too, complained of the unusual heat of the waters. The midwife informed me also, that when she passed her hand into the cervix, for the purpose of dislodging the placenta, its surface was exceedingly hot, more so than in any case in which she had ever officiated before, and her experience had been considerable. This condition of the liquor amnii, as represented by the midwife, was not new to me, as I had met with it in some seven or eight cases ; and I have now and then found the reverse to be its condition, as well as of the uterine surface, which I have found so cold as to impart a decided and exceedingly unpleasant sensation of coldness even during the heat of summer. The case in question occurred in Sep- tember, and during very warm weather, so that the midwife could hardly have been deceived by reason of her hands being cool at the time the waters were discharged upon them. These remarkable de- partures of the temperature of the liquor amnii and uterine surface from their ordinary conditions, I have always esteemed indications of danger, and a strong liability to puerperal lever ; in several instances they have been succeeded by that terrible disease before I adopted my prophylactic treatment of childbed fever — a paper on which subject I contributed to the January Number of the " Charleston Medical Journal and Review for 1851," an exceedingly well conducted and valuable journal. METTAUER ON PUERPERAL FEVER. 205 On the fourth day after delivery, nearly 100 hours from the time of its completion, I saw this woman for the first time after the attack of puerperal peritonitis commenced. I learned from the family, that a chill ushered in the disease, which occurred about 13 hours after de- livery, and was soon succeeded by violent febrile reaction, pain of the inferior portion of the abdomen, thirst, nausea, and some tumefac- tion of the abdomen. I was informed by the midwife, that the abdo- men did not subside, as is usual after delivery, but remained full and rather puffy. Very soon after febrile reaction set in, the abdomen became more tender under pressure during efforts to turn the body or to cough ; and the after-pains, which the case was supposed to be for nearly three days, greatly augmented the sufferings of the woman, as well as the peritonitis. I could not procure from the family, nor from the suffering woman, who was too ill when I arrived to give me a satisfactory account of the case, after the pains greatly augmented in violence. I learned that the lochial discharge ceased about 20 hours after delivery ; that the pain was constantly confined to the region of the uterus and inferior part of the abdomen ; that urination was at- tended with difficulty early after delivery, and for the last day before I saw the woman, was impracticable ; that the bowels had never been properly evacuated, and were still constipated ; and that the abdomen had been swollen to its present enormous size for more than forty hours. I found the whole abdomen greatly tumefied, painful and exceedingly tender under the slightest pressure. Even the bed-clothes resting upon it, or the least change of posture, caused intense suffering. The pulse was greatly, nay, fearfully accelerated, exceeding in frequency 160 beats in a minute, was concentrated, tense and resisting; the respirations were hurried, exceeding 45 in a minute ; and the breath- ing was laborious, attended with frequent sighing, and chiefly thoracic ; the skin was hot and dry; there was incessant and most tormenting thirst ; the eye was unsteady, and expressive of the greatest suffering ; the position of the body was constantly dorsal, with the legs flexed on the thighs and drawn up ; the tongue was moist, but covered with a whitish fur; the bowels were constipated, yet there was a frequent desire and repeated ineffectual efforts made to evacuate them ; there was retention of urine ; intense internal heat was constantly com- plained of; the lochial discharge had disappeared in a very great degree, and in its place a sanious, dark, offensive discharge appeared ; the breasts were flabby and pendulous, and without the slightest ap- pearance of a disposition to secrete milk; the vagina was hot and dry ; there was almost a constant disposition to eructate, which caused the woman much distress in fruitless efforts to expel air from the sto- mach ; there was almost incessant moaning as well as great restless- ness ; the mind at times was wandering, bordering on delirium ; the most perfect disregard and want of concern for the infant was con- stantly manifested by the woman ; there was a fixed aversion for food ; and for three days and nearly four nights the eyes had not been closed in sleep a moment. The treatment adopted in this highly interesting and threatening case was antiphlogistic, decisively and vigorously carried out in practice, 24 206 METTAUER ON PUERPERAL FEVER. regarding the disease, as I have always done, inflammatory in the highest degree, especially in its early stage. My first aim was to en- feeble the organs of the active circulation so decidedly as to arrest the inflammatory process at once, and to protect the inflamed peritoneum, uterus, &c, against disorganization. To accomplish these ends, I first employed blood-letting from the arm, previously placing the woman in a semi-recumbent posture, and detracting the blood through a large, free orifice, until fainting was induced. In this manner sixty ounces were drawn at the first bleeding, before fainting could be produced. The effect, however, was decisive — a complete syncope came on, which continued fully two minutes after the woman was placed completely horizontal. Indeed, consciousness did not fully return for ten minutes, and from the commencement of the swoon, a copious and general sweat made its appearance, that continued more than three hours. The condition of the pulse was remarkably changed by the bleeding ; its frequency was suddenly reduced from 160 to 120 pulsations in a minute, and was softer, more expanded and regular in its heat. The respiration and abdominal pain were also greatly ameliorated. Twen- ty-three respirations instead of forty -five were now only to be enu- merated in a minute. The countenance was less anxious, and the woman expressed herself as greatly relieved in all respects. With- out a moment's delay, an emetico-cathartic was administered, which, to save time, had been previously prepared, consisting of half an ounce of senna, one drachm of jalap, two ounces of Epsom's purging salts, one drachm of aniseseed, infused in a half a pint of boiling water for a few moments, and then gently boiled until the quan- tity of the menstruum was reduced to a gill. To the strained fluid, while pretty warm, three grains of tartar emetic were added, and the preparation thus formed was administered at one dose. The woman was now slightly turned on the right side, so as to cause the gastric contents to gravitate to the pyloric extremity of the sto- mach, both to prevent the rejection of the medicine, should early emesiatake place, and to quicken the passage of it into the duodenum, and its operation as a cathartic. The change of position of the wo- man's body was effected without much difficulty, and with very little pain, and it was maintained until vomiting commenced, which took place nearly three-quarters of an hour after the dose of medicine was administered. As soon as the purgative had been given, and the position of the body properly arranged, fomentations were emplo}red over the entire abdomen. These were used as hot as they could be borne, and were repeated every fifteen minutes. In the mean time an active enema of strong salt water was prepared, consisting of three heaping table spoonsful of the chloride to the pint of hot water, which was injected into the rectum, of the proper temperature, immediately after the commotion from the first vomiting subsided. The enema was retained, contrary to expectation, nearly twenty minutes, and pretty soon after its action commenced the vomiting was renewed, the two remedies acting simultaneously, producing artificial cholera morbus ; and this state of cathartico-emetic action commencing with the operation of the enema, continued during the action of the purga- METTAUER ON PUERPERAL FEVER. 207 tive, which commenced its operation in an hour after the administra- tion of the enema. I have never witnessed, in the whole course of my professional life, such copious products by vomiting and purging, as were yielded by those agencies in this case. The quantity ejected from the stomach was so enormously large as actually to astound me, and yet very little in the way of food or drinks had been taken into it from the commencement of the attack, as I was assured by the family and nurse. The same was the effect with the alvine discharges ; they were copious beyond anything I have ever seen in like cases. The evacuations from the bowels consisted of large quantities of faeces, in- termixed with crude, undigested alimentary substances, and sero- mucous matter. Four evacuations from the bowels were procured by the enema and internal cathartic, and two of them were very copious, while two were free, but not unduly so, and feculent. Vomiting dis- charged considerable quantities of bile mixed with flakes of mucus, and an extremely dense, tough, and ropy semi-fluid of a mucous cha- racter. It could be perceived at the close of vomito-cathartic commotion, that the tumidness as well as the tenderness of the abdomen had considerably subsided. The woman was now able to turn in bed, and otherwise change the position of her body with less difficult}'- and suffering, and she certainly complained less of pain, and stated that she felt less of it. The fomentations were laid aside after the third alvine evacuation, and the whole abdomen freely rubbed with pure or mixed spirits of turpentine made a little warm, and then covered with a blistering plaster securely confined with a suitable bandage. At this period the sweating had considerably abated, but the skin was still moist, though unequally so; and whenever quite dry was manifestly unduly warm. The pulse, too, was becoming more active and strong, and the woman complained of some return of abdominal pain, and was more restless. The orifice was again opened — though, I confess, with fearful misgivings, by reason of the alarming syncope from the previous bleeding — first elevating the woman's head and trunk, as far as could be done without causing pain, to enable me to avail my- self of the horizontal posture suddenly, should fainting again follow bleeding. I now detracted twenty-three ounces more of blood promptly, which produced faintness, but not complete syncope ; and as soon as the woman was placed horizontal, the sweating was re- newed. This bleeding reduced the force, as well as the frequency, of the pulse most decisively ; and in half an hour after it, the woman fell into a quiet, sound slumber, which continued until she was aroused by the drawing of the blister, supposed by the nurse to have been of three hours duration. The drink chiefly used was cool " pine-tops tea," and the woman was urged to take it freely, which she willingly did. Pounded ice and iced water were also allowed, and freely used as gastric refrigerants, as long as the internal sensation of distressing heat and the thirst continued. The introduction of ice into the sto- mach, coarsely pounded, effectually and most gratefully relieved that distressing symptom, internal heat. I also applied ice to the os uteri and cervix, as well as to the dry and hot vagina, by introducing pieces, 208 METTAUER ON PUERPERAL FEVER. quite up to the os tincse, of proper size and form to fill the vagina, as long as undue heat of those parts continued. This last was a most grateful and efficient remedy, and co-operated beneficially with gas- tric refrigeration. As soon as the woman was fully awake, I administered twenty grains of calomel, with one-fourth of a grain of tartar emetic, mixed in dry brown sugar, washed carefully from the mouth with pine-tops tea, and swallowed ; and had her placed partly on the right side and back, for the reasons already stated. In two hours after the calomel was taken, an active enema of strong saltwater was administered, which, being retained some five or six minutes, procured a slight feculent dis- charge from the bowels ; and it excited considerable irritation about the rectum, that caused the woman to complain greatly, for some ten or fifteen minutes, of tenesmus and straining. As soon as the rectal irritation subsided, the blister was examined, and found to be well drawn in every part of its extensive surface. It was indeed an ex- tensive as well as perfect blister : fully sixteen ounces of serosity were discharged from the blisters, as they were opened. A dressing of soft cabbage leaves was applied to the blistered surface, which, in a majority of instances, should be preferred as the first dressing, by reason of its softness and lightness. The dressing of the blister, for the first time, took place about the tenth or eleventh hour after my arrival, and the one hundred and tenth of the disease, and in all respects the case had very greatly amelio- rated. Very soon after the dressing of the blister was completed, the woman fell into a soft, quiet sleep, which continued three hours, and would have been still farther prolonged but for the operation of the calomel. The bowels acted freely, and the evacuation was of good consistency, as well as of the proper color of feculence, emitting like- wise the true feculent odor. With the purging from the calomel, the tumefaction of the abdomen began to subside, and its diminution was so rapid as to be almost perceptible. Several times while observing the tumefaction, during a dejection, I imagined that I could actually perceive it to diminish and subside, and yet there was no expulsion of flatulence from the bowels. All pain and tenderness of the abdomen very soon disappeared after the operation of the calomel, and the wo- man expressed herself as entirely relieved. The pulse now was re- duced to 90 beats in a minute, and was soft and expanded. The skin became moist and of the proper temperature. The respirations were reduced to twenty, and of easy performance. From this period there was progressive amelioration in the symptoms to complete recovery, without the slightest interruption. The blister suppurated freely three or four days. There was no necessity for diaphoretics. To prevent constipation, a moderate dose of aloes, rhubarb and jalap, in the form of a pill, was given nightly, which completely answered the purpose. The appetite returned by the twentieth hour after I saw the woman the first time, and by the fortieth was very keen. There was a slight return of the lochial discharge very soon after the calomel ceased operating, which was about 15 hours from my first visit, and it in- creased in quantity until the discharge was quite free for one so feeble. spencer's occlusion of the vagina. 209 On the third day from my first visit, or the fifty-eighth hour after the first bleeding, there was some fulness of the breasts, and a few drops of milk could be pressed out from them. From this time I discon- tinued my visits, requesting, however, that I should be sent for imme- diately, if any thing threatening occurred, or if the convalescence did not proceed regularly ; and I learned some weeks afterwards, that the woman had recovered without any accident, and was quite well except somewhat feeble. Remarks. — The chief importance of the case reported, somewhat in lengthy detail, is connected with the very free employment of san- guineous depletion at so late a period of the disease in its medica- tion ; and perhaps in no other disease but puerperal fever would such apparent ultra, bold or rash treatment have been -justifiable. It was too evident that the case must speedily end in fatal disorganiza- tion of the uterus, peritoneum, and such other organs as might be im- plicated in the inflammatory process, unless its course could be promptly arrested ; and I had in many other cases employed a like treatment successfully, though never in a single instance under cir- cumstances as unpromising. I think it questionable if bleeding alone would have arrested the progress of the inflammation, although its effects upon the pulse, pain, &c, were decisive. The powerful im- pression made upon the gastro-enteritic mucous surface, so soon after the heart and arteries had been profoundly impressed by the enfee- bling operation of bleeding, and on a surface naturally antagonizing the serous, the principal seat of inflammation, was well calculated to produce revulsion from the serous surface, and while secretion was in some degree restored, and the circulation equalizing itself, as mani- fested by the change in the character of the pulse and the perspiring state of the skin. Prompt and decisive bleeding, speedily followed by an active emetico-cathartic, have in numerous instances arrested the course of this fearful and cruel disease in my hands; and I can con- fidently recommend the treatment to my brethren of the country, and especially to those practising in healthy situations. My experience leads me to the conclusion, that puerperal fever is always an inflam- matory affection ; that its tendency is rapidly to disorganize the organs in which it occurs ; that it is not a contagious or communicable dis- ease, and that it can be most successfully combatted by the early adoption and rigid and energetic enforcement of antiphlogistic medi- cation. Prince Edward C. H., February 1851. Occlusion of the Vagina — Successful Operation — followed by Conception and Delivery. BY P. C. SPENCER, M. D., OF PETERSBURG, VA. Mrs. ***, aged 25, -fleshy, Lymphatic temperament, apparently in good health, came under my treatment in April 1846. She sought relief for an extremely distressing state of the genital organs, which had existed seven years. Upon examination I found complete occlu- 210 spencer's occlusion of the vagina. sion of the vagina. When the labia majora, which were perfect, were separated, a firm cicatrix was exposed, which involved and oblite- rated the labia minora, and occupied the place of the natural vagina. This cicatrix was firm and unyielding, and seriously deformed the parts by the contraction it had produced. In its centre was an orifice with firm edges, feeling, when the finger was placed on it, like the bore in the tube of a key. A probe could be passed a couple of inches along the orifice when an obstruction presented itself. No com- munication to the uterus existed, and this lady had not menstruated since the accident which led to the deformity. The obstruction of the vaginal canal, notwithstanding this duct, was complete, and that ob- struction appeared to consist of a firm, white cicatrix. The origin of the mischief could be traced to parturition. From her statement it appeared that she married early — gave birth to an unusually large infant in her 17th year. Her labor was tedious and difficult, and, unfortunately, immediately was followed by alarming illness, which served, by diverting the minds of the attendants, to pre- vent that attention to the state of the genitals, which their tender and lacerated condition required. Sloughing was the result, and accom- panying her recovery was the gradual approximation of the vaginal walls, by adhesive inflammation, ultimately terminating in that condi- tion which we have described. In a short time after her recovery the bloom of health faded from her cheek, she became sallow, and com- plained of great debility. Besides the disease, to be relieved of a de- formity so distressing, the patient was prompted to seek aid from the fear that the long-retained menses might ultimately prove destructive to her health. It appeared that at regular intervals she had every symptom of menstruation, without any external discharge. The case presented some rather novel aspects, and it was evident that a peculiar treatment was required. The vaginal walls were too much distorted, and too much hardness existed in the cicatrix to per- mit of the hope that dilation, by tents, &c. could be effectual. Such a method, to say the least, would have been extremely tedious, if suc- cessful, for only a small sized bougie could be introduced in the ori- fice, and that only for a short distance. The whole mischief seemed to result from the cicatrix, which by its contractions had served to draw the anterior and posterior surfaces of the vagina together, so that the rectum and urethra were nearly approximated, whilst laterally the canal seemed greatly widened. This state of things forced the external labia apart and exhibited the cicatrix, the smooth surface of which resembled the palm of one's hand. Under the circumstances it was determined, with the patient's full consent, to excise the cica- trix. For this purpose, after evacuating the rectum and bladder, the patient was placed on a table in the position for lithotomy, and with the aid of my friend Dr. J. F. Peebles, by whom I was assisted in this novel proceeding, we proceeded as follows : An eliptical inci- sion was commenced, just below the urethra and carried around the cicatrix, very much in the course and position of the internal labia, which, as we have said, had been obliterated or merged into the cica- trix, terminating at the commissura below. A corresponding incision A CASE OF IRRITABLE UTERUS. 211 having been made on the opposite side, the intervening mass was then carefully dissected out, inclining upwards and rather in front. The mass removed consisted of the hard cicatrix, and was two inches wide and two inches and a half deep. This proceeding completed the operation. We found that by it we had obtained a canal in the direc- tion of the womb, nearly three inches deep, at the bottom of which the orifice above spoken of could be felt and easily dilated by the finger. This circumstance, together with the altered character of the imperforation still existing, led to the adoption of simple dilatation for its further removal. For ihis purpose, after cleansing the wound and arresting the bleeding, which was very slight, a sponge tent smeared with wax, of suitable size and length, was introduced and kept in situ by appropriate bandages. The patient was kept on her back and the dressing daily employed, each time using the finger as a bougie, to overcome the bands still existing. Some short time after the ope- ration, we requested her to inform us of any symptoms indicating a return of the catemania : she readily complied, and we ordered an ap- propriate emmenagogue course with the happiest effects ; for at the very next return of her period, much to her gratification, the men- strual flow took place. Gradually a natural mucous surface was formed along the new canal, and in four months from the time of the operation all treatment was abandoned. Our patient was a widow at the time of the operation. She chose to marry, however, a few months after getting out of our hands, and within the course of a year afterwards gave birth prematurely to an infant. Since that time, she having left the state, we have lost sight of her. For the Stethoscope. A case of irritable Uterus of four years standing, successfully treated. Mrs. D. of N. J., about 35 years of age, mother of four children, the youngest five years of age, requested my advice relative to her case — stated she had been a great sufferer for four years ; had been treated by several physicians, who had, by the usual treatment and short confinement to bed, given her temporary relief. No sooner out of bed than a return of the usual distressing symptoms — often find- ing relief by elevating the hips unusually high. There was a con- stant inclination to make water, which she could only do by sitting flat on the bed or cushion over a flat pan. Her sufferings were fre- quently so great, from sitting up or walking, that she was compelled to use large opiates. Menstruation regular, but painful ; constipated bowels or distended bladder alike produced distress. On examina- tion I found the uterus low ; the os tineas a little enlarged, of a carti- laginous feeling; neck but little enlarged, and excessively painful when touched, find portions of the vagina were likewise very sensi- tive. Slight febrile paroxysm in the evening, headach and the pecu- liar feeling of a hair about the tongue. I readily came to the conclu- sion that it was one of the peculiar cases so accurately described by 212 LOOSENESS OF MODERN MEDICAL WRITING. Dewees. I made known to her my opinion, and the treatment she must submit to, as the only hope of relief. To this she readily consented, remarking, " Death would be preferable to a life of sufFerino-." The course of treatment, as recommended by Dr. Dewees, was steadily pursued for seven months ; a rigid diet, cupping over the pubic re- gion, leeching the vagina, occasionally a poultice or blister, mild and soothing injections, and finally a small pessary, and she was enabled to move about the house with much less inconvenience than she had done for four preceding years. It has been some months since I saw her, but I learn she is doing well. R. H. P. Portsmouth, Va. For the Stethoscope. The Looseness of Modern Medical Writing. There is, at the present day, great looseness in much of our medi- cal writing, especially in this country, which is by no means credit- able to the profession, and ought to be corrected. Even in the use of some of our common terms, there is an indefiniteness, which renders the sense obscure, and impairs the value of much which would other- wise be useful. I was particularly struck with this, in reading some portions of the report of the committee on practical medicine, made at the last meet- ing of the American Medical Association ; and in no part more forcibly than in the general conclusion at which the committee arrived, on the subject of the contagious or non-contagious nature of cholera, in the following words : That " cholera is portable, but not contagious ; that it is dependent for its accidental power, rather upon density of popu- lation and personal uncleanliness, than upon any other causes. An atmosphere highly charged with emanations from living bodies seems to be the chief stimulant to the choleric influence. Next to this, the most powerful auxiliaries seem to be habits, passions, and food of a depres- sing character; whilst the influences of ever}^ kind, which usually de- termine the blood to the intestinal surface, give to the diseased- agency its most dangerous direction." In most of this paragraph there is an obscurity and vagueness of language, which makes it difficult if not impossible to comprehend the meaning of the writer. He speaks of the "cholera" being port- able— shewing that he considers it a something capable of being transported to a distance, either, I suppose, in the bodies or clothing of individuals, or in the atmospere within or about vehicles, which go from an infected into an uninfected town or district. He then speaks of " emanations from living bodies,'''' as the " chief stimulant of the choleric influence." This is clearly an admission that these emana- tions contain the genuine cholera poison, how or* from whatever source it may be generated. But what is meant by an atmosphere charged with this poison, in other words, the poison itself, stimulating the choleric influence ? What is this peculiar influence ? Is it intended LOOSENESS OF MODERN MEDICAL WRITING. 213 to imply that there is some principle, apart from the cholera poison, generated or already existing in locations where cholera breaks out, influencing living bodies and bringing them into a condition of suscepti- bility to the action of the poison ; or, that the influence spoken of is the susceptibility itself, generated by some occult cause in bodies sub- jected to its influence ? Or does the writer mean that the language is to be taken literally, and there really exists some undefined material or essence, which he designates as " choleric influence," and which, being stimulated into activity by " emanations from living bodies," be- comes the agent in producing the disease ? That the writer had some definite conception of the meaning he intended to convey by this lan- guage— sanctioned, as it is, by the committee — cannot, or ought not, I suppose, be doubted, but he surely ought to have taken more pains to convey it in a plain and intelligible form to his readers. Towards the close of the paragraph, the writer speaks of the " dis- eased agency" receiving its most dangerous direction from the " various influences which determine the blood to the intestinal surface ;" in- cluding also, doubtless, the stomach. Now, as far as I know or ever heard, this surface is the part to which the disease is in all cases di- rected, whether in its milder or more dangerous form. The language, however, is smooth and pretty ; and, I suspect, the writer jeoparded the sense to the desire to finish off a rotund and flowing sentence. In pointing out the cause or causes of disease, it is not uncommon of late to find the remote or predisposing spoken of as the exciting cause, and the exciting as the proximate. Thus the poison of small- pox is said to be the exciting cause of that disease — marsh miasma of bilious fever, and the presence of a foetus in utero is made the proximate cause of puerperal convulsions, &c. This practice is alto- gether inexcusable, when so little attention is necessary to correct it. It may not be out of place to give a short explanation of the seve- ral links in the chain of causes, engaged in preparing for or bringing on disease, adopted in the early ages of the profession, and not since improved on. They are, the remote or predisposing, the exciting and the proximate. The last might be dispensed with, as it is defined to be the " morbus ipse," and therefore cannot be a cause of itself, but it has been retained by common consent, and is well understood. The office of the remote or predisposing cause is to bring the whole or some part of the system, slowly or rapidly, according to its intensity or the resistance it meets with, into a condition which the old writers called disposition to take on diseased action. The exciting cause then being applied to the part or parts so disposed, the morbus ipse is lighted up, and the three links in the chain thus become complete. B. [The justness of the criticism of B. will be readily conceded by every reader of our medical periodicals. A little more attention on the part of reporters of cases, would make their papers much more valuable. We frequently see communications in the journals, which are nothing more than announcements that the reporter had treated them. If the diagnosis, progress, treatment or termination of a 25 214 MEDICAL DUTIES AND OBSERVATIONS. case is interesting or novel, then the practitioner in whose hands it occurred owes it to the profession to report it — but the report is not worth the room which it occupies, unless the reader can learn from it the points of interest. Writers should study to give briefly, though con- cisely, all the circumstances which could possibly be instructive or in- teresting to a reader. How often, after reading the history of a dis- ease, do we have our curiosity excited on many points of absolute im- portance, but which the writer entirely forgot to notice. These re- marks are called forth by the fact that we have received several re- ports which are valueless, and cannot be published on account of the meagreness of the details, and the absence of facts essential to their interest. Elegance of composition we consider of secondary moment, but accuracy of observation and clearness of description are absolutely necessary in matters of science. — Ed. Steth.] Medical Duties and Observations. Mr. Editor — The possibility of my offering a few suggestions of practical utility to my professional brethren, and particularly the junior members of the profession, induces me to send you a few lines for the pages of your valuable journal. We would then first direct attention to the consideration of the physician's duty on his first visit to a patient. Before instituting any plan of treatment, he should direct his enquiries to the " history of the case" — the sex, age and previous condition of the patient, his or her location and occupation, the degree of nervous impressibility, and susceptibility of the system to the action of medicine, the duration and particular stage of the disease at the time he is called, the con- stitution and strength of the patient, the probability of any modifying influences, giving to the disease a peculiar character, whether epide- mic, endemic, or other agencies that may possibly have exerted a morbific impression upon the animal economy. In the next place he should not forget that, as a general rule, the safest, most philosophic and successful course to pursue, in the ad- ministration of remedial agents, is to treat the disease upon general and scientific principles, practising, according to indications, the vary- ing condition of the patient, and the mildness or malignity of the ma- lady ; that the sanative or curative properties, or rather influences, if medicinal agents are not positive, but entirely relative, and that to effect a cure they must be administered with direct reference to the peculiar circumstances of the case. Hence they may exert a salutary or dele- terious agency, according to the degree of enlightened judgment exer- cised in their employment ; and I would offer the following as a medi- cal maxim, that the indiscriminate employment of remedial agents is the dictate of neither science, philosophy, reason nor humanity, and that only the intelligent, the discriminating and well-educated mind is qualified for the assumption of the responsible duties that devolve upon the practitioner of the " ars divina," or healing art. From the above observations, the deliberate expressions of (I think) enlightened RUSHTON AND CLARK'S COD LIVER OIL. 215 conviction, the deduction may be very logically made as to the light in which I regard every species of empiricism 'end quackery in medi- cine, which is generally suggested and practised in perfect accordance with the promptings which " the love of money" excites, patronized and sustained by the ignorance and blind credulity of the people. In reporting any case for the edification of the profession, the writer should not call any medical authority to his assistance in order to M make up" the diagnosis of a disease occurring in his section of country, but should describe the phenomena as he observes them, and not conclude that, under the modifying circumstances of other locali- ties, it may not present diversified phenomena, indicating a correspon- ding modification of the remediate treatment. In procuring a collec- tion of facts as the preliminary step to the construction of any medi- cal theory, the following rules should be strictly and constantly ob- served : 1. That all the facts be clearly ascertained, introducing none but those derived from rigid experience and close observation, and receiv- ing only such as are well authenticated by the testimony of observers fully competent to judge of their accuracy. 2. That a fair, full and comprehensive view be taken of all the facts connected with the sub- ject, modifying or disguising none so as to make them bear upon a particular theory. 3. That we omit nothing that is essential, and in- clude nothing that is irrelevant or incidental, being careful, at the same time, of the post hoc and propter hoc. 4. And lastly, that we do not admit as facts assertions which are not facts, but mere opinions or gra- tuitous assumptions. Many minds are in the habit of drawing sweep- ing or general conclusions from one or two facts. The statements of such should be received with a great deal of caution, for they are not reliable authors,' being liable to self-deception. In conclusion, I would remark, that an intelligent, free agent should never yield a cowardly subscription to the ipse dixits of any writer, nor float passively in the current of popular opinion. The bold, original, independent mind bursts asunder the restraints of usage and the bonds of fashion, and, like the soaring eagle, proudly mounts above the dogmas and clouds of ignorance and prejudice that enshroud the dependent parasitic mind. In medicine we should have no hobbies, no predilections, no obstinate partialities for this or that remedy exclusively, and inde- pendently of all modifying circumstances and contra-indications. J. L. D. Oalc Grove, Va., February 20th, 1851. Rushton's Cod Liver Oil. Mr. Editor — It seems that in a preceding number of your journal, you gave the results of some experiments made before the Medical society, testing the purity of the different kinds of cod liver oil which are offered for sale in this city — the test used was nitric acid. The result was calculated to cast suspicion upon the purity of that manu- factured by Rushton* Clark & Co. These gentlemen have asked at 216 RUSHTON AND CLARK's COD LIVER OIL. your hands a fair trial, and at your request I have submitted their oil to the test used before the Medical society. The oil was furnished by their agents, Messrs. Purcell, Ladd & Co., and was said to be ge- nuine. 1st. When one part of strong nitric acid was added to five parts of the oil, that portion in contact with the acid assumed a bright red co- lor. Upon being shaken, the whole became of a dark red or brown color. The mixture was then set aside, when, after the lapse of half an hour or more, it assumed gradually a brighter red, and finally re- mained of a deep orange color. This I repeated several times, the oil in every case finally assuming the last named color. 2d. When nitric acid was added to whale oil, or a mixture of whale and cod liver oils, the bright red color, as observed in the experiment with the unmixed cod oil, appeared, but when shaken assumed a black color which it retained. 3d. When nitric acid was added to pure lard oil, and the two sha- ken well, and allowed to stand several hours, the whole assumed a dark clouded appearance. When the acid was added to a mixture of cod liver and lard oils, the resulting color was a much darker red than when the unmixed cod liver oil was used. 4th. When nitric acid was added to olive oil, it became of a light greenish color, and finally, losing the greenish tint, becoming slightly clouded dark. When the acid was added to a mixture of this oil and cod liver oil, the ultimate color was deeper than when the unmixed cod oil was used, intermediate between that produced upon the pure cod liver oil and that upon a mixture of lard and cod liver oils. You may draw your own conclusions, Mr. Editor, as to the purity of the cod liver oil furnished. There certainly was a marked differ- ence in the color produced by the action of nitric acid upon the cod oil and upon a mixture of this with any of the oils used. The light orange or salmon* color, spoken of by some as a resulting color, did not make its appearance. I have not tested any other oil than that of Rushton, Clark & Co. The question now arises as to the value of nitric acid as a test : It certainly is, in my opinion, (assuming the oil I used as pure,) a test by which any adulteration with whale or lard oils to any extent may be readily detected ; the difference in the color produced by its action upon the olive and cod oil mixed, and upon the pure cod oil, is not so well marked as to be readily detected by an inexperienced person, without having a sample of the pure oil with which to compare it. It seems to me that, by ascertaining the specific gravity of the pure oil, any admixture of other oils might readily be detected, as its specific weight would vary according to the adulteration ; by the nitric acid test we might detect some, and by the specific gravity test others. — It may be said that the specific gravity of the genuine oil itself varies according to the skill of the manufacturer in purifying it. To this I answer, that unless some standard of purity shall be adopted, it will be impossible to prevent its adulteration. M. P. SCOTT. EDITORIAL AND MISCELLANEOUS. 217 CORRECTION. In my article on the catoptric test, (see March No.,) I observe a strange confusion oc- curring in the report of the case, p. 139. It should read thus: "J. F has been blind in the right eye, &c." After the description of the opacity of the right eye, read : "The two erect images can be seen distinctly following the motions of the candle. The inverted image is entirely obliterated." On page 138, line 14 from bottom, instead of " the two first and second," read " the first and second." I omitted to mention that the enlargement of the pupil by belladonna or stramonium greatly facilitates the observation of the images. Dissolve a little of the extract of one of these substances, say about the size of one-fourth of a split pea in half a teaspoonful of wa- ter— put a few drops in the eye about half an hour or an hour before examination. When the pupil is enlarged, take the patient in a dark room and hold the clear flame of a candle a few inches before the eye. Move the candle from side to side very slowly, and look be- yond the image usually seen depicted on the cornea, and with a little patient watchfulness you will discover the other two images. If you will hold up the fore finger and middle fin- ger of your left hand before your own face, and pass the little finger of your right hand be- tween them with its point downwards; then move the two fingers of your left hand in one direction and the little finger of the other in the opposite direction, you will have a very good representation of the relative sizes, positions and motions of the three images in a healthy eye. The editor of the Stethoscope will please make the above corrections and additions, and oblige Yours very truly, J. BOLTON. 3EJDOTOMAJL 111 MHTCEILILAirHOOTo We had intended in the present Number to follow up the few ob- servations made in our last, on the very important subject of state organization. Since then, however, the subject has been taken up in the Medical Society. All seem to be of one opinion as to the impor- tance of doing something towards advancing the interests of medi- cal men, but the plan which will best carry out the high objects in view has not been yet sufficiently matured for any action to be taken on it. The whole subject is in the hands of a committee, at the head of which is an able and energetic gentleman, and we forbear to enter into the subject until it reports. We have no doubt but that the com- mittee will digest and report a scheme which will prove satisfactory to all who take any interest in their profession, and which will be successfully carried out by the physicians in the state. We know enough already of their abilities and their feeling of state pride, to be well convinced that they have every requisite to place medicine in Virginia in as proud a position as the Virginia bar has so long enjoyed. We call the attention of medical students to the advertisement of the summer course of lectures at the Medical college in this city. We are not sure but that it is the most instructive course which, students attend, for there is ample time to read on and study the subject mat- 218 EDITORIAL AND MISCELLANEOUS. ter of each lecture before another comes on. The smaller size of the class renders quizzing and conversational instruction more fre- quent and useful, as well as the bed-side of the patient less crowded — and lastly, those allurements to society and the gaiety incident to the winter season in our city do not exist, and the student is more in- clined to prepare himself for the winter course and an easy gradua- tion. Exchanges. Our table is covered with the Medical Periodicals of the month. In addition to those already announced, we have received the follow- ing, in exchange : The British and Foreign Medico- Chirurgical Review. This sterling quarterly is re-published by Messrs. Wood, 261 Pearl street, New York, at $ 3 per annum. The Dublin Medical Press, up to March 6th. This is an excellent weekly, and may be styled the Irish Lancet. It notices us and copies an article. The New Hampshire Medical Journal, Concord, N. H., edited by Dr. Ed. H. Parker. The February No. gives Dr. Mattson a rub for his " arrant quackery," in circulating among the professional, secular and religious public, his pamphlet on "The Curability of Consumption." Dr. M. has been handled rather roughly by several others. The St. Louis Medical and Surgical Journal, a capital bi-monthly, edited by an able corps of gentlemen, viz : Drs. Linton, Moore, McPheeters and Johnson. The Number for January and February, opens with a strong review of the opinions of the London doctors, who have been preaching a crusade against the speculum vaginae, from the pen of Prof. Pallen, formerly of this city, but now profes- sor of obstetrics in the St. Louis University. The Ohio Medical and Surgical Journal for March has been received. Its spirited editor, Dr. R. L. Howard, announces his intention of leaving the United States immediately, on a visit to the schools and hospitals of the old world. We envy his happy lot, and hope that he will enjoy a prosperous voyage. We can but feel elated and nattered by the high stand and charac- ter given by the medical press of the Union to our work. The large amount of matter which it contains, and the low price at which it is EDITORIAL AND MISCELLANEOUS. 219 published, have been remarked by all our confreres; and the highest compliment that could be paid to the contributors of the Stethoscope, is the fact of so many of their articles having been copied. For the very general and undeserved compliments from the secular press, we are much obliged. The subscription list is rapidly increasing, and the circulation is extending well in other states. Some allowances must be made for our faults, as the enterprise is yet in its infancy, and the editorial department cannot command the entire attention of the editor. Close of the Session of the Richmond Medical College. The ceremonies of commencement of the medical department of Hampden Sidney college took place on Friday, 14th inst., in the pre- sence of a numerous and brilliant assembly. After the opening prayer by the Rev. Mr. Woodbridge, Prof. Maupin announced the following gentlemen as having passed an examination, rendering them worthy of the doctorate, and the degrees were conferred by the Rev. W. Green, president of the college : Homer L. Anthony, George M. Bowen, Wm. Burke, Patrick H. Cabell, Daniel S. Evans, Samuel C. Gholson, Meriwether Lewis, John G. Lumpkin, John K. Marable, Wm. McGwigan, David McQueen, Thomas B. Miller, Samuel Nicholson, Robert F. Page, Albert C. Pleasants, Wm. A. L. Potts, P. K. Reamey, Quintus A. Snead, Wm. O. Snelling, John D. Stuart, Pittsylvania, Culpeper, Richmond, Richmond, Campbell, Richmond, Essex, Hanover, Halifax, Isle of Wight, Richmond, Summerville, Tenn. Sussex, King & Queen, Richmond, Pennsylvania, Henry, Goochland, Chesterfield, Patrick, Adol's B. Sutherland, Richmond, Robert P. Toney, Franklin, N. C, Alfred B. Tucker, Jos. C. Vaiden, John B. Walthall, Winchester, James City, Southampton, Thos. J. Wooldridge, Chesterfield, Honorary Degree — Edward D. Kernan, Puerperal Fever, Inflammation. Diseases of the Chest. Fracture. Variola. Puerperal Fever. Fever. Hernia. Electricity. The Pulse. Neuralgia. Hysteria. Hernia. Rheumatism. The Heart. Bronchitis. Dislocations. Intermittent Fever. Remittent Fever. Haemorrhage. Adult Circulation. Pleuritis. Hernia. Pleuritis. Pneumonia. Pneumonia. Russell county, Virginia. 220 EDITORIAL AND MISCELLANEOUS. It was then stated that the number of candidates for the gold me- dal was five — each one handing in an essay of considerable merit. Two of these, one signed Faustus and the other Stethoscope, evinced such equal claims for reward, that it was found difficult to judge be- tween them. The decision, however, was in favor of Faustus, whose real name proved to be Thomas B. Miller of Summerville, Tenn. Dr. Green presented the medal, and addressed the successful candidate in appropriate and moving terms. The proceedings were closed by a beautiful valedictory on the part of the faculty, delivered by Dr. C. P. Johnson. At night the graduates, together with the faculty and many profes- sional gentlemen, partook of a sumptuous entertainment at the hospi- table mansion of Professor Maupin. SOCIETY OF ALUMNI. The annual meeting of the Society of alumni of the medical de- partment of Hampden Sydney college, was held in the chemical hall of the college, on Thursday evening, March 13th. The president, Dr. C. P. Johnson, in the chair. The graduates of the present year were then severally elected members of the society. After which Dr. A. E. Peticolas delivered the regular annual address, which was chaste, well written, and did high credit to the orator. A vote of thanks was returned to Dr. Peti- colas. The society then adjourned over to the afternoon of the ensuing day, when most instructive and creditable essays were read by Drs. J. W. Walke of Chesterfield, and George B. Dillard of Spotsylvania, to whom the society tendered a unanimous vote of thanks. The election of officers resulted as follows : Dr. P. C. Gooch of Richmond, President — Dr. J. W. Walke of Chesterfield, 1st Vice- President — Dr. E. Powell of Goochland, 2d Vice-President — Dr. W. E. Wilson of Richmond, Corresponding Secretary — Dr. A. E. Peti- colas of Richmond, Recording Secretary — Dr. Wm. T. Taylor of Henrico, Treasurer. Dr. Isaac T. Forbes of Fluvanna received the appointment to de- liver the address, and Drs. W. T. Taylor and Carthon Archer of Henrico, to read essays at the next annual meeting. The following gentlemen were chosen by the president to represent the society in the American Medical Association of 1851, which as- sembles in Charleston, S. C, on the first Tuesday in May : Dr. C. P. Johnson, Dr. A. E. Peticolas, Dr. J. W. Walke, Dr. W. T. Tavlor, Dr. L. B. Anderson, Dr. J. T. Forbes, Dr. S. C. Gholson, Dr. J. G. Lumpkin, Dr. Wm. Burke. To these was added, by a vote of the society, the president, Dr. P. Claiborne Gooch. On motion, Resolved, That hereafter all persons admitted as mem- bers of this society shall be required to pay an initiation fee of one dollar. A. E. PETICOLAS, Secretary. EDITORIAL AND MISCELLANEOUS. 221 Medical Society of Virginia. The meeting on March 18th was very well attended by members and visiters. A number of gentlemen were elected to membership and some twenty nominations made. The report on anaesthesia was then read and made the subject of discussion for the next meeting, April 15th. Several resolutions were adopted, among which are the following : " That the delegation to the American Medical Association be in- structed to tender an invitation to that body, in the name of the Medi- cal Society of Virginia, to hold its next annual meeting in Richmond. ".That the president be invited to deliver an address to the society at its annual meeting in May next. " That a committee of three be appointed to enquire into and re- port on the expediency of building a hall for the use of the society." The new form of the diploma was read and approved, and the committee discharged. After the transaction of some other business of local importance, the president announced the names of the delegates to the American Medical Association, and the secretary was directed to prepare their credentials and forward them to Charleston, where delegates will find them on their arrival. The following list of delegates to the American Medical Association has been furnished us. It is expected that all will attend, but an al- ternate who is present will take the seat of any absent delegate : From the Medical Society of Virginia, Dr. Landon Rives, Dr. Rob't W. Haxall, (president,)* Wm. A. Patteson, Beverley R. Welford, G. Lane Corbin, P. CI. Gooch, M. P. Scott, Walter F. Jones, Jno. Prosser Tabb, H. C. Worsham, James Beale, George F. Terrill. ALTERNATES. Dr. J. Spottswood Welford, C. S. Mills, Jno. N. Broocks, F. W. Roddy, Wm. D. Meriwether, W. W. Parker, Dr. A. T. B. Merritt, G. G. Minor, Jno. R. Walke, L. B. Anderson, Tho's E. Cox, J. J. Thweatt. * Appointed by the society. 26 222 METTAUER ON THE PROPHYLAXIS OF PUERPERAL FEVER. From the Medical Department of Hampden Sydney College. Professors L. W. Chamberlayne and D. H. Tucker; Alternate, C. P. Johnson. Medical Department of Randolph Macon College. Professor Jno. P. Mettauer. [Other constituent bodies will please forward a list of their delegates for announcement in the May No.] SyWe are requested by the editors of the Charleston Medical Journal and Review, to correct an error which crept into their January Number. It stated that the American Medical Association meets on the second instead of the first Tuesday in May. Notice to Correspondents. Communications have been received from the following gentlemen, but too late for the present Number : Drs. T. J. Garden, L. S. Joynes, T. J. Young, D. T. Martin, R. E. Jennings, Wm. M. Broocks. f^p3 Articles intended for publication must be written on only one side of the paper, and should be received by the 10th of the month to se- cure a place in the next number. The Prophylactic Treatment of Puerperal Fever. By John P. Mettauer, M. D., L. L. D., Professor of the Principles and Practice of Medicine and Surgery in the Medical Department of Randolph Macon College of Virginia. The practical views communicated through this paper, have been entertained by the writer now more than twenty years, and the lapse of time since their adoption, has fully confirmed their utility, if not their correctness. Puerperal fever has ever been a disease profoundly interesting to him, but circumstances early transpired to render it painfully so; and he owns that it was a heavy domestic bereavement, that gave the first impulse to the reflections which lead him to adopt the mode of treating this cruel disease, about to be presented through this paper. In his early intercourse with puerperal fever, he had to deplore occasionally the inefficiency of the established modes of treating it. In some cases, although early and actively treated, after the disease had formed, it pursued its course obstinately to a fatal ter- mination, defying medical interposition, seeming only determined to sever the tenderest ties of the dearest of human associations. It will not be necessary to premise a history of puerperal fever, as introductory to the practical remarks about to be presented. Nor METTAUER ON THE PROPHYLAXIS OF PUERPERAL FEVER. 223 need I state anything farther in relation to the nature of the disease, than that I regard it as inflammatory, although it varies much in the intensity of the phlogosis with which it is attended in different cases. The numerous post mortem examinations in fatal examples of the disease, conclusively establish the inflammatory nature of it, even if the symptoms during life fail to do so. Upon this point a majority of the profession are united in opinion ; and I will add, that the method of treating puerperal fever, about to be described, and pursued by me for more than twenty years, was deduced from my unshaken belief of its inflammatory nature. It would be easy to shew that pregnancy and parturition, are succeeded by conditions of the organs implicated chiefly in those processes, and which are the usual seats of the local affection of the disease, which predispose to inflammation in other or- gans. A state of inaction and debility, with more or less suspension, or perversion of the functional exercises of the organs concerned in pregnancy and parturition, succeeds delivery in every case, in greater or less degrees of intensity. Contusions, overstrains, or over-disten- sion from any cause ; surgical operations, undue irritation, or excita- tion of an organ, or from suspension of vital action for a time, as from the operation of inordinate pressure, or low temperature upon a part, all induce a like condition ; and this state, it is reasonable to suppose, predisposes to the inflammations generally following the ope- ration of such causes ; and it is well attested that they do result, in a very large majority of instances. After pregnancy and parturition, the uterus, and its appendages, the peritoneum, and the abdominal or- gans generally, are left in a state of inaction, debility, and, to a cer- tain extent, are actually collapsed. While in this condition, the func- tional exercises of the implicated organs are more or less disturbed, perverted, or perhaps suspended ; and it is this state, which, if pro- foundly impressed upon the organs, or too long continued, that pre- disposes to puerperal inflammation or fever. Other causes may co- operate, in some cases, with that post-parturient collapse of the organs, such as contagion, or a predisposition to some other disease, espe- cially typhoid, typhus, and eruptive fevers, erysipelas, rheumatism, catarrhal fever, and some others, in the causation of puerperal fever. But the debility and inaction of the organs concerned in pregnancy, and consequent perverted secretion, seem to be the intimate predisposing pathological conditions of the disease ; while the others are to be re- garded, as adventitious or incidental, differing essentially, too, from those occasional causes that often induce the disease, as inciting or producing agents. In some instances, puerperal fever has come on without the known operation of an exciting cause. In those cases it is probable that the predisposing condition was so profoundly im- pressed upon the organs, as to act also as an exciting cause, nay, to constitute the initial stage of the disease. A majority of cases, how- ever, result from exposure to variable temperature, or from catarrhal irritation or colds. Any disturbing cause, capable of inducing fever or diminishing general secretion, may, and often does operate as an exciting cause of the disease when there is pre-existing predisposition to it. It is not unusual for the too early use of solid food of stimula- 224 METTAUER ON THE PROPHYLAXIS OF PUERPERAL FEVER. ting qualities, alcoholic incitants, conversation, or premature undue exercise of the body or mind, to cause puerperal fever; and in such cases, there doubtless must have been pre-existing predisposition to the disease. The region of country from which the facts supporting the views presented through this paper are drawn, has not afforded a solitary case of puerperal fever that could be traced to contagion as its cause ; nor is it believed that such a cause ever does induce the disease in this section of country ; and yet numerous cases have oc- curred, in which the disease was marked by the characteristic symp- toms during life, and the usual anatomical appearances after death. Contagion, nevertheless, may, and doubtless is, to be regarded as a cause of puerperal fever under fit circumstances, such as may arise in cities or other situations favorable to the generation of idio-miasm, and its propagation from individual to individual in the causation of the disease in question. In considering the prophylactic treatment of puerperal fever, it will be proper to examine it under the following heads, that is : I. Purging in a few hours after delivery. — This will be demanded when parturition has been protracted and attended with great suffer- ing, or when the latter period of pregnancy has been distinguished by those symptoms which indicate a morbidly impressible state of the uterus and its appendages, as well as of the contiguous organs that are usually involved in the processes of pregnancy and parturi- tion. In some cases the last month, or the closing period of it, of utero-gestation, is attended with undue restlessness ; uneasiness, or tenderness of the abdominal wall; a feverish disposition, with or without thirst ; a furred tongue ; impaired appetite ; frequently sick stomach and vomiting ; constipation or diarrhoea ; sleeplessness ; oc- casionally delirium ; and some other symptoms, indicating an unu- sual degree of irritation. Occasionally, too, these examples of labor are attended with a preternaturally warm or cool state of the liquor amnii, discoverable as that fluid escapes from the ruptured membranes, and a correspondingly warm or cool condition of the uterine surface. The pains and suffering of parturition in such cases are generally more intense and distressing, and the woman experiences less of the customary sanguineous discharge than in ordinary labors, as well as more exhaustion after delivery has taken place. In a case thus cir- cumstanced, it would be necessary to purge in three or four hours after delivery, nay, sometimes sooner, especially if there is more ab- dominal tumidness than usual; and the cathartic I have most fre- quently employed, is that supplied by the annexed formula : fy. Aloes Socot., - - - gr. vii. Scam. Alep., - - - gr. v. Calomel, __■_'"_ gr. viii. Ipecacuanha, - - - gr. i. Water S. Q. Make the mass into four or five pills for a dose. This compound may be administered in the form of pill or powder. The earlier purging is effected in these examples the better. In METTAUER ON THE PROPHYLAXIS OF PUERPERAL FEVER. 225 some instances I have exhibited the cathartic before the delivery of the secundines, when symptoms of threatening character existed ; and, in all such cases, the action of the cathartic should be quickened by the employment of purgative injections, repeated after intervals of an hour, until the bowels are impressively purged, commencing with the enema in two hours after the administration of the purgative dose, and to enjoin it upon the woman to lie chiefly on the right side, until the medicine passes from the stomach. The cathartic above advised, has uniformly met the indications in the cases in which I have em- ployed it ; and has, as constantly, operated without distress of any kind to the patient, while its action has been impressive and secer- nent. It seldom fails to procure copious, consistent, and feculent dis- charges from the bowels ; and rarely ever operates too freely. Other cathartic substances, of like qualities, might be employed in these cases, and with equal benefit ; but, the compound here presented, having so constantly met the indications, I have not been willing to modify, or substitute it, by the employment of other means in the ex- amples now under consideration. If the first dose fails to procure full and feculent discharges, the remedy must be repeated in eight or ten hours. In these cases, the treatment should be continued until every threatening symptom disappears ; and, in a majority of in- stances, a single dose or two will accomplish it. The bowels must be kept soluble during convalescence, by the use of any mild aperi- ent. Magnesia taken at bed-time, in teaspoonful doses, has often maintained the bowels easy. In some cases, I have employed a pill composed of aloes, jalap, and colocynth in powder, just in doses to act moderately, and with the best results. As an auxiliary means of treating these examples, it will be useful, if the skin is dry, to use grain doses of ipecacuanha, once or twice of a night made into pill, until that state is corrected. It will also be safe to employ some diuretic, and the infusion of " pine-tops," I have uniformly preferred, if the stomach did not loathe or reject it. Taken cool, the tea is not unpleasant ; nay, with many it is grateful, being acid, and not very strongly terebinthinate in taste, and it is decidedly diuretic in its action with the economy. Restrictions on diet will of course be necessary, as well as on the deportment of the woman generally, while a morbid impressibility, or liability of the system to inflammation exists. In a vast number of cases, marked too, in many instances, by symptoms of the most menacing character, the simple treatment here briefly pointed out, has been employed by me with unvarying success. In not a solitary instance, in which I adopted it, has puerperal fever resulted ; and there is not a doubt that most, if not all of the cases, would have eventuated in that ter- rible disease had it not been employed. If it would render this paper more useful to my brethren, I could append numerous cases to it, with the details of their treatment ; but such an appendage would only lengthen, without adding to its value. In confirmation of the value of the treatment here advocated, as far as a solitary case can do so, as well as of the efficiency of the purgative, I will state that a highly intelligent physician of a flourishing town of Virginia, employed 226 METTATJER ON THE PROPHYLAXIS OF PUERPERAL FEVER. it in an extremely threatening case, some years since, at my sugges- tion— being at the time myself on a visit to him, and with complete success. The lady, who was intelligent, and of a highly cultivated mind, as well as her intelligent husband, who was a well-educated physician, as also the attending physician already referred to, were equally struck with the effects of the cathartic, both as to its curative efficiency, and pleasant and painless operation upon the bowels. II. Purging more remotely after delivery. — When the signs indica- tive of predisposition to puerperal fever are less urgent or threatening, and when the labor has not been distinguished by grave abnormal concomitants, purging may be deferred some ten or twelve hours after delivery, or until the succeeding morning ; and then the cathartic already suggested will be found to meet the indications as perfectly as in the preceding description of cases. Occasionally I have em- ployed a cathartic pill, composed of aloes, jalap, and colocynth in powder, according to the annexed formula, and with the best results : ft. Aloes Socot., " ~\ Jalap, Rad. Pulv. a. a., ) ° * Colocynth, Pulv., gr. in. Water S. Q. Make into three or four pills. From one to three to be taken at a time. This compound, however, is better suited as an aperient, unless taken in doses of three or four pills, which then might nauseate, or produce higher cathartic effects; it is very well adapted to the sequel of the examples we are considering, after sufficient purgation with the first described pill, merely to maintain the bowels soluble, or to excite them in some moderate degree, from time to time. When labor has been somewhat protracted, and more painful than usual; and, espe- cially, if considerable haemorrhage has followed the expulsion of the secundines, it would not be safe to depend on this pill. In such cases, the first described pill should be preferred, and its action must be hastened by the use of enemata, as was advised in the first descrip- tion of cases, and by position of the body on the right side for an hour or two after the medicine is taken. The presence of undue abdomi- nal tenderness, will also indicate the necessity of employing the first described pills ; and the remedy must be repeated daily until the case ameliorates. The bowels should be maintained soluble; and if the pills of this second formula are too irritating to the stomach or bowels, as will sometimes be the case, the annexed formula may be employed: ft. Aloes Socot., - - - - gr. ii. Jalap, Pulvo., - - - - gr. hi. Rhei. Pulv., - - - - gr. iv. Ipecacuanha, - - - - gr. i. Water S. Q. Make two or three for one dose. These pills operate mildly, and produce both aperient and diapho- retic effects. These should be taken at ordinary bed-time, and if not METTAUER ON THE PROPHYLAXIS OF PUERPERAL FEVER. 227 active enough, an enema may be employed the succeeding morning. As was advised under the first head, should the skin be dry, it will be necessary to employ grain doses of ipecacuanha nightly, and com- bined with the bi-carbonate of potash and rhubarb, according to the annexed formula : ft. Ipecacuanha, - - - - gr. v. Bi-carb. Potass., - gr. x. Rhub. Pulv., - - - - gr. xii. Water S. Q. Make five pills — one the dose. One of these pills may be taken at 9 o'clock, and again at 12 during the night; if it is deemed very important to act upon the skin gene- rally, a single pill, at ordinary bed-time, and at 10 in the forenoon, will meet the indications. When the lochial discharge is defective, or suspended, besides ca- thartics, it will be necessary to have recourse to a terebinthinate lini- ment, over the hypogastrium and loins, formed according to the an- nexed formula : ft. Spirit Terebinth. Ten., - - 3 j. Adep. Suil., - - - - 1 vj. Mix and keep in a wide mouth jar. This liniment may be freely applied twice daily, until the lochial discharge re-appears, both with the cases under this head, as well as the first. Usually, purgation restores general secretion promptly, and the lochial discharge now re-appears after that change takes place, without resorting to the turpentine. Care should be taken not to put the child to the breast for some hours after the application of the tur- pentine, or it may be rendered sick by the action of the terebinthinate upon its economy, through the milk of the mother — convulsions may even follow. The diet should always be restricted, and every thing carefully guarded against that tends to induce fever or inflammation after delivery. III. Purging in all cases after delivery. — This has been my custom for many years, believing that women are more or less predisposed to puerperal peritonitis and fever, in every case after parturition. In twelve hours after delivery, I invariably order a cathartic, mild or otherwise, no matter how favorably situated the case may be ; and I believe that many cases, nay, I might with propriety say all, have been benefitted by the practice more or less. I think it very probable that attacks of puerperal fever have been warded ofF by it, when a predisposition to the disease was not suspected. Certainly the prac- tice greatly ameliorates the condition of the breasts during the setting in, and early periods of lactation. It also guards patients against cer- tain cutaneous and other irritations, frequently consequent upon par- turition. I have little doubt that it has prevented phlegmatia dolens in many instances ; and I am led to this conclusion, from the fact, that no cases of this painful disease have occurred in my practice since it was adopted. Patients, however, are often unwilling to sub- 228 SELECTIONS. mit to it after delivery, when, as they express it, they " feel so well." And, in some cases, females entertain such a horror for medicine, that they will incur the danger of an attack of puerperal fever, rather than consent to take a cathartic, when they do not feel really sick. It must not be supposed from the preceding remarks, that I have not met with cases of puerperal fever since the prophylactic treat- ment I have advocated in this paper was adopted by me. On the contrary, I have treated many cases in the various stages of the dis- ease ; and I would state, country practitioners are peculiarly liable to meet with it somewhat advanced, by reason of the uncertainty of the true nature of the symptoms which mark the early periods of its pro- gress, and the consequent delay in calling in medical aid. But I have never met with an instance of it following labors managed by myself, since the adoption of the prophylactic treatment I am advocating, with females who submitted to such treatment. Puerperal fever is a formidable disease, has brought grief and sorrow into many a happy family, by reason of its intractable nature and rapid tendency to end fatally ; and any innovation upon the plans of treating it, now gene- rally adopted by the profession, would be justifiable ; and should the plan I have proposed possess no other merit, it will at least shew that I have not regarded this cruel disease with indifference, and that I have made an effort, though feeble, to disarm it of its difficulties as well as its dangers. In conclusion, I would earnestly call upon my brethren as medical men, and as the friends of suffering females in the trying hour of childbirth, to give the prophylactic treament of puerperal fever, briefly described in this paper, a trial ; and if it shall prove as success- ful in their hands as it has uniformly done in my own, I shall feel more than repaid for the time and trouble it has cost me in the preparation of this paper. — Charleston Med. and Surg. Journal. Tumor of the Neck of extraordinary size, successfully removed. BY P. C. SPENCER, M. D., OF PETERSBURG, VA. Thomas Wilkinson, a native of the neighboring county of Sussex, 37 years of age, placed himself under my care for the surgical treatment of an enormous tumor of the neck. The history of the case, collected from accounts given by himself and friends, was as follows : The tumor had been in existence thirty years. It was described as being located, when first observed, at the angle of the lower jaw, and beneath the lobe of the left ear. Its presence and growth being wholly unattended by pain or annoyance of any kind, it does not seem to have created anxiety or to have attracted much notice during the period of his youth. This apathy, however, was not of long du- ration. Before he reached his twentieth year, its great size, and the deformity and annoyance it occasioned, led him earnestly to desire relief. It was then sixteen or eighteen years before the time of his applica- tion to me that he, for the first time, sought surgical advice and assist- SELECTIONS. 229 ance. The tumor was at that time represented as being double the size of a large orange, and firmly embedded beneath the angle of the lower jaw. He was immediately placed under treatment necessary to prepare him for its excision by a distinguished and very bold surgeon of this place, since deceased. When the day fixed for it arrived, however, he was, much to his disappointment and chagrin, dismissed without the operation, the sur- geon urging as a reason for the postponement, that he had not been able to prepare himself with some necessary preliminary. Wilkinson was desired to return home, with the assurance, that so soon as this could be accomplished, he should be sent for. This promise was ne- ver fulfilled. Whatever may have led to the postponement on the part of the surgeon, the impression was created on the mind of the patient and his friends, that the operation required was deemed one of a nature too hazardous to be attempted with any prospect of success. This impression was subsequently confirmed as the case wore on, since the many medical men, who, from time to time, obtained a sight of the disease, as the man's business called him from place to place, were almost unanimously of opinion, that the safe removal of the tu- mor was beyond the reach of art. With this conviction, the man pa- tiently resigned himself to his fate, awaiting the issue. But the disease did not remain idle. Mass after mass of degene- rate structure continued to shoot out from every side ; reaching down- wards it touched the shoulder, the whole breadth of which it proceeded to occupy, and then on both breast and back, it ultimately fell in large folds. Finally, its great weight, acting upon a frame already worn down and emaciated by the ceaseless irritation of its presence, pre- cluded all employment, allowing him to remain in an erect posture for a short period only, and that at long intervals. In addition to all this, decay ultimately set up in the morbid mass. Patches of ulcera- tion appeared on its periphery, resulting apparently from imperfect nutrition, caused either by pressure or lesion upon its nutritive vessels. Abscesses formed in its interior, tunnelling it with large sinuses, which constantly discharged offensive matter, and hectic fever supervened. Feeling that he could live but a short time as he was, and being convinced that the excision of the tumor afforded him the only chance for his life, the patient had arrived in town with the determination to have the operation attempted. After a minute and tedious examination of his case, with several professional friends to assist me, we found it almost impossible to come at anything like a positive opinion as it regarded the safety or practicability of an operation. This ambiguity and embarrassment arose from the exceeding difficulty of ascertaining correctly the parts involved in the attachment of the tumor, and in defining the nature of the operation required for its removal. Firmly attached by a strong and almost unyielding band to the whole side of the neck, its sides shelving over all around, below, be- hind, and before, anything like a satisfactory examination was wholly precluded, since there was but a narrow space for the hand to pass 27 230 SELECTIONS. under to effect the exploration. Nor was this all : admitting that a free examination of the attachments of the tumor could have been made, its immobility on its stem, and the extent of these attachments were so great that nothing positive could have been ascertained of the parts involved likely to be wounded in an operation. Nothing is easier than to prove this by a glance at the bounds of its attaching surface. Extending from an inch above and behind the lobe of the left ear, these ran posteriorly on a line with the sterno-cleido mastoid muscle, (which it covered with the great vessels of the neck,) down to within an inch of the clavicle. In front, its connection ran from the ear over the cheek to a point midway below the chin, where it passed again downward in a line with the trachea to the top of the sternum. The whole formed a triangular connection or band, firm and almost immovable, at least six inches through its longest line. It was a prominent question in the enquiry, as to whether there would be danger or probability of wounding either one of the great vessels of the neck. This result, under ordinary circumstances, would not have been feared by the surgeon ; but, in the present case, the acci- dent could but be fatal, for the very plain reason, that the courses of these vessels in their entire extent were so completely covered by the diseased mass, which was so unyielding and immovable as to pre- clude entirely the possibility of securing them by ligature or other means, did it occur. After being made fully sensible of these difficulties, the patient still persisted in his determination, and the operation was therefore under- taken as a dernier ressort. It was necessary to place him on a more generous diet than he had lately allowed himself, in order to ensure him sufficient strength for trial. Some eight or ten days sufficed for this result, and on the 9th of January, 1844, the operation was performed. A narrow table was provided, in a room tolerably well lighted, on which the patient was placed, lying on his right side, with his head elevated. Whilst in this position, in the presence, and with the assistance of Drs. Pee- bles, Jones and W. Michie, all of Petersburg, I proceeded to ope- rate. My first design was to raise the tumor from behind, by cutting it away from the whole line of its posterior attachments, freeing it there- by from the great vessels of the neck as early as possible. For this purpose an incision was commenced about two inches below the ear, and carried on and down to the tumor, to within half an inch of the clavicle. The skin was carefully, but with great difficulty, (so closely was it agglutinated to the diseased mass,) dissected off to the neck. When this was completed, I cautiously proceeded to divide the ad- hering bands which had been exposed by the incision. The sterno- cleido mastoid muscle, attenuated to a mere filament, had been partly brought into view, and being closely affiliated to the diseased mass, was divided across, above the point where it is decussated by the omo-hyoideus. When, by these means, its lower part had been freed, so that the tumor could be raised, the carotid artery was plainly seen beating in SELECTIONS. 231 front of the line of the original incision, but now about an inch back- wards from its still adhering surface. The tumor was next held, raised, and borne slightly forward, when the dissection was carried on without danger of wounding the vessels. The very strong and firmly adhering bands which connected the ex- crescence with the mastoid process of the temporal bone, with the tuberosity of the occiput, and with the transverse processes of the upper cervical vertebrae, were next severed in the order in which they presented themselves. Up to this time no vessel of any importance had been wounded ; the haemorrhage had been slight, the only embarrassment to the opera- tion arising from the unpleasant strangulation resulting from the pres- sure of the tumor on the trachea, as the patient lay, through the una- voidable manipulations on it, already described. Starting under the ear, at the origin of the first, another incision was next extended through the skin down to the tumor, across the cheek to the chin, and then carried downwards on a line with the trachea, finally terminating in the first j ust above the clavicle. Much time was next required in removing the adhering skin from the surface of the tumor, which was carefully done through the whole line of the incision, that it might serve as a covering to the wound, and many considerable vessels were wounded, two of which, one of them near the angle of the inferior mixiliary bone, the other beneath the symphysis, requiring the prompt application of the ligature. When this tedious and exceedingly painful dissection was completed, the exhaustion of the patient was so great that I was forced to sus- pend my dissection about the throat, in order that he might be allowed to breathe with the necessary freedom. But all its adhering bands had been severed, and the tumor could be raised ; and, so soon as the patient recovered from this partial syncope, its final excision was readily completed. Though overcome and greatly exhausted, the patient was found to be in quite a favorable condition ; his pulse was good, and he had not suffered so much from haemorrhage as had been expected, the principal loss being, in fact, venous blood. A reasonable time having elapsed, and there being still little or no decrease of this oozing from the di- vided veins, a weak solution of creosote was applied to the wound. It had the desired effect almost immediately, and I proceeded to the dressing. The flaps of the skin, which had been left, covered the wound very well, considering that the nature of the case, leaving no choice in the matter, had obliged us to dissect without regard to this object, and having carefully brought them together, they were secured, and the wound closed by straps of adhesive plaster. The dressings were completed, and the patient placed in bed in forty minutes from the time the operation commenced. No accident occurred, and the night succeeding the operation was spent quietly and comfortably. On the second day there was a slight rise of fever, which was at once successfully combated by a mild purgative. It is considered entirely unnecessary to detail further the progress of the case, for after this time no constitutional symptom arose, and its management became entirely a local affair. 232 SELECTIONS. The improvement of the general health proceeded pari passu with the healing of the wound, which, under the simplest treatment, was gradual yet progressive. On the 23d of January he left his bed en- tirely, and, late in February, he returned home in good health, and so altered in appearance that his nearest neighbors did not at once recog- nize him. He has been seen within a few weeks by the writer, and he re- ported that the improvement of his general health had steadily pro- gressed since his return home. The tumor weighed within a fraction of twelve pounds. It evidently belonged to the class of non-malignant tumors. A further estimate of its true nature cannot be made, since, preferring to preserve it as a specimen, no dissection was made into its structure. — American Journal of Med. Science for 1845. [We copy the above case because it was an operation of very great importance, and done without " going to Philadelphia." It has been insinuated that Dr. Spencer has concealed the fact of the ultimate fatal result of this operation. It is not so, for the subject of it may be seen in the Petersburg market-place weekly. — Ed.] The Claim of Physicians to compensation for services ren- dered in Medico-Legal Examinations. It seems scarcely credible, that in the state of South Carolina, which is noted for the liberality of her acts and for her enlightened policy, the physician is expected, nay, required, to make post mortem examina- tions when summoned by the coroner, without receiving the slightest compensation for his services. This is so flagrant an act of injustice, so grievous a wrong, done the profession, as to demand their serious consideration, and incite them to strenuous exertions to effect a recog- nition of their rights. When it is remembered that the medical man expends hundreds, perhaps thousands of dollars, that he toils year af- ter year, for the acquisition of the most complex, and, consequently, the most difficult of sciences, it is reasonable that his knowledge should re- receive its reward, when practically applied for the public as well as the private weal. When invited by the coroner to make the examina- tion of a body, in case of suspected poisoning, murder, etc., he has al- ways willingly rendered his services to the state regardless of the in- convenience to which he may be exposed. Is it not just that he should receive a quid pro quo? The lawyer who conducts the case on the part of the state receives a compensation, and why should not the physician, who is perhaps mainly instrumental in establishing the guilt or innocence of the accused ? It would be superfluous for us to do more than merely advert to the cases on record, in which medical tes- timony has been all-important to the conviction of the individual sus- pected of having perpetrated the crime. We need only instance the dreadful tragedy, recently enacted by one of our own profession, to convince any one of the great weight attached to the testimony of the scientific physician. SELECTIONS. 233 We are not sufficiently acquainted with the laws of the several states of our confederacy, to know whether physicians in the majority of cases are paid for these examinations or not. It is only lately that Georgia has rendered this act of justice to her physicians. By a law passed at the last session of the legislature of that state, as we learn from the July Number of the Southern Medical and Surgical Journal, the physician is allowed, for each post mortem examination, when death has resulted from external violence, where no dissection is re- quired, the sum of ten dollars ; for the same, where dissection is ne- cessary, and where no interment of the body has been made, twenty dollars ; for the same, after one or more days' interment, thirty dollars; for the same, when any chemical analysis is required, the sum of fifty dollars, and the expense of such analysis. In reference to this matter, the above journal remarks : " We are pleased that this tardy act of justice to the medical pro- fession has been done ; but, at the same time, we are constrained to say that the compensation for post mortem examinations, where chemi- cal analysis is required, is entirely inadequate. In almost every case of this kind, the entire responsibility is thrown upon the physician. Upon the correctness of his analysis, the reputation and life of the ac- cused depend. His opinion alone determines the question whether or not a crime has been committed. To place a man under such a weight of responsibility, and then to offer to compensate him for fifty dollars, shews a very low appreciation of the profession, or a very ex- travagant estimate of the value of money." Now, although we cannot comprehend how a physician's responsi- bility is lessened, or his conscience relieved of remorse, by pecuniary reward in the event of the execution of an innocent person convicted upon his testimony, as the result of his examination, still we coincide with the editor that the fee allowed should be proportionate to the amount of labor and of knowledge required of him ; that fifty dollars, for instance, for a chemical analysis, is wholly disproportionate to the expensive process that it involves. The statute of the state of New York, we are told by the Northern Lancet, directs the coroner to summon a physician to attend profes- sionally at an inquest, but does not provide for his remuneration. A numerously signed petition to that effect was presented to the legisla- ture, during the session of 1842— '3, but its remonstrances were utterly disregarded. Inasmuch, therefore, as the state has not complied with the demands of the profession, the physicians when summoned by the coroner, although obliged to attend, do not generally touch the body, as he cannot force them to do it. In Great Britain the fees are awarded to the physician in a scale according to the services performed. In France likewise, and, we presume, upon the continent generally, physicians are remunerated. And shall this state be one of the last to comply with the just de- mands of the profession ? It has happened that, time after time, bills for post mortem examinations, made at the instance of coroners, have been presented to our legislature, and have, so far as we knowT, inva- riably been rejected. Why is this ? What incentive is held out to 234 SELECTIONS. the physician to qualify himself for such arduous and responsible du- ties ? Were it not that he was actuated by a conscientious discharge of his duties as a citizen, and that he dreaded the loss of reputation, he might often be utterly indifferent to the examination made, and to the evidence subsequently delivered by him. But we contend that the physician should not only be liberally re- munerated for his examination, but that he should be adequately com- pensated for the evidence subsequently delivered in court. With the physician, as with other business men, time is money, and as he is re- quired to spend hours, perhaps, as is not unfrequently the case in ci- ties, days in attendance on the court, waiting his turn to be interro- gated, it is but right that he should be fully paid. Add to this, the annoyance to which he is occasionally subjected by unscrupulous lawyers, and he certainly has sufficient cause for complaint. In or- der to shew to what great inconvenience physicians are subjected by being required in these cases to attend court, we have the statement of Dr. James Webster, professor of anatomy in Geneva college, New York, in his introductory address to the class of 1849-'50, to the ef- fect that on one occasion, physicians were summoned from New York city, Albany, Utica, Auburn, Geneva, and himself from Rochester, to give evidence in a case that was to be tried in Cayuga county. He was not onl}r subjected to great loss of time, but also to the expendi- ture of nearly one hundred dollars for examinations, travelling ex- penses, etc., not a dollar of which was refunded him. This is one instance, among many, which he adduces to shew the injustice in the legislature in not awarding to physicians remuneration for the services rendered the state. There is one consideration above all others that should prompt the state to recognize the just demands of the profession in this respect, and that is, their voluntary and gratuitous assumption of the guardian- ship of the public health. When consulted on questions of public hy- giene, the physician, actuated by the noblest impulses of the human heart, viz : a desire to ameliorate the condition of his species — readily and cheerfully imparts all the information he possesses that may tend to the accomplishment of that object. Nay, he is most frequently foremost in devising means for the improvement of the body politic ; whereas, were he to obey the dictates of interest, he would rather en- deavor to promote disease than prevent it. We shall not, for the present, pursue this subject further, our object being merely to direct thereto the attention of our readers, and through them, that of the members of the legislature. It is our intention to move at the next meeting of the South Caro- lina medical association, for the appointment of a standing committee, to be called the committee on the interest of the profession, whose duty it shall be to take cognizance of all matters relating to the good of the profession. — Charleston Medical Journal. The population of Virginia, according to the recent census, numbers 1,428,000, of which 1755 are physicians — giving a ratio of one phy- sician to every 813 inhabitants. SELECTIONS. 235 Quackery Amongst Regular and Irregular Practitioners. The columns of the Lancet have for some time furnished valuable information respecting the adulterations of food and drink ; we rejoice to find that the adulteration of our profession by the intrusion of quacks amongst us is destined to similar treatment, as appears from the fol- lowing : Dr. Johnson instituted a striking comparison between the social po- sition of the lawyer and the physician. Few, he says, know the de- fects of the physician they employ, and no man is acquainted with the excellence of him he refuses to consult. But the lawyer is obliged to produce himself in public, and give evident proofs of his claim to the reputation he enjoys. Like many other sayings of the great moralist, there is more speciousness than fact in these distinctions. The annals of the bar contain as many and as conspicuous examples of shallow, undeserved success, and of neglected worth, as the history of any other occupation, while we feel confident that the medical profession generally, through all its branches, assumes, and maintains as high a standard of intellectual capacity, profound learning, and high moral worth, as either of the two other learned faculties. Some of the great medical celebrities of London do, however, rest on very shadowy foundations. We have always, as our readers well know, constantly wielded the power of this journal to baffle and destroy the advertising quacks, whose avowed occupation it is to deceive and swindle, but we are bound to say the race of semi-quacks within the pale of the profession are hardly less noxious or more derogatory. It is our duty, occasional^, to devote our attention to the latter, for the sake of those whose integrity forbids them to follow any but the straight and labo- rious way, and who are too often left behind in the race by more un- scrupulous competitors. These regular irregulars consist mostly of two classes ; of men who, starting with honorable ambition, and try- ing the pains-taking road without a speedy success, sink into money- making business, and so make their profession a trade ; and of others who had neither a tincture of shame, a sense of dignity, or a regard for truth from the beginning. Of the first class we would speak with tenderness, when they keep themselves in the shade, and content themselves with the great object of their pursuit — wealth. The other class it becomes the correctional police of the press to deal with se- verely, and we propose to pass some of the parties who belong to it under the lash of criticism. It is they who are ever ready to seize every novelty, every real or fancied improvement in practice, and push it to the verge of quackery, so that the public cannot really see where the profession ends and where quackery begins. Such men are more dangerous and more mischievous to the profession than the avowed irregulars. We shall take an early opportunity of applying these general remarks to particular instances, though every medical man must, in his own sphere, be able to make an abundance of such ap- plications.— Lancet. We are glad to find that this praiseworthy effort to arrest the pro- 236 SELECTIONS. gress of quackery amongst regular practitioners is to be directed against notorious offenders principally. It is no easy matter to define where quackery begins in the medical ranks, and therefore no easy matter to restrict the application of the term to its proper objects ; but there is no difficulty in dealing with him " who has had neither a tinc- ture of shame, a sense of dignity, nor a regard for truth from the be- ginning." The barefaced, impudent, professed charlatan, who openly avows his contempt for all restraints which interfere with his proceed- ings, can be easily culled from the flock, for the brand which distin- guishes him has been applied with his own hand. The base arts of fawning, fulsome adulation, which, without a blush, he employs to in- gratiate himself with every class of society, from scum to dregs, serve as so much pitch and tar to warn all honest men to avoid coming in contact with him ; while the practices necessary for the successful conduct of his trade approach so nearly to tangible criminality that cautious men stand aloof. Nothing, however, of this kind takes place until the finger of scorn is pointed. As long as he suits the taste of " the public," makes himself useful to confederates, and does the work of his employers without scruple, so long does he retain his po- sition ; but the moment his true character comes to be exposed, then does he find his level, and hence the value of the interference here proposed to be undertaken. That it is the duty of a journalist to hold up to public scorn the evil-doers of our profession, there can be no doubt. He is the guardian, and the only guardian of our body against the contamination which such entail. He it is who must remind us of the truth of the homely saying, that "one scabby sheep corrupts the whole flock," for without his admonition it will be forgotten. Neither " the public" nor " the profession" care to be very inquisitive as to the moral qualities of the man who answers a purpose ; they are not fastidious ; and with them men seldom lose caste because they act without scruple, provided they succeed. People should, however, be taught, and especially people of our profession, that such laxity is not a universal failing amongst us ; they should know that, some at least, shun a black sheep, however many may bear him company, be- cause of his value as a companion, or as a necessary aid in the pur- suit of their objects. — Dublin Medical Press. A New Remedy for Short-Sightedness. BY A. TURNBULL, M. D. Addressing the editor of The Lancet, Dr. Turnbull says — I beg to call your attention to a newly-discovered remedy in cases of short- sightedness, which I have applied with very considerable success. A few months ago, I observed that persons who are short-sighted, when looking at objects at a distance, partially close their eyelids, for the purpose of overcoming the difficulty they find in discerning them. This action is instinctive; it is a natural effort to adjust the eye to an increased sphere of vision. It is well known that short-sightedness SELECTIONS. 237 depends not only on convexity of the cornea, but also on convexity of the lens ; and having no hope of being able to effect any alteration in the structure of the lens, my attention was directed to the iris, which I found to be, in such persons, generally much dilated. It then occur- red to me that contraction of the iris has the effect of apparently lengthening the convexity of the cornea, which approaches a circum- scribed plane, that permits the rays of light to enter only in a straight line. The effect of this is obvious. The length of vision hereby ne- cessarily becomes increased, and distant objects are brought within its range. It therefore struck me, that if we could discover any sub- stance which could be so applied as to contract the iris, one cause of the defect of short-sightedness would be remedied. The result, I am happy to say, has been most satisfactory. In the first instance, I ap- plied the extract of ginger, which was rubbed for five or ten minutes over the whole forehead, with the view of acting upon the branches of the fifth pair of nerves. Afterwards, I substituted a concentrated tincture of ginger, of the strength of one part of ginger to two parts of spirit of wine, decolorized by animal charcoal. The success of this application was remarkable. In many cases it had the effect of doubling the length of the vision. In some persons I found the iris was not much dilated, but very torpid. In these cases I applied the concentrated tincture of pepper, made of the same strength, and in the same manner as the tincture of ginger. This I used until I ob- served that the iris had obtained a greater power of contraction and dilatation, after which I had again recourse to the tincture of ginger. This plan of treatment has been attended with the most signal suc- cess, and persons who were extremely short-sighted have very soon been enabled to lay permanently aside their concave glasses. The best method, I may observe, of testing the improvement of the sight during this treatment, is not by taking a printed book, and holding it near, and then at a greater distance from the eyes ; this range of vi- sion is much too limited. It is better to fix. the attention of the pa- tient upon a distant object, such as the brass key-hole of a door, and by stepping some paces backwards, so as to place himself at a greater distance from it, he will soon discover the progress he is making. So important a discovery as this will, I hope, be fairly tested by the members of our profession, who may rely on the success of the treat- ment I have recommended, if it be only judiciously and carefully car- ried out. It is possible that the advantage derived from the tincture, as above described, may be ascribed to the alkaloid principle of piperin which is held in solution in the tincture of pepper. — The Chemist. Success in the Medical Profession. The following extract is from Professor Ware's introductory lecture to the class in the Massachusetts Medical College, as published in the Boston Medical and Surgical Journal. Parallels to the characters here so graphically hit off, are to be found in every community : " One man who succeeds is a boaster. He is a living advertise- ment of his own recommendations. His talk is of great cures, of 28 238 SELECTIONS. which he tells long and marvellous stories ; of the distinguished and well-known families whose attendant he is ; of the great distance from which patients come to seek his advice. He loses no opportu- nity of impressing on mankind his great skill and his extensive re- putation. There is another who develops his self-complacency in a different manner. He is lofty and oracular. His style of discourse is that of a superior; he cherishes something of the old mystery in which the profession used to delight. He talks obscurely ; he en- trenches himself behind technicalities, is magnificent upon trifles ; he even deals out his pills with an air of majesty. There is still another who is irritable and arbitrary ; who is a tyrant in the sick room ; who resents every little disobedience as a personal insult, and regards the natural expressions of doubt and anxiety as so many reflections on his professional character. As his opposite, there is one who is all gentleness ; who always assents — never finds anything or anybody in the wrong ; who courts the patient, the friends and the nurse — and has a flattering word for each ; who is all things to all ; who is a syco- phant and almost a hypocrite — whose countenance is the index to his character : ' Eternal smiles his emptiness betray, As shallow streams run dimpling all the way.' Then there is, on the one hand, the man of invincible taciturnity, in whom silence is taken by some as the sign of wisdom ; and on the other, the man of invincible loquacity, whose never-ending stream of words flows on as innocent and as empty of meaning as the babbling of a summer brook. " In this picture there is perhaps a little exaggeration of what wTe meet in actual life ; 3ret men exhibiting these various peculiarities do oftentimes succeed. Their currency, however, is usually with a limited class ; those who like one, naturally dislike his opposite. But there are some physicians whose mode of intercourse with the sick recommends them equally to all, independently of any mere reliance on their medical skill." — St. Louis Med. and Surg. Journal. Cod Liver Oil in Phthisis Pulmonalis. Dr. Levick, resident physician in the Pennsylvania hospital, pub- lishes in the January No. of Amer. Jour. Med. Sciences, fourteen cases of pulmonary disease in that institution, in which cod liver oil was used. The following are his conclusions respecting its effects. [Med. and Sur. Jour. " If I mistake not, it is highly important that the real value of this remedy should be soon determined. Exaggerated impressions of its worth have no doubt been made, to be followed by their necessary disappointments. All the results promised by some writers from it, have certainly not followed its use in the hospital, nor in a large number of cases in private practice, which, through the kindness of his medical friends, the writer has had an opportunity of closely watching. On the other hand, we can positively say, that most of SELECTIONS. 239 our patients, while using the oil, have increased in flesh, in weight, and in strength ; that with most of them there has been a diminu- tion of cough and of expectoration ; that with some of them, hectic and rigors have entirely disappeared ; and that there have been some so benefitted as to be able to resume their former occupations. We can also understand that it may so strengthen the patient as to enable him to make use of those hygienic means which are so efficacious ; that it may thus, perhaps, indirectly cure consumption. Again, in phthisis, as the local affection is but a part of the disease, if the gene- ral health continue to improve, we may hope that the diathesis will be, in the course of time, thoroughly changed, and thus, perhaps, cod liver oil may cure consumption. But these suppositions are merely such ; the assertion of its good, but limited effects, are posi- tive. The first may happen, the last have happened. " An objection has recently been made to the use of cod liver oil, that it produces pulmonary congestion and haemorrhage. This is a plausi- ble suggestion ; we have not found it to exist in practice. The only instance in which an attack of bleeding could be positively traced to the use of the oil, was that of a patient admitted for haemoptysis, who, after having been in the house for several weeks, with great improvement of his haemorrhagic symptoms, was placed on the use of the oil from some suspicious physical signs. Nausea and emesis were produced by the oil, and a haemorrhage followed the act of vo- miting. This may suggest a caution under similar circumstances. " It will be seen that in no instance did any decided benefit arise from the oil until it had been used at least four weeks ; it is equally important to observe, that to be of any permanent benefit, its use must be persisted in for a long time, even after the most striking symptoms of disease have in a great measure disappeared ; a fact, of which we have always endeavored to impress the importance on our patients at the time of their dismissal from the hospital. " Although then, in conclusion, our experience has not been quite so gratifying as has that of some others, yet the writer is fully pre- pared to say, that he believes cod liver oil to be by far the best remedy for phthisis pulmonalis of which we have at this time any knowledge ; and that to neglect its use in cases of this disease, unless there be a strong contra-indication. is, under existing circumstances, both injudi- cious and culpable." Of the candidates examined for admission into the naval service as assistant surgeons, the following from Virginia have been found quali- fied, viz : Frederick Horner, Jr., Warrenton. James B. Whiting, Norfolk. Randolph Harrison, Cartersville. John C. Coleman, Halifax courthouse. J. Page Hopkins, Winchester. 240 COMMUNICATION. The Medical Society of Clarke County, Virginia, Met, by appointment, on the 24th March 1851 — Present, Drs. Little, Randolph, Harrison, Nelson, Kownslar, Barton, Neill and Haynes. The society was called to order by the vice-president, Dr. Kownslar, and the minutes of the preceding meeting were read. The committee appointed at a previous meeting to draft a constitu- tion and by-laws for the society, reported through their chairman, Dr. Haynes, which report was received and unanimously adopted. On motion of Dr. Randolph, the society agreed to exempt certain members from all expenses, otherwise required by the by-laws. The society then elected the following officers for the ensuing year, viz : Dr. Randolph Kownslar, President. Dr. J. F. Fauntleroy, Vice-president. Dr. S. S. Neill, Recording Secretary and Treasurer. Dr. H. T. Barton, Corresponding Secretary and Librarian. Dr. Haynes, } Dr. Randolph, > Publishing Committee. Dr. Harrison, ) On motion, a committee of three (Drs. Randolph, Harrison and Kownslar,) was appointed to prepare a code of ethics for the society by its next meeting. The society then appointed Dr. J. F. Fauntleroy as its delegate to the National medical association, to meet in Charleston, South Caro- lina, on the first Tuesday in May next, and Dr. Kownslar alternate. The committee for the purpose then announced typhoid fever as the subject for the next discussion, and appointed Dr. Barton to write an essay on Placenta Prcevia, to be read at the next meeting. On motion, the books presented to the society by Dr. Nelson were received, and the thanks of the society returned. On motion, it was ordered that the proceedings of this meeting be sent to the " Stethoscope" for publication. J. A. HAYNES, Chairman of Committee on Publication. Hygienic Virtues of Mustaches. — Our contemporary, the Union Medi- cate, announces the discovery, by the National and Military Gazette of London, (a journal with which we are unacquainted,) of certain hy- gienic virtues in mustaches. These consist in the hygrometric and thermometric properties possessed by the human hairs — so that, when growing below the nostrils, they absorb the moisture, and prevent cold air from entering the respiratory passages. Statistics prove their value, as they prove everything else. In the regiments that wear mustaches, pulmonary affections, colds, &c, are unknown ; whilst in the regiments in which the men shave, catarrhs, pneumonias, coughs, &c, are common ! — Edin. Monthly Journal. THE AND No. 5. RICHMOND, MAY 1851. [Vol. L Remarks on the Pathology and Therapeutics of Colica Biliosa, or Bilious Colic. BY J. J. THWEATT, M. D., PETERSBURG, VA. The frequency and formidable character of bilious colic invest it with peculiar interest to the Southern practitioners of medicine. Notwithstanding the intense investigation which has been made rela- tive to its pathology and treatment, it must be conceded that much obscurity still rests upon these important points. The influence of the schools of Hamilton and Rush on the practice of medicine in this country, has been the cause of grave errors. No branch of the science of medicine has suffered more from this influence than pathology ; and, we will add, that in no disease has the fallacy of the principles of those schools been more conspicuously shewn, than in the treatment of bilious colic. The light which has been shed upon the nature of diseases of the intestinal canal by the so-called anatomico-pathological school of medicine, enables us in a manner to throw off the shackles of those high authorities ; and, instead of a vain and unprofitable searching after the remote and proximate causes of morbid action, to study, "scalpel a la main" the effects of disease in tissues, organs and systems of organs. It is by this method alone that our science can ever reach certainty. According to the etymology of bilious colic, the phenomena which characterize the affection depend upon a vitiated secretion of the liver, (acrid bile,) which, passing into the intestinal canal, produces spasmodic action, vomiting, &c. In almost all the systematic works on the practice of medicine, and by medical men of the highest professional eminence, the opinion is pertinaciously maintained, that the essential features of bilious colic are connected with a depraved condition of the biliary secretion and spasmodic action of the muscular tissue, which enters into the composition of the intestinal tube, the liver being in an engorged condition; hence all of the symptoms of the disease depend on an engorgement of the liver, defective and depraved secretion, and muscular irritability. We are utterly opposed to this opinion of the nature of this disease; we believe that it has been the source of great mischief, and should be 29 242 THWEATT ON BILIOUS COLIC. discarded by medical men. With respect to the pathology of bilious colic, we are prepared to maintain the following propositions : 1st. That bilious colic is eminently an inflammatory disease. 2nd. That all of its more prominent features arise from an inflammation of the mucous membrane of the pyloric region of the stomach and superior portion of the intestinal tube, especially the duodenal portion, accompanied with spinal irritation. The force of the remote or proximate causes of the disease is spent upon this portion of the intestinal mucous membrane, exciting inflammatory action. According to this pathological view, the symptoms of the disease are susceptible of easy explana-. tion. No difficulty is experienced on the part of the practitioner to locate them, and apply the proper remedies. In the more violent forms of this disease, the patient is seized with violent pain in the epigastric region, accompanied with intense heat, nausea, vomiting, and obstinate constipation, the irritability of the stomach being sometimes so great that nothing liquid can be retained for the shortest time, incessant vomiting, not of acrid, bilious matter, as is generally stated by authors, but of thin, acid mucous, secreted from the gastric mucous membrane. Vomiting of bile in this disease is far from being so common as is thought by many writers. The stomach is irritable, which constitutes one of the most annoying s}'mp- toms to the patient, the circulating system soon becomes involved, and you have a full, strong, bounding pulse, redness of the face with constant flushings, accompanied with more or less headach ; the ner- vous system soon manifests derangement, extreme jactitation, cries of alarm follow, the patient often complains of pain in the back, and, ■on examination of the spine, tenderness along the dorsal vertebras is produced by pressure, (the abdominal muscles are spasmodically con- tracted, especially the rectus.) The above description appertains to the severe cases of bilious colic ; but there is another class of cases of this disease of quite a different character — the patient com- plains of a dull pain in the region of the stomach, extending along the posterior border of the liver ; there is no appetite, tongue thickly coated, slight jaundice, pulse slow but strong, slight pain on pres- sure, constant nausea but no vomiting, or great irritability of the sto- mach, constipation not so obstinate as in the more violent cases ; but what is peculiar to this form of the disease is, that no relief is af- forded by the evacuations from the bowels ; these evacuations shew the want of proper bilious secretion, being of a brown or whitish character, sometimes slightly tinged with bile. The character of the constitutions of persons affected with this form of bilious colic is leu- cophlegmatic ; it is frequently to be met with in those localities where intermittent and remittent fevers prevail, and in seasons sub- sequent to long droughts. The more prominent phenomena of bilious colic are admitted by many authors to be the result of inflammatory action; but it is contended that they are the effects of previous biliaiy derangement, of acrid bilious secretion. The post hoc propter hoc ar- gument has been, sa}rs a recent writer, the bane of the science of medicine from time immemorial. We find the power of this false mode of reasoning fully exemplified in the minds of s\~stematic wri- ters on bilious colic. THWEATT ON BILIOUS COLIC. 243 The symptoms exhibited in a case of bilious colic are the result of inflammation confined as we have stated to the mucous membrane of the pyloric region of the stomach and superior portion of the digestive tube ; and we are strongly inclined to the opinion that the mucous membrane of the duodenum is the first to be attacked. We wish to direct particular attention to this point : the symptoms which mark inflammation of this portion of the intestinal mucous membrane, as given by the most distinguished pathological observers on the Conti- nent of Europe, corresponds exactly with those of bilious colic in a large majority of cases. M. Piorry, in his Traite de Medicine Pra- tique, says that duodenitis is characterized by a dull, circumscribed pain extending from the lower border of the liver to the pit of the stomach. On percussion mattity is detected in this region — the pain is also exasperated on pressure. We do not intend to confine the pathology of bilious colic exclu- sively to the duodenum, for we are well aware that the pathology of this portion of the digestive apparatus is yet to be made ; our opinion is that the disease, in a large number of cases, commences here. Here is the veritable point de depart of the malady, the inflammatory action extends itself to the biliary ducts, the bile ceases to flow in the intes- tinal canal, or if it does, in small quantities. From the same cause fol- lows the accumulation of bile in the lobules and cells of the liver, engorgment and inflammation of that viscus, and arrest of secretion. Jaundice is almost an invariable symptom in bilious colic. In truth, from our short observation, we have never seen a violent or mild case of this disease without some appearance of jaundice. Now, is not this symptom satisfactorily explained by the pathological condition of the duodenum? M. Broussais was the first to draw the attention of medical men to this cause of jaundice. M. Andral has published some valuable papers in the Archives de Medicine in corroboration of this view. The acrid and stimulating quality of the bile, upon which so much stress is laid, becomes so from accumulation and confine ment; and if deficient secretion occurs, it arises from engorgement or accumulation of bile in the lobules or cells of the liver, the latter being the proper secreting organs of that viscus. If the symptoms are not sufficient to prove that bilious colic is an inflammatory disease, we can confidently appeal to the condition of the blood, and the au- topsic phenomena, as furnishing incontestable proofs of the fact. In all of the cases of bilious colic which have come under our observa- tion, whether in strong, robust, or weak and debilitated constitutions, the examination of the blood shewed an excess of fibrine ; and this is regarded by the highest authority in our science as indicative of inflammatory action. What are the results of dissection? The mu- cous membrane of the stomach and superior portion of the alimen- tary canal is found in these conditions, viz : deeply congested, or softened or ulcerated ; the liver, in a large number of instances, is engorged, enlarged, and sometimes presents the hob-nailed appear- ance— a true sign of intense phlogosis. A case occurred recently in the practice of one of our medical friends, which proved fatal, and on a post mortem examination, the mucous membrane of the stomach 244 THWEATT ON BILIOUS COLIC. was not only softened, but there was ulceration in different parts of the same membrane of the small intestines, which were contracted, and in some parts so much so, as not to permit the passage of a com- mon bougie — the liver was engorged and augmented in volume. We have stated that symptoms of spinal irritation were often pre- sent in this disease. This is a point which has been entirely over- looked by authors ; our attention has been particularly drawn to it, from the fact that in the first case of bilious colic which fell under our observation, spinal irritation was well manifest, the pain in the back was intense, and caused incessant complaint from the patient ; there was evident tenderness on pressure, the constipation in this case was very obstinate, cramps and contraction of the abdominal muscles and inferior extremities very annoying to the patient. From more extended observation we are convinced that spinal irritation enters as an impor- tant element in the pathology of bilious colic. Treatment. — There is no disease in which more remedies have been recommended and tried than in bilious colic ; the catalogue of emet- ics, cathartics and narcotics have literally been exhausted in the vain endeavor to find one that would answer the indications — which are, according to the old notions of the nature of disease, to evacuate the alimentary canal, and restore the biliary secretion. Under this hepa- tic delusion, calomel, oil and turpentine, croton oil, tobacco injections, et id omne genus, have been used with a lavish hand ; under this perturbatory plan, of treatment, which we regret to say is the one still adopted by many physicians, the inflammation, the main cause of the symptoms, is increased instead of diminished ; and thus many cases which were mild in the commencement become obstinate and intract- able. To those who are not laboring under this hepatic delirium with regard to the true nature of bilious colic, the indications of treatment are plain and simple. Regarding the disease as essential^ inflamma- tory, the first remedy to be used is blood-letting. We do not hesi- tate to affirm that in no disease, without exception, is the lancet more demanded, and in none is the use of it followed by more gratifying results. To reap the full benefit from this remedy, it should be used to the extent of making a decided impression on the constitution : the patient should be made to sit up in bed, a large orifice made, and the blood permitted to flow until syncope, sickness of stomach or palor of the countenance indicate that a sufficient quantity has been taken. The effect of bleeding in this disease is sometimes magical : we have seen cases where the irritability of the stomach, vomiting, pain, mus- cular contraction — all yielded to free bleeding. One of the most emi- nent practitioners of our city related to us the history of a case of bilious colic of frightful severity, in which the constipation gave way under bleeding. We have often seen cases yield, after free bleeding, to mild laxatives. Many authors admit the value of blood-letting, but they say it should be confined to the incipient or early stages of the disease, and that it is inadmissible after the lapse of a certain num- ber of hours or days. This idea of bringing the use of remedies to a rigid mathematical limit, is a pernicious one, and if carried out, is calculated to produce the most pernicious results. The lancet should THWEATT ON BILIOUS COLIC. 245 be employed in all stages of the disease when there are manifest symptoms of inflammation, or, to use stronger language, in all cases where the constitution of the patient will admit of its legitimate use. We have not the hardihood to say, that purgatives and emetics will not cure the disease ; for morbid action will yield under the most op- posite treatment; but we do say, that the practitioner who relies on these remedies will be disappointed : he therefore should not be sur- prised if his repeated efforts prove abortive and his patient dies. Let a post mortem examination be made in a case of bilious colic that has been treated by purgation, and we venture the assertion, that the most prejudiced opponent of the lancet will admit its indispensable necessity. In persons of strong and vigorous constitutions the bleed- ing may be repealed with benefit. . We have found, however, that after free blood-letting, the local abstraction of blood bv leeches and cups, repeated three or four times, according to circumstances, will remove all inflammatory symptoms. In old persons and those of a leucophlegmatic habit, and especially those who have been subject to the multiplied forms of dyspepsia, the local abstraction of blood is our chief reliance ; under these circumstances leeches in the epigas- tric and right hypochondriac region will produce most beneficial effects. Topical depletion therefore is a valuable adjunct in the treatment of bilious colic, and should not be neglected. Emetics. — This class of remedies were and are still much lauded by the advocates of the old pathology of bilious colic. To administer an emetic was the first step in the treatment of the disease ; but, ac- cording to the view we have taken of the nature of the disease, eme- tics are rarely indicated — cases are rarely met with in which matters capable of offending the intestinal mucous membrane are not thrown off long before medical aid is solicited. The great difficulty to sur- mount here, is to allay vomiting ; emetics would only tend to increase it, and likewise increase the inflammation. In old dyspeptic persons, after a free indulgence of the appetite, a mild form of this affection is induced; in such cases we have found a gentle emetic to act benefi- cially ; it is only in cases such as described that we ever prescribe emetics. Calomel and, Opium. — After depletory measures, a large dose of calomel and opium, say from 10 to 15 grains of the former to 1 or 2 of the latter, followed in four or five hours by a dose of oil or any other mild laxative, will act in the happiest manner. It is a common practice in our day to resort to large and repeated doses of calomel, regardless of pathological indications. This medicine is looked upon as magnum bonvm dei, which is to answer all purposes, fulfil every in- dication, cure every disease. Calomel is a valuable remedial agent, but it should be given at a proper time and in a proper manner. The full therapeutic benefit of this remedy cannot be obtained as long as high inflammatory action exists in the system ; it may calm irritation, it may prevent the results of inflammation, it may, it does remove the results of the inflammatory process, but that it possesses the power of controlling high inflammatory action, we deny. How often does it happen that this medicine is administered dose after dose in 246 THWEATT ON BILIOUS COLIC. inflammatory diseases without producing any effect but active purga- tion or constitutional irritation. Apply the antiphlogistic means, and the calomel will shew its proper operation immediately. The worst cases of salivation are brought about by this means. To obtain then the full benefit of this remedy, it should be taken after the more in- flammatory symptoms have been subdued by general or local deple- tions. At this period a dose of calomel, repeated in four or six hours, will relieve the engorgement of the liver and portal circulation, and assist measurabl}r to allay the general irritation of the constitution. Combined with opium, its curative powers are increased ; opium acts not only in soothing irritation, but as a relaxative to the constricted muscular coat of the intestines. We may remark, en passant, that opium exerts a puissant influence over inflammation of the mucous membranes. In very obstinate cases of bilious colic, calomel may be carried so far as gentle ptyalism — intense salivation is a result to be deprecated in all cases. Tartar Emetic. — The high laudation which has been bestowed upon this article of the materia medica, as an antiphlogistic, by the patholo- gists of the Continent of Europe, and particularly those distinguished authorities, Andral, Louis, Chomel and Bouillaud, has induced many practitioners to resort to its powers in the disease under consideration. Close observation has convinced us that however beneficial tartar emetic may be in inflammatory diseases on the Continent of Europe, in our climate it should be used with a cautious and sparing hand. In uncomplicated inflammation of parenchimatous structure, it is trul}7" a heroic remedy, but when the mucous membrane becomes involved in the inflammatory process, its action is pernicious. That the violent symptoms of bilious colic may be controlled by its action, we are not disposed to call in question, but care should be taken, that in con- trolling these symptoms you do not bring about, if not gastro enteri- tis, a slow form of sub-inflammation, with its concomitants, softening and ulceration of the intestinal mucous membrane. In our opinion, tartar emetic should be discarded from the list of remedies in bilious colic. Blisters. — Blisters during the early stage of the disease are wholly inadmissible, and we must confess we are not ver}r partial to these agents at any period of the disease. Our experience of blisters in bi- lious colic will not permit their recommendation ; the}'' are always very objectionable to the patient, and almost always, when used, in- crease the irritation of the system. When the disease has been pro- perly treated, there is rarely any necessity for blistering. However, in some cases, when there are indications of a slow sub-inflammatory ac- tion going on in the mucous membrane, they may be resorted to with some benefit. Upon the whole, their curative agency is very limited in this affection. Adjuvants. — In giving the above appellation to the agents we shall introduce, we do not intend to convey the idea that we think lightly of their effects; on the contrary, we hold them in high estimation, and regard them as playing a very important part in the cure of the dis- ease. Among the most important articles of the list of adjuvants are THE PANCREATIC JUICE IN DIGESTION. 247 castor oil, rhubarb and magnesia, and especially a combination of sul- phate of magnesia, sulph. of postash, bicarb, of soda, a small quan- tity of the tinct. of opium, syrup of orange peel in some aromatic menstruum. This makes a pleasant mixture— it acts gently on the bow- els, correcting, at the same time, any acidity that may be present in the pritjtKB vice. Enemas are useful ; in order to render them more ef- fectual, oil and turpentine may be added ; sometimes active purga- tives are required, as a decoction of aloes, &c. When the patient complains of flatulence, we have found the assafcetida enema to act like a charm. Great thirst and irritability being very troublesome symptoms, no remedy is more effectual in removing them than ice ; the patient should be allowed to eat plentifully of ice well beat up. It often is the case that patients are permitted to take large draughts of water. This practice produces no benefit, and is highly injurious. The application of flannels, wrung out of hot water, milk and bread poultices, particularly hop poultices, to the abdomen, is not to be de- spised. We have derived more advantage from the hop poultice than any other. It is peculiarly soothing, from its anodyne properties, to re- lieve the pain in the back, which is very annoying, after topical deple- tion by cups to the painful region. The application of the chloroform liniment to the spine will answer a valuable purpose. We have often used the chloroform with admirable effect. The veretria ointment sometimes acts well, but it does not merit the encomium which has been bestowed upon it as a nervine. When the heat of the stomach is very great, accompanied with intense irritability, we have found nothing so grateful to the patient as the application of ice to the epi- gastric region. It should be pounded and put into a bag, and allowed to remain on as long as it proves grateful and pleasant to the patient, and should be removed immediately on the least complaint of chilli- ness. It is almost superfluous to add, that the diet should be anti- phlogistic. In no disease is a properly regulated diet of more import- ance than in bilious colic. The Pancreatic Juice in Digestion. Mr. Editor : I send you an article upon the importance of the pan- creatic juice in digestion. It was suggested upon looking over notes which 1 took whilst attending a course of lectures upon physiology, delivered by C. Bernard of Paris, during the year 1848. I am not aware that the views here given have been hitherto published in this country. Carpenter, in the last edition of his work, alludes to its property of digesting fatty matter, but does not take into considera- tion its other properties. I take some interest in this subject, as I had the pleasure of witnessing the experiments of M. Bernard, which sa- tisfied me of the truth of his views. Yours, &c, M. P. SCOTT. 248 THE PANCREATIC JUICE IN DIGESTION. Bernard was the first to discover the true functions of the pancreas, which, if his conclusions are sound, is one of the most important or- gans concerned in the process of digestion. By his patient investiga- tions and philosophical deductions, he has cleared up one of the mysteries of ptrysiology, concerning which all has been heretofore mere speculation. It is true that his conclusions have been deduced from experiments made upon the lower orders of animals; but by shewing the identity of the different fluids concerned in digestion in all of the lower orders, he was justified in coming to the conclusion, by analogical reasoning, that the same phenomena exhibited by them were also performed in the human system. He has proved thus the importance of searching for truths in medical science, by experiment- ing upon animals, and upon the facts thus gained, establishing the physiological laws which regulate the human system. Upon a just and accurate knowledge of these laws, it is only possible to establish a sound system of practice, without which all must be uncertainty or empiricism. The old practice, of first concocting a theory and afterwards search- ing for facts to sustain the preconceived opinion, has been discarded — the order is reversed. The inductive system of reasoning obtains now in this science as in all others, and all theoretical notions that are not founded upon facts are cast aside — we obtain our facts, and upon them establish our theories. This may be a slow method ; but it is the only sure one. It must be confessed, however unpalatable it may be, that we are far behind our brethren on the other side of the At- lantic in our researches in physiology and pathology. We are satis- fied with folding our arms and quietly waiting for all improvements in our science which may be sent to us. These we receive and swal- low with avidity, or speculate vaguely upon, or reject if they do not agree with the theories taught when we attended lectures. None think the experiments upon which they have been founded worthy to be repeated, or of making experiments to test the truth of those theories created in the imaginations of the speculative class of physiologists. But. we have an offset, and flatter ourselves that if the French excel us in the science of physiology and are the best pathologists, we are the best practitioners. A vain illusion — for what kind of practice must that be that is not founded upon facts drawn from physiology and pathology, upon a proper knowledge of the functions of the different systems and organs of the human being, and the changes which are produced by disease. In the same vein and in the same manner the swarm of quacks and charlatans who overspread the land boast that they excel us. They point to the results of their systems — laugh at phy- siological facts, and care not to know whether a human being has a liver, so that he is possessed of a stomach or sac to receive their drugs and nostrums. They go ahead. The French are the most cautious practitioners, for the same reason which induced Frere Jacques to give up the operation for stone in the bladder after the anatomy of the parts was taught him. He never knew before the imminent risk his patients ran of losing their lives if a blunder was committed. We are more heroic, bolder practitioners — not better. THE PANCREATIC JUICE IN DIGESTION. 249 The process of digestion has alwa}7s been one of the most inter- esting subjects in physiology — no part of the science has perhaps so much engaged the attention of the profession in all ages, and there is none about which there has been so much speculation, nor indeed at the present time has it ceased to engage the attention of scientific men — the field for speculation and experiment is still open. Certain facts have however been established, by which ancient as well as more modern theories have been overthrown. The opinions of some of the older writers, that the stomach was the only organ for digestion, and that the liver and pancreas, like the kidneys,* were merely secernants, destined to separate certain noxious principles from the blood, has been long since exploded. More modern authors have adopted the theory of chemical solution put forth by Spallanzanne. These suppose that all kinds of food are reduced by the action of the gastric juice to one uniform, homogene- ous semifluid ; that all kinds of aliment produce the same nutrient principles which, submitted to the action of the gastric juice, becomes chyme, and that this chyme is changed by the action of the bile and pancreatic juice into chyle, which is now ready for absorption by the lacteals. This last is the opinion of Beaumont, deduced from his ex- periments upon a patient having a fistulous opening in the stomach. This opinion has been proved by modern experimenters to be errone- ous, as also the opinion that chyle was formed by the action of the bile and pancreatic juice upon chyme — thus overthrowing the asser- tion formerly made that the chyle contains the essence of all kinds of nutriment. Almande was enabled to establish that all alimentary matters were not digested in the stomach — his observations were made upon a patient having an intestinal fistula, through which he was enabled to see certain kinds of food pass, and to extract those which had not been affected during their passage through the stomach. Subsequent experimenters have established this. Thus the glucose class of aliment is not acted upon by the gastric juice; this fluid does indeed act upon cane sugar, changing it into grape sugar, but here its action ceases, but upon amidon it has no effect. How this class of substances was ultimately disposed of has been a subject of much speculation and experiment. Some have supposed that the saliva was the digestive agent, that by its action the nutritive materials were separated ; others, that the stomach was the organ for this purpose, and that ulti- mately they were changed into oleaginous compounds and formed part of the constituents of chyle. It would appear now that the stomach digests the azotized class of food, or rather that the first stage of the digestion of that class is per- formed in that organ, and that their digestion is completed in the du- odenum by the operation of the bile and pancreatic fluid. The agen- cy of the pancreatic juice in digestion has been until recently con- founded with the bile, and many of its effects attributed to that secre- tion. Thus, when it was ascertained that fats and oils were not di- * This was the opinion of Blondlow. 250 THE PANCREATIC JUICE IN DIGESTION. gested by the agency of the gastric juice, it was supposed by Muller and Brodie that the digestion of these matters was performed by the bile; it was not until the experiments of Bernard that its true func- tions were discovered. Physiologists for the most part have held the opinion that the pancreas was merely a salivary gland — some few thought that its office was to supply albumen to the system when there was a deficiency of this principle in the blood. They supposed that the pancreatic juice contained albumen, as it was seen to coagu- late when heat was applied, or a strong acid added. Both of these opinions have been proven to be erroneous, but that the office of this secretion is to digest certain alimentary substances which are not acted upon by any other digestive fluid ; and also by its union with the bile to complete the digestion of the azotized class which have been first submitted to the gastric juice. The pancreatic juice is a colorless, slightly viscid fluid, con- stantly alkaline in its reaction ; it is coagulated by heat. Its ten- dency to putrefaction is very great, and, for this reason, should be always experimented with very soon after being taken from the duct. After being kept for a short time, it ceases to act upon alimen- tary substances submitted ; its appearance alters, it loses its consist- ency, and will not coagulate when heated. The quantity of the secretion is influenced by the condition of the organ, as is also its quality; thus, when the pancreas is irritated or slightly in- flamed, there is a much larger flow ; but it will not act as that secreted during a normal condition of the gland ; if, however, the in- flammatory action is great, the secretion will be entirely arrested ; it is similar in this respect to the stomach. Those who considered the pancreas as a salivary gland, founded their opinion upon the similarity of the pancreatic juice'to saliva. The action of each upon amidon was supposed to be the same, and referred to as evidence of the identity of the two secretions. Had they been more careful in making their observations, they would have seen that there was some slight difference in the action of the two secretions upon this substance. For example, saliva changes amidon first into dex- trine, and subsequently into sugar of second class or grape sugar, and, finally, into lactic acid, whereas the pancreatic juice only changes it into grape sugar. This difference of itself should have raised some doubt as to the identity of the two. Magendie, in speak- ing of the action of saliva, says : " If by an opening into the parotid duct, we remove the fluid of the parotid gland before it reaches the mouth and place it in contact with starch, no conversion into sugar takes place. It is the same also with the saliva drawn from the maxillary ducts in the dog. There is, then, something peculiar in the buccal saliva dependent upon all its constituent principles. " Here then, is a wide difference between the salivary glands and the pan- creas ; for the pancreatic fluid of itself effects the transformation. The first class of substances which are acted upon by the pancre- atic fluid to which I shall refer, is the amylaceous, or that class, which is capable of undergoing transformation into grape sugar. That the saliva does not, under ordinary circumstances, effect this change THE PANCREATIC JUICE IN DIGESTION. 251 can be easily established ; indeed, that the action of saliva is me- chanical and not chemical, and that its place could be supplied with pure water, is now, I believe, the received opinion. These substances undergo no change in the stomach, as may be seen by giving amidon to a dog, and afterwards extracting the contents of the stomach, through a fistulous opening, and testing them. This will also be seen to be the case, if it is digested out of the body with pure gastric juice. If this substance be followed, it will be seen that it disap- pears in the duodenum. Now, the only secretions which are poured into the duodenum, are the bile and the pancreatic juice, and to' one of these must the disappearance of the starch be due. That it is not owing to any action of the bile, may be proved by digesting it with pure bile when no transformation takes place; and, we might now reason, that it must be the pancreatic fluid which digests it, that being the only remaining digestive agent ; but, a more conclusive proof is, that if the duct leading from the pancreas be tied, and the contents of the duodenum of an animal previously fed upon starch be examined, it will be seen that no change has been made upon it ; and, lastly, if starch is digested with pure pancreatic juice, a trans- formation into grape sugar will result. That it is now fit for absorp- tion is most probable ; as if a solution containing grape sugar be in- jected into a vein, no trace of it can be discovered, either in the blood or in any one of the secretions, thus shewing that it has been assimi- lated, so that it is reasonable to infer that this class of substances do not undergo any further change, as now they are ready for assimila- tion. Of its agency in the digestion of fatty matter. It was, for a long time, the received opinion, that the bile was the agent designed for the digestion of fatty matter. This opinion was founded upon expe- riments made by Muller, and it was not until his experiments were repeated by Bernard, that it was found to be fallacious ; for, if pure bile be added to oil free from acidity, no emulsion will be formed ; and, if the mixture be allowed to remain a short time, there will be a complete separation, the oil floating as pure and unchanged as it was before it was mixed with the bile. If, now, a small quantity of pan- creatic juice be added, an emulsion will be formed immediately, simi- lar in appearance to chyle. From this it might be inferred that the bile, experimented upon by Muller was not pure, or that the oil was rancid ; for bile has a peculiar action upon rancid oils, forming with them a kind of soap. Here may have been a source of error; most probably, however, that distinguished physiologist obtained the bile from the biliary duct after it had been joined by a pancreatic duct. In the dog there are two ducts leading from the pancreas, one joining the ductus choledocus, the other entering the duodenum an inch lower; so that the error was natural enough if the bile was taken from the biliary duct after being joined by the pancreatic duct, giving as the result all the phenomena justly ascribable to the pancreatic juice. In order that the experiment should succeed, it is necessary that the pancreaclic juice should be perfectly fresh, and the oil free from acidity. When the experiment is performed out of the body, the 252 THE PANCREATIC JUICE IN DIGESTION. emulsion will have an acid reaction. This is not the case in the in- testine, for it does not lose its alkalinity. This difference is probably due to the oxygen of the air, there being a decomposition of the oil into glycerine and oleic acid, the latter being free gives to the emul- sion an acid reaction. The gastric juice has no effect whatever upon the oils as any one may convince himself by obtaining pure gastric juice from the stomach of a dog, and subjecting the oil to an artificial digestion at the common temperature of the body. It will be seen that the oil will remain unchanged. Thus it has been shown that neither the gastric juice nor the bile, when experimented with out of the bod}', has any power in digesting the oils, but that the pancreatic fluid forms with them an emulsion similar in appearauce to chyle ; but, it may be argued that, although such are the results of the experiments as performed, that in the in- testine the action of these fluids may be different, or that the secre- tions from the intestine may alter in some way their operation. The following experiment is, I think, conclusive: If a rabbit be fed upon oil, and its abdomen opened during full di- gestion, no trace of the oil will be found, but the lacteals will be seen loaded with chyle. Now, take another rabbit, ligature the pancreatic duct, and feed it in like manner upon oil ; after a sufficient time has elapsed, open the abdomen as before, when the oil will be found unaltered in the intes- tine, nor will there be seen an}'- appearance of chyle in the lacteals From these facts two conclusions may be justly drawn ; first, that the oils and fatty matters are solely digested by the pancreatic juice ; and secondly, that chyle is not the essence of all kinds of 'alimentary mat- ter, but is formed by the action of this fluid upon fatty matter; for we have seen that none of the other secretions act upon oil ; that that of the pancreas forms an emulsion with it similar in appearance to chyle ; and lastly, that no chyle is formed if the duct of the pancreas has been previously tied. The pancreas then is the chylopoietic gland. The pancreatic fluid changes sugar of milk into sugar of grape ; there being this difference between the two, that the former will not undergo fermentation when yeast is added to a solution containing it. The active principle of the pancreatic juice, to which the changes induced upon the various substances submitted to its action is due, is an organic matter which can be isolated ; for a solution containing this organic matter will effect the same changes as the pure fluid itself; it has been named clujloyoiene, from its property of forming chyle ; it may be precipitated by alcohol, and afterwards dissolved by water. There is also another peculiar principle, which has never been isolated, which will be alluded to further on. Pancreatic juice aids also in completing the digestion of the azo- tized class of alimentary substances which have been subjected to the action of the gastric juice and bile. This class of alimentary matter, after being introduced into the stomach, is dissolved by the gastric juice, and forms a new compound, the lactate of fibrine. When this THE PANCREATIC JUICE IN DIGESTION. 253 compound is introduced into the duodenum, a further change takes- place when it is mixed with the bile. According to Platncr, there is a general play of chemical affinities, double decomposition takes place, and two new compounds are formed — lactate of soda and a cho- leate of fibrine ; the latter is insoluble, and must undergo a further change before it is fit for absorption and assimilation. This is effected by the intestinal juice, which is the result of the union of the pan- creatic and hepatic secretions ; there being two peculiar principles in the former, one chylopoiene, which can be isolated, the other, mingling with the bile, forms a third liquid, (intestinal juice,) which completes the digestion of the azotized substances. All kinds of food are reduced under the action of the different fluids concerned in digestion to three classes, viz : 1st Class, Albuminose. 2d Class, Glucose. 3d Class, Fatty matter. The albuminose class is absorbed by the veins and are poured into the general circulation and assimilated. The glucose is ab- sorbed by the veins which empty into the vena porta, and traverse the tissue of the liver. The third class, or fatty matters, having been dissolved by the pancreatic fluid, are absorbed by the lac- teals, and constitute the chyle, which probably undergoes a further change in traversing the mesenteric ganglions ; it is constantly al- kaline. Besides the element already mentioned, chyle contains lymph held in suspension, which has been erroneously supposed by some to be vegetable chyle. It is owing to the presence of lymph that chyle coagulates. After passing through the mesenteric glands, it assumes a rosy hue, which is owing, according to some physiologists, to the admixture of blood. Teedeman attributed this color to the lymphatics of the spleen. These discoveries are, I think, calculated to shed light upon certain forms of indigestion, whose seat has heretofore been placed in the stomach ; and we may be induced to search elsewhere for those de- rangements of the functions of digestion placed under the omnium ga- therum head of dyspepsia. A better plan of treatment may be adopted — a more appropriate diet, one which may leave the suffering organ in a greater state of repose ; thus, there have been cases of dyspepsia reported, which have been cured by confining the patient to a diet of fat bacon, which was supposed by most persons to be peculiarly indi- gestible ; here was a mystery which was explained by saying that, what was one man's food was another's poison. Would it not have been more philosophical to say that such a diet did not tax the sto- mach ; that organ being left in a state of repose, nature was enabled to repair the injury induced by the imprudence of the patient; the pancreas in the mean time furnishing the digestive agent? Again: when the stomach is the seat of any chronic disease, do we not re- commend a farinaceous diet, because experience has taught us that these articles of food are of easier digestion? I think that now a better reason can be given, when we know that the stomach is not called upon to aid in digesting them, but that this process is carried on in the duodenum. 254 CLAIBORNE ON ARSENICAL TESTS. We find also in certain forms of dyspepesia, that solid food is the most appropriate diet ; now, bearing in mind the functions of the sto- mach, whose office it is to digest the azotized class of aliments, should we not be led to ascribe the dyspepsia to a derangement of some other organ concerned in digestion ; for assuredly, if the stomach was the seat of disease, it would be somewhat paradoxical if it digested well that class of food for which all agree it is principally designed, and that class in the digestion of which it is only remotely or not at all concerned should be rejected. Would it not be more reasonable to refer the seat of disease to those organs whose especial office it is to digest the amylaceous class of substances, and that therefore, this kind of food was rejected, and that the stomach being free from disease, digested as usual the nitrogenized matter, for which it is peculiarly fitted ? Arsenical Testing. BY JOHN HERBERT CLAIBORNE, M. D., PETERSBURG, VA. The color and tastelessness of arsenic, the readiness with which It may be obtained, and, above all, its uncompromising and impla- cable enmity to life, mark it as an agent peculiarly fitted 1o meet all occasions upon which it is desired insidiously and criminally to bring about death. In the annals of crime and turpitude, its deeds are recorded as many, sure and murderous ; while to the wavering mind of the unhappy suicidist, it has appeared as kindly as Cato's sword— his bane and antidote. From these features it is invested with especial interest to the jurist and physician, as upon them may devolve the task of relieving the wretched being writhing in the agony of its cruel torture, or of dragging to deserved punishment the dastardly fiend who faithlessly places it to his neighbor's lips. Its modes of test and detection are oftenest committed to the physician ; and to qualify himself for the weighty responsibilities of this impor- tant office is befitting his most active care. In a late case, reported in the Philadelphia Medical Examiner for March 1851, a slight inaccu- rac}'', or a want of minuter research upon the part of the medical tes- timony, has delivered from the condign reward of his deeds, a wretch whom the clearest circumstantial evidence had convicted of murder, and returned to society a villain and an assassin. In view of this case, and in recently experimenting in arsenical tests, and reviewing some of those proposed and commended by the most emi- nent toxicologists, we have determined to publish the very accurate and conclusive methods devised for the detection of the poison — less, indeed, with the hope of presenting any newT or original experiment, than with the desire of awakening the minds of the profession in Vir- ginia to a subject which, though so important, has, in very many cases, we believe, laid long unnoticed. The form in which this substance is usually administered, crimi- nally as well as medicinally, is in that of the oxide of the metal ar- CLAIBORNE ON ARSENICAL TESTS. 255 senic, termed arsenions acid, commonly called by the uninitiated rats- bane— sometimes fly powder, and occasionally, very improperly, cobalt. It is a transparent, vitreous mass when first sublimed ,• but, as seen in the shops, is a white powder, tasteless, inodorous, except when heated, assuming then the smell of garlic, and very sparingly soluble in cold water. If in a case of suspected poisoning a portion of stuff of this cha- racter be found, under suspicious and unexplained circumstances, make a solution by throwing some of it into pure, (better distilled) hot water, and if it be arsenic, the following tests will easily prove it : Ammonio-nitrate of silver, prepared by making a strong solution of nitrate of silver, and carefully dropping into it aqua ammonia, till the precipitate falling is nearly re-dissolved, will throw down from the suspected solution, if arsenic be present in it, a yellow precipitate, arsenite of silver. An excess of ammonia will instantly re-dissolve this and give a clear solution ; hence the care necessary in preparing the ammonio-nitrate. Ammonio-sulphate of copper, prepared similarly and with like care, will throw down from another portion of the suspected solution, if arsenic be present, a green precipitate, arsenite of copper — a com- mon pigment known as Scheele's green. Hydro-sulphuric acid gas, bubbled through a third portion, will, if arsenic be present, throw down a yellow precipitate, orpiment — ses- quisulphuret of arsenic. If the supposed arsenic have been dis- solved in pure water, the evidence of these tests may be deemed con- clusive. But it is in very many instances impossible to obtain so pure a solu- tion of the suspected substance. We are often considered fortunate to obtain it even in the form of discharges from the stomach and bowels; and when mixed there, with a variety of organic material — vegetable and animal. The presence of these matters will variously interfere with, change the color of, or prevent the precipitates that should be thrown down by the two former tests, while the presence of any free alkali will prevent the formation of the yellow precipitate by the hydro- sulphuric acid. The organic matters, before experimenting, must be gotten rid of, and the following process of doing this is simple and effectual : Boil the suspected matter for an hour in distilled water, then filter, and set the liquid aside to cool. This will, to a great extent, remove all organic material. If it should not, the addition of a small portion of acetic acid will give a ftocculent precipitate, and the mixture must be still further purified by adding to it a strong so- lution of the oxide of zinc in potassa. The oxide will unite with and carry down all of the remaining organic matter, and the potassa will remain in solution in the form of an arsenite. Now filter — neutralise a part of the liquid by the addition of an alkali or acid, as the test paper shall indicate necessary — and proceed to test with the ammonio- nitrate of silver and copper, as in the last case. The ammonio-sul- phate of copper will throw down a green precipitate., if arsenic be present in the proportion of one to five thousand parts of the liquid — the ammonio-nitrate of silver, a yellow precipitate, if arsenic be pre- 256 CLAIBORNE ON ARSENICAL TESTS. sent in proportion of one to four hundred thousand parts of the liquid. Take a third portion of the suspected fluid and bubble through it hydro-sulphuric acid gas — having first, however, acidulated this por- tion, as the expected precipitate, the sulphuret of arsenic is highly soluble in any free alkali. If arsenic be present to the two hundred thousandth degree, a yellow precipitate will fall. But the sulphurets of antimony, tin, cadmium and selenium are also yellow, and if either of these metals be present in solution will likewise be precipitated. Hence it becomes necessary to examine this precipitate more mi- nutely. Obtain it by filtering — -carefully dry, and place it down to the bottom of a clean glass tube hermetically sealed at one end — throw down upon it twice its weight of powdered charcoal and car- bonate of soda — -wipe the glass out carefully down to the mixture by a piece of cotton on the end of a wire, and heat the closed end in the flame of a spirit lamp. The carbon will abstract the oxygen from the minerals, arsenic and soda, and carbonic acid will escape — the sulphuret of sodium will be formed and metallic arsenic be sublimed, depositing a dark ring upon the tube where it is condensed a short way above the materials heated. But antimony treated in a similar manner will also give a dark metallic ring — and how shall this be known from arsenic ? Cut off the tube below the ring, incline it and heat the lower end so that a current of atmospheric air may pass through it. The metallic arsenic will be oxidised, arsenious acid will be formed and seen depositing in white crystals above the ring. This may be taken, washed out into a tumbler of distilled water, and easily tested as a pure solution of arsenic. This experiment may be condsidered conclusive. But it sometimes happens that none of the ejectments from the stomach or bowels can be obtained. In the absence of suspicion, these are usually thrown away, and when the question comes up for medico-legal investigation, the body of the deceased is all that re- mains, or even this may have been buried for weeks or months. If, however, the stomach or bowels can be procured, the presence of arsenic, may even now be detected, if it exist, only requiring minuter investigation for its detection than in the former cases. Let the procured matter be weighed, whatever it be — perhaps a part of the stomach — add to it one-sixth of its weight of sulphuric acid, and digest for a day or two. The organic matter will be trans- formed by the action of the acid into carbonic acid and water, and a char will remain as a sediment. Now add to this one-sixth of its weight of nitric acid and the char will be consumed and a clear solu- tion be left. The fluid is now ready for the test ; and to determine whe- ther arsenic be present, we will resort in this case to the plan de- vised by Marsh, upon the principles of the powerful affinity of hydro- gen for arsenic. He has constructed an instrument especially for the purpose, but it is not always readily obtained, and the experiment can be as well conducted without it. The only object is to cause hy- drogen gas to be generated within the suspected liquid, and the most convenient manner in which this can be done will prove the test. Let us place the liquid to be tested in an ordinal glass retort — add CLAIBORNE ON ARSENICAL TESTS. 257 to it a little sulphuric acid and throw in some pieces of zinc — hydro- gen gas will be immediately generated by the action of the acid on the metal, and in its nascent state will seize upon the slightest portion of arsenic present. The gas which then escapes will be arsenieu- retted hydrogen. Permit this to escape until there shall cease to be any admixture of atmospheric air, to avoid the accident of explosion, which would necessarily ensue upon firing the mixed gases, and then apply a taper. Hold over the burning gas a cold, polished surface, as of a piece of porcelain or glass, and the sublimed arsenic will be condensed in a dark, metallic spot ; or we may cause the gas to pass through a small glass tube, and without firing it, heat the tube through which it passes. Hydrogen will be driven off and a black, metallic ring, arsenic, be deposited. This process will detect the presence of arsenic to the five hundred thousandth degree. It will reveal the existence of one hundredth of a grain in a pound of sto- mach. (Prof. R. E. Rogers.) This experiment might be considered as perfected at this stage of the process — but for the fact that hydro- gen will form with both antimony and mercury compounds, which, burning, will each give the characteristic dark ring. And may not the unfortunate victim of crime possibly have taken calomel or tartar emetic in his last illness, and thus introduced mercury and antimony into his system as well as arsenic ? And would not this possibility materially affect the legal consequences of the medical testimony, if not. the truth of the case? In a criminal case tried some years since in New York city, a me- dical man, summoned as a witness, swore, upon the strength of this experiment of Marsh's, that he could tell the shadow of a shade of arsenic without doubt or deception ; and pointed to the black, metallic ring to sustain him. But a shrewd lawyer, in minute research, prompted by a lawyer's characteristic regard for justice and love of the whole truth, discovered that mercury similarly treated with hydrogen as ar- senic would give a similar dark ring ; and therefore our medical friend proved too swift a witness. The experiment, however, may be made perfect. If heat be applied to the metallic spot or the metallic ring, and it be arsenic, it will be volatilized and disappear, because the point of volatilization in arsenic is below its point of fusion. On the contrary, if the metal be mercury or antimony, it will melt and run into globules. Or the tube may be cut off, containing the ring, in- clined and heated so as to cause a current of air to pass over the ring, when, if it be arsenic, white crystaline arsenious acid will be formed, which may then be tested by being thrown into solution and acted on by ammonio-nitrate of silver, ammonio-sulphate of copper, and sul- phuretted hydrogen. Or it may be thrown into a test tube with flux and be re-sublimed, which will cap the climax of perfective experi- ment. Great care is necessary, however, in the choice of the mate- rials to be used in experimenting. The common sulphuric acid of commerce, and more especially the zinc, sometimes contain arsenic in sufficiently great proportion to respond to these delicate tests ; and hence, if not known to be perfectly pure, they both should be tested be- fore being used in an experiment where life or death may be concerned. 30 258 CLAIBORNE ON ARSENICAL TESTS. The glass of the tubes, in which the suspected materials may be placed previous to being treated with black flux, may also readily de- ceive the experimenter by giving, when heated in the spirit lamps, a ring of metallic lead, the oxide of which they contain. These might also be tested. The French manufacture tubes of pure leadless glass, (silicate of soda,) especially for the purpose of being used in this deli- cate testing, and these, if procurable, are greatly to be preferred. Lais- saigne proposes the following plan of separating the arsenic from the hydrogen, when the arsenieurreted hydrogen gas has been obtained. Pass the gas through a solution of the nitrate of the oxide of silver, the hydrogen will seize upon the oxygen of the oxide, metallic silver will be precipitated, and nitric and arsenious acids will be left in solution. Add a little muriatic acid to precipitate any silver that may be in ex- cess— filter and evaporate the solution. Arsenious will have become arsenic acid by absorption of oxygen from the nitric, but it will be left on the filter, and may then be treated with the usual tests. Dr. Christison commends a plan devised by Professor Reinsch. He throws into the suspected fluids muriatic acid and copper. If arsenious acid be present, it will give up its oxygen to the copper ; the muriate of the oxide of copper will be formed, and the arsenic will appear in a steel grey deposit upon this. As antimony, bismuth, tin and zinc, if present, might also give a deposit upon the copper similar to arsenic, and only differing a little in color, it is necessary that this should be sublimed from the copper, and the usual tests exhibited. The ease and accuracy with which these experiments may be con- ducted, afford to the physician and jurist an efficient and gratifying means of basing their decisions upon the truth ; while the certaint}r which must attend their results ensures to the accused the benefit of that justice which the law metes out. In a case in which life and death are concerned, probably no strength or clearness of circumstantial evidence should render unne- cessary the eliciting of the metallic ring; and if one link be wanting in the chain, or the slightest doubt of the guilt of the prisoner pervade the mind of the jury, the evidence of the minutest chemical investiga- tion should be required. It may not be amiss to state in conclusion, that the antidote of ar- senic, the hydrated sesquioxide of iron, which is not always readily ob- tained, may be crudely prepared in a few minutes by adding a satu- rated solution of carbonate of soda to the muriated tincture of iron, (Rogers,) until effervescence ceases. The mixture, containing nothing but the muriate of soda or common salt in solution, and the hydrated sesquioxide of iron in sediment, may be administered by the wine- glassful. It is harmless in itself, and if arsenic be in the stomach or bowels, will form with this the insoluble and inert arsenite of iron, and consequently prevent its further pernicious action. This may then be caused to be ejected by cathartics and emetics ; and the in- flammatory or other symptoms of the previous action of the poison be treated on general principles. GARDEN ON TURPETH MINERAL IN SCARLATINA. 259 On Turpeth Mineral in Scarlatina. BY T. J. GARDEN, OF WYLLIESBURG, CHARLOTTE, VA. I noticed in the February No. of the Stethoscope, that Professor Met- tauer of Randolph Macon, in his paper on scarlatina, has made an apt and appropriate allusion to a vaunted specific, " Turpeth mineral," used within the last 20 years as a secret remedy by a physician and graduate of Virginia, in this formidable disease. As it has always been our aim to find out the truth, and to make it known, we deem it a fit and suitable occasion to re-publish, in a respectable medical journal, some interrogatories published by us in the Enquirer about the time referred to by the professor, with a view, if possible, to elicit the whole truth in relation to this mooted subject. A reply now, through the columns of a medical journal, will enable the professional public to decide upon its merits. Should that verdict be in its favor, the disease will at once find a local habitation and a name, and be shorn of its terrors everywhere. A reply was promised us at that time through the columns of the Philadelphia Journal, (Hays',) but it has not as yet, to our disappointment and regret, seen the light. One thing is certain, there is truth in it, or the unprofessional public, by a strange delusion, were at one time made to believe a lie. Here follow the interrogatories : 1st. Dr. *****, near Finneywood, Charlotte, is likewise solicited to give his views of the modus operandi of his remedy as they present themselves to his mind, and to point out its superiority over other modes of treatment, as it is apprehended the mode he has adopted for giving publicity to it, will limit rather than enlarge the sphere of its usefulness ? 2d. Whether the peculiar article employed b}' him produces, in ad- dition to its more obvious operative effect, any specific impression upon, and change of condition in the diseased structure, whereby such a counteracting and resolved power is exerted over the disease as to supersede in its subsequent stages, in all cases, a resort to other efficient modes of medication? 3d. Does he not believe he has had, in the general, a mild disease to treat, (for there are grades of it from the mildest to the most ma- lignant, the former of which the physician need not tamper with, and the latter he most assuredly cannot cure,) and that his remedy has been resorted to in a very large proportion of mild cases ; and, is it not fair to infer, that it has obtained the credit of the cure very often in cases which were so very mild as would have resulted favorably if left to nature ? 4th. Is he prepared to maintain, from multiplied observations and very considerable experience, from many trials, and from the obser- vations of many under the direction of other physicians, by careful comparative observation of this with other methods at the same time and place, and in the same epidemic, and much more a thorough trial of this with others by the same practitioner, that his method is superior to all others ? 260 GARDEN ON TURPETH MINERAL IN SCARLATINA. 5th. While it is admitted to be an undoubted fact that the fatal cases will unquestionably be found to be less numerous in this, as in all acute diseases, under some plans of treatment than under others, should the advocates of this exclusive method not beware of doing such injustice to themselves as to make any pretensions to its curing all cases, or that it is to be " relied upon with as much certainty as mercury in syphilis ;" for is it not equally certain that a certain pro- portion of all acute diseases, under ordinary circumstances, will al- ways be found incurable ; and that, too, under any and every method of management? 6th. Whether by his mode of treatment the patient is relieved from the dangers of a terrible factitious disease, and is in no danger of be- ing subjected to subsequent exhaustion or excessive morbid irritabi- lity, and the necessity of struggling both against exhaustion and a violent factitious malady, oftentimes the worse disease of the two ? If an affirmative answer can be given to this last interrogatory, and clearly sustained, herein, I imagine, will be found to reside the virtues of the doctor's specific in scarlet fever ; for, although the dis- ease may be inflammatory, I maintain that this state or condition is not always the same, and that tartar emetic and the lancet are not al- ways the safest and surest means of subduing it. Evidences to this fact are not wanting from numerous sources, and may be obtained from almost daily observation. I consider the lancet in this disease as a " sword put into the hands of a fool, " an agent of destruction and devastation, rather than an auxiliary in the treatment. I design to condemn its abuse, not its use. No argument with me, however, " like matter of fact, " is in a science which does not rest upon ab- stract reasoning alone, than which nothing has contributed more to retard its progress, or lead its votaries so wide from the truth. The foregoing enquiries are submitted in the true spirit of science. Truth, humanity itself, and the honor of the profession demand they should be met in the same spirit. The interest we feel in this matter, too, has suffered no abatement from the fact that another physician and graduate of Virginia, who, to our face, at one time, was clamorous in his denunciations of the doc- tor and his specific, was afterwards seen writing and publishing his praises of its virtues and powers in this very disease in a Western journal ; so that his opinions, when seen in private and exhibited in public, appeared in opposite shades of light and color. If my me- mory serves me right, that writer stated he had seen it used success- fully in one hundred cases, without witnessing a solitary fatal result. Wonderful success ! He stated that the specific action of the mineral on the system was speedily developed, and in this way he accounted for its success. Turpeth mineral is a violent emetic, and if not skil- fully wielded, would inflict direct injury. We all know how credulous persons are who are the victims of disease in regard to secret nostrums, and that a man of intelligence, who will scruple to confide his health to the care of such physicians, as should be the just objects of his confidence, will venture to take, through an unaccountable infatua- tion, the most dangerous medicine, upon the credit of an imposing ad- GARDEN ON TURPETH MINERAL IN SCARLATINA. 261 vertisement. In charity we are willing to award to the author of this pretended specific a tact in the use of it which few can claim. This is true of most remedies, and applies to all physicians — not that the individual is a man of superior skill either, but has a greater tact in the use of some particular remedy, and is thereby enabled to produce effects which none other can. For the information of such as may feel inclined to give this remedy further trial and more extended ob- servation, we will just state that the mode of using it, as taught and practised at that day, is simple enough. The mineral is blended with a few grains of ipecacuanha and simply rubbed upon the tongue until the tongue is lightly coated. The patient, if a child, is made to suck a bit of sugar, which washes down the mineral and ipecacuanha. Vomit- ing speedily ensues. If an adult, the mineral and ipecacuanha are blended in relative proportions with a little hot water in a spoon. If its action prove too violent, either by emesis or catharsis, it is checked by a little laudanum or paregoric. The balance of the treatment con- sisted in diluent drinks, and teaspoonful doses of castor oil to keep the bowels free, with an occasional sinapism to the epigastrium. Seven- teen years ago, when scarlet fever was endemic in our vicinity, a great deal was said on the subject of the success of this remedy. This perhaps was all cabaling. We do not assert that it was so, but per- haps it was so — we were in the habit ourselves of making compara- tive observations with other modes of treatment. In one family, the only fatal case was treated with the mercurial emetic. In this case, the child was vomited in half an hour after the disease developed it- self. It was a family of rank and fortune, and as we were required to spend a great part of the day, and five successive nights with the family, no time was lost in its administration. I recollect at that time we were inclined to attribute the secret of the success of this remedy more to the non-jierturbatmg treatment afterwards, than to any specific action of the agent employed. It was a form of scarlatina in which more was done by not doing, than by doing at least in a large propor- tion of the cases. Until physicians are more successful and less divided on the mode of treating this disease, further facts and observations from any quar- ter will need neither preface nor apology ; for it is only by a faithful narration of its pathological anatomy, and the effects produced on it by remedial agents, whenever it has been epidemic in the same and in different places, that its treatment can ever be correctly ascertained. Some may think the general stock of information already possessed on this subject sufficient. Experience has long since proved that the same remedies produce very different effects in the same disease, at different times and in different epidemics. Stimulants, emetics, ca- thartics, mildness and harshness, are only relative terms. We have seen tartar emetic purge and calomel puke, and stimulants impart no strength; and within the last thirty years we have seen small doses of castor oil operate as a hydrogogue cathartic, and kill the patient. In the same state of the system we have seen spts. terebinth., the mild- est of all purgatives. 262 young on placenta previa. A few Observations on Placenta Frsevia. BY THOS. J. YOUNG, M. D., OF PRINCE GEORGE COUNTY, VA. It is not my intention, in considering this subject, to enter into a de- tailed or very elaborate account of the causes, symptoms, and vari- ous methods of treating this most appalling condition : (for all these I find to have been sufficiently, and very ably animadverted on in the January Number of the Stethoscope.) It is my purpose only to offer a few concise and common-place remarks, in condemnation of a plan of treatment now in vogue with some, and which I find discussed at some length in the article above referred to, viz : with the tampon. Not that I wish to detract anything from the merits of the tampon as a remedy in treating uterine haemorrhages generally : nay, for within itself, when judiciously and timely applied, we have a blessing for the mother, when all other means have failed to afford her relief. But as the mother is not the only one to whose welfare the physician in the practice of his obstetrical vocation is called upon to look, it be- hooves him to discriminate nicely the cases for its application, lest it prove in his hands a curse, in lieu of a blessing. Would any accou- cheur think of introducing a tampon into the vagina, so long as a hope of saving both parent and offspring existed, or until the sacri- fice of the child was called for to warrant the security of the mother? Surely not. Then, if he thinks not of this, why should he advise its introduction in placenta praevia when the os uteri is neither dilated or dilatable ? Does he expect by this means to plug the orifices of the bleeding vessels, and thus remedy the evil? If this he could do, by bringing the tampon into immediate contact with the gaping vessels from which the blood is issuing, it would be indeed a happy resort ; but when we take into consideration the relative position of the vagina and uterus, and the undilalable state of the os uteri, we see at once the utter impossibility of such contact, and are led to the con- clusion that the tampon, by confining the blood, and damming it back upon the uterus, converts the previously open, into a concealed haemor- rhage, and thus enhances the danger tenfold. The blood will con- tinue to flow with every renewed contraction of the womb, and hav- ing no outlet through which it can pass, will necessarily collect in the remaining portion of the cervix uteri, and between the superfices of the womb and placenta, dissecting the latter body entirely from its seat on the matrix — and in this manner effectually shutting off the natural supply of oxygen from the foetus, the result of which is evi- dent to the merest tyro in medicine. This is the first objection to its use that should present itself to the mind of every discriminating accoucheur, and is within itself of sufficient magnitude to deter him, and stay his hand whilst yet it is not too late. A second objection to its use, is this : The capacity of the womb, from the fifth month of utero-gestation until the completion of term, is such that it is capable of containing blood enough to endanger the life of the female, notwithstanding the vagina may be securely tamponed. walke's case of hydrocephalus. 263 There is yet a third objection, although of less importance than the two preceding, yet it is of sufficient weight to demand our attention. It is this fact, (which has long been familiar to the profession at large,) that the presence of a coagulum of blood in the vagina and uterus so depresses the nervous system of the parturient female, that she will die of exhaustion, (if not relieved by breaking up and turning out the clot,) long before the loss of blood is sufficient to produce such a de- plorable catastrophe. Let me add, in conclusion, that I renounce the practice as hazardous in the extreme ; and I consider it a duty incum- bent on my professional brethren to view it in all its bearings before putting it to the test. Let them consider well the dangers of convert- ing this open into a concealed haemorrhage, which I have endeavored to show is : first, The certain loss of the child by asphyxia ; second- ly, the capacity of the womb being such as to make it a questionable remedy ; and thirdly, the extreme nervous depression caused by the presence of a coagulum of blood in the uterine cavity. Let them, instead of experimenting rashly with their patients, look calmly and re- flectingly to the exigencies of the case, and model their treatment ac- cordingly. I much wish that time would permit me to lengthen out this essay, and discuss at some length a different and a much safer plan of treatment; but as I have neither the time nor the inclination to be prolix, I will draw my remarks to a close, hoping at some future time to be enabled to do the subject more justice. Hydrocephalus. March 1851. Dear Doctor : As I prefer this mode of communicating a case I re- cently met with, I send you the report of a case of hydrocephalus supervening upon the sudden disappearance of an eruption of integu- ments of the cranium, with profuse serous discharge — a fatal termi- nation. W. W. B., infant child, aged five or six months, was troubled from very early infancy with a spontaneous scaly eruption of the species pityriasis capitis of Willan. This eruption, as I learn from the parents of the child, first presented itself in an isolated form, but soon began to spread uniformly over the head, until the entire scalp was involved. Unlike scurfiness, as described by authors, there was always more or less redness, indicating an inflamed condition of the parts, only to the extent, however, of maintaining, as I supposed, a natural process which nature had adopted, whereby the system might be freed of some vitiation by a serous discharge, which was quite profuse up to within ten clays of the child's death. This state of things continuing, and seeming to bid defiance to the many little sooth- ing applications made by an anxious mother, induced the parents to consult me in regard to the propriety of " drying it up," (to use their own expression,) which I positively admonished them against, having been informed that the child enjoyed uninterrupted general health, and perceiving, as I supposed, a hydrocephalic diathesis. Unfortu- nately for the child, the mother, (as they usually do,) considering the 264 walke's case of hydrocephalus. personal appearance of primary importance, and not appreciating the principles upon which rny advice was founded, employed poultices of various kinds, with a view of relieving the inflamed scalp and thereby relieve the child of the excessive itching with which it was troubled. After the application of some three or four poultices, there was an apparent amendment in the local affection, which continued rapidly to disappear, until there was not a trace of lesion to be seen of the former eruption. About this juncture the parents discovered the child somewhat in- disposed, which, continuing for several days, induced them to send for me. Feeling more than an ordinary interest in this little child, I was quite surprised, and at the same time uneasy, at finding the head en- tirely relieved of what I conceived, from the first, to be an issue set up by nature for the purpose of relieving the system of some vitia- tion, or as the ancients supposed, "peccant humors." Though there were no physical symptoms prognosticating the existence of effusion when I first saw the child, still, when I was informed that the child, naturally lively, had been disposed to be drowsy and fretful for seve- ral days, I had my fears excited in relation to what might be the ulti- mate issue of the case. I must confess, that had I not known the cir- cumstances under which the symptoms, drowsiness, fretfulness, &c. were ushered in, I would not, at so early a stage of the effusion, have pronounced it emphatically hydrocephalus. My suspicions were only aroused, knowing that an issue discharging a vast quantity of sero-jm- rulent matter had been repelled, during the existence of which the child enjoyed perfectly good health. These facts, linked with the symptoms, drowsiness, a fretful disposition, &c, warranted me, as I thought, in suspecting more or less effusion about the brain. After prescribing such remedies as I thought the symptoms indi- cated, I left the child to see it the next day. On my next visit I was very much disposed to believe the child better, finding the s}7mptoms not so threatning, and, as I thought, a general improvement in every way. The next morning, however, I was summoned, at an early hour, with the melancholy tidings that the child was worse, and on my arrival found all the symptoms greatly aggravated. The case now evidently presented symptoms which I could not mistake for any other than those of incipient hydrocephalus. These alarming symptoms gradually increased day after day, with dilated pupils — the eyes remaining nearly all the time open and intently gazing, with- out expression, at some stationary object. In a short time spasms super- vened, at irregular intervals, lasting from a few minutes to an hour and a half, the little creature apparently suffering the greatest agony, evinced by loud and unnatural shrieks, distortion of the frame, &c. This state of things continued for forty-eight hours, more or less, when the child expired. It would be proper to state that the pulse throughout the attack presented no peculiarity — there being very little excitement, and it was generally soft and yielding, contra-indicating the presence of inflammation. Remarks. — This is a very interesting case, in a pathological point of view, and tends to elucidate somewhat the difficulties, acknowledged WALKE S CASE OF HYDROCEPHALUS. 265 by authors to exist, in discriminating between hydrocephalus as a disease, or merely a symptom of disease. There is great contrariety of opinion with authors in regard to this disease — some believing it to be unlike the other hydropic diseases dependant upon the develop- ment of a peculiar diathesis, but rather the result, of some pre-existing inflammation or irritation — thus making it merely a symptom of in- flammation or irritation of the brain, or its meninges. Bell and Stokes say, " The old idea of this affection was, that it was a species of dropsy, depending on the relaxed state of the cerebral vessels, and hence the term hydrocephalus. Modern pathology has shewn that the occur- rence of serous effusion is a mere accidental circumstance, as it is pre- sent in one case of arachnitis and absent in another. When it does occur, however, it is the result of inflammatory disease, and it is to the prevention and cure of this that the practitioner must direct his atten- tion." This I conceive to be very bold language in the face of the strongest evidence in support of hydrocephalus, sometimes originating in its own peculiar way, and in direct opposition to the experience of many authors enjoying equal celebrity. Dickson confesses his embarrassment in defining the disease patho- logically, but dissents from the doctrine preached by the authors quoted above. He adduces good authority, and also relates many cases as occurring in his own practice, supporting the doctrine. of me- tastasis of serous effusion. Wood says — " It is possible that the same condition of the blood and of the extreme vessels, which sometimes induces dropsy in the cellular tissue and the serous cavities, may operate in the brain so as to occasion hydrocephalus, especially when, from a want of union be- tween the bones of the cranium, little resistance is offered to the ac- cumulation." Underwood also speaks of scirrhus tumors, a watery state of the blood and debility as sometimes occasioning the disease in question. I might adduce (were it not for taking up too much room in your valu- able journal) many more authors to substantiate the opinions main- tained by those already mentioned. The authority last quoted, as corroborative evidence with my own experience, (however limited,) forces me to support the latter doctrine, and to believe that hydroce- phalus may exist independent of previous inflammation. That cases of hydrocephalus do sometimes occur as the sequelae of arachnitis I readily admit, but to suppose that, every case of dropsy of the brain is necessarily dependent on a pre-existing inflammation of the tissues of the brain is, to me, preposterous. Dr. Rush, in speaking of dropsy of the brain being sometimes occasioned by the exanthe- ma, says, " I have seen one case of dropsy of the brain, in which it was obviously the effects of debility induced upon the system by the measles." There is such a thing, we know, as congenital dropsy of the brain, evinced by an unnaturally large head, together with fluctuation on percussion ; and this state of things has existed for months and years, and the child ultimately recovered without the slightestest appearance of inflammation of the brain or its mem- branes, or even functional derangement of this important organ, 266 walke's case of hydrocephalus. which latter phenomenon, we know, is an almost invariable attendant upon inflammation or irritation of the brain. I have seen a case in which the head was swelled to an incredible size, and, as I was in- formed, had gradually increased in size from birth, to the extent of rendering the child (now three' or four years old,) unable to elevate the head erect on the vertebral column — the head, obeying the laws of gravity, would fall in any and every direction, the child seeming to have no control whatever over it ; and, notwithstanding, so far from phrenitis or arachnitis accompanying these extraordinary phe- nomena, the child enjoyed perfect health ; its appetite was uniformly good, and, what was astounding, was noted for its sprightliness of mind. As my purpose is of a twofold character — first, to adduce the case described above to substantiate the doctrine that dropsy of the brain does sometimes occur, independent of antecedent inflam- mation of the brain or its meninges — and secondly, to remonstrate against an endeavor to repel eruptions of a similar character, know- ing it to be the practice with some to use various unguents, with a view of affording speedy relief — after having briefly noticed the rea- sons that induce me to yield to the theory of metastatic influences, producing the disease in many instances, I propose noticing some principles that should ever direct us when we are called on to pre- scribe in a case similar to the one reported — indeed, in treating any spontaneous issue set up by nature in her sovereignty, for wise pur- poses, though not appreciated by us. When we reflect on the many ways nature has to accomplish her ends, when her fair fabric is as- sailed, and the success usually attendant upon her efforts, when un- fettered and displayed in her own favorite way — I say, we should pause and survey the ground well before we adopt any measure, even adjuvant to her own means, much less those at war with every prin- ciple, and inconsistent with the very nature of the case. Let us take a few cases for example, illustrative of the wonderful feats of nature. How frequently, after spending anxious days and nights, in a case of fever, after all our means have been fruitlessly exhausted, and the monster, disease, as it were, seems to reign " monarch of all he sur- veyed," a floodgate, somewhere or other, is opened, and the pent up and vitiated secretions, which were working disorganization and death, are permitted freely to escape, and the "vis mcdicatrix naturae" to collect its scattered forces. Hence the critical sweats ; critical haemorrhage; critical diarrhoea; the copious expectoration, and uri- nary discharge, which we hail with so much pleasure — to stop or sus- pend which, would almost certainly ensure the death of the indi- vidual. Might we not apply the same reasoning to other morbid conditions of system besides fevers, and reasonably conclude that, for every ab- normal state of the economy, there is some process by which nature endeavors to administer relief? I should say we might. The same might be said of eruptions almost of every description. There is some internal disorder which they are intended to modify or cor- rect— hence the fatality attendant upon the exanthematous diseases, because of a too frequent interference with, and blocking up, the way Johnson's case of resection of femur. 267 marked out by nature for her own footsteps. Modern writers are more negligent, I think, than the ancient, in impressing the importance of duly considering the designs of nature in establishing issues and critical discharges of every description. That physician who con- forms more nearly, in the treatment of disease, to the modes usually practised by nature, will have his efforts more frequently crowned with success, and deserves more richly the encomiums which should be heaped upon the medical man of science. No one, I ima- gine, after reading the history of this case, would question that the sudden disappearance of the eruption, and the serous discharge con- sequent thereon, was the " causa proximo" of the effusion upon the brain, which resulted in the death of the child. Nothing, we know, is more common than for us, in indeavoring to remove a disease safely located, to transplant it to some vital organ. In such a case, the primary disease either assumes its original type, or puts on an en- tirely new garb. Remedies are sometimes prescribed in the eruptive diseases of the integuments of the scalp and face, peculiar to children, with no view to their specific action in relieving or repelling the erup- tion ; but such remedies, while they do not thus act, may occasionally combat successfully the excitement or irritation upon which such erup- tions or discharges depend. I do not, therefore, always see the ne- cessity of interfering with such diseases, (beyond cleanliness,) when we see the child enjoying good general health. We should also bear in mind, that these diseases are most frequently met with in children of robust and vigorous constitutions, and generally in a few weeks, or months, at least in due time, the affection disappears, leaving the child in the enjoyment of permanent health. With the hope, dear sir, that you may have your most sanguine expectations realized in the laudable enterprise you are engaged in, and that the profession, particularly in the South, may feel it their du- ty as well as privilege, to contribute to the efforts of the first indi- vidual (that we know of) who attempts to edit a medical journal in this state, I subscribe myself, Most respectfully, yours, J. WISTAR WALKE, Clover Hill Coal Mines, Chesterfield County, Va* Dr. P. Cl. Gooch, Editor of the Stethoscope. Case of Re-section of the Ununited Ends of a Fractured Femur. BY CARTER P. JOHNSON, M. D., Professor Anatomy and Physiology Medical Department Hampden Sydney College. The subject of this operation was brought before the class in the operating room of the medical college, on Saturday, November 30th» and the following statement made in reference to the case: 26S Johnson's case of resection of femur. P. F., an Irishman, about 19 years of age, of robust frane, in sound and vigorous health, was brought into the wards of the infirmary on the 20th August, having just suffered fracture of the right thigh by the falling of a derrick connected with the gas-works then in process of erection in this city. Upon examination, the fracture was found to be very oblique from behind, forwards and from above, downwards, in the upper third of the bone ; the leg was consequent!}' much short- ened. ' As there was much swelling and pain about the seat of the injury, the limb was temporarily placed in a fracture-box and cold ap- plications made until the third day after the accident, when, the swelling having sufficiently subsided, the fragments were adjusted and the limb placed in Smith's fracture apparatus. Shortfy after the ap- plication of the apparatus, an important part of it broke, rendering it necessary to remove it altogether. The limb was then carefully ad- justed in Physic's modification of Desault's apparatus, which effectu- ally maintained the fractured fragments in apposition. During the night, the patient finding the extending bandage pressing uncomfort- ably upon the foot, removed it, and at the next visit the parts were found in precisely the same condition as before the application of the instrument. The apparatus was again carefully adjusted, great care being taken to protect the heel and instep from undue pressure. At night the patient again removed the bandages, and though continually warned of the consequences of his folly, continued to remove them for fourteen or fifteen days after their first application. Ultimately, by the use of Barton's handkerchief, in lieu of the ordinary bandage, the apparatus'was applied in such a way as to give him no pain. We have reason to believe, however, that by the aid of a fellow patient in the ward, who had observed the simple mode of applying the handker- chief, he continued to loosen the extending band every night, escaping detection by having it tightened again in the morning before the wards were visited by the dresser. At the expiration of eight weeks after the application of the appa- ratus, it was removed, and no evidence of union appeared. The leg was immediately retracted about two inches and a half, and the bro- ken segments of the thigh could be freely moved upon each other. There was no crepitus, shewing that the ends of the bone were co- vered, and that a false joint had been formed. There can be no doubt that this most unfavorable termination of the treatment of this frac- ture was caused bv the continual motion between the fractured ends of the bone whenever the bandages were removed by the patient during the period when callus was being thrown out, and when it was most important that perfect immobility of the parts should be pre- served. Such having been the result, the question occurs, whether the pa- tient should be subjected to any further treatment. If permitted to remain as he is, his limb will not only be entirely useless, but a posi- tive inconvenience to him. He is unwilling to submit to amputation, nor do we advise it. With the hope of producing union between the ends of fractured bones thus ununited, several modes have been pro- posed, viz: long continued rest, accompanied by pressure, friction of JOHNSON S CASE OF RESECTION OF FEMUR. the ends of the bone and the seton. None of these remedies, I appre- hend, are applicable, except in cases of transverse fracture, or where the obliquity is comparatively slight; and in the case now under con- sideration, where the ends of the bone so overlap as to be separated from each other at least three inches, could be of no avail. The only other remedy proposed worthy of consideration at this time, is that of resection of the ends of the bone and the co-aptation of the transverse surfaces thus exposed. This, where the bone involved is the femur, becomes a difficult and a hazardous operation. Do the statistics in reference to this operation justify its performance? Out of 150 cases of ununited fracture collected by Dr. Norris, the operation of resection was performed in 38. Of these, 24 were cured, 1 amended, 7 failed, and 6 died. Twelve of these cases were in the femur, of which 7 were cured, 2 failed and 3 died. Now, when it is recollected that one of the most common causes of non-union of fracture is some consti- tutional affection, such as syphilis or scrofula, which would operate as powerfully in preventing the success of the operation as in producing the non-union, it is fair to presume that some of the failures in the above-mentioned cases were attributable to that cause. Applying these statistics to the case before us, where there is not only no con- stitutional affection, but the individual is in strong and vigorous health, and at an age when the nutritive functions are fully and perfectly de- veloped, they would seem to justify and even to indicate the opera- tion. It is regarded, however, as a most serious and hazardous ope- ration, and has only been determined, upon at the request of the pa- tient, and after the whole of its danger has been fully explained to him. After these remarks to the class, and after explaining the successive steps proposed to be taken in the operation about to be performed, the patient was put fully under the influence of chloroform, and kept so by applications repeated whenever he appeared to be emerging from the anaesthetic state, during the whole operation.* The operation was then commenced by an incision extending from a point opposite the trochanter major to a point opposite the outer sur- face of the external condyle. This incision extended down to the fascia lata, which was then divided continuously with the first inci- sion. In order now to reach the lower end of the upper fragment of the fractured bone, which was drawn forwards and outwards, the vastus externus muscle was separated from its attachments to the rec- tus femoris and held back by an assistant. With some little difficulty the extremity sought for was found, a chain saw passed around it about an inch from its termination, the section readily made, and the fragment separated from its ligamentous attachments and removed. The next step in the proceeding, viz : the section of the upper ex- tremity of the lower fragment, proved very difficult in consequence of the great retraction of this portion of the fractured bone. This lower * This was one of the cases referred to by the Committee on Anaesthetic Agents, in their report published in the last No. of the Stethoscope, as having probably proved fatal in con- sequence of the use of chloroform. The sequel will shew, however, that there is no good ground for attributing the result to any other agency than the shock of a violent operation. 270 Johnson's case of resection of femur. fragment was found drawn up to the lower portion of the genital re- gion, and carried by the adducter muscles very considerably inwards, rendering its access by an external incision very difficult. Finding it impossible to reach the upper portion of this fragment through the separation already made between the vastus and the rectus, the vastus was then separated from its posterior attachments and turned forwards. After a very tedious dissection, in which the handle of the scalpel and the fingers were used very much to the exclusion of any cutting in- strument, in order to avoid the risk of dangerous haemorrhage, which was imminent, the extremity of the bone was at length reached, and with considerable difficult}', owing to its very great depth, the chain saw passed around it. This portion of the operation was much faci- litated by carrying the foot across the opposite instep, so as to force the fragment sought for nearer to the external surface of the thigh. The chain saw, bound down both in front and behind by the thick muscles and the strong fascia of the thigh, was worked with difficulty, and before the section was accomplished, broke. A good metacarpal saw which was at hand, however, made a very good substitute, and with it the section was finished. The separated fragment, about an inch and a half in length, was then easily removed. The two oppo- site ends of the bone, thus rendered transverse, could then be brought accurately into contact, producing a shortening of the limb of about two inches and a half. The next step in the operation consisted in boring, with a small bit and brace, a hole in each of the ends of the bone thus approximated, through which a very strong silk ligature was passed by means of an eye-probe, and firmly tied. The holes were bored obliquely, commencing each about half an inch from the sawn extremity, and passing the one upwards and the other downwards, and terminating in the medullary canal. The ends of the ligature were brought out of the wound. The edges of the wound were then brought together, the limb lightly bandaged, a long splint applied along the whole posterior surface of the limb, and the patient put to bed with the leg resting upon a slightly inclined plane. During the operation a good deal of blood was lost, a large portion of which was venous, and after its completion the patient, who had then recovered from the effect of the anassthetic agent, was very pallid and excessively prostrated. Brandy and water was freely adminis- tered and warm clothing applied. Reaction took place very slowly; about four hours after the operation the pulse began to rise and the skin to regain its warmth. The stimulants were then used more moderately. The reaction, however, was never complete, and only lasted a few hours. During the night the pulse again began to flag and the patient became more restless. Stimulants, both external and internal, were again resorted to, and used very freely, but with no effect. The system seemed to have lost its power of responding to any agent, and in spite of the most active stimulating treatment, the patient continued gradually to sink until about six o'clock the next evening, just thirty hours after the operation, when he expired. In this case I think there can be no doubt that the patient died from the shock or concussion produced by the great extent of the operation JOYNES' CASE OF OBSTRUCTION OF THE BOWELS. 271 and by the violence necessarily done to the tissues during its per- formance ; and it is interesting as shewing that chloroform will not always, whatever it may do sometimes, prevent the occurrence of this shock after capital operations. Here chloroform was exhibited very freely, so much so as to induce the suspicion that it may have had some agency in producing the fatal result. That it did really have no such agency, would appear from the fact that the anaesthetic effect had entirely passed off before the patient left the operating room, and he had entirely recovered his consciousness. The symptoms, too, which preceded death, were all those with which we are familiar as characterizing the state of shock or concussion, not those of as- phyxia or of coma. This case is further interesting as pointing out to the young or inex- perienced surgeon some of the difficulties in resection of the femur, which are not generally alluded to in the books, in which, apparently with the view to entice to operative surgery, oftentimes difficulties are concealed, with which the surgeon only becomes acquainted in the person of his first patient. Mechanical Obstruction of the Intestinal Canal, produced by Worms. BY L. S. JOYNES, M. D., ACCOMACK C. H., VA. The following example of an unusual effect of worms in the ali- mentary canal, has appeared to me worthy of being recorded, both for its intrinsic interest and on account of its bearing on an unsettled question in pathology, which merits the attention of practical men. • No little difference of opinion has long prevailed among medical authors and practitioners, with regard to the degree of importance to be assigned to the presence of entozoa as a cause of disease. While one party has attributed to their local and sympathetic irritation an almost endless catalogue of disorders, another has maintained that except in rare cases, they are quite harmless : indeed, some have gone so far as to ascribe to them a positively beneficial agency, as scaven- gers of the alimentary canal. Some apology may be be found for this under-estimate of the pathological consequence of worms, in the ac- tual infrequency of any serious effects which can be unequivocally as- cribed to their presence, and in the absurd abuse of vermifuges, aris- ing from the manifest exaggeration of the opinions entertained on this subject by the public and a portion of the profession. It is, indeed, somewhat astonishing, considering what we hear and read of the ra- vages of these intruders on the human organism, how long a physi- cian may practice, and successfully too, in cases popularly attributed to worms, without feeling once called upon to prescribe a dose of an- thelmintic medicine. But a case will now and then occur, in which some abdominal disorder, or some nervous derangement, is so plainly dependant on the presence of worms, that scepticism is compelled to give way, and pink-root, wormseed and turpentine are appealed to, of necessity. 272 JOYNES' CASE OF OBSTRUCTION OF THE BOWELS. Among the local effects ascribed to these parasites, some authors al- lude, in terms of doubt, to the possibility of their occasioning, by their agglomeration, mechanical obstruction of the intestines. Dr. Joy, of Dublin, in his very copious and learned article on the subject, in the Cyclopedia of Practical Medicine, remarks on this question : " Whether they have ever, from their numbers being very great, caused obstruction, and consequent inflammation and gangrene, is doubtful." And he quotes Rudolphi as expressing the opinion, that " They can never produce absolute obstruction, as there will alwa}~s be room for the passage of chyle and faeces. Their agglomeration, oc- casionally detected in the human intestines along with iieus, as in a case mentioned by Rahn, is probably the effect, and not the cause, of the obstruction." Grisolle, in his Pathologie Interne, after alluding to the possibility of a mass of worms causing the incarceration, and perhaps the strangu- lation of a hernia, goes on to say, "It has been in like manner pre- tended that these masses of lumbrici might interrupt the course of the fecal matters in a free portion of intestine, and produce all the symptoms of ileus; but this has not yet been demonstrated by any authentic fact. We may, however, conceive the possibility7 of such a thing. Thus, in a case reported by M. Bretonneau, a mass of worms as large as the fist distended the intestine," &c. Though Grisolle does not so state in express terms, I infer from the context that this convoluted mass of worms was only discovered after death. These two are the only authors out of a dozen or so that I have consulted, that make any distinct allusion to the point under conside- ration. The following case, which occurred under my observation very recently, although it does not offer an example of a complete and in- superable obstruction of the intestinal tube, yet goes far to justify the admission made by the author last cited, as to the possibility of such an occurrence. On the 6th of March last, Mr. J. B. brought to my office a little negro boy, aged about seven years, who appeared to be suffering se- verely from pains, similar to those of colic, for which, I was informed, no relief could be procured. Mr. B. stated, that about a week be- fore, the boy, previously in his usual health, had complained of colicky pains of the same character, but less severe, which were relieved by the aromatic stimulants commonly resorted to in such cases in do- mestic practice, and a dose of castor oil. No return of pain or other sy^mptom of disease occurred until the day before that on which he was brought to my office. Then the colic returned with increased severity, and experienced no alleviation from a repetition of the reme- dies prescribed in the first instance. Although castor oil and an ene- ma were administered, it was found impossible to move the bowels. The boy had called the attention of those around him to a " hard lump" in the lower part of his abdomen, which appeared to be the starting point and centre of the pains which he suffered. I was far- ther informed that he had vomited after taking some medicine, and had thus rejected two lumbricoid worms. JOYNES' CASE OF OBSTRUCTION OF THE BOWELS. 273 On examining the patient, I found him with a calm pulse, a coated tongue, and complaining only of pain in the abdomen, which recurred in frequent paroxysms of considerable severity, and was evidently of the nature of colic. The abdomen was very tumid and tense, but free from tenderness, except immediately in the region of the tu- mor, where the sensibility to pressure was very decided. This tumor, which was evident enough to the touch, felt at first very much like the edge of some solid growth springing from one of the viscera, or from the posterior wall of the abdomen ; but it was soon perceived to be moveable, and free from attachment to any more deeply seated solid mass. It was elongated and cylindroid in shape, and extended from near the left side of the brim of the lesser pelvis below, obliquely upwards and to the right, and terminated at a point an inch or two to the right of the umbilicus, and on a level with it. It was not quite straight in its direction, but presented one or more slight curves. Its total length I should estimate, (having made no measurement at the time,) at six or seven inches. Its thickness below was apparently about one inch ; at the upper part it gradually diminished in size, and at its termination in this direction, was not more than half an inch thick. At some points of its surface, little irregularities could be felt through the thin abdominal wall ; one of these, more distinct than the rest, imparted to the finger just such a sensation as might be produced by contact with the round, slender body of a worm. This circum- stance, taken in connection with the other characters of the tumor, and the fact that the boy had vomited up two worms the day before, left little doubt that this tumor, the cause of the constipation and colic, was in reality a convoluted mass of lumbrici, occupying a part of the small intestine. I should add, that the patient stated to me that the tumor had changed its position somewhat since he first discovered it. My prescription was in accordance with the view just expressed. I gave the boy immediately a dose of calomel and jalap, of each 5 grains, with 5 drops of oil of chenopodium, and directed that he should take 2 ounces of an infusion of spigelia and senna, with the addition of sulphate of magnesia every two hours, until the bowels should be thoroughly evacuated. The operation of the medicine was also to be promoted by the use of enemata, largely impregnated with salt. Notwithstanding the employment of these means, no action of the bowels was produced until the next morning; (the first dose of the medicine was given at noon.) The greater part of the infusion was vomited. When at length the bowels gave way, forty-six large lum- brici were discharged, all convoluted (according to the account given me) in one mass. The pains were at once relieved, and the tumor and the abdominal tension had disappeared. Here it will be seen, that although the intestinal obstruction was not insuperable, it was apparently complete, so long as it continued ; and it would not have required a much greater degree of obstruction to give rise to all the symptoms of ileus. I apprehend that so distinct a tumor of this character is rarely met with. Q1 274 martin's case of worms. A large number of 'Worms discharged from the Bowels of a Child REPORTED BY D. T. MARTIN, M. D., PULASKI COUNTY, VA. February 20, 1851, 1 was called at 7 o'clock, A. M., to visit a child, five years old, the daughter of J. W. H., in the town of Newbern, Pulaski county, Virginia. According to the account given by her pa- rents, she had been a little unwell for two or three days ; but on the day previous to my visit, she was suddenly taken with pain in the ab- domen and vomiting. As her habit was known to be costive, her pa- rents gave an enema of castor oil and warm water, as well as oil by the mouth. They also applied fomentations to the abdomen, and gave a large quantity of laudanum, (according to their statement about 3ij. in twenty hours,) without relief. At the time she was examined by me, I found her laboring under the symptoms of colic, pain in the re- gion of the stomach and bowels, the muscles of the abdomen drawn up into ridges or knots, with some tenderness upon pressure about the umbilicus, constant inclination to lean forward and lie upon the face, tossing to and fro, retching and vomiting every few minutes, throwing up a frothy mucus, mixed with a little bile ; the tongue coated with a yellowish fur ; there was also some fever, the pulse be- ing full and frequent, though compressible. I gave her calomel grs. iv., Dover's powders grs. ij., to be followed in four hours by castor oil, and applied sinapisms and fomentations to the abdomen. The oil was taken, but afterwards thrown up from the stomach. I again visited her at 2 o'clock, P. M., and gave calomel grs. ij., Dover's powder grs. i., after which she slept about four hours ; at which time she was aroused for the purpose of giving an enema com- posed of warm water, castor oil and spirits of turpentine. She now complained of a choaking, whereupon about ten drops of spirits of turpentine were given by the mouth. Some time elapsed, and she had a small passage, in which were 5 or 6 lumbricoides ; after the lapse of an hour she had a second passage, in which were 4 or 5 worms of the same kind. She then slept about two hours, when she awoke and had the third passage, which brought 114 worms, (lumbricoides,) making in all 120. I understood from her father to-day, (February 25th,) that she had another passage on the evening of the 21st inst., in which were 16 worms of the same kind, making in all 140. The novelty of this case does not consist so much in the symptoms or treatment as in the number of worms discharged. BROOCKS' CASE OF DOUBTFUL SEX. 275 Report of a Case of Doubtful Sex. BY WM. M. BROOCKS, MILTON, NORTH CAROLINA. It is so exceedingly rare to meet with a lusus natura of this kind in the United States, that it might be thought almost culpable if it were not reported. It is doubtful whether any of the primitive races of any nation ever present such anomalies. It is only among high bred classes of men and animals that such cases are to be found. Na- ture here seems to hesitate as to the sex she will choose to cast off from her generative matrix. Martha, the subject of this report, is a slave, the property of a gen- tleman of Pittsylvania county, Va. She is not a pure African, but a brown mulatto, about 24 years old ; she has the rounded limbs of the female, weighs 145 pounds, and of Dutch build from shoulders to pel- vis. She has suffered from neuralgia of her foot, and fever; has been married some three or four years, and has never menstruated. It was, therefore, naturally supposed that her sufferings were caused by amenorrhcea. When she was before me for examination in April 1850, my attention was first called to the flatness of her broad chest, and entire absence of her breasts, and as she had never had her catamenia, I inferred that her genital organization was defective ; and upon ex- amination very carefully made, both by the sight and the touch, I found this to be the fact. The pectoral muscles were as devoid of the mammary glands above them, as those of a male of the same age ; the nipple was of the ordinary male size ; face full, oval and mascu- line. The genitals presented the most extraordinary appearance. The mons veneris was covered with the usual growth of hair of pu- berty— descending from the upper part of the external labia, was a small black apron, about three inches long, like the African prepuce, which at first sight, as it tapered to a small point forward and down- wards, resembled the pendulous penis. On lifting it up, it was not round or solid, but extensible, and like a cut open prepuce. Near its junction to the labia, and just within, could be seen and felt a large clitoris nearly two inches long, and feeling like the spongy corpora cavernosa of the penis, and having the cellular membrane only over its structure. On passing through the nymphas, the finger came in contact with the upper portion of the vagina, on which the distended bladder rested, and no further ingress to the finger forward was permit- ted. In the centre of the axis of the pelvis, the finger was intro- duced, and then carried to the left side, and in this direction it was arrested. On the right side, the finger passed some three inches towards the left iliac fossa to a cul de sac, near the bottom of which a small spongy tuber like a testis gland was felt, having no scrotal covering. I then searched higher up for the uterus, and all around the sac as far as it could be reached — I could find none, neither os tineas, body or fundus. She said she had never had pains in her loins, &c, which usually precede the incipient menstrual effort at puberty. She 276 A CASE OF MONSTROSITY. had little or no desire for copulation, . and did not enjoy it, and it sometimes gave her pain. I regard this case highly interesting, physiologically, and as well entitled to be classed with those of hermaphrodism as any which I have seen reported — the absence of mammae and uterus assimilating her to the male, and the well developed external labia and nymphae to the female. A Case of Monstrosity. Church Hill, March 15th, 1851. Dear Sir, — A singular case of monstrosity came within my obser- vation some years ago, an account of which may be interesting to the readers of the Stethoscope. Mrs. B., aged 20, was delivered by a midwife of her first child in the summer of 1849, two years after her marriage. On account of the peculiar appearance of the infant, I was invited to see it. The child was a boy of the ordinary size, and regular in form and appearance, with the exception about to be stated. On the front of its abdomen, somewhat to the right side, and exterior to its parietes, was a mass of considerable size enveloped in a transparent serous membrane, and connected with the child by a single cord attached to its umbilicus. This mass was found to contain most of the abdomi- nal organs : the liver, spleen, stomach and small intestines, being dis- tinctly observed, all natural, and in an ordinary state of development. The ccecum and colon not being in the mass, must have been within the abdomen. The connecting cord comprised the oesophagus part of the small intestines, and all the vessels supplying the liver, spleen, stomach and small intestines ; all of which passed through the umbi- licus of the foetus to reach their respective destinations. This foetus was reported to have lived half an hour. Its parents enjoyed ordi- nary health, though the mother had suffered several attacks of St. Vi- tus' dance or chorea. Very respectfully, R. E. JENNINGS, M. D. A Case of Casuistry. — We observe that several persons in the land profess to have remedies for hydrophobia, the recipes for which they refuse to divulge. If a man pretends to have such a thing and has it not, he is a swindler. If he really has it, and keeps it secret, giving it only for money, and letting hundreds die for want of it, how many degrees is he in moral character above a murderer? And the same questions apply, with more or less force, to all who claim to have cures for diseases, the nature of which specifics the}' conceal. Enlightened and honorable medical men make it a point of duty to publish such discoveries as they make, for the advantage of their kind ; and we cannot wonder at the contempt with which they look upon all advertised nostrums, the components of which are secret. EDITORIAL. 277 MBITOMIAIL Hi MH§(D3iIL]LAM^©ra> State Organization. We call the especial attention of every legitimate practitioner of medicine in Virginia, to the paper published in our present Number, which emanates from the Medical society. This paper sets forth the policy of the society, so far as its own organization is concerned, and offers a sufficient guaranty to the physicians of the country, that the city members do not desire to retain the power in their own hands. The objection which has hitherto been so frequently raised to becom- ing a member, viz : that " one is unwilling to put himself in the hands of a local society, a bare quorum of which is competent, at any of its monthly meetings, to impose obligations on and legislate for all its members," is now entirely removed. The policy set forth in the paper is that which has been long asked for by country members, and very many others who desired to be- come members ; and now nothing remains but for individuals to take the necessary steps to be enrolled, and at no very distant day the constitution will be so altered as to adapt it to a general state insti- tution, holding annual meetings. This we anticipate will be done before another annual meeting, or before the assembly of a general convention of the doctors in the state. It was gratifying to observe the unanimity with which all the speakers, in a long and warm discussion on the subject in the society, urged the importance of some effectual scheme of organization. There were many differences in regard to the most effectual method and as to minor details, but the most lively interest and an unmis- takable determination to accomplish the great end was evinced on all sides. We now call upon the profession of the state, individually, to exert themselves in the cause — to agitate the subject of their own welfare among one another, and to rally around an institution through which the greatest good may be achieved. Would that our feeble pen could do justice to this subject — that we could arouse our brethren to a proper sense of the merits of this question — and that we could inspire that enthusiasm among the me- dical men of this commonwealth which would so soon tell to their in- terests and elevate their position. The most lukewarm or self-contented physician in the state needs 278 EDITORIAL. not be told of the present position of his profession, nor is it neces- sary to impress the importance of medical reform on the minds of any* The repeal of the law laying a tax on the profession of medicine, with- out protecting or even recognising it, the enactment of laws for the suppression of quackery, and the promotion of science, a registration act, a licentiate board, a proper coroner's system, and other measures of this character, are objects worthy of a strong effort for their accom- plishment; and, while individual effort, which has been and is still being exerted, must prove futile in matters which are not of a popular nature, their accomplishment is a work of no great difficulty, by united and well concerted action. In this age of progress and change, all the reforms which directly affect the popular mass " go ahead by steam ;" but movements which are not taken hold of by the demagogue politicians originate with in- dividuals, who, by combination and united effort, achieve many of the great works which mark the history of the age. Then we call again upon the physicians of this proud old state to rally around the society, and build it up until it attains that numerical strength which will give it the ability to execute those powers already granted to it by act of assembly. Place it, and yourselves through it, in a position which will command the respect of the profession at home and abroad, and which will make the public look to it as the authority on matters of the " science of life." Were not the few men who labored to establish the "Royal Society of London and Edinburgh," the "Academy of Sciences of Paris," and the other great and powerful learned bodies of the old world, told that their schemes were visionary and impos- sible of accomplishment? What has the combined effort and talent of the few originators of these works now achieved ? The history of the world and the condition of man will forever answer. Then why have we not every reason to expect the dawn of a brighter day. The race of Virginians is not degenerate, the atmosphere is not incompatible with the highest scientific achievements, and the necessity of going beyond our borders for books, education, literature, even the simplest authority in physic, no longer exists. We hold that the medical pro- fession in Virginia is as able and talented as that of any other country; why then can it not take that stand in position at home, and fame abroad, to which its worth entitles it? Let it form into a powerful association, and by a league of talent and exertion, achieve a triumph over oppressive legislation and the features of republican government, which are averse to the promotion of scientific pursuits. There is EDITORIAL. 279 already an association of one hundred and fifty of the most respectable members of the profession formed. The body contains much talent and learning, and we believe the requisite amount of energy also, to effect ultimately the objects set forth in its charter and constitution. But, as we have said, to extend its usefulness and make it the impor- tant and authoritative institution needed, it must be built up by the whole profession of the state; and to advance this end speedily, we have feebly thrown together these ideas for the consideration of our subscribers and readers who are not members. A Registration Act. Our readers will be pleased to see that a movement has at last been made in Virginia to obtain the passage of an act requiring the regis- tration of births, deaths and marriages. It may seem a little strange, that the memorial on the subject is to be sent to the constitutional con- vention instead of the legislature ; but as the latter body is generally so occupied with " mud-pike schemes" and " never has time" to at- tend to any other interests but those in which each member or his constituents are immediately interested, it has been deemed import- ant to ask the convention to engraft in the constitution a requisition of the legislature to obtain correct data on this point, both for the use of the country and their own guidance. We regard such a law as of the utmost importance to the political economist, the lawyer, the physician, and indeed to the public at large. Correct data as to the increase of native and immigrant population, statistics of mortality, and the security afforded to the rights of pro- perty by a proper registration of marriages, are objects of great mo- ment, more or less directly important to every citizen. Speaking of the same subject, the editor of the Buffalo Medical Journal says : " Medical practitioners, if they are disposed, can do much to further the passage of such a law, in the first place, by informing themselves of the advantages to be secured by it, and, in the second, by taking pains to enlighten those who are directly or indirectly instrumental in the making of laws." Hoping that the memorial to be sent to the convention will set forth the value of a general registration requisition, and that it will prove effectual in obtaining its passage, we defer fur- ther remarks on the subject until we see that paper. We may take up the subject again, in connection with our present most defective coroners' system. 280 EDITORIAL. Rushton, Clark & Co.'s Cod Liver Oil. We are requested by the gentleman who made some rough tests with nitric acid, before the Medical society, on this oil, to say that it was not his intention to bring it into discredit or to cast any imputations on its genuineness, nor was he responsible for the accuracy of the test. Lest an undue importance should be attached to the experiments made on it with nitric acid, we feel it our duty to say that little or no value can be attached to the test, and all that the experiments prove is, that different samples of the same oil (be it Rushton's or that of others,) will not give exactly the same reaction. We learn from reliable sources, that the oil of Messrs. Rushton, Clark & Co. is made at the fishe- ries, and that no expense or trouble is spared to make and preserve it pure and unadulterated. Great wonders were to be worked with cod liver oil after its introduction ; but now, that it has so often failed to cure consumption, the wish has fathered the thought of attributing its failure to the impurity of the article. This is a natural consequence of the too high estimate of an overrated medicine ; and as we have never had the furor which was so general in its favor, it may be right to say that our opinion of the oil of Messrs. Rushton, Clark & Co. is unaltered — the bottles which we have used and examined, all seem to have been perfectly pure, and we doubt not, as good as that of any other establishment. Certainly the nitric acid test recorded in our February Number, was not sufficient to cast the slightest reflection on it. We have said this much as an act of sheer justice, and nothing more. Exchanges. Our regular exchanges have been received. The March No. of the Northwestern Medical and Surgical Journal, published at Chicago and Indianapolis, contains the valedictory of Dr. Edwin G. Meek, one of its editors. Dr. M., it is said, contemplates establishing a journal in California. We wish him entire success. We have received No. 1 of the Northwestern Medical Intelligencer, which is a supplement to the above, and is intended "to furnish in- teresting medical intelligence as it transpires in the interim of the re- gular bi-monthly issues of the N. W. Journal." The Northern Lancet and Gazette of Legal Medicine, published at Plattsburg, N. Y., which has been coming to us in a very poor form, EDITORIAL. 281 obscurely printed with worn out type and set up by young appren- tices, comes in a new and much improved dress, pretty well printed and neatly covered. It is the only journal of medical jurisprudence published in America, and should be liberally patronized. The way to make it what it ought to be, is to increase its circulation and re- sources, and we doubt not but that it will grow to be a national work of medico-legal medicine, now so much needed in the United States. Terms only $1 per annum. The Quarterly Review of the Methodist Episcojml Church South, edited by D. S. Doggett, D. D., for April, is rich in good reading. The arti- cle on " Education," by Rev. Charles Collins of Emory and Henry college, is an able, clear and well-written appeal, and though wTe are opposed to sectarian schools and colleges, we recommend its perusal to the general reader. This work is handsomely gotten up, and does credit to the printers, Messrs. Colin & Nowlan of this city. The Southern Literary Messenger for April sustains its high character, and we are glad to learn that its editor has made most valuable ac- cessions to his list of contributors as well as patrons by his late South- ern tour. We have received " The eighth Annual Report of the managers of the New York state lunatic asylum" at Utica. From this interesting docu- ment we extract the following : " It will be seen that the whole num- ber of patients under treatment during the year was 816 ; of whom 171 were discharged recovered, 8 much improved, 49 improved, 108 unimproved, and 51 died — leaving 429 remaining in the asylum at the end of the year." We observe in the Journal of Insanity a notice of the " Opal," a monthly newspaper, entirely original, and edited by the patients in the asylum. The purchase of a library is contemplated by the profits of the publication. This is said to be the first effort of the character, but we are quite certain that it is not the first paper edited by mad- men. Proceedings of the Medical Association of the State of Alabama, begun and held in the city of Mobile, December 10 to 14, 1850, with an appendix. This is a handsome half bound volume, containing 156 pages. Be- sides the proceedings, constitution and by-laws, and roll of members 282 EDITORIAL. of the association, it contains the annual address of Dr. A. Lopez, the able and indefatigable president, and a beautiful valedictory ad- dress by Dr. Charles E. Lavender. Nearly 100 pages of this volume are filled with reports of diseases prevailing in certain sections, medi- cal topography, botany and other papers of interest and value. We were surprised to see a volume so large and so respectable coming from a body yet in its infancy, and not more numerous than the Me- dical society of our state. The explanation is simple ; in Alabama there is a spirit and an energy among the profession which has not as yet been aroused in Virginia. We sincerely trust that in another }rear our Alabama friends will not be ahead of us. The Physician' 's Prescription BooJc. — We have received from the pub- lishers, Messrs. Lindsay & Blackiston, a copy of the first American from the tenth London edition of this invaluable little work. We take great pleasure in recommending it to both old and young practitioners and apothecaries. The list of terms, phrases, contractions and abbre- viations used in prescriptions, the synonymes and translations of the Latin phrases used in pharmacy, and the chapter on nomenclature are all so accurately and compactly arranged in a very small compass that reference may be made to it in a moment. To apothecaries, students and young practitioners it is invaluable, and not unfrequently of great use to the most accomplished prescriber. GF° The Editor of the Stethoscope will be absent from the city, in attendance on the American Medical Association at Charleston, S. C, from the 1st to about the 15th of May. During his absence Mr. Win. W. D unnavant will attend to any business connected with the journal. Mr. D unnavant can be found at the publishing office, corner of Bank and 10th streets. Medical Society of Virginia. April Meeting. After the consumption of much time in ballotting for new mem- bers, and reading letters of application, the subject for the evening came up for discussion. Some exceptions were taken to the language used by the committee in that part of their report relating to the physiology of anaesthesia. After a short defence by the chairman, a motion prevailed adjourning the discussion over for a week. MEDICAL SOCIETY OF VIRGINIA. 283 A resolution was passed appointing a committee of three, on the part of the society, to act in conjunction with a committee of the Medical College and any other body, for the purpose of memorializ- ing the state convention on the subject of a general system of regis- tration of births, deaths and marriages. After the transaction of other business of local importance, the so- ciety adjourned over for a week. The number of members and visit- ers was so great that the propriety of procuring a larger hall for the future was spoken of. Called Meeting — April 19. Pursuant to notice given, and in accordance with a resolution adopted in February, requiring this subject to be acted on at called meetings, the society met to receive the report of the committee on state organization. From the full attendance on the occasion, we re- mark the lively interest taken in the subject. A report and two series of resolutions were presented by the com- mittee. A substitute was offered on the part of the minority of the com- mittee. Two resolutions, recommending the formation of local societies, and a mother association, with delegations from them, were offered in lieu of the two reports. After a long and animated discussion the above substitutes were rejected, and the following paper was offered and adopted, by a very de- cided vote, as a substitute for the committee's report. It was ordered to be printed in the Stethoscope, and the society adjourned. "The Medical Society of Virginia, observing with great satisfaction the success which has attended united effort for the promotion and ad- vancement of the science of medicine in other states of our Union, have taken the subject under consideration, with a view of devising some plan by which a general organization of the profession throughout Vir- ginia could be effected. " After a careful- examination of a number of plans which have been suggested, we are of the opinion that the one which was reported by a committee appointed by the state convention assembled at Rich- mond in 1S46, to take into consideration the same subject, and which the Medical society, by resolution of the same body, was appointed a committee to carry into effect, is the plan which is most practica- ble, and, when once effected, will be most permanent, and thereby contribute more to the advancement of our profession than any other which has been proposed. It is, in a few words, this : That the medi- cal men throughout the state, whose qualifications are such as enti- tle them to membership, be urged to enrol themselves members of the " State Medical Society," a body organized under an act of in- corporation, passed in 1824, and now in operation. That when a sufficient number from different portions of the state shall have been thus enrolled, to constitute it a fair representative of the medical pro- fession of the state, it shall assemble once a year to transact such 284 MEDICAL SOCIETY OF VIRGINIA. business, and engage in such exercises as will be promotive of the general good of the profession. We regret to say that this, like many other great plans of improvement which have been commenced in our state, has not realized the expectations of its originators — not from any defect in the plan, however, but from a variety of causes, not the least prominent of which has been the want of that zeal and perseverance with which they should have been prosecuted to ensure success. We hail the interest which has been recently mani- fested by prominent men in different parts of the state, as well as by members of our society, as an indication that a better day is dawning. " There are existing other causes which have operated to prevent the success of this plan, and to which we deem it of importance to refer. They are feelings of prejudice which have grown out of the position which the physicians of Richmond have occupied in this society. While these appear strange to us, who are familiar with the history of this society, and understand the position which we occupy in it, we confess that they might naturally enough have arisen in the minds of those unacquainted with the circumstances which forced us to take this position. We feel assured that a short explanation upon this point will be all that is necessary to remove these feelings. In 1824, a number of medical men, principally resid- ing in Richmond, conceived the idea of organizing the physicians of the state upon this plan. They applied to the legislature and obtained a charter, which gave them the privilege in general terms of doing any thing which they might deem necessary for the promotion of medical knowledge, provided it did not conflict with the constitution or laws of the United States, or the commonwealth of Virginia. They did not suc- ceed, however, in this organization. It was regarded as a novel propo- sition, and one the practicability of which had not been demonstrated in this portion of our country — that such a thing was indeed premature for our state of society. Its advocates, seeing that they could not at that time carry out their original design, and that as there were enough mem- bers of it in Richmond alone to retain the charter, provided they held meetings as a medical society, determined to convert it temporarily into a local society, and instead of meeting annually, to meet once a month, retaining, however, the original name, " State Medical Society of Virginia," hoping that at some time the original design might be revived under more favorable auspices, and carried into effect. We would hope that that time is not far distant — and we do hereby pledge ourselves that, when it does arrive, we will cheerfully yield to the physicians throughout the state any local right which we may have derived by this temporaiy possession of it. The physicians of Richmond, to keep in existence the interesting local society which has sprung up under this organization, will resolve themselves into a local society proper, and meet under a new name, retaining, however, if it is their pleasure to do so, the constitution and by-laws by which we are now governed. We deem it inexpedient, at this time, to carry into effect this separation, inasmuch as our society, as now organized, is the most efficient committee that could be appointed to carry into effect this general organization ; for, according to our con- SELECTIONS. 285 stitution, we have now the power to elect members to this state me- dical society at each one of our monthly meetings, a facility which the experience of a few meetings, held since this question of organi- zation has been revived, has shewn to be a very important one. We lose this facility by immediate separation, for those members could only be elected at annual meetings. We therefore propose to retain the position which we now occupy, until this organization shall have been so far effected, as to place beyond doubt its ultimate success : we will then withdraw ourselves, and occupy the same position rela- tively to the state society as other local societies elsewhere, the only connection with it being the privileges of membership. We feel assured, from the success of efforts recently made, that, if all the members of our society and the profession generally will give a cordial support to this plan, that we shall, in less than twelve months, have succeeded in organizing a body, consisting of a number sufficiently large, and endowed w7ith ample power, to effect those reforms which are necessary for the protection of the rights, and the maintenance of the honor and respectibility of our profession." SSP1 The twenty-seventh annual meeting of " The Medical So- ciety of Virginia" will be held in the hall of the Richmond library association, corner of Main and 11th streets, on Tuesday evening, May 20th. The chair will be taken at 7£ o'clock, P. M. P. CLAIBORNE GOOCH, Sec. The Nature of Evidence, and the Requisites for the Credibi- lity of Testimony. BY ASA D. LORD, M. D., COLUMBUS, OHIO. All the knowledge we possess, or are capable of acquiring, may be referred to one of the three following heads : First, those primary truths given us by reason, the various operations of our own minds as revealed by consciousness, and the thoughts and opinions formed by the combined action of the several faculties of the mind in the pro- cess of reflection ; second, the information acquired through the me- dium of the senses in the processes of observation, experiment, or in- vestigation ; third, that which is derived from the testimony of others as the result of their experience, observation, or research. Hence, it is proper to name the exercise of the senses, the operations of our own minds, and the evidence of testimony, as the sources of know- ledge. To the last source we are indebted for the greater portion of the information we possess, and for nearly all that which we value most highly. In history, geography, and astronomy, in chemistry, and nearly all the branches of natural science, we must depend, mainly, upon the testimon}' of others for our information. Few have the op- portunity to travel, and view for themselves the localities described by the geographer and the historian, the instruments for seeing the 286 SELECTIONS. wonders revealed by the telescope and the microscope ; and few have either the time or the conveniences for performing the experiments which substantiate the great truths on which the whole superstructure of many of these sciences rests. From these considerations, it is obvious that some acquaintance with the nature and laws of testimony is important to every indivi- dual; but perhaps no class of persons, except those connected with the bench or the bar, are more frequently placed where such an ac- quaintance is of the utmost importance, than those engaged in the practice of medicine. Not only is the pl^sician often called to the stand under circumstances of the deepest interest to all concerned, and when the nature of his testimony is to decide questions of the highest importance, and the manner in which it is given may do much for the credit or reproach of his profession — but the new and conflicting views and theories in regard to the nature and causes of disease and the mode of treatment, which are constantly claiming his attention, demand, on his part, a familiar acquaintance with the laws of belief, and the ability to apply them to the fects and argu- ments by which these theories and opinions are sustained, with clear- ness of perception and correct judgment, if he would not be a mere empyric in his practice, and receive his opinions and theories ready- made, from those whose lead he prefers to follow. Nature of Testimony. The office of testimony is to give to us the same information we should obtain by the use of our own powers of observation and in- vestigation, in regard to facts and phenomena, which have not come under our notice ; it is employed to establish the existence or validity of facts, not to sustain opinions or theories. Opinions must be sub- stantiated by arguments: the validity of arguments must be tested by the rules of logic. Theories must be sustained by facts. In or- der that a theory may be regarded as the law by which the facts for which it professes to account are governed, it must be consistent with all the facts and phenomena pertaining to that subject. The exist- ence of one single, well-attested fact at variance with a theory, is sufficient to destroy our confidence in it altogether: not only must it be thus accordant with the facts, but it, or an identical one, must be absolutely demanded by them. Thus, the theory of gravitation is not only consistent with all the facts for which it professes to ac- count, but it, or a similar theory, is imperatively demanded by them ; hence, this is without hesitation denominated the law of universal gravitation ; but the same is not true of either of the two theories which have been proposed in regard to the nature of light. Har- vey's theory of the circulation is also exactly in point ; it was de- manded by the facts known, or easily ascertained, in regard to the structure of the heart, the arterial and the venous systems, the pul- monic and the systemic circulation: the same is true of the modern theory of the nervous system, the facts demand the existence of the distinct classes, denominated nerves of sensation, of voluntaiy mo- tion, and of organic life. SELECTIONS. 287 The existence, or the validity of facts which have not come un- der our own observation, must be established by testimony. Al- leged facts may be of two kinds, impossible or possible ; no amount of evidence can justify us in believing an impossible thing : only the latter, therefore, can be substantiated by testimony. We may be called to believe strange things, those which are marvellous, and, with our present knowledge, unaccountable ; but they must, at least? be possible, they must not involve any palpable contradiction, or manifest absurdity. We are accustomed to speak of impossibilities of two kinds, physical and moral: in the former are included things which are contrary to the known laws of the natural world ; as, that a body should exist in two places at the same time ; that a circle and a square, or a cube and a globe, should be the same thing : by moral impossibility is meant, a very high degree of improbability. The term 'physical impossibility, or the phrase physically impossible, is also employed for describing mathematical and other absurdities ; as, that two and three should equal seven ; that an idiot should demon- strate an intricate problem ; while the statement that one who had been an idiot up to the age of twenty, had from that time manifested the possession of an intellect of the highest order, would be so im- probable as to be considered a moral impossibility. Possible facts may be classified, first, as probable or improbable, when they do or do not accord with our experience, or the results of our observation : second, as credible or incredible, when they do or do not correspond with the known powers of the agent to which they are ascribed, with the laws in accordance with which they are supposed to occur, or by which the producing causes are governed. To classify accurately, with reference to these distinctions, the statements made in the reports of remarkable cases or wonderful cures, and the certificates of the inventors of specifics, and the ven- ders of nostrums, and the graver assertions of those who are sup- posed to have a claim to credence, is often a work requiring no little care, and no small degree of critical acumen ; for, while an indis- criminating credulousness is indicative of a weak mind, incapable of thinking or judging for itself, a tendency to indiscriminate skepticism is equally characteristic of a bigoted mind, which reasons incor- rectly if at all, or upon imperfect data, or from unsound premises, and makes its own preconceived opinions the test of all new theo- ries, and its limited observation the standard of probability, by which all alleged facts are to be tried. This is the disposition which, when told that ficts do not accord with his favorite theory, leads the holder to exclaim impatiently, "So much the worse for the facts then ;" or like the King of Siam, who, when told by a Dutch travel- ler that in Holland, water sometimes became so solid that an elephant might walk on it, replied, "I have believed many extraordinary things which you have told me, because I supposed you a man of veracity ; but now I know that you lie." With a cultivated mind and the ability to discriminate clearly, we can readily see how the king just named, or any other person who had ever seen the metals liquefied by the application of heat, and again become solid when it ^88 SELECTIONS. was abstracted, might have regarded the traveller's statement, not only as possible, but as credible, and even highly probable, without reference to the credibility of the traveller. In the same manner, we can easily conceive how Archimedes, or any other similarly intelligent philosopher of his time, might have given credence to a description of the feats of a steam engine, or any other piece of modern machi- nery, while his ignorant countrymen would have regarded it as en- tirely fabulous. In order to prove the existence of facts or the occurrence of events of which we have not personally taken cognizance, it is desirable that they should be substantiated by the concurrent testimony of two or more individuals; but cases frequently occur, in which, from the cir- cumstances, this is impossible, and our opinions must be formed from the testimony of a single witness. In such cases, it is necessary that the witness possess most or all the characteristics needed to render his testimony valid ; and hence the importance, to every person, of a knowledge of these characteristics. 'Ov Requisites in a Single Witness. The most important requisites for the credibility of testimony from a single individual, are the following : 1. Unexceptionable moral character; or, at least, a character for veracity unimpeached and unimpeachable : the importance of this is too obvious and too well understood to need comment. 2. That he be disinterested in the present case ; that he have no private or personal ends to accomplish. 3. That he possess a capacity for understanding the facts in regard to which he testifies : the savage would be but poorly qualified to give information in the processes required in the mechanic arts ; the man unacquainted with human anatomy, physiology, and patho- logy, would be equally incompetent to testify to the facts revealed by a post-mortem examination. 4. He must have had full opportunity to observe, for himself, the facts to which he testifies : this will, of course, exclude every thing like "hearsay," or second-hand testimony. 5. There must be satisfactory evidence that adequate attention was given to the facts at the time of their occurrence, and that the memory of the witness does not deceive him. This is a requisite of the utmost importance ; the testimony of many a witness is invalida- ted, and his character for veracity rendered questionable, by the ma- nifest want of attention to the facts, and the confused remembrance of them indicated in his statements. 6. His testimony must be given in plain, unequivocal terms. Nothing is more directly calculated to discredit the testimony, or bring suspicion upon the character of the witness, than the use of ambiguous expressions ; and it adds no weight to testimony, to have it expressed in technical language, when common and perfectly intel- ligible terms may be employed with equal accuracy and propriety. 7. There must be consistency in his statements, and between them SELECTIONS. 289 and his conduct. Had Columbus manifested any unwillingness to re- turn to this continent, or had he even seemed indifferent to the under- taking of another voyage in this direction, who would have believed his statements in regard to the discoveries he had made ? Corroborating Circumstances. Aside from these characteristics of the witness himself, there are often circumstances entirely unconnected with his character, his ca- pacity; or his conduct, which have an important bearing upon the credibility of his testimony ; among those which tend to confirm his statements are the following : 1. The entire absence of all motives to misrepresent the facts, or to give false testimony, and especially the presence of strong motives of an opposite character ; under such circumstances, we often feel impelled to receive testimony without reference to the moral charac- ter of the witness. 2. That the witness be aware that he is open to conviction if his testimony is false. 3. When the facts stated, though unknown before, accord with others of a similar nature, already known. 4. When, though without parallel or analogy in our experience or observation, they accord with the known powers of the cause alleged to have produced them. 5. When the facts stated develope laws not previously discovered, or reveal properties or powers in the alleged causes, or the exist- ence of relations, before known ; here, the farther removed from ex- perience, the greater the probability of the truth of the facts : be- cause, if not true, they would have been unknown to the witness. One of the earliest Greek historians mentions that a ship's crew pro- fessed to have sailed from the Red Sea, around the southern extremity of Africa, and returned by way of the Straits of Gibraltar; but adds, " We know they do not tell the truth, because they affirm that, during a great part of their voyage, the sun appeared north of them at noon !" 6. The entire absence of all conflicting or contradictory testimony, and the knowledge of facts which cannot be accounted for, except by supposing the statements true. Testimony from two or more Witnesses. When two or more witnesses appear to testify to the same facts, it is important, 1. That each possess all the requisites previously named. 2. That they concur in their statements in all essential particulars. The following circumstances tend to increase our confidence in concurrent testimony thus given. 1. When one witness mentions facts or particulars omitted by others. 2. When coincidences occur in regard to which the nature of the case and their circumstances, or relations to each other, preclude the idea of collusion. 3. When statements apparently contradictor}7', are reconciled by a more full acquaintance with the subject. 32 290 SELECTIONS. 4. When the characters of the witnesses, and their relations to the subject of investigation, are materially different, and hence their tes- timony, if influenced at all by personal feelings, would vary. 5. To these may be added, in regard to recorded testimony of every kind, one of the strongest corroborating circumstances is, the general assent to its truth of all those to whom the statements were originally made, and during whose life-time they wTere recorded. It will be obvious, without remark, that the views here presented may be applied in every department of investigation or research. To those already familiar with the subject, it is unnecessary to say that the writer claims very little on the score of originality : his object has been to arrange, in a form as condensed as possible, and convenient for reference, an outline of the subject, for the benefit of those who may not have time for consulting the voluminous legal treatises upon evidence, and who may wash to be able to form for themselves opi- nions which they can defend, as wrell as state and illustrate, in regard to every subject to which their attention is directed. Preliminary Examinations of Students in Medicine. The successful study of the medical profession requires a combina- tion of mental powers and acquirements, which can only result from a sound and judicious course of training, commencing in early youth, and continued throughout the career of the practitioner. No sensible man believes that his medical education is completed because he has passed his examination, and is launched into the duties of professional life ; he feels that he still is, and ever must be, a student, so great is the field of observation which he is ever compelled to explore, so va- rious and so complicated are the diseases w7hich he is called upon to treat, so heterogeneous are the theories and the modes of practice which he is called upon successively to examine, to adopt, or to reject, and so numerous and important are the discoveries in every branch of the healing art which teem in this prolific age of intellectual progress. But to steer his course advantageously towards the haven of truth, and to escape the shoals and quicksands which impede and obstruct his onward career, he must possess a mind richly endowed with phi- losophical truths, habituated to systematic discipline, ready to wel- come what is valuable, prepared to abandon what is worthless. To induce this exalted tone amongst the members of the medical profes- sion, there is not a more powerful incentive or auxiliary than a com- prehensive system of preliminary education. The mind which is once imbued with correct principles of thinking and acting will not easily abandon the habits of early life, which, on the contrary, will grow stronger and stronger as age advances : " duo semel est cuibuta recens servabit odorem Testa diu." Impressed with the value and necessity of an efficient preliminary education in forming the character of the medical practitioner, it has long been the practice at some of the examining boards to require the SELECTIONS. 291 candidate to produce evidence of a knowledge of classics and mathe- matics, not because such an acquisition is absolutely indispensable to the study of medicine as an art, but because the possession of such information of these branches of education necessarily involves, on the part of the student, a certain amount of that information which is essential to make him a scholar and a gentleman. Our own views upon this subject are very latitudinarian. We have no deep-rooted prejudices in favor of Latin and Greek as the only portals to the tem- ple of knowledge, and should be quite willing to see their places sup- plied by the modern languages, such as German or French ; but it is obviously necessary that the majority of the world should agree upon certain elementary branches of instruction to be employed in the edu- cation of youth ; and so far as the learned professions are concerned, the classical languages have hitherto held the primary place. Again, in the discipline of the mind, the mathematics, which include the sci- ences of number and of measurement, are unquestionably of immense importance; but a correct knowledge of logic, or the art of reasoning, is equally valuable, and might very well be substituted. There can be no question as to the relative facility with which the sciences strictly belonging to medicine may be learned and apprecia- ted by the well-informed as compared with the ill-informed student: The former readily grasps the facts and reasonings presented to his notice, arranges them under their proper heads, and stores them up for future use; the latter finds himself continually in a labyrinth of perplexity, and is not only unable to follow out any train of reasoning, but is even ignorant of the meaning of the technical terms which are employed by his teachers. But it has been a common error to demand the evidence of an ac- quaintance with general literature or science at the close of the pe- riod of medical pupilage, instead of requiring it, as in our opinion ought to be the case, at the commencement : and hence the student has too often been compelled to combine the elementary studies of grammar and syntax with the proper pursuits which belong especially to his medical curriculum. We conceive that every student should be required to give evidence of possessing a good general education before he enters upon his medical studies, and then the system of grinding Latin grammar into the heads of men who ought to be employed in the hospital and the dissecting room, would be entirely unnecessary. The system adopted at the University of London, of requiring that all students, for whatever profession they may be destined, should pass the matriculation examination, is one that deserves the highest commendation; and we should rejoice to see the day when every medical student would cheerfully present himself at this preliminary tribunal before entering upon his anatomical and medical courses. If the College of Surgeons of England were to require at least some pre- liminary knowledge from those who seek its diploma, they would neither lower their own dignity nor degrade their members in public estimation; and if the demand on the part of the College for a smat- tering of Latin, or German, or mathematics, from those to whom the lives of the community are to be entrusted, should perchance exclude some few persons from the membership, the result would not be par- 292 SELECTIONS. ticulaiiy disadvantageous either to the public or the profession. The society of apothecaries have for several years required a knowledge of Latin, at least, from their licentiates ; and we could wish that they would so far modify their present plans as to allow students to come up for examination in classics at a very early period of their hospital studies, or before they have commenced them, by which means a double good would be effected ; the student would be better able to comprehend the instructions of his medical teachers, and he would be enabled to pursue his after studies without being compelled to mingle them with elementary pursuits, which, however useful and important to a schoolboy, are out of place in a medical school. The prelimi- nary knowledge is as important to the medical practitioner as a scaf- folding is in construction of a house ; but it is just as absurd to teach medicine first and Latin afterwards, as it would be to try to build a house first, and afterwards to erect the scaffolding. — Lancet. Sick Headach cured by full Inspirations. — When a medication is based upon the experiments made upon himself by an honorable pro- fessional brother, it is far better, in reporting it, to give his own words. We will then simply publish the communication of M. Ta- vignot upon the new therapeutic agent in the cure of this painful, if not dangerous disease. " It was in the following manner that I discovered the efficacy of this new and apparently strange method for the cure of this affection. In October last I was attacked with pain and weight in the head, ano- rexia, a physical and moral prostration, &c. Experience taught me that I had to remain in this state for twenty-four hours. I concluded that this peculiar state of the nervous centres might depend upon a stagnation of blood in the venous sinuses of the dura-mater, as M. Auzias Turenne supposes, or upon an imperfect aeration of this fluid. I immediately commenced respiring freely and fully during several minutes. I perceived a sensible relief, which induced me to continue, and in a short time I was cured. I got up and undertook my usual occupations, as I felt but a slight pain in my temples, which vanished in a quarter of an hour. This result was doubly agreeable to me, as it furnished me with a new and practical remecfy. In ten persons, upon whom it has been tried, one half have found instanta- neous relief, and in the others there has been an amelioration, or a complete failure. However, upon interrogating with care those who were not relieved, I am convinced that they did not have genuine sick headach: they had a neuralgic pain of the head, but it was not ac- companied with that profound prostration and melancholy that I have mentioned as characteristic of the disease. It seems to me to be use- less to search for the modus operandi of full and profound inspirations in the cure of sick headach. It is evident that by this means the venous circulation is accelerated, and the chemico-physiological act of hematosis is hastened. Then the explanation of the success of this new method is in one or the other of these conditions, or perhaps in both. — South Med. fy Surg. Jour.— from TJ Observation. SELECTIONS. 293 [From a Letter from the Editor of the Boston Medical and Surgical Journal.] On Medicine and Surgery in Egypt. As mentioned in some preceding letters, a variety of medical adven- turers hover in and about Cairo and Alexandria, because, in some cases, there seems to be not another place to rest the soles of their feet. Like Noah's dove, they go abroad from their homes in Europe, in the strength of hope, the profession being multiplied there beyond the de- mands of the people. They thus sometimes fly almost to the ends of the earth — and it will be admitted Egypt is about the terminus ; but, unlike Noah's dove, if they fail of success, they cannot conveniently return to the ark from whence they went out. Some of them succeed admirably, provided they obtain the patronage of the merchants among their own countrymen here, for they have the wherewithal to increase the store of a physician. The security which Mahomet Ali gave to the lives and property of foreign merchants, induced multi- tudes of them to settle in this granary of the old word. English phy- sicians are the best paid ; and the Italians, worthless as some of them are, the next. Arabs, even sheiks, the heads of villages, mechanics, shopkeepers, and others, possessing means, are miserable paymasters to the physicians ; still they are always wanting advice and surgical assistance. "Only cure," is a common remark, " and the best cow in the herd, my courser," &c, are promised to be forthcoming ; but they never come. Those who have most reputation in their view — those who make the blind see, by pricking their eyes, and stop the growth of scrotal enlargements — a complaint that is quite prevalent — have no security of payment for their services till a certain sum in current piastres is laid upon the table. What is thus obtained is all that ever will be paid them, and consequently the course is quite jus- tifiable. It strikes me that an accomplished dental surgeon would find his account in settling at Alexandria. If any dentists are there now, they can have no extended reputation, or I should have heard of them. It would be quite impossible to realize such prices, however, as they obtain in the United States. Apothecaries seem to have good picking, particularly in Alexandria, where they have possession of one side of a street. Perhaps, like spiders in a bottle, they live on each other — for it is not by putting up prescriptions for Arab customers that they thrive. By combining su- gar plums, tooth-washes, fancy soaps, and such kinds of showy nick- nacks as have gradually crept into drug-shops all over Christendom as well as here, the paras are probably gathered quite rapidly. French medical works are most in vogue: how much they are studied, is another matter. As for keeping up with the improvements and discoveries of the day, no one appears to think of it. Consequently a copy of any medical journal is a rarity. Possibly one may be taken by some of the English physicians ; yet 1 have not seen one in any office in Egypt, to my recollection. Nor does any one appear ambi- tious to record or publish the results of his observations on the diseases of the country. 294 SELECTIONS. A few days before sailing from Boston, in April 1850, a letter was received from my much-esteemed friend, Dr. Musse}7, of Cincinnati, urging me to investigate that horrible disease, leprosy, and while at Athens, ascertain respecting the prevalence of acute rheumatism there during the last 2500 years — and lastly, to enquire concerning the ex- istence of intermittent fever, of five days' interval between the parox- ysms, for the same long period. I have not been unmindful of the re- quest. When I reach Damascus, the first will be looked after ; and in Greece, whoever has a twinge must expect to be mulled over pretty thoroughly, on the doctor's account. Some of the old aches that were engendered in myself by years of exposure in an open boat during my connection with the external health department of Boston, give occa- sional intimation of their whereabouts between the shoulder and the elbow of the left arm, even in the bland climate of Egypt. This is the more extraordinary, as during the warm weather in New England there was a complete exemption from rheumatic troubles. As an in- dication of the temperature here during the whole of January, it may be mentioned that the musquitoes are so pestiferously annoying, that the bed must be secured by a muslin net, or the sleeper would find himself sucked as dry in the morning as one of the baked monks of St. Bernard. I cannot deny myself the pleasure of adverting to Dr. Mussey's widely-promulgated anathemas against the use of tobacco — the ha- bitual use of which is as much objected to by myself as by that staunch apostle of temperance in eating, drinking and smoking. But with all his zeal, his philanthropy, his bold arguments and cogent reasoning on this subject, in Egypt he would find stumbling-blocks in the way of his con- clusions, that would be worse to manage than a hogshead of the best Kentucky in the market. Men, from childhood, smoke incessantly in Egypt. They smoke everywhere and under all circumstances. There is no cessation — not an hour when a cloud of curling smoke is not as- cending. It is the first and prominent civility to hand a pipe — and smoke you must, or suffer under the imputation of being no gentleman ; and were that good man of Cincinnati sitting where this sentence is written, he would himself smoke, like every one else here. People live long enough, in all conscience, notwithstanding this everlasting smok- ing ; for they outlive their usefulness — outlive everything but animal wants — live, some of them, till everybody wishes they were dead ! I have not been an inattentive observer of the smoking mania in Ger- many, and other parts of continental Europe ; on the contrary, a strict inquiry into the moral and constitutional effects of the habit, very ju- diciously called a vice, was instituted as I travelled from kingdom to kingdom where it prevailed ; and I have arrived at the gratifying con- clusion that if persons wish to smoke, they maj'", and I shall not waste my breath in warring against the habit. Another kind of smoking is practised in Egypt, and probably in Syria, unknown to us in America, viz., that of Indian hemp. Cigars are charged with it, and there are apartments where individuals may go and draw in, through a long pipe-stem, a kind of smoke that exalts a dirty, barefooted rascal into an imaginary prince. In a few minutes SELECTIONS. 295 he sees the gates of a Mahomedan paradise, gazes wildly towards the sky, and laughs till all consciousness passes. away, and he falls into a lethargy of considerable duration. I suspect it is hemp, and not opium as generally supposed, with which cigars are drugged, and made the instruments in the hands of designing men, in London and other great cities on the Continent, for the perpetration of many dreadful crimes. I have collected many curious and novel facts, illustrative of the die- tetic regimen and social habits of Arabs, Jews, Nubians, Abyssinians (slaves and freemen) with whom I have had as much acquaintance as is desirable, in their own countries : but how or when they are to be used, is uncertain. A knowledge of them would sadly unhinge some excellent theories of our regenerators of society. Were they to attempt the introduction of some of their hobbies into these countries, they would be laughed at as fools ; and after the blush of mortifica- tion at the absurdity of their moonshine propositions had subsided, they would laugh themselves at their own stupidity and narrow-minded conceptions of the elements of humanity. On the way to Beyroot, Feb. 4, 1851. Payment for Medical Services. The following extract should convince all men who attempt to meet competition by low charges, how utterly futile such a method proves : Remuneration of Medical Attendants in France. M. Amedee Latour, editor of U Union Medicate, has lately pub- lished a very instructive article on the above subject. From this con- tribution we find that the majority of medical men, especially in the country, are lamentably paid, the principal cause of this sad state of things being the unfortunate practice of underselling one another. There are surgeons in the country who will pay a visit for five pence, and even two pence half-penny ; attend a midwifery case for twenty pence or half-a-crown ; set a limb for ten pence, &c. &c. In Paris the evil is likewise very great, it being well known that some unscru- pulous characters offer their services underhand at a lower rate than the usual attendant has fixed, that rate being indeed low enough, as it ranges from twenty pence to half-a-crown a visit, even in Paris. At Toulouse a club was formed some time ago, composed of a thou- sand individuals, who offered a surgeon one thousand francs (<£40) a year to attend all the members. He, being a beginner, accepted these miserable terms; seeing which, a professional brother went and offered his services for half the sum. But the latter was soon outwitted, as a third sprang up and offered to do the work for .£10 a year! M. Latour throws out the idea that a minimum should be fixed and agreed upon in each locality ; but we fear that he did not consider human frailty sufficiently when he thought of that expe- dient.— [Lancet. 296 SELECTIONS. We are of opinion that whatever price a practitioner sets on his services, to that price he should invariably adhere. The physician or surgeon who requires a sovereign as a fee may perhaps venture to ac- cept a half sovereign from persons of limited means ; na}r, in some cases, he should do so ; but the practitioner who values his services at five shillings or half-a-crown should never accept a farthing less than his customary charge. Far better to treat parsimonious persons as paupers than allow them to go forth boasting of their success in pursuit of cheap doctoring. Such people can be easily taught that they must conform to a rule of trade, they being generally them- selves traders, and if they cannot be taught, the sooner they are got rid of the better. — [Dub. Med. Press. Dr. Robert Lee and Dr. Simpson. To the Editor of the Lancet. Sir — At a late meeting of the London Medico-Chirurgical Society, it was stated to the society by Dr. Lee, that at the dissection of a case in which ovariotomy had been performed by Mr. Lizars, some twenty-five years before, I considered the tumor ovarian, until the two ovaries were shewn me at the dissection. The following letter to Dr. Lee will shew how very far he was from stating what was true, when he made such a statement : Edinburgh, 52 Queen street, Feb. 3, 1851. Dear Sir — At the last or one of the last meetings of the Medico- Chirurgical Society, you adduced a private letter sent to you b}r Mr. John Lizars of Edinburgh, stating in relation to one of his published cases of ovariotomy, that " Dr. Simpson, on inspecting it, pronounced it to be ovarian, but in looking to the ovaria, they were both found healthy." Mr. Lizars was not present at the dissection ; and the statement which you thus gave to the Medico-Chirurgical Society was altogether incorrect. Dr. Myrtle had charge of the patient and of the dissection; and I enclose to you a letter from that gentleman, stating that I was the first to point out at the dissection that the two ovaries were unaffected. The tumor was, as you are aware, a fibrous tumor, arising from the fundus of the uterus. Let me merely add, that I have long given up the idea that ovarian tumors (such as this was supposed to be a quarter of a century ago, when Mr. Lizars operated) ever remain stationary for any long term of years. Fibrous tumors, however, of the uterus, often enough re- main latent, and without increase for a great length of time. And this simple distinction led me, a priori, to doubt whether the tumor m question could possibly be ovarian. I write this, in order that you may, at the next meeting of the Me- dico-Chirurgical Society, set the society right on a point which you SELECTIONS. 297 thus thought fit to lay before them. I scarcely could have fancied it worthy of being mentioned to such a society, whether I was right or not right at the dissection and diagnosis of a case. But as you con- sidered it worthy of the observation of the society that I was in error in regard to the case, you will, I doubt not, now equally consider it worthy of their observation, that it was you who were inadvertently in error in making the statement. Yours, &c. To Dr. Lee. J. Y. SIMPSON. Dr. Lee having refused to correct in any way the mis-statement which he made, I hope the fellows of the Medico-Chirurgical Society will pardon me taking the present as the readiest means of correcting the erroneous statement publicly made to them by one of their own body. Again, at the last meeting of the Medico-Chirurgical society, (as reported in your journal,) it would appear that Dr. Lee thought fit to misrepresent to the society another case in which I was concerned, and published an account of. Dr. Lee stated to the society, that in a case of mollities ossium, I intended to perform the Caesarian section, " when the sacrum was straight above, so that its promontory did not probably encroach upon the brim ;" hence attempting to lead the fel- lows to the untrue inference that the pelvis was not contracted to such an extreme degree as to require such an operation. But he delibe- rately suppresses the two facts ; first, that the outlet was so greatly contracted, that it was under an inch in its transverse diameter, and about two inches in its conjugate ; and secondly, that the dead and putrid child was so diffluent and decomposed, that it was passed readily after its birth, through an artificial aperture one-eighth of an inch in width, and two and three-eighths of an inch in length. Perhaps most of your readers may think it unnecessary to point out these two instances of misrepresentation on Dr. Lee's part ; the one consisting in a suggestio falsi, which he refuses to recal, and the other presenting an equally marked instance of the swpprcssio vert. But I trust they will excuse my alluding to them in your pages, as 1 have no other way of refuting publicly the ridiculous and disengenuous charges which they contain. They afford, also, I fear, only two com- mon instances of the type of misrepresentation in which Dr. Lee in- discreetly indulges himself in those painful fits of furor obsfetricans against all his professional brethren, under which he, from time to time, so unhappily suffers. Is it right for the Medico-Chirurgical so- ciety to abet these morbid attacks in Dr. Lee? Is it kind to Dr. Lee himself to encourage him in their open and public manifestation? Yours, &c, J. Y. SIMPSON. Edinburgh, Feb. 1851. 298 SELECTIONS. Sale of the Chemical Apparatus belonging to the late Prof. Webster. — The various appliances of the late Prof. Webster's laboratory were sold at auction last week, by Mr. Leonard, Tremont Row. The most notable article in the collection was a Magnet once owned by the dis- tinguished French chemist, Lavoisier, who, it is well known, was be- headed during the great French Revolution. After various fortunes it came into the possession of Prof. Webster, by whom it was highly prized. It seems to have been owned by men who have met with a most unfortunate end. It was purchased by Mr. Francis Alger of South Boston, for the trifling sum of $ 5 25. Its rare history gives it a value entirely beyond any intrinsic virtue. At the auction of Prof. Webster's library, previous to the above, his name was erased from all the books except one, and which book is now in the possession of a well known literary gentleman of this city, who has one of the largest collections of autographs of any person in the country. This book contains the professor's signature, written in a bold and dashing man- ner. It escaped the detection of the family, by one of the leaves ad- hering to the cover. — Boston Meol. and Surg. Jour. Enlargement of the Aponeurotic Orifice of the internal Saphena Vein in cases of Varicosed Veins of the Legs. — We condense from the Bul- letin Gen. de Therap. the following particulars in relation to this ope- ration, which was performed a few years ago by M. Herapath, of Bristol, but a full report of which was not made. M. Malgaigne has recently performed the same operation, and reports the case as fol- lows : J. D., aged 26, was admitted into the hospital in July 1850. The internal saphena vein of the left side was varicosed, and a varicocele also existed upon the same side. Both these affections commenced at the age of seventeen, and had increased to such an extent as to prevent the patient from pursuing his occupation. The internal sa- phena was varicosed from the internal malleolus to the point at which this vein passes through the aponeurotic orifice into the femoral vein. There were several tumors along the course of the vein, formed by its tortuosities. The varicocele was quite large, the testicle a little atrophied, and in the engorged epididymis was a tumor the size of a small nut. The operation was performed on the 21st of July. The patient being placed upon his back, the leg flexed and turned a little outwards, an incision was made over the saphena orifice and parallel with the course of the vein. The parts were carefully dissected until the fibrous band of the orifice could be distinctly felt. A grooved director was passed beneath the fibrous band of the ring, and an incision made upwards through the band. Considerable inflammation and a rupture of the vein ensued. The wound, however, was cicatrized the twentieth day. The patient left the hospital seven weeks after the operation, very much relieved, though not entirely cured. The tu- mors along the course of the vein had very much diminished and the varicocele entirely disappeared. — Southern Med. and Surg. Journal. SELECTIONS. 299 Of the Retained Testicle Extruded by Accident. BY DR. J. M. ARMSTRONG, BERLIN, OHIO. In the autumn of 1S42, I was called to see a gentleman who, the messenger informed me, was laboring under hernia. When I ar- rived, I found what I supposed to be, a case of inguinal hernia ; but upon further examination, I discovered that it was of a peculiar form and density. When upon still further examination, I discovered that one of his testicles had been retained from infancy, and that the sup- posed hernia was this testicle, which had passed through the inguinal ring. Upon a more particular investigation, and by comparing the supposed hernial tumor with the testicle in the scrotum, I found that they were exactly similar, and came to the conclusion, that the sup- posed hernia was in fact the retained testicle, that had been forced out of its abnornal resting place, by the effort the patient had made in attempting to raise a beef that he had slaughtered. I replaced it, or reduced it with little difficulty, after which, upon the introduction of my index finger, into the ring, which was large, I could feel the testicle pressing against the internal ring. This case, to me, was rather singular, never having read or heard of a case of the kind. Therefore I kept my eye on the patient for some time, and learned from him lately, that it never had escaped since, nor had an}Tthing like hernia appeared. But he stated to me, that whenever he attempts to lift heavy loads, he can feel the nut, as he calls it, pressed against the ring. Now, had this been a case of simple hernia, it would most proba- bly have returned again, for his occupation being that of a butcher, and being called upon to lift frequently, and the ring being large, her- nia would undoubtedly have taken place. The retained testicle ap- pears to act as a plug, in or against the ring, and prevents the escape of any of the abdominal contents. — Ohio Med. and Surg. Jour. Coroners. As the jurisdiction of these officers is almost entirely in matters strictly medical, it seems desirable that they should be physicians. There is but one case in which the coroner is called upon to perform duties of any other nature, and medical men are as competent as others to the performance of this. We do not, then, see why it is not wiser to appoint to these sometimes responsible posts men who, from their professional knowledge, are qualified to select the fittest men to make the necessary examinations of the body ; to direct properly a medico-legal investigation ; and to instruct the jury upon the compara- tive importance and bearing of different medical facts. As it is, these officers must either depend upon some entirely irresponsible friend at their elbow, or be at the mercy of any witness whose ignorance or in- terest should lead him away from the truth. At present, none of 300 SELECTIONS. these officers in our state are from the medical ranks. We would suggest that if they should be made elective by the people, the physi- cians of different districts should present the fittest man among them as their candidate. Still farther, we believe it is time that the profes- sion asserted their right to certain positions. When commissions are appointed for the examination of medical matters, whether it be as to the treatment of the insane, the sanitary condition of paupers or prison- ers, or the healthfulness of localities, physicians have a claim upon the appointing power, which courtesy, if nothing else, demands should be considered, and which, in justice to themselves, they are bound to urge. It is from neglect of this duty to themselves that they are so often compelled to take a second place, when in justice the first be- longs to them. — New Hump. Journal of Med. ITEMS. McFadden, the Philadelphia druggist, convicted of manslaughter in causing the death of a young woman by dispensing morphine through mistake, has been sentenced to three months' imprisonment in the penitentiary. There have been several cases of this sort reported in the journals of late, and they will continue until the laws are amended on this subject. The managers of the Savannah hospital have pre- sented a splendid piece of plate to Dr. Rd. D. Arnold, in testimony of their appreciation of his labors during a period of 15 years. The celebrated obstetrician, Francis C. Naegele, lately died at Heidelberg, in the 72d year of his age. A cotemporary says that another pair of Siamese ? twins has been born in Pennsylvania ! ! The statistics of the American medical schools published thus far, shew, for the past sessions, 3800 students, and they have graduated 1280 new doctors ! We learn that a medical journal is about to be esta- blished in Washington city, D. C. Dr. Andrew Smith has been ap- pointed to succeed Sir James McGrigor, as the head of the medical department of the British army. The concours for the chair of surgery of the faculty of medicine of Paris was still going on, by the last accounts. It is said M. Robert or Professor Buisson of Montpe- lier, will get it. The head surgeon of a French lunatic asylum has been condemned to 15 days' imprisonment for "causing the death of a patient by laudanum in a lavement." He was condemned upon the evidence of two veterinary surgeons, which was counter to the evi- dence of five of the most celebrated physicians ! ! The celebrated Boston surgeon, Dr. Warren, has been sojourning for several days in Richmond, on his way to the American medical association at Charleston. It is to be regretted that the Doctor's health is feeble, though he still retains that vigor of intellect which has rendered him pre-eminent in his profession. THE AND VIRGINIA MEDICAL GAZETTE. No. 6.] RICHMOND, JUNE 1851. [Vol. I. Remarks on Scarlet Fever. BY M. H. HOUSTON, M. D., OF WHEELING, VA. [Read before the Ohio County Medical Society.] The number of deaths caused by scarlet fever every season in most parts of the world, indicates it as a disease occupying the very front rank, in point of practical importance. In the United States it figures so largely in the annual bills of mortality, that if an aggregate estimate of all the deaths it causes, within a period of twenty years, were made and compared with the mortality caused by the epidemic which now makes the world to quake with fear, the latter disease would become, if not insignificant, at least of secondary importance. Whilst epidemic cholera, in its warfare upon the human family, car- ries off its thousands at a single charge, maintained only for a short time, scarlet fever consigns to the tomb its tens of thousands by an untiring and perpetual siege. The one does its work quickly, and sinks exhausted by the effort, whilst the other works more slowly, and acknowledging no respite, is almost an entire stranger to fatigue. A disease which commits such frightful ravages can scarcely claim too much of our attention. The great mortality of scarlatina results from two prominent causes, and whether the greater portion of it be due to the one or to the other, it would be very difficult if not impossible to determine. The one is, the necessary and inevitable fatality which results from the viru- lence of the disease, as it occurs in some individuals under certain circumstances — the other, the result of unsettled and empirical modes of practice, arising from the want of a proper understanding of its true pathology. To remedy the first may be considered an impossi- bility, whilst to correct the latter may fairly be considered within the range of professional observation and research. The object of the following remarks will be to establish some pa- thological facts of a general nature, which may serve as a foundation on which to, build a more uniform and rational system of practice. That no general principles have been laid down and established sufficient to guide us in the treatment of the disease under the various 33 302 HOUSTON ON SCARLET FEVER. modifications which it presents, must be evident to any one who will examine the productions of all those who have written on the subject. As far as my reading has extended, the systematic winters on scarlet fever have indulged in a few vague and general remarks on the dif- ferent varieties of the disease, together with some directions, equally vague and unsatisfactory, as to the treatment proper for these varie- ties, whilst those who have made it the subject of special attention through the pages of our periodical literature, have, without any excep- tion, had in view the enforcement of some specific modes of treat- ment, which in their own hands, have proved more than ordinarily successful. In no one of them is there to be found any prominent pathological consideration, or any broad general principle which may serve as a beacon to guide us in adapting our remedial means to all the different phases of the disease. Without some such controlling principle of practice it is impossible for us to treat such a disease as scarlet fever with the greatest possible success ; whilst with it, we may at least save ourselves from the imputation of having treated a disease more for its name than for any substantial indications which it presents. Scarlet fever is the result of a specific poison. Is this a proposi- tion which admits of any doubt ? To my mind it is clearly proved by the fact, that when an individual susceptible to its action is ex- posed to the influence of the poison, he has produced within him a train of morbid action, resulting in the development of certain ap- pearances to be found in no other disease, and without which it can- not be pronounced scarlatina. In other words, the development of the poison in the system produces an eruption on different parts of the body, presenting certain uniform, essential characteristics, and without such evidence of the existence of a specific poison as is fur- nished by this peculiar eruption, scarlet fever cannot be pronounced to exist. It may be said, however, that we have cases of scarlatina without any eruption on the skin, and that, too, in its very worst form. This is true; but in all such cases, the eruption will be found on the mucous membranes generally, and its non-appearance on the skin is owing to causes to which more particular allusion will be made hereafter. In no case do we fail to detect some appearances of the peculiar eruption on certain portions of the mucous membranes. Added to this, is the evidence furnished by our olfactories. The odour of the poison of scarlet fever is just as distinct, and in many instances quite as strong as that of the smallpox poison. It is no evidence against the existence of this specific poison to say that we know nothing of its essential properties. The same may be said with equal truth of all other animal poisons, and indeed, of all matter whatever, and yet, like other varieties of matter, we may know it by its properties ; and to the observation and investigation of these properties, our attention may be very profitably directed. The first ascertained property of the poison of scarlatina to be noticed is, that however introduced into the living system, it repro- duces itself whenever there exists that condition of the circulating fluids which favors its reproduction. In this respect, it is analogous HOUSTON ON SCARLET FEVER. 303 to the poison of smallpox, syphilis and other animal poisons, whose reproduction is brought about by inoculation. This is proved by the fact, that when an individual enjoying the susceptibility to scarlet fever is exposed to its contagion, a longer or shorter period elapses before its development is made manifest. This is the period of in- cubation of the poison. That such a period does exist, must be evident to any one who has observed the order of succession in which the disease occurs in large families of children. A single one is gene- rally seized in the first instance, and the symptoms do not display themselves in the remainder until six or eight days have elapsed, when they all fall sick about the same time. It does sometimes hap- pen that only a portion are taken sick at the end of the period men- tioned, whilst the attack is postponed in others until the end of another eight or ten days. This can be accounted for only on the supposition that the last of the family contracted the contagion, not from the first, but from those secondarily affected. The same thing sometimes hap- pen in smallpox. It does not militate against this view of the repro- ductive property of the scarlet fever poison, to admit that the disease does not always have its origin from direct contact with those affected. The poison does certainly exist in the atmosphere, in such quantities, at certain periods, as to impart an epidemic character to the disease. But does this prove that it does not possess the power of reproduction when introduced into the living system? Certainly not ; for if it did, it wrould equally prove the non-reproductive properties of the smallpox poison — a property which no one seems to doubt its possessing. A poi- son purely atmospheric in its origin may possess this property of re- production as certainly as one purely animal. The time during which this reproduction of the poison takes place in the human system, and the extent to which it is carried, are influ- enced by a variety of circumstances and conditions, all of which have their effect in modifying the symptoms and in increasing or diminish- ing the violence of the disease. It is modified by the quantity of the poison at first introduced into the system. With like conditions of the circulating fluids and other corresponding circumstances, the greater the amount of poison introduced, the more rapid will be the comple- tion of the reproductive process. We hence find that, other things being equal, those are most violently affected who contract the disease from breathing an atmosphere in which the poison has been accumu- lated and concentrated by numbers of the sick being crowded to- gether in ill-ventilated apartments. At least, such is the result of my own observation. Unless very special attention be paid to cleanliness and ventilation, the last cases occurring in large families are usually the worst. The condition of the blood itself exercises a modifying control over the reproductive process, supposing equal quantities of the poi- son to be introduced into systems unequally predisposed. It is well known that some persons manifest no susceptibility to the disease, however much they may be exposed to its contagion. This, however, is the exception to a general rule ; for it is equally well known, that a very large majority of all the human family are born with a suscepti- 304 HOUSTON ON SCARLET FEVER. bility to this disease, which susceptibility, once developed, is rarely reproduced. Some individuals, subjected to the same general influ- ences, and exposed to the same sources of contagion, under the same circumstances, will have the disease severely, others more mildly, whilst a very few will not suffer at all. This can only be explained upon the supposition that we are born with, or acquire during the early period of lactation, some peculiar principle of the blood, upon which this special poison is dependent for its reproduction. What this peculiar principle may be, it remains for future investigation to determine. It is sufficient for the present to know that it must exist — that in the reproduction of this poison it is destroyed — that it is very rarely regenerated, and that when so regenerated, it renews the sus- ceptibility to the disease. The extent to which the reproduction of the scarlet fever poison will be carried in any individual, must of necessity be mainly de- pendent on the amount of this principle which exists in the blood at the time of exposure to the contagion. This principle is the pabu- lum upon which the poison feeds. The destruction or consumption of this pabulum furnishes the limit to the quantum of the poison, and as a general rule the limit is always reached. The time occupied in the consumption of this pabulum varies un- der varying circumstances of temperature and individual constitution. We find the period during which scarlet fever develops itself vary- ing at different seasons of the year. During the spring months, the poison reproduces itself rapidly, and the disease runs its course more speedily than during the steady, cold weather of winter. Whether this be owing to the effect which an increase or decrease of tempera- ture has upon the reproductive process itself, or whether it be owing to the different conditions of the system found to prevail during these seasons, or whether to both of these causes combined, it is not our purpose to enquire. We know that the same disease assumes differ- ent types in the same individual, when occurring at different sea- sons of the year, and scarlet fever furnishes no exception to the gene- ral rule. Activity characterises the diseases of spring, whilst sloth is equally characteristic of those of dead winter, and we moderate the activity of the one by diminishing the heat, whilst we increase it in the other by an increase of warmth. The effect which difference of temperature has in modifying the disease, and the practical indica- tions furnished by these modifications, will be alluded to more particu- larly hereafter. From what has been said, it will readily be inferred that the ten- dency to a fatal result in scarlet fever may arise from several distinct circumstances, although the primary and efficient cause be always the same. The quantity of the poison at first introduced into the system may be large, and the condition for its propagation so bounti- fully supplied in the blood, that such an amount of poison will be generated as will necessarily prove destructive to life, under any cir- cumstances. These are the cases, fortunately of not very frequent occurrence, in which the patient dies as though he had been knocked on the head with a hammer. No remedies have any effect in arrest- HOUSTON On SCARLET FEVER. 305 ing the fatal result. Death is the necessary and inevitable conse- quence of a cause which we can neither avert or counteract. But death may result, even although the amount of poison in the system does not necessarily constitute a fatal dose — it may destroy life by the mere rapidity with which it is reproduced. We all know how the system will gradually accommodate itself to the action of morbid impressions of any kind, until it will at last bear, with com- parative impunity a dose, which, if given at first, would have speedily proved destructive. A confirmed drunkard will swallow as much alco- hol at a single draught, with the effect only of rendering him comfort- able, as would kill outright one of the sons of temperance. So with the poison of scarlatina. It may be reproduced so rapidly that the vital organs cannot accommodate themselves to its action, and death will result from the suddenness of the blow. Again, death may result from the slow and long protracted repro- duction of the poison, by which the vital organs are exposed to its continuous action so long, that their natural sensibility is exhausted and their functions hopelessly perverted. If the wine-bibber con- tinues his potations, he as certainly dies in the end as though he had taken a fatal dose of the poison in the beginning, and the same is true with regard to the action of the animal poisons. Death may also result from an unequal distribution of the poison, even when the whole amount in the system is not sufficient necessa- rily to produce such a result. An undue proportion being determined to the brain, for example, whilst other organs are in alike proportion relieved, will as certainly cause death, unless such determination be removed, as though all of the organs were oppressed with a fatal dose of the poison. The same remark will equally apply to all the other vital organs. In the last place, death may result from causes which interfere with those processes instituted by nature to throw off the effete poison after its reproduction has been completed and its active properties destroyed. These constitute the so called sequelae of the disease. Their true pathology, and the general principles which should guide us in their treatment, demand a separate and more extended con- sideration than the limits of this paper will admit. Bearing in mind the foregoing general propositions, which we con- ceive the phenomena of the disease warrant us in affirming, we have a clue to its varieties, as recognized by authors, and to the few broad principles which should govern us in its treatment. When the quan- tity of the poison introduced into the system is small, the pabulum for its reproduction in the blood limited, and the poison when repro- duced equally distributed through the system, we have presented to us the most simple variety of scarlet fever. When the quantity of the poison originally introduced is large, the pabulum for its repro- duction very abundant, and circumstances of all kinds existing to favor the reproduction,- we have presented to us the most malignant species of the disease — one of those cases in which the patient goes down to the grave suddenly and surely, in spite of the best directed efforts of the most skilful physician. When the poison is not repro- 306 HOUSTON ON SCARLET FEVER. duced to an excessive degree, but is unequally distributed, we have the several other varieties, as the anginose, the congestive, &c. Now it must be evident, that between the two extremes, we may have every variety of grade, and that the simple may be converted, by various circumstances, into the more malignant and fatal varieties, whilst some, that in the beginning have a fatal tendency, may, by judicious management, be converted into the milder forms. Thus, the amount of poison which in one individual, under the same circumstances, will, when equally distributed through the system, be productive of no very serious inconvenience, may, in another, when the larger por- tion of it is determined to a vital organ, prove very speedily fatal. These local determinations may be caused by constitutional pre- disposition, by varieties of temperature and different seasons of the year; or lastly, by the use of medicines injudiciously administered. In one individual, undue predominance of cerebral development will give rise to the comatose variety ; in another the scrofulous diathesis will lead to obstinate glandular enlargements, whilst special local af- fections of various kinds will result from special local predispositions. In the spring of the year, anginose affections are apt to prevail, and then we have an excess of the poison about the throat, giving rise to anginose variety. In the winter, when other diseases assume a low form, we find the reproductive process carried on slowly, giving rise to the typhoid variety, in the manner before explained, and so on of all the other varieties. The local determinations caused by the use, or rather by the abuse of medicines, will vary, as a matter of course, according to the medicine used. They constitute a very large por- tion of that numerous class of cases which prove fatal in spite of the most powerful medicines the doctor could prescribe. From the foregoing considerations we may deduce the following, as leading objects to be kept in view in the treatment of scarlet fever. First. To regulate, as far as may be practicable and desirable, the time during which the reproduction of the poison is carried on. Second. To secure by all the means at our command, the distribu- tion of the poison among the different organs in proportion to their ability to sustain themselves under its action, and Third. To promote the rapid and complete elimination of the poi- son from the system, after the process of reproduction is complete and the activity of the poison expended. Any theory of disease, in order to be true, must be sufficient to ac- count for all the phenomena which present themselves under every variety of circumstances. It has been stated before, that different writers on scarlet fever have extolled different and very opposite modes of treatment, and they all adduce cases to prove the success of their practice. The history of these cases cannot for a moment be doubted, nor is it necessary for the support of our views that they should be proved to be untrue, since they are all satisfactorily ac- counted for on the general principles already laid down. The error consists in recommending an exclusive plan of treatment for scarlet fever in general, which is alone applicable to distinct, and perhaps HOUSTON ON SCARLET FEVER. 307 very rare modifications of the disease. We find one writer recom- mending the application of cold, ice water as a specific, another the use of an increased amount of heat; one advises blood-letting, whilst another uses stimulants — one says, give large doses of calomel, with active cathartics, whilst another recommends the avoidance of mer- curials, and the cautious use of the most gentle laxatives — and they all adduce numerous examples of the success of their treatment. Now, it is unreasonable to suppose that any one of these exclusive methods of treatment would prove successful in those cases in which a directly opposite mode of treatment has been attended with fortu- nate results. We accordingly find, that when the remedies advised and extolled by one practitioner have been used by others under dif- ferent circumstances, the results have proved so destructive as to lead to their speedy abandonment. How, then, are we to account for the different results of treatment, in the same disease, upon the general principles of pathology already laid down? Are they suf- ficient to explain all these varying phenomena ? We most unhesita- ingly answer in the affirmative. Take, for example, those cases in which the free application of cold to the head and surface generally, was attended with the most salu- tary effects, and we constantly find the symptoms to have been all such as indicated an unusually rapid reproduction of the poison, with or without local determination to the head. Within a few hours after the first onset of disease, there were high fever, burning hot skin, and a sudden and copious eruption over the whole surface. These are the very circumstances, which, according to the general principles al- ready explained, would indicate the propriety and necessity of a re- duction of temperature. The poison has generated loo rapidly, and the very suddenness of the impression was such as to cause death, unless something had been done to moderate and prolong it. The vital organs, taken by surprise, would have yielded to an impression, which, with the advantage of a timely warning, they proved them- selves able to withstand. In this respect, the reproduction of the poison may be aptly compared to the ordinary process of fermenta- tion. The poison is the. leaven, the blood the pabulum, and the dif- ferent organs of the body the vessels which contain it. If you stir the materials together and place them in a warm situation, the pro- cess of fermentation or reproduction will prove so rapid as to break the vessels, unless free exit be given to the product. If the leaven, however, be not mixed with every part of the pabulum, and if the whole be placed in a cool situation, the process will take place slowly and without endangering the destruction of the containing vessels. In an analogous manner cold acts in retarding the reproduction of the poison of scarlatina, and it matters not, as far as the general princi- ple is concerned, whether it act by its depressing effects upon the nervous system, or whether upon the ordinary philosophical principle of a reduction of temperature. In all of the cases which I have ex- amined, the effect of the cold has been to protract the period dur- ing which the eruption made its appearance. The same illustration will apply to those cases in which warmth 308 HOUSTON ON SCARLET FEVER. has been found to benefit the patient, and in which too slow a repro- duction of the poison has tended to subject the organism to an impres- sion of the poison too long to prove consistent with a resumption of healthy function. The next general principle is one which applies with equal force to every variety of the disease. It is to secure as far as possible a distribution of the poison among the different organs of the body, just in proportion to their ability to sustain themselves without fatal injury, under morbid impressions of all kinds. This is the one grand princi- ple, an observance of which can alone lead to the most successful treatment of the whole family of eruptive diseases. Were we able in any given case to determine beforehand, that an amount of poison would be generated, which, when thus distributed, would be sufficient to cause death, we might, with a clear conscience, resign our patient to his fate, without inflicting on him the additional discomfort of nau- seous medication. As it is impossible, however, to determine, a priori, what amount of poison will be generated in any particular case, it becomes our duty to watch closely the development of the disease, and when we find fatal oppression of the vital organs impending, to use such means as are calculated to solicit from the more delicate, and determine to the less important organs. This can only be done by soothing the one at the same time that we irritate the other. We cannot cut short or cure the disease — all we can hope to do is, to conduct it to a safe termination ; and to administer medicine of any kind without some special, definite object in view, having reference to the general principle above laid down, would be as rash as to throw a firebrand into a magazine of gunpowder. We should play the owl and watch, but never strike until compelled by necessity. It has been said before, that the varieties of scarlet fever are due to certain local determinations of the poison. Although the general principle which guides us be still the same, yet the treatment of these varieties must be modified according to the particular determination. The same general principle will in fact lead to directly opposite and apparently inconsistent modes of treatment. The judicious practi- tioner must feel compelled to blow hot and cold upon disease bearing the same name whenever he finds it clothed in garments of unequal warmth. It may be said by the advocates of mere matter of fact narration, that all this is hypothesis, and therefore worthless. That it is, to a certain extent, hypothetical, I am free to admit, and yet if it leads to sound practical results, a quietus should be put to all such objections. The principles of our science are not subjects of mathematical de- monstration. To discard hypothesis entirely, would be to put an end to all reasoning upon medical subjects. When an hypothesis is as- sumed, and facts are presented to its support, harm must unquestion- ably be done, but when it is deduced from the facts, and proves suffi- cient to account for them all, and when it forms the basis of correct and determinate modes of treatment, it certainly can make but little difference whether it be true or false. Its adoption, under such cir- cumstances, can do no harm, and may do a great deal of good. HOUSTON ON SCARLET FEVER. 309 It might, perhaps, be sufficient for me to enumerate these general principles of treatment, and leave it to each individual to select his own means to fulfil particular indications ; but as there are some spe- cial points of practice to which I desire to direct particular attention, I shall apply them as concisely as possible to some of the varieties of the disease usually recognised by systematic writers. And first, of the mild or simple form of scarlet fever. In this variety of the disease, the poison generated is not excessive in quantity, and it is fairly distributed among the different organs. The best authors concur in saying, that the proper treatment consists in letting the dis- ease take its own course, without any, or if any, with very little medi- cation. They neglect, however, to impress upon the mind of the reader the important fact, that active medication of any kind will prove decidedly injurious, and that by improper interference, the mild may be converted into a very troublesome, not to say malignant and fatal form of the disease. This becomes the more necessary, since many persons are apt to think that the same remedies which cure a violent form of disease, will, a fortiori, and with much greater certainty, cure a milder form. They forget, or entirely lose sight of the principle, that in this disease medicines act by relieving one local determination at the expense of producing another, and that in the use of active agents of any kind, it always becomes a mere choice be- tween two evils. Hence, in any given case, when no local determi- nations exist, active remedies produce them, and thus convert a simple and mild form of disease into one complicated and malig- nant. It is to the importance of avoiding all rash interference in cases of this kind that I wish to direct particular attention. It may be thought by some, that under such circumstances, no sane man would ever dream of adopting any active treatment ; but in this they are mistaken. The very name of scarlet fever strikes terror into the minds of patient as well as practitioner, and it requires some expe- rience, as well as some firmness of purpose, to stand with folded arms, in the presence of a disease known to be attended with such danger, and that, too, when all around are disposed to think that so powerful an enemy can only be successfully combatted by very powerful wea- pons. The truth of this remark, as well as the evils resulting from such rash interference, will be best illustrated by referring to a few cases, selected from persons not treated by any member of this association. A girl aged twelve or thirteen years, of good constitution and robust general health, was taken with the ordinary symptoms of scarlet fe- ver some time in the spring of 1836. On the second or third day of the fever, the eruption began to make its appearance on the surface, and a physician was sent for, who pronounced it scarlet fever, and at once commenced his " scarlet fever treatment." At this time the pa- tient complained of no extraordinary discomfort. There was some soreness of the throat, with moderate thirst and heat of surface, but no hcadach — no pain in any part of the body, and nothing that I could discover from the most careful enquiry demanding any active interference. The patient, however, was bled in the morning, and 34 310 HOUSTON ON SCARLET FEVER. took some closes of cremor tartar and jalap, at intervals during the day. The eruption was sufficiently copious on every part of the skin, and of a florid, healthy color. The medicine operated moderately on the bowels, and the case seemed to progress favorably in every re- spect until the evening, when the patient was again bled, and the purgative repeated. In two hours after the bleeding, the medicine operated copiously, the eruption left the skin, the face became pale, violent convulsions set in, and the child died at two o'clock in the morning. I saw it a short time before death, and obtained the above history from the attending physician and from the child's father. Now, in this case death was certainly due, in the end, to the action of the poison on the brain and nervous system ; but why did it act so powerfully on these organs ? To what cause was the death to be legitimately attributed ? To my mind there is no doubt but that it was caused by the uncalled-for and injudicious use of remedies. The direct effect of venesection is to impair the strength of the vital powers, and to render the nervous s)'stem, particularly, more impressible by morbid agents. The force of the heart and arteries being reduced by the loss of blood, and by copious serous evacuations, they failed to circulate the blood in the extreme vessels ; hence an accumulation of the poison in the vital organs, by the same cause which rendered them less able to sustain themselves under its impression. Convul- sions and death were the consequences which might have been antici- pated from such a course of treatment under such circumstances. Three other cases occurred in the same family, admitted to have been of equal severity in the commencement, and yet they all re- covered without the employment of any active treatment whatever, and without the occurrence of a single unfavorable symptom. It may be asserted with safety, that in the simple form of scarlet fever at least blood-letting is never required, and that it cannot be practised without great danger. In many other diseases, even where not clearly indicated, it may be practised without any very serious injury, but here it is capable of producing the most deadly effects. When the poison is already equally distributed, it can have no effect in maintaining that equal distribution, but it may be the means of in- ducing fatal accumulations in vital organs. Are purgatives proper in this form of the disease, and if so, what kind ought to be used, and under what circumstances are they indi- cated ? As a general rule, the impression of the poison on the mu- cous membrane of the stomach and bowels is such as to exalt their sensibility, or rather to induce such a state of irritability as leads to vomiting or purging, or both together. Under such circumstances, cathartics of any kind would not be proper, but more especially would irritating cathartics be contra-indicated. Their effect would be to in- crease the evil which they were intended to remedy, and yet how often do we find them used under precisely such circumstances? Their effect must be to determine still more of the poison to the bowels, and thus induce a state of the mucous membrane, which days and even weeks of the most careful management will, in many cases, scarcely prove adequate to remove. HOUSTON ON SCARLET FEVER. 311 Upon the general principle already laid down, the proper treatment of such cases consists in soothing the stomach and bowels by the use of mild opiates, with the free use of mucilaginous drinks, and in de- termining to the surface, by gentle diaphoretics, the tepid or warm bath, and stimulating embrocations to those portions of the skin on which the eruption is least abundant. The poison is thus drawn off from the more important and directed to the less vital organs. The circumstances under which purgatives are demanded in this form of the disease are, when there are costiveness of the bowels, with little or no redness of the tongue, indications of undue determi- nation to the head, and such determination of the poison to the skin itself as may endanger life ; for it must be borne in mind, that an amount of the* poison may be determined to the skin sufficient to de- stroy life independent of its direct action on other organs. A very memorable example of this kind occurred to me in the spring of 1837. A lady, the head of a large family, was seized with scarlet fever, which prevailed epidemically at the time. The eruption came out more copiously than I ever saw it in any case either before or since. The evidences of the poison in other parts of the system were much less than usual. The tongue retained its natural color ; there was no soreness of the throat, the stomach and bowels were un- affected, and nothing remarkable presented itself except the intense scarlet rash on every portion of the surface. Desquamation com- menced at the usual period, and continued during several days to such an extent, that when the patient walked across the floor, as she was able to do at this time, her track was as though a bran bag had been shaken over the carpet. The functions of the skin were en- tirely suspended during so long a period that congestion of the inter- nal organs supervened as a consequence, and death took place at the end of eight or ten days. The patient obstinately refused all. medi- cines during the whole course of her disease. A burn covering the whole surface could scarcely have proved more certainly fatal. Nothing but the free application of cold to the surface during the stage of eruption, with active purgation, could have afforded her any chance of relief, and to these she would not submit. Under all circumstances the action of purgatives should be very care- fully watched, and their use discontinued whenever we find the tongue becoming red and dry, and the operations frequent, watery and irri- tating. When they do become necessary, what kind of cathartics ought to be used in the simple form of scarlet fever? This will of course de- pend upon the particular indication which they are intended to fulfil. We have before remarked, that as a general rule they are not required at all ; but when they are indicated by a simple costive state of the bowels, without local determinations to important organs,, the mildest and least irritating should be selected and given in such doses as merely to open the howels. It is surprising how small a dose of the mildest purgative will sometimes operate more powerfully than we either anticipate or desire. We have known a single teaspoonful of castor oil to produce hypercatharsis in an adult patient when given 312 HOUSTON ON SCARLET FEVER. during the stage of the active reproduction of the poison, and the same may be said of other cathartics. Small doses of oil, a Seidlitz powder, or small portions of Epsom salts will, in general, answer the purpose very well. Calcined magnesia, from its insolubility and its consequent irritating effects on the mucous membranes, is for the most part an unsafe purgative. Are the different preparations of mercury, when used either as al- teratives or purgatives, proper during the active stages of scarlet fever ? This is a very important question. And as all writers recommend without much qualification, and nearly all practitioners use mercu- rials to a greater or less extent in the early stages of the disease, I shall offer no apology for attempting to expose what I believe to be an improper practice. Viewed merely as a purgative, calomel, in addition to the irritating effects common to it with other cathartics, has the additional effect of exciting the liver and other secreting organs opening into the alimen- tary canal into increased activity, by which acrid secretions are brought into immediate contact with mucous membranes already in a state of morbid excitability. They are thus subjected to the mor- bid impression, not only of an increased amount of the poison itself, thus invited through the blood-vessels, but likewise to the injurious impression of a host of vitiated secretions. Under their combined action the tongue becomes dry, red and disposed to ulceration, whilst the operations become thin, frequent and acrid, as the excoriations about the rectum will generally testify. If persevered in, these symptoms are all aggravated, the skin becomes dry, the pulse becomes full and frequent, sordes collect about the mouth, and in the end the patient dies, either from haemorrhage, or at a later period, from ulceration of the mucous membrane of the stomach and bowels. This is no pic- ture of the imagination. I have witnessed such cases, and I could attribute the result to no other cause than the blind and persevering use of mercurial cathartics. But what are the effects of mercurials when used as alteratives as well as cathartics ? You may combine them with opiates and thus prevent their free action on the bowels, but at the same time they are not without their injurious effects on the mucous membranes, whilst the}' are producing other effects not less troublesome and oftentimes fatal. It is known to all that mercury is rapidly taken up by the ab- sorbents, and that in this way its constitutional effects are produced. When thus absorbed it may act beneficially in one of two wa}7s, either by destroying some poison with which it meets in the blood, thus becoming its antidote, as in syphilis ; or by substituting its own for some other morbid action not necessarily persistent in the system, as in inflammation. Now, experience has taught us that it is not an an- tidote to the poison of scarlet fever, and therefore it cannot prove use- ful in this respect ; neither can it substitute its own for the action of the other poison, since the latter continues to exert its influence as long as the reproductive process continues. Hence by its introduction into its circulation, the organism is subjected to two poisonous impressions instead of one. HOUSTON ON SCARLET FEVER. 313 But mercury is known to have a predilection for some particular organs, and in stimulating these it necessarily carries with it a larger amount of the scarlet fever poison : hence an excess in the glandu- lar system generally, but more especially in the lymphatic glands. It is this abuse of mercury in scarlet fever which in many instances gives rise to those glandular enlargements, inflammations and ulcer- ations which we so often meet with among the number of its sequelae. The predilection which mercury has for the salivary glands and the organs about the throat is well known, and hence the extensive ulce- ration and sloughing of the tonsils met with in the anginose variety of the disease, when its salts have been used even in moderation. It will be borne in mind that I am now speaking of the use of mer- curials at any time during the stage of reproduction of the poison ; their use during the latter stages of the disease involves considera- tions of a nature altogether different. The following narration may serve in some measure to illustrate the truth of these remarks. Some ten or twelve years ago scarlet fever prevailed as an epi- demic in Burlington, a village at that time containing not more than one or two hundred inhabitants. Whilst on a visit to a patient in the neighborhood, I was met by a gentleman of the place, who told me that some eighteen or twenty cases had occurred, and that out of the whole number not a single one had recovered. From more particu- lar enquiry, made as well at the time as subsequently of other indi- viduals, I ascertained that it was the anginose variety of the disease which prevailed, and that all the cases were treated actively during the early stages with emetics, calomel and stimulating gargles, and particularly that calomel in large or small doses, or both, had never been omitted. I also learned that the patients had died with mortification of the throat, and evidences of much disease in the ali- mentary canal — that the eruption, although sufficiently florid and co- pious at first, would not stay out, and that all the strong medicines the doctors could give seemed to have no effect on the disease. He also told me that his own children, four in number, were then taking the disease, and that he had determined not to send for any physician, but to consult me and be governed by my advice. The only thing he had given them was onion juice. Taking advantage of his preju- dice in its favor, I advised him to give them no other medicine ; but if the throat became very sore, with much accumulation of viscid mucous, to give it in such quantities as to vomit gently, and then omit it entirely. I also advised him to let them have no cold drinks, and to use tepid slippery elm or flax seed tea for a gargle. On the de- cline of the disease he was recommended to use the warm bath daily, and if the bowels were costive and the kidneys at all inactive, to give a teaspoonful of Epsom salts, with a few grs. of nitr. potass, every morning for several days. With these directions he left me, with a promise to call again if anything unfavorable should occur. Four weeks afterwards he informed me that every member of his family had recovered under this simple treatment, without a single unfavor- able symptom. From these facts it is certainly not unreasonable to draw the con- 314 HOUSTON ON SCARLET FEVER. elusion, that in some of the fatal cases, at least, death did not result from the whole amount of the poison in the system being too great to prove compatible with life, but from the fact that so great an excess of it was determined to the throat and alimentary canal by the reme- dies used as to destroy their vitality. They were cases of the simple, converted into the malignant anginose variety. As a general rule, then, it may be asserted that the preparations of mercury are not only not demanded, but that their use is apt to prove highly injurious in the simple forms of scarlet fever. This danger is increased or diminished just in proportion as the whole amount of poison in the system is greater or less in any particular case. Without discussing further the effects of particular remedies or the influence of other specific modes of treatment, it may be stated in general terms, that the proper mode of treating the simple form of the disease under the general rule laid down, consists in watching closely the progress of events and in not interfering in any way, unless local determinations are impending ; and where these do occur, they are to be corrected by soothing applications on the one hand, and derivatives on the other. A comfortable temperature — warm lemonade or warm slippery elm tea, acidulated with lime juice, for drink — an occasional teaspoonful of castor oil when the bowels are costive, a mild, unirrita- ting diet, and the daily use of the warm bath on the decline of the dis- ease, are generally all that becomes necessary. Local determination to the throat, constituting the anginose variety, demands some special notice. It is manifest that this may be either mild or malignant, in proportion to the relative amount of the poison directed to the throat as well as in proportion to the whole amount in the system. Whilst the first class of cases may generally be consi- dered manageable, the latter are often necessarily fatal. We may procure a more equable distribution of the poison, but we cannot con- trol the whole amount in the system. The same general principle of treatment, however, will apply to both. Whatever may be their modus operandi, emetics certainly have the effect of lessening the determination of blood to the throat. Unless its use is specially contra-indicated, a mild emetic will, therefore, ge- nerally be proper in the commencement of the disease. Should the bowels be costive, it may be followed by a small dose of castor oil. Magnesia, on account of its rough action on the mucous membranes, should be avoided. The stomach and bowels should then be left in quietude. In the mean time the integument of the throat and upper part of the chest should be rubbed with a stimulating liniment and kept moderately warm. The liniment should also be applied to the whole surface of the body, but particularly to those parts where there is the least appearance of eruption. No cold drink should be allowed to the patient. If cold could be constant^ applied to the throat in the form of cold drinks or small lumps of ice, it might prove useful; but as it is generally used, reaction takes place in the intervals and the inflammation is increased. When the tonsils are much enlarged and the general tumefaction great, local depletion by scarifactions will become proper; but, if possible, it is best to avoid them, as they are HOUSTON ON SCARLET FEVER. 315 liable to be followed by troublesome ulcerations. All stimulating and irritating gargles should be studiously avoided. The mildest are the best, and I know of none better than the slippery elm or flaxseed tea, acidulated, when there is much mucosity, with lime juice or vinegar. The local practice should consist in soothing the throat, whilst the skin and other organs, in which there is a less amount of the poison, are being constantly and uniformly stimulated. The limits of this paper, already transcended, will not allow me to allude to much less to dwell on the different points of practice that are of great importance in the management of this disease in all its varieties. On the form with cerebral determination, however, I feel constrained to make a single remark, as it calls for a class of reme- dies which prove injurious in most of the other forms. In the malig- nant variety, with determination to the head, the danger is always imminent, and death must result unless the nervous system be spee- dily relieved. We are then compelled to choose the least, it may be, of two great evils. We must relieve the head at the risk of destroy- ing the functions of other organs, not so immediately required in sus- taining life. Calomel in large doses, from its known power to relieve congestion of the brain, as well as from its effects on other organs, must be resorted to at once. Large doses are preferable to small, because the sedative effect is more prompt and decided, and because, from its action as a cathartic, it is less liable to be absorbed and thus produce its injurious constitutional effects. Ten grains, repeated at intervals of six hours, each close to be followed by a dose of castor oil, is the plan which, in my hands, has proved the most successful. At the same time, cold should be applied to the head, whilst the pa- tient is put in a warm bath ; and this should be succeeded by fre- quent stimulating pediluvias and turpentine embrocations to every part of the surface. Even here it is necessary to keep a close watch lest we attract more of the poison to the stomach and bowels than they are able to bear. As soon, therefore, as we find the tongue becoming redder, and indications of a free and more permanent eruption on the skin, with corresponding evidences of relief to the brain, our active measures should be relaxed, and our attention directed to palliating the effects of our remedies. At the best, if the head be relieved, we will have a long and troublesome course of soothing treatment to pur- sue before the stomach and bowels will resume their healthy tone. This is the form of scarlet fever in which blood-letting has been practised and so highly recommended. In all cases of the disease, the state of the pulse, as an indication of fever, is strangely dispropor- tioned to the other symptoms; and although I do not deny its utility, yet, I must confess, with the frequent, feeble pulse that I have alwaj^s met with in this form of the disease, I have never thought it safe to venture on the use of the lancet. The only stage of the disease in which I have resorted to blood-letting, is after the process of repro- duction is complete, and nature fails in her effort to throw off the effete poison. To accomplish this, inflammatory action is lit up, and unless controlled by suitable remedies, it terminates either in local in- flammation or general drops}'. Under these circumstances the lancet, 316 HOUSTON ON SCARLET FEVER. and calomel in small and frequently repeated doses, become the an- chors of our hope, and I know of no disease in which the effects of our remedies prove more generally satisfactory. The typhoid variety, or the winter form of scarlet fever, requires a long course of close watching, with very little medication. We must look out for local determinations, and as far as possible counteract them when they occur. Of course we must carefully avoid all sources of irritation, and be on our guard for a much longer period than in the other varieties of the disease. There is one simple point of practical importance common to this, with every other variety of the disease, to which I must merely allude; it is the state of the kidneys. If we can succeed in keeping up a free action of these organs, our patients will generally get well. It is more particularly important that their functions should be main- tained during the decline of the disease, as it is through them and the skin that the poison must for the most part be eliminated. For this purpose, the warm bath and an occasional dose of spts. nitr. dulc. will generally prove useful after the third or fourth day of the eruption. Passing over the whole of the sequelae, which involve topics quite as numerous and of equal importance with the disease itself, I shall close with a single suggestion on the subject of prophylaxis. We have stated in the commencement of our remarks, that scarlet fever depends for its development on the existence in the blood of some peculiar principle not yet ascertained, on which the poison pro- bably depends for it sreproduction, and that this principle, when once destroyed, is never, or but very rarely reproduced. The first step, then, towards a true prophylaxis, supposing it to exist, should be to ascertain what this principle is, and the next, to find some substance which, when introduced into the circulation, will have the effect of destroying it. It happens very singularly* that belladonna, the only article which enjoys the reputation of being a specific prophylactic, is extensively used by some brewers to modify the process of fermenta- tion. May it not combine with and destroy that peculiar principle in the blood on which the poison of scarlet fever depends for its reproduc- tion? If some competent person having charge of a scarlet fever hospital were to institute a series of experiments on the blood previous to the occurrence of the disease and subsequent to complete recovery, might it not be possible to detect this principle? With the accuracy of mo- dern chemistry in conducting minute analyses such a result might be fairly anticipated. Once discovered, it would prove an easy task to ascertain its antidote, and in this age of wonders it may yet happen that some of us will live to see the day when as thorough and as cer- tain a protection will be afforded, not only against scarlet fever but against all other eruptive fevers, as we now enjoy against smallpox by the practice of vaccination. Note. — Since writing the above I have had an opportunity of wit- nessing the effects of the anti-Hebraic treatment introduced and so highly recommended by Dr. Schneeman. Three children labored under the typhoid anginose variety of the GARDEN ON CIMICIFUGA IN PHTHISIS AND CHOREA. 317 disease. The inunction with bacon rinds had been sedulously em- ployed from the commencement of the disease. One child was dying, and the other bid fair to follow in its footsteps. Strong turpentine liniment was substituted for the grease, and they slowly recovered. My impression is, that if the friction be used, the lard may be omit- ted without disadvantage. Observations on the Remedial Powers of the Cimicifuga Ra- cemosa in the Treatment of Incipient Phthisis and Chorea. BY DR. THOS. J. GARDEN OP WYLLIESBURG, CHARLOTTE CO., VA. I promised on a former occasion a detailed report of some cases of incipient phthisis successfully treated with cimicifuga. Before doing so, however, it may be well to disseminate anew some observations relative to this article, published by me in the Medical Recorder as far back as the j^ear 1823. This paper is, I find, in the hands of a very limited number of physicians of the present day, and a consider- able time elapses always before a discovery or any important informa- tion on a novel subject finds it way into the text books of the schools ; for, according to my experience, the man who subscribes to and reads a well and ably conducted medical periodical, is invariably in ad- vance, on many practical points, of the literature of the schools and text books some ten or twelve years. The cimicifuga has now advanced to the first rank among the indi- genous articles of the dispensatory ; and although it has been before the public for near thirty years, and numerous tests of its powers and virtues in various forms of disease have been made by accurate ob- servers and faithful reporters, as well as numerous references to my paper in 1823, and since in Dungleson's new remedies, subsequent numbers of the Recorder and Journal, Gregory's and Wood's Prac- tice, still I fine some physicians and graduates in medicine are as ignorant of all that has been written and published upon the subject as those without the profession ; indeed I may say more so. All this must be the offspring of neglect, or something else, in not subscribing to periodicals. To my view they constitute a common centre or point whence our most valuable practical knowledge is radiated and re- flected. Up to the time of my first publication in the October Number of the Medical Recorder in 1823, page 609, the only account of this plant was to be found in Barton's collection of the indigenous articles of the United States, classed under the head of astringents. The popular name is rich weed, by which it is readily recognized by a number of planters, farmers and old women of our country, but as it may now be procured from any well regulated apothecary shop, neatly put up in a good state of preservation, any further description is superfluous. For the information of the curious, its botanical characters can be seen by consulting the Florida Cestrica of Doctor Darlington. As I enter- tain the same views I did thirty years ago relative to its therapeutic action and effects upon the human system, I have transcribed the 35 318 GARDEN ON CIMICIFUGA IN PHTHISIS AND CHOREA. language used by me in the publication referred to : " Like the digi- talis, it disorders the sensorium, and operates in a powerful manner upon the secreting and absorbent systems. When exhibited in a full dose it prostrates in a distressing degree, producing nausea, vertigo, pains of the extremities, anxiety, dilatation of the pupil, quick, small pulse, with universal restlessness and uneasiness. These effects are immediate and transitory. Its ultimate and remote operation is the converse of the above. It is this which gives it the supremacy over all other medicines of the same class. The digitalis induces a re- duction of arterial action at too great an expense of the general pow- ers of the system to be applicable to those cases wherein this medi- cine seems to be so admirably calculated to be productive of benefit. It is a paradox in medicine, and in whatever way it may be expe- rienced it certainly possesses the power in an eminent degree of lessen- ing arterial action, and at the same time imparting tone and energy to the general system. This, like many other phenomena relating to the science of medicine, will for some time to come be clouded in doubt and obscurity." In a publication by Charles C. Hildreth, M. D., of Zanesville, Ohio, on the same subject, in the October Number of the American Journal 1842, in a few remarks on the general character of the ci- micifuga, he uses the following language, shewing a coincidence of opinion, when it is manifest, too, he had never seen my first publica- tion, as at the onset he confesses his ignorance as " to whom we are indebted for the original introduction to the notice of the profession of the black snake root in phthisis." " That it has narcotic properties, somewhat similar to those of col- chicum, veratrum album or digitalis, we cannot for a moment doubt, after observing its influence on the brain, stomach, vascular and ner- vous systems. Thus a large dose of the strong decoction or tincture will produce vertigo and impaired vision, nausea and vomiting, re- duce the action of the heart and arteries, and induce perspiration." My principal object in making the above quotation from Dr. Hil- dreth's paper is, that the medicinal qualities of the cohosh may be more accurately defined, for while some ascribe to it narcotic pro- perties, others consider it a slight tonic. As before stated, it combines in its action both a narcotic and tonic property, and while the former prostrates so powerfully, it is by no means a dangerous narcotic. I once knew a confirmed drunkard, who was in the habit of begging for the tinctures in the shop, take two ounces of the strong tincture at a dose. It prostrated him completely, and he lay in the street until he was taken to his lodgings. He complained of slight headach next day, but his appetite was ravenous. Whiskey is a very good antidote to an over dose. Tonics, as Dr. Paris has justly remarked, are but relative in their operation. Debility in general is the result of organic or functional disease, and therefore not demanding the use of tonics for its remo- val. Strychnia in minute doses will display tonic powers, by stimu- lating the spinal or excito-motory system of nerves. The action of the cohosh on the nervous system is very obvious in chorea, of which I shall give some further illustration in the sequel. GARDEN ON CIMICIFUGA IN PHTHISIS AND CHOREA. 319 My first experiments with the cohosh in phthisis were made in 1819, upon the bare testimony of vulgar report, on my own person. At that time it was confidently expected by my friends, as well as a number of distinguished physicians, some of whom had examined me criti- cally, that I could survive but a few weeks at best. As the physical signs from auscultation and percussion were imperfectly understood at that time, it is probable the real nature of my own case was over- looked, and that instead of tubercles, softened down and excavated, it was what would now be diagnosed vesicular bronchitis. Be this as it may, I was promptly and permanently restored, mainly by the use of this article, to the enjoyment of comfortable health, and have per- formed the labors and encountered the exposures incident to a lucra- tive practice for thirty years since, after all other resources had failed to give even temporary relief from suffering. Suffice it to say, I had all the symptoms of phthisis of the most rapidly exhausting charac- ter. In a letter addressed to me by Professor Dudley of the Tran- sylvania University, Kentucky, in reply to one which informed him of my recovery, he uses the following emphatic language : "Your reco- very is a signal triumph over disease." In the case of J. F., reported in my paper in 1823, no doubt was entertained by myself or Dr. James May, formerly of Christiansville, now of Petersburg, as to its being a case of tubercular softening, the whole family, several brothers and sisters having died of phthisis, about the age of puberty. Under the use of the tincture of cimici- fuga, the form used by me at that time, in the space of between two and three weeks this man was restored from a state of perfect debi- lity and helplessness in bed so as to be able to walk about the yards and garden and take exercise in a carriage. Here the action of tu- bercle was evidently suspended, as the individual lived two years af- terwards, free from cough, and died finally of scrofula of his bowels, having rode as deputy sheriff part of this time. The more readily to make ourselves understood, two cases will be reported as having occurred within the last two or three years, but as I do not profess to be familiar with auscultation, the cases may be wanting in precision, and I shall of course not be able to give a satis- factory account of the pathological state of the lungs of my patients, and on this account, to some my communication may lose much of the interest that might otherwise be imparted to it. Case. 1. — This lady, Mrs. B., setat. 35, when first seen by us, had that train of constitutional symptoms induced bv the presence of tu- bercle or induration in the upper lobes, which even the common ob- server will justly pronounce consumption. She had for some years previously resided in a section of country proverbial for its fruitfulness in the production of bilious remittent and intermittent fevers, and had herself been the victim of repeated attacks. Her constitution had sustained a considerable shock from the conjoint action of disease and some of the effects incidental to remedies. At this time her con- finement to bed had been of about two weeks duration. Her pulse was rapid, skin hot, tongue foul, respiration embarrassed, cough trou- blesome and expectoration copious, of a muco-purulent fluid. As 320 GARDEN ON CIMICIFUGA IN PHTHISIS AND CHOREA. pneumonia bliosa was endemic in the neighborhood at the time, for the want of something better at hand, I left her some powders con- taining fractional portions of cal. t. emet. nitre and ipecacuanha, to be used pro ra nata. Finding no amendment under this treatment, I di- rected free pustulation over the diseased lobes with t. emet., and I pre- pared for her a strong decoction of cohosh from the root, with a com- bination of 6 grs. of tartar emetic and 1 gr. of acetate morphia to the pint of the decoction. Of this combination she was directed to take one tablespoonful every hour through the day, and as much of the decoction in a separate state as the stomach would bear without vomiting. With a view to regulate the biliary secretion, which was defective, I gave her 6 grs. of blue mass as an alterative cathartic every other night, and to quiet cough and diminish expectoration, a powder containing 5 grs. of acetat. plumbi. and 3 grs. pulv. Doveri every night. This plan, with some slight modification, was pursued for the space of about 10 days, when her amendment was apparent to all. The pustulation was directed to be continued, and as all the dis- tressing and urgent symptoms in her case had vanished, she was di- rected to take, which I prepared for her, 8 drops of the sol. of iodine and hydriod. potass., three times a day in a strong decoction of cohosh, until her natural respiration was restored, appetite and strength had returned and cough relieved. The sol. of iodine and hydriod. potass. was prepared with 10 grs. of the former and 20 grs. of the latter to the ounce of water. In a short time this lady, under the above treat- ment, was restored to her usual health, which continues permanent. This case occurred in the latter part of the winter 1S49, now two years since. I must acknowledge my indebtedness to Dr. Hildreth for this par- ticular mode of using the cimicifuga, since I deem it preferable to the tincture, the mode formerly used by me. It more readily throws off febrile heat and allays irritation. Case 2d. — This case occurred in the spring of 1850, just 12 months ago — a colored man, gel at. between 30 and 40, wheelwright by trade, of scrofulous family, and addicted to the intemperate use of intoxi- cating drinks. The physical signs in this case, when seen by me some three or four weeks after his confinement, caused me to diagnose a disorganizing process of the lungs, which would speedily result fa- tally. His pulse was steadily at 130 to 140 per minute ; on sitting up in bed, soft and compressible ; skin hot ; cough troublesome ; breathing difficult and hurried ; copious night sweats, &c, throwing up profusely mucous and muco-purulent expectoration. Viewing the case as almost absolutely fatal, I unhesitatingly prognosticated speedy dissolution. The cohosh occurred to me as the only remedy deserving a trial, or that promised even to palliate the symptoms in his case, and was resorted to more with a view to render his situation comparatively comfortable than any well-grounded expectation of a cure. Pustulation, with tartar emet. over the entire chest, was directed, but especially over the left lobe of the lungs, as there was consider- able dulness on percussion under the left clavicle. The poisonous ef- fects of the tartar were well developed in three or four days, causing GARDEN ON CIMICIFUGA IN PHTHISIS AND CHOREA. 321 a slough that extended from axilla to axilla, and yielding a most co- pious and salutary discharge. He was directed to take every hour through the day one tablespoonful of a strong decoction of cohosh, combined, as in the former case, with six grains of tartar and one grain of morphine to the pint, and as much of the decoction in a sepa- rate state in the intervals as his stomach would bear, and when the secretion into the bronchial tubes was excessive, to increase the dose until vomiting was produced. Blue mass in six grain doses was given every other night, and the lead and Dover's powder every night. The same general plan of treatment was pursued in this case as in the last. At the expiration of ten days the pulse had come down to near the natural standard, the cough much better and the febrile symptoms nearly disappeared. His recovery was rapid and uninterrupted. The iodine and cimicifuga in decoction were continued as long as his breathing was hurried on slight exertion. He is now (March 27th 1851) perfectly free from pulmonary disease and in robust health. The pages of the American Journal bear ample testimony to the power of this remedy in various forms of cough in the Western and Northern states ; and that whenever it has been wielded by a skilful hand — one who knew when and how to to control and modify its ac- tion by combination or other circumstances — I find it has always been used with good effects. Like all other remedies, this may be the pro- per one, yet it may fail for want of tact, not skill, in its administra- tion. The powers of this remedy do not end here, but are displayed more happily and promptly in chorea than in incipient phthisis. This wide range may alarm the incredulity of some, but well authenticated facts are worth all the reasonings of the theorist and the visions of scholastic philosophy. I know the power of habit and the prejudices of an early education, and the tenacity with which early imbibed opi- nions, however untenable, cling to the mind and effectually preclude the most palpable evidence. I once treated a case of chorea successfully by means of this re- medy alone, in a little boy nine years old, after the usual and most approved remedies had been previously perseveringly and diligently used for some weeks without the least effect. It was given in form of powder in teaspoonful doses morning and evening in a little molasses. Its effects were prompt and decisive. Its administration in this form of disease had not been thought of by me until my attention had been awakened by a publication in the Medical Journal, No. XVIII. Feb'ry 1S32, page 310, by Dr. Jesse Young of Chester county, Pennsylvania. He, like m}7sclf, was induced to use it upon vulgar report. Some old woman put him in possession of the remedy. In the sequel, in a note by the editor, he states he had been informed by Dr. Physic nearly ten years previous, that he had known that plant, given in doses of ten grains every two hours, prove successful in the treatment of chorea in several instances. In this disease the cimicifuga no doubt cures by an immediate and direct impression upon the nervous system. Eight or ten years ago, meeting with Dr. Wooton of Pleasant Grove, Lunenburg, quite an intelligent and sprightly physician, he informed 322 snead's case of mumps. me he had at that time a patient with chorea, a very interesting little girl about nine or ten years old ; that the girl bad been under his care about two months, and he had failed to afford her any relief. I sug- gested to the doctor the use of the cohosh in her case, and upon his consenting, and expressing a strong desire to give it a trial, I requested he would write me the result, as I was collecting some statistics for publication upon that subject. Three weeks afterwards I received a letter from Dr. Wooton, informing me of his patient's entire recovery, the fifth powder having arrested the entire catenation of morbid ac- tion, and up to that time there had been no return of her disease. In June 1849 I was requested to visit a patient with chorea, then under the care of Dr. Giles Harris, a popular practitioner of this county. It occurred in a girl about 12 or 13 years old, and proved to be a very intense and aggravated form of the affection. This case had been treated by purgatives and ol. terebinth., under the impression that verminous irritation had occasioned the disease. The cohosh in teaspoonful doses was now used for a short time, which entirely changed the character of the disease, causing it to take on periodical action, occurring about the same hour of the day, and shifting its seat from the muscles of the extremities to the chest and respiratory organs, im- parting to the breathing a peculiar convulsive and distressing moan or whine. A few more doses of the powder obliterated all traces of the affection. When subjected to analysis the cimicifuga is found to contain gum, starch, sugar, resin, wax, fatty matter, tannin and gallic acid, a black coloring matter, a green coloring matter, lignin and salts of potassa, lime, magnesia and iron. From a remedy so constituted, what should we justly expect but great activity and extended influence? Wylliesburg, Charlotte, March 1S51. Metastasis of Mumps to the Brain and Uterus. SUCCESSFULLY TREATED BY A. SNEAD, M. D., RICHMOND. [Read before the Medical Society of Virginia, April 1851.] Believing that the following case may, in some of its features, inte- rest the society as it has my own mind, I hope to be excused for de- taining it, by reading a short account of the case : On Monday, 31st March, being on a visit to Mrs. T., I was re- quested to see her servant Mary Ann. I found her to be a remark- ably tall, athletic woman, aged twenty-six years. On enquiry I re- ceived the following statement : On the Monday preceding she had been attacked with mumps in the right parotid. She had not however been so much indisposed thereby as to prevent her from attending to her duties, that of nurse to Mrs. T.'s child. On Friday night, last she experienced the first indications of the disease making its appear- ance in the left parotid. On Saturday and Sunday she felt more in- disposed, and on Sunday evening her head commenced to pain her, and had been so distressing as to prevent her from sleeping the greater part of the night. She had taken last night some aperient pills, by which her bowels had been three times moved, but without affording snead's case of mumps. 323 her any relief. She had vomited several times during the night and this morning ; had taken but little food on yesterday. At this time headach is distressing, and there is much intolerance of light ; head hot and temporal arteries throbbing ; pulse increased in frequency and force ; extremities cool but not cold. Her bowels having been freely moved, I ordered a hot mustard bath for her feet and legs, hoping by this means to relieve her of her sufferings ; but if not relieved, and es- pecially if she should grow worse, I directed I should be immediately informed of it. At 2 o'clock, P. M., I received an urgent message to visit her, and on arriving I found her verging on delirium. Her head was intensely hot and temporal arteries beating violently ; the extremities had warmed up, and pulse at rest, fuller and stronger. Head aching vio- lently, and great intolerance of light — had vomited. I observed in a vessel a small quantity of blood, and enquired of her if her nose had been bleeding — she replied in the negative. I then on enquiry ascer- tained she was menstruating, and learned it had set in on the previous evening. I asked if it was her regular time — she said no — but that it was at least ten days too soon. She stated that heretofore she had always been very regular, and that at such times she has suffered no pain, but that now there was very smart pain in the region of the womb, and that the discharge was greater than it was accustomed to be. On pressure being made on the hypogastrium she manifested considerable tenderness. I ordered her to be cupped without delay, and that 20 1 of blood should be taken from behind the ears. 5 P. M. The cups had been promptly applied, and at least 20 1 of blood had been taken. She had been greatly relieved by the loss of blood. Heat of head and surface lessened, and headach greatly mitigated. There has been no vomiting since she was cupped. On moving the head it becomes very painful — intolerance of light lessened. I prescribed calomel, 12 grains to be given at once, and after three hours to be purged off by salts and senna tea ; this to be repeated until the bowels had been actively moved. Sinapisms to be applied to the parotids. April 1st, 9 A. M. Took calomel and senna tea as directed. The bowels have been three time actively moved. She rested better last night, having enjoyed some refreshing sleep — expresses herself as being much more comfortable. She says her head is easy if kept quiet, but pains if it is moved — intolerance of light much diminished — pulse 80 and rather tense. Surface pleasant — very little heat of head — intolerance of light diminished — tenderness of hypogastrium less — catamenia continues. Directed a small blister to be raised over each parotid, and a draught of salts and senna tea to be taken at noon. 6 P. M. The surface over each parotid is well vesicated. Head entirely relieved — no pain on motion, neither does there remain any intolerance of light. She thinks the blistering has done much good. Pulse soft and less feverish than in the morning ; has had two alvine evacuations. Blisters to be kept dressed with poultices. No medi- cine. 324 manson's case. 2nd, 10 A. M. The patient has passed a comfortable night ; slept well ; has neither headach nor pain on motion, and there remains no intolerance of light. No fever — bowels have been twice moved. She expresses herself as being very much better. 4th. Since the 2d the case has continued to progress favorably, and visits were discontinued. I, however, incidentally saw her on the 6th, in her mistress's room, and on enquiring how she was, she said, " Well, except the numbness down her right arm and leg." Of this she had never before complained to me, but said she had felt it all the time I had been attending her. She left for the country the next day, so I do not know how long the numbness continued. The chief points of interest in this case are the state of the head and uterus. Was this a case of metastasis or mumps to the brain ? and was the condition of the womb a mere coincidence, or was there a connection between its state and the diseased parotids ? I conclude it was metastasis of mumps to the brain, from the fact that there appeared no other exciting cause for so violent a set of ce- rebral symptoms ; and the train of symptoms were such as I should expect to meet with in cases of metastasis. I further conclude so from the fact that the disease yielded to a course of treatment appro- priate to such a state of things. The blistering of the parotids ap- peared to produce a good and permanent effect, as after it had been done, there remained neither uncomfortableness of head nor intoler- ance of light. In answer to the second enqui^, I conclude that there is no reason why the genitals of the female may not become involved in this dis- ease as well as those of the male. In the two cases reported by Dr. Lindsly, in the Stethoscope, priapism was present in both, and in the latter case it was the first symptom that excited alarm for his patient. It is true that, ordinarily, the testes in the male and the mammae in the female are the organs to which translations take place in mumps. But why is this so? Can any one explain it? In this case let it be remembered, that the period for the catamenial flow had not arrived by at least ten days. Why should it now set in, accompanied by much pain in the uterus and very marked tenderness on pressure be- ing made on the hypogastrium, and this, too, in one in whom its flow had always been unattended by pain, and recurring only at the regu- lar times ? The mammas were not at all affected. How shall we ac- count for the benumbed feeling of the right side ? Was it that the left side of the brain had suffered during the attack a greater amount of injury than the right? The left parotid was the last attacked. A Case of Retention of Urine from Paralysis — Puncture of the Bladder above the Pubes — Recovery. BY OTIS F. MANSON, M. D., OF GRANVILLE COUNTY, N. C Although we readily concur with Mr. Liston, when he exclaims in characteristic language, that " there is no disease in which the patient is more liable to be bungled out of his life than in retention of urine," and that the instances are rare in which puncture of the bladder is manson's case of puncture of the bladder. 325 demanded, yet cases must present themselves to the most skilful, in which the bladder cannot be reached by its natural outlet, and in which paracentesis is the only alternative. Perfectly satisfied I am, from the convictions of my own mind, and from the concurrence of high surgical authority to whom the case has been minutely and accurately reported, that the operation in the instance I am about to relate was the only practicable means, under the circumstances, to rescue the patient from death. Alexander, a mulatto, aged 30, belonging to Major W. M. Sneed of this county, was injured by the falling of a heavy piece of timber upon him, which threw him prostrate on the ground, its whole weight resting for some moments upon the lateral regions of the abdomen. The accident occurring on the 25th of February last, paralysis of the inferior extremities of the bladder, and consequent re- tention of urine immediately ensued. On the evening of the 26th, Dr. William F. Henderson was called to see him. He found him suffering from great distension of the blad- der; no urine having passed since the reception of the injur}r. Pro- longed and persevering efforts were made by the doctor to introduce the catheter, but without success. On the morning of Thursday, the 27th, 1 was called in consultation, and found the patient in great agony from the distension ; the bladder was enormously enlarged, pro- jecting prominently over the pubes, its superior fundus extending above the umbilicus. Called in at this late moment, it is needless to enume- rate the difficulties I experienced in reaching the bladder : they will present themselves at once to the surgeon. It is only necessary to state that no means were left untried, no efforts spared to relieve the threatened organ, but without success. The patient's condition at this time was truly alarming; the distension, already beyond the bounds I had ever conceived the bladder capable of attaining, seemed rapidly increasing; violent paroxysms of rending pain, attended with a " sense of bursting," as the patient expressed himself, warned us that unless soon relieved, the case would be beyond the reach of art. The abdomen, seemingly stretched to the utmost by the turgid organ beneath, was hot and tender on pressure, to which being added the helpless condition of the patient from paraplegia, rendered his situa- tion distressing in the extreme. Puncture of the bladder being the only resort left to us, the patient was made aware of his imminent danger, and informed that the ope- ration presented the only mode of escape from death ; to the perform- ance of which he immediately consented. Operation. — The patient being placed on his back with his thighs semi-flexed, an incision was commenced with a scalpel about an inch above the pubes, and brought down to the symphisis, exposing the linea alba. The incision was continued by several sweeps of the knife, but diminished in length as I advanced, until the bladder was reached. The wound, therefore, presented a conical opening ; the small, exposed point of the bladder forming its apex ; the bladder was now touched with the point of a lancet, and a female catheter introduced with slight force and gentle rotary motion into the opening. An enormous quan- tity of foetid, bloody urine was discharged, followed by the most de- 36 326 manson's case of puncture of the bladder. lightful relief to the patient. The catheter was secured by two soft cords passing under the thighs, attached behind to a waistband, and another passing upwards fastened to it before, to the extremity of the catheter a gum elastic tube was attached, leading to a cup by which the patient was kept entirely dry, the tube being left constantly open. The alimentary canal having been fully evacuated previous to the operation, the patient was placed on his right side with the abdomen inclined downwards, and perfect rest enjoined in that position, the pa- tient soon fell asleep for the first time since the reception of the injury, and awoke comparatively comfortable. February 28. Condition improved ; has slept well ; pulse 90 ; very slight heat of skin ; some appetite ; feels no pain, no abdominal ten- derness or tension ; urine passes freely and copiously through the tube ; can move his legs slightly. Ordered ol. ricini ; rigid diet ; mu- cilaginous drinks. March 3. Still improving ; complete apyrexia ; pulse 60 ; wound healed closely around the tube ; paraplegia almost entirely relieved. Attempted to pass the catheter per urethram, but considerable urethri- tis still existing, desisted after very slight efforts. March 5. Some slight tenderness about the pubic region, and a con- siderable quantity of viscid, tenacious mucous, tinged with blood, occa- sionally blocking up the tube ; these symptoms of cystitis completely disappeared under the use of bals. copaiba. The catheter was withdrawn from the wound and a cork fitted around its middle to prevent its passing too deeply, as it constantly had a tendency to do. March 14. Urine passes to-day per vias naturalcs for the first time since the accident, the stream small, twisted and forked. March 18. Urine passes freely per urethram, a cork introduced into the end of the catheter. March 22. Patient passes his urine altogether per urethram. March 29. Urine now discharged as freely and regularly as in health. Catheter withdrawn from the supra-pubic passage, which was touched to the depth of half an inch with a pencil of lunar caustic. March 30. Strange to relate, but fortunately, not a drop of urine has passed through the wound since the tube was withdrawn ; wound almost entirely closed ; retouched with nit. silver. April 1. Artificial passage entirely closed. Discharged. Remarks. — So far as I can learn this operation has been usually fol- lowed by fatal consequences. Success in this case is probably refer- able to the following circumstances : lstly. The greatly distended bladder in mounting high up in the abdomen, carried the reflection of the peritonaeum upward before it, which only invests the superior and posterior surfaces of the organ, in consequence of which displacement, that important membrane was not wounded in making the supra-pubic opening. 2dly. The form of the wound was highly favorable to the exit of any urine which might pass outside of the tube, and thereby prevented infiltration. There was still less danger of wounding the peritonaeum, owing to the slight extent of the incision as the bladder was approached. palmore's obstetric case. 327 3dly. The mode of opening the bladder, by making a small clean incision, instead of the ragged, bruised wound inflicted by a trocar, which is generally used. 4lhly. The admirable conduct of the patient, who bore his suffer- ings with great fortitude, and conformed in every respect to advice, &c, particularly as regards rest, position and diet. I beg leave, in conclusion, to offer my thanks to Prof. Chs. Bell Gib- son for his kindness in having had made for me, under his immediate su pervision, the Prostate Catheter of Mr. Liston, for the case, and for his kind and judicious advice in relation to the after-treatment. Report of an Obstetrical Case. BY C. R. PALMORE, M. D. Mr. Editor — Supposing the recital of the following case, which occurred in my practice whilst connected with the " Obstetric Insti- tute" in Philadelphia, will be acceptable to you, and interesting if not instructive to the readers of your valuable magazine, I have taken the liberty to transmit a condensed report of it from my case-book for publication. It involves a question in obstetricy, which has always puzzled the young physician not a little, and which I hope this case will at least serve to direct the attention of practical physicians to the elucidation of the mystery with which teachers and books have surrounded it. Case. — April 10, 1850. Mrs. M. G. was seized with labor pains this morning. The labor proceeded very well, (the vertex presenting in the first position,) till the head emerged from the vulva. At this time the child took several deep inspirations and cried lustily. I immediately perceived, however, the umbilical cord around its neck, and on more minute observation discovered it drawn thrice very closely. The pains were now very severe, of the expulsive kind, which caused the funis to become tighter at every effort. I endeavored to pull the cord down and pass it over the head, but soon found the attempt useless from its extreme tenseness. I next attempted to dis- engage and suffer it to pass over the shoulders as they descended. This was also of no avail ; for I could scarcely insert one ringer be- tween the cord and neck, so closely was it fastened. My next duty I conceived was to suffer it to remain, or in other words trust to the vis medicatrix natures,. This negative plan was as nugatory as the others had been unfortunate. The child, which before had cried, now ceased. Its face became first dusky, then black, exhibiting plainly the compression of the jugular veins and the consequent stagnation of blood in the brain. Here then was no time to be lost. The only alternative at my command was to sever the funis. But here, (I should not call it a demon,) authority arose before me. Dewees, Ramsbotham, Meigs, Hodge, whose opinions we all recognize, passed in rapid review. I remembered only one similar case, that mentioned in Dr. Meig's Treatise on Obstetrics, page 295. That this was a similar case, I had no doubt. I resolved therefore to cut the cord, which having been done, the child, released from its halter, soon re- 328 palmore's obstetric case. vived ; its face gradually assumed its natural hue ; its breathing again commenced, and the mother's heart was illumed afresh by its re- awakened cry. A few bearing down pains soon sufficed to drive the child from the vulva. I now tied the cord. Nothing unusual occurred in the after treatment. Remarks. — It will be noticed that I pursued the usual course of treatment laid down in the books, and found this routine practice to- tally unavailing. Since the occurrence of the above case, I have ex- amined the subject pretty closely : have maturely considered the sa- lient points of the practice, and have come to the conclusion, that the treatment usually recommended is at least irrational, if not radically defective, and that it will not answer in practice. Upon a superficial examination, I know some may say that the suc- cess of the above case was post hoc, and not propter hoc. But if such persons would examine attentively the details given, they could not, in my opinion, refrain from being convinced that it was propter hoc. What are the dangers that are so particularly inculcated by teach- ers? There is only one, and to my mind this scarcely deserves the name of danger. I refer to the supposed probability of the child's dying from loss of blood. I say supposed, because I cannot conceive why this can take place, as the child's body presses the cord against the vulva, effectually serving the purpose of a ligature. And this ac- tually occurred in the case I have just narrated. The loss of blood was scarcely appreciable. This is the most prominent, if not the only objection, that can be urged against the treatment. The advantages are numerous, and, in my opinion, insuperable. It saves the child from impending death, and it empties the placenta of its retained blood ; thus allowing it to be more easily detached by the efforts of the uterus, or, if necessary, by the hand. Moreover, if the cord were suffered to remain around the neck, and the child to de- scend, the cord might be torn from the placenta, by the roots, or else it might draw the fundus of the uterus after it, and thus cause inversio Uteri. Those who have had this latter affection to deal with, will easily appreciate any plan recommended for its partial prevention. Stony Point Mills, Cumberland county, Va., April 23, 1851. Powers' and Weightman's Chloroform. Having failed in my efforts to test the purity of the chloroform pre- pared by Messrs. Powers and Weightman in time for the report of the committee on anaesthesia, I have since ascertained its specific gravity to be 1.47777 instead of 1.48, the chemical standard. Owing to the high temperature of the room where the scales were kept, I am sure this is rather under than over the true sp. gr. This extremely slight difference, if any, is altogether inappreciable in practice. It is highly commendable to the honor and skill of the manufacturers that they prepare the article for commercial purposes of such very great pu- rity. Does not this account for the fact that no injurious consequences have been observed in Richmond in about 1400 cases? J. BOLTON. AMERICAN MEDICAL ASSOCIATION. 329 The American Medical Association. The meeting of this body took place on Tuesday, May 6th, in St. Andrew's hall, at Charleston, S. C. The president, Dr. Mussey, of Ohio, took the chair at 11 o'clock, and called the association to order. Dr. Frost, on behalf of the committee of arrangements, read the list of delegates who had reported themselves ; (this list is too long to be published here — there were some two hundred in attendance, and they represented twenty-five states. The following gentlemen com- posed the delegation from Virginia: Drs. B. R. Wellford, P. C. Gooch, M. P. Scott, J. P. Tabb, H. C. Worsham, W. W. Par- ker, Medical Society of Virginia; C. P. Johnson and D. H. Tuck- er, Medical Department of Hampden Sydney College ; J. W. Walke and J. G. Lumpkin, Soc. Alumni of ditto, Hugh McGuire, Winches- ter Medical College, and F. W. Powell, Middleburg.) The association having been organized, Dr. Thos. Y. Simons, the chairman of the committee of the South Carolina Medical association, in a warm and hearty address, welcomed the delegates present from the other states to the city and state, on behalf of his associates, which was responded to in a becoming manner by the president. The president of the association read a letter from Dr. Stille, re- signing his office, in consequence of the impaired state of his health. On motion of Dr. Arnold, of Savannah, Ga., it was proposed that the letter of Dr. Stille be placed on record, in compliment to him, for the interest he has manifested in the association. Dr. Arnold offered the following resolution, which was adopted : Resolved, That a committee of one from each state represented in the association, to be chosen by their respective delegates, be ap- pointed to nominate suitable officers to be elected for the ensuing year. The association took a recess for ten minutes, to allow the delega- tions to elect their committeemen under the above resolution. On the re-assembling of the convention, the president reported the following gentlemen as having been selected as the nominating com- mittee : Drs. B. It. Wellford, of Virginia; Geo. Mendenhall, of Ohio ; Joseph Fithian, of New Jersey ; R. D. Arnold, of Georgia ; G. W. Miltenberger, of Maryland ; H. R. Frost, of South Caro- lina; N. G. Pittman, of North Carolina; W. H. Anderson, of Ala- bama ; A. H. Stephens, of New York ; Usher Parsons, of Rhode Island; Jos. Carson, of Pennsylvania; H. Adams, of Massachusetts ; Thos. Reyburn, of Missouri; Jas. Jones, of Louisiana; J. B. Flint, of Kentucky; John Sloan, of Indiana; C. Boyle, of the District of Columbia, and J. B. Lindsey, of Tennessee. The committee having retired, the president delivered an address of some length on matters connected with the association, and the advancement of medical science. It was received with marked at- tention and applause. 330 AMERICAN MEDICAL ASSOCIATION. The nominating committee, through their chairman, then read the subjoined names as suitable candidates for officers of the association for the ensuing year, viz : Dr. James Moultrie, of S. C, President. Dr. Geo. Heyward, of Mass.,") Dr. R. D. Arnold, of Geo., I TT. „ ••. Dx> r> \xr c \r r rice- Presidents. r. 13. R. Wellford, of Va., f Dr. J. B. Flint, of Kentucky, J Dr. H. W. Desaussure, of S. C, > 0 Dr. P. C. Gooch, of Va., \ Secretaries. Dr. Isaac Hays, of Pa., Treasurer. On motion of Dr. La Roche, of Pennsylvania, the report was ac- cepted, and the gentlemen thus nominated were elected the officers of the association for the ensuing year, and they were invited to take their seats on the platform. The president elect then took the chair, and in a few appropriate remarks, returned his thanks for the honor thus conferred on him by the association. The secretary read a report transmitted to him from the committee on unfinished business, appointed at the session of 1S50, which, On motion of Mr. Arnold, was accepted and laid on the table. On motion of Dr. Gaillard, of South Carolina, the following re- solution offered by Dr. Drake, of Cincinnati, at the session of 1S50, be taken up for consideration: Resolved, That the second section of the regulations of the associa- tion be so amended as to require that candidates for membership by invitation, be nominated in writing by five members ; that when elected they shall enjoy all the rights of delegates, and that all per- manent members shall be entitled to vote. After some discussion, on motion of Dr. A. H. Stevens, of New York, the resolution was referred to a committee, consisting of Drs. Drake, of Ohio, Wood, of Penn., and Wellford, of Virginia. Dr. Stevens, of New York, offered the following resolution, which was discussed by Drs. Storer, of Mass., and Moore, of Georgia, and finally rejected: Resolved, That a committee be appointed to report to the associa- tion the business before it, and to offer such suggestions as they may deem advisable for the due discharge of the same. On motion, the association adjourned to meet on Wednesday morn- ing at 10 o'clock. Second Day. The president called the association to order at 10 o'clock, and the minutes of the preceding meeting were read and confirmed. Dr. Wood asked and obtained leave to read the following report, on amending the constitution, signed by himself and Dr. B. R. Well- ford : The committee to whom was referred the proposition of Dr. Drake, for an alteration of the rules in relation to the admission and rights of members, have the honor to report as follows : AMERICAN MEDICAL ASSOCIATION. 331 There are two distinct branches of the proposition ; the first of which relates to the invitation of medical men not delegates to parti- cipate in the proceedings of the association ; the second has in view the extension of the right of voting to permanent members. The committee agree in the general purport of the first part of the proposition. As it now stands, the rule admits of a too easy admis- sion to the privileges of members, and it is susceptible of great abuse. It might happen, in a place where the number of physicians was very considerable, that sufficient might be introduced to control the deci- sions of the delegates. To guard against such a result, the committee recommend, that, in addition to the provision that none should be in- vited by the association unless upon a previous written proposal by five delegates, the existing rule should be so altered as not to confer upon the invited members the privilege of voting. In relation to the second part of the proposition, that, namely, which gives the privilege of voting to permanent members, the committee do not consider its adoption advisable, on the following grounds : This association is essentially a representative body. Its opinions are sup- posed to be those of the societies or associations by which the dele- gates are appointed, and go forth to the world with the authority in some degree of the medical profession generally. Now, if permanent members were permitted to vote, they would express their own indi- vidual opinions and support their own individual preferences; both of which might be in direct opposition to those of the delegates, and not fairly representative of general medical sentiment. It is easy to conceive that combinations among permanent members might be formed, more powerful than the properly delegated body, which might thus be overruled in its decisions. The opinions or wishes of a com- paratively few individuals might thus go forth to the world as those of the profession at large, and private purposes might be answered at the expense of the general good. This would defeat the main ob- jects of the association, and prevent it from continuing what it may now be considered to be, the exponent of enlightened medical senti- ment in this country. The committee, therefore, recommend that the question on Dr. Drake's proposition be taken separately upon its two branches; that the first be adopted with a modification, withholding the right of voting from invited members ; and that the second, which confers this right upon permanent members, be not adopted. GEO. B. WOOD, B. R. WELLFORD. Charleston, (S. C.,) May 7, 1851. Dr. Drake then read the subjoined minority report: The undersigned, a minority of the committee to whom was re- ferred the resolution for amending the second section of the constitu- tion, begs leave to report, that in his opinion it is expedient, and will be found promotive of the great objects for which the association was formed, that " members by invitation" should not be admitted, except under a written nomination by five members ; that when thus chosen, 332 AMERICAN MEDICAL ASSOCIATION. they should enjoy all the rights and privileges of delegates, including permanent membership ; and that all permanent members should be entitled to vote. With these views the undersigned respectfully sub- mits a revision of the resolution into the following : Resolved, That members by invitation shall be nominated in writing, by five members, which nomination shall be made a matter of record ; that when elected they shall enjoy the rights and privileges of dele- gates, and remain as permanent members of the association. Resolved, That all permanent members shall have the right of voting. Respectfully submitted. DAN. DRAKE. Dr. I. Hays moved to take up the majority report, which motion was carried. Dr. Arnold spoke against the article of the constitution authorizing invited members to vote. Dr. Wood explained his report, and urged its adoption. Dr. Davis, of Chicago, said that there was much misunderstanding in regard to the intention of the constitution in respect to the mem- bers by invitation. He hoped that the constitution would be strictly acted up to, and that members should be invited only " from sections not otherwise represented." Dr. Wood said his was an amendment, and not a repeal of the old provision. Dr. Drake responded — he had waited for arguments against his resolution, but had heard none. He then entered into a long argu- ment in favor of popularizing the association with the profession in the United States, and took ground in favor of a permanent place of meet- ing at Washington City. Dr. W. Atlee, of Pennsylvania, said he could see no harm in giving the privilege of voting to invited members who came from unrepre- sented localities, but was opposed to the right of voting proposed to be given to permanent members. Dr. Meigs, of Philadelphia, asked whether a gentleman would be invited to attend without any privileges, and went on to say that he hoped the association would have five, ten or even twenty thousand members at some future period. Dr. Hooker, of Connecticut, begged to be allowed to offer the fol- lowing resolution, the resolution of Dr. Drake, having been laid on the table for the present : Resolved, That no member be permitted to speak longer than ten minutes at any one time in any one debate. Dr. Philips, of New York, offered to amend the resolution by in- serting "15," which motion was lost. The resolution as offered by Dr. Hooker, was then adopted. Dr. Hays moved to lay the subject on the table, and added that by a constitutional provision it was required to lay over one year. The motion was seconded by Dr. Tucker, of Virginia. Dr. Dickson, of South Carolina, asked if the motion swept off the whole resolution, and was answered affirmatively by Dr. Hays. AMERICAN MEDICAL ASSOCIATION. 333 Dr. said if the matter was postponed now they would not be out of difficulty, because all that is necessary to defeat it next year would be to move to amend it, and it would have to lay over a year again, &c. The matter was finally laid on the table. Dr. Wood, of Pennsylvania, called up the second part, or that por- tion giving to permanent members the right to vote. The majority of the committee accepted the substitute of the mi- nority, which was read as follows, viz : Resolved, That all permanent members shall have the right of voting. Dr. Dickson urged the adoption of the above resolution. Dr. Hays, of Philadelphia, remarked that the constitution had not been studied by the gentleman who had urged the adoption of the re- solution, and spoke in opposition to the measure. Dr. Thompson, of Delaware, supported Dr. Hays, and hoped that the whole matter would be laid over for a year. Dr. Dickson observed that he had been accused of ignorance of the constitution. He hoped to have these gentlemen always here to in- struct him. Dr. Bond, of Maryland, took part in the discussion. Dr. Adams, of Massachusetts, remarked that they ought to strike out the words "permanent delegates" from the constitution, and was proceeding with his remarks, when the gentleman was called to order. The question was here taken on the adoption of the resolution, which was lost by a large majority. Dr. I. Hays, the treasurer of the association, then read the report of the committee of publication and also the report of the treasurer. The subjoined resolutions, appended, were read and adopted : 1. Uesolved, That the assessment for the present year shall be $3. 2. Resolved, That those delegates who pay the assessments shall be entitled to one copy of the transactions for the present year, and that the payment of two dollars, in addition, shall entitle them to two additional copies. 3. Resolved, That permanent members shall be entitled to one copy of the transactions for the present year on the payment of two dollars, and three copies on the payment of five dollars. 4. Resolved, That societies which have been represented in the association shall be entitled to copies for their members on the same terms that copies are furnished to permanent members. 5. Resolved, That permanent members, unless present at the meet- ing as delegates, shall not be subject to any assessment. 6. Resolved, That any delegate who is in arrears for his annual assessment shall not be considered as a permanent member. 7. Resolved, That the several committees be requested to bring to the meeting of the association their reports, correctly and legibly transcribed, and that they be required to hand them to the secretaries as soon as they have been read. All which is respectfully submitted. ISAAC HAYS, Philadelphia, April 20, 1851. D. FRANCIS CONDIE. 37 334 AMERICAN MEDICAL ASSOCIATION. Dr. Drake, of Ohio, moved that the report on surgery be read first. Adopted. Professor Eve, chairman of the committee on surgery, then pro- ceeded to read his report. A motion was made by Dr. Davis to commit the same to the com- mittee on publication ; which was adopted. Dr. Hays moved to read Dr. Flint's report by its title — Practical Medicine — and refer the same to the committee on publication, which motion was adopted, and the several hundred copies printed and fur- nished by the author were directed to be distributed among the dele- gates present. A motion was then made to adjourn till 5 o'clock, P. M., which was adopted. Afternoon Session. The president having called the meeting to order, Dr. Boyle, of Washington, offered a resolution that the association in future meet in Washington city. Dr. Gooch extended an invitation from the Medical Society of Virginia to hold the next meeting in Richmond city, which he said was in accordance with the instructions of the delegation, and Dr. Carter P. Johnson, from the medical faculty of Hampden Sidney college, presented an invitation to the same effect. Invitations were also presented by Dr. Jones, of the University of Louisiana, to meet at New Orleans, and Dr. J. P. Johnston, of Missouri, to meet at St. Louis. The resolution and invitations were referred to the committee on nominations. The president suggested the propriety of appointing the standing committees at an early day. Dr. Wood remarked that there was a proposition to abolish stand- ing committees. Dr. Hays said he was opposed to these committees, but would not press an alteration. Dr. Tucker moved that the appointment of the standing commit- tees be referred to the committee on nominations, which motion was adopted. Dr. Jones, of Louisiana, resigned as a member of the committee of nominations, and Dr. Fenner, of New Orleans, was appointed in his place. Dr. Parsons then moved that the committee of nominations be re- quested to resume its labors, which was adopted. Dr. Wragg, of Charleston, moved that the report of the committee on prize essays be read, and then that the obstetric report be brought up. Carried. The report on prize essays was then read, and the resolutions ap- pended thereto were adopted. When, on motion of Dr. Ready, of South Carolina, the whole mat- ter was referred to the committee of publication. Dr. Storer, of Boston, chairman of the committee on obstetrics, read the report on that subject. He stated that he had received a AMERICAN MEDICAL ASSOCIATION. 335 letter from Dr. Thompson, of Illinois — that he was the only member of the committee who had aided him in any degree. He mentioned this fact, because he had to hold himself entirely responsible for all the inaccuracies, &c. Dr. Phelps, of New York, moved that the report be referred to the committee of publication. Dr. Robertson, of South Carolina, moved that the statistics al- luded to in the report be stricken out, as they had been taken from a source not very reliable. Dr. Storer seconded the motion. Dr. Bond moved to postpone the report until morning, which was seconded by Dr. Gilman. A short debate here ensued ; when it was finally agreed to re-com- mit said portion of the report, to be corrected and laid before the as- sociation in the morning. On motion, the association adjourned to meet on Thursday morn- ing at 10 o'clock. Third Day. The president, Dr. James Moultrie, took the chair at 10 o'clock. The minutes of the previous meeting were read, and after some slight amendments, were confirmed. Dr. J. M. Smith, of Massachusetts, moved that the report of the committee on medical education be made the special order, after the disposal of the report on the committee of obstetrics. Dr. Gaillard, on behalf of the committee of arrangements, read a list of delegates reported and registered since the last report. Dr. Campbell, of Georgia, presented a model of a malformation of the knee joint, the patella being absent. Dr. Wood, of Pennsylvania, offered the following resolution : Resolved, That colleges, exclusively of dentistry and pharmacy, are not recognized by the association as among the bodies authorized to send delegates to its meetings. Dr. Wood, of New York, moved to amend, by dividing the resolu- tion, so as to make the question, first, on the reception of delegates from colleges of dentistry ; secondly, on the reception of delegates from colleges of pharmacy. The amendment having been accepted, the question of the recep- tion of delegates from colleges of dentistry was debated. Dr. Lamb moved an indefinite postponement of the resolution, which was lost. Dr. Yard ley, of Pennsylvania, asked and obtained leave to read a resolution from the Philadelphia county medical society. The discussion of the original question was then resumed. A motion was finally marie by Dr. Hays, of Pennsylvania, that the whole resolution of Dr. Wood, including colleges of dentistry and pharmacy, be referred to a special committee of five members, which resolution was adopted. On motion of Dr. Yardley, of Pennsylvania, the resolution pre- 336 AMERICAN MEDICAL ASSOCIATION. sented by the Philadelphia county medical society was also sent to the same committee. Dr. Jones, of North Carolina, offered the following resolution : Resolved, That all the medical colleges in the United States are hereby earnestly and respectfully requested to hold a convention, through delegates respectively chosen by them, at least once in every six years, to take into consideration the proper method of harmoniously elevating the standing of medical education in the said colleges. The order of the day was then called up, when Dr. Storer re- ported that he had erased the statistics referred to yesterday, and that he placed the report in the hands of the association. Dr. S. said that there was objection to the remarks on the subject of Dr. Gil- man's paper on the speculum relm. He asked that he be permitted to remove the unnecessary expression of opinion in regard to that sub- ject. He further added, that he had taken from the journals these facts, and was not therefore responsible for the correctness of the pa- pers, &c. Dr. Bond, of Maryland, remarked that there were charges in these reports which he did not individually endorse, but which go out in a book under the sanction of the association. On motion of Dr. Davis, the report was referred to the committee of publication. At this stage of the proceedings, Professor S. S. Holdeman, of Lan- caster county, Pennsylvania, through Dr. John L. Atlee, presented to the association an essay on Latin pronunciation, of which he is the author ; and which, on motion of Dr. Atlee, was referred to the com- mittee on medical literature. On motion, the regular order was suspended for the reception of the report of the committee of nominations, which was read and laid on the table. Dr. Hays then called up the resolution on page 43, vol. 2 of the Transactions of the Association, and moved to strike out " all that re- lates to committees," &c. The motion was seconded by Dr. Stevens, and urged by Dr. Drake, who announced some ten or twelve special points, which he said ought to occupy the association, instead of being occupied with epitomes of Rankin & Braithwaite. Dr. Hooker, of Conn., spoke of the looseness of committees and editors of journals. Dr. Davis thought that they could decide on the matter at once. Dr. Hays proposed to dispense with the standing committees. The question was then taken on the resolution, which was adopted. Dr. Wood, of Penn., offered the following resolution, which was adopted : Resolved, That a committee be appointed to take into consideration the arrangement of a committee for future action, to report as speedily as possible. The chairman of the committee on medical education was about to read the regular report on that subject, when Dr. Drake moved the suspension of the reading till after the recess, as it was a very long report. AMERICAN MEDICAL ASSOCIATION. 337 On motion of Dr. Johnston, of Missouri, the report of the commit- tee on medical literature was then taken up. Dr. Desaussure announced that Dr. Davis would read a paper entitled " An experimental enquiry concerning some points connected with the process of assimilation and nutrition." Dr. Reyburn, of Missouri, presented and read the report of the committee on medical literature. In the course of his reading the re- port, he gave way to a motion to adjourn, which was carried. Afternoon Session. The president took the chair at half past 5 o'clock. The secretary announced the following gentlemen as having been appointed by the president, under a resolution of this morning, concern- ing a committee for the arrangement of business for the occupation of the association in future : Drs. G. Wood, of Pennsylvania, J. Hays, D. Drake, A. H. Stevens, W. Hooker, B. R. Wellford and S. H. Dickson. The following gentlemen were appointed a committee under a re- solution in regard to schools of pharmacy and dental surgery, viz : Drs. Hays, Stevens, Yardley, Storer and Jones. Dr. Dickson moved the following preamble and resolutions, which were seconded by Dr. Lebby, and unanimously adopted without de- bate : Whereas efforts are being made to repeal the law of 1847, which confers protective ranks on the members of the medical department of the army — Therefore, Resolved, That the American Medical Association views with re- gret the existence of hostility to the act of congress, approved Febru- ary 11, 1S47, which confers legal rights and equality with other staff departments on the medical officers of the army, and gives them a position to which the importance and character of the profession enti- tle them. Resolved, That copies of these resolutions, with the resolutions of the association passed at its last annual meeting on the same subject, be transmitted to the secretaries of war and of the navy, through the chiefs of the medical department of each service, and to the presiding officers of the senate and house of representatives of the United States. The reading of the report of the committee of medical literature was then concluded. On motion, the report was received and referred to the committee on publication. The report of the committee on medical education was then called for, and as the hour was late, the chairman read only so much of it as relates to demonstrative midwifery, which had by special resolution been referred to the committee. On motion, the report was accepted, and referred to the committee on publication. Dr. Dickson then offered the following resolution, which was adopted : 338 AMERICAN MEDICAL ASSOCIATION. Resolved, That this association unanimously approve of the opinions expressed in the report of the committee on medical education in re- spect to demonstrative midwifery. The association then adjourned to meet at 10 o'clock on Friday. Fourth Day. The president, Dr. James Moultrie, in the chair. The minutes of the last meeting were read and confirmed. The report of the committee on medical education being the special order, Dr. Stevens, of New York, asked and obtained leave to intro- duce the following resolutions : Resolved, That the members of this association cannot separate without expressing their grateful sense of the hospitalities and nume- rous delicate attentions received from their medical brethren of South Carolina and the citizens of Charleston. Resolved, That a committee be formed to procure a tablet, with a suitable inscription, commemorative of this meeting and the feeling it has elicited, to be placed at the disposal of the Medical Association of South Carolina. Inscription. — " This tablet is here placed by the American Medical Association, to commemorate their annual meeting in the city of Charleston in May 1851, and to signalize their gratitude for the extra- ordinary professional and social enjoyments that accompanied it." The resolutions having been seconded were adopted ; and Dr. Stevens further moved that Drs. Hayward, of Mass., F. A. Ramsey, of Tenn., and himself constitute the committee. Dr. Ramsey, of Tenn., asked and obtained leave to read a letter from Dr. E. D. Fenner, of Louisiana, and offered the following reso- lution on the subject, which was adopted : Resolved, That the efforts of Dr. Fenner to place on a firm and durable basis an annual publication, embracing medical reports from the whole Southern portion of the Union, merit the commendation of this association, and should receive solid support from American phy- sicians. Dr. Hays, of Pa., asked and obtained leave to call up for conside- ration so much of the report of the nominating committee as relates to the selection of the next place of meeting of the association, and the appointment of the committee of arrangements and the committee of publication, the other standing committees having been abolished. The report having been read, Dr. Drake, of Ohio, made an urgent appeal in favor of Washington city as the next place of meeting. The question being taken on the adoption of that part of the report of the committee, which proposed Richmond, (Va.,) it was adopted by a large majority. The question being taken on the confirmation of the committee of arrangements and publication, the nominations of the committee were confirmed. Richmond, Va., was selected as the nest place of meeting by the association, and the following gentlemen appointed a committee of arrangements, viz : Drs. R. W. Haxall, Chairman ; Carter P. Johnson, James Beale, Chas. B. Gibson, S. Maupin, R. D. Has- AMERICAN MEDICAL ASSOCIATION. 339 kins, C. S. Mills and M. P. Scott. Committee of Publication — Drs. Hays, of Pa., G. Emerson, of Pa., D. F. Condie, of Penn., H. W. Desaussure, of So. Ca., J. Parrish, of Penn., P. C. Gooch, of Va., and G. W. Norris, of Penn. Dr. Hooker, of Conn., chairman of the committee on medical edu- cation, completed the reading of the report on that subject, and of- fered the following resolutions : Resolved, That the abuses which exist in the modes of medical edu- cation pursued in this country demand the serious consideration of the profession. Resolved, That free discussion in relation to these causes is an im- portant means of effecting their removal. Resolved, That in the opinion of this association no effort to remove these abuses can succeed, that is not based upon a reform in the pub- lic sentiment, both of the profession and of the community. Resolved, That this reform, so far as the profession is concerned, is to be effected mainly through its organizations, and that it is therefore incumbent upon every physician to do all that he can to give them character and efficiency. Resolved, That this association has confidence in all proper efforts which have for their object a reform in the sentiments and practiceof the community in relation to medicine and the medical profession. Resolved, That the recommendations of this association at its former meetings in regard to education, both preliminary and medical, be re- affirmed, and that both the schools and private preceptors be still urged so to do their duty as to secure to the community a well-edu- cated profession. Resolved, That in the work of medical reform, while all precipitate movements should be avoided, we should aim at a steady advance, from year to year, till a thorough S37stem of education be established by the profession throughout our country. Dr. Wood, of Pennsylvania, asked leave to suspend the order usu- ally taken with reports. Permission being granted, he read the fol- lowing report, wThich was adopted : The committee to whom was referred the subject of arranging a plan of committees for future action, in place of the standing com- mittees abolished by the association, have the honor to report as fol- lows : It appears to them that the most feasible plan of accomplishing the objects of the association is to select certain subjects which may be considered as suitable for investigation, and to refer these subjects to special committees, to be appointed before the close of the present session, and to report to the next. Such a selection the committee have accordingly made, and will offer to the consideration of the as- sociation. As an additional means of securing valuable contributions, they propose, also, the appointment, of a committee, whose business it shall be, in the interval between this and the next session, to receive original volunteer papers, upon any subjects which their authors may choose, to decide upon the merits of these papers ; and to present to 340 AMERICAN MEDICAL ASSOCIATION. the association, at its next session, such of them as they may deem worthy of receiving this direction. With a view to increase competi- tion, they think it advisable that a prize of fifty dollars, or a gold me- dal of that value, be awarded to each of the five papers presented to the association, or any smaller number of them, which the committee may consider most meritorious and the association may resolve to publish. In reference to the resolution presented in the report of the stand- ing committee on medical literature, and referred to the present com- mittee, they have only to observe that, as its ends will probably be most effectively obtained by the adoption of the general plan which they have already brought before the notice of the association, they do not consider it expedient to make any further report. As to the appointment of the special committees referred to, your committee think that the most convenient plan will be to refer to a special committee the nomination of a chairman for each, who shall then select, at his convenience, two individuals to aid him, with the restriction only, that the persons so selected shall be members of the association. To the same nominating committee may be referred the appoint- ment of the general committee, whose business will be to receive and judge whatever papers they may receive. As this general committee must frequently compare opinions, it will be desirable that they should reside near each other, and it is accordingly proposed that they should be chosen from one neighborhood. If the plan be found to work well, this locality may be changed every year, so that each section of the Union may in its turn be charged with this duty. The committee would suggest that the general committee should be first chosen from members of the association, residing in Boston or its neighborhood, as the most Northern point. To embody these suggestions in due form, the committee offer the following resolutions : 1. Resolved, That committees of three be appointed to investigate and report severally on the following subjects : 1st. Causes of the tubercular diathesis. 2d. Blending and conversion of the types of fever. 3d. The mutual relations of yellow fever and bilious remittent fever. 4th. Epidemic erysipelas. 5th. Acute and chronic diseases of the uterus and its neck. 6th. Dengue. 7th. The milk sickness, so called. 8th. Endemic pi'evalence of tetanus. 9th. Diseases of parasitic origin. 10th. Physiological peculiarities and diseases of negroes. 11th. The action of water on lead pipes, and the diseases which proceed from it. 12th. The alkaloids which may be substituted for quinia. 13th. Permanent cure of reducible hernia. 14th. Results of surgical operations for the relief of malignant dis- eases. 15th. Statistics of operations for removal of stone in the bladder. AMERICAN MEDICAL ASSOCIATION. 341 16th. Cold water dressings. 17th. The sanitary principles applicable to the construction d£ dwellings. 18th. The toxicological and medicinal properties of our crypto- gamic plants. i 19th. Agency of the refrigeration produced through upward radia-r, tion of heat as an exciting cause of disease. 20th. Epidemic diseases of New England and New York. 21st. Epidemic diseases of Pennsylvania, New Jersey, Delaware and Maryland. 22d. Epidemic diseases of Virginia and North Carolina. 23d. Epidemic diseases of South Carolina, Georgia, Florida and Alabama. 24th. Epidemic diseases of Mississippi, Louisiana, Texas and Arr kansas. < 25th. Epidemic diseases of Tennessee and Kentucky. 26th. Epidemic diseases of Missouri, Illinois, Iowa and Wisconsin. 27th. Epidemic diseases of Indiana, Ohio and Michigan. II. Resolved, That a committee of nomination be appointed, whose duty it shall be to nominate the chairman for each of the above com- mittees. III. Resolved, That each of the chairmen thus nominated shall se- lect, at his earliest convenience, the members of the association to complete the committee. j IV. Resolved, That a committee of five members be appointed, to be called the committee for volunteer communications, whose duty it shall be, in the interval between the present and the next succeeding session, to receive papers upon any subject from any persons who may choose to send them, to decide upon the merits of these papers, and to select for presentation to the association, at its next session, such as they may deem worthy of being thus presented. V. Resolved, That the committee for volunteer communications shall have the power to form such regulations as to the mode in which the papers are to be presented, and as to the observing of secrecy or otherwise, as they may think proper. VI. Resolved, That the selection of the members of this committee be referred to the same nominating committee, whose duty it will be to appoint the chairman of the several special committees as above directed, with this restriction, that the individuals composing it shall reside in the same neighborhood. • VII. Resolved, That a prize of fifty dollars be awarded to each of the volunteer communications reported on favorably by the committee, and directed by the association to be published : Provided, That the number to which the prize is thus awarded do not exceed five ; and, provided, also, if the number approved and directed to be published exceed five, that in such case the prize be awarded to the five which the committee may determine to be most meritorious. All of which is respectfully submitted. GEO. B. WOOD, Chairman. ; Charleston, May 9th, 1851. 38 342 AMERICAN MEDICAL ASSOCIATION. Dr. Hays, of Pennsylvania, gave notice, that at the next meeting of the association he should offer an amendment to the constitution, line 4, so as to read " $10, instead of $ 3." Dr. Atlee, of Pennsylvania, remarked on the value of the report of the committee on medical education, and offered the following re- solution, which was adopted : Resolved, That it be recommended to the several state medical so- cieties throughout the Union, to procure are-publication of the report of the committee on medical education, for general distribution among the profession. Dr. Drake offered the following resolution : Resolved, That in the opinion of the association, the students of our schools should be required to matriculate within the first days af- ter the opening of the sessions, and continue their attendance to the end of the terms, taking with them evidence of the same, to be presented with tickets of the professors when they become candidates for de- grees. The resolution was adopted, and Dr. Gibson moved to defer the filling up of the blank. Some discussion arose on this point, when the resolution was left to read, " within the first days," &c. The report of the committee on medical science was then called up, when a letter was read from Dr. Dowler, chairman of said com- mittee, regretting his inability to be present, and the necessity of send- ing it. Dr. Fenner then read the outlines of the report, and asked per- mission to retain the same for revision, copying, &c, which was granted. Dr. Mauran offered the following resolution, which was adopted : Resolved, That the committee on publication be instructed to print conspicuously upon the title page of the forthcoming volume of the transactions, the following declaration, viz : " The American Medical Association, although formally accepting and publishing the reports of the various standing committees, holds itself wholly irresponsible for the opinions, theories or criticisms therein contained." Dr. Storer moved the following resolution, which was adopted : Resolved, That the hearty thanks of this association be presented to their late secretary, Alfred Stille, M. D., for his constant, un- wearied and invaluable services since its first organization. The secretary then read the report of the committee on " adulte- rated drugs." Dr. Gooch expressed his disapprobation of the report, on account of its meagreness, &c A motion was made to refer the same to the publication committee ; which was rejected. Dr. Gooch then moved to lay it on the table, which motion prevailed. Dr. Gaillard, of South Carolina, chairman of the committee on hy- giene, presented an outline of the report on that subject. Referred to the committee of publication, with authority to append thereto a pa- per now in preparation, on the mortuary statistics of certain cities. Dr. Drake, of Ohio, offered the following amendments to the con- stitution, which were read and ordered to lie over under the rule : AMERICAN MEDICAL ASSOCIATION. 343 " All members by invitation must be nominated in writing by five members of the association, whose names shall be recorded in the mi- nutes. When elected, they shall enjoy all the rights and privileges of delegates, and remain permanent members of the association. " All permanent members shall be entitled to vote, and when they attend a meeting of the association, their respective names shall be re- gistered, and each shall pay the sum required from a delegate." The secretary read a protest from the Iowa University, against the representation of Rush medical college in this association. Dr. Jervey moved to refer the protest to a special committee, to report at once. Dr. Wood moved to refer it to the committee on colleges of phar- macy and dentistry, which was carried, Dr. Jervey having withdrawn his motion. Dr. Wood read the following report of the committee of nomina- tions, which was adopted : The committee to whom was referred the nomination of the chair- men of the several special committees, to report at the next session, and also of the committee for volunteer communications, report that they have fulfilled the object of their appointment, and offer the fol- lowing list of chairmen to the committees first referred to, viz : 1st. Dr. D. F. Condie, Philadelphia, chairman to the committee on the causes of the tubercular diathesis. 2d. Dr. S. H. Dickson, of Charleston, S. C, on the blending and conversion of the types of fever. 3d. Dr. James Jones, of New Orleans, on the mutual relations of yellow and bilious remittent fever. 4th. Dr. John B. Johnston, of St. Louis, Mo., on epidemic ery- sipelas. 5th. Dr. Charles D. Meigs, of Philadelphia, acute and chronic dis- eases of the neck of the uterus. 6th. Dr. J. P. Jervey, of Charleston, S. C, on dengue. 7th. Dr. Daniel Drake, of Cincinnati, milk sickness — so called. 8th. Dr. Lopez, of Mobile, Ala., epidemic prevalence of tetanus. 9th. Dr. George B. Wood, of Philadelphia, on diseases of parasitic origin. 10th. Dr. R. D. Arnold, of Savannah, Geo., on the physiological peculiarities and diseases of negroes. 11th. Dr. Horatio Adams, of Waltham, Mass., on the action of wa- ter on lead pipes, and the diseases which proceed from it. 12th. Dr. Jos. Carson, Philadelphia, on the alkaloids which may be substituted lor quinia. 13th. Dr. Geo. Hayward, Boston, Mass., on the permanent cure of reducible hernia. 14. Dr. S. D. Gross, Louisville, Kentucky, on results of surgical operations for the relief of malignant diseases. 15. Dr. James R. Wood, New York, statistics of the operation for the removal of stone in the bladder. 16. Dr. Charles A. Pope, St. Louis, Missouri, water, its topical uses in surgery. 344 AMERICAN MEDICAL ASSOCIATION. ' 17. Dr. Alex. H. Stevens, New York, sanitary principles applica- ble to the construction of dwellings. ' 18. Dr. Porcher, Charleston, S. C, toxicological and medicinal pro- perties of our cryptogamic plants. v 19. Dr. G. Emerson, Philadelphia, agency of the refrigeration pro- duced through upward radiation of heat, as an exciting cause of disease. 20. Dr. Worthington Hooker, Connecticut, on the epidemics of New England and New York. 21. Dr. John L. Atlee, of Lancaster, Penn., on the epidemics of New Jersey, Pennsylvania, Delaware and Maryland. 22. Dr. Robert W. Haxall, Richmond, Va., on the epidemics of Virginia and North Carolina. ■ 23. Dr. Wm. M. Boiling, Montgomery, Ala., on the epidemics of South Carolina, Georgia, Florida and Alabama. 24. Dr. Ed. H. Barton, Louisiana, on the epidemics of Mississippi, Louisiana, Texas and Arkansas. 25. Dr. Sutton, Georgetown, Ky., on the epidemics of Tennessee and Kentucky. 26. Dr. Thomas Reyburn, Missouri, on the epidemics of Missouri, Illinois, Iowa and Wisconsin. 27. Dr. George Mendenhall, Ohio, on the epidemics of Ohio, Indi- ana and Michigan. The following gentlemen were appointed on the committee for vo- lunteer communications, viz : Drs. Geo. Hayward. J. B. J. Jackson, D. H. Slorer, and Jacob Bigelow of Boston, and Dr. Usher Parsons, Of Providence, R. I. Signed in behalf of the committee. GEO. B. WOOD, Chairman. Charleston, Friday, May 9th, 1851. The president read an invitation from the committee of reception to a steamboat excursion on the Cooper and Ashly rivers, on Saturday. Dr. M'Intyre, of New York, proposed that the code of ethics and constitution of the association be recommended to be published by the several state societies. Proposition adopted. • Dr. Grimshaw offered the following resolution, which was laid on the table : Resolved, That medical colleges, in publishing statements of the number of medical and surgical cases treated at their dispensaries, act contrary to the spirit of the code of ethics adopted by this body. Adjourned till 5 o'clock. Afternoon Session. > The association re-assembled at 5 o'clock, Dr. B. R. Wellford, of Virginia, vice-president in the chair. U The special order was called for, and Dr. Davis, of 111., read a pa- per on the influence of certain diet on the functions of respiration and calorification, &c. The president, Dr. James Moultrie, resumed the chair. -'. Dr. Hays moved to proceed with the consideration of unfinished business. MEDICAL SOCIETY OF VIRGINIA. 345 Dr. Grimshaw offered the subjoined resolution, which was adopted: Resolved, That the thanks of the association be returned to Dr. Da- vis for the paper just presented by him. Dr. F. A. Ramsey, of Tenn., called up, as unfinished business, the resolution offered yesterday by Dr. Jones, of Tenn., and not then acted upon, to which Dr. Grimshaw offered the following amend- ment : " And that the first convention be held before the first of May 1852." The question being taken on the resolution and the amend- ment, they were both negatived by a large majority. Dr. Phelps, of New York, offered the following resolutions, which were unanimously adopted : Resolved, That the warmest thanks of the association be tendered to the trustees of the St. Andrew's Society, for the gratuitous use of their very convenient and eligible hall ; and to all those other institu- tions and reading-rooms, which have been so freely thrown open for the inspection and use of the members. Resolved, That the committee of arrangements receive our most grateful acknowledgments for the very handsome, and indeed magnifi- cent manner in which they have provided for the entertainment and pleasure of the delegates from abroad, during their sojourn in the city of Charleston. Resolved, That not only the profession of medicine, but also private munificence, and the kind attentions of the citizens generally, have conspired in manifestations of that urbanity of manner, and that un- wearied and kind attention, which commands not only our profound admiration, but will be followed by the most pleasing recollections so long as life and thought shall endure. On motion of Dr. Stevens, the above resolutions, with those of- fered by him at the morning session, were ordered to be published in the city papers. Dr. Johnston, of St. Louis, moved to adjourn sine die, which was adopted. The vice-president in the chair, Dr. Wellford, of Virginia, then congratulated the association on the happy termination of its labors, and declared it adjourned, to meet again in Richmond, Va., on the first Tuesday in May next. The Medical Society of Virginia. The twenty-seventh annual meeting of the Medical Society of Vir- ginia was held at the hall of the Richmond Library Association, on Tuesday evening, May 20th, 1851 — Dr. Robert W. Haxall (Pre- sident) in the chair. The attendance of members was very large, though there were not as many from the counties as we had hoped to see. After reading the minutes of the preceding meeting, the President addressed the society as follows : Gentlemen, — Before entering on the duty before us of electing the offi- cers of this society, Jewish, with your permission, to say a word or two. It is known to most of you, if not to all, that I have expressed the 346 MEDICAL SOCIETY OF VIRGINIA. wish that some other member of our body might be called upon to preside over its deliberations for the coming year. Not only am I in- fluenced by a desire to see the principle of " rotation in office" esta- blished among us, but I am also swayed in some degree by a feeling which attaches to my own personal convenience. When I accepted the office which you did me the honor to confer upon me, I deter- mined most faithfully and conscientiously to perform its duties as far as I was able so to do. No considerations of social enjoyment have I ever permitted to come in conflict with these duties ; nay, I might go farther and say, that on more than one occasion my professional engagements have been made to yield to those obligations which de- manded my presence here. In thus expressing myself, you will not, I am sure, accuse me of any feeling akin to egotism, for I am as sensible as any of you can possi- bly be, that the interests of this society would have been subserved even in a far greater degree by the selection of some other individual. If I have been punctual in my attendance, and impartially rigid in the performance of my duty, it has arisen mainly from a sentiment which I have ever entertained, viz : that one should never accept an office unless he intended to bestow upon it his undivided attention. If I have succeeded in eliciting your good will, my highest ambition has been answered. Although, gentlemen, I have really not had it in my power to re- spond, as I wished to do, to a resolution unanimously adopted by the society some two months since, yet I cannot permit the occasion to pass away without congratulating you upon our present prosperous condition. Nine years ago, when this society was re-organized, a most praiseworthy spirit seemed, for a time at least, to infuse itself among us ; our meetings were well attended, papers were regularly read, and our discussions were conducted with considerable zeal — but it was only for a time. If since that period our progress has not con- stantly been onward — if some among us can remember a year or two of comparative lukewarmness, does not the flattering prospect before us amply repay the cares and toils through which we have passed ? It will not be indecorous in me to assert — for the position which I have held for the last year has prevented me from taking part in our debates — that in my opinion they are now conducted with an ability worthy of all commendation. The generous rivalry, not for master- ship merely, but for the elucidation of truth, which has so often dis- played itself in this hall, will never separate us in feeling, but will contribute rather to rivet still closer those kindly sentiments which now exist. Nor are we the sole beneficiaries of a purpose so laudable — so pro- ductive of good. Our example has become in some degree conta- gious, and the proof of the assertion is exhibited in the fact that within the last few months a very large accession to our numbers has taken place. If present and immediate benefit does not accrue to those who do not reside among us, from the discussions which take place here, they no doubt look with much interest to the reports which are sub- mitted to their inspection. In some measure it may be said that this MEDICAL SOCIETY OF VIRGINIA. 347 is due to non-resident members, as a partial remuneration for the en- couragement given in permitting us to record iheir names. I am sure I need not submit a single remark calculated to stimu- late the energies of our members. Endowed with as large a share of natural ability as usually falls to the lot of a like number of indivi- duals, there is no reason why we may not contribute our mite to the general fund of medical improvement ; and perhaps it may be some- what gratifying to know that more than one paper has emanated from this society which has been noticed in terms of marked commendation. Let us then, gentlemen, bring to our labors a zeal and an industry which shall know no other limit than the accomplishment of the ends we have in view. With no sinister purposes to subserve — no private piques to disturb the smooth current of our way, let us continue to encourage those fraternal feelings which now so happily abound. And if it be that no brilliant discovery shall hand down the name of any to an admiring posterity, the consciousness that we have faithfully acquitted ourselves of the obligations which rest upon us will serve to brighten the memory of the past, when the decrepitude of years shall have unfitted us for the active pursuits of life. The treasurer's report was then presented and read, and his books laid before the society. On motion, a committee of three was ap- pointed to examine and audit his accounts. The report exhibits a surplus in the hands of the treasurer over and above all liabilities. In the absence of the librarian no report was made as to the condi- tion of the library. We are sorry to see no steps taken to build up a scientific library commensurate with the dignity and importance of the society. We hope that before the next annual meeting something will be done in relation to this subject, and that the new hall in con- templation will contain a fine library and museum. The following gentlemen were then severally ballotted for and de- clared duly elected officers for the ensuing year : President, Dr. Beverly R. Wellford of Fredericksburg. 1st Vice-President, Dr. James Beale of Richmond city. 2d do. Dr. Carter P. Johnson, do. do. Recording Secretary, Dr. P. Claiborne Gooch, do. do. Corresponding Secretary, Dr. William D. IIaskins, do. do. Treasurer, Dr. James Bolton, do. do. Librarian, Dr. William J. Clark, do. do. C Dr. Chas. S. Mills, Chairman. Publication Committee, < Dr. Goodridge A. Wilson. ( Dr. Arthur E. Peticolas. After ballotting for regular members, and the reading of numerous letters of application for membership, the following gentlemen were elected honorary members :* Dr. James Moultrie, president of the American Medical Associa- tion of Charleston, South Carolina. Dr. A. H. Stevens, professor in college of physicians and surgeons, of New York city. * The constitution prohibits the election of but four honorary members at any annual meeting. 348 MEDICAL SOCIETY OF VIRGINIA. Professor Jeffries Wyman, M. D., &c. of Harvard University, Mass. Dr. George D. Gibb, F. R. C. S. I., &c. of Montreal, Canada. The following resolutions were adopted : " Resolved, That the thanks of the society are eminently due to the president and other officers for the past year, for the able and courte- ous manner in which they have discharged their respective duties. " Resolved, That the president elect be and is hereby requested to deliver an address at the next annual meeting." Notice was given that at the June meeting a resolution would be offered putting aside the balance now in the treasury, together with the initiation fees hereafter received, as a separate fund to be disposed of by the society for the general benefit, and only at its annual meet- ings. The following resolution was offered and laid on the table until the next meeting : " Resolved, That the members of this society pledge themselves not to purchase, by prescription or otherwise, of any apothecary who is in the habit of prescribing." The following resolution wras adopted, and the chair was given time to make the appointments under its provisions : " Resolved, That the president appoint committees of five on the subjects hereinafter mentioned, and that they be requested to draw up written reports on these several subjects, and present them to the so- ciety at convenience." These appointments to hold until the next annual meeting. 1st. On the present condition of medicine and the interest of the profession in the state of Virginia. 2nd. On medical education and literature, and the progress of pro- fessional and popular quackery. 3rd. On hygiene and public health, and the medical topography and statistics of Virginia. 4th. On practical medicine and pathology. 5th. On surgery. 6lh. On anatomy and physiology. 7th. On obstetrics. 8th. On materia medica and chemistry. 9th. On the indigenous botany of Virginia. 10th. On those pursuits so connected directly or indirectly with the profession as to demand its attention, such as dentistry, dispensing physic, manufacturing of instruments, apparatus, &c, &c." After a lengthy discussion on some private business, the society adjourned. The New York Medical Gazette has the following item : " Quite Interesting. — In the report of a surgical clinique of an am- bitious college in Cleveland, Ohio, recently reported, the following case is gravely published : Case 13 — A boy aged thirteen, sore thumb. Treatment — A clean rag every day for a week." EDITORIAL. 349 IBETOMUJyLi Visit to Charleston — The American Medical Association. Our late visit to Charleston will long be remembered as the most pleasant trip of our lives. We had not been in the city long enough to take a quiet stroll incognito, that we might allow first impressions to be formed independent of personal circumstances, before strangers met us as friends, and we were soon overwhelmed with those hospi- talities for which the South Carolinians are so renowned. Though the crowd induced by the State convention and the association was so great that the city was filled to repletion, yet the committee of re- ception, by its activity and energy, procured good accommodations for all who arrived. We were more fortunate than our neighbor of the Messenger, in procuring good quarters with friend Mixer of the Charleston hotel, and it would be ungrateful not to say that we re- ceived the best attention, &c. The cordial reception by the profession, and the generous and splen- did entertainment by the citizens of the 200 delegates from abroad, produced a lasting impression upon all who were so fortunate as to be present. We would like to have time and space, with the ability, to do justice to the beauties of the city, the happy and pure state of the profession, and the kindness of the inhabitants of Charleston, but we are compelled to leave this duty to some confrere who will do it better. As will be seen by the proceedings which we publish in the present Number, the association was in session four days. Much of the time was occupied in the reading of long reports of the several standing committees, which were generally able and useful documents, and which most of our readers, we hope, will read in the forthcoming vo- lume of Transactions. The abolition of these committees, and the substitution in their stead of others on special topics of general and practical interest, was a popular measure ; and it is earnestly hoped that hereafter the papers presented will be of a character calculated to raise the value and reputation of the publications by the embodi- ment of American physicians, both at home and abroad. The only other feature in the proceedings of this meeting which we will notice now, is the rejection of Dr. Drake's proposition, which, in effect, con- templates the establishment of the association permanently in the Smithsonian Institute at Washington city, and changing it into a great 39 350 EDITORIAL. National Medical Society. This favorite scheme of its very distin- guished originator seemed to meet with but little encouragement. While many would rejoice to see a national society of medicine at- tached to the Smithsonian Institute, they would be unwilling to give up the present independent organization of the association, the most beneficial influences of which are exerted by its migratory character. This was well illustrated at Charleston, and we think it will be seen and felt next year at Richmond. The adjournment of the association to meet in this city next year is an honor to the state, which we sin- cerely trust will be duly appreciated. It is now incumbent upon us to organize speedily and perfectly, if we do not, our representation will not be as large as the numbers and character of the profession in Virginia would demand. Before the meeting in May next, we hope to see the State medical society so built up in numbers and strength, that every honorable practitioner in the state may be represented through it ; and we would again urge upon our friends in the coun- try to form local societies. Where five or more are in striking dis- tance of one another, let them organize and send a delegate. We hope, too, that the Doctors in Virginia will not be outdone, either in their zeal or in their hospitality and cordiality of reception. The cen- tral position of Richmond, the season, and the growing importance of the national association, cause us to believe that there will be present at the next meeting three or four hundred delegates. We promise them a suitable reception. We commend to our readers a perusal of the paper of Dr. Houston, on the pathology of scarlatina. It is long, and the subject has already occupied much space in our journal ; but as we have published very conflicting views on this subject — some, indeed, to which we heartily dissent — and without comment, we throw this paper before the pro- fession, like the others, for what it is worth. It may be well to take this occasion to say, that we do not hold our- selves responsible for all the views promulgated through the pages of the Stethoscope. It would be truly an endless task, if not an impos- sible one, for an editor of a large medical journal to undertake to give his opinion on every view expressed by his contributors or even in his selections. If he could do so, he would assume the position of an author, and his publication would degenerate into a mere series of essays on different subjects, compiled by one man. And a journal would be worth very little if it were made up of the opinions of any EDITORIAL. 351 one man. That the value of a journal depends on the value of the matter which it contains, its independence, &c, we do not deny ; but it is the duty of an editor to throw before his readers the views of men occupying high rank as practitioners and essayists, for their judg- ment, whether they accord with his opinions or not. Then, we say, we expect to continue to publish papers, as we have done, containing doctrine which we believe is not orthodox ; but in doing so, there must always be appended a responsible name, or we shall take the liberty of expressing very freely our own opinions. Indeed, comment is a right and not a privilege, which we shall always exercise when it is deemed proper, but it would be useless if not stupid for us to express disapprobation of all the opinions of contributors, when they do not accord with our own. When an individual sends us a paper for pub- lication, he desires to lay it before his brethren for their judgment and verdict, not for ours; and it is the duty of the journalist to give an op- portunity to all for free discussion, and not to assume to carry it on himself. These remarks have been called out by a knowledge of the fact that some readers have held us responsible for the soundness of doctrines promulgated through the medium of our journal, by men of reputation and ability, and on which we did not comment. To such we say, once for all, that our pages are open for free discussion, and that we should be pleased to hear from them in it. Reviews and Bibliographical Notices. Burke's New Work on the Mineral Springs of Virginia. — " The Mineral Springs of Virginia : ivilh Remarks on their use, the Dis- eases to which they are applicable, and in which they are contra-indicated, accompanied by a Map of Routes and Distances. A New Work. By William Burke, M. D., Richmond, Va. Published by Morris & Brother. 1851. Pp. 348, 12mo." This is a neat, well-executed work, fresh from the press of Messrs. Ritchies & Dunnavant, and is wholly a Richmond production. It is due to say that it does great credit to all concerned in its issue. It purports to be a guide to the invalid in his pilgrimage to those unrivalled fountains of health, the Mineral Springs of Virginia, and as such, if it had no other merit, it is entitled to great praise and a wide circulation. In speaking of the necessity of some guide to the use of mineral waters, the author says: " Whatever scepticism may have existed at a former period among medical men as to the efficiency of mineral waters, no man, in our day, who has any claim to 352 EDITORIAL. rank as a physician, can call their powers into question ; I shall not therefore en- ter into any argument on that subject. Unfortunately, however, they are no less potent for evil than good ; and it therefore becomes my duty not only to point out the advantages that may be derived from their proper use, but also the injuries that may result from their improper prescription. Both these duties I mean to perform to the extent of the moderate ability I possess, without fear, favor or pre- judice. I have no connection or interest, directly or indirectly, with any of their proprietors, and shall, therefore, be guided in my estimate of them by my own reflections and observations, derived from an experience of many years." ******* 41 1 have touched on this subject, because I have seen persons absolutely lose all the chances of benefit from the waters for want of judicious advice. Distant phy- sicians— at least many of them — know nothing of the Virginia Springs, except as a group. Very frequently, they do not know the difference between the White Sulphur and the Red Sulphur ; and often confound the latter with the Red Sweet. When, therefore, a physician, thus ignorant of the distinctive characters of those waters, undertakes to prescribe them, he is as likely to be wrong as right; and, indeed, we see, every season, many instances of such unfortunate mistakes." ******* •' Whether he employs a physician or not, let me say to the invalid : ' Be in slow haste.' Survey the whole ground according to the suggestions I have laid before you. Do not gulp down large quantities of water to expedite a cure. It would be about as wise as the conduct of a man who eats to repletion, in order to get the worth of his money, or as that of the old negro who swallowed down all the physic left by his master lest it should go to waste." The Doctor then gives " a general prescription for invalids," in which he lays down the rules of conduct in regard to diet, exercise, the use of the waters, &c, &c, and touches lightly upon the " point of saturation" which so many persons neglect entirely. Each of the springs, analyses of their waters, the principal diseases in which they are indicated and contra-mdacsXed, their situation, mode of approach and capacity of accommodation, together with a general description of whatever is interesting about them, is taken up in regu- lar order. We have not the space to give an extended notice of the professional part of the work at present, but we find in the chapter on " diseases of the liver," the following paragraphs, in which we heartily concur : "In no disease may more be expected from change of climate and habits of life than in diseased functions of the liver, and in no region of the United States is there a summer climate more favorable than the transmontane division of Virgi- nia. Independent, then, of all mineral waters, much may be expected from visit- ing this region ; but when the agency of the greatest variety of Mineral Springs may be obtained in connection with climate, our Southern friends have induce- ments to visit Virginia which are not presented by any other region of the Union. "Now, to say that any one of the Sulphur Springs is a specific, in all varieties of functional diseases of the liver, is to display great ignorance of the action of those agents. I would desire to impress upon the reader that it is not a purgative effect that is desirable in those cases. If it were, those waters that act most freely upon the bowels would be the most prompt to relieve the disease, and Sa- ratoga water would claim preference over all other waters in the United States, in those conditions of the system ; but such is not the case. We want an agent that will, in the first place, modify the original cause of the hepatic affection, and produce thereon an alterative effect." EDITORIAL. 353 In the chapter on " phthisis," Dr. B. says : " The question may now be fairly raised, allowing the curability of consumption under the most favorable circumstances, have cases thus marked and identified by an unmistakeable diagnosis been relieved at the Red Rulphur ? I answer, without hesitation, that they have. " Since the advances in diagnosis by means of percussion and auscultation, I have examined numerous patients for signs of tubercular deposition and lesion, whom I met at the Red Sulphur, and several whom I sent thither; and although I do not claim any great skill in these methods of exploring the internal organs, I satisfied myself that there was a tuberculous condition, and 1 was nevertheless gratified by seeing many such cases receive prompt and decided relief. I trust, however, it will not be inferred that I am disposed to hold forth delusive hopes to any poor invalid who may place reliance on my opinion. I seek not to deceive a human being in this matter. I candidly acknowledge that there are annually many persons presenting themselves at the Red Sulphur, that are not and cannot be benefitted, and whom, if I could have seen them before they left the comforts of home, and the kind attentions of friends, I would have advised against the journey; — but again, I do say, that if there be hope left, it is in the water of the Red Sulphur." ****** "The principle upon which the Red Sulphur acts is the sedative principle. From whatever elements this principle has been imparted to it, it is manifest that it is the great lever by which it operates." Having previously said : " This water being manifestly narcotic, is contra-indicated in plethora, apoplexy, epilepsy, chorea, vertigo, and all diseases indicating too great a tendency of blood to the brain. In the acute stages of disease, it is decidedly injurious. In the course of my practice in the neighborhood, it was used in some cases as ordinary drinking water, in the first stages of pleurisy and pneumonia, and in bilious fever, but with invariable aggravation of the symptoms. After the inflammatory stage was subdued, and in incipient convalescence, I found it exceedingly valuable in invigorating the constitution." The author sets out by modestly saying: "My readers will of course understand that I do not attempt an elaborate trea- tise on any of the subjects discussed in this work. My highest ambition is, to throw out some hints that may serve to direct the young, inexperienced physician, or the intelligent patient, capable in some degree of treating himself — if, indeed, there be any one, professional or unprofessional, capable of managing his own case, which I very much doubt, owing to that principle of self-love, and conse- quent self-indulgence, which is inherent in man." But this book is not a mere guide to the valetudinarian. It is writ- ten in a smooth, happy style, agreeable and instructive to the general reader, and is really an invaluable travelling companion to all those who frequent the mountains of Virginia. The chapters on scenery, cli- mate, the natural curiosities, the society at the springs, and the general re- marks, are exceedingly interesting, whether the reader be stationary at home, in the railroad car en route, or in the present enjoyment of the mirth and luxury of the season at the springs. The edition must soon become exhausted, and in the next the author promises to "embody the results of his observations on the Eastern group of springs, which it has been out of his power to visit." The public as well as the pro- fession are laid under real obligations for a book of such utility, com- ing too from one so well qualified by along experience and residence 354 EDITORIAL. among the springs as Dr. Burke. It is proper to state that Dr. B. is in no manner whatever connected with any of the springs, and his ob- servations on them all are marked by a candid, fearless impartiality worthy of all comment. "Medical Delusions," by Worthington Hooker, M. D., author of " Physician and Patient," of Norwich, Connecticut. New York, Baker &f Scribner. 1851. 12mo. Pp. 105. This excellent little book has met with a favorable reception through- out the country. It bore off the Fiske prize, of the medical society of Rhode Island, for 1850, and is printed in a neat form. Its style is plain but forcible, and the work is of a popular charac- ter, and calculated to do good wherever it finds its way. After some general remarks, the author takes up the " causes and nature of me- dical delusion." The first and most potent of which is " a too ready disposition to consider whatever follows a cause as being the result of that cause." The humbugs of past and present times are then taken up, among which are the following : Bishop Berkeley's tar-water panacea, which was in great vogue from 1741 to '49, the Perkins' tractors, which origi- nated in Connecticut in the last century, and which soon came into great repute in England and other foreign countries. The various cures and preventives of hydrophobia, snake stones, all-healing balms, homoepa- thy, and such like are then considered. After shewing up the ridiculous reasoning of that school, he says : "You observe that the infinitesimal doses are proved to cure diseases precisely as Perkins' tractors, the weapon ointment, and the Bishop's tar-water, were once proved to do it. The reasoning is this : " A patient took a decillionth of a grain of oyster shell three or four times a day ; he got well : therefore the oys- ter shell cured him." Cures by charms, amulets, incantations, royal-touches, &c, &c, are shewn to be produced by mental influences. Another cause of medical delusion is "the disposition to adopt ex- clusive views and notions." Under this head the " one-idea men" get a rub. Here the author might have dilated and given the calomel pana- cea men a dose. But as he had so many such subjects to touch on, it would have been an endless task to do justice to all. " The disposition to run to extremes, to overstate truth," and the very common "disposition to theorize, instead of encountering the labor of strict observation," "fashion in diseases and remedies," both pro- fessional and popular, " and an undue fondness for new things," are EDITORIAL. 355 each elucidated in a manner characteristic of the author's mental keen- ness. In conclusion, he says: "These and other sources of error may be abandoned ; and the wide domain of medical science may, even in our day, be secured under the rule of a -pure, exact, rational and compehensive observation." There are certain subjects which occupy and excite the public mind, such as mesmerism in all its forms, the Rochester knockings, lunar influ- ences, phrenology, and such like chimeras, and which are considered so much akin to medical science, that medical men are held responsi- ble for them, or are required to combat them. Now, we quite agree with Dr. Hooker in what he says is the cure for all this sloughing about the professional body, viz : Rid them of the errors and delu- sions, educate them to observe and reason, and a healthy stale of public opinion on these subjects will soon follow. Then to accomplish the end, we want more such books as the one before us, and more such men as Dr. Worthington Hooker. " Wilson's Dissector," by Goddard." " The Dissector, or Prac- tical and Surgical Anatomy, by Erasmus Wilson, with one hundred and fifteen illustrations. Edited by Paul B. Goddard, M. D. A new and improved edition. Philadelphia. Blanchard & Lea. 1851." The numerous editions through which this book has passed in Eng- land, and the high value set upon it by the denomstrators and anato- mists, both here and there, speak highly in its favor. The new (se- cond American) edition now before us has been carefully arranged and modified in such a manner that the student, by following the or- der of parts as they are laid down, will obtain the utmost advantage which can be derived from a single subject. The number of cuts has been increased in this edition, and they are about as good as those we find in any dissector's guide ; but we find the usual fault, that they are in some cases slurred, and frequently the numbers are so indistinct that they are illegible. " Fenner's Southern Medical Reports." — " Southern Medical Reports, consisting of general and special reports on the medical to- pography, meleorology, and prevalent diseases in the following states : Louisiana, Alabama, Georgia, Mississippi, North Carolina, South Ca- rolina, Florida, Arkansas, Tennessee and Texas. To be published annually. Edited by E. D. Fenner, M. D., of New Orleans. Vol. I. 1849. New Orleans. B. M. Norman. New York. S. S. & Wm. Wood. 8vo. Pp. 472, muslin. The volume of this work already before the public fully sustains the high expectations raised by its prospectus. The character and value of the matter do great credit to the reporters and to the propri- 356 SELECTIONS. etor of the book. It is entirely what it professes to be, and the high- est commendations have been bestowed upon it by the press and the profession. The American medical association, both last year and this, adopted resolutions laudatory of the project, and recommended it to the active support of the profession. We hope that the enter- prising and gifted editor will meet with that liberal patronage which the value of these reports ought to command, and which will enable him to make it still more useful and creditable to American physicians. " It is a standard library book for every Southern practitioner" at least, and we look forward with much pleasure to the receipt of the forthcoming Volume II. History of a Case of great Distortion of the Pelvis, in which Delivery was safely accomplished by the operation of Craniotomy. By Robert Lee, M. D., F. R. S. On Friday, the 21st inst., at eleven, P. M., Mr. Dunn, of Norfolk street, Strand, requested me to see a patient with him who had been forty-eight hours in labor, and whose pelvis was distorted in a high degree. The os uteri was imperfectly dilated, and no part of the head had entered the brim of the pelvis. Mr. Dunn thought, and I agreed with him, that the distance from the base of the sacrum to the symphisis pubis could not exceed an inch and a half — in fact, that it was nearly as distorted as the monster pelvis lately exhibited at the Medical and Chirurgical society. It was believed that the patient was at the full period of pregnancy ; and in proceeding to deliver with the perforater and crotchet, I expected to encounter very great difficulty. The head was readily opened, and the brain evacuated; and on fixing the perforator on the inside of one of the parietal bones, and extracting, not very forcibly for a few minutes, the bone was de- tached from the other bones and came away. The remaining cranial bones were speedily crushed with the crotchet, the point of which was then carried outside the head, and fixed in one of the orbits. With this hold, in less than half an hour the head was extracted, with the employment of very moderate force. The facility with which the delivery was accomplished in this case of great distortion, arose from the circumstance that the labor was premature, contrary to our expectation : the foetus, instead of having reached the full period, had only reached the end of the seventh month. Premature labor, in this case, rendered the operation of craniotomy safe and easy. This patient had before been twice pregnant ; the first time the child died prematurely, and was expelled by the natural efforts, as in the famous Cupar case. In her second pregnancy, the labor was dif- ficult and protracted ; but in what manner the dead child was ex- tracted we could not certainly ascertain. The history of the preceding case illustrates in a striking manner, SELECTIONS. 357 the truth of my statements recently made to the medical and chirur- gical society respecting the Caesarian operation, and the importance of the early induction of premature labor in cases of high distortion of the pelvis. — London Lancet. Report of a Singular Case of Apoplexy. By Ezra Harle, Surgeon, Islington. On Wednesday night, January 15th, I was called to a poor " wo- man in a fit." A few minutes after she had fallen in the street, I was on the spot, and found her dead. At the post-mortem examination we found the following, as I apprehend, unusual appearances conjoined. The brain was surrounded with blood, the ventricles filled, and a quan- tity at the base — in all about four ounces. This was sufficient to ac- count for the death; but on examining the chest, we found the left lung unusually smaller than the right, marked with long-standing dis- ease, and gorged with blood, sufficient of itself to account for death, as in ordinary pulmonary apoplexy. The other viscera were healthy. The woman being of so spare habit, and about sixty-five years of age, causes the case to appear more unusual; so much so, that one can agree with the words of the deputy coroner, that " we should hardly suppose she had so much blood in her whole body." Thus proving that persons of very spare habit may be subject to sanguine- ous apoplexy. In justice to the case, it must be said, that shortly before her death she had taken a " glass of gin," on returning from her " ironing work" in her usual health. — Ibid. Case of Small-pox occurring a third time after Vaccination, when it proved fatal. — After alluding to the fact that whooping-cough, measles and scarlatina generally occur only once during the lifetime of an in- dividual, exceptions, nevertheless, to the above rule, as well in these complaints as in smallpox, have been recorded by authors. Three well-marked examples of the recurrence of smallpox, met with in the same family, are related, one of which terminated fatally. The case especially referred to by Dr. Webster was that of H. N. N , who had been vaccinated satisfactorily in 1827, when three months old. Notwithstanding this circumstance, he became attacked by smallpox in 1S33, along with an elder brother, who had been likewise vacci- nated. Both patients recovered, and nothing more was thought of the matter till 1838, when the two lads were again attacked by variola, along with another — that is, a third — brother, likewise regularly vac- cinated. However, all three got quite well in due time. Subse- quently, Mr. H. N. N , whose case is now just mentioned, went to India in the company's service, where he was seized, in April last, with the usual and well-marked symptoms of smallpox, which soon became confluent, and proved fatal at Dharwarinth, on the 13th of that month ; this making the third time this gentleman had been at- tacked by variola, although previously vaccinated. — lb. 40 858 SELECTIONS. Transfusion in Uterine Hcemorrhage was interdicted in France two years after it was first introduced by Dennis and Emerets, and at- tempts by a provincial judge were made quite recently to interfere with its performance, in virtue of the prohibition of 1668. Transfu- sion has, nevertheless, been recently performed by M. Nelaton at the Hopital St. Louis, Paris with success, though the patient died seven days afterwards of metro-peritonitis. The case was one of placenta prsevia, the os being too rigid to admit the hand, haemorrhage went on more or less for seven hours, when M. Nelaton being sent for, he suc- ceeded in turning and delivering, whilst the aorta was being com- pressed. The vein of a strong and robust young house-surgeon was then opened, and about eight ounces of blood transfused : the patient was at once freed from the choking sensation she had previously ex- perienced, and perfectly recovered up to the seventh day. — lb. On the Action of the Golden Sulphuret of Antimony. BY DR. BOECKER. The investigations contained in this essay of Dr. Boecker have been conducted with the greatest care, the author having experimented on himself with the medicine, and having carefully examined the princi- pal excretions before, during, and after its use. The examination of the urine especially furnished some interesting results. During the use of the golden sulphuret, the bowels acted regularly once a day ; but when the author omitted to take the medicine, he remained seve- ral days without a motion. Whenever the alvine evacuations were increased, the quantity of urine was diminished, particularly in its solid contents, as appears from numerous analyses which are re- corded. An interesting circumstance is, that the quantity of urine and of solid excreted matters increased with the dose of the medicine, and vice versa. It is also worthy of observation, that the fixed salts in general, as well as the salts insoluble in water, were increased by its exhibition. On the whole, it would appear from the experiments, that during its use a more rapid renovation takes place in all the organs and all the tissues. Another circumstance to be observed is, the in- crease in the quantity of sulphuric acid in the urine, which was nearly double the ordinary amount, doubtless in consequence of the sulphur in the preparation being converted into the acid, which subsequently enters into the sulphates. The author also details the results obtained from the examination of the pulmonary exhalation. During the use of the golden sulphuret, the amount of carbonic acid was increased, while it gradually diminished on discontinuing the medicine. The quantity of watery vapor, on the contrary, underwent no change. As to its action on the blood, the author found that it diminishes the amount of the solid constituents of that fluid. Blood drawn from a vein was at first black, but gradually became red when exposed to the air, and this change took place more rapidly than when the sul- phuret was not exhibited. The microscopic examination of the blood shewed that the nucleated globules visible in normal blood disappear. To recapitulate — golden sulphuret of antimony increases the secre- tion of urine and the exhalation of carbonic acid; it stimulates the SELECTIONS. OBITUARY NOTICES. 359 intestinal and cutaneous excretions as well as the secretions of the mucous membrane ; and it thus hastens the metamorphosis of the sys- tem, an effect which is even to be detected in the blood itself. — Archiv. fur Physiologische Heilkunde. — The Chemist. "Jewish Rite. — The spectacle of circumcision, performed by the gentleman who usually officiates in this city among the Israelites, was recently presented to the students of the New York Medical College in lieu of the usual clinique." Alleged Uncertainty in Medicine. — Dr. Thompson, president of the New York State medical society, in an address at the last annual meeting of the society, thus compares the medical with the other pro- fessions in regard to certainty in its results : " When compared with the other professions, its character is vin- dicated, and it rises in our estimation, for it may be questioned whe- ther the results of its practice are any more doubtful than those of the law, which also has been stigmatized for its ' glorious uncertain- ties.' In a subject like theology, which treats of man's eternal des- tiny, concurrence of opinion might be expected. Its doctrines, how- ever, find no more agreement among theologians and polemical wri- ters than do the accredited principles of medical science among well- informed and cultivated medical men. In the science of politics, in the laws which regulate the commerce and mutual intercourse of na- tions, in the systems and processes of agriculture, in the arrangement of society, and its government by laws whose principles and modes of action shall prove most successful in directing its interests and regulating its business affairs, men differ widely in their judgments and the greatest dissimilarity of opinions prevails. Why, then, amid this discrepancy of judgments and difference of opinions, should me- dicine be held up above all, conspicuous for its uncertainties, or forks lack of settled principles?" — Boston Medical and Surgical Journal. Obituary Record. Prof. John B. Beck departed this life, in the city of New York, on the 9th day of April. He was 57 years of age, and had long enjoyed an enviable position in the medical profession. We learn from the New York Journal of Medicine, that Prof. Beck occupied a profes- sional chair in the college of Physicians and Surgeons for almost 25 years. Of the distinguished ability with which he filled it, the medi- cal profession of the Union are well advised. The profession of the city of New York especially will feel the loss of Prof. Beck, but his death is a calamity to the country. — Western Jour, of Med. and Surg. Dr. Beck was the author of a valuable work on medical jurispru- dence, and a man of much scientific acquirement. Death of Dr. Morton. — It is with the deepest regret and pain we find ourselves called upon this morning to record the death of an eminent citizen, one of the brightest ornaments of Philadelphia and of 360 EXCHANGES. the country, Dr. Sam'l George Morton, who expired yesterday at his residence in Arch street, after a brief but violent illness of only three days. No man in the United States, in fact, not the bravest sol- dier or the most illustrious statesman, was better known or enjoyed a wider or more enviable reputation abroad. It is only at the hour of his death, that many, who knew Dr. Morton well, will be conscious that a great man has been taken away, and a light quenched which has long shed a common lustre upon the country and the world. [Philadelphia North American, 16th May. Dr. Morton had a wide reputation as a man of science. On the branches of comparative anatomy and physiology he, probably, had no equal in this country, and he leaves behind him many monuments of his genius and labor. Died at Airfield, in the county of Henrico, on Tuesday, May 13th, 1851, of congestion of the liver, Richard B. Gooch, Esq., who was long and favorably known to the public as the editor of the Southern Planter, was a man of fine education, of handsome talents, and of a very amiable disposition. He obtained a considerable reputation by a series of letters written during a sojourn of several years in Eu- rope, and originally published in the Richmond Enquirer. He was one of the best reporters, on the old plan of giving the spirit and sub- stance of a speaker's remarks, (an accomplishment requiring much higher mental attributes than the present system,) we have ever known. His death is much regretted by the fraternity, and by the community in which he was born and resided from his birth. He was buried on Wednesday with military honors by the artillery company, of which he had been an officer, and was an honorary member. [Richmond Dispatch. Publications Received. Skey's Operative Surgery. Cooper on Dislocations and Fractures, and Wilson's Dissector, by Goddard, from the publishers Blanchard & Lea, through Morris & Brother. Burke on the Mineral Springs of Virginia, from the author. Pharmacopoeia of the United States, from the publishers, Lippincott, Grambo & Co., through Nash & Woodhouse. Hooker on Medical Delusions, from the author. Fenner's Southern Reports, from the editor. In addition to our regular Exchanges, we have received the fol- lowing : The Dublin Quarterly Journal of Medical Science, No. XXI., Feb- ruary 1851 ; from Nash & Woodhouse ; and No. XXII., for May 1851, in exchange. EXCHANGES. 361 British and Foreign Medico- Chirurgical Review, No. XIV., April 1851 ; from the Messrs. Wood, New York. Price $ 3 per annum. Quarterly Summary of the College of Physicians of Philadelphia, Nos. I. and II. Price $1 per annum ; from Messrs. Lippincott, Grambo & Co., a cheap and valuable publication. We have not space to no- tice it more at length at present. A very interesting paper on " Rupture of the Urinary Bladder, with a table of 78 cases, by Stephen Smith, Surgeon to Bellevue Hospital, N. Y., from the author. Re-printed from the N. Y. Journal of Me- dicine. Report of nine cases of Vesico-vaginal Fistula, treated by operation, with remarks on the mode of operation, Sfc. By George Hay ward, M. D., re-printed from the Boston Medical and Surgical Journal, from the author. And from the same gentleman, " The statistics of the amputa- tions of the large joints performed at the Massachusetts General Hospital, from its establishment to January 1, 1850. General thanks are due to the compilers of these useful tables. We welcome to our list a new and very promising bi-monthly, The Nashville Journal of Medicine and Surgery, edited by Professor W. K. Bowling, of the University of Nashville. Terms $ 2 per an- num, in advance. This journal contains 64 pages, and is well exe- cuted. We observe that the editor says in his second number, that he " has still room on the subscription list for a few more names." He has grown rapidly. We have room enough on our list for a great many more names — (and by the bye we can furnish the back num- bers.)— Success to the work. The New Orleans Medical and Surgical Journal for May has come. We observe that the publisher of this journal has become involved, and that its spirited editor is now the proprietor. We hope that Dr. Hester will be much more successful in the management of his bu- siness affairs, and, judging from his editorial capacity, we doubt not that he will. The Southern Planter for May. P. D. Bernard. $1 per annum. Innumerable catalogues and medical college circulars and announce- ments (or rather advertisements) have been received. Where is the Transylvania Journal of Medicine, that we never have received it ? The last No. of Dr. PupWs New York Journal has not yet come to hand. INFIRMARY OF THE This institution, under the management of the Faculty of the Rich- mond Medical College, is open for the reception of patients through- out the year, at the following charges : Colored Patients, - - $ 4 per week. White Patients, - - 5 " For a Private Room, the charge is 7 " These charges cover all expenses for diet, nursing, medicines, me- dical attendance and surgical operations. The Infirmary was established thirteen years ago, and the success which has attended it, the benefits it has conferred on the sick, and the trifling expense at which these benefits are secured, commend it to the favorable attention of the public. The fees for the first week are required to be paid in advance. Gentle- men sending patients from a distance will please give a city reference. Attending Physicians. Profs, TUCKER, BOHANNAN and CHAMBERLAYNE. Attending Surgeons. Professors GIBSON and JOHNSON. S. MAUPIN, M. D., Pres. of the Infirmary. PURCELL, LADD & CO. DRUGGISTS, No. 92, corner of Main and 14th Streets, RICHMOND, VA. KEEP CONSTANTLY ON HAND A LARGE AND GENERAL ASSORTMENT OF FRESH AND RELIABLE DMaS, MEBIOIHUS; French, English, German and American Chemicals; Surgical Instruments, Physicians' Saddle Bags; PAINTERS' COLORS, OILS, DYE-STUFFS, WINDOW GLASS, ETC. We are careful in the selection of articles, and endeavor to offer none but those of reli" able quality and known purity. f^" Particular attention is given to the preparation and procuring of ALL NEW PHARMACEUTICAL PREPARATIONS and CHEMICALS, which are added as they are introduced so as to render our stock at all times complete and desirable. Our facilities enable us to offer to purchasers such inducements as will give satisfaction. f3F* Orders promptly and carefully attended to. mm & f qxudw, 139 MAIN STREET, RICHMOND, VA. Wtai ntmswd'Q in BOOKS, STATIONERY, AND In the department of MEDICAL LITERATURE, they devote particular attention in keeping up a full supply of the Standard Works, as well as the late publications, and offer them for sale as low as they can be had in any regular establishment in the United States. They furnish all the Medical Periodicals. j^p° English, French and German Books imported to order, with care and despatch. ■tain & BMnuBi (LATE DRINKER & MORRIS,) Wholesale Booksellers, Stationers, Publishers, and Dealers in Piano Fortes, Music, Musical Merchandise, Fancy Goods, &c, &c. 97 MAIN STREET, RICHMOND, VA., Are constantly supplied with the most important publications in every department of literature, the arts and sciences. Orders from private individuals, schools, colleges, academies, semi- naries of learning, or other public institutions for Books, Stationery, Piano Fortes, Sfc, fyc, will be furnished on the most favorable terms, and with the greatest despatch. Foreign books imported to order. PIANO FORTES. Morris & Brother are the sole agents for the sale of Worcester's unrivalled Instruments, and in evidence of their superiority beg to sub- mit to a discriminating public the following testimonial : Improvement in Pianos. — New York is fully entitled to the credit of having effected the greatest real improvements in the construction of that noblest of all instruments, the Piano- Some others may have added to the sweetness of certain parts of their instruments at ihe cost of the power and brilliancy of the whole ; while others again have lavished money upon the fantistic decorations of the frames; but to our fellow-citizen Worcester, whose Pianos have latterly made wajr so rapidly into public favor, belongs the merit of increasing at the same time the power, quality and eudurance of tone, and without a corresponding exaggeration of price. — New York Mirror. ROBERT M'NAMEE, MAKER OF #• MAIN STREET, opposite American Hotel,- Asks the attention of Physicians and Dentists to his stock, which will be found to comprise all kinds of Dental and Surgical Instruments, Trusses, Cutlery, &c. He likewise makes to order and repairs all descriptions of Instruments. Thankful for the liberal patronage he has already received, he trusts to be able to merit a continuance of it, by increased business facilities, and a determination to give entire satisfaction to his patrons. AB-ii a mm&% p APOTHECARIES AND DRUGGISTS, Richmond, Va., (SUCCESSORS TO ALEXANDER DUVAL,) Dealers in all kinds of Medicinal Preparations, English, French, German and American Chemicals of the most approved makers. Also, the well known Pharmaceutical Prepara- tions of Herring & Brothers of London, Howard & Kent, Morson and others. Surgical and Dentists' Instruments, Paints, Oils, Dyes, Window Glass, Perfumery, Brushes, &c, &c. Physicians and others may rest assured that their orders will meet with prompt attention, and be supplied with articles of unquestionable quality. PRINTING AND BOOK BINDING. ^s^sggSBggpii^a3j»3a ftW We take this occasion to inform our friends and the public, * that we have, at great expense and much labor, laid in the fullest supply of materials for executing all kinds of Promptly, and on reasonable and satisfactory terms. The new " Code of Virginia," " Stethoscope," and the " Mineral Springs of Virginia," by W. Burke, M D., present a fair specimen of the typographical capacity of our office — and we are prepared to exe- cute all kinds of work in the same style. J OS FRXNTXBT& Of every description neatly executed, in various colors, (Gold, Bronze, 8fc.) For Lawyers, Clerks of Courts, Sheriffs and Constables, printed to order. For Merchants, Clerks of Courts, &c. made to order, and ruled to any pattern. Old Books re-bound. PRINTING INK. News, Book and Job Ink of different colors and the finest quality, always kept on hand. Address RITCHIES & DUNNAVANT, Cor. Bank fylOth Sts., Richmond, Va. THE AND VIRGINIA MEDICAL GAZETTE. No. 7.1 RICHMOND, JULY 1851. [Vol. I. An Essay on Auscultation and Percussion. BY P. H. CABELL, M. D. [Published by request of the Faculty of the Medical Department of Hampden Sydney College.] Auscultation and percussion are physical means of diagnosis, which were unapplied to medicine till comparatively modern times ; but to such a degree of accuracy have they now been carried, that we are not more certain of the existence of stone in the bladder, as revealed by the sound, nor of diseased bone by the probe, nor of fracture by crepitation, than of certain internal diseases which we can neither see nor touch, by the application of these most wonderful discoveries. Wonderful, not because of their recent discovery, but because they remained so long undiscovered, by the many acute observers and pro- found reasoners who, in every age, have shed lustre on the profession. Strange, indeed, it is that this one of our five senses should have been so long overlooked in the discrimination of diseases. The an- cients, even in the days of Hippocrates, were familiar with a spe- cies of auscultation, but they applied it only to the detection of large cavities in the lung containing water, and pneumothorax with effusion. The ear was placed in contact with the parietes of the chest, and the patient at the same time strongly and suddenly shaken ; this caused a splashing sound to be heard, and was called succussion : but here, on the very threshold of this valuable discovery, they paused, and no fur- ther improvements were made till the time of Laennec. Before its introduction by him, those internal organs, surrounded by bony walls and dense fascia, were "terra incognita" to physicians, who could only extend their observations a little way into their territories, and gain a scanty amount of knowledge by examining their outlets. Since the time of Avenbrugger, the discoverer of percussion, and Laennec, of auscultation, a complete revolution has been effected in the diagnosis of diseases of the chest ; and the healthy and morbid sounds heard in the different regions have been described with so much accuracy that little is left for future observers in this department 41 362 CABELL ON AUSCULTATION AND PERCUSSION. of medicine. All persons cannot be good auscultators and percus- sorSj as all cannot discriminate accurately between slight differences in sound ; but all should persevere, tor the perception lor nice shades of sound can be improved in the same manner as the reasoning facul- ties, by practice and application. There is scarcely a disease of the body which may not have some light thrown upon its nature or ori- gin by this means of examination ; and the negative evidence is of almost as much value as the positive; for we may thus discriminate between structural and functional diseases with a degree of accuracy unattainable by any other method ; for the general symptoms of func- tional sometimes so nearly assimilate those of organic diseases, that we are involved in the greatest doubt, and frequently by thus pre- scribing in the dark do irreparable injury to the patient confided to our care. In latent diseases also it is the only means we can possibly command for forming a correct diagnosis, as we have no general symptoms to guide us, and have to rely exclusively upon our ear. The error into which Laennec fell was, in depending too exclusively on the physical signs and overlooking the general symptoms. It seems to me, this way of trusting to any one means of diagnosis is wrong ; the more light we have the better, and even with all we can procure, physical and general, we are often baffled in making out a correct diagnosis. One should be used to correct or confirm the other, and one should never be relied on when we can get both. If they coincide we are strengthened in our opinion as to the nature of the disease, but if they disagree we must re-consider our diagnosis and pronounce on the strongest side. Each organ and each part of the body has its own peculiar sound when stricken, and when this sound is altered, either in character or intensity, we have disease and a change in consistency or density of those organs situated beneath. Elastic, tense bodies, as the walls of the thorax, which are placed over the lungs, prolong the vibrations, and give a clear, resonant sound when stricken ; but those which are inelastic and contain fat and cellular tissue, cut short the vibrations and give a dull or flat sound. Some per- sons seem so loosely put together, that a morbid sound is produced ou percussion, while the tissues beneath are perfectly healthy, or there may be so much muscle, fat or areolar tissue superimposed as com- pletely to obscure the healthy sounds. In these persons it is abso- lutely necessary to employ a pleximeter, which, by firmly compress- ing the tissues, renders them more dense and better conductors of sound. We may thus percuss over the mammae of females, and the thick muscles in front and behind. The variations in sound, healthy and morbid, over the different regions will be alluded to when the special diseases revealed by percussion are mentioned. Auscultation is of the last importance in the physical examination of diseased organs. By it we learn the sounds produced by these organs in health and disease, from their motions, frictions, dilatations, and contractions ; having once learned the healthy sounds, we have a standard by which to measure any changes which may take place in their motions or alterations in their structure. Auscultation and per- cussion should never be separated from each other, but should go CABELL ON AUSCULTATION AND PERCUSSION. 363 hand in hand to the investigation of disease, one acting as a check on the other, and preventing the mistakes to which we are constantly liable when only one is relied on. Indeed, percussion is only a variety of auscultation ; for we listen to the sounds we ourselves pro- duce by striking on the chest, and the sounds are transmitted to our ear through the medium of the air instead of the stethoscope. The patient to be percussed should, if strong enough, be made to sit up in bed, or placed upon a chair in the middle of the room. If practicable we should have the part naked, or very thinly covered, and made as tense as possible ; this can be effected by position. During the ex- amination the most absolute silence must be maintained in the room, and all sounds excluded which may embarrass the physician or dis- turb the train of his thoughts. Avenbrugger made use of direct per- cussion, and struck the part to be examined with the ends of his fingers, nothing being interposed. This method had many objections, the sound being very diffused, and caused by the vibration of the greater part of the chest, and was incapable of detecting even serious alterations in limited spots, and caused considerable pain to a weak or diseased patient. All these objections were obviated by the introduc- tion of the pleximeter by Piorry, which limits the sound to the imme- diate neighborhood of the part stricken, gives no pain, and can be applied with as much advantage over the soft parts, as the abdomen, fat and muscle, as over bone. It has been constructed of wood, ivory and caoutchouc ; the last decidedly the best of the insensible plexi- meters. But the finger of the left hand is now universally employed, and has many advantages over the others; it is convex, and can be applied between the ribs, and under and over the clavicle, where it would be very difficult to place, so as to exclude the air, an ordinary pleximeter. It is composed of both flesh and bone, and therefore vibrates in unison with the thoracic walls, and does not alter the cha- racter of the sound ; and lastly, it is endowed with sensibility, and adds the tactile to the other perceptions, and can never be mislaid. In applying the pleximeter uniform pressure should be used over every part of the chest, and corresponding spots examined on each side successively ; it is wrong to examine one side before going to the other, as we thus lose in a great measure the power of comparison; and the disease is not so much detected by the positive as the relative sound, for the degree of resonance is very different in different per- sons, and what is normal in one is morbid in another. Neither should we percuss on one side while the patient inspires, and on the other during expiration ; for the degree of sonorousness depends in a great degree on the quantity of air in the lung. In eliciting the sound, the fingers of the right hand must be bent almost at a right angle, and their tips brought on the same level; then by a quick motion of the hand the blow is given, the arm and forearm remaining rigid, and the only motion taking place at the wrist joint; the points of the fingers should remain only an instant on the pleximeter, and the weight of the hand alone should be employed ; if more force is used the sound of resonance is interfered with, and percussion loses a great deal of its value in the discrimination of diseases. 364 CABELL ON AUSCULTATION AND PERCUSSION. Auscultation was discovered by Laennec in 1816, from which time he commenced a series of experiments, every trial strengthening him in his opinion as to its value in diagnosis. Post mortems were made, and the appearances found after death compared with the sounds heard before, till it has been brought almost to an exact science, and a disease can now be discriminated by an expert auscultator with a facility and precision truly astonishing to the uninitiated. Ausculta- tion has thus been placed on a foundation from which it can never be shaken, however many and manifold changes may sweep over the medical world, and Laennec's fame will remain as immovable as the science he nurtured into existence. The method employed by this great man was mediate auscultation, which has still some manifest advantages over the other method. The use of the stethoscope, how- ever, is not so easily acquired, and this may in some measure account for the general preference for the ear. The advantages of the stetho- scope are, it limits the sounds heard to those parts which lie under the instrument, which it is impossible to do in immediate auscultation, for the bones of the head (and the temporal especially, from its great density) are good conductors of sound, and convey impressions re- ceived from the surrounding parts to the ear with great distinctness, and of course confuse the auscultator. In using the stethoscope it can be applied where the ear cannot, as over the clavicle, between the ribs, &c. It is now always employed in diagnosticating valvular dis- eases of the heart, for we thus avoid the impulse, and hear more dis- tinctly the pathological murmurs ; but the instrument here used is not the ordinary stethoscope, but the flexible one of Dr. Pennock. It can be also used without offending the modesty of females, "to whose bosoms it is not always seemly to be putting our faces." In using the ear we are enabled to make a very rapid examination, and while we hear many sounds, a practised ear can attend only to the most important, and neglect the others. The same rules apply in auscultation as in percussion, in regard to the parts to be examined and the order of their examination, viz : that similar spots should be examined on each side successively, recollecting that the comparative sounds are almost of as much value as the positive. The organs which may be examined, and the sounds heard during health and dis- ease, will be mentioned fully hereafter. There has lately been invented by Drs. Cammann and Clarke, a means of diagnosis called Auscultatory Percussion. In this method, a solid stethoscope is used to convey to the ear the sounds produced by percussing in its vicinity ; the sounds heard are not merely clear or dull, as in ordinary percussion, but each organ has a sound pecu- liar to itself. Its authors claim for it the power of locating with accu- racy the various organs, even when overlaid by others ; but it can never be extensively employed, as it requires the co-operation of two persons, one to produce and the other to listen to the sound. It may probably be used to detect the presence of fracture in a superficial bone ; and from the thin and firm investment of the cranium, I have little doubt it might be made a most valuable means of diagnosis in fractures of this important part. If the ear is placed on the stetho- CABELL ON AUSCULTATION AND PERCUSSION. 365 scope and the cranium percussed, the vibrations will be conveyed along the bone, from particle to particle, till they reach the ear, through the intervention of the instrument. But suppose a fracture occurs be- tween the stethoscope and the part stricken, the vibrations on reaching the fracture will be suddenly arrested, and the sound will reach our ear changed in character ; and thus we may be enabled to detect this accident, usually so difficult of detection. In mentioning the various disorders and alterations of structure revealed by these physical signs, I think it best to arrange them all under three heads — first, the dis- eases and accompanying signs of the respiratory organs ; second, of the circulatory ; and third and last, of the abdominal. Of the first class I shall commence with the larynx, which is the most superior of the respiratory organs, and seems to act as sentinel to the lungs, and prevents the ingress of hurtful substances by suddenly closing its door against them. It is placed at the commencement of the trachea, and is the origin of vocal sounds : it is partly closed above by the vo- cal cords, which are stretched across from front to back, leaving a narrow slit between, which is overhung by the epiglottis cartilage, and through which all the air in its entrance in or exit from the lungs must necessarily pass. The larynx is lined with mucous membrane, which is continuous with that of the mouth and bronchial tubes. When unaffected by disease, a hollow, cavernous sound is heard on auscultation, and the vocal resonance loud and very distinct ; but these sounds are variously altered by disease. In acute or chronic la- ryngitis the mucous membrane is much thickened, either by conges- tion or inflammation, or effusion of serum in the sub-mucous areolar tissue. When this occurs a harsh, rasping sound is heard, and when there is much thickening of the membrane it may become whistling. The sound is produced by the air passing rapidly through this nar- rowed opening — a similar sound is also heard in stridulous laryngitis ; but here, instead of inflammation and effusion, we have spasmodic action of the little muscles which close the glottis ; it is essentially a nervous disease, caused by irritation of the peripheral extremities of the nerves which cause the closure by reflex action. There is not much difficulty in discriminating between the two diseases, as in acute laryngitis we have the character of the sound, changing from soft to harsh, and then remaining stationary till the decline of the disease ; while in stridulous laryngitis the whistling sound suddenly appears and as suddenly disappears, and is almost invariably confined to chil- dren, while the acute attacks adults. Laryngeal ulcerations, with thickened edges and warty growths, produce a snoring or sonorous sound. It is also said laryngitis, with exudation of false membranes which have become partially detached and are floating loosely in the larynx, gives rise to a tremulous, flapping sound ; but as the diagnosis of this disease can be made out by the other signs, and auscultation is very difficult to practise on the neck of a restless child, I imagine it will not be much employed in the detection of this disease. Another and the last sign I shall mention indicative of laryngeal disease, is diminution or absence of the vesicular murmur. This state of things may be caused by any narrowing of the glottis ; and conse- 366 CABELL ON AUSCULTATION AND PERCUSSION. quently a diminution of the quantity of air received into the lungs. These are all the diseases of the larynx with which I am acquainted, whose presence can be detected by auscultation. But this organ is liable to accident, and sometimes receives into its cavity foreign bodies, as beans, coins, &c. These of course cause great irritation and difficulty of breathing; they are sometimes fixed, but are most gene- rally moveable, acting as valves in allowing the ready entrance of air, but preventing its return. The ear applied over the larynx in an ac- cident of this kind, can readily detect a clacking, valvular sound, and we not only find out the presence of the body, but the exact spot for the performance of the operation for its removal, which alone can pre- vent the patient from dying of apnoaea. Before speaking of the special diseases of the lungs, it will be pro- per to mention the healthy thoracic sounds as heard on auscultation and percussion. The lungs occupy nearly all the space within the cavity of the chest, and are evenly applied on all sides to the ribs and intercostal spaces ; they are exceedingly light and spongy, being com- posed of bronchial tubes and air vessels, and are eminently calcu- lated to give a clear, resonant sound ; this, when heard through the thoracic walls, loses some of its clearness, and when heard through muscle and fat, becomes decidedly dull. Now all of the anterior and lateral parts should yield this clear, resonant sound, it being more in- tense over the sternal ends of the clavicles ; but over the dorsal and scapular regions, which have a thick investment of fat, muscle and areolar tissue, it loses its resonance and becomes somewhat dull, and inferiorly on the right side, over the region of the liver, decidedly so. The heart causes some slight dulness on the left side, beginning about the cartilage of the fourth rib, and extending inferiorly as far as the sixth ; below this the sound is frequently tympanitic, owing to the encroachment of the stomach. The heart, although a dense muscular organ, does not cause much dulness, being overlaid almost entirely by the vesicular structure of the lung. The sounds heard on ausculta- tion are these : at the junction of the clavicles with the sternum and directly over the large bronchial tubes, a blowing sound, called bron- chial respiration, is heard ; and posteriorly between the scapulae the same sound, but not so loud and distinct; frequently near the apex of the lung on the right side a like sound is produced, caused by the greater size and shortness of the right bronchus. Over no other parts but those indicated, do we in a state of health have bronchial breath- ing, but instead, a soft murmuring sound, (termed vesicular murmur.) like the sighing of a gentle wind among the leaves of a forest. This sound is more or less marked in difFerent" persons, being more distinct in children and thin, nervous people. Some persons, with perfectly heahhy lungs, give scarcely any vesicular murmur. Dr. Watson thinks they have more lung than necessary, "room enough and to spare," and consequently do not fully dilate their lungs, which dilata- tion, by causing the air to rush in and fill the vesicles, produces the sound. Bronchitis is the next disease in order, the anatomical lesion of which is thickening and congestion of the bronchial mucous mem- CABELL ON AUSCULTATION AND PERCUSSION. 367 brane, with subsequent effusion within and around them. Each of these changes gives rise to an abnormal sound. At first the mem- brane is thickened and lined with a tenacious mucus, instead of the normal secretion ; and the same quantity of air passing through these roughened and narrowed tubes on its way to the vesicles, gives rise to a sound called in the large tubes sonorous, and in the sm;i.ll sibilant or whistling rhonchus. These sounds are heard in the median line most distinctly, and diminish in intensity on either side. This state of things does not last long before effusion results, and then the dry sounds give place to the moist, caused by the passage of air through the contained liquid, and heard both during expiration and inspiration, and are called mucous and sub-mucous rales. They may also be heard at the same time with the dry sounds, the tubes being in some parts tu- mefied and congested, and in others filled with liquid effusions. There are no abnormal sounds elicited on percussion, as the lungs are as permeable to air as ever. There is another sound heard on auscul- tation, which, though of unfrequent occurrence in bronchitis, is a con- stant sequela of tubercular deposit, and should be mentioned in this place. 1 allude to dilatation of one or more of the bronchia, induced by violent coughing while the tubes are weakened by disease. The sound heard in such a cavity is called cavernous respiration, and when the patient speaks, the peculiar vocal resonance is termed pec- toriloquy ; and there is sometimes increased resonance on percussion. I have heard all of these sounds in a well-marked case of bronchitis, and where there were no signs, physical nor rational, indicative of phthisis. Emphysema is a dilatation of the air vesicles, which by decadence of their sides open into each other and form sacs, which may vary from the size of a pea to that of a pigeon's egg. These vesicles lose their elasticity, and become thickened ; the air does not freely pass in and dilate them, and in this way the vesicular mur- mur is abolished. But another sound is sometimes heard, caused by the rubbing of these dilated vesicles against the costal pleura, and is called the friction sound. It can never be confounded with the fric- tion sound of pleUritis, as in the latter there is more dulness on percus- sion, while in the former the sound is preternaturally clear. Pleu- ritis, an inflammation of the pleura, gives rise to the following sounds : If the pain is very acute the vesicular murmur will be very feeble, or entirely abolished ; but on the unaffected side we will have puerile respiration. The first effect of the inflammation is to dry the mem- brane, and the pleura being thus deprived of its natural lubricating fluid, instead of performing its lunctions smoothly and noiselessly, cause a dry, rubbing sound to be heard ; this dry state soon gives way to that of increased secretion and effusion, which soon abolishes the friction sound, by separating from contact the two sides of the pleura. Now for the first time percussion is available, which brings out a dull, and at the lower and posterior part of the chest where the fluid gra- vitates, a flat sound. The liquid continuing to increase, presses on and abolishes the air vesicles, and bronchial respiration is heard and is accompanied by that variety of vocal resonance termed broncho- phony. In some rare cases, instead of bronchophony, we have a pecu- 368 CABELL ON AUSCULTATION AND PERCUSSION. liar vibrating resonance of voice called atrophony. It is supposed, in order to produce this sound, the serum must be in a thin stratum over the lung, moderately compressing it. If the effusion goes on increas- ing, all these sounds are abolished, the lung being pressed airless back against the spine ; perfect flatness on percussion is now the only- sound heard on the diseased side ; but after the fluid has been ab- sorbed, and the pleura roughened by lymph, allowed to come toge- ther, the friction sound is once more heard, but is softer in its charac- ter, the lymph having been macerated in the contained serum for so long a time. Pneumonia is not only a very frequent disease, but is quite an alarming and fatal one, when not recognised in its very com- mencement and treated energetically ; and there are no means other than the physical to impart to us this valuable knowledge. In the very beginning of pneumonia the lung is congested, and there is ef- fused into the vesicles and intervesicular spaces a bloody serum, which by its presence causes great dyspnoea, preventing the entrance of the air and the oxygenation of the blood. This serum is not only in the vesicles, but also in the minute bronchial tubes ; and being more viscid than the ordinary secretion, causes the sides of these tubes or vesicles to stick together, which being suddenly separated by the entrance of the air in inspiration, gives rise to that peculiar crackling sound called crepitant rhonchus, which is pathognomonic of pneumonia ; during this state of engorgement nothing can be learned by percussion, as the lungs are still permeable to air, and will float on water. If the disease is unsubdued, it progresses to the second stage ; coagulable lymph is thrown out, completely filling up the ve- sicles and minute bronchial tubes, and abolishing the crepitant rhon- chus, in consequence of the fact that the air is unable to pass further the bronchial tubes. Now a new set of sounds are heard in the dis- eased lung ; whatever increases its density, augments its conducting power, and the sound caused by the passage of air through the bron- chial tubes, and which in health is marked by the vesicular murmur, is conveyed with surprising distinctness to the ear of the auscultator. This sound is called bronchial respiration, and is heard most distinctly at the posterior and inferior part of the chest. Coinciding with this sound we have bronchial resonance of voice — in other words, it seems as if the patient were speaking through a tube into our ear. This condition of the lung is called ramollisement rouge, or red hepatiza- tion, and yields on percussion a very dull sound, its elasticity being entirely destroyed. If the disease still advances, and the lymph, in- stead of being absorbed, degenerates into pus, we still have the same sounds as in the second stage, with the addition of mucous rhonchi. In some rare cases it goes a stage further ; cavities are formed, the dis- integrated portions along with the pus being expectorated, and the air passing into these cavities, gives rise to h hollow, blowing sound called cavernous respiration, and on causing the patient to speak, to pectoriloquy. During these three stages, the sound on percussion is dull over the diseased parts; on the opposite side of the chest respi- ration is performed with rapidity and noise ; one lung having to do the work of both, and seeming to complain under the double task im- CABELL ON AUSCULTATION AND PERCUSSION. 369 posed. This kind of respiration is called puerile, being constantly heard in children, even in health. Auscultation and percussion have been of incalculable value in en- abling us to detect tubercular phthisis in its earliest stages ; for it is only in its very incipiency, so to speak, that remedial agents are at all available in the arrest or cure of this dread disease. Prior to the discovery of the physical means of diagnosis, we were ignorant of its presence till hectic supervened, " and stained the cheek of that unna- tural red which autumn paints upon the perished leaf." Before al- luding to the signs by which its presence may now be detected, and its progress followed towards recovery or death, it will be proper to speak somewhat at length as to the nature of tubercular disease, and the reason for its frequent appearance in the lungs. Tubercular mat- ter seems to be owing to a perversion of nutrition and assimilation. In a healthy organization the blood must be healthy, for "the blood is the fluid body, and the body the fixed and rigid blood." Healthy blood contains of water 780 parts, of globules 141, of albumen 70, of fibrine 3, of extractive matter 6 ; this is the analysis of the blood of a male. Now that of females contains the same amount of fibrine, but is remarkably deficient in red globules ; and this may possibly account in part for the gieater frequency of this disease in the latter: for in phthisis the blood is much altered, containing fewer corpuscles but more fibrine than in health ; and this fibrine is not only increased in quantity but changed in quality; it loses its healthy plasticity, and is prone to degenerate into unorganized masses. Fibrine being the ma- terial of which the tissues are composed, is constantly being deposited and removed by the capillaries and absorbents. When first effused it is soft, and composed of fibrils and exudation corpuscles, which soon acquire a cell wall and nucleus, and afterwards undergo further vital changes, and assimilates itself to those structures it is designed to nourish. But the tubercular plasma is either cacoplastic, or en- tirely unorganizable, and when effused from the capillaries, the exu- dation corpuscles increase in size by endosmosis, till they are too large to be absorbed and eliminated in the usual way. The tissue in which this aplastic substance is effused need not necessarily be in- flamed, but its deposit is more rapid during the existence of irritation or inflammation, and for at least two reasons — first, more blood is car- ried to the part than during health, and wherever there is increased flow, there is increased deposit ; second, the quantity of fibrine in the blood is much increased by a local inflammation, the inflamed spot seeming to be the laboratory where it is manufactured in the largest quantities. Now if the blood is healthy, this fibrine will become organized and constitute false membranes, granulations, &e ; but in the strumous diathesis every effusion and deposit in the body may become aplastic, and is then subject to chemical and not vital laws, acting as irritants and causes for still further deposit. Phthisis is then a blood disease, complicated with local lesions, and it is only by restoring the normal constituents and proportions of the different elements entering into the blood, that we can hope to arrest the disease; and it is of the last importance that we recognise it in its very commencement, before the 42 370 CABELL ON AUSCULTATION AND PERCUSSION. blood has been irretrievably ruined. The first auscultatory sounds heard indicative of phthisis, are rude respiration and prolonged expira- tion. This rudeness is not removed by full inspiration nor coughing, which would be the case if it depended on inspissated mucus, and seems to be caused by the deposit of tubercular matter on and within the bronchial tubes and air vesicles ; and in the place of the smooth, polished surfaces we have in health, there is roughness and thicken- ing ; the air in passing over these roughened surfaces meets with re- sistance, and in proportion to the resistance, is the rudeness of the respiration. When the tubercle is deposited in sufficient quantities to fill up the vesicles, bronchial respiration and bronchial resonance of voice are heard ; and coincident with this sound there may be mucous and sub-mucous rales, caused by irritation, and generally commencing at the summit of the lungs, and gradually extending downwards. Slight bronchial respiration at the apex of the lung on the right side is not an abnormal sound, but when heard on the left should be regarded with suspicion. Percussion under and upon the clavicle may detect the presence of even a small quantity of tuberculous matter; for the summit of the lung is in immediate contact with that bone, and very slight dulness can be recognised. In those parts of the lung free from tubercle, the respiration is hurried and puerile, the air passing with great rapidity through the bronchial tubes. These first sounds are very difficult to recognise, but they should in suspicious cases always be sought after with care ; for the disease if not now arrested, will in all human probability proceed unchecked to a fatal termination. The lungs, of all the organs of the body, are most liable to tubercular de- posit, and when tubercle is found elsewhere we may with certainty predict its presence here; for this preference several reasons have been offered, some supposing its exceeding vascularity, and others its eliminating character to be the cause. Dr. Williams supposes the frequent deposit at the summit to be owing to the great quan- tity of lax areolar tissue found there, and between the meshes of which the tubercle is easily infiltrated. There is dulness on per- cussion generally over the clavicle, caused by the consolidation of the lung underneath ; and although this dulness may be slight if heard on only one side, it should be regarded with suspicion. If the tubercular matter increases in quantity, we soon have other signs to guide us with certainty to our diagnosis; for after a longer or shorter time this foreign substance must soften and be expelled, not by any power inherent in the mass itself, for it is not endowed with vitality, but by softening of the surrounding structures, and the bands of areolar tissue which permeate it in all directions, and between the meshes of which it is deposited; being thus softened and macerated, it finally makes its way into one of the bronchial tubes and is expelled. While undergoing the softening process a crackling sound is heard on auscultation, which, after evacuation of the matter, gives place to cavernous respiration and cavernous resonance of voice, (pectoriloquy,) while in the surrounding portions we have harsh and bronchial respi- ration, owing to the consolidation and increased conducting power of the lung, and over those parts not involved in the disease, puerile res- CABELL ON AUSCULTATION AND PERCUSSION. 371 piralion. Over the cavity the sound on percussion is more resonant than in health, and if it is large and near the surface, almost tympa- nitic or amphoric. The amphoric is only a modification of cavernous respiration, being heard in a large cavity with thick firm walls, and containing liquid ; when a bronchial tube opens below its level, gur- gling is produced, and in the adjoining ones mucous and sub-mucous rales. Now recoveiy, while extremely rare under these circum- stances, is by no means impossible ; for if we can prevent the deposit of a fresh crop of tubercles, the sides of the cavity gradually approxi- mate, contract adhesions and leave only a cicatrice in the spot for- merly occupied by the tubercle, or the more fluid parts of it being absorbed, the rest may remain a hard, chalky and innoxious mass, causing very little inconvenience to the patient. When the cavity is large, placed near the thoracic walls, and has thick but soft and flaccid sides, the sound heard on percussion is very peculiar, resem- bling very much that caused by striking the closed hands against the knee, and called the cracked pot sound. The same sound is some- times heard on percussing a healthy but thin person, with the lung full of air and the mouth open. After phthisis has existed some time, the pulmonary pleura is very apt to be perforated, and air admitted in contact with a serous membrane, causing great disturbance. The irritation set up by the presence of air soon induces an effusion of serum, (pneumothorax with effusion,) and we then have at the base of the lung perfect flatness on percussion, strongly contrasted with the tympanitic sound above. Pneumothorax, while in the great majority of cases caused by tubercular perforation, sometimes occurs as the sequela of pleuritis; for on the absorption of the effused fluid the lung sometimes does not expand to fill the void, being bound down by adhesions, and air is secreted by the membrane in sufficient quantity to fill up the vacuum ; beside the flat and tympanitic sounds heard on percussion, we have on auscultation the vesicular murmur very feeble or entirely absent. If the perforation is large, the air passes in and out with a blowing sound, (amphoric respiration,) but if small, the sound heard during full inspiration or coughing, is reflected many times in the cavity, and gives rise to a peculiar ringing noise (metallic tinkling.) Another means alluded to before as being known to the ancients (suc- cussion) may also be tried ; but as the other physical signs are amply sufficient to diagnose this complication of phthisis, this one is rarely resorted to. There are other signs indicative of this disease, but as those I have mentioned are amply sufficient to distinguish it, and as my space is limited, I shall not allude to them further. While the heart and circulatory system cannot be investigated with that degree of accuracy which obtains in the lungs, we have still had much light thrown upon their structural alterations and functional disorders by the introduction of the stethoscope ; before its discovery nearly all the disorders occurring about the precordial region were included under the comprehensive title of " heart disease ;" but the particular part affected, and the nature of the lesion remained unknown till after death ; and even now, with all the improvements of modern times, we are frequently embarrassed in making out a diagnosis, for the 372 CABELL ON AUSCULTATION AND PERCUSSION. sounds heard, both normal and abnormal, are confined to a small spot in the thorax, and frequently similar sounds are produced by dissimi- lar diseases. It is therefore indispensable, before pronouncing on the nature of the affection, to collect all the symptoms, ph}rsical, general and rational ; but in this essay 1 must confine myself exclusively to the diagnosis by the physical signs. The heart is a hollow muscular organ, whose office is to propel the blood through every part of the circulatory system; it must be evi- dent, therefore, that any derangement in the action or structure of this most important viscus will of necessity be followed by serious disturbance. It consists of four cavities, which communicate with each other, and the adjoining arteries and veins, through openings protected by valves, which in their normal condition permit the blood to pass in only one direction ; these four cavities are lined with a serous membrane, which is reflected over the valves and is continu- ous with the lining membrane of the vessels. It is contained in a fibro-serous membrane, (pericardium,) which, by giving a smooth in- vestment, facilitates its motions, but still confines it to its proper place in the chest. The position of the heart, which is ascertained by per- cussion, is from between the cartilages of the third and fourth ribs above, and from the right border of the sternum to the nipple lateral- ly ; and below it reaches to the diaphragm, on which its apex rests, and to which the pericardium is sometimes attached. In front it is overlaid by the anterior lobes of the left lung, and only comes in con- tact with the ribs at one spot. Now in health, two sounds are heard on auscultation ; first, a dull, prolonged one, which coincides with the impulse of the heart and the pulsation of the radial artery ; then comes a short period of repose, and after that the second sound, which is short and quick, and is heard after the radial pulsation ; and lastly, a long silence occurs, after which the same series is repeated. The first sound is synchronous with the contraction of the ventricles, the closure of the auriculo-ventricular valves and the impulse of the heart against the ribs ; it is supposed by some that this latter is suf- ficient to produce the sound, but this cannot be, as in pericarditis with effusion the sound is still heard, although the heart may be re- moved several inches from the ribs ; the second sound is produced by the systole of the aorta and pulmonary artery and the sudden closure of the semilunar valves. These sounds are easily recognised, and are the only ones heard in a healthy state of function or organi- zation. The diseases to which the heart is liable are, inflammations of its lining and investing membranes, alterations in its valves by nar- rowings, insufficiencies, warty growths, deposits of lymph and osseous matter, and by hypertrophy of its muscular structure. There are also functional disorders, unconnected with structural alterations, and depending on faulty innervation, or changes in the composition of the blood. In investigating the heart, the flexible stethoscope of Dr. Pen- nock should be used for many reasons. The first disease occurring in the precordial region, to which I shall allude, is pericarditis, which most generally is a sequela of acute articular rheumatism ; the fibro- serous membrane of the heart being similar to that of the joints ; CABELL ON AUSCULTATION AND PERCUSSION. 373 the disease in its progress and termination is very much like pleuritis; first dryness, then serum and liquor sanguinis. During the first stage, a dry, rubbing sound sound may be heard, conjoined with a hurried and tumultuous action of the heart; this friction sound may always be distinguished from that of pleuritis by desiring the patient to hold his breath — if from pleuritis it ceases, but is unaffected in pericardi- tis. In the second stage, the natural sounds are heard very indis- tinctly, and that of friction totally abolished, as the effusion within the sac removes the heart from its normal position ; but the feeble sound is caused, not so much by this as reaching the ear through the liquid, which does not conduct sound so perfectly as a solid body. The sounds on percussion are dulness or perfect flatness, according to the amount of the contained liquid ; the space over which this dulness is heard is pyramidal, the apex being above ; after absorp- tion of the liquid, the rubbing sound may again be heard, the mem- brane once more coming in contact ; the effused lymph is sometimes absorbed, but more frequently becomes organized, glues the heart to the pericardium, hampers it in its motions, and lays the foundation for hypertrophy and other diseases. Endocarditis or inflammation of the lining membrane is also frequently complicated with rheumatism. The products of inflammation are effused as in the other disease, but are immediately swept away in the torrent of the circulation ; and frequently the only morbid alterations found after death, are redness and thickening of the lining membrane. The lymph effused on the valves seems to be more tenacious, and soon becomes organized, and passes through the different transformations till it becomes ossific. The heart in the beginning of the disease is heard to beat with great rapidity and violence, and frequently slight dulness may be perceived over the precordial region, as in pericarditis ; but they can be easily distinguished, one from the other; for in the latter the sounds of the heart are very indistinct, while in the former they are the reverse ; but the most constant and characteristic sign is the bellows murmur, which increases and diminishes in intensity, according to the violence or rapidity of the heart's action. If the disease is not completely eradicated and the effused lymph absorbed, we have a new set of sounds produced, very different from any heard in health ; this orga- nizable lymph is either effused upon the membrane of the valves or beneath it, and as it passes through the different transformations, causes a change in the character of the sounds. In practice it is ex- ceedingly difficult to detect the particular valves affected, nor is it practically of much importance. Dr. Williams has, however, pro- posed a plan which appears quite promising, namely, to note in what direction the sounds can be longest heard ; if the murmur can be most distinctly perceived in the direction of the aorta ; the semilunar valves are most probably affected ; the same rule holds good with re- gard to the pulmonary artery ; if, however, the sounds are heard most distinctly about, the centre of the heart and decrease in intensity in all directions, the auriculo-venlricular valves are most likely diseased. This state of valvular disease sooner or later causes hyperirophy of the muscular structure, composing one or more of the cavities of the 374 CABELL ON AUSCULTATION AND PERCUSSION. heart. This hypertrophy may be of three kinds ; first, without dila- tation or contraction of the cavity: second, with contraction, and third, and most frequent, with dilatation. Dr. Clendenning believes hypertrophy to be caused by vital action in the heart itself, and not by mechanical obstruction. " I would thus," he continues, " reverse, in a great degree, the order of causation usually received, and attri- bute much of the valvular disease to inflammation, mainly induced by hypertrophy, (if we exclude rheumatism,) as a most potent predis- posing cause ;" but I believe the majority of writers consider this ex- cessive growth as the effect and not the cause of valvular diseases and obstructions. It seems reasonable that the obstacles to be over- come in the circulation of the blood being greater than in health, the propelling power must necessarily be increased, and increased nutri- tion generally keeps pace with increased function. On auscultating an hypertrophied heart, we find the first sound duller and more pro- longed than in health, and frequently fills up the period of repose be- tween the two sounds ; the heart's impulse is also heard over a larger space, but is not so suddenly and intensely produced (provided the auricles are not hypertrophied) as in a healthy state of the organ. A bellows murmur is also frequently heard during the first sound, for whatever increases the propelling power or offers resistance to the free escape of the blood, causes an abnormal sound. When the hy- pertrophy is considerable there is dullness on percussion, but here the apex of dulness is below, while in pericarditis it is above. The val- vular murmurs which generally precede and accompany this disease are caused by narrowings, insufficiencies, rigidity and ossification of the va- rious openings from and into the heart ; these sounds are harsh, blowing, rasping or sawing, according to the size of the orifice and the rough- ness of its surface ; but all the sounds resulting from valvular disease are harsh and grating in their character, which sufficiently distinguish them from those of anemia and chlorosis, which are musical. If the sounds heard coincide with the systole of the ventricles, and can be traced along the course of the aorta, the semilunar valves are most probably diseased ; if, however, the sounds are heard during the dias- tole, the cause most probably is insufficiency, allowing the reflux of blood and destroying the second sound. The auriculo-ventricular valves may give rise to morbid sounds, if heard during the systole produced by insufficiency, during the dyastole by narrowing. These sounds may also be heard double, and are generally rasping or sawing in their character and indicate grave disease ; there being narrowing of one opening and insufficiency of another, or the same opening may be both narrowed and deprived of its valves, the blood rushing in and out at each contraction and dilatation. To diagnose correctly these valvular diseases is by no means easy, and we should always avail ourselves of the signs from the general system and the radial artery, which of course I cannot allude to here. Aneurism of the aorta occurs with sufficient frequency to make it necessary to say a few words concerning the physical signs by which its presence may be recognised. It occasions a dull sound on percus- sion over those parts of the sternum naturally resonant, and on auscul- CABELL ON AUSCULTATION AND PERCUSSION. 375 tation a rough bellows murmur, occurring synchronously with the first sound of the heart and preceding a little the pulsation of the radial artery. Aneurisms of other arteries, if near enough to the surface, may be recognised in the same way. In anaemia and chlorosis the blood is much altered from its normal standard, containing fewer red globules and more water. This thin blood, circulating through the vessels, is easily thrown into vibrations, and gives rise to a bellows murmur, which may be intermittent or continuous, but is always in- creased in intensity at each systole of the heart, and is called by the French bruit de diable ; it is easily distinguished from the bellows mur- mur caused by structual alteration, in being soft, musical and tremu- lous in its character. This bellows murmur is not only heard in the arteries, but also in the veins ; and it is this which renders the sound continuous ; for if a stethoscope is applied over the carotid artery of an anaemic patient, and the jugular vein compressed, the murmur will suddenly become intermittent and synchronous with the first sound of the heart. It has been demonstrated by M. Andral, that this bellows murmur always exists when the proportion of the red globules fall below 80 parts in the 1000 of blood, the normal proportion being, for females 127, for males 141 ; and the former have a greater proclivity to this disease than the latter, which may in part be owing to the greater deficiency of globules in their blood. Auscultation has also been used to diagnose cerebral diseases ; but as the sounds heard are few in number, indicate so many and different diseases, and are by no means pathognomonic, I shall not take up the little space I have left by describing them. Auscultation of the gravid uterus has been practised with great suc- cess of late years. No other single sign of pregnancy can be relied on with certainty. But there is no sound heard in the body similar to the click of the foetal heart, and when it is once recognised all doubt as to the condition of the woman is removed. It not only informs us that the woman is pregnant, but assures us that the child is living ; and in difficult and protracted labors, if the sound suddenly ceases, we know the child to be dead, and feel less hesitancy and repugnance in performing the necessary operations for the relief of the mother. There is another sound, called the uterine bellows murmur, heard in the gravid uterus, and is produced by the blood passing through the long, curling arteries; it is also called a placental murmur, but M. Depaul asserts, "that it can be heard anywhere on the uterine walls accessible to the ear or stethoscope." It cannot, therefore, be considered a cer- tain sign of pregnancy, as whatever enlarges the uterus gives rise to the murmur, and in pregnancy the death of the foetus in no way alters or abolishes the sound. The sounds of the foetal heart are two in number, close together, yet perfectly distinct, and are said to resemble the ticking of a watch in all save the metallic sound ; they are re- peated from 120 to 150 times a minute, and become less frequent during the latter months of pregnancy. They may generally be heard after the fourth month, and M. Depaul says he has recognised them as early as the third month. When two sets of sounds are pre- sent we may diagnose twins. These sounds may be heard in the 376 MERIWETHER ON THE FIBRINE OF THE BLOOD. direction of a line drawn from the umbilicus to the anterior inferior spinous process of the ilium, and as the sound corresponds with the left scapula of the foetus, we may not only recognise the presentation, but the position of the child in utero. Percussion is the only one of the physical means of diagnosis which can be made available in investigating diseases of the abdominal organs. The spleen, liver, bladder and intestines all have light thrown upon their diseases by percussion. When the liver or spleen is en- larged their dimensions may be most accurately marked out by the pleximeter, and still better by auscultatory percussion. The intes- tines yield a dull, flabby sound when filled with fecal matter, and a tympanitic one when distended by gas. The bladder also, when filled with urine, can be recognised by its circumscribed dulness, and liquid in the peritoneal sac distinguished from ovarian dropsy, one shifting with the motions of the patient, the other remaining fixed. In physometra, percussion is one of the chief means of diagnosis; in this disease, caused by an accumulation of gas in the uterus, instead of a dull, we have almost a tympanitic sound, which is limited in extent. In hydrometra the sound is also limited, but is perfectly flat in its cha- racter. But on the whole the sounds heard in the abdomen do not indicate the nature of the disease with that certainty which obtains in the chest, and palpation is still resorted to in preference to ausculta- tion and percussion for the purpose of diagnosis. I have thus, to the best of my ability, alluded as briefly as possible to the principal dis- eases whose natures are revealed, and whose progress may be fol- lowed by means of these physical signs. I know full well I have omitted many things which strictly belong to this subject, but have preferred to mention only the most dangerous and frequent diseases, and the sounds most practically useful, to over refinement and un- pardonable length. Observations on the Fibrine of the Blood. BY WM. D. MERIWETHER, M. D. [Read before the Medical Society of Virginia at its June Meeting.] In taking a general view of the present state of pathology, we can- not fail to be impressed by the great importance attributed to altera- tions of the blood in the formation of many of the diseases with which the physician is called upon to contend. It seems to be generally admitted at the present day by the most eminent observers, that there are certain diseases which have their origin in'the blood, and which owe most of their manifestations to changes in that fluid, produced by an agent, termed virus, poison or miasm ; that others may be traced farther to the source of the blood in the processes of digestion, where vitiated matters are formed, thence thrown into the blood, and by it transmitted to various organs and tissues of the body. There are also certain other diseases known as inflammations, which at one time were supposed to have their origin MERIWETHER ON THE FIBRINE OF THE BLOOD. 377 exclusively in the solids, and in which the altered properties of the blood were disregarded or considered as secondary in effect and in importance. As an expression of the present state of opinion in relation to the causes of inflammation, I will quote the words of a distinguished lec- turer on this subject :* " We may speak much equivocally of the state of the blood itself in determining inflammations, for there can be little doubt that a very great majority of the so-called spontaneous or constitutional, as distin- guished from traumatic inflammations, have herein their origin." Again : " Morbid conditions of the blood are most probably the causes of a great majority of the so-called spontaneous local inflammations." It may be stated that in most internal affections, whether inflam- matory or not, we find the blood looked upon as containing their germ or essence. Whether the theory of blood diseases be correct or not, I think it may be safely asserted that pathology and therapeutics have been much improved by regarding the blood as the seat or starting point of numerous disorders. In fevers, for example, we no longer look upon inflammation as their cause, or even their invariable attendant, nor are vain attempts made to locate their origin in particular organs or tissues. Consequently, in the management of fevers, remedies are not directed by false theoretical views to the head or to the abdomen, but a safer and more rational treatment is addressed to the whole system, or to complications as they may arise. The results obtained by chemical analyses of the blood in health and disease have contributed to the revival of humoralist doctrines, at least by directing to the fluids the attention so long exclusively fixed upon the solids ; and though in disease the chemists are unable to se- parate or detect the subtile agents which effect changes in the fluids, yet, by demonstrating what may be called their morbid anatomy, they have greatly enlarged our knowledge of diseased products. While entertaining these opinions in relation to blood diseases, and allowing due importance to the results of chemical investigations, I do not believe that the experiments are sufficiently extended or veri- fied, to enable us to deduce practical rules for the treatment of dis- ease. I shall endeavor to prove that conclusions have been drawn from the analyses of the blood, which are not warranted by the facts them- selves, and to shew the injurious tendency of these conclusions, if fully carried out in practical application. It will be recollected, that at several recent meetings of the society, the subjects of discussion being the continued and eruptive fevers, several members expressed themselves in favor of the treatment of those diseases, by an occasional employment of blood-letting, and by the use of mercury, to some extent, in most cases ; others contended that Andral had laid down a principle which should govern us in the use of these remedies, which is, " That an excess of fibrine in the blood is the pathognomonic sign of inflammation ;" this constituent * Paget — Lectures on Inflammation. — Lancet 1849. 43 378 MERIWETHER ON THE FIBRINE OF THE BLOOD. of the blood being deficient in fevers, therefore indicating a state op- posite to that of inflammation, they argued that the remedies for in- flammation, particularly blood-letting and mercury, are contra-indicated in these diseases. It follows, of course, that when the fibrine is in excess, the anti- phlogistic treatment must be resorted to. The subject, then, that I propose to notice briefly, is the value of variations in the amount of fibrine in the blood as indications of treat- ment. As the analyses of Andral have been alone referred to in previous debates, and as they coincide in general with those of other observers, I shall confine my remarks also to this author.* Andral gives as the average amount of fibrine in health, three parts in one thousand ; three then is the figure representing the ave- rage proportion of fibrine to the other constituents of the blood in health. He describes two great classes of disease, the phlegmasia? or inflammations, and the pyrexiae or fevers ; the former characterized by an excess of fibrine, the latter by a deficiency of the same. Let us examine some of the diseases in each of these divisions, in order to determine the actual value of variations in the fibrine as guides to practice. I commence with the first — inflammations, and take as an example, Rheumatism. — There is in this disease, according to Andral, a great increase of fibrine, from eight to ten parts, which places it in the highest rank of inflammatory affections. To fulfil the indication, there should be an activity in the treatment corresponding to the high rate of fibrine ; the antiphlogistic method should be strictly enforced, and calomel and blood-letting, as promi- nent agents in this plan, should be vigorously pushed ; in other words, we have a certain disease to treat ; the blood is examined and found to contain an excess of fibrine ; therefore, the remedies for inflamma- tion must be employed to get rid of this state, or, as is said, to reduce the plasticity of the blood. This, if correct, would be a very simple and excellent method, and would save us a great deal of trouble in diagnosis, and in discrimi- nating between different kinds and degrees of inflammation ; but it is well known, that neither the antiphlogistic nor any other mode of treat- ment yet devised, will certainly arrest the progress of an acute rheu- matism ; that a large proportion of cases will not admit of general blood-letting, and that a profuse administration of mercury will not en- sure a rapid or safe termination. I do not wish to be understood as denying that the judicious em- ployment of these remedies is not the proper course to pursue, but the highest authorities will sustain me in saying, that it is not advisa- ble to push them to the extent that the violence of symptoms and the high rate of fibrine indicate. Dr. Alison says,t " that large and repeated bleedings in the com- mencement of rheumatism increase the tendency to metastasis." * Andral, Essai £>' ' Himatologie Pathologique, 1843. t Cyclopedia of Practical Medicine, vol. 2. MERIWETHER ON THE FIBRINE OF THE BLOOD. 379 More recent observers have noticed a tendency to anaemia and con- sequent valvular murmurs towards the close of rheumatism, even when no bleedings had been practised. I may also mention that repeated bleedings increase the irritability of the heart, and may thus determine an inflammation of that organ. But, let us suppose that, very properly, blood is drawn two or three times, and a correct estimate made of the proportion of fibrine at each bleeding, what is the result, only, according to Andral? That the fi- brine has increased with the disease, independently of the amount of blood abstracted, and also of the age, constitution, strength, weakness or other condition of the patient. Those who regard the increase of fibrine alone as an indication, must, in such a case, repeat the bleedings and continue the mercury, though the symptoms of the disease and the constitution of the patient prohibit the treatment — thus falling into the same error that was so frequently committed some years since, when it was customary to re- gard the inflammatory crust as an index of the amount of inflamma- tion, and to treat the disease accordingly. The principle is the same in both cases, for Andral* states, "that the inflammatory crust is a certain evidence of an excess of fibrine in the blood ;" the reason why neither can be relied upon as indicating a necessity for blood- letting, is, that the most copious and frequent bleedings will not pre- vent an increase of fibrine, and consequently its appearance as the inflammatory crust. I think, then, we may safely conclude, that in the present state of knowledge on this subject, we cannot trust to the high rate of fibrine exhibited in this disease as a guide to its treatment. In erysipelas, we have another disease characterized by a high rate of fibrine. Andral says, (92,) that "Erysipelas, however slightly acute or febrile it may be, advances with an increase of fibrine represented by the figures 6, 7." It would appear, then, that the antiphlogistic treatment is indicated in all cases ; it must also be employed indiscriminately, if we are to be guided by the state of the blood alone in this disease. Now, it is generally admitted, that this disease, particularly as seen in hospitals and large cities, does not admit of very active treatment ; that many cases require stimulants from the commencement, and that, in general, depletory measures should be resorted to with great caution. We are told by South, f that in one of the large hospitals of London, the stimulating plan is the only one employed. So far as I am in- formed, the experience of the profession generally is opposed to an active treatment of erysipelas ; but those who rely upon the state of the fibrine as an indication, must employ the antiphlogistic treatment, " however slightly acute or febrile the case may be."" A great deal is said about the plasticity of the blood, and the action of calomel in reducing this state when excessive. Let us examine the value of this opinion. Andral says, (90,) " in any inflammation of the digestive passages sufficient to excite fever, the fibrine rises to 5, 6 and 7, but never be- * Op. Cit., page 74. t ChelhiB, vol. 1. 380 MERIWETHER ON THE FIBRINE OF THE BLOOD. yond ;" he also details three cases of mercurial stomatitis, uncompli- cated by other inflammation, in which the fibrine is represented by the figures 4, 5 and 6 — thus almost equalling the highest grade in in- flammation of the intestinal mucous membrane. What reliance can be placed in an excess of fibrine, as indicating the use of mercury, when we see this remedy producing the same state of the blood that it is expected to counteract? Andral observes, (89, 90,) "that when mercury is administered to combat certain acute inflammations, it is not right to admit that its antiphlogistic action depends upon this, that it creates in the blood a disposition opposite to that which coin- cides in this liquid with a state of inflammation." Andral states, " that in the phlegmasia? there is excess of fibrine in relation to the globules ;" in anaemia an actual or relative excess of fibrine, as compared with the globules, is characteristic of the dis- ease ; the same resemblance to inflammation is found in the appear- ance of the blood — he " considers it incontestible that the blood in anaemia often presents the inflammatory crust." (54.) In phthisis, there is a constant increase of fibrine in the last stages of the disease, (168,) and again, we find the same state of the blood in the latter months of gestation. (104.) Thus we have four conditions of the system, acute inflammation, anaemia, phthisis and pregnancy, all cha- racterized by the same state of the blood — an excess of fibrine, yet it must be admitted that they require very different modes of manage- ment. I will not pursue the subject farther in this branch, for it might be shewn in any case, that an excess of fibrine affords no correct indica- tion as to the proper time for commencing or suspending the use of any remedy, nor as to the extent to which a remedy should be car- ried ; and, though we may admit that this sign, taken in connection with all the attending circumstances of a disease, is entitled to some consideration, yet, relied upon alone, as a principle applicable to all cases, it must lead to gross errors of treatment. Pyrexia. — We come next to that class of diseases said to be cha- racterized by deficiency in the amount of fibrine, the pyrexiae or fe- vers. There can be no doubt that the distinction between fevers and simple inflammations is fully recognised at the present day, as is also the difference in treatment required by each ; fevers, as a general rule, not. admitting of very active interference, though exceptional cases often occur in which it is entirely proper to abstract blood and to em- ploy other active remedies. But we are told that these measures are all contra-indicated by the state of the blood, and that the use of ca- lomel particularly, must be avoided for the same reason, i. e., a de- ficiency of fibrine indicates a state opposite to that of inflammation; therefore, in fevers, an opposite mode of treatment is required. Let us examine this subject by reference to a few well known dis- eases ; take for example, Typhoid Fever. — According to Andral, the fibrine in this disease may remain in normal quantity throughout its whole course; it may be much diminished, or it may be increased by a local inflammation. MERIWETHER ON THE FIBRINE OF THE BLOOD. 381 The excess of fibrine is found to be always coincident with a local inflammation ; both are only the effects of some unknown cause ; therefore, the increase of fibrine affords no sign, gives no warning of the approach of inflammation. Now, almost the only period in the disease when general blood-letting can be safely practised, is in the commencement ; if postponed for a few days, it will generally be in- admissible. I think a great deal of the disrepute attached to this remedy is owing to its employment too late in the disease ; in robust subjects, typhoid fever occasionally sets in with great violence, threat- ening some important organ — perhaps the head or the lungs, with in- flammation ; the timely abstraction of a few ounces of blood will re- lieve the symptoms and tend to restrict the disease to its usual dura- tion ; but an examination of the blood in this stage of formation will give us no information ; the disease is allowed to run on unchecked, until at last a low form of inflammation is established in some vital part, and at the same time an increase of fibrine is discovered in the blood ; then, when too late, at a time when stimulants are demanded, we must, to carry out the principles of those who rely upon the state of the fibrine, resort to an antiphlogistic treatment. For, if it be true that calomel and blood-letting are contra-indicated by a deficiency of fibrine, it must be equally true that an excess of the same demands the employment of those remedies. As to the use of calomel in this disease, there can be no objection, for the reason already stated, given by Andral, " that it does not create in the blood a disposition opposite to that which coincides in this liquid with a state of inflammation ;" or, as I understand it, it has not the power of diminishing the amount of fibrine in the blood. There is a certain deviation from the healthy state, which is recog- nised in the blood by a diminution of the fibrine and an elevation of the blood globules — a condition very often occurring in typhoid fever, according to Andral. (61-68.) This is plethora; but no one, I sup- pose, would treat the two diseases in the same manner. Andral at- tempts to explain the difficulty, by asserting that typhoid fever at- tacks so often persons who, by their age and constitution, are in a state of plethora. In apoplexy or cerebral haemorrhage, there is a constant diminution of fibrine, which is not increased unless inflammation is set up around the clot. The indication is, to treat the disease as we are recom- mended to treat all fevers — abstain carefully from bleeding and mer- cury, and rather administer stimulants. I will not dwell longer upon this subject, as the same observations will apply equally to all the diseases of this class. I think enough has been said to shew that it cannot be asserted as a general princi- ple, that when fibrine is deficient, blood-letting and mercury are contra- indicated. The following extract from the lecture of Mr. Paget, already refer- red to, may serve to explain why variations in the amount of the fi- brine do not afford correct indication of treatment : " The supposed increase of fibrine is ambiguous ; it may be at once an increase of fibrine and of the white corpuscles of the blood. These two constitu- 382 MARKS ON THE PREVENTION OF PITTING IN VARIOLA. ents of the blood, the fibrine and the white or rudimental corpuscles, cannot be well separated by any process yet invented ; and in all the estimates of fibrine, whelher in health or in disease, the weight of the white corpuscles is included. Now, in many inflammations these cor- puscles are increased, and we have no means of clearly ascertaining how much of an apparent increase of fibrine is really such, or how much is due to the corpuscles entangled in the fibrine." To sum up some of the reasons why a variation in the amount of fibrine cannot be relied upon as a guide to treatment : 1. It gives no warning by its increase of the approach of inflam- mation, the increase of fibrine and the inflammation being cotempo- raneous. 2. Its increase is not affected by blood-letting, and seems to be in- dependent of any state of depression of the system. 3. In the words of Andral, "I have not seen that, besides the ma- lady itself, the differences of constitution, of temperament, of age, or of sex, produce any notable modification in the elevation, greater or less, of the figure representing the fibrine, whether the subjects at- tacked by any acute inflammation were weak or strong, sanguine or lymphatic, the increase of fibrine was neither more or less consider- able."— Andral, Op. Git., p. 81. 4. A diminution of fibrine occurs in diseases otherwise totally op- posite, as in apoplexy, plethora, typhoid and other fevers. Observations on the Prevention of Fitting in Smallpox. BY JULIAN C. MARKS, M. D., OF CABIN POINT, SURRY, VA. From a profound conviction of the engaging interest and impor- tance of our subject, as well as from a knowledge of the little atten- tion which has, in many instances, been bestowed on it by the pro- fession, we are led to indulge the hope that our remarks may not be considered unnecessary or valueless. If, indeed, it be conceded, as we think it must, that the great terror and dread in which smallpox is still held by mankind are owing in a considerable degree to the un- compromising warfare which in most instances it is palpably known to wage against personal beauty, with its every seductive charm and attraction, we may, upon such grounds alone, rest our apology for these observations, since it is our purpose to present a laconic expo- sition of the remedial measures best calculated to prevent complete- ly (other things being equal) the hideous and repulsive deformity of face so much feared. In doing so, however, we pretend not to originality of discovery in this department of scientific research, but content ourselves with the hope that by discussing what has already been discovered, we may draw more closely the attention of the profession in general to this interesting subject. The deformity induced by smallpox has really been so constant, and in very many cases assumed a character so frightful that the sub- ject of its prevention has long been invested with some interest ; hence MARKS ON THE PREVENTION OF PITTING IN VARIOLA. 383 various remedies have at different times been brought to the notice of the profession, claiming to have been successfully employed for this purpose. However, three or four of them only we deem worthy of comment. Perhaps those most lauded, and which present the greatest amount of testimony in their favor, are the mercurial ointment, nit. argent, and tinct. of iodine. Their successful action in any case will depend much upon the stage of the eruption at which they are employed, to- gether with the severity and variety of the disease. It having been found that their application is attended with less certainty of success after the first or papular stage has passed, and in very severe or con- fluent cases, and vice versa. From these data we derive the following : 1st, that these remedies should be employed at the very commence- ment of the eruption, or as soon thereafter as circumstances may render their application practicable ; and 2d, that a successful issue may be more confidently looked for in mild and distinct cases than in grave and confluent ones. The fundamental principle in every case is to produce an abortment of the eruption by arresting its progress early in the disease. Of the three remedies above mentioned, the one upon which most reliance may be placed in accomplishing the end proposed, is doubtless the mercurial ointment. Indeed the weight of authority in its favor is very great. Professor J. K. Mitchell of Philadelphia, than whom we have no higher authority in the United States, says, no other remedy with which he is conversant will com- pare with it in efficacy. He used a plaster, formed of equal parts of the ointment and the semivitrified oxide of lead, (litharge,) which covered the entire face ; openings being of course left for the nose, eyes and mouth, and with the most gratifying results. The ointment has been employed, sim- ply thickened with powdered starch. A preparation made by incor- porating together twenty-five parts of mercurial ointment, ten parts of yellow wax, and six parts of black pitch, is said to be signally ef- ficacious. It has been much relied on in France. It is recommended that the plaster be removed after four or five days, as from longer continuing it an unpleasant irritation might be superinduced. Con- stitutional effects from absorption of mercury are much feared by some, but doubtless upon insufficient grounds; for should salivation be produced, it would rather be conducive of benefit than injury to the patient. The happy results which this remedy furnishes are confi- dently referred by some to a mere property of excluding the air; but the fallacy of such a deduction may be clearly and positively shewn by the fact that other remedies which exclude it equally well are in- finitely less successful. May they not, as suggested by Dr. Wood, be ascribed to the specific action of the mercury? Such would seem at least to us the only rational corollary. We may add, in conclusion of our remarks on this remedy, that in view of the mental distress which is caused the patient by the great tendency of smallpox to leave behind it unsightly pits and scars, the ready application which may be made of the ointment, and its uncommon success in prevent- ing them, we would scarcely deem a physician excusable who ne- glected to give his patient the advantages of its employment. 384 METTAUER ON MERCURIAL OINTMENT. Much difference of opinion prevails with regard to the manner in which nitrate of silver should be employed to obtain the greatest amount of benefit from it. Some lend the weight of their authority in favor of the solution, which they apply to masses of the eruption, while others, who also rank high in the profession, give a decided pre- ference to the solid stick, which is applied to each pock (after having first been opened) so soon as it becomes vesicular. We deem the latter to be the more sure and effectual mode of using it. Indeed, Dr. Wood says, when thus employed it is almost certain to arrest com- pletely the progress of the eruption, and that in a short time desqua- mation supervenes, leaving no pits. The eruption has been treated not unfrequently of late with the tinct. of iodine, and in the hands of some it has proven a remedy of no inconsiderable value. Dr. God- dard of Philadelphia made application of it in a number of cases, and with the effect of preventing the slightest deformity of face even in the severest cases of the confluent variety — while with Dr. F. Sar- gent of the same city, it had no appreciable influence on the pitting. It should be pretty freely applied over the affected surface by means of a camel's hair pencil. We may mention that sulphur ointment has also been used with some success. Professor J. K. Mitchell speaks of it in very flattering and commendable terms. It must be applied to the face several times a day. We have now finished the consideration of these reme- dies with respect to the influence they exert on the eruption ; but they are deserving attention on another account ; and here, with one or two remarks more, we have done. Inflammation and tumefaction of face are not the least distressing of the many and varied phenomena which the disease presents. Over these pathological conditions they exercise, in not a few cases, almost surprising dominion, relieving the burning and tension which are almost insupportable, by diminishing the inflammation and tumefaction. Hence it would seem that, apart from all other considerations, this alone is of sufficient magnitude to warrant their use in most cases. Preparation of Mercurial Ointment. BY JOHN P. METTAUER, M. D., L. L. D., Professor of the Principles and Practice of Medicine and Surgery in the Medical Department of Randolph Macon College, Virginia. The object of this paper is to present to the medical profession, through the Stethoscope, a short and easy method for the preparation of mercurial ointment, that will lighten the labor, facilitate the pro- cess, cheapen the cost, and enable the practitioner to have the article always fresh and pure. It has always been a desideratum with physicians residing in the country, to possess a method for the preparation of this valuable the- rapeutical agent, that would enable them to prepare it themselves, and without much time or labor ; but, by the established modes, they could METTAUER ON MERCURIAL OINTMENT. 385 not expect to do so, as the various processes generally in use require both. The very tedious method of dividing the mercury by triturating it with lard or suet, when completed, it is true, furnished an excellent ointment; but the time and labor required would generally induce a practitioner to purchase, rather than attempt its preparation himself, especially if much thronged with professional business; and frequently, too, he would dispense with it, when necessary, rather than under- take to prepare it himself. The employment of terebinthinates, bal- sams, rancid tallow, and other materials possessing irritating qualities, for the purpose of facilitating the division of the mercury, as in some of the methods now used, although they facilitated the extinguishment of the particles of mercury — and the process yields a sightly, fine- looking ointment — nevertheless it could not be used long without ex- coriating or irritating the surfaces to which applied, and was utterly unsuited, when required to be used to tender and delicate organs, such as the eyes, &c. The difficulty, too, in the preparation of the ointment might tempt to fraud, either by diluting or coloring it with black substances. A method then, as already intimated, more expeditious and easier of execution, for the preparation of this valuable therapeutical agent is a desideratum ; to supply which, the annexed formula is offered to the profession. It was communicated through the " Boston Medical and Surgical Journal" in 1835, and published in part 51, vol. 12, page 396 of that valuable medical periodical. Take of mercury, f viij. spermaceti, 1 iv. mutton suet, ? vj. lard. 1 x. The mercury and spermaceti must be united by triturating them well together in a glass or wedgewood mortar of proper size. Should the division of the mercury be slow, which sometimes will be the case when the spermaceti is dry, a small quantity of lard or sweet oil may be added merely to soften the mass. The trituration must then be continued until the globules are extinguished and the mass made to assume a uniform, smooth, blue appearance. The suet should next be added, and being well mixed, the lard can be united with ihe mass ; after which the trituration is to be continued until the ointment is formed. I have found the preparation to succeed better in dry states of the atmosphere, whether in warm or cold weather, and the reason is obvious. This process requires from 25 to 35 minutes for its completion, but more time may become necessary with an inexperienced operator.' I have often completed the ointment in 30 minutes by my watch, and never consumed more than 35 minutes. The ointment yielded is in every respect suited to the most delicate or active uses demanding it as a therapeutical agent. I have adopted the method here given for its preparation for many years, and the resulting ointment used in an extensive country practice has never disappointed me, when there was a probability it would be likely to act at all as a remedy. 44 386 pollard's cases of puerperal convulsions. The quantities here given are those which I have generally employed in my own practice, preferring to prepare only small portions at a time, to enable me to have the ointment comparatively fresh always. Believing the Boston Journal does not enjoy an extensive circula- tion in the " Old Dominion" — and I am astonished it does not, as it is one of the best periodicals in the Union — I have been induced to offer my formula for re-publication through the " Stethoscope ;" a me- dical journal which I hope every physician of Virginia will support and take, if only from state pride — but it is a journal intrinsically of much meiit — to afford Southern physicians, especially my brethren of Virginia, an opportunity of testing its utility. Prince Edward C. H., May 1851. Reports of three Cases of Puerperal Convulsions, with Remarks. BY TH. POLLARD, M. D., RICHMOND, VA. Case L— 1843, Sept. 10. Mrs. B., set. 35— Third labor. Convul- sions came on in a few hours after commencement of labor. Os uteri dilatable and pains efficient. &. vs. xxiv. Stimulating enema and cold to the head. In an hour convulsions much abated. Labor progressed, and in about an hour and a half more a healthy child was born. Case progressed favorably. Case II. — 1849, April 30. Colored woman, aet. 21 — First pregnancy. Had been in labor 10 hours. Pains decreasing. Os uteri dilatable ; head engaging the superior strait. After waiting an hour, and finding the pains had nearly ceased, administered secal. conut. in two 15 grs. doses, with an interval of 20 minutes between the doses. In about 15 or 20 minutes convulsions came on ; pains slightly increased. Vs. xxxij. Stimulating enema and purgative. In two hours convulsions somewhat abated. The head seemed slightly advancing. Head shaved and blister to the nucha. Cold douche freely used on the head. After waiting several hours more, and finding the condition of things not improved, it was determined, in consultation with a neighboring phy- sician, to apply the forceps. These having been inefficiently tried, I turned the child and delivered by the feet. At this time the pains were very feeble. During the convulsions the woman had been insensible, and most of the time comatose. After the delivery she seemed to rally, the convulsions being now very slight. But the coma supervened and she died in 18 hours afterwards. Case III. — 1850, March 8. Colored woman, aet. 23 — First preg- nancy. At the full term of pregnancy convulsions suddenly came on. Saw her in about two hours in active convulsions, with very slight labor pains. Anasarcous in lower and upper extremities, ft. Free venesection from both arms. Stimulating enema and an active pur- gative. Head shaved ; cold to the head and blister to the nape. Re- medies produced very little effect ; no hope of turning. In so desperate an emergency determined to try ergot, hoping, though scarcely believ- ing, that the uterus might respond to its peculiar influence. No effect pollard's cases of puerperal convulsions. 387 produced. The convulsions continued ; labor made no progress, and death occurred in 14 hours from the attack. Remarks. — Cases 2 and 3 were sisters — both of low stature, and plethoric habit. Case 3, had been anasarcous for some time previous to her attack — a condition which some author mentions as peculiarly predisposing to eclampsia, referring to anasarca in the upper portion of the body, which would probably indicate some remora in the venous circulation, and thus predispose to congestion about the brain. It was apprehended that the ergot might have had some tendency to bring on the convulsions in case 2 ; but when it is recollected that the ac- tion upon the womb was very small, if any at all, and that the con- vulsions persisted (in spite of the remedies) long after the ergot could have continued to have had any stimulant action on the brain, I think this apprehension may be dismissed. In case 3, the administration of the ergot may be censured, but it was a " dernier ressort." It was evident that the woman must soon perish unless some impression could be made on the os uteri, and un- der similar circumstances I should again use it. Two of the cases detailed were first pregnancies, and a large ma- jority of convulsions occur in first labors — of 114 cases recorded by different authors, 91 were first children. The pathological condition in eclampsia has not been well ascer- tained. Dr. Denman says in an examination of many women who have died of this affection, he has never seen an instance of effusion of blood in the brain, though the vessels were turgid. In all the cases the heart was found remarkably, flaccid and without a: drop of blood in auricles or ventricles. Dr. Lee records a case he examined after death, where there was nothing to account for the symptoms, but a little turgescence of the blood-vessels, not more than is seen in many who have died of disease altogether unconnected with the brain. Dr. Ramsbotham made an autopsy in four fatal cases he ob- served. In case 1, extravasation of blood was found ;. this case was referrible to injury of the head. In case 2, there was no positive de- rangement detected in the brain, except turgescence of the vessels of the pia mater. In case 3, after a minute examination of the whole brain, no positive derangement could be detected. Ini case 4, no breach of the vessels could be discovered — there was injection of the vessels of the pia mater and some serum in the ventricles. Dr. Rams- botham remarks, "the whole train of symptoms evinces considera- ble derangement of the functions of the brain and nervous system, yet after death, correspondent marks of organic disease within the brain are seldom met with. I suspect that in many instances that important organ is no otherwise implicated than through the medium of sympathetic irritation." Dr. Lee speaks of a case examined by M. Cruveilhier, in which not the slightest trace of congestion of the vessels of the brain could be detected, and of another case reported by M. Bontilleux, in which he could detect no manifest alteration within the skull. He also quotes from Dr. Collins, who says, "I con- ceive we are quite ignorant as yet of what tne cause may be ; nor could I ever find any appearance on dissection to enable me to hazard 3S8 bolton's case of still-birth. an opinion on the subject." Other cases are related by different au- thors, who affirm that an autopsy has disclosed effusion of blood within the cranium. These cases are, however, rare, and do not com- pare in number with those in which there is no manifest effusion. The prognosis in eclampsia is unfavorable. Dr. Merriman in his practice found the fatal cases to be about one-quarter of the whole number. Dr. Ramsbotham makes them in his observation more than one-third. Dr. Ingleby more than one-third. Dr. Lee one-third. Colombat puts them down at one-half. In the treatment of this disease, blood-letting deservedly holds a high rank. Though effusion does not occur in many of the fatal cases, we have every reason to believe that congestion exists in many cases. The quantity to be taken will of course depend on the plethora of the system and the condition of the circulation. In some enfee- bled, hysterical women, the remedy will not be borne. After general bleeding to a sufficient amount, cups, shaving the head, blistering, enemata and purgatives should be used. On the use of opium there is some contrariety of opinion. After the force of the circulation has been lessened by the means already indicated, or in women of not originally plethoric habit, and in those of nervous temperament, I should be disposed to try opium. It has sometimes had very good effect, though the weight of authority seems to be against its utility. Would not chloroform hold out some expectation of efficacy in these cases? After the force of the pulse has been subdued by vene- section, and in view of the want of success of the usual treatment in mnny cases, it seems to us that the inhalation of chloroform would be worthy of trial. It has been known to moderate and control the con- vulsive movements in tetanus and other diseases. Why might it not in this? If the means indicated do not put a check to the convulsions, de- livery should be effected as soon as possible. This condition is de- pendent on the frequent state of the womb, and the sooner this can be emptied of its contents the better, and we should not wait to see the effect of the bleeding, cupping, &c. where the life of the woman is endangered by the violence of the convulsions, and where the womb is in a condition for delivery. Of course, in our efforts to deliver, we must be guided by the condition of things. If the os uteri is suf- ficiently dilated we proceed to turn. If the head is sufficiently ac- cessible, the forceps should be used. If neither are admissible, the former being possibly prevented by the activity of the pains or a narrow pelvis, and the latter by the head, being too high or a narrow pelvis, perforation should be resorted to. A Case of Still-birth — Normal Respiration established in three hours and forty minutes. REPORTED BY JAMES BOLTON, M. D., OF RICHMOND CITY. Mrs. It., 25 years old, a healthy, robust Irish woman — primapara — married September 7, 1S50 — delivered of a twin May 15, 1851 — 249 bolton's case of still-birth. 3S9 days. Nothing remarkable about the birth of the first. Three or four hours after, pains being feeble, gave ergot 3 j. in three doses at intervals of 10 to 15 minutes. Vigorous, effectual pains produced in about 40 minutes after first dose. Gave chloroform partially — supply being soon exhausted, and several miles from Richmond. Second child born nearly five hours after the first. Both weakly and prema- ture. The second made no effort to cry, nor even to breathe. Blew air and sprinkled cold water upon the chest and face, without producing the slightest effect. Cleansed the mouth and nose, and enclosing them with my own lips, inflated the lungs and then pressed upon the ster- num. Used artificial respiration in this mode about 20 minutes, with- out the slightest effort at respiration or motion of any kind. The heart and cord continuing to pulsate, ordered the mother to keep as quiet as possible, in order to preserve the child's connection with her. Placenta expelled in 20 minutes, and slight spasm of respiratory muscles occurred. Removed child, with placenta attached, to a tub of warm water and continued artificial respiration. During about two hours some three or four spasmodic respirations occurred. When these efforts were occasionally suspended, in consequence of fatigue, the infant's face and lips changed to a bluish hue, and the heart's ac- tion became much slower. When they were resumed t!-ie healthy color was restored, and the heart's action increased in rapidity. The cord was several times examined and found to continue its pulsations. Spasmodic efforts at respiration gradually increased in frequency until about 3 hours and 20 minutes, when they occurred at the rate of about one per minute. In about 20 minutes more, natural respirations were established, occasionally interrupted by one of a spasmodic cha- racter, and pulsations of heart having been always preternaturaliy slow, reached their natural standard. At what time the circulation of the cord entirely ceased was not observed, but a few minutes before respiration was established, its pulsations could not be felt beyond about 3 inches from the umbilicus. Functions of respiration and circulation then established in 3 hours and 40 minutes from birth. Cord tied and severed. Child enveloped in warm flannels and dressing deferred till next day. The following manoeuvres practised with advantage while infant in warm bath, and during suspension of artificial respiration : child's breast kept covered with warm water, then suddenly elevated above its surface and cool air blown upon it. These sudden alternations of heat and cold had a powerful effect in producing contractions of res- piratory muscles when irritability sufficient. This state did not exist until about two hours after birth. When irritability sufficiently increased, same effect produced by drawing the fingers and thumb of one hind down the sides of the chest, commencing at the armpits, so as to produce gentle titillation. May 16. Seventeen hours after birth — vital functions still main- tained— but its skin has a maculated, unhealthy hue, with cool sur- face; refuses to nurse, and has been i'a(\ ; has discharged meconium; died in an hour, or IS hours from birth. 390 spencer's case of enlarged liver. Remarks. — The long continuance of pulsation in the cord shews the importance of endeavoring to preserve the placental circulation in order to sustain the heart's action. So long as circulation continued there was hope of success ; for if its co-ordinate function, respiration, were performed, independent life was certainly established through the reciprocal action of the heart and lungs. From the history of this case, it is evident that the infant must have perished shortly after birth if left to itself. Success after so long an interval should encourage the practitioner to persevere so long as a glimmering of hope remains. An Extraordinary Enlargement of the Liver. REPORTED BY P. C. SPENCER, M. D., OF PETERSBURG, VIRGINIA. Mr. , aged about 60, by birth a Scotchman, was in the habit for many years before his last illness, of complaining frequently of great general indisposition, with a gradual enlargement of the abdo- men. The bowels were in a constipated state, atiended with great uneasiness. There was occasional swelling of the feet and ankles, with inability to get. about — a scarcity of urine, and then an increased quantity, alternating. There was derangement of the heart, and great difficulty of breathing. My distinguished and excellent friend, the late Dr. T. Robinson, was his physician. From my knowledge of Dr. R.'s high personal and professional attainments, I knew that all had been done for his relief that could be done. In order to lengthen out the thread of life as much as possible, we had to per- form the operation of paracentesis abdominis, every six, eight or ten days. Very large quantities of fluid were drawn offj loaded with flocculae of an uncommon size, frequently dark or black, and of such a corroding nature as to change the color of the instruments used in the operation, and even to render some of them useless : the large- sized catheters and canulas shared the same fate. By the influence of Dr. R. permission was given tor a post-mortem examination. Post-mortem examination shewed the heart and lungs more or less diseased, and the whole of the viscera, especially the liver. Could I have preserved the liver, I certainly should have made the attempt ; for, without the fear of contradiction, it was the most remarkable organ I have ever seen. It was, without exaggeration, from three to lour times the size of the ordinary organ — -had lost its natural fhape, size and appearance, and had acquired an enormous size, singular shape and peculiar consistency. Shooting out in beautiful spires, splendidly shaped and arranged, and of various lengths, it had nearly consist- ency enough to hold them together — but mv pen fails me in the at- tempt adequately to describe this wonderful organ ; it was truly a phenomenon. REGULAR IRREGULARS. 391 For the Stethoscope. Regular Irregulars. The phrase forming the caption of this communication occurred in an extract from the Lancet copied into a former number of the Ste- thoscope. It is a very expressive title of a class of medical practi- tioners, such as Hannah More describes in the Christian Church un- der the term Borderers. They keep themselves within the ranks of the regulars, but at the same time border as closely as possible on those of the irregulars. They are very careful to do nothing which would subject them to expulsion or even to discipline, and talk very empha- tically about the importance of a rigid adherence to the code of ethics. Their uniform is made of the most showy, glittering materials. If, however, their manoeuvres be watched, they will be seen edging along very closely to the irregulars and picking off a button or so, which, when fastened on their own regimentals, is concealed from common observation by the general glare. At the same time that they are very loud in their denunciations of the artifices of the irregulars, they do not scruple to steal a little trick now and then which they may use to advantage. Dr. A. hates a Thompsonian, and despises a Homoeopath. He is very strict in his outward conduct towards a brother practitioner. If the latter, however, be a young man, he treats him with an air so com- pounded of respect and patronage, that the patient and friends give him great credit for his tenderness towards the ignorant and inexperienced youth! Perhaps the latter may be green enough to receive it in the same manner, and feel quite flattered by the condescension of one so vastly his superior in skill and station. The distinguished savan in- forms the patient and friends that the plrysieian has treated the case with a remarkable degree of skill — indeed quite as much so as if the patient hud been under his own cure! Of course they all feel quite re- lieved by this assurance, but agree that it would be safer to trust this superior skill and talent on the next occasion. Dr. A. has a patient who is rather unwell, and he prescribes a little ride and some cheerful company. A visit to a friend would be very renovating to the nervous system. A seat is offered in Dr. A.'s car- riage, and Mrs. B. is quite captivated by the Dr.'s urbanily and oblig- ing disposition. How much better to employ Dr. A. than Dr. C, who don't keep a carriage, and simply prescribes for his patients with- out adding all these little valuable courtesies Mrs. B. rides by the Dr.'s side to Mrs. D.'s, and there all the family come out to receive her. The Dr. would not go in for the world, lest he should be con- sidered as endeavoring to supplant the family doctor. However, he is duly introduced by Mrs. B. amidst many Battering remarks, and he rides off, congratulating himself on his scrupulous obscrvunce of profes- sionul etiquette. Mrs. B. finds one of Mrs. D.'s children an invalid, who has been a long time under medical treatment, and all agree that it would be best to try Dr. As skill, and turn off the old faithful family physician. Mrs. E. has been ailing a good while. Her appetite is very bad. She cannot relish anything. Dr. A. calls at 's restorative and 392 REGULAR IRREGULARS. orders some nice little nick-nacks to be sent to Mrs. E. " What a ca- pital doctor," exclaims Mrs. E., " so considerate and liberal ;" and she lauds him to the skies among her acquaintance, with a voice improved in clearness and strength by broiled patridge and fixings, &c. Mrs. F. has disordered bowels — she really cannot keep anything upon her stomach. While in this deplorable condition and disgusted with life itself, a finely-dressed servant enters, bearing a tray covered with a white napkin, and presents it, with Dr. A.'s compliments. "What other doctor," exclaims Mrs. F., "would have been so atten- tive?" Just at that moment Mrs. G. drops in to enquire after Mrs. F.'s health. The feminine curiosity of both is excited to ascertain the nature of the nicety sent by the generous and considerate doctor. The napkin is raised, and an elegant glass is disclosed, packed in crushed ice, and filled with some beverage sparkling as if fresh from a fountain. A taste proves it to be iced champaigne. " What an elegant doctor !" they both exclaim. Besides this impression, there is another very profitable one. The popular proprietor of the resto- rative and all his menials are made acquainted with the important fact that Mrs. E. and Mrs. F., &c. employ Dr. A.; and besides this, as one good turn deserves another, mine host becomes an advertiser of Dr. A. to all his customers. Mrs. H. employs Dr. A. to attend herself, and is quite captivated by a round of these pretty little civilities. Her husband requires medical attention and sends for Dr. J., and is very well satisfied with the trealment of his case. Dr. A. is informed of the fact at his next visit. Alarmed and envious at the effect of such competition, he ex- claims, " Why did you not send for me?" The next time Mr. H. is taken sick, like a dutiful spouse, he permits Mrs. H. to send for her favorite doctor. Now what would be the result if the whole medical profession were to adopt this mode of purchasing practice ? He who should degrade himself the most by playing the sycophant to his patients, and make them the most costly presents, would render himself the most popular physician. The patient would learn to set a low estimate upon pro- fessional skill, and look upon all these expensive courtesies as perqui- sites, instead of regarding the services of the physician as of far more value than the fee which is expected in return. These are a few small scraps of the worn-out regimentals of the irregulars with which Dr. A. patches his own. Unfortunately for himself, however, he gra- dually puts on so many, that at last every shred of his own flashy li- very is replaced by that of his antagonists, like the silk stocking which was darned with cotton so often, that it finally became a cotton stock- ing. He then shines out in his true livery, and is expelled from the society of those who had long suspected and now detest him. If any one shall perceive from this sketch that he is unconsciously pursuing such a course towards his own ruin, let him pause and reso- lutely determine no longer to hang about the outskirts of the regular phalanx, but take a bold, manly stand in favor of high, independent principles. X. Y. Z. EDITORIAL. 393 31BJETOM2AIL 11B 3MM©HILILAiril©TOo We comply with the request of the faculty of the medical depart- ment of Hampden Sydney College, to publish the essay of Dr. Cabell, with great pleasure. Dr. C. graduated with distinction in Richmond at the close of the last session. It is the custom of the faculty to offer a prize, of a fine gold medal, for the best essay on some selected sub- ject, given to the graduating class towards the close of the term. Pre- vious to opening the packet containing the real name of the success- ful candidate for this honor, on the last commencement day, the Dean announced to the audience that the professors had been much per- plexed to decide between the merits of two of the papers handed in — that though the medal would be awarded to another, it was incum- bent on him to say, that one signed " Stethoscope" was possessed of almost equal merit. We thought at the time that it would have been an act of charity to the audience, who were curious to know who "Mr. Stethoscope" was, as well as an act of justice to the gentleman himself, to have broken the seal and announced his real name. We are glad that it has since been done, and the author turns out to be Dr. P. H. Cabell. Though Dr. C. was not fortunate enough to win the prize, his able competition for it has won for him golden opinions from his old preceptors and the profession also. Of course nothing new could have been expected on the subject, but the paper is so well written and embodies so much of the valuable sciences of percussion and auscultation, that it not only merits publication, but it will pro- bably be more acceptable to our readers than other matter which we might give them. This thesis evinces a high talent for writing pos- sessed by the author; a talent which is too much neglected by medi- cal students and practitioners, but one almost indispensable to the ac- quisition of a wide reputation. It also speaks well ibr his alma mater, to whom may Dr. Cabell's future career do great credit. We " shall hear from him again," as Mr. Webster is said to have remarked to his preceptors when he left college. Ragland Will Case. A legal case of much interest has been going on in the superior court in this city, before Judge Caskie and a most patient jury, for the last month or two — known as the Ragland will case. As it has ex- cited general interest in a medico-legal point of view, we will make a 45 394 EDITORIAL. brief allusion to it at present, and give a detailed account of the medi- cal testimony, if it can be obtained, in a future Number. The testator was a planter of some wealth, living in the county of Louisa — his property consisting principally of land and negroes. He was a bachelor and lived aloof from his relations, and being seized with what his physicians testify to be typhoid fever, died in nine or ten days. Two days previous to his death he summoned to his bed- side several friends, with whose assistance he made the will now the subject matter of controversy. This will cuts off Ragland's relations and emancipates his slaves, and is objected to principally, we believe, upon the following grounds : That the testator, laboring under typhoid fever, was incompetent to make a will two days previous to his death. That it was unnatural and contrary to the feelings and usages of men of his character and position. That the testator was influenced by improper exertions and acts on the part of his attendants, while not in a condition, physical or men- tal, calculated to resist such influences. The chief points of professional interest were, the competency of the individual to make his will, and the correctness of the diagnosis. These, of course, were subdivided into many points by the lawyers and medical witnesses. The attending physicians, as well as a host of medical gentlemen of this city, were summoned to give testimony in the case, and their testimony was so very discordant that neither party to the suit could make much use of the evidence of their own witnesses. We were forcibly struck with some of the Utopian theo- ries advanced, and the general ignorance of the profession in affairs of medical jurisprudence. The unwarrantable license taken by the counsel in commenting, not on the theories or opinions of the doctors, but on their charac- ters, capacities, and even their very persons, cannot be too strongly rebuked, and though it were permitted by the court, it should not have been by gentlemen having a proper self-respect. However con- flicting may be the views of medical witnesses, lawyers should be made to remember that they give their opinions as opinions only, and under solemn oath, "the truth to say to the best of their knowledge and belief." Their treatment should be the more respectful on ac- count of their being to a certain extent tongue-tied, and defenceless after leaving the witness's stand. Our profession in Virginia are sel- dom called before the courts in matters of medical jurisprudence, and EDITORIAL. 395 for this reason they are less expert in protecting their reputations than in giving keen lawyers material to make display at their own expense. If it is possible to obtain the evidence in the case, we will attempt to give a summary of the testimony of each of the medical witnesses examined. The will has been sustained. From several quarters of the state, we learn that dysentery and enteritis have prevailed to a considerable extent during the past month. Quite a drought with a week of cold, fall weather was experienced about Richmond, but the reputation of the city as being one of the most healthy in the world, has not suffered as much as the unseason- ableness of the weather would have warranted. It is proper to say that the report of the presence of cholera here is entirely idle, and would scarcely need contradiction were it not possible that it may be credited by some in the country, and they thereby prevented from vi- siting the city. Cherry disease and other complaints of the season have prevailed to their usual extent, but as the public (and some of the doctors) have suffered for two years with cholera-phobia, we are ne- ver surprised to hear these cases, when violent and attended wiih great prostration, magnified into the real Asiatic. The number of practitioners in Richmond city is about one hun- dred, and as an impression is abroad that there is " a fine opening" here, the immigration is still going on. The population of the city is about thirty thousand — the estimate then is one physician for every three hundred souls. Pretty good this, for a city the bills of mortality (if any could be made) of which would compare favorably with any city in the Union. Useful Articles. We call the attention of physicians to the Extracts prepared by Messrs. Tilden & Co. (See advertising sheet.) After a considerable trial, we feel warranted in recommending them to the profession, espe- cially in the country, as pure and reliable. We have seen in most of our exchanges the highest testimonials in their favor, and doubt net but that they need only be tried to be generally used. We will take plea- sure in furnishing samples from the lot which was sent us by Messrs. Purcell, Ladd & Co., the agents in this city, to any of our country friends for trial. They may be procured from the agents in bottles containing from % 1 to 1 ft. 896 EDITORIAL. Our thanks are due to Messrs. Purcell, Ladd & Co. also for a fine sample of Mexican or Chia seed. They are imported from Mexico, where they are used, we learn, with success in the treatment of the diseases of the bowels incident to that warm climate. They are re- commended as a substitute for bene leaves, and are very useful for the ready preparation of a bland and very abundant mucilage — a sin- gle teaspoonful stirred in a glass of cold water will form in a few mi- nutes an excellent mucilage. We have used them with great satis- faction in irritation of the bladder as well as in infantile diseases. From their cheapness, and the facility with which they are used, they are already in high repute in this city. They should be kept in every family as well as by physicians. Editor's Table. In addition to our regular exchanges for the month, we have re- ceived the usual number of pamphlets and catalogues. It is a joyful reflection, that hereafter under the new law, we shall receive these things free of postage. From the pile before us, we select the follow- ing as demanding some notice : The forty-fourth annual circular and catalogue of the Medical Depart- ment, University of Maryland. This catalogue exhibits ISO matricu- lates for the past session, of whom 72 were graduated. Appended is a short statement of the fees, statutes, &c. of the institution, and the rest of the pamphlet is the annual circular, which purports to be an expose "of the views of the faculty on the subject of medical educa- tion." This circular, like most others from faculties, abounds in good recommendations, and "earnestly urges" many things which the pro- fession would be glad to see required. The school from which it ema- nates, is one of rank, possesses many advantages, and is in a pros- perous condition. By the catalogue of the Medical College of the State of South Carolina, we observe that the class of the past session numbered 230 — a very great increase upon that of previous years. Of these, sixty-five were graduated, and all but two are marked as having received "literary educations " or collegiate degrees. Among the requirements of the candidates for graduation one is, "that they have studied medicine for three years with some respectable practitioner and then attended two full courses of lectures." By the stand which this institution has taken, it has commanded the support of the state and thus greatly in- creased its own prosperity. EDITORIAL. 397 Catalogue of the Medical Department Hampden Sydney College, Richmond, Virginia, Session 1850—51, and announcement of Session 1851-52. The summary of this catalogue shews the number of matriculates to have been 90. From Virginia 78, North Carolina 6, Mississippi 2, Alabama, Maryland, Tennessee and Ohio, 1 each. The number of graduates was 26. The announcement of this school shews that it has been steadily on the increase, and is now in a prosperous condition. The faculty, in their circular, state that " this success has been achieved in the face of many prejudices and adverse circumstances — that it was esta- blished by private enterprise, but now the state has taken the institu- tion under its fostering care, and by efficient pecuniary aid has placed it on a secure foundation, the faculty stands pledged to the public," &c. We are glad of this ; but we take the liberty, as a public jour- nalist, to make a remark or two in regard to the circular and the col- lege. It is well known that more than a year ago the legislature virtually made a donation to the medical faculty of the college of some $30,000. This measure was not universally popular for many reasons, but it is needless to enter into them here, as we believe there have been no complaints made of the act since its passage. The college is now one of the public and endowed institutions of the state, and there is a general feeling not of "prejudice," &c, but one of good will to- wards it, and a desire to see it built up into a great institution, worthy of the metropolis of the state, is generally entertained. But, for the institution to prosper and enjoy the good will and assistance of the profession at large, the faculty who now literally own it, must hearken to the wishes of the profession in regard to its management. There is no better opportunity than that now offered, for this institution to become permanently established and to take rank in numerical strength and character as one of the largest and principal schools of the United States. The profession is determined to effect a radi- cal reform in its constitution, and it seems plain to us that it is the inte- rest of the schools to take the lead in this great movement, and not wait to be dragged and cuffed into it. The rapid multiplicity of the doctor manufactories throughout the land makes it necessary for those schools which can afford to do their duty to do it at once. All the upstart schools which are spreading heresy and humbuggery, and poisoning the public mind and body, are the offspring of the old ones. The regular and legitimately organized colleges will continue to sprout these fungi and encourage their growth as long as they continue to 398 EDITORIAL. turn out ignorant, unqualified and unprincipled prostitutes of the once honorable and meaning title of doctor in medicine. The remedy is plain and simple. The faculties must refuse to admit to their lectures men who do not give entire satisfaction of their being sufficiently in- telligent and well educated to understand them, as well as of moral character enough not to pervert them. The standard of medical know- ledge necessary to obtain the title of M. D. must be raised to a de- gree infinitely above that which now enables the schools to turn them out like the factories do spools of cotton. Then the ceremony of li- censing practitioners of the " science of life," with the imposing and once respected diploma, must be made one of serious and impressive importance. Before a school should allow its graduates to receive its diploma, they should be required to swear to protect its honor and character, and to comply with all the requisitions, both moral and professional, of a high and honorable pursuit. Lawyers, and persons of much less responsibility, are required to be sworn to do their duty in their professions before entering upon the active practice of them. Had this been required of the doctors, what a different spectacle would the profession of medicine now exhibit? What a different position would the science occupy ? But to return to our subject, from which we may seem to have irrelevantly digressed. The Richmond school is one which we believe inculcates as high a professional tone as any other, and we have never heard of any of our brother alumni who have aided or encouraged in the perversion of their calling. "We think we can speak for the mass of the medical men in Virginia and North Carolina, and say that they are ready to do all in their power for the promotion of the interests of the college. But the college has much to do for itself — now, that its position is such that it can afford to take a firm stand, we call upon it to carry out the wishes of the profession, as expressed repeatedly in the national association and otherwise. Let this Virginia institution take the lead in the movement of reform, and its position will command the respect and support of the Southern profession to such a degree that its prosperity will soon be envied by its present rivals, and they will follow its good example. In regard to the announcement of the coming session, we most re- spectfully suggest to the faculty that it contains one very objectionable character. We allude to the publication of an imposing list of sur- gical cases and operations treated at the college infirmary during the past year. Whilst we are fully aware of the absence of all desire on the part of the faculty to build up their private and individual in- terests by this method of advertising, and believe them to be gentle- EDITORIAL. 399 men of too high a sense of honor to be guilty of the slightest violation of ethics, still we know that the system is distasteful to a large por- tion of the profession, and not viewed in a friendly spirit by some. The intention of the faculty in publishing the surgery cases done at the college is to advertise the infirmary more favorably to the public, and to give evidence to students of the advantages held out by the institution for clinical instruction. This we know is the sole object, but with due deference we submit our belief that this object would be achieved equally well by announcing the fact of a large number, or even the number of operations dune. It is the effect of this adver- tisement which is complained of — and the effect is very prejudicial to private practitioners. They are not allowed by any code of medical ethics, or public opinion, to do the same thing, and may complain of it with great justice. Of course, the position of the occupant of a professional chair gives an individual great advantages in private practice ; but when, in addition, he has the privilege, denied to all others, of publishing his cases to the world, he must necessarily in- crease his private practice and reputation at the expense of others, however worthy and competent, though humble, they may be. It is the duty of medical schools to publish their cliniques whenever any- thing worthy of notice occurs, and the Medical Journals afford every facilit}7 to them to do so, and are the surest media for making and ex- tending reputations both for colleges and professors. We trust that our friends of the college will not take umbrage at the remarks which this lusus on their part has called forth. We mean them in the best spirit, and are prompted to make them by an earnest desire to call the attention of the faculty to a matter which we know to be ope- rating against them. This same thing has been done before, and by schools of high fame, but the profession, through the press, complained of it, and it is discontinued. We hope it may be here. Several addresses to graduating classes have been received, among which are those of Dr. A. Litton, professor of chemistry and phar- macy in the St. Louis university, and Dr. C. Todd Quintard of Ros- wel, to the graduates of the medical college of Georgia, each abound- ing in fine sentiment and elegant conception. 400 EDITORIAL. In addition to the Exchanges heretofore announced, we acknowledge the following : The Transylvania Medical Journal. The New York Scalpel for May. The Southern and Western Masonic Miscellany, an excellent 32 page monthly, at $2 per annum, valuable to the craft, and edited by our very worthy companion and confrere, Albert G. Mackey, M. D., of Charleston, S. C, a man of great literary and masonic reputation, and a number of outside Journals. Several of these are published in Cin- cinnati, which city we have always regarded as the hot-bed of quack- ery. The Cincinnati Journal of Homoeopathy, and The Psyco-Medical and Surgical Journal, are two Cincinnati productions, each edited by sundry M. D. Professors, who are doubtless apostates, and disgraces to some of our respectable schools where they have obtained diplo- mas by the loose and culpable system of medical education, now so general. But we must be cautious or our personal safety, if ever we chance to be in Cincinnati, may not be sure, as suits for libel are the go now. Among the numerous pamphlets with which we are flooded, there are some very funny ones, such as " The Rights of Women" — " The Practice of talcing Blood in Diseases — contrary to common sense, to ge- neral experience, to enlightened reason, aud to the manifest laws of Divine Providence" ! ! With sundry scriptural quotations, certificates of M. D.'s, and a serious petition to the legislature of New York to make venesection a penal offence, attached — By Wm. Turner, M. I). This fanaticism doubtless will soon receive the sanction and en- couragement of many of the whining, shaved head Reverend gentle- men, who are not slow to depart from their sphere to adopt and en- courage all of the heresies of fools and knaves. We will notice in our next a pamphlet which has been very gene- rally circulated on Cures and the Therapeutics of Mineral Waters in ge- neral, by Rev. T. Slringfellow. II^p0 Notices of Skeifs Operative Surgery, ChurchilVs System of Mid- wifery, The Pharmacopoeia of the United States, Wilson's Dissector and Cooper on Dislocations and Fractures, have been crowded out of ihe present Number, but they shall appear in our next, when we shall also take pains to improve the department of selections in a practical point of view. MEDICAL SOCIETY OF VIRGINIA. 401 Omission. We omitted to state in our report of the proceedings of the National medical association, that the annual prize for the best essay " on phy- siology or medical chemistry," was awarded to Dr. John C. Dalton, Jr., of Boston. His subject was Ovology, and his treatise is spoken of as a very brilliant production. It will appear, by special vote, in the forthcoming volume of the " Transactions of the Association." We observe by the Buffalo Medical Journal that the Transactions of the New York State medical society are published as a document of the legislature — thus placing them in the hands of every practi- tioner, and giving them otherwise a general circulation. They make up an octavo volume of two hundred and forty-eight pages, and em- brace much valuable information. Medical Society of Virginia — June Meeting. Dr. James Beale, 1st vice-president, in the chair. Present — thirty members and several visiters. After the reading of the minutes, the following gentlemen were se- verally ballotted for and admitted members of the society: M. H. Houston, M. D., of Wheeling, Va. John G. Skelton, M. D., of Powhatan county. Carthon Archer, M. D., of Henrico county. Frank Powell, M. D., of Middleburg, Va. H. Tatum, M. D., of Chesterfield county. A number of letters of application for membership were read, the nominations seconded, and laid over for a month under the rule. The subject of the evening being in order, Dr. Meriwether pn> ceeded to read an essay " on the fibrine in the blood." (This paper is published in the original department of the present Number.) A few observations were made on the paper by several gentlemen-^they regretted, however, that the exact subject of the essay had not been made more generally known previous to the meeting, and a motion prevailed adjourning the subject over until the July meeting. Dr. Meriwether stated that his object in presenting the paper was to draw out a continuation of the very interesting discussions recently held in the society in regard to the condition of the blood in certain diseases. He desired to hear a fuller debate on this point, and acqui- esced in the desire to defer it until the next meeting. The committee for auditing the accounts of the treasurer reported that they were correct. The treasurer then presented a financial es- timate of the liabilities and necessary expenditures for the ensuing year. The following resolution was adopted : Resolved, That the assessment of each resident or attending mem- 46 402 AMERICAN INSANE INSTITUTIONS. ber for the current or fiscal year be fixed at $5 — $3 to be payable to the Richmond library association, and $ 2 to the treasurer of the so- ciety. Dr. Bolton remarked that this society being now engaged in car- rying out its original design, the organization of the profession of the state, and non-residents of Richmond justly objecting to the applica- tion of their contributions to purely local objects, he therefore offered the following resolution; Resolved, That the treasurer be directed to invest that portion of the balance in the treasury which has been derived from initiation fees during the past year, together with all other funds which may hereafter accrue from the same source, to be used by the society for the general benefit. Adopted. In view of increasing the library, Dr. Clark offered the following resolutions, which were adopted : Resolved, That voluntary contributions from members of the society to the library, with the privilege of withdrawal, be invited ; and that in all other respects the laws now in operation in respect to the library remain in force. Resolved, That the corresponding secretary be instructed to sub- scribe to the publications of the Sydenham society. On motion of Dr. M. P. Scott, the following resolution was adopted : Resolved, That a standing committee of five be appointed by the chair to investigate and report on the subject of the mineral waters of Virginia, and that Dr. Wm. Burke be its chairman. On motion of Dr. C. S. Mills, the resolution offered by Dr. Be ale at the last meeting, in regard to apothecaries who are in the habit of prescribing, was deferred until the next meeting, with the understand- ing that it shall be taken up as the first business of the evening. Dr. Gooch said that he had been using pretty extensively Tilden Sf Co.'s Extracts, and had found them very efficacious and valuable. He offered to furnish small quantities to any gentleman who might desire to use them with his indigent patients. After the transaction of sundry other business of local and private snature, the society adjourned. Proceedings of the Sixth Annual Meeting of Medical Superin- tendents of American Institutions for the Insane. The association of medical superintendents of American institu- tions for the insane, convened at the hall of the American philosophi- cal society of the city of Philadelphia, on the 19th day of May 1851, at 10 o'clock, A. M. The following gentlemen were present: Dr. Isaac Ray, of Butler hospital for the insane, Providence, Rhode Island. Dr. N. Cutter, of Pepperill (private) institution, Mass. Dr. John S. Butler, of the Connecticut retreat for the insane, Hart- ifcrcL AMERICAN INSANE INSTITUTIONS. 403 Dr. N. D. Benedict, of the New York State lunatic asylum, Utica. Dr. C. H. Nichols, of the Bloomingdale asylum, near New York. Dr. H. A. Buttolph, of the New Jersey State lunatic asylum, Tren- ton. Dr. T. S. Kirkbride, of the Pennsylvania hospital for the insane, Philadelphia. Dr. Joshua H. Worthington, of the Friends' asylum for the insane* Frankford, Pa. Dr. William S. Haines, of the Philadelphia lunatic asylum, Blockley. Dr. John Curwen, of the Pennsylvania State lunatic asylum, Har- risburg. Dr. John Fonerden, of the Maryland hospital, Baltimore. Dr. S. Hanbury Smith, of the Ohio lunatic asylum, Columbus. Dr. J. W. Parker, of the South Carolina asylum, Columbia. Dr. R. J. Patterson, of the Indiana hospital for the insane, Indian- apolis. Dr. J. M. Higgins, of the Illinois hospital for the insane, Jackson- ville. Dr. Pliny Earle, late of Bloomingdale asylum, New York. Dr. Smith, of the Missouri hospital for the insane, Fulton. In the absence of the president and vice-president, the association was called to order by the secretary, Dr. Kirkbride, and on motion of Dr. Fonerden, Dr. S. W. Parker, of South Carolina, was appointed chairman pro tern. The minutes of the preceding meeting having been read, on motion of Dr. Fonerden, it was Resolved, That a committee be appointed to select the names of in- dividuals to fill any vacancies which may exist in the offices of the association. Drs. Fonerden, Worthington and Hanbury Smith were appointed the committee. A letter from Dr. W. M. Awl, of Ohio, was read, in which he ten- tered the association his resignation of the office of president, which was accepted, and referred to the committee to nominate officers. On motion of Dr. Kirkbride, it was Resolved, That the members of this association, in receiving the re- signation of Dr. Awl, as its presiding officer, cannot allow the occa- sion to pass without testifying their full appreciation of his efforts as one of the original promoters of this association, and of his varied and important services in the cause of the insane, — and their regrets are increased by the knowledge that impaired health should have compelled him to cease to occupy the post of active usefulness in which he has been so long and so favorably known. Resolved, That the secretary be instructed to furnish Dr. Awl with a copy of these resolutions. The committee to propose names to supply vacancies in the offices of the association, nominated Dr. Luther V. Bell, of Massachusetts, as president, in the place of Dr. Awl, resigned, and. Dr. Isaac Ray, of Rhode Island, as vice-president, in the place of Dr. Bell, nominated 404 AMERICAN INSANE INSTITUTIONS. for president, which nominations were confirmed by the association, and these gentlemen duly appointed. On motion of Dr. Butler, it was Resolved, That each member be authorized to invite such indivi- duals as he may think proper, to attend the meetings of this associa- tion. On motion of Dr. Kirkbride, it wa9 Resolved, That, as heretofore, a business committee, consisting of three members, be appointed, who shall report, each morning, what papers will be read, and what other business is likely to come before the association during the day. The secretary read a letter from the late president of the associa- tion, announcing the subjects selected by him on which the members are expected to report during the present meeting, in compliance with the resolution adopted last year. Invitations from the board of directors and president of Girard col- lege for orphans, inviting the members of the association to visit that institution, were read and accepted. The resolution of the American philosophical society, tendering the use of their hall for the meetings of the association, also one of the board of managers of the Pennsylvania hospital, offering their library for the same purpose, were read. Lawrence Lewis, Mordecai L. Dawson and William Biddle took seats with the association, as members of the board of managers of the Pennsylvania hospital for the insane, also William Bettle and John C* Allan, as managers of the Friends' asylum. A paper prepared by Dr. Gait, of the Eastern asylum of Virginia, on the impropriety of treating the insane and persons affected with other disorders, in the same building, was read by Dr. Hanbury Smith, and after discussion, on motion of Dr. Butler, was laid on the table for future notice. Dr. Cutter read a paper on the use of stramonium in the treatment of insanity, which, after discussion, was laid upon the table. Dr. Ray read a case illustrating the great ingenuity often exhibited by the insane in accounting for their delusions. Dr. Worthington tendered to the association an invitation to visit and examine the Friends' asylum for the insane ; and Dr. Kirkbride, a similar one to visit the Pennsylvania hospital for the insane, which invitations were accepted, and referred to the business committee. Dr. Kirkbride made a report from the business committee, which was accepted. On motion of Dr. Parker, adjourned to meet at the Girard college at 4J o'clock this afternoon. Afternoon Session. The association met at the Girard college, agreeably to adjourn- ment, and under the guidance of the directors and officers of that magnificent monument of private charity, proceeded to visit its va- rious parts, and to examine its internal arrangements, and then ad- AMERICAN INSANE INSTITUTIONS. 405 journed to meet at the hall of the American philosophical society, at 9 o'clock to-morrow morning. Second Day — Morning Session. The association met agreeably to adjournment. The minutes of yesterday's sessions were read and adopted. Dr. Edward Jarvis, of Dorchester, (private institution,) Mass., took his seat as a member of the association. Dr. W. H. Stokes, of the Mount Hope asylum, near Baltimore, ap- peared and took his seat as a member of the association. Dr. Charles Evans, consulting physician of the Friends' asylum, also took a seat with the association. J. Konigmacher, as trustee of the Pennsylvania state lunatic hospi- tal at Harrisburg, Alex'r Cummings, W. S. Hansell and T. Robinson, Esq'rs., as guardians of the Philadelphia lunatic asylum, took seats with the association. The secretary, on behalf of the officers of the United States mint, tendered an invitation to the association to visit that institution ; also a similar one from the managers of the Pennsylvania hospital — and from the Pennsylvania institution for the instruction of the blind — from the Pennsylvania institution for the deaf and dumb, and from the Philadelphia athenaeum, which were accepted and referred to the business committee. Dr. Kirkbride, from the business committee, made a report. Dr. Curwen read a paper containing a manual for the use of attend- ants in institutions for the insane, which, after discussion, was laid upon the table. On motion of Dr. Higgins, it was Resolved, That a committee be appointed to examine the manual prepared by Dr. Curwen, and be requested to report during the pre- sent meeting of the association. Drs. Hanbury Smith, Fonerden and Benedict were appointed the committee. On motion of Dr. Hanbury Smith, it was Resolved, That a committee be appointed to draw up a constitution and code of by-laws for the government of the association, and to aid in the despatch of business. Drs. Hanbury Smith, Kirkbride and Nichols were appointed the committee. A letter from Baines Sears, Esq., secretary of the Massachusetts board of education, relative to the preventing of insanity by means of early education, was read and referred to a committee of three, of which Dr. Ray is chairman, with power to select his associates. Dr. Ray read a paper, entitled " Hints to Medical Witnesses in Questions of Insanity," when, after discussion, on motion of Dr. Kirk- bride, it was Resolved, That the paper just read by Dr. Ray is of so practical and valuable a character, that he be requested to publish it in the American Journal of Insanity, as containing the sentiments of this as- sociation on the subject to which it refers. 406 AMERICAN INSANE INSTITUTIONS. Dr. Hanbury Smith, from the committee on publication, made a report, in which was recommended the publication of a volume of transactions, containing the history of the rise and progress of the as- sociation, an abstract of its proceedings, and a selection from the papers read at its annual meetings. On motion of Dr. Kirkbride, the subject was referred back to the same committee to make a fur- ther report at a future session. A communication was received from a committee of the board of guardians of the Philadelphia almshouse, inviting the association to visit that institution, which was read, accepted, and referred to the business committee. The paper prepared by Dr. Gait, and laid on the table yesterday, was called up for discussion, after which, Dr. Patterson offered the following resolution, viz : Resolved, That it is the duty of the community to provide and suita- bly care for all classes of the insane, and that in order to secure their greatest good and highest welfare, it is indispensable that institutions for their exclusive care and treatment, having a resident medical su- perintendent, should be provided, and that it is improper, except from extreme necessity, as a temporary arrangement, to confine insane per- sons in county poorhouses or other institutions, with those afflicted with or treated for other diseases, or confined for misdemeanors; which, on motion of Dr. Parker, was laid on the table for future con- sideration. Dr. Earle commenced reading an account of several institutions for the insane on the continent of Europe, visited by him two years since, and suspended the reading on a motion to adjourn to meet at the Pennsylvania hospital for the insane, at 2 o'clock P. M., which was agreed to. Afternoon Session. The association met agreeably to adjournment. Dr. Chandler of the Massachusetts state lunatic hospital appeared and took his seat as a member of the association. Under the guidance of Dr. Kirkbride, the association proceeded to visit and examine the Pennsylvania hospital for the insane, and then adjourned to meet at the hall of the American philosophical society, at 9 o'clock to-morrow morning. Third Day. — Morning Session. The association met agreeably to adjournment. The minutes of yesterday's proceedings were read and adopted. Dr. Ranney, of Blackwell's Island lunatic asylum, took his seat as a member of the association. Dr. Earle concluded the reading of his paper, interrupted by the adjournment yesterday morning. An invitation from Dr. Horner to visit the University of Pennsylva- nia and Wistar Museum, was read, accepted and referred to the busi- ness committee. AMERICAN INSANE INSTITUTIONS. 407 Dr. Kirkbride, from the standing committee on the construction of hospitals for the insane, in compliance with the resolution adopted last year, read a report containing a " series of resolutions or propositions, affirming the well-ascertained opinions of this body in reference to the fundamental principles which should regulate the erection and in- ternal arrangements of American hospitals for the insane." I. Every hospital for the insane should be in the country, not with- in less than two miles of a large town, and easily accessible at all seasons. II. No hospital for the insane, however limited its capacity, should have less than fifty acres of land devoted to gardens and pleasure grounds for its patients. At least one hundred acres should be pos- sessed by every state hospital or other institution for 200 patients, to which number these propositions apply, unless otherwise mentioned. III. Means should be provided to raise ten thousand gallons of water daily to reservoirs that will supply the highest parts of the building. IV. No hospital for the insane should be built without the plan having been first submitted to some physician or physicians who nave had charge of a similar establishment, or are practically acquainted with all the details of their arrangements, and received his or their full approbation. V. The highest number that can with propriety be treated in one building is two hundred and fifty, while two hundred is a preferable maximum. VI. All such buildings should be constructed of stone or brick, have slate or metallic roofs, and as far as possible be made secure from ac- cidents by fire. VII. Every hospital, having provision for two hundred or more pa- tients, should have in it at least eight distinct wards for each sex — making sixteen classes in the entire establishment. VIII. Each ward should have in it a parlor, a corridor, single lodg- ings for patients, an associated dormitory communicating with a cham- ber for two attendants ; a clothes-room, a bath-room, a water-closet, a dining-room, a dumb-waiter, and a speaking-tube leading to the kitchen or other central part of the building. IX. No apartments should ever be provided for the confinement of patients or as their lodging rooms that are not entirely above ground. X. No class of rooms should ever be constructed, without some kind of window in each communicating directly with the external at- mosphere. XI. No chamber for the use of a single patient should ever be less than eight by ten feet, nor should the ceiling of any story occupied by patients be less than twelve feet in height. XII. The floors of patients' apartments should always be of wood. XIII. The stairways should always be of iron, stone or other inde- structible material, ample in size and number, and easy of ascent, to afford convenient egress in case of accident from fire. XIV. A large hospital should consist of a main central building with wings. 408 AMERICAN INSANE INSTITUTIONS. XV. The main central building should contain the offices, receiving rooms for company, and apartments entirely private for the superin- tending physician and his family, in case that officer resides in the hospital building. XVI. The wings should be so arranged, that if rooms are placed on both sides of a corridor, the corridors should be furnished at both ends with movable glazed sashes for the free admission of both light and air. XVII. The lighting should be by gas, on account of its convenience, cleanliness, safety and economy. XVIII. The apartments for washing clothing, &c, should be de- tached from the hospital building. XIX. The drainage should be under ground, and all the inlets to the sewers should be properly secured to prevent offensive emana- tions. XX. All hospitals should be warmed by passing an abundance of pure fresh air from the external atmosphere, over pipes or plates, con- taining steam under low pressure, or hot water, the temperature of which at the boiler does not exceed 212 degrees F., and placed in the basement or cellar of the building to be heated. XXI. A complete system of forced ventilation, in connection with the heating, is indispensable to give purity to the air of a hospital for the insane, and no expense that is required to effect this object tho- roughly, can be deemed either misplaced or injudicious. XXII. The boilers for generating steam for warming the building should be in a detached structure, connected with which may be the engine for pumping water, driving the washing apparatus, and other machinery. XXIII. All water closets should as far as possible be made of in- destructible materials — be simple in their arrangement, and have a strong downward ventilation connected with them. XXIV. The floors of bath-rooms, water-closets, and basement sto- ries, should as far as possible be made of materials that will not ab- sorb moisture. XXV. The wards for the most excited class should be constructed with rooms on but one side of a corridor, not less than ten feet wide, the external windows of which should be large, and having pleasant views from them. XXVI. Wherever practicable, the pleasure grounds of a hospital for the insane should be surrounded by a substantial wall, so placed as not to be unpleasantly visible from the building. Which propositions having been duly read, and maturely consi- dered, were adopted by the association. On motion of Dr. Hanbury Smith, it was Resolved, That the secretary be instructed to cause the propositions now adopted, in reference to the construction and arrangements of hospitals for the insane, to be published in the medical journals of this continent, as the sentiments of this association on the subject re- ferred to. AMERICAN INSANE INSTITUTIONS. 409 On motion of Dr. Smith, of Missouri, it was Resolved, That a committee be appointed in reference to the best kinds of furniture for hospitals for the insane, to report, if possible, during the present meeting of the association. Drs. Buttolph, Benedict and Curwen were appointed the commit- tee. Dr. Fonerden offered the following resolution, viz : Resolved, (1st.) That when a hospital for 250 patients has received 200, a new hospital ought to be erected in anticipation of the time when the maximum number will be in possession of all the accom- modations. (2nd.) The second hospital ought then to be constructed, with a view to appropriate it to one sex of patients only, and as soon as it is ready for admission, there should be transferred to it from the first hospital all the patients of that sex for which the new hospital has been provided. Dr. Benedict moved a division of the question, which was agreed to. The first section, relative to the erection of a second hospital, was adopted. The second section, relative to appropriating the new hos- pital to a single sex, being under consideration, on motion of Dr. Kirk- bride, it was Resolved, That the whole subject be referred to a committee, to re- port at the meeting next year. Drs. Fonerden, Benedict and Chandler, were appointed the com- mittee. On motion of Dr. Patterson, the resolution offered b}f him yesterday was taken up for consideration, and after discussion, was adopted. On motion of Dr. Worthington, adjourned to meet at the Friends' asylum for the insane, at 3J P. M. Afternoon Session. The association met at the Friends' asylum agreeably to adjourn- ment, and having, under the guidance of Dr. Worthington, examined the different parts of that establishment, came to order for the trans- action of business. Dr. Chandler read a paper on the proper number of patients for one institution, and whether any advantages would result from a com- plete separation of the sexes, in hospitals devoted to their treatment, which after discussion was laid upon the table. Adjourned to meet at the Philosophical hall, at 11 o'clock to-mor- row morning. Fourth Day. — Morning Session. After having visited in a body the United States mint and the Aca- demy of natural sciences, the association met agreeably to adjourn- ment. The minutes of yesterday's proceedings were read and adopted. Dr. Nichols read a paper prepared by Dr. Williams, one of the consulting physicians of Blackwell's Island hospital, N. Y., on typho- mania, which after discussion was laid on the table. 47 410 AMERICAN INSANE INSTITUTIONS. Dr. Kirkbride read a paper on the washing, laundry, bakehouse, &c. for hospitals for the insane, which after discussion was laid upon the table. Dr. Jarvis read a paper on the supposed increase of insanity, which after discussion was laid upon the table. Dr. Kirkbride tendered his resignation of the office of secretary, to take effect at the close of the present meeting, which was accepted. On motion of Dr. Benedict, a committee was appointed to nomi- nate a member to supply the vacancy occasioned by the resignation of Dr. Kirkbride. Drs. Benedict, Hanbury Smith and Worthington were appointed the committee. Dr. Chandler commenced the reading of an obituary notice of the late Samuel B. Woodward, M. D., the first president of this associa- tion, and prepared at the request of last meeting. Dr. Hanbury Smith moved that a committee of finance be ap- pointed, which was agreed to* Drs. Hanbury Smith, Kirkbride and Butler were appointed. The finance committee made a report, which was accepted. Adjourned to meet at the Philadelphia hospital for the insane, Blockley, at 4 P. M. Afternoon Session. After having visited the Pennsylvania hopital in the city of Phila- delphia, the first institution provided in America for the treatment of the insane, being founded just a century ago, the association, under the guidance of Dr. Haines, proceeded to inspect the different parts of the Philadelphia lunatic hospital and almshouse, Blockley. On motion of Dr. Fonerden, it was Resolved, That a committee of three be appointed to decide upon the place of the next meeting of the association. Drs. Kirkbride, Parker and Patterson were appointed the com- mittee. Dr. Hanbury Smith, from the committee relative to the manual for attendants, offered the following resolution, which was adopted, viz : Resolved, That Dr. Curwen, when printing his manual, be requested to supply each member of the association with an interleaved copy, and that these copies, with what remarks may be suggested during the year, be handed to the committee before making a final report next year. Adjourned to meet at the Philosophical hall, at 9 o'clock to-morrow morning. Fifth Day. — Morning Session. The association met agreeably to adjournment. On motion of Dr. Nichols, it was Resolved, That a committee be appointed to express the thanks of this association to the various boards of managers and officers of the different institutions visited by the association, as well as to the va- rious other bodies to whom we are indebted for invitations and other acts of kindness. AMERICAN INSANE INSTITUTIONS. 411 Drs. Nichols, Hanbury Smith, and Smith of Missouri, were ap- pointed the committee. On motion of Dr. Worth ington, it was Resolved, That the members of the association be requested to re- port to the next meeting all the fatal cases of that form of disease described by Dr. Bell in his paper read before this association in 1849, and other cases resembling it, together with the result of their autop- sies, especial reference being had to the condition of the thoracic, ab- dominal and pelvic viscera, as well as to that of the brain. Dr. Kirkbride, from the committee to select a place for the next meeting, reported that they had agreed to recommend that when the association adjourns, it will adjourn to meet in the city of New York on the 3d Tuesday of May 1852, at 10 o'clock, A. M., which recom- mendation was adopted. On motion of Dr. Fonerden, it was Resolved, That Dr. Ray be chairman of the committee in reference to Mr. Sears' letter, and that he nominate his associates. 2nd. That the secretary of this association write to the secretary of the Massa- chusetts board of education, informing him that his letter of June 22d, 1850, to Dr. Fonerden, was read at a meeting of the association held 19th May 1851, and then referred to a committee to report at the an- nual meeting in 1852. Dr. Chandler finished the reading of his notice of the late Dr. Woodward, interrupted by the adjournment yesterday, when, on mo- tion of Dr. Kirkbride, it was Resolved, That Dr. Chandler be requested to publish the memoir in the American Journal of Insanity. Dr. Buttolph offered the following resolutions, which were unani- mously adopted, viz : Resolved, That this association fully appreciates the benevolent mo- tives, the self-sacrificing labors, and the untiring perseverance of Miss D. L. Dix, in her efforts to ameliorate the condition of the insane of our country, and that we deeply regret the failure during the last and previous session of congress, of her application to that body for an appropriation of a portion of the public lands, for the benefit of the indigent insane of the several states. Resolved, That we do now, as we have heretofore done, most cor- dially recommend the passage of this act by congress, believing as we do, that the measure would be alike creditable to the benevolent character of our government and people, and useful to the unfortu- nate recipients of the bounty. Resolved, That Miss Dix be encouraged by our advice and sympa- thy to continue her application in behalf of this object until her efforts are crowned with success, and that the secretary be requested to fur- nish her with a copy of these resolutions. The treasurer, Dr. Kirkbride, reported : That since the last meet- ing he had received $18, and had paid expenses of the association to the amount of $12 59, leaving in his hands a balance of $6 73. On motion of Dr. Fonerden, it was Resolved, That the president of the association be requested to open 412 AMERICAN INSANE INSTITUTIONS. the next meeting with a public address on the progress of knowledge concerning insanity. Dr. Nichols, in compliance with the request of the last meeting of the association, read an obituary notice of the late Amariah Brigham, M. D., one of its vice-presidents, when on motion of Dr. Kirkbride, it was Resolved, That Dr. Nichols be requested to publish the same in the American Journal of Insanity. Dr. Haines read a paper descriptive of the system of steam heat- ing, connected with a forced ventilation adopted at the hospital build- ings of the Philadelphia almshouse, which after discussion was laid upon the table. On motion of Dr. Hanbury Smith, the committee on a constitution and bye-laws was continued, to report at the next meeting. On motion of Dr. Smith of Missouri, it was Resolved, That a committee of three be appointed to report at the next meeting of the association, on the relative value of an upward and downward ventilation in hospitals for the insane. Drs. Bell, Smith of Missouri, and Haines, were appointed the com- mittee. Dr. Ray made a statement in reference to an act passed by the last legislature of the state of Rhode Island, defining the legal relations of the insane of that commonwealth. Dr. Nichols, from the committee appointed for the purpose, re- ported the following resolutions, which, after consideration, were una- nimously adopted, viz : Resolved, That the members of this association have visited and in- spected the Pennsylvania hospital for the insane, under the care of Dr. Kirkbride, as well as the parent institution in the city of Philadel- phia, with great interest and satisfaction, recognising in both abundant evidence of the well-directed benevolence to which they owe their origin, and feeling convinced that, if not unequalled, they are at least unexcelled. Resolved, That upon a close inspection of the Friends' asylum for the insane, near Frankford, under the care of Drs. Evans and Worth- ington, the association has much pleasure in testifying to the excellent condition in which they found that well-conducted and now venerable institution. Resolved, That the visit of the members of the association to the Philadelphia hospital and lunatic asylum in Blockley, under the me- dical care of Dr. Haines, has afforded them an opportunity of avow- ing their conviction that this establishment occupies a. prominent posi- tion among the great charities which are the glory of Philadelphia. The cleanliness and comfort of its spacious apartments, the classifica- tion, order, and freedom from restraint of its insane inmates, are commendable ; and in all that relates to the supply of water, warmth, ventilation and drainage, this institution is not only in advance of si- milar pauper establishments, but even of some of our state hospitals. Resolved, That while the association finds so much to admire and commend in this institution, and approvingly observes the astonishing AMERICAN INSANE INSTITUTIONS. 413 improvements effected since its last meeting in this city, six years ago, it feels free to remind the board of guardians, of its well-known opi- nions on the importance of providing labor, and spacious and con- stantly and readily accessible grounds for exercise for the insane, es- pecially as the institution possesses abundant means of accomplishing such advisable improvements, in the extensive grounds and beautiful gardens connected with it. Resolved, That our thanks are especially due to the boards of ma- nagers and guardians of all the institutions above mentioned for their personal attentions and the kindness shewn us on the occasion of the visit of inspection, to which reference has just been made, as well as other times, and for other proffered privileges, of which want of time has prevented our availing ourselves. Resolved, That our thanks are due and afe hereby tendered to the president and directors of the Girard college for orphans, for the libe- ral manner in which the association was entertained during its visit to every part of that magnificent and admirably conducted institution. Resolved, That the association returns its warmest thanks to Dr. R. M. Patterson, director, and Franklin Peale, Esq., chief coiner of the United States mint, for the highly appreciated privilege afforded us of inspecting every part of this establishment, justly renowned for the elegance and perfection of its machinery and arrangements, and for the admirable manner in which it is conducted. Resolved, That the association gratefully acknowledges the liberality and kindness which prompted the American philosophical society to tender its hall for the meetings of the association, and the use of which places us under special obligations to that body. Resolved, That the thanks of the association are also due to the managers of the Pennsylvania hospital for the offer of their beautiful library room for the meetings of the association : to the officers of the academy of natural sciences, for the privilege of making a very gra- tifying visit to that valuable institution : to the officers of the Penn- sylvania institution for the instruction of the blind, of the Pennsylva- nia institution for the deaf and dumb, of the Philadelphia Athenaeum, and of the University of Pennsylvania, for the courteous invitations to visit those institutions, which want of time alone prevented our ac- cepting. Resolved, That the secretary be requested to furnish the daily papers of Philadelphia with a copy of these resolutions for publication. The committee appointed to select a secretary in the place of Dr. Kirkbride, resigned, nominated Dr. Buttolph, who was appointed. On motion of Dr. Hanbury Smith, it was Resolved, That while the association reluctantly accepts the resigna- tion of its secretary, Dr. Thomas S. Kirkbride, it feels that it is due, not only to him but to itself, to express its full appreciation of the faith- ful, devoted and acceptable manner in which he has discharged the duties, often arduous and irksome, of the office which he has filled from the first organization of the association, and for which we return him our heart-felt thanks. Dr. Hanbury Smith, from the committee on publication, asked that said committee be continued ; which was agreed to. 414 SELECTIONS. On motion of Dr. Parker, it was Resolved, That the thanks of the association are cordially tendered to its vice-president, Dr. I. Ray, for the able, impartial and courteous manner in which he has performed the duties of presiding officer du- ring the present meeting. On motion of Dr. Benedict, it was Resolved, That the president of the association be requested (within two months of the adjournment of the present meeting) to assign to each member a subject on which he shall make a written report at the next meeting. On motion of Dr. Nichols, it was Resolved, That the secretary be requested to furnish a copy of the proceedings of the association to the editor of the " American Journal of Insanity," and to the editors of the various medical journals in the United States and Canada, for publication in their respective journals. After some remarks by the vice-president, Dr. Ray, on motion of Dr. Butler, The association adjourned to meet in the city of New York, on the third Tuesday in May 1852, at 10 o'clock A. M. THOMAS S. KIRKBR1DE, Secretary. Ovarian Tumor Removed, per vias Naturales, by Catheterism of the Fallopian Tubes. REPORTED BY SAMUEL A. CARTWRIGHT, M. D., NEW ORLEANS. March 10th, 1850, I sent for Dr. Warren Stone, to consult him in regard to the propriety of extirpating a very large and hard ovarian tumor in a patient of mine, Mrs. * * *, a small, delicately-formed lady, of sanguine temperament and scrofulous constitution, lately from the country. The patient herself wanted an operation performed, and came to the city for that purpose. When I told her that it would re- quire an incision two feet long to extirpate so large a tumor, she re- plied, that she did not care if it were three feet, as she had rather die than live to suffer as she did. A tormenting strangury, from the pres- sure of the tumor on the bladder, annoyed her very much day and night. She was about 19 years of age, had been married two years, and was very feeble, pale and emaciated. She said that the tumor had been growing from her earliest recollection, but it had not become so large as to incommode her much, until after her marriage ; she had taken iodine and its preparations for a long time ; had been twice sa- livated, and so far from deriving any benefit, grew weaker and the tu- mor continued to enlarge. She was also afflicted with bronchitis and ulceration of the throat, which she attributed to salivation. The tu- mor made her look as large as a woman in the ninth month of preg- nancy ; it was hard and irregular to the touch, and seemed to arise from the left ovarium ; it would incline from side to side with the po- sition of the body ; a prolongation of the tumor had slipped down between the bladder and uterus, and so much compressed the vagina SELECTIONS. 415 as to be in the way of a speculum examination. As the case was beyond the reach of medicine, the resources of surgery were invoked. After a careful examination, Dr. Stone came to the conclusion that a surgical operation would be too hazardous, and in all probability fatal, in consequence of adhesion of the tumor to the bladder and conti- guous viscera. The patient was put on a course of proto-iodide of mercury, com- bined with cicuta ; the tincture of iodine was applied externally, and a tincture of pareira brava root advised for the relief of the irritation of the bladder. This treatment was continued for seven or eight days, the patient growing weaker and the tumor larger. The disease of the throat became so annoying that I found it necessary to apply the ni- trate of silver frequentty to the ulcerated and inflamed tonsils, and to substitute tonics for the iodide of mercury and cicuta. On the 18th of March, the patient consented to a speculum exami- nation. The uterus was rather under the usual size ; there was no leu- corrhceal discharge, congestion or inflammation ; the mucous surfaces were in a state of anaemia, being pale and exsanguious. A very small gum elastic catheter, with a wire in it, after repeated efforts, was intro- duced into the uterine cavity. The passage of the catheter through the coarctation, called the os internum, gave some pain, and caused a faintish, sick sensation ; but this is nearly always the case in probing a healthy uterus, and the operation requires some address and a pro- per instrument, or it cannot be effected. The small catheter was with- drawn, and a larger-sized instrument was passed with some difficulty through the cavity of the cervix into the uterus ; it penetrated about two inches ; on being withdrawn, a little blood, as usual, followed. I now concluded to try catheterism of the left Fallopian tube. With this view, the catheter, containing a wire, was flexed like the male catheter and passed through the fusiform cavity of the neck into the triangular cavity of the uterus itself; the wire was withdrawn about half an inch, so as to make the point of the instrument more flexible, and was carried forward in the direction of the ostium uterinum of the left Fallopian tube. It entered the tube after a few trials, and after penetrating about an inch, it seemed to enter a cavity or expansion of the tube itself; it was pushed forward about an inch and a half more, seeming in its passage to encounter a soft, yielding substance ; it was then withdrawn ; a glutinous substance followed its withdrawal, which I recognised to be a hydatid formation. The same catheter, with a very tapering point, was dipped in a solution of nitrate of silver, a drachm to an ounce. Several minims of the solution were drawn into it by working the wire in the calibre of the instrument ; it was then passed through the uterine cavity into the Fallopian tube, until it had penetrated the tube three inches, when it was moved about in the ca- vity of the tube, and the wire moved so as to eject the caustic solution through the eyes of the catheter, among the hydatid cysts that the in- strument had reached ; on withdrawing it, a semi-membranous, tena- cious substance, with dark specks interspersed through it, not unlike frog-spawn, presented itself at the mouth of the uterus, seeking an exit, but too thick and glutinous to pass freely. Finding it too soft 416 SELECTIONS. and yielding to be drawn away with the forceps, a little raw cotton was passed around a probe, so as to entangle the viscid substance, and by turning the probe the stringy matter was wound around it, and pulled out of the uterus in long mucilaginous ropes. The supply seemed to be inexhaustible. The patient being much fatigued, the operation of drawing away the hydatids was at length suspended ; nevertheless they continued to come away, per vias naturales, for a week or more. In the mean time, the tumor was reduced to less than half its former size, and grew softer and less painful. The catheterism of the Fallopian tube, with the catheter filled with a strong solution of nitrate of silver, was again repeated on the 3d of April, the 1st, 7th and 13th of May. At the last operation no more hydatids or viscid fluid was brought away ; but at all the other operations, they were not only brought away at the time, but continued to pass off for a week or more after each catheterism. The day after the last operation, the patient left town for the sea- shore ; her health had begun to improve rapidly, her pains were gone, and her abdomen was reduced to near its natural size. While absent, her health appeared to be entirely reinstated. Last autumn she returned to the city quite well, though some fulness and hardness could still be felt in the hypogastric region, the effects of the former adhesions, verifying the accuracy of the diagnosis made by Dr. Stone, of whose skill in surgery New Orleans is justly proud. Soon after her return she had an attack of fever, which, as is usual, sought out the weakest part, and the ovarian region again became the seat of painful sensation, which, with the distension from d}rspeptic flatulence, made her apprehensive, for some months, that she was not cured ; but her general health improved in the course of the winter, and she was enabled to dance, waltz, and walk about town as ac- tively as almost any other woman. Although she suffers somewhat from painful distension in the abdominal and pelvic regions during her menstrual periods, and is dyspeptic and flatulent at such times, yet, when that is over, her form is quite sylph-like. Her bronchial disease is cured, and the leucophlegmasia is giving way to the rosy hue pro- per to her original sanguine temperament. As this is the first case of ovarian tumor, as far as I know, which has been treated by catheterism of the Fallopian tubes, I have thought proper to report it. I do not consider the operation as always a diffi- cult one ; because, when the ovaries are in a morbid state, the Fallo- pian tubes are, in general, much more easily catheterized than in the healthy condition. I doubt its practicability in a state of health ; pos- sibly it might be effected during the catamenial period. The same important practical law obtains in regard to the uterus itself, it being generally easier to probe when in a morbid state. I have succeeded in curing some cases of dysmenorrhea and sterility by catheterism of the Fallopian tubes, selecting the proper time for the operation ; but as its virtues in this respect are already known to the profession, it is unnecessary to dwell upon the subject farther than to say, that New Orleans can shew some as unquestionable evidences of its efficacy in sterility as London. — New Orleans Medical and Surgical Journal. SELECTIONS. 417 Repudiation of Homoeopathic Members by the Edinburgh College of Physicians. We are glad to learn from the following that "the authorities" in Edinburgh begin to see the necessity of purging their body of the Hahnemannic entozoa which defile their prima, via. It was high time for them, parties as they have been by toleration to a diffusion of this form of medical tergiversation amongst the rising generation educated in this ancient establishment. We are not for dictating to the better dressed mob on the choice of their medical advisers; we think that a fool has a right to his physician, but we have a right to dictate to colleges which by connivance place knaves on a level with honest men. The Edinburgh College of Physicians is entitled to credit for their movement in this direction ; but to those unacquainted with the varieties which exist in the medical body politic, it is necessary to state that it forms no part of the Universily ; neither, we believe, has it any connection with it. The University appears powerless in this as in many other matters deeply affecting the welfare and character of the medical profession, being under the control of the town council: a strange arrangement still adhered to notwithstanding its origin. Surely it is high time for the Scotch to emancipate themselves from the authority of the uncivilized barbarians who ruled them when these charters were granted. The following is the act of the College of Physicians : " Resolutions unanimously adopted by the Royal College of Physicians of Edinburgh, regarding Practitioners of Homoeopathy. "At Edinburgh, and within the College Hall there, the 9th day of May 1S51, an extraordinary meeting of the Ro}ral College was held, pursuant to a resolution agreed to at the last quarterly meeting, and of which extraordinary meeting due notice was given, the president in the chair, the following resolutions were moved, seconded, and unanimously agreed to: " I. That the Royal College of Physicians of Edinburgh, did, several years ago, publicly express its opinion of homoeopathy and homoeopathic practitioners, by peremptorily declining to admit into its body a candidate for its fellowship who belonged to that denomi- nation ; and consequently that no fellow of the college can possibly be ignorant of the light in which all those who practise homoeopathy are regarded by the college. " II. The college regrets that, notwithstanding this decided expres- sion of its opinion, more than one of its fellows, after being admitted in a different character, have endangered the reputation of the college by becoming homoeopathic practitioners ; and the college expresses an earnest hope th;it these fellows, seeing they have thus virtually separated themselves from the college, will spontaneously sever their further connection with an institution which repudiates them, and from which they can derive, as merely nominal fellows, nothing else than a false position and a spurious credit. 48 418 SELECTIONS. " III. The college feels the more bound thus to express its opinion, seeing that those fellows who have become homoeopathists, and any other medical practitioners who follow homceopaihy, must necessarily be aliens to the other fellows, and to the profession at large ; inas- much as no fellow of this college, or any other physician, can, by any possibility, without derogating from his own honour and from the honour of the profession, meet practitioners of homoeopathy in con- sultation, or co-operate with them in the other common duties of pro- fessional life. "IV. That although the college has not thought it expedient hitherto to take any active steps tor disclaiming those fellows who have become homoeopathic practitioners subsequently to their admis- sion to the college, nevertheless, since it has the power of dealing summarily with ihose who act in a manner so unbecoming the cha- racter of a physician, it reserves its right to exercise that power when it shall be so advised. Signed in name, and by authority of the college. J. Y. Simpson, President." We add the comments of the London Lancet, in which we concur. The homoeopathic branch of the valetudinary section of the com- munity will, doubtless, say that this "persecution" of their infinitesi- mal part of a medical man is mere spite ; and will babble of Harvey, Galileo and Jenner, but when such iblk tire of their plaything, we do not wish to find it in our cabinet : " The College of Physicians of Edinburgh has just come to a reso- lution condemnatory of the practice of homoeopathy, and calling upon any of its fellows or licentiates who may look with favor on that silly heresy, to disconnect themselves from a body instituted for the cultiva- tion and promotion of science. It is, we believe, well understood to be the purpose of the Northern college to proceed against all such per- sons as may shew themselves slow to understand what honor and truth require of them. They will be plainly^ and forcibly ejected. Nor will those be spared who, in weak compliance with aristocratic caprice, and in order to steal a march upon their more sturdy and honest competitors, so far forget what is due to their education, their position, and their duty to their patients, as to countenance and meet in consultation the pseudo-medical tribe who, under the gabardine of homoeopaths, wait upon the weaknesses, and stoop to the humors of pampered and idle men and women of the upper ranks of society. All honor to the College of Physicians of Edinburgh. We trust they will neither waver nor pause in their manly and honest course. It is time that the medical profession should rouse itself to vindicate both its character and its property. Toleration has gone far enough, and the evil but grows with impunity. We have in this metropolis, to a still greater extent than in Edinburgh, our impostors, and we regret to say, also our false brothers, who d:> us more injury than the quacks. Were the homoeopaths invariably left in the difficulties into which their, presumption and their dishonesty frequently lead them, iheir SELECTIONS. 419 credit with the public would long ago have been destroyed. But when physicians of hitherto good name consent to meet such men, and thus vouch for the propriety of their proceedings, they are vastly aided in their scandalous and nefarious trade. We regret to think that in London, men attending members of the royal family have been singularly guilty in this respect. We should be glad to hear that our own College of Physicians had roused itself to the evil which is stalk- ing abroad. The monstrous alliances now proceeding between regu- lars and quacks, might surely deserve the exertion of collegiate authority. The Edinburgh College will not, we trust, forget that there are great functionaries to be corrected. What is to be done with Dr. Henderson, the homoeopathic professor of pathology in the University of Edinburgh, to the condign disgrace of the university, and of every other professor, be it spoken? What sort of pathology does this man teach? If he teach the pupils of the university the ordinary and approved doctrines of physic, what becomes of his prac- tice? If he teach ihem homoeopathy, what excuse have the patrons for the toleration ? In either case, " Ou l'honneur va-t-elie se nicher." " We are not aware what steps have yet been taken by the College of Physicians of Edinburgh in the matter of Professor Henderson, the homoeopathic pathologist of the great Northern university. We trust no hesitation will be felt by the college respecting his summary punishment. This person has too long been permitted to scandalize the medical profession in Scotland. We have always held it mon- strous that a man perverted from legitimate medicine should be allowed to tamper with medical youth, in his professional character, for a single year after his perversion. It is discreditable to the moral feeling of the profession in Edinburgh that a man should have been permitted to continue year after year in the opposite and incompatible characters of homoeopathic practitioner and medical teacher in a uni- versity for the education of students in the rules of legitimate medicine. We know it has been said again and again, that the professorial ap- pointment lies with the town council, and that that body alone is capable of removing Professor Henderson from his chair of pathology. But the profession have had no indications of discontent on the part of the other professors at the humiliating position in wnich they have long been placed. They might, and should, one and all have re- signed, unless the correction of Dr. Henderson could have been effected. How can such men as Goodsir, Christison, and Hughes Bennett, reconcile it to their consciences that they hold their profes- sorial offices conjointly with a homoeopath ? This is worse than meeting homoeopathic practitioners in practice, for teaching is a higher matter lh;in practice. For some time past the principal professors of the University of Edinburgh have advertised themselves as editors of the Monthly Journal of Medicine. We have not observed their criti- cisms upon the state of the prof ssion in Edinburgh, or the anomalous position of Professor Henderson. We have seen plenty of captious mult-finding with respect to everything passing in London; but the beam in the medical eye of Edinburgh has quite escaped attention. This is hardly as it should be, atid we beg to call the notice of the 420 SELECTIONS. gentlemen to whom we have referred, to their duties as editors and professors. Let them bestow their pens for a while north of the Tweed, and let us have the pleasure of congratulating them upon the removal of the scandal which now deforms their veteran university." [Dublin Medical Press. Extraordinary Tapping. Dr. T. D. Lee, of New York, reports a case of ascites, in which he performed paracentesis abdominis 39 times, and drew off 141 gal- lons of water! The case terminated fatally. We recollect removing 10 gallons at one tapping, in a case of encysted dropsy, and re- peatedly afterwards 6 gallons, by which the life of the patient was prolonged about 18 months. — [Southern Med. and Surg. Journal. »I»i«A& §§11111 ©F OMlOx SESSION OF 1851-'52. The thirty-second annual session of this institution will open on the 15th of October next, and close on the last of February, under the following arrange- ments : H. W. Baxley, M. D., Professor of Anatomy. John Locke, M. D., Professor of Chemistry and Pharmacy. L. M. Lawson, M. D., Professor of Physiology and Pathology. T. O. Edwards, M. D., Professor of Materia Medica and Therapeutics and Medical Jurisprudence. R. D. Mussey, M. D., Professor of Surgery. Landon C. Rives, M. D., Professor of Obstetrics and the Diseases of Wo- men and Children. John Bell, M. D., Professor of Theory and Practice of Medicine. John Davis, M. D., Demonstrator of Anatomy. EF*The following branches will be included in the course : Anatomy, Chemis- try, Pharmacy, Physiology, Pathology, Materia Medica, Therapeutics, Medical Ju- risprudence, Medical Botany, Surgery, Obstetrics, Diseases of Females, Diseases of Children, Practical Medicine and Clinical Medicine and Surgery. G^The Dissecting Rooms will be opened for classes on the 1st of October. fa?" Clinical Lectures on Medicine and Surgery will be delivered at the Com- mercial Hospital three times a week. The Medical College of Ohio affords the most ample opportunities for the pro- secution of practical Anatomy and clinical instructions in Medicine and Surgery. Preliminary Lectures. A course of Lectures will be delivered by the faculty, (free of charge,) com- mencing on the 1st of October; also, Clinical Lectures at the Commercial Hospital. FEES. — For a full course of Lectures $105; Matriculation and Library ticket, $5; Dissecting ticket, $10; Graduation fee, $25 ; Hospital ticket, $ 5. ESP Board (including the expenses of room, fuel and light) can be obtained at from $2 to $3 per week. EF" A new college edifice will be erected during the ensuing summer. Further information may be obtained by addressing the Dean. L. M. LAWSON, M. D., Dean of the Faculty, South side of 6th st., between Walnut and Vine. Cincinnati, July 1851. — tO. HEBI9A1 ftS$£&¥»Sn OF S41^®®1JJ asanas CM&Gi&&«n« RICHMOND, VA, The fourteenth annual course of lectures will commence on Monday, the 13th of October 1851, and continue until the 1st of the ensuing March. The com- mencement for conferring degrees will be held about the middle of March. R. L. Bohannan, M. 1)., Prof, of Obstetrics and Diseases of Women and Chil- dren. L. W. Chamberlayne, M. D., Prof, of Materia Medica and Therapeutics. S. Maufin, M, D., Prof, of Chemistry and Pharmacy. Chas. Hell Gibson, M. D., Prof. Surgery and Surgical Anatomy. Carter P. Johnson, M. D., Prof, of Anatomy and Physiology. David H. Tucker, M. D., Prof, of Theory and Practice of Medicine. Arthur E. Pkticolas, M. D., Demonstrator of Anatomy. The study of practical Anatomy may be prosecuted with the most ample faci- lities, and at very trifling expense. Clinical lectures are regularly given at the college infirmary and Richmond almshouse. The infirmary, under the same roof with the college, and subject to the entire control of the faculty, is at all times well filled with medical and surgical cases, and furnishes peculiar facilities for clinical instruction. Many surgical ope- rations are performed in presence of the class ; and the students being freely ad- mitted to the wards, enjoy, under the guidance of the professors, unusual oppor- tunities for becoming familiar with the symptoms, diagnosis and treatment of dis- eases. Expenses. — Matriculation fee, $5. Professors' fees, $105. Demonstrator's fee, $10. Graduation fee. $25. The price of board, including fuel, lights and servants' attendance, is usually $3 or $3£ per week. The catalogue, &c, containing fuller information concerning the institution, will be forwarded to those applying for it, or specific enquiries will be answered by letter. Address, S. MAUPIN, M. D., July 1st, 1851. Dean of the Faculty. ILL, LADD & CO. ilHjolcsaU a\\b fUtail DRUGGISTS, No. 92, corner of Main and 14th Streets, RICHMOND, VA. KEEP CONSTANTLY ON HAND A LARGE AND GENERAL ASSORTMENT OF FRESH AND RELIABLE DRffiS, MEDIGmSS; French, English, German and American Chemicals; Surgical instruments, Physicians' Saddle Bags; PAINTERS' COLOItS, OILS, DYE-STUfFS, WINDOW GLASS, ETC. We are c ireful in the selection of articles, and endeavor to offer none but those of reli- able quality and known purity. rW Particular attention is given to the preparation and procuring of ALL NEW PHARMACEUTICAL PREPARATIONS and CM MICALS. which are added as they are introduced so as to render our stock at all times complete and desirable. Our facilities enable us to oiler to purchasers such inducements as will give satisfaction. GF* Orders promptly and carefully atteuded to. PURE MEDICINAL EXTRACTS. WE WOULD CALL THE ATTENTION OF PHYSICIANS, APOTHECARIES AND DRUGGISTS, TO OUR LIST OF :TmiL(BTi AND ANNEXED TESTIMONIALS. rs&r a& i^sw tais. Inspissated Alcoholic and Hydro-Alcoholic Extracts. Aconite. Butternut. Belladonna. Bitter Root. Boneset. Burdock. Blood Root. Blue Flag. Boxwood. Conium. Camomile. Cohosh, black. " blue. Clover. Cowparsnip. Dandelion. Digitalis. Dulcamara. Dock, yellow. Gargei, or Poke. Gentian. Hyoscyamus. Hardhack. Hops. Hellebore, black. " white. Horehound. Indian Hemp. Lettuce, garden. " wild. Lobelia. Mandrake. Malefern. Mullein. Oak, white. " black. " red. Poppy. Princess Pine. Rue. Savin. Sarsaparilla — American com- pound. " Rio Negro. " Compound. Thornapple. Wormwood. And other varieties frequently used, as soon as they can be reached. Extract from a letter of Professor Clark, of the College of Physicians and Surgeons of New York, to the editor of the New York Journal of Medicine. " I have lately visited the manufactory of these extracts. After inspecting the whole process, and examining a large number of preparations, I became so fully persuaded that these gentlemen have fallen upon the best plan of concentrating and preserving the active principles, especially of the narcotic vegetables, that I have voluntarily offered to them any assistance that I can render in introducing their medicines to the notice of the profession ; being persuaded that these extracts must jmssess the efficiency and the uniformity of strength so necessary to the successful use of this class of remedies, and, I may add, so long sought for in vain. " Should your conviction of the value of these preparations correspond with my own, after you have examined them and tried them in practice, perhaps you may think it due alike to the profession and to the gentlemen who are improving the instruments by which we work, to call the attention of your readers to the improvements which I cannot doubt this process secures." " Medical Society of the State of New York. " Resolved, That this society, having seen and examined, and several of them having used the various Vegetable Extracts made by Messrs. Tilden & Co., of New Lebanon, New York, and being satisfied of the valuable character of these preparations, hereby re- commend them to the members of the profession generally. "P. VAN BUREN, Secretary. " Albany, February 6, 1850." Massachusetts Medical Society for the Berkshire District, June 21, 1850. Resolved, That this society, having seen from various sources entitled to respect ;md con- fidence, commendatory notices of the excellency and purity of the various medicinal extracts prepared by the Messrs. Tilden, of New Lebanon. New York, and having tested them and used them ourselves, do most cordially recommend diem to the medical profession. H. H. CHILOS President pro tern., And President of the Berkshire Medical College. For sale in Richmond, Virginia, by the Agents, FURCSSLL, LADD & Co., Druggists, 92 Main street, corner 14th. BMI & TOMKDW, 139 MAIN STREET, RICHMOND, VA. Uljeal fjetmstwlj) in BOOKS, STATIONERY, AND HAM fiBVUk In the department of MEDICAL LITERATURE, they devote particular attention in keeping up a full supply of the Standard Works, as well as the late publications, and offer them for sale as low as they can be had in any regular establishment in the United States. They furnish all the Medical Periodicals. 5QP1 English, French and German Books imported to order, with care and despatch. (LATE DRINKER & MORRIS,) Wholesale Booksellers, Stationers, Publishers, and Dealers in Piano Fortes, Music, Musical Merchandise, Fancy Goods, &c, &c. 97 MAIN STREET, RICHMOND, VA,, Are constantly supplied with the most important publications in every department of literature, the arts and sciences. Orders from private individuals, schools, colleges, academies, semi- naries of learning, or other public institutions for Books, Stationery, Piano Fortes, Sfc, tip., will be furnished on the most favorable terms, and with the greatest despatch. Foreign books imported to order. FIANO FORTES. Morris & Brother are the sole agents for the sale of Worcester's unrivalled Inslrvmcnts, and in evidence of their superiority beg to sub- mit to a discriminating public the following testimonial: Improvement in Pianos. — New York is fully entitled to the credit of having effected the greatest real improvements in the construction of that noblest of all instruments, the Piano. Some others may have added to the sweetness of certain parts of their instruments at the cost of the power and brilliancy of the whole; while others again have lavished money upon the fanlistic decorations of the frames; but to our fellow-citizen Worcester, whose Pianos have latterly made way so rapidly into public favor, belongs the merit of increasing at the same time the power, quality and endurance of tone, and without a corresponding exaggeration of price. — New York Mirror. ROBERT M'NAMEE, MAKER OF H If III I pre MAIN STREET, opposite American Hotel, Asks the attention of Physicians and Dentists to his stock, which will be found to comprise all kinds of Dental anl Surgical Instruments, Trusses, Cutlery, &c. He likewise makes to order and repairs all descriptions of Instruments. Thankful for the liberal patronage he has already received, he trusts to be able to merit a continuance of it, by increased business facilities, and a determination to give entire satisfaction to his patrons. Afiii a hi APOTHECARIES AND DRUGGISTS, Richmond, Va., (SUCCESSORS TO ALEXANDER DUVAL,) Dealers in all kinds of Medicinal Preparations, English, French, German and American Chemicals of the most approved makers. Also, the well known Pharmaceutical Prepara- tions of Herring & Brothers of London, Howard & Kent, Morson and others. Surgical and Dentists' Instruments, Paints, Oils, Dyes, Window Glass, Perfumery, Brushes, &c,